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2024-04-25 02:33:19, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_030925 3691 bp mRNA linear PRI 16-JUN-2013
DEFINITION Homo sapiens calcium binding protein 39-like (CAB39L), transcript
variant 1, mRNA.
ACCESSION NM_030925 NM_001031724
VERSION NM_030925.2 GI:118766349
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3691)
AUTHORS Zhang,W.J., Zhang,W.G., Zhang,P.Y., Cao,X.M., He,A.L., Chen,Y.X.
and Gu,L.F.
TITLE The expression and functional characterization associated with cell
apoptosis and proteomic analysis of the novel gene MLAA-34 in U937
cells
JOURNAL Oncol. Rep. 29 (2), 491-506 (2013)
PUBMED 23135622
REMARK GeneRIF: In conclusion, our current results provide new evidence
that MLAA-34 may be a novel anti-apoptotic factor in vitro, and the
data presented here show a strong correlation between
anti-apoptosis with the upregulation of MLAA-34.
REFERENCE 2 (bases 1 to 3691)
AUTHORS Zhao,J., He,A., Zhang,W., Meng,X. and Gu,L.
TITLE Quantitative assessment of MLAA-34 expression in diagnosis and
prognosis of acute monocytic leukemia
JOURNAL Cancer Immunol. Immunother. 60 (4), 587-597 (2011)
PUBMED 21240483
REMARK GeneRIF: our data indicate that MLAA-34 may be used as a prognostic
marker for treatment decision-making in acute monocytic leukemia
REFERENCE 3 (bases 1 to 3691)
AUTHORS Zhang,P.Y., Zhang,W.G., He,A.L., Wang,J.L. and Li,W.B.
TITLE Identification and functional characterization of the novel acute
monocytic leukemia associated antigen MLAA-34
JOURNAL Cancer Immunol. Immunother. 58 (2), 281-290 (2009)
PUBMED 18592235
REMARK GeneRIF: It was proposed that a splice variant MLAA-34 of CAB39L
associated with acute monocytic leukemia. MLAA-34 was identified
and characterized. Identification and functional characterization
of the novel acute monocytic leukemia associated antigen MLAA-34
REFERENCE 4 (bases 1 to 3691)
AUTHORS Kahn,B.B., Alquier,T., Carling,D. and Hardie,D.G.
TITLE AMP-activated protein kinase: ancient energy gauge provides clues
to modern understanding of metabolism
JOURNAL Cell Metab. 1 (1), 15-25 (2005)
PUBMED 16054041
REMARK Review article
REFERENCE 5 (bases 1 to 3691)
AUTHORS Dunham,A., Matthews,L.H., Burton,J., Ashurst,J.L., Howe,K.L.,
Ashcroft,K.J., Beare,D.M., Burford,D.C., Hunt,S.E.,
Griffiths-Jones,S., Jones,M.C., Keenan,S.J., Oliver,K., Scott,C.E.,
Ainscough,R., Almeida,J.P., Ambrose,K.D., Andrews,D.T.,
Ashwell,R.I., Babbage,A.K., Bagguley,C.L., Bailey,J., Bannerjee,R.,
Barlow,K.F., Bates,K., Beasley,H., Bird,C.P., Bray-Allen,S.,
Brown,A.J., Brown,J.Y., Burrill,W., Carder,C., Carter,N.P.,
Chapman,J.C., Clamp,M.E., Clark,S.Y., Clarke,G., Clee,C.M.,
Clegg,S.C., Cobley,V., Collins,J.E., Corby,N., Coville,G.J.,
Deloukas,P., Dhami,P., Dunham,I., Dunn,M., Earthrowl,M.E.,
Ellington,A.G., Faulkner,L., Frankish,A.G., Frankland,J.,
French,L., Garner,P., Garnett,J., Gilbert,J.G., Gilson,C.J.,
Ghori,J., Grafham,D.V., Gribble,S.M., Griffiths,C., Hall,R.E.,
Hammond,S., Harley,J.L., Hart,E.A., Heath,P.D., Howden,P.J.,
Huckle,E.J., Hunt,P.J., Hunt,A.R., Johnson,C., Johnson,D., Kay,M.,
Kimberley,A.M., King,A., Laird,G.K., Langford,C.J., Lawlor,S.,
Leongamornlert,D.A., Lloyd,D.M., Lloyd,C., Loveland,J.E.,
Lovell,J., Martin,S., Mashreghi-Mohammadi,M., McLaren,S.J.,
McMurray,A., Milne,S., Moore,M.J., Nickerson,T., Palmer,S.A.,
Pearce,A.V., Peck,A.I., Pelan,S., Phillimore,B., Porter,K.M.,
Rice,C.M., Searle,S., Sehra,H.K., Shownkeen,R., Skuce,C.D.,
Smith,M., Steward,C.A., Sycamore,N., Tester,J., Thomas,D.W.,
Tracey,A., Tromans,A., Tubby,B., Wall,M., Wallis,J.M., West,A.P.,
Whitehead,S.L., Willey,D.L., Wilming,L., Wray,P.W., Wright,M.W.,
Young,L., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E., Beck,S.,
Bentley,D.R., Rogers,J. and Ross,M.T.
TITLE The DNA sequence and analysis of human chromosome 13
JOURNAL Nature 428 (6982), 522-528 (2004)
PUBMED 15057823
REFERENCE 6 (bases 1 to 3691)
AUTHORS Lee,S.Y., Obata,Y., Yoshida,M., Stockert,E., Williamson,B.,
Jungbluth,A.A., Chen,Y.T., Old,L.J. and Scanlan,M.J.
TITLE Immunomic analysis of human sarcoma
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 100 (5), 2651-2656 (2003)
PUBMED 12601173
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
DB279812.1, BC010993.2, AA278473.1, AL138875.8 and CA450475.1.
On or before Dec 6, 2006 this sequence version replaced
gi:72534733, gi:13569886.
##Evidence-Data-START##
Transcript exon combination :: BC010993.2 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025082 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-236 DB279812.1 1-236
237-683 BC010993.2 1-447
684-1104 AA278473.1 59-479
1105-1674 BC010993.2 869-1438
1675-3148 AL138875.8 70004-71477 c
3149-3691 CA450475.1 1-543 c
FEATURES Location/Qualifiers
source 1..3691
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="13"
/map="13q14.2"
gene 1..3691
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/note="calcium binding protein 39-like"
/db_xref="GeneID:81617"
/db_xref="HGNC:20290"
/db_xref="MIM:612175"
exon 1..467
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/inference="alignment:Splign:1.39.8"
variation 34
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/replace="a"
/replace="g"
/db_xref="dbSNP:199582872"
misc_feature 355..357
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/note="upstream in-frame stop codon"
exon 468..609
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/inference="alignment:Splign:1.39.8"
CDS 499..1512
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/note="sarcoma antigen NY-SAR-79; antigen MLAA-34;
U937-associated antigen; mo25-like protein; MO25beta"
/codon_start=1
/product="calcium-binding protein 39-like"
/protein_id="NP_112187.2"
/db_xref="GI:118766350"
/db_xref="CCDS:CCDS9416.2"
/db_xref="GeneID:81617"
/db_xref="HGNC:20290"
/db_xref="MIM:612175"
/translation="
MKKMPLFSKSHKNPAEIVKILKDNLAILEKQDKKTDKASEEVSKSLQAMKEILCGTNEKEPPTEAVAQLAQELYSSGLLVTLIADLQLIDFEGKKDVTQIFNNILRRQIGTRSPTVEYISAHPHILFMLLKGYEAPQIALRCGIMLRECIRHEPLAKIILFSNQFRDFFKYVELSTFDIASDAFATFKDLLTRHKVLVADFLEQNYDTIFEDYEKLLQSENYVTKRQSLKLLGELILDRHNFAIMTKYISKPENLKLMMNLLRDKSPNIQFEAFHVFKVFVASPHKTQPIVEILLKNQPKLIEFLSSFQKERTDDEQFADEKNYLIKQIRDLKKTAP
"
misc_feature 514..1500
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/note="Mo25-like; Region: Mo25; pfam08569"
/db_xref="CDD:203985"
exon 610..774
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/inference="alignment:Splign:1.39.8"
exon 775..893
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/inference="alignment:Splign:1.39.8"
variation 776..777
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/replace="a"
/replace="g"
/db_xref="dbSNP:11546263"
exon 894..1062
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/inference="alignment:Splign:1.39.8"
exon 1063..1122
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/inference="alignment:Splign:1.39.8"
exon 1123..1188
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/inference="alignment:Splign:1.39.8"
exon 1189..1332
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/inference="alignment:Splign:1.39.8"
exon 1333..3676
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/inference="alignment:Splign:1.39.8"
STS 1486..1612
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/standard_name="RH103315"
/db_xref="UniSTS:97646"
STS 1693..2511
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/standard_name="CAB39L__4492"
/db_xref="UniSTS:471378"
STS 2285..2444
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/standard_name="RH91905"
/db_xref="UniSTS:87826"
STS 3442..3569
/gene="CAB39L"
/gene_synonym="bA103J18.3; MO25-BETA; MO2L; RP11-103J18.3"
/standard_name="STS-N23383"
/db_xref="UniSTS:57953"
ORIGIN
gtgacgttacaggactgaggagggaggaagtaaaagggagctgtgactgtggtacgtatctgaaagcaagtgttagagagggagtggagaacgcataagcaagctggtttgaccagaaacagaactgcctgtgacagattaagagacaagcaaggcttggaatctgagagcaagcaaagagagtggaaatttacagctgccctatgtgagtgttcaagtgatcattttctggtaacgttttccagtggtaactgttactcttcaaaaagagggacagaaagtcaagacctaattgtggaaactcttttctctgccacgcttggtaataggaggcaacctctattaaatggacgataaaggctacttcatctaaagtgctttgagctcaagaaagagctgtcttcagcacctcaccatgtgtctacattttgttgcttagaaaagcctaggcatttctgtaacatttgcattccatattggaagaagagatttctacacatgaaaaaaatgcctttgtttagtaaatcacacaaaaatccagcagaaattgtgaaaatcctgaaagacaatttggccattttggaaaagcaagacaaaaagacagacaaggcttcagaagaagtgtctaaatcactgcaagcaatgaaagaaattctgtgtggtacaaacgagaaagaacccccaacagaagcagtggctcagctagcacaagaactctacagcagtggcctgctagtgacactgatagctgacctgcagctgatagactttgagggaaaaaaagatgtgacccagatatttaacaacatcttgagaagacagataggcactcggagtcctactgtggagtatattagtgctcatcctcatatcctgtttatgctcctcaaaggatatgaagccccacagattgccttacgttgtgggattatgctgagagaatgtattcgacatgaaccacttgccaaaatcatcctcttttctaatcaattcagagatttctttaagtacgtggagttgtcaacatttgatattgcttcagatgcctttgctactttcaaggatttactaaccagacataaagtgttggtagcagacttcttagaacaaaattacgacactatttttgaagactatgagaaattgcttcagtctgagaattatgttactaagagacagtctttaaagctgctaggggagctgatcctggaccgtcacaactttgccatcatgacaaagtatatcagcaagccggagaacctgaaactcatgatgaacctccttcgggataaaagtcccaacatccagtttgaagcctttcatgtttttaaggtgtttgtggccagtcctcacaaaacacagcctattgtggagatcctgttaaaaaatcagcccaaactcattgagtttctgagcagcttccaaaaagaaaggacggatgatgagcagttcgctgacgagaagaactacttgattaaacagatccgagacttgaagaaaacggccccttgaagagctccccggcccctgtcacagtcagtcgtctcatttgtccagtttgtacagtgtgtcatttcagaaagtcatcattcttgggaagactttggaggtgcctattttttctgctgtaattgttctgggtagatggagtataaacatttgaatggaaaaaaattaacctagaataatatattcattttagtcaagtctgtgattatttatgtgaaatgagaaccattgtatcagatgttgataaaagcaattttaacttgcagatgtgagcccctgggcacaatgagccgctaaatgggagctcaattgacaggcatcaccaagtcttcaaggaggactgagttctcaggggagaactgggaatggggccagggtgcaaaaatgctttgcccatctgtaggtagacacacagatcgctcagggcactgagagatcccagaaggtaacgttaatgttttcagtcattgtgtgtcctttgttgctgccaatgtctttggactgtaatcagtgcatccacacctcccaggatccagtgctccctctcagctcagtctcccctctctccctgtcctgcattccatcccagctcctcagcatggcctcagtgggcgcacccatgcctcccgcagtccaggtgagcaggggagcaactgagcaggaagaggatggatcaacaagggtcacggggaataggggacccacggggtgtgacctgcttgctagagaactgtgaacatgtggctctggatagagtgactgctgctccatattagcttccagagggtgagtgagggacagaatatttccttcataatggtcatgggtgaatgctttctgctgtaagtgtcttttagagtaggaatcagcatagtgggatgcccagcaggcacaaaccatgggtccagggagtctcagcggggaacttctatcagtatcaataaccattggaaggagaaatgattcatgtgtgaaaaaattctcagatccatcaataaatttttttcagagccattgtatcagatgttgataaaagcaatttttttctaataagctgtcattctataattgcccatcacagtctttagtgaacacatagaaagcctatacagttttggtcctgaatagtctcttgtgactaggatgattgaggtgttaattcctcttccttataaaaaggcttggaatcaaaaatattttaaaaggccgtggtttcgtttcagacatcaaccatctaaaacgggattttaaagcgatattttacaagaatgaaaggcacaattgttgatctgtattttttacacttcagtttctaaatcatgaatcgttgccttccacaggaaccctcccttatacattacttgagtgttgtgtagtttttcttcagccaggtatttctctgcctagagaggggaagagaaatgtgttctccaggactgatcccctttgtagattttgtacctgaagagttacctggcagggcaccacccttggctaggcccaggtgtgtgtttctttcttgcctggcatggaccccgaggcaggtgatgtggggcctggcgcacctccccgctttggcagctgtggcctccctggccagtgcccttgcaggaggccggccggcagcctgatgacccgtactctttagtcactgacgtcagattatttttataacgttccctgacagttcagagtcccttcgaattgcacttttctggtttcgcttatttaattaaaagagatgagtgtaagtataaaaaatgaaggtgaaataaccattggaattgtatttggttacttaatactgttccacaacatcttgggacgtctgttttcctttggagagtgaggccttgttattattcttttctgataaagaaaacattttatttcctttgggcttgcattagctctttcctagcaacccattatcccagctcagtacctttcaaacagaaaactagagtctggggttttgttgtgatctgaatttgtaagttattaatgtgaaagggggagcaggaagctccccctttgcacaaagggggatttgtttgcacaaagttcactgtaaatactgtgagaattgaattctgaaaaggtcatatttagtgatttcaaaagcacacatttaaatgaagactgactaaataaaaggtaccacacaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:81617 -> Biological process: GO:0007050 [cell cycle arrest] evidence: TAS
GeneID:81617 -> Biological process: GO:0008286 [insulin receptor signaling pathway] evidence: TAS
GeneID:81617 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
by
@meso_cacase at
DBCLS
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