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2024-03-29 17:41:58, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_024670               3093 bp    mRNA    linear   PRI 18-APR-2013
DEFINITION  Homo sapiens suppressor of variegation 3-9 homolog 2 (Drosophila)
            (SUV39H2), transcript variant 3, mRNA.
ACCESSION   NM_024670
VERSION     NM_024670.3  GI:34147611
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3093)
  AUTHORS   Syreeni,A., El-Osta,A., Forsblom,C., Sandholm,N., Parkkonen,M.,
            Tarnow,L., Parving,H.H., McKnight,A.J., Maxwell,A.P., Cooper,M.E.
            and Groop,P.H.
  CONSRTM   FinnDiane Study Group
  TITLE     Genetic examination of SETD7 and SUV39H1/H2 methyltransferases and
            the risk of diabetes complications in patients with type 1 diabetes
  JOURNAL   Diabetes 60 (11), 3073-3080 (2011)
   PUBMED   21896933
  REMARK    GeneRIF: genetic association studies in a Finnish population with
            type I diabetes: The minor T allele of exonic SNP rs17353856 in
            SUV39H2 is associated with diabetic retinopathy (in a larger
            meta-analysis); thus an genetic variation may be protective.
REFERENCE   2  (bases 1 to 3093)
  AUTHORS   Benlhabib,H. and Mendelson,C.R.
  TITLE     Epigenetic regulation of surfactant protein A gene (SP-A)
            expression in fetal lung reveals a critical role for Suv39h
            methyltransferases during development and hypoxia
  JOURNAL   Mol. Cell. Biol. 31 (10), 1949-1958 (2011)
   PUBMED   21402781
  REMARK    GeneRIF: findings suggest that Suv39H1 and Suv39H2 are key
            hypoxia-induced methyltransferases; their decline in fetal lung
            during late gestation is critical for epigenetic changes resulting
            in the developmental induction of SP-A
REFERENCE   3  (bases 1 to 3093)
  AUTHORS   Sun,X.J., Xu,P.F., Zhou,T., Hu,M., Fu,C.T., Zhang,Y., Jin,Y.,
            Chen,Y., Chen,S.J., Huang,Q.H., Liu,T.X. and Chen,Z.
  TITLE     Genome-wide survey and developmental expression mapping of
            zebrafish SET domain-containing genes
  JOURNAL   PLoS ONE 3 (1), E1499 (2008)
   PUBMED   18231586
  REMARK    GeneRIF: The SUV39H2 gene is found in tetrapods (e.g., human, mouse
            and frog) but not in zebrafish, suggesting that this gene is
            generated by a tetrapod lineage-specific gene duplication event.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3093)
  AUTHORS   Wu,C., Ma,M.H., Brown,K.R., Geisler,M., Li,L., Tzeng,E., Jia,C.Y.,
            Jurisica,I. and Li,S.S.
  TITLE     Systematic identification of SH3 domain-mediated human
            protein-protein interactions by peptide array target screening
  JOURNAL   Proteomics 7 (11), 1775-1785 (2007)
   PUBMED   17474147
REFERENCE   5  (bases 1 to 3093)
  AUTHORS   Yoon,K.A., Hwangbo,B., Kim,I.J., Park,S., Kim,H.S., Kee,H.J.,
            Lee,J.E., Jang,Y.K., Park,J.G. and Lee,J.S.
  TITLE     Novel polymorphisms in the SUV39H2 histone methyltransferase and
            the risk of lung cancer
  JOURNAL   Carcinogenesis 27 (11), 2217-2222 (2006)
   PUBMED   16774942
  REMARK    GeneRIF: a novel SUV39H2 polymorphism may have a role in lung
            cancer susceptibility for smokers
            GeneRIF: Observational study of gene-disease association and
            gene-environment interaction. (HuGE Navigator)
REFERENCE   6  (bases 1 to 3093)
  AUTHORS   Frontelo,P., Leader,J.E., Yoo,N., Potocki,A.C., Crawford,M.,
            Kulik,M. and Lechleider,R.J.
  TITLE     Suv39h histone methyltransferases interact with Smads and cooperate
            in BMP-induced repression
  JOURNAL   Oncogene 23 (30), 5242-5251 (2004)
   PUBMED   15107829
REFERENCE   7  (bases 1 to 3093)
  AUTHORS   Deloukas,P., Earthrowl,M.E., Grafham,D.V., Rubenfield,M.,
            French,L., Steward,C.A., Sims,S.K., Jones,M.C., Searle,S.,
            Scott,C., Howe,K., Hunt,S.E., Andrews,T.D., Gilbert,J.G.,
            Swarbreck,D., Ashurst,J.L., Taylor,A., Battles,J., Bird,C.P.,
            Ainscough,R., Almeida,J.P., Ashwell,R.I., Ambrose,K.D.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Bates,K.,
            Beasley,H., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.C.,
            Burrill,W., Burton,J., Cahill,P., Camire,D., Carter,N.P.,
            Chapman,J.C., Clark,S.Y., Clarke,G., Clee,C.M., Clegg,S., Corby,N.,
            Coulson,A., Dhami,P., Dutta,I., Dunn,M., Faulkner,L., Frankish,A.,
            Frankland,J.A., Garner,P., Garnett,J., Gribble,S., Griffiths,C.,
            Grocock,R., Gustafson,E., Hammond,S., Harley,J.L., Hart,E.,
            Heath,P.D., Ho,T.P., Hopkins,B., Horne,J., Howden,P.J., Huckle,E.,
            Hynds,C., Johnson,C., Johnson,D., Kana,A., Kay,M., Kimberley,A.M.,
            Kershaw,J.K., Kokkinaki,M., Laird,G.K., Lawlor,S., Lee,H.M.,
            Leongamornlert,D.A., Laird,G., Lloyd,C., Lloyd,D.M., Loveland,J.,
            Lovell,J., McLaren,S., McLay,K.E., McMurray,A.,
            Mashreghi-Mohammadi,M., Matthews,L., Milne,S., Nickerson,T.,
            Nguyen,M., Overton-Larty,E., Palmer,S.A., Pearce,A.V., Peck,A.I.,
            Pelan,S., Phillimore,B., Porter,K., Rice,C.M., Rogosin,A.,
            Ross,M.T., Sarafidou,T., Sehra,H.K., Shownkeen,R., Skuce,C.D.,
            Smith,M., Standring,L., Sycamore,N., Tester,J., Thorpe,A.,
            Torcasso,W., Tracey,A., Tromans,A., Tsolas,J., Wall,M., Walsh,J.,
            Wang,H., Weinstock,K., West,A.P., Willey,D.L., Whitehead,S.L.,
            Wilming,L., Wray,P.W., Young,L., Chen,Y., Lovering,R.C.,
            Moschonas,N.K., Siebert,R., Fechtel,K., Bentley,D., Durbin,R.,
            Hubbard,T., Doucette-Stamm,L., Beck,S., Smith,D.R. and Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 10
  JOURNAL   Nature 429 (6990), 375-381 (2004)
   PUBMED   15164054
REFERENCE   8  (bases 1 to 3093)
  AUTHORS   Ait-Si-Ali,S., Guasconi,V., Fritsch,L., Yahi,H., Sekhri,R.,
            Naguibneva,I., Robin,P., Cabon,F., Polesskaya,A. and
            Harel-Bellan,A.
  TITLE     A Suv39h-dependent mechanism for silencing S-phase genes in
            differentiating but not in cycling cells
  JOURNAL   EMBO J. 23 (3), 605-615 (2004)
   PUBMED   14765126
REFERENCE   9  (bases 1 to 3093)
  AUTHORS   O'Carroll,D., Scherthan,H., Peters,A.H., Opravil,S., Haynes,A.R.,
            Laible,G., Rea,S., Schmid,M., Lebersorger,A., Jerratsch,M.,
            Sattler,L., Mattei,M.G., Denny,P., Brown,S.D., Schweizer,D. and
            Jenuwein,T.
  TITLE     Isolation and characterization of Suv39h2, a second histone H3
            methyltransferase gene that displays testis-specific expression
  JOURNAL   Mol. Cell. Biol. 20 (24), 9423-9433 (2000)
   PUBMED   11094092
REFERENCE   10 (bases 1 to 3093)
  AUTHORS   Rea,S., Eisenhaber,F., O'Carroll,D., Strahl,B.D., Sun,Z.W.,
            Schmid,M., Opravil,S., Mechtler,K., Ponting,C.P., Allis,C.D. and
            Jenuwein,T.
  TITLE     Regulation of chromatin structure by site-specific histone H3
            methyltransferases
  JOURNAL   Nature 406 (6796), 593-599 (2000)
   PUBMED   10949293
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC007754.2.
            On Aug 25, 2003 this sequence version replaced gi:20149682.
            
            Transcript Variant: This variant (3) contains an alternate 5'
            terminal exon, and is missing the subsequent exon compared to
            variant 1. This results in translation initiation from an in-frame,
            downstream AUG, and a shorter isoform (2) compared to isoform 1.
            Variants 2 and 3 encode the same isoform.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC007754.2 [ECO:0000332]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..3093
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10p13"
     gene            1..3093
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /note="suppressor of variegation 3-9 homolog 2
                     (Drosophila)"
                     /db_xref="GeneID:79723"
                     /db_xref="HGNC:17287"
                     /db_xref="HPRD:07580"
                     /db_xref="MIM:606503"
     exon            1..228
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    22..24
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /note="upstream in-frame stop codon"
     variation       31
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:374848659"
     variation       41
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:192886481"
     variation       45
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184647815"
     variation       109
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369551521"
     variation       122..123
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:145358833"
     exon            229..900
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /inference="alignment:Splign:1.39.8"
     CDS             232..1284
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /EC_number="2.1.1.43"
                     /note="isoform 2 is encoded by transcript variant 3;
                     histone-lysine N-methyltransferase SUV39H2; H3-K9-HMTase
                     2; su(var)3-9 homolog 2; lysine N-methyltransferase 1B;
                     histone H3-K9 methyltransferase 2"
                     /codon_start=1
                     /product="histone-lysine N-methyltransferase SUV39H2
                     isoform 2"
                     /protein_id="NP_078946.1"
                     /db_xref="GI:13375930"
                     /db_xref="CCDS:CCDS7104.1"
                     /db_xref="GeneID:79723"
                     /db_xref="HGNC:17287"
                     /db_xref="HPRD:07580"
                     /db_xref="MIM:606503"
                     /translation="
MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQQFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQKCCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN
"
     misc_feature    <235..330
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /note="Chromatin organization modifier (chromo) domain is
                     a conserved region of around 50 amino acids found in a
                     variety of chromosomal proteins, which appear to play a
                     role in the functional organization of the eukaryotic
                     nucleus. Experimental evidence...; Region: CHROMO;
                     cd00024"
                     /db_xref="CDD:28908"
     misc_feature    order(247..249,253..255,262..264,274..276,286..288,
                     298..303)
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /note="histone binding site; other site"
                     /db_xref="CDD:28908"
     misc_feature    484..777
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /note="Pre-SET motif; Region: Pre-SET; pfam05033"
                     /db_xref="CDD:203156"
     misc_feature    799..1170
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /note="SET (Su(var)3-9, Enhancer-of-zeste, Trithorax)
                     domain; Region: SET; smart00317"
                     /db_xref="CDD:197649"
     variation       318
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148153307"
     variation       339
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376764262"
     variation       341
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140852434"
     variation       395
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144521316"
     variation       399
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3740112"
     variation       413..414
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:35348245"
     variation       418
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372163934"
     variation       430
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201043867"
     variation       443
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:138508980"
     variation       451
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:45473500"
     variation       459
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150726093"
     STS             532..1031
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /standard_name="MARC_27758-27759:1034860367:1"
                     /db_xref="UniSTS:269123"
     STS             543..866
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /standard_name="ksks283"
                     /db_xref="UniSTS:514323"
     variation       570
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138078553"
     variation       596
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:149546848"
     variation       606
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200539708"
     variation       613
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:376480219"
     variation       804
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368991744"
     variation       832
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375736366"
     variation       834
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199654065"
     variation       870
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144034230"
     exon            901..1047
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /inference="alignment:Splign:1.39.8"
     variation       960
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:190174096"
     variation       972
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:183140822"
     variation       973
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148667087"
     variation       1017
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:17353856"
     variation       1023
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369186882"
     variation       1038
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147278353"
     exon            1048..1177
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /inference="alignment:Splign:1.39.8"
     variation       1092
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:61730323"
     variation       1117
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369793867"
     exon            1178..3087
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /inference="alignment:Splign:1.39.8"
     variation       1253
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199727444"
     variation       1263
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:144605484"
     variation       1279
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201395473"
     variation       1303
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:375126181"
     variation       1339
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368830300"
     variation       1375
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113301024"
     variation       1396
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373511332"
     variation       1411
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:11547181"
     variation       1432
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373567048"
     variation       1443
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:180989547"
     variation       1447
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:375028927"
     STS             1566..1687
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /standard_name="RH48597"
                     /db_xref="UniSTS:71892"
     variation       1624
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:116910335"
     variation       1637
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:75420442"
     polyA_signal    1799..1804
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
     variation       1818..1820
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace=""
                     /replace="aat"
                     /db_xref="dbSNP:367684066"
     polyA_site      1819
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
     polyA_site      1835
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
     polyA_signal    1844..1849
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
     variation       1856..1859
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace=""
                     /replace="aatt"
                     /db_xref="dbSNP:371874353"
     polyA_site      1861
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
     polyA_site      1872
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
     variation       1969
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142967205"
     variation       2026
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:185218421"
     variation       2088
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:41284455"
     variation       2179
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11594111"
     variation       2250
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:190438184"
     variation       2366
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181251834"
     variation       2504
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:61843036"
     variation       2641
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:75516757"
     variation       2663
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376829730"
     variation       2721
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150828159"
     variation       2846
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:139176971"
     variation       2910
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11259385"
     STS             2949..3031
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /standard_name="L18426"
                     /db_xref="UniSTS:34648"
     STS             2950..3029
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /standard_name="D5S1597E"
                     /db_xref="UniSTS:151019"
     STS             2951..3053
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /standard_name="D11S2921"
                     /db_xref="UniSTS:152074"
     STS             2953..3022
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /standard_name="D1S1423"
                     /db_xref="UniSTS:149619"
     variation       2990
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:186353154"
     variation       3008
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191603474"
     variation       3009
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371491790"
     variation       3028
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:183557434"
     variation       3076
                     /gene="SUV39H2"
                     /gene_synonym="KMT1B"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:79193913"
ORIGIN      
cggggccgaggcgcgaggaggtgaggctggagcgcggccccctcgccttccctgttcccaggcaagctcccaaggcccgggcggcggggccgtcccgcgggccagccagatggcgacgtggcggttccccgcccgccgcgaccccaactccgggacgcacgctgcggacgcctatcctcccccaggccgctgacccgcctccctgcccggccggctcccgccgcggaggatatggaatattatcttgtaaaatggaaaggatggccagattctacaaatacttgggaacctttgcaaaatctgaagtgcccgttactgcttcagcaattctctaatgacaagcataattatttatctcaggtaaagaaaggcaaagcaataactccaaaagacaataacaaaactttgaaacctgccattgctgagtacattgtgaagaaggctaaacaaaggatagctctgcagagatggcaagatgaactcaacagaagaaagaatcataaaggaatgatatttgttgaaaatactgttgatttagagggcccaccttcagacttctattacattaacgaatacaaaccagctcctggaatcagcttagtcaatgaagctacctttggttgttcatgcacagattgcttctttcaaaaatgttgtcctgctgaagctggagttcttttggcttataataaaaaccaacaaattaaaatcccacctggtactcccatctatgaatgcaactcaaggtgtcagtgtggtcctgattgtcccaataggattgtacaaaaaggcacacagtattcgctttgcatctttcgaactagcaatggacgtggctggggtgtaaagacccttgtgaagattaaaagaatgagttttgtcatggaatatgttggagaggtaatcacaagtgaagaagctgaaagacgaggacagttctatgacaacaagggaatcacgtatctctttgatctggactatgagtctgatgaattcacagtggatgcggctcgatacggcaatgtgtctcattttgtgaatcacagctgtgacccaaatcttcaggtgttcaatgttttcattgataacctcgatactcgtcttccccgaatagcattgttttccacaagaaccataaatgctggagaagagctgacttttgattatcaaatgaaaggttctggagatatatcttcagattctattgaccacagcccagccaaaaagagggtcagaacagtatgtaaatgtggagctgtgacttgcagaggttacctcaactgaactttttcaggaaatagagctgatgattataatatttttttcctaatgttaacatttttaaaaatacatatttgggactcttattatcaaggttctacctatgttaatttacaattcatgtttcaagacatttgccaaatgtattaccgatgcctctgaaaagggggtcactgggtctcatagactgatatgaagtcgacatatttatagtgcttagagaccaaactaatggaaggcagactatttacagcttagtatatgtgtacttaagtctatgtgaacagagaaatgcctcccgtagtgtttgaaagcgttaagctgataatgtaattaacaactgctgagagatcaaagattcaacttgccatacacctcaaattcggagaaacagttaatttgggcaaatctacagttctgtttttgctactctattgtcattcctgtttaatactcactgtacttgtatttgagacaaataggtgatactgaattttatactgttttctacttttccattaaaacattggcacctcaatgataaagaaatttaaggtataaaattaaatgtaaaaattaatttcagcttcatttcgtatttcgaagcaatctagactgttgtgatgagtgtatgtctgaacctgtaattcttaaaagacttcttaatcttctagaagaaaaatctccgaagagctctctctagaagtccaaaatggctagccattatgcttctttgaaaggacatgataatgggaccaggatggttttttggagtaccaagcaaggggaatggagcactttaagggcgcctgttagtaacatgaattggaaatctgtgtcgagtacctctgatctaaacggtaaaacaagctgcctggagagcagctgtacctaacaatactgtaatgtacattaacattacagcctctcaatttcaggcaggtgtaacagttcctttccaccagatttaatatttttatacttcctgcaggttcttcttaaaaagtaatctatatttttgaactgatacttgttttatacataaattttttttagatgtgataaagctaaacttggccaaagtgtgtgcctgaattattagacctttttattagtcaacctacgaagactaaaatagaatatattagttttcaagggagtgggaggcttccaacatagtattgaatctcaggaaaaactattctttcatgtctgattctgagatttctaattgtgttgtgaaaatgataaatgcagcaaatctagctttcagtattcctaatttttacctaagctcattgctccaggctttgattacctaaaataagcttggataaaattgaaccaacttcaagaatgcagcacttcttaatctttagctctttcttgggagaagctagactttattcattatattgctatgacaacttcactctttcataatatataggataaattgtttacatgattggaccctcagattctgttaaccaaaattgcagaatggggggccaggcctgtgtggtggctcacacctgtgatcccagcactttgggaggctgaggtaggaggatcacgtgaggtcgggagttcaagaccagcctggccatcatggtgaaaccctgtctctactgaaaatacaaaaattagccgggcgtggtggcacacgcctgtagtcccagctactcaggaggctgaggcaggagaatcacttgaattcaggaggcggaggttgcagtgagccaagatcataccactgcactgcagcctgagtgacacagtaagactgtctccaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:79723 -> Molecular function: GO:0003682 [chromatin binding] evidence: IEA
            GeneID:79723 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:79723 -> Molecular function: GO:0008270 [zinc ion binding] evidence: IEA
            GeneID:79723 -> Molecular function: GO:0046974 [histone methyltransferase activity (H3-K9 specific)] evidence: IDA
            GeneID:79723 -> Biological process: GO:0006333 [chromatin assembly or disassembly] evidence: IMP
            GeneID:79723 -> Biological process: GO:0006338 [chromatin remodeling] evidence: IDA
            GeneID:79723 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
            GeneID:79723 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: IEA
            GeneID:79723 -> Biological process: GO:0007140 [male meiosis] evidence: IEA
            GeneID:79723 -> Biological process: GO:0030154 [cell differentiation] evidence: IEA
            GeneID:79723 -> Cellular component: GO:0000775 [chromosome, centromeric region] evidence: IEA
            GeneID:79723 -> Cellular component: GO:0000785 [chromatin] evidence: IDA
            GeneID:79723 -> Cellular component: GO:0005720 [nuclear heterochromatin] evidence: IEA
ANNOTATIONS from NCBI Entrez Gene (20130726):
            NP_078946 -> EC 2.1.1.43

by @meso_cacase at DBCLS
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