GGRNA Home | Help | Advanced search

2020-10-26 19:50:58, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_030582               5910 bp    mRNA    linear   PRI 07-JUL-2013
DEFINITION  Homo sapiens collagen, type XVIII, alpha 1 (COL18A1), transcript
            variant 1, mRNA.
ACCESSION   NM_030582 NM_016214
VERSION     NM_030582.3  GI:110611234
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5910)
  AUTHORS   Li,M., Liu,F., Sun,P., Gao,Y., Chen,H., Liu,H., Wang,M., Chen,J.
            and Zhao,Y.
  TITLE     Correlations between serum levels of vascular endothelial growth
            factor and endostatin with clinical pathological characteristics of
            patients with gastrointestinal cancers
  JOURNAL   Hepatogastroenterology 59 (118), 1865-1868 (2012)
   PUBMED   22819906
  REMARK    GeneRIF: Report pre/postoperative endostatin levels in surgically
            treated gastrointestinal cancers.
REFERENCE   2  (bases 1 to 5910)
  AUTHORS   Sunshine,S.B., Dallabrida,S.M., Durand,E., Ismail,N.S., Bazinet,L.,
            Birsner,A.E., Sohn,R., Ikeda,S., Pu,W.T., Kulke,M.H.,
            Javaherian,K., Zurakowski,D., Folkman,J.M. and Rupnick,M.
  TITLE     Endostatin lowers blood pressure via nitric oxide and prevents
            hypertension associated with VEGF inhibition
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 109 (28), 11306-11311 (2012)
   PUBMED   22733742
  REMARK    GeneRIF: Endostatin lowers blood pressure via nitric oxide and
            prevents hypertension associated with VEGF inhibition
REFERENCE   3  (bases 1 to 5910)
  AUTHORS   Melville SA, Buros J, Parrado AR, Vardarajan B, Logue MW, Shen L,
            Risacher SL, Kim S, Jun G, DeCarli C, Lunetta KL, Baldwin CT,
            Saykin AJ and Farrer LA.
  CONSRTM   Alzheimer's Disease Neuroimaging Initiative
  TITLE     Multiple loci influencing hippocampal degeneration identified by
            genome scan
  JOURNAL   Ann. Neurol. 72 (1), 65-75 (2012)
   PUBMED   22745009
REFERENCE   4  (bases 1 to 5910)
  AUTHORS   Chen,Y., Liang,B., Zhao,Y.J., Wang,S.C., Fan,Y.B. and Wu,G.P.
  TITLE     Transcription expression and clinical significance of vascular
            endothelial growth factor mRNA and endostatin mRNA in pleural
            effusions of patients with lung cancer
  JOURNAL   Diagn. Cytopathol. 40 (4), 287-291 (2012)
   PUBMED   22431315
  REMARK    GeneRIF: The detection of VEGF mRNA and endostatin mRNA appears to
            be suitable for distinguishing carcinoma cells from reactive
            mesothelial cells in pleural effusions, they could be useful to
            diagnose the pleural micrometastasis.
REFERENCE   5  (bases 1 to 5910)
  AUTHORS   Wu,X., Wu,J., Xin,Z., Wang,H., Zhu,X., Pan,L., Li,Z., Li,H. and
            Liu,Y.
  TITLE     A 3' UTR SNP in COL18A1 is associated with susceptibility to HBV
            related hepatocellular carcinoma in Chinese: three independent
            case-control studies
  JOURNAL   PLoS ONE 7 (3), E33855 (2012)
   PUBMED   22461898
  REMARK    GeneRIF: Findings indicate that COL18A1 rs7499 may contribute to
            the risk of Hepatocellular carcinoma (HCC) in Han Chinese.
REFERENCE   6  (bases 1 to 5910)
  AUTHORS   Ding,Y.H., Javaherian,K., Lo,K.M., Chopra,R., Boehm,T.,
            Lanciotti,J., Harris,B.A., Li,Y., Shapiro,R., Hohenester,E.,
            Timpl,R., Folkman,J. and Wiley,D.C.
  TITLE     Zinc-dependent dimers observed in crystals of human endostatin
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 95 (18), 10443-10448 (1998)
   PUBMED   9724722
REFERENCE   7  (bases 1 to 5910)
  AUTHORS   Saarela,J., Ylikarppa,R., Rehn,M., Purmonen,S. and Pihlajaniemi,T.
  TITLE     Complete primary structure of two variant forms of human type XVIII
            collagen and tissue-specific differences in the expression of the
            corresponding transcripts
  JOURNAL   Matrix Biol. 16 (6), 319-328 (1998)
   PUBMED   9503365
REFERENCE   8  (bases 1 to 5910)
  AUTHORS   Sertie,A.L., Quimby,M., Moreira,E.S., Murray,J., Zatz,M.,
            Antonarakis,S.E. and Passos-Bueno,M.R.
  TITLE     A gene which causes severe ocular alterations and occipital
            encephalocele (Knobloch syndrome) is mapped to 21q22.3
  JOURNAL   Hum. Mol. Genet. 5 (6), 843-847 (1996)
   PUBMED   8776601
REFERENCE   9  (bases 1 to 5910)
  AUTHORS   Oh,S.P., Kamagata,Y., Muragaki,Y., Timmons,S., Ooshima,A. and
            Olsen,B.R.
  TITLE     Isolation and sequencing of cDNAs for proteins with multiple
            domains of Gly-Xaa-Yaa repeats identify a distinct family of
            collagenous proteins
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 91 (10), 4229-4233 (1994)
   PUBMED   8183893
REFERENCE   10 (bases 1 to 5910)
  AUTHORS   Oh,S.P., Warman,M.L., Seldin,M.F., Cheng,S.D., Knoll,J.H.,
            Timmons,S. and Olsen,B.R.
  TITLE     Cloning of cDNA and genomic DNA encoding human type XVIII collagen
            and localization of the alpha 1(XVIII) collagen gene to mouse
            chromosome 10 and human chromosome 21
  JOURNAL   Genomics 19 (3), 494-499 (1994)
   PUBMED   8188291
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BX322561.1, BC063833.1 and
            AF018082.1.
            This sequence is a reference standard in the RefSeqGene project.
            On Jul 20, 2006 this sequence version replaced gi:18765744.
            
            Summary: This gene encodes the alpha chain of type XVIII collagen.
            This collagen is one of the multiplexins, extracellular matrix
            proteins that contain multiple triple-helix domains (collagenous
            domains) interrupted by non-collagenous domains. The
            proteolytically produced C-terminal fragment of type XVIII collagen
            is endostatin, a potent antiangiogenic protein. Mutations in this
            gene are associated with Knobloch syndrome. The main features of
            this syndrome involve retinal abnormalities, so type XVIII collagen
            may play an important role in retinal structure and in neural tube
            closure. Alternatively spliced transcript variants encoding
            different isoforms have been found for this gene. [provided by
            RefSeq, Sep 2008].
            
            Transcript Variant: This variant (1) is generated from an alternate
            promoter. It lacks an in-frame segment in the 5' exon, as compared
            to variant 3. The resulting isoform (1) lacks an internal segment
            in the N-terminus, as compared to isoform 3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF018081.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025083 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-667               BX322561.1         14592-15258
            668-3998            BC063833.1         142-3472
            3999-5910           AF018082.1         3497-5408
FEATURES             Location/Qualifiers
     source          1..5910
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
                     /map="21q22.3"
     gene            1..5910
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /note="collagen, type XVIII, alpha 1"
                     /db_xref="GeneID:80781"
                     /db_xref="HGNC:2195"
                     /db_xref="MIM:120328"
     exon            1..667
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     CDS             22..4572
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; endostatin; collagen alpha-1(XVIII) chain;
                     antiangiogenic agent; multi-functional protein MFP"
                     /codon_start=1
                     /product="collagen alpha-1(XVIII) chain isoform 1
                     precursor"
                     /protein_id="NP_085059.2"
                     /db_xref="GI:110611235"
                     /db_xref="CCDS:CCDS42972.1"
                     /db_xref="GeneID:80781"
                     /db_xref="HGNC:2195"
                     /db_xref="MIM:120328"
                     /translation="
MAPYPCGCHILLLLFCCLAAARANLLNLNWLWFNNEDTSHAATTIPEPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAPLTGPSVPPPSSERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK
"
     sig_peptide     22..90
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
     mat_peptide     91..4569
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /product="collagen alpha-1(XVIII) chain isoform 1"
     misc_feature    127..573
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /note="Domain of Unknown Function (DUF959); Region:
                     DUF959; pfam06121"
                     /db_xref="CDD:114818"
     misc_feature    760..1248
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /note="Laminin G domain; Laminin G-like domains are
                     usually Ca++ mediated receptors that can have binding
                     sites for steroids, beta1 integrins, heparin, sulfatides,
                     fibulin-1, and alpha-dystroglycans. Proteins that contain
                     LamG domains serve a variety of...; Region: LamG; cl00102"
                     /db_xref="CDD:206838"
     misc_feature    <2515..2640
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /note="Collagen triple helix repeat (20 copies); Region:
                     Collagen; pfam01391"
                     /db_xref="CDD:189968"
     misc_feature    4039..4551
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /note="Endostatin-like domain; the angiogenesis inhibitor
                     endostatin is a C-terminal fragment of collagen XV/XVIII,
                     a proteoglycan/collagen found in vessel walls and basement
                     membranes; this domain has a compact globular fold similar
                     to that of C-type lectins; Region: Endostatin-like;
                     cd00247"
                     /db_xref="CDD:29322"
     misc_feature    order(4132..4134,4159..4161,4177..4179,4204..4209,
                     4216..4218,4402..4407,4435..4437)
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:29322"
     variation       50
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:368343259"
     variation       77
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:7277693"
     variation       103
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375363285"
     variation       111
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200976185"
     variation       112
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369389768"
     variation       141
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:914230"
     variation       152
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199984023"
     variation       156
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368696106"
     variation       163
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:61749002"
     variation       167
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:61735029"
     variation       192
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200354859"
     variation       200
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199929202"
     variation       211
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373586271"
     variation       220
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375087150"
     variation       257..258
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:375958675"
     variation       260
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:61739237"
     variation       312
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201529109"
     variation       321
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370812546"
     variation       324
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149777818"
     variation       333
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377623821"
     variation       337
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375714903"
     variation       345
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370000815"
     variation       351
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374634058"
     variation       352
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114139997"
     variation       369
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:62000459"
     variation       393
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372080967"
     variation       394
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200559406"
     variation       419
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368269918"
     variation       451
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61759533"
     variation       523
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:201773944"
     variation       535
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368985827"
     variation       536
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200284308"
     variation       538
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:62000960"
     variation       558
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:73386835"
     variation       559
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148957774"
     variation       561
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373353645"
     variation       581
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142892701"
     variation       592
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369474928"
     variation       603
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372854150"
     variation       609
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:199717521"
     variation       621
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201419516"
     variation       622
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199725915"
     variation       660
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2236451"
     exon            668..1212
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       679
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375719577"
     variation       687
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:115800039"
     variation       711
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:190083327"
     variation       717
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373105258"
     variation       727
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375009748"
     variation       737
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200842530"
     variation       747
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372731688"
     variation       748
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377002382"
     variation       778
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370054491"
     variation       787
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:374084790"
     variation       802
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:76658745"
     variation       803
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371058906"
     variation       849
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149578781"
     variation       856
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199918230"
     variation       857
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375588763"
     variation       858
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368228266"
     variation       871
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:112855834"
     variation       876
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201508976"
     variation       897
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61735014"
     variation       902
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373861758"
     variation       905
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367715239"
     variation       913
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200702024"
     variation       928
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376829205"
     variation       953
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368606628"
     variation       954
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372142063"
     variation       981
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:17004775"
     variation       1011
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367852328"
     variation       1012
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201833726"
     variation       1021
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375242667"
     variation       1028
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369275624"
     variation       1029
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372556095"
     variation       1035
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377547341"
     variation       1049
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376036984"
     variation       1057
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144281842"
     variation       1071
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:76754353"
     variation       1139
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2236453"
     variation       1159
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370834739"
     variation       1161
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374980607"
     variation       1164
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:17004776"
     variation       1165
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373735265"
     variation       1173
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373748503"
     variation       1174
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201116208"
     variation       1185
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:76148908"
     variation       1187
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:376944366"
     exon            1213..1299
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1215
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369219412"
     variation       1221
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189093550"
     variation       1228
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:60162212"
     variation       1232
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200168928"
     variation       1237
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375001641"
     variation       1238
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201095161"
     variation       1252
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202012055"
     variation       1254
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149772252"
     variation       1275
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369721525"
     exon            1300..1359
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1304
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200073359"
     variation       1320
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374330522"
     variation       1328
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:368233273"
     variation       1332
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371736290"
     variation       1336
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376722572"
     variation       1337
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:62000965"
     exon            1360..1489
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1362
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145912433"
     variation       1364
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375414087"
     variation       1365
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368376035"
     variation       1389
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2230686"
     variation       1397
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375411877"
     variation       1398
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2230687"
     variation       1402
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:192075600"
     variation       1407
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2230688"
     variation       1433
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201652671"
     variation       1434
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183924183"
     variation       1435
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:138471288"
     variation       1448
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372308402"
     variation       1458
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376715250"
     variation       1472
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200230216"
     variation       1473
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141548934"
     variation       1476
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:17338853"
     variation       1481
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200882031"
     variation       1486
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369289615"
     variation       1487
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372726135"
     exon            1490..1566
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1523
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372492704"
     variation       1531
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375058072"
     variation       1558
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367882523"
     exon            1567..1782
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1569
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372133935"
     variation       1570
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:76547444"
     variation       1573
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369413748"
     variation       1604
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372859456"
     variation       1612
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370176315"
     variation       1618
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369114408"
     variation       1619
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373030953"
     variation       1633
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:62000458"
     variation       1657
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377028409"
     variation       1667
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371330320"
     variation       1698
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374344376"
     variation       1704
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2230689"
     variation       1755
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370965213"
     variation       1764
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375400196"
     variation       1773
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367951949"
     variation       1776
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370283993"
     variation       1782
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368902481"
     exon            1783..1809
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1785
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:13046486"
     variation       1786
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200553372"
     variation       1809
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:185296216"
     exon            1810..1872
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1815
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368594049"
     variation       1818
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:183085141"
     variation       1822
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375265466"
     variation       1827
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113540632"
     variation       1836
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1131100"
     variation       1851
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1131101"
     variation       1853
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201414473"
     variation       1866
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1131102"
     exon            1873..1959
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1884
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201380467"
     variation       1903
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373670175"
     variation       1948
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376357877"
     variation       1951
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61738822"
     exon            1960..2013
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1989
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2236467"
     variation       1990
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375852929"
     variation       1996
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369917403"
     variation       2013
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:373106775"
     exon            2014..2172
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2021
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371292624"
     variation       2044
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375739796"
     variation       2068
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368194132"
     variation       2070
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:112723616"
     variation       2071
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375045387"
     variation       2096
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367836626"
     variation       2101
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:79292579"
     variation       2103
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200106008"
     variation       2108..2109
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:35603970"
     variation       2110
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368600244"
     variation       2116
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:61737706"
     variation       2118
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372703675"
     variation       2134
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375198952"
     variation       2142
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369409660"
     exon            2173..2235
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2176
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375417533"
     variation       2184
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:376461054"
     variation       2195
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:373536407"
     variation       2203
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370509732"
     variation       2235
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181807938"
     exon            2236..2262
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2244
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:75222922"
     variation       2248
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201476017"
     exon            2263..2394
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2321
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199823547"
     variation       2385
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370138639"
     exon            2395..2457
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2400
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369792535"
     variation       2412
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376114537"
     variation       2413
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368967629"
     variation       2426
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:371586411"
     variation       2432
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377286160"
     variation       2442
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370015560"
     variation       2443
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181012655"
     exon            2458..2484
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2466
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199523495"
     variation       2481
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11702425"
     exon            2485..2520
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2496
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367928373"
     variation       2497
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371970491"
     variation       2510
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376627920"
     variation       2511
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61731167"
     variation       2517
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372310838"
     exon            2521..2592
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2542
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:62000962"
     variation       2544
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:375695180"
     variation       2556
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185089648"
     variation       2559
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:62000963"
     variation       2564..2565
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:35277478"
     exon            2593..2628
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2595
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375058430"
     variation       2618
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367841049"
     exon            2629..2718
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2646
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373006940"
     variation       2652
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376084472"
     variation       2660
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370141116"
     variation       2661
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373318899"
     variation       2664
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377652187"
     variation       2678
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:79980197"
     variation       2680
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375408962"
     variation       2682
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377533410"
     variation       2688
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370417664"
     variation       2697
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374390595"
     variation       2699
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367570320"
     variation       2704
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372801767"
     variation       2709
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374522196"
     exon            2719..2748
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2727
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201512380"
     variation       2734
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:116111018"
     variation       2741
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377720407"
     variation       2744
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:58380358"
     exon            2749..2775
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2753
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201805043"
     variation       2757
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:115470104"
     variation       2764
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372137898"
     variation       2775
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199910738"
     exon            2776..2838
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2790
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376292745"
     variation       2815
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370009347"
     variation       2828
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370673713"
     exon            2839..2913
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2854
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371808014"
     variation       2865
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373455911"
     variation       2901
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2230693"
     exon            2914..2940
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2921
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367994730"
     variation       2922
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:371966493"
     variation       2938
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376597265"
     variation       2939
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367551698"
     exon            2941..2994
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2949
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139122081"
     variation       2953
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201566264"
     variation       2957
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376924299"
     variation       2994
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200147240"
     exon            2995..3069
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       3003
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375606333"
     variation       3012
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:368730788"
     variation       3013
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372658384"
     variation       3038
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375575507"
     variation       3039
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369390092"
     variation       3051
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377601838"
     exon            3070..3138
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       3071
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:377444691"
     variation       3079
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372552105"
     variation       3129
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376919554"
     exon            3139..3181
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       3139
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200779516"
     variation       3157
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372312684"
     variation       3162
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374530279"
     exon            3182..3244
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       3184
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371993501"
     variation       3193
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377290522"
     variation       3205
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374976416"
     variation       3210
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369139821"
     variation       3224
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373528509"
     variation       3234
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191481067"
     exon            3245..3288
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       3254
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201753320"
     variation       3255
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:190374248"
     variation       3263..3265
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="ttc"
                     /db_xref="dbSNP:371849586"
     variation       3266
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="ttc"
                     /db_xref="dbSNP:78636159"
     exon            3289..3420
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       3328
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372982447"
     variation       3342
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11544970"
     variation       3343
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:187721798"
     variation       3348
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11544971"
     variation       3360
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370771189"
     variation       3376..3393
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="ggcccccccggcccccca"
                     /db_xref="dbSNP:201180574"
     variation       3383
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="cggcccccc"
                     /db_xref="dbSNP:72301048"
     variation       3385..3393
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="ggcccccca"
                     /db_xref="dbSNP:149296338"
     variation       3393
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:28696990"
     variation       3397
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="cccccaggc"
                     /db_xref="dbSNP:11276732"
     variation       3398
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="cccaggccc"
                     /db_xref="dbSNP:56328291"
     variation       3399..3400
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="cccaggccc"
                     /db_xref="dbSNP:78227997"
     variation       3401
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202106628"
     exon            3421..3565
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       3442
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371106773"
     variation       3448
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374058652"
     variation       3480
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368077149"
     variation       3481
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371933414"
     variation       3486
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375548890"
     variation       3487
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376598650"
     variation       3489
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:367549674"
     variation       3499
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372973695"
     variation       3500
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200299380"
     variation       3513
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369702868"
     variation       3534
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:367651350"
     variation       3554
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375478181"
     exon            3566..3639
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       3574
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201381498"
     variation       3588
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370656151"
     variation       3627
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375254978"
     variation       3628
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367825934"
     exon            3640..3768
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       3659
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199718927"
     variation       3676..3681
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="caggtg"
                     /db_xref="dbSNP:201754608"
     variation       3685
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200427354"
     variation       3694
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201265799"
     variation       3711
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371774034"
     variation       3735
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376728632"
     variation       3747
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374911370"
     variation       3748
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:369018715"
     variation       3750
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377152291"
     exon            3769..3801
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       3782
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200839439"
     variation       3783
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:12483761"
     variation       3794
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199583095"
     exon            3802..4047
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       3826
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:76086392"
     variation       3863
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:187670025"
     variation       3866
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374207420"
     variation       3868
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377620137"
     variation       3893
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:112359725"
     variation       3904
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113268527"
     variation       3910
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372741290"
     variation       3931
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375753362"
     variation       3932
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370102608"
     variation       3939
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377093259"
     variation       3958
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199836125"
     variation       3971
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:372765303"
     variation       3981
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375601931"
     variation       3996
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150227889"
     variation       3999
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1050351"
     variation       4032
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370921955"
     exon            4048..4245
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       4062
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374326288"
     variation       4080
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:9980939"
     variation       4083
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376208451"
     variation       4084
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369592585"
     variation       4089
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:373470254"
     variation       4091
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200484625"
     variation       4101
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370643343"
     variation       4131
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372559352"
     variation       4148
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375590764"
     variation       4159
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371038039"
     variation       4161
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:114276639"
     variation       4162
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144147445"
     variation       4176
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370750158"
     variation       4177
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374880663"
     variation       4182
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368134801"
     variation       4198
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369304666"
     variation       4201
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:371989063"
     variation       4208
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200043539"
     variation       4212
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367565307"
     variation       4217
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201006742"
     variation       4220
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377226690"
     variation       4224
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369895316"
     variation       4225
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:77326997"
     variation       4233
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2838952"
     exon            4246..4361
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       4254
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372684121"
     variation       4271
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:375813847"
     variation       4287
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368913533"
     variation       4295
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373537140"
     variation       4302
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199498978"
     variation       4308
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371424181"
     variation       4309
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374321733"
     variation       4315
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199908300"
     variation       4330
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:12483377"
     variation       4333
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375269967"
     variation       4342
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202104330"
     exon            4362..5894
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       4375
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:61736805"
     variation       4387
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200871316"
     variation       4389
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113315760"
     variation       4403
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202049650"
     variation       4413
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372279165"
     variation       4414
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370953127"
     variation       4452
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375390952"
     variation       4456
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370518474"
     variation       4457
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373708039"
     variation       4472
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61735035"
     variation       4480
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374822514"
     variation       4492
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372436243"
     variation       4508
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375488894"
     variation       4517
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201489582"
     variation       4523
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371861582"
     variation       4524
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:375109205"
     variation       4578
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138930698"
     variation       4587
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:149459132"
     variation       4588
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:7499"
     variation       4596
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369152864"
     variation       4601
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371710532"
     variation       4602
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373537387"
     variation       4605
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376696662"
     variation       4614
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369684141"
     variation       4643
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:8199"
     variation       4699
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369628824"
     STS             4761..4992
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /standard_name="SHGC-8080"
                     /db_xref="UniSTS:7730"
     variation       4785
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143852653"
     variation       4849
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:17004784"
     variation       4863
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148610040"
     variation       4871
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183949177"
     variation       4874
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:17255281"
     variation       4878
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:17004785"
     variation       4912
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:7867"
     variation       4920
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146206934"
     variation       5003
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368394587"
     variation       5011
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371166816"
     variation       5014
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:11544972"
     variation       5346
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370216895"
     variation       5421
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:17255379"
     variation       5424
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:17004786"
     variation       5436
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:186538749"
     variation       5477
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367569832"
     variation       5490
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:117981301"
     STS             5532..5873
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /standard_name="SHGC-12530"
                     /db_xref="UniSTS:98863"
     variation       5615
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:377445664"
     variation       5618
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1063505"
     STS             5650..5876
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /standard_name="SHGC-87711"
                     /db_xref="UniSTS:81506"
     variation       5719..5720
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="ca"
                     /db_xref="dbSNP:143456926"
     variation       5720..5721
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="ca"
                     /db_xref="dbSNP:78063943"
     variation       5720
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201512613"
     variation       5721..5722
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="ca"
                     /db_xref="dbSNP:71868999"
     variation       5721
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1063507"
     variation       5763
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:190947105"
     variation       5790
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144079697"
     variation       5809
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:115900328"
     variation       5819
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:182474443"
     variation       5833
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:78156175"
     polyA_signal    5871..5876
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
     polyA_site      5894
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
ORIGIN      
agctccagccgcactgccccgatggctccctacccctgtggctgccacatcctgctgctgctcttctgctgcctggcggctgcccgggccaacctgctgaacctgaactggctttggttcaataatgaggacaccagccatgcagctaccacgatccctgagccccaggggcccctgcctgtgcagcccacagcagataccaccacacacgtgaccccccggaatggttccacagagccagcgacagcccctggcagccctgagccaccctcagagctgctggaagatggccaggacacccccacttctgccgagagcccggacgcgccagaggagaacattgccggtgtcggagccgagatcctgaacgtggccaaaggcatccggagcttcgtccagctgtggaatgacactgtccccactgagagcttggccagggcggaaaccctggtcctggagactcctgtgggcccccttgccctcgctgggccttccagcaccccccaggagaatgggaccactctctggcccagccgtggcattcctagctctccgggcgcccacacaaccgaggctggcaccttgcctgcacccaccccatcgcctccctccctgggcaggccctgggcaccactcacggggccctcagtgccaccaccatcttcagagcgcatcagcgaggaggtggggctgctgcagctccttggggaccccccgccccagcaggtcacccagacggatgaccccgacgtcgggctggcctacgtctttgggccagatgccaacagtggccaagtggcccggtaccacttccccagcctcttcttccgtgacttctcactgctgttccacatccggccagccacagagggcccaggggtgctgttcgccatcacggactcggcgcaggccatggtcttgctgggcgtgaagctctctggggtgcaggacgggcaccaggacatctccctgctctacacagaaccaggtgcaggccagacccacacagccgccagcttccggctccccgccttcgtcggccagtggacacacttagccctcagtgtggcaggtggctttgtggccctctacgtggactgtgaggagttccagagaatgccgcttgctcggtcctcacggggcctggagctggagcctggcgccgggctcttcgtggctcaggcggggggagcggaccctgacaagttccagggggtgatcgctgagctgaaggtgcgcagggacccccaggtgagccccatgcactgcctggacgaggaaggcgatgactcagatggggcatccggagactctggcagcgggctcggggacgcccgggagcttctcagggaggagacgggcgcggccctaaaacccaggctccccgcgccaccccccgtcaccacgccacccttggctggaggcagcagcacggaagattccagaagtgaagaagtcgaggagcagaccacggtggcttcgttaggagctcagacacttcctggctcagattctgtctccacgtgggacgggagtgtccggacccctgggggccgcgtgaaagagggcggcctgaaggggcagaaaggggagccaggtgttccgggcccacctggccgggcaggccccccaggatccccatgcctacctggtcccccgggtctcccgtgcccagtgagtcccctgggtcctgcaggcccagcgttgcaaactgtccccggaccacaaggacccccagggcctccggggagggacggcacccctggaagggacggcgagccgggcgaccccggtgaagacggaaagccgggcgacaccgggccacaaggcttccccgggactccaggggacgtaggtcccaagggcgacaagggagaccctggggttggagagagagggcccccaggaccccaagggcctccagggcccccaggaccctccttcagacacgacaagctgaccttcattgacatggagggatctggcttcgggggcgatctggaggccctgcggggtcctcgaggcttccctggacctcccggaccccccggtgtcccaggcctgcccggcgagccaggccgctttggggtgaacagctccgacgtcccaggacccgccggccttcctggtgtgcctgggcgcgagggtccccccgggtttcctggcctcccgggacccccaggccctccgggaagagaggggcccccaggaaggactgggcagaaaggcagcctgggtgaagcaggcgccccaggacataaggggagcaagggagcccccggtcctgctggtgctcgtggggagagcggcctggcaggagcccccggacctgctggaccaccaggcccccctgggccccctgggcccccaggaccaggactccccgctggatttgatgacatggaaggctccggggggcccttctggtcaacagcccgaagcgctgatgggccacagggacctcccggcctgccgggacttaagggggatcctggcgtgcctgggctgccgggggcgaagggagaagttggagcagatggagtccccgggttccccggcctccctggcagagagggcattgctgggccccaggggccaaagggagacagaggcagccggggagaaaagggagatccagggaaggacggagtcgggcagccgggcctccctggcccccccggacccccgggacctgtggtctacgtgtcggagcaggacggatccgtcctgagcgtgccgggacctgagggccggccgggtttcgcaggctttcccggacctgcaggacccaagggcaacctgggctctaagggcgaacgaggctccccgggacccaagggtgagaagggtgaaccgggcagcatcttcagccccgacggcggtgccctgggccctgcccagaaaggagccaagggagagccgggcttccgaggacccccgggtccatacggacggccggggtacaagggagagattggctttcctggacggccgggtcgccccgggatgaacggattgaaaggagagaaaggggagccgggagatgccagccttggatttggcatgaggggaatgcccggccccccaggacctccagggcccccaggccctccagggactcctgtttacgacagcaatgtgtttgctgagtccagccgccccgggcctccaggattgccagggaatcagggccctccaggacccaagggcgccaaaggagaagtgggcccccccggaccaccagggcagtttccgtttgactttcttcagttggaggctgaaatgaagggggagaagggagaccgaggtgatgcaggacagaaaggcgaaaggggggagcccgggggcggcggtttcttcggctccagcctgcccggcccccccggccccccaggcccacgtggctaccctgggattccaggtcccaagggagagagcatccggggccagcccggcccacctggacctcagggaccccccggcatcggctacgaggggcgccagggccctcccggccccccaggccccccagggcccccttcatttcctggccctcacaggcagactatcagcgttcccggccctccgggcccccctgggccccctgggccccctggaaccatgggcgcctcctcaggggtgaggctctgggctacacgccaggccatgctgggccaggtgcacgaggttcccgagggctggctcatcttcgtggccgagcaggaggagctctacgtccgcgtgcagaacgggttccggaaggtccagctggaggcccggacaccactcccacgagggacggacaatgaagtggccgccttgcagccccccgtggtgcagctgcacgacagcaacccctacccgcggcgggagcacccccaccccaccgcgcggccctggcgggcagatgacatcctggccagcccccctcgcctgcccgagccccagccctaccccggagccccgcaccacagctcctacgtgcacctgcggccggcgcgacccacaagcccacccgcccacagccaccgcgacttccagccggtgctccacctggttgcgctcaacagccccctgtcaggcggcatgcggggcatccgcggggccgacttccagtgcttccagcaggcgcgggccgtggggctggcgggcaccttccgcgccttcctgtcctcgcgcctgcaggacctgtacagcatcgtgcgccgtgccgaccgcgcagccgtgcccatcgtcaacctcaaggacgagctgctgtttcccagctgggaggctctgttctcaggctctgagggtccgctgaagcccggggcacgcatcttctcctttgacggcaaggacgtcctgaggcaccccacctggccccagaagagcgtgtggcatggctcggaccccaacgggcgcaggctgaccgagagctactgtgagacgtggcggacggaggctccctcggccacgggccaggcctcctcgctgctggggggcaggctcctggggcagagtgccgcgagctgccatcacgcctacatcgtgctctgcattgagaacagcttcatgactgcctccaagtagccaccgcctggatgcggatggccggagaggaccggcggctcggaggaagcccccaccgtgggcagggagcggccggccagcccctggccccaggacctggctgccatactttcctgtatagttcacgtttcatgtaatcctcaagaaataaaaggaagccaaagagtgtatttttttaaaagtttaaaacagaagcctgatgctgacattcacctgccccaactctcccctgacctgtgagcccagctgggtcaggcagggtgcagtatcatgccctgtgcaacctcttggcctgatcagaccacggctcgatttctccaggatttcctgctttgggaagccgtgctcgccccagcaggtgctgacttcatctcccacctagcagcaccgttctgtgcacaaaacccagacctgttagcagacaggccccgtgaggcaatgggagctgaggccacactcagcacaaggccatctgggctcctccagggtgtgtgctcgccctgcggtagatgggagggaggctcaggtccctggggctagggggagccccttctgctcagctctgggccattctccacagcaaccccaggctgaagcaggttcccaagctcagaggcgcactgtgacccccagctccggcctgtcctccaacaccaagcacagcagcctggggctggcctcccaaatgagccatgagatgatacatccaaagcagacagctccaccctggccgagtccaagctgggagattcaagggacccatgagttggggtctggcagcctcccatccagggcccccatctcatgcccctggctgggacgtggctcagccagcacttgtccagctgagcgccaggatggaacacggccacatcaaagaggctgaggctggcacaggacatgcggtagccagcacacagggcagtgagggagggctgtcatctgtgcactgcccatggacaggctggctccagatgcagggcagtcattggctgtctcctaggaaacccatatccttaccctccttgggactgaaggggaaccccggggtgcccacaggccgccctgcgggtgaacaaagcagccacgaggtgcaacaaggtcctctgtcagtcacagccacccctgagatccggcaacatcaacccgagtcattcgttctgtggagggacaagtggactcagggcagcgccaggctgaccacagcacagccaacacgcacctgcctcaggactgcgacgaaaccggtggggctggttctgtaattgtgtgtgatgtgaagccaattcagacaggcaaataaaagtgaccttttacactgaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:80781 -> Molecular function: GO:0005198 [structural molecule activity] evidence: IEA
            GeneID:80781 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:80781 -> Molecular function: GO:0042802 [identical protein binding] evidence: IPI
            GeneID:80781 -> Molecular function: GO:0046872 [metal ion binding] evidence: IEA
            GeneID:80781 -> Biological process: GO:0001525 [angiogenesis] evidence: IEA
            GeneID:80781 -> Biological process: GO:0001886 [endothelial cell morphogenesis] evidence: IEA
            GeneID:80781 -> Biological process: GO:0007155 [cell adhesion] evidence: IEA
            GeneID:80781 -> Biological process: GO:0007601 [visual perception] evidence: TAS
            GeneID:80781 -> Biological process: GO:0008284 [positive regulation of cell proliferation] evidence: IEA
            GeneID:80781 -> Biological process: GO:0008285 [negative regulation of cell proliferation] evidence: TAS
            GeneID:80781 -> Biological process: GO:0009887 [organ morphogenesis] evidence: TAS
            GeneID:80781 -> Biological process: GO:0022617 [extracellular matrix disassembly] evidence: TAS
            GeneID:80781 -> Biological process: GO:0030198 [extracellular matrix organization] evidence: TAS
            GeneID:80781 -> Biological process: GO:0030335 [positive regulation of cell migration] evidence: IEA
            GeneID:80781 -> Biological process: GO:0030574 [collagen catabolic process] evidence: TAS
            GeneID:80781 -> Biological process: GO:0043065 [positive regulation of apoptotic process] evidence: IEA
            GeneID:80781 -> Cellular component: GO:0005576 [extracellular region] evidence: TAS
            GeneID:80781 -> Cellular component: GO:0005581 [collagen] evidence: IEA
            GeneID:80781 -> Cellular component: GO:0005604 [basement membrane] evidence: IEA
            GeneID:80781 -> Cellular component: GO:0005615 [extracellular space] evidence: IDA
            GeneID:80781 -> Cellular component: GO:0005788 [endoplasmic reticulum lumen] evidence: TAS
            GeneID:80781 -> Cellular component: GO:0031012 [extracellular matrix] evidence: IDA
            GeneID:80781 -> Cellular component: GO:0031012 [extracellular matrix] evidence: TAS

by @meso_cacase at DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.