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2020-10-24 06:34:29, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_025191               6670 bp    mRNA    linear   PRI 15-JUN-2013
DEFINITION  Homo sapiens ER degradation enhancer, mannosidase alpha-like 3
            (EDEM3), mRNA.
ACCESSION   NM_025191 NM_017992
VERSION     NM_025191.3  GI:163310724
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6670)
  AUTHORS   Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K.,
            Gibbs,R.A. and Butte,N.F.
  TITLE     Novel genetic loci identified for the pathophysiology of childhood
            obesity in the Hispanic population
  JOURNAL   PLoS ONE 7 (12), E51954 (2012)
   PUBMED   23251661
REFERENCE   2  (bases 1 to 6670)
  AUTHORS   Caramelo,J.J. and Parodi,A.J.
  TITLE     Getting in and out from calnexin/calreticulin cycles
  JOURNAL   J. Biol. Chem. 283 (16), 10221-10225 (2008)
   PUBMED   18303019
  REMARK    Review article
REFERENCE   3  (bases 1 to 6670)
  AUTHORS   Olivari,S. and Molinari,M.
  TITLE     Glycoprotein folding and the role of EDEM1, EDEM2 and EDEM3 in
            degradation of folding-defective glycoproteins
  JOURNAL   FEBS Lett. 581 (19), 3658-3664 (2007)
   PUBMED   17499246
  REMARK    Review article
REFERENCE   4  (bases 1 to 6670)
  AUTHORS   Hirao,K., Natsuka,Y., Tamura,T., Wada,I., Morito,D., Natsuka,S.,
            Romero,P., Sleno,B., Tremblay,L.O., Herscovics,A., Nagata,K. and
            Hosokawa,N.
  TITLE     EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic
            reticulum-associated degradation and mannose trimming
  JOURNAL   J. Biol. Chem. 281 (14), 9650-9658 (2006)
   PUBMED   16431915
REFERENCE   5  (bases 1 to 6670)
  AUTHORS   Mast,S.W., Diekman,K., Karaveg,K., Davis,A., Sifers,R.N. and
            Moremen,K.W.
  TITLE     Human EDEM2, a novel homolog of family 47 glycosidases, is involved
            in ER-associated degradation of glycoproteins
  JOURNAL   Glycobiology 15 (4), 421-436 (2005)
   PUBMED   15537790
  REMARK    Erratum:[Glycobiology. 2005 May;15(5):13G]
REFERENCE   6  (bases 1 to 6670)
  AUTHORS   Olivari,S., Galli,C., Alanen,H., Ruddock,L. and Molinari,M.
  TITLE     A novel stress-induced EDEM variant regulating endoplasmic
            reticulum-associated glycoprotein degradation
  JOURNAL   J. Biol. Chem. 280 (4), 2424-2428 (2005)
   PUBMED   15579471
REFERENCE   7  (bases 1 to 6670)
  AUTHORS   Sood,R., Bonner,T.I., Makalowska,I., Stephan,D.A., Robbins,C.M.,
            Connors,T.D., Morgenbesser,S.D., Su,K., Faruque,M.U., Pinkett,H.,
            Graham,C., Baxevanis,A.D., Klinger,K.W., Landes,G.M., Trent,J.M.
            and Carpten,J.D.
  TITLE     Cloning and characterization of 13 novel transcripts and the human
            RGS8 gene from the 1q25 region encompassing the hereditary prostate
            cancer (HPC1) locus
  JOURNAL   Genomics 73 (2), 211-222 (2001)
   PUBMED   11318611
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB292148.1, DA724785.1, AF288393.1, BC016464.1 and AI521228.1.
            On Dec 19, 2007 this sequence version replaced gi:19923618.
            
            Summary: Quality control in the endoplasmic reticulum (ER) ensures
            that only properly folded proteins are retained in the cell through
            recognition and degradation of misfolded or unassembled proteins.
            EDEM3 belongs to a group of proteins that accelerate degradation of
            misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed
            16431915]).[supplied by OMIM, Mar 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF288393.1, AK315118.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           ERS025081, ERS025082 [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-19                DB292148.1         1-19
            20-337              DA724785.1         1-318
            338-4075            AF288393.1         1-3738
            4076-5501           BC016464.1         1260-2685
            5502-6620           BC016464.1         2687-3805
            6621-6670           AI521228.1         12-61               c
FEATURES             Location/Qualifiers
     source          1..6670
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q25"
     gene            1..6670
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /note="ER degradation enhancer, mannosidase alpha-like 3"
                     /db_xref="GeneID:80267"
                     /db_xref="HGNC:16787"
                     /db_xref="MIM:610214"
     exon            1..419
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    19..21
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /note="upstream in-frame stop codon"
     variation       248
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:3795407"
     CDS             262..3060
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /EC_number="3.2.1.113"
                     /note="ER degradation-enhancing -mannosidase-like protein
                     3; ER degradation-enhancing alpha-mannosidase-like 3;
                     alpha-1,2-mannosidase EDEM3; ER degradation-enhancing
                     alpha-mannosidase-like protein 3"
                     /codon_start=1
                     /product="ER degradation-enhancing alpha-mannosidase-like
                     protein 3 precursor"
                     /protein_id="NP_079467.3"
                     /db_xref="GI:163310725"
                     /db_xref="CCDS:CCDS1363.2"
                     /db_xref="GeneID:80267"
                     /db_xref="HGNC:16787"
                     /db_xref="MIM:610214"
                     /translation="
MSEAGGRGCGSPVPQRARWRLVAATAAFCLVSATSVWTAGAEPMSREEKQKLGNQVLEMFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKFSLTLIDSLDTLVVLNKTKEFEDAVRKVLRDVNLDNDVVVSVFETNIRVLGGLLGGHSLAIMLKEKGEYMQWYNDELLQMAKQLGYKLLPAFNTTSGLPYPRINLKFGIRKPEARTGTETDTCTACAGTLILEFAALSRFTGATIFEEYARKALDFLWEKRQRSSNLVGVTINIHTGDWVRKDSGVGAGIDSYYEYLLKAYVLLGDDSFLERFNTHYDAIMRYISQPPLLLDVHIHKPMLNARTWMDALLAFFPGLQVLKGDIRPAIETHEMLYQVIKKHNFLPEAFTTDFRVHWAQHPLRPEFAESTYFLYKATGDPYYLEVGKTLIENLNKYARVPCGFAAMKDVRTGSHEDRMDSFFLAEMFKYLYLLFADKEDIIFDIEDYIFTTEAHLLPLWLSTTNQSISKKNTTSEYTELDDSNFDWTCPNTQILFPNDPLYAQSIREPLKNVVDKSCPRGIIRVEESFRSGAKPPLRARDFMATNPEHLEILKKMGVSLIHLKDGRVQLVQHAIQAASSIDAEDGLRFMQEMIELSSQQQKEQQLPPRAVQIVSHPFFGRVVLTAGPAQFGLDLSKHKETRGFVASSKPSNGCSELTNPEAVMGKIALIQRGQCMFAEKARNIQNAGAIGGIVIDDNEGSSSDTAPLFQMAGDGKDTDDIKIPMLFLFSKEGSIILDAIREYEEVEVLLSDKAKDRDPEMENEEQPSSENDSQNQSGEQISSSSQEVDLVDQESSEENSLNSHPESLSLADMDNAASISPSEQTSNPTENHETTNLNGECTDLDNQLQEQSETEEDSNPNVSWGKKVQPIDSILADWNEDIEAFEMMEKDEL
"
     sig_peptide     262..384
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Potential; propagated from UniProtKB/Swiss-Prot
                     (Q9BZQ6.2)"
     mat_peptide     385..3057
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /product="ER degradation-enhancing alpha-mannosidase-like
                     protein 3"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9BZQ6.2)"
     misc_feature    436..1755
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /note="Glycosyl hydrolase family 47; Region:
                     Glyco_hydro_47; pfam01532"
                     /db_xref="CDD:201845"
     misc_feature    2251..2628
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /note="PA_EDEM3_like: protease associated domain (PA)
                     domain-containing EDEM3-like proteins. This group contains
                     various PA domain-containing proteins similar to mouse
                     EDEM3 (ER-degradation-enhancing mannosidase-like 3
                     protein). EDEM3 contains a region, similar...; Region:
                     PA_EDEM3_like; cd02126"
                     /db_xref="CDD:80348"
     misc_feature    2503..2511
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /note="PA/protease or protease-like domain interface
                     [polypeptide binding]; other site"
                     /db_xref="CDD:80348"
     misc_feature    3046..3057
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9BZQ6.2);
                     Region: Prevents secretion from ER (Potential)"
     exon            420..465
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     exon            466..566
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     exon            567..606
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     exon            607..719
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     exon            720..873
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     exon            874..1008
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     exon            1009..1114
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     exon            1115..1212
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     exon            1213..1338
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     exon            1339..1422
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     exon            1423..1506
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     exon            1507..1631
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     exon            1632..1797
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     exon            1798..1952
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     exon            1953..2106
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     exon            2107..2298
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     exon            2299..2464
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     variation       2427
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1062994"
     exon            2465..2650
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     exon            2651..6632
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /inference="alignment:Splign:1.39.8"
     variation       3813
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11539922"
     STS             3990..4160
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /standard_name="SHGC-53072"
                     /db_xref="UniSTS:67165"
     variation       4076
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1061508"
     variation       4247
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370437415"
     variation       4315
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201955037"
     STS             5121..5242
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /standard_name="SHGC-76042"
                     /db_xref="UniSTS:4310"
     STS             5129..5248
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /standard_name="RH48990"
                     /db_xref="UniSTS:50718"
     variation       5487
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201976406"
     variation       6052
                     /gene="EDEM3"
                     /gene_synonym="C1orf22"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1046239"
ORIGIN      
gttggggaggcggtttcctagactacgacaccggaaagctgggggaggcgctccgggatactgagggcggagggcggtggcagcgctggcgctggggaccggcttggtggcttcgggaaacagtttggcgccggcggccgtccgtgttactccgcatcccgccccgtctcggcacggctagcagccccctggccaccagcgtccagcaatgtgtctcaccggccgggcgtagcagctgcgcgtgcgcggaaccgcggggccatgagcgaagccggcggccggggctgtgggtccccggttccccagcgagcgcgatggagactagtggcggcgacggccgcgttctgcctggtgtcggccacctccgtgtggacggcgggggccgagcccatgagtagggaggagaaacagaagcttgggaatcaagtactggaaatgtttgatcatgcttatggtaactatatggaacatgcttaccctgctgatgaactcatgcctttaacctgtagaggtcgagttagaggccaagagccaagtcgcggtgacgttgatgatgccttgggaaaattttctctgacactgattgattctttggacactcttgtggttttaaataaaactaaagaatttgaagatgcagtgagaaaagttttaagagatgttaatttagataacgatgtagtcgtatcagtctttgaaacaaacatcagagttcttgggggtcttttgggtgggcactccctggcaatcatgctgaaagaaaaaggtgaatatatgcagtggtacaatgatgaacttctccaaatggcaaagcagttaggttacaaacttttaccggctttcaacactaccagtggccttccttatccaagaattaatttaaagtttggcatcagaaaaccagaagctcggacaggaactgagacagatacctgtacagcttgtgcaggtaccttgatccttgaatttgctgctttaagtcgattcacaggagcaacaatatttgaggaatatgccagaaaagctcttgattttctctgggaaaaaagacagcgaagtagtaatttagtgggcgtgactataaatattcatactggagattgggtacgaaaagatagtggagttggagcagggattgattcatattatgaatatctgttgaaagcctatgtcttgcttggagatgacagttttctggaaagatttaacacacactatgatgccataatgaggtatattagccagccacctcttctacttgatgtgcatatccacaaaccaatgctgaatgctcggacttggatggatgctttgcttgccttcttcccaggcttgcaggtgttaaagggggatattagacctgctattgaaactcatgaaatgttatatcaggtgattaaaaaacacaattttctaccagaggcatttaccacagatttcagagtacactgggctcaacatcctttaaggccagaatttgcagaaagtacctacttcttatataaagctacaggagatccttactaccttgaagtagggaagacacttattgaaaatttaaataaatatgctagagtgccttgcggatttgctgccatgaaggatgttcgtactggaagtcatgaggacagaatggattctttcttcttggctgaaatgtttaaatatctttacctgttatttgctgataaagaagacattatttttgacatagaagattacatctttacaacagaagctcatctgttacctctttggctctctactacaaatcaaagcatctctaaaaagaacacaacctcggaatatacagaactggatgacagtaacttcgattggacttgtccaaatactcagatcctctttcctaatgacccattgtatgctcaaagtattcgtgagcccttgaaaaatgtggtggataagagctgtcctagaggcatcatcagagtagaggagagtttcaggagtggagctaaaccccctctgagagccagagatttcatggccactaaccctgagcatttagaaatcctgaagaagatgggggtgagtttgattcacctcaaagatgggagagtccagttggtccaacatgcaatccaagctgctagttcaatcgacgctgaagatgggttgaggttcatgcaggagatgattgaattgtcaagtcagcaacaaaaagaacagcagctgcctccacgagctgtacaaattgtttcccacccattttttggcagggtagtattgactgctggaccagctcagtttgggctggatctgtctaaacataaagagacaagaggatttgttgcaagcagtaaaccatccaatggttgttcagagcttactaacccagaggcagtgatgggaaaaatcgcactgatacaaagaggacagtgcatgtttgcagaaaaggcacgcaacatccagaatgctggagccattggtggcattgttattgatgacaatgaggggagcagcagtgatactgcccctctgttccagatggcaggtgatggaaaggatacagatgacatcaagatccccatgctgttcttattcagcaaagaaggaagtatcatactggatgccatccgggaatatgaggaggtagaagtgctcctctctgataaagcaaaagatcgagatcctgaaatggaaaatgaagaacaaccatcctctgaaaatgattctcagaatcagagtggtgaacagatttcatcaagttctcaggaggttgatttggttgatcaagagtcttctgaggaaaattctctaaattctcacccagaatcattatctctagcagatatggacaatgctgcaagcatttccccttctgaacagacttctaatcccacagaaaaccatgagactacaaatcttaatggtgaatgtacagatttagataaccagcttcaagaacaatcagaaactgaggaagattccaatcctaatgttagctggggtaaaaaggtccagcctatagactccatattagcagactggaatgaagatatagaagcatttgaaatgatggagaaggatgagctatgacttgctaaacaatctgttggtaggtatttaaaaagaaaaggtaaactgtgtgtggttaatagacatcctaatactaagcaggctttctaatgggaggctttaagtatggtgatgaacaaccacgttctgactggcgtagttatcgtaggaatctggagcatgctgtgttagaattgaccttgtttaaaactgtcccatcaaaaatggaaatccacagttcccccttcaaatgcagcactgcaccaccctgcaacacctcaggccagggaaagattactgagcattcctgcgaaccagatttctgttgtctctggatagacaagaaacaaaattcatttagtagtggagtggggaataggagtttggatagccttctaattaaaggaagctcgcctttcttggttttgggggttagaggctcttttgggaagatgcatccgagtattgtggcattctgattatgctgccttcacaaaacactctaagtgacctaagtggttatgaagcaaatgcatttatggtgaaaacagtctttgctcattgctttctcttgtttcatttagtgacaaatgatcaagatgacttgattttttttccttcttaacaatgtcttttttatttaaaccaaaggtgaagccagtgtactttctcagtgagttctctgcataaagactaatcagtgggaccaggtaaaaaggtcatataatacattgtggagattgcttacttaatacttctgaaaaatggagtaagggagaaactgtaatgttgcaatatgaacctcccattgggccttccatagggaaagctgtgactactctgaaatggaacctagcattatatccttgtagggtagattataaatcatttccagttcatttctcttagaggtgattacctctagccatcagccttactccatcccatgtttggtatgcaatttgagccacaaggctcgtatcgccaacagctatatacattttgttccatttttctgtcttacagagccatgatagaactgtggttagtgagttaaaattcctggagtaactactgtttttctcctttgaaacttaggtttctaaagttgcacctaaggaatctgtcacattttctgttgaatcatggtttttgtttttgtttttaacagatattccttctgatacggacttgaaaattagtgtatggtgacctgtgtttaaaaaaaaaagtacaatacaactacatatagctatatagcttaatgagacttccaccccccccctttttttttttggtttgttgttgttgtagtagtctggtgctggccacatttaagtcttaaaaatttttaaattttgttgttgatgtttgtagacagccctgttgttgaaatcatggctttattcattttatttattttttaaacttgcctgaatttgttctaaaggaatatttaagagacataattttcttctctttaccataacattacacaaaactttttcctaaaacacggttgtgaggtactgatgaggtgtaagtggagctgttaaaaacagcagtgctgtattgcagttatgtatattcgtgtacagtatgtttagatcccaggtaaacatattcttttctgagaggataaatacctgcattcagatattccaggtaaatataattgagtcagggagtagtaaatctgatggagaattcactttggggaggggaaaaagaatagtatgcaagacccttattggcttttaattatacctgaaaccaaaatggatatttttagtctctctgcatgtgagatttggtgtaacaagatagaactataatatatacagtatatggaaggatagatatagtgctttgttcattttaattgcaaagctgccaaaatagttgaagcttaattacttgacttgccttgatttataggactggggcttggagaaaatgagcagatgttcctctaagacatcgattacagaagccttatatacatggatttgattttgtatttgtagctgaaagtcactgttgtctaaaactaacttttctaagttatcaaaacaacctaatttcttttccaacaaggagaacttaatggcatgaaggattgtgtgacacattggaaaagccagcttactgccactctcttcctttggccattagagggaggtgttgcctttcattgacgcttagaagcaaattgttcacttgttaagaaaagtaaatccttaaaaaaagaaaaggaaaaaatttaaccaatttttcttaatacccagaaggaattatactcaatatttccctagttaagaaaagaggagataatgttcgtctaaaaaactccaacgttgtaattacaactctacattcatttacttacttgacatactgccacaaagtagtttttgagttcattaaaaattccaaaggcattagttgttttttttttttttagtgttttgttttttagttaacttttatagacattttagtaacttgctaaagattcaggggattctatgaaaccccgaatttagaaacatctggtctacctcagttaaatgttgactgcttagaaatatagctgaagtgatcaccacagccataaaattgtttaagaaagatttatataatgtttacaaatctggaatcaaggattttagctgaaatcctttaagagatattagagcaagtatttaattcaggtattttcaagttttaaaacttaacctgtttacctactaaaaataaaatagctagtttttttctgcatataaaagttcattgaaatgatatgcccttatttgcaatacttttcccataaagttttaagtgtgaaagaattgtaatttactagatatgtttggtatgggatattttgttaggcaagttttcttttttcttcttaaattgcaataggcttccaaaaagagtataattgtttcagaacaaattaactcttggcattatacgtctccctttttctttacagtattagtaaaaagaaaaattgtacactttctgattttaacttcactaatgtaattactctctcaagaagcttttaaaatttaaattaccatcacacaaccttttttatagtaaagccaacatttgttctctcaccaaaccccatgccaaattcatcatgaagaaagctcagcataagtaattcaaatactgcttataattttagaggggggtagaatttagtaaatattccagccggtcgttttatgcacaaggcttcagtcagaacatagaaaaaaaaaacattctgtgaatgaaatattgtatgttcagattttataaaagacatttttaaaagcccaatttacagccgtatattttcttatgatgtaatttatgaaaaagatgtctgtactaacaggtgctgtaacactactgttgttggattttattgtttggtgataaatgtatacaatatttctaagggaaactatgtactgtgatgtaaaagtctgggcaaaatgtatataatcctgtatataattatgtatttgattataattactgattgtaaagatttaataaaatatgtaaatattccagtttagttttaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:80267 -> Molecular function: GO:0004569 [glycoprotein endo-alpha-1,2-mannosidase activity] evidence: IEA
            GeneID:80267 -> Molecular function: GO:0004571 [mannosyl-oligosaccharide 1,2-alpha-mannosidase activity] evidence: IEA
            GeneID:80267 -> Molecular function: GO:0005509 [calcium ion binding] evidence: IEA
            GeneID:80267 -> Biological process: GO:0006457 [protein folding] evidence: TAS
            GeneID:80267 -> Biological process: GO:0006516 [glycoprotein catabolic process] evidence: IEA
            GeneID:80267 -> Biological process: GO:0006986 [response to unfolded protein] evidence: IEA
            GeneID:80267 -> Biological process: GO:0018279 [protein N-linked glycosylation via asparagine] evidence: TAS
            GeneID:80267 -> Biological process: GO:0043161 [proteasomal ubiquitin-dependent protein catabolic process] evidence: IEA
            GeneID:80267 -> Biological process: GO:0043687 [post-translational protein modification] evidence: TAS
            GeneID:80267 -> Biological process: GO:0044267 [cellular protein metabolic process] evidence: TAS
            GeneID:80267 -> Cellular component: GO:0005788 [endoplasmic reticulum lumen] evidence: IEA
            GeneID:80267 -> Cellular component: GO:0005789 [endoplasmic reticulum membrane] evidence: TAS
ANNOTATIONS from NCBI Entrez Gene (20130726):
            NP_079467 -> EC 3.2.1.113

by @meso_cacase at DBCLS
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