2024-03-29 17:41:58, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_024670 3093 bp mRNA linear PRI 18-APR-2013 DEFINITION Homo sapiens suppressor of variegation 3-9 homolog 2 (Drosophila) (SUV39H2), transcript variant 3, mRNA. ACCESSION NM_024670 VERSION NM_024670.3 GI:34147611 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 3093) AUTHORS Syreeni,A., El-Osta,A., Forsblom,C., Sandholm,N., Parkkonen,M., Tarnow,L., Parving,H.H., McKnight,A.J., Maxwell,A.P., Cooper,M.E. and Groop,P.H. CONSRTM FinnDiane Study Group TITLE Genetic examination of SETD7 and SUV39H1/H2 methyltransferases and the risk of diabetes complications in patients with type 1 diabetes JOURNAL Diabetes 60 (11), 3073-3080 (2011) PUBMED 21896933 REMARK GeneRIF: genetic association studies in a Finnish population with type I diabetes: The minor T allele of exonic SNP rs17353856 in SUV39H2 is associated with diabetic retinopathy (in a larger meta-analysis); thus an genetic variation may be protective. REFERENCE 2 (bases 1 to 3093) AUTHORS Benlhabib,H. and Mendelson,C.R. TITLE Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia JOURNAL Mol. Cell. Biol. 31 (10), 1949-1958 (2011) PUBMED 21402781 REMARK GeneRIF: findings suggest that Suv39H1 and Suv39H2 are key hypoxia-induced methyltransferases; their decline in fetal lung during late gestation is critical for epigenetic changes resulting in the developmental induction of SP-A REFERENCE 3 (bases 1 to 3093) AUTHORS Sun,X.J., Xu,P.F., Zhou,T., Hu,M., Fu,C.T., Zhang,Y., Jin,Y., Chen,Y., Chen,S.J., Huang,Q.H., Liu,T.X. and Chen,Z. TITLE Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genes JOURNAL PLoS ONE 3 (1), E1499 (2008) PUBMED 18231586 REMARK GeneRIF: The SUV39H2 gene is found in tetrapods (e.g., human, mouse and frog) but not in zebrafish, suggesting that this gene is generated by a tetrapod lineage-specific gene duplication event. Publication Status: Online-Only REFERENCE 4 (bases 1 to 3093) AUTHORS Wu,C., Ma,M.H., Brown,K.R., Geisler,M., Li,L., Tzeng,E., Jia,C.Y., Jurisica,I. and Li,S.S. TITLE Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening JOURNAL Proteomics 7 (11), 1775-1785 (2007) PUBMED 17474147 REFERENCE 5 (bases 1 to 3093) AUTHORS Yoon,K.A., Hwangbo,B., Kim,I.J., Park,S., Kim,H.S., Kee,H.J., Lee,J.E., Jang,Y.K., Park,J.G. and Lee,J.S. TITLE Novel polymorphisms in the SUV39H2 histone methyltransferase and the risk of lung cancer JOURNAL Carcinogenesis 27 (11), 2217-2222 (2006) PUBMED 16774942 REMARK GeneRIF: a novel SUV39H2 polymorphism may have a role in lung cancer susceptibility for smokers GeneRIF: Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) REFERENCE 6 (bases 1 to 3093) AUTHORS Frontelo,P., Leader,J.E., Yoo,N., Potocki,A.C., Crawford,M., Kulik,M. and Lechleider,R.J. TITLE Suv39h histone methyltransferases interact with Smads and cooperate in BMP-induced repression JOURNAL Oncogene 23 (30), 5242-5251 (2004) PUBMED 15107829 REFERENCE 7 (bases 1 to 3093) AUTHORS Deloukas,P., Earthrowl,M.E., Grafham,D.V., Rubenfield,M., French,L., Steward,C.A., Sims,S.K., Jones,M.C., Searle,S., Scott,C., Howe,K., Hunt,S.E., Andrews,T.D., Gilbert,J.G., Swarbreck,D., Ashurst,J.L., Taylor,A., Battles,J., Bird,C.P., Ainscough,R., Almeida,J.P., Ashwell,R.I., Ambrose,K.D., Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Bates,K., Beasley,H., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Cahill,P., Camire,D., Carter,N.P., Chapman,J.C., Clark,S.Y., Clarke,G., Clee,C.M., Clegg,S., Corby,N., Coulson,A., Dhami,P., Dutta,I., Dunn,M., Faulkner,L., Frankish,A., Frankland,J.A., Garner,P., Garnett,J., Gribble,S., Griffiths,C., Grocock,R., Gustafson,E., Hammond,S., Harley,J.L., Hart,E., Heath,P.D., Ho,T.P., Hopkins,B., Horne,J., Howden,P.J., Huckle,E., Hynds,C., Johnson,C., Johnson,D., Kana,A., Kay,M., Kimberley,A.M., Kershaw,J.K., Kokkinaki,M., Laird,G.K., Lawlor,S., Lee,H.M., Leongamornlert,D.A., Laird,G., Lloyd,C., Lloyd,D.M., Loveland,J., Lovell,J., McLaren,S., McLay,K.E., McMurray,A., Mashreghi-Mohammadi,M., Matthews,L., Milne,S., Nickerson,T., Nguyen,M., Overton-Larty,E., Palmer,S.A., Pearce,A.V., Peck,A.I., Pelan,S., Phillimore,B., Porter,K., Rice,C.M., Rogosin,A., Ross,M.T., Sarafidou,T., Sehra,H.K., Shownkeen,R., Skuce,C.D., Smith,M., Standring,L., Sycamore,N., Tester,J., Thorpe,A., Torcasso,W., Tracey,A., Tromans,A., Tsolas,J., Wall,M., Walsh,J., Wang,H., Weinstock,K., West,A.P., Willey,D.L., Whitehead,S.L., Wilming,L., Wray,P.W., Young,L., Chen,Y., Lovering,R.C., Moschonas,N.K., Siebert,R., Fechtel,K., Bentley,D., Durbin,R., Hubbard,T., Doucette-Stamm,L., Beck,S., Smith,D.R. and Rogers,J. TITLE The DNA sequence and comparative analysis of human chromosome 10 JOURNAL Nature 429 (6990), 375-381 (2004) PUBMED 15164054 REFERENCE 8 (bases 1 to 3093) AUTHORS Ait-Si-Ali,S., Guasconi,V., Fritsch,L., Yahi,H., Sekhri,R., Naguibneva,I., Robin,P., Cabon,F., Polesskaya,A. and Harel-Bellan,A. TITLE A Suv39h-dependent mechanism for silencing S-phase genes in differentiating but not in cycling cells JOURNAL EMBO J. 23 (3), 605-615 (2004) PUBMED 14765126 REFERENCE 9 (bases 1 to 3093) AUTHORS O'Carroll,D., Scherthan,H., Peters,A.H., Opravil,S., Haynes,A.R., Laible,G., Rea,S., Schmid,M., Lebersorger,A., Jerratsch,M., Sattler,L., Mattei,M.G., Denny,P., Brown,S.D., Schweizer,D. and Jenuwein,T. TITLE Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression JOURNAL Mol. Cell. Biol. 20 (24), 9423-9433 (2000) PUBMED 11094092 REFERENCE 10 (bases 1 to 3093) AUTHORS Rea,S., Eisenhaber,F., O'Carroll,D., Strahl,B.D., Sun,Z.W., Schmid,M., Opravil,S., Mechtler,K., Ponting,C.P., Allis,C.D. and Jenuwein,T. TITLE Regulation of chromatin structure by site-specific histone H3 methyltransferases JOURNAL Nature 406 (6796), 593-599 (2000) PUBMED 10949293 COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC007754.2. On Aug 25, 2003 this sequence version replaced gi:20149682. Transcript Variant: This variant (3) contains an alternate 5' terminal exon, and is missing the subsequent exon compared to variant 1. This results in translation initiation from an in-frame, downstream AUG, and a shorter isoform (2) compared to isoform 1. Variants 2 and 3 encode the same isoform. ##Evidence-Data-START## Transcript exon combination :: BC007754.2 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. FEATURES Location/Qualifiers source 1..3093 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="10" /map="10p13" gene 1..3093 /gene="SUV39H2" /gene_synonym="KMT1B" /note="suppressor of variegation 3-9 homolog 2 (Drosophila)" /db_xref="GeneID:79723" /db_xref="HGNC:17287" /db_xref="HPRD:07580" /db_xref="MIM:606503" exon 1..228 /gene="SUV39H2" /gene_synonym="KMT1B" /inference="alignment:Splign:1.39.8" misc_feature 22..24 /gene="SUV39H2" /gene_synonym="KMT1B" /note="upstream in-frame stop codon" variation 31 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="c" /db_xref="dbSNP:374848659" variation 41 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:192886481" variation 45 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:184647815" variation 109 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:369551521" variation 122..123 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="" /replace="g" /db_xref="dbSNP:145358833" exon 229..900 /gene="SUV39H2" /gene_synonym="KMT1B" /inference="alignment:Splign:1.39.8" CDS 232..1284 /gene="SUV39H2" /gene_synonym="KMT1B" /EC_number="2.1.1.43" /note="isoform 2 is encoded by transcript variant 3; histone-lysine N-methyltransferase SUV39H2; H3-K9-HMTase 2; su(var)3-9 homolog 2; lysine N-methyltransferase 1B; histone H3-K9 methyltransferase 2" /codon_start=1 /product="histone-lysine N-methyltransferase SUV39H2 isoform 2" /protein_id="NP_078946.1" /db_xref="GI:13375930" /db_xref="CCDS:CCDS7104.1" /db_xref="GeneID:79723" /db_xref="HGNC:17287" /db_xref="HPRD:07580" /db_xref="MIM:606503" /translation="
MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQQFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQKCCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN
" misc_feature <235..330 /gene="SUV39H2" /gene_synonym="KMT1B" /note="Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; Region: CHROMO; cd00024" /db_xref="CDD:28908" misc_feature order(247..249,253..255,262..264,274..276,286..288, 298..303) /gene="SUV39H2" /gene_synonym="KMT1B" /note="histone binding site; other site" /db_xref="CDD:28908" misc_feature 484..777 /gene="SUV39H2" /gene_synonym="KMT1B" /note="Pre-SET motif; Region: Pre-SET; pfam05033" /db_xref="CDD:203156" misc_feature 799..1170 /gene="SUV39H2" /gene_synonym="KMT1B" /note="SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; Region: SET; smart00317" /db_xref="CDD:197649" variation 318 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:148153307" variation 339 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:376764262" variation 341 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:140852434" variation 395 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:144521316" variation 399 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:3740112" variation 413..414 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="" /replace="c" /db_xref="dbSNP:35348245" variation 418 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:372163934" variation 430 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:201043867" variation 443 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:138508980" variation 451 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="c" /db_xref="dbSNP:45473500" variation 459 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:150726093" STS 532..1031 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="MARC_27758-27759:1034860367:1" /db_xref="UniSTS:269123" STS 543..866 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="ksks283" /db_xref="UniSTS:514323" variation 570 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:138078553" variation 596 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:149546848" variation 606 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:200539708" variation 613 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="c" /db_xref="dbSNP:376480219" variation 804 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:368991744" variation 832 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:375736366" variation 834 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:199654065" variation 870 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:144034230" exon 901..1047 /gene="SUV39H2" /gene_synonym="KMT1B" /inference="alignment:Splign:1.39.8" variation 960 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:190174096" variation 972 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:183140822" variation 973 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:148667087" variation 1017 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:17353856" variation 1023 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:369186882" variation 1038 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:147278353" exon 1048..1177 /gene="SUV39H2" /gene_synonym="KMT1B" /inference="alignment:Splign:1.39.8" variation 1092 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:61730323" variation 1117 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:369793867" exon 1178..3087 /gene="SUV39H2" /gene_synonym="KMT1B" /inference="alignment:Splign:1.39.8" variation 1253 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:199727444" variation 1263 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:144605484" variation 1279 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:201395473" variation 1303 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:375126181" variation 1339 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:368830300" variation 1375 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:113301024" variation 1396 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:373511332" variation 1411 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="c" /db_xref="dbSNP:11547181" variation 1432 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:373567048" variation 1443 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="c" /db_xref="dbSNP:180989547" variation 1447 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="" /replace="g" /db_xref="dbSNP:375028927" STS 1566..1687 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="RH48597" /db_xref="UniSTS:71892" variation 1624 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:116910335" variation 1637 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="c" /db_xref="dbSNP:75420442" polyA_signal 1799..1804 /gene="SUV39H2" /gene_synonym="KMT1B" variation 1818..1820 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="" /replace="aat" /db_xref="dbSNP:367684066" polyA_site 1819 /gene="SUV39H2" /gene_synonym="KMT1B" polyA_site 1835 /gene="SUV39H2" /gene_synonym="KMT1B" polyA_signal 1844..1849 /gene="SUV39H2" /gene_synonym="KMT1B" variation 1856..1859 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="" /replace="aatt" /db_xref="dbSNP:371874353" polyA_site 1861 /gene="SUV39H2" /gene_synonym="KMT1B" polyA_site 1872 /gene="SUV39H2" /gene_synonym="KMT1B" variation 1969 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:142967205" variation 2026 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:185218421" variation 2088 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:41284455" variation 2179 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:11594111" variation 2250 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:190438184" variation 2366 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:181251834" variation 2504 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:61843036" variation 2641 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:75516757" variation 2663 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:376829730" variation 2721 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:150828159" variation 2846 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:139176971" variation 2910 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:11259385" STS 2949..3031 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="L18426" /db_xref="UniSTS:34648" STS 2950..3029 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="D5S1597E" /db_xref="UniSTS:151019" STS 2951..3053 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="D11S2921" /db_xref="UniSTS:152074" STS 2953..3022 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="D1S1423" /db_xref="UniSTS:149619" variation 2990 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:186353154" variation 3008 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:191603474" variation 3009 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:371491790" variation 3028 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:183557434" variation 3076 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="t" /db_xref="dbSNP:79193913" ORIGIN
cggggccgaggcgcgaggaggtgaggctggagcgcggccccctcgccttccctgttcccaggcaagctcccaaggcccgggcggcggggccgtcccgcgggccagccagatggcgacgtggcggttccccgcccgccgcgaccccaactccgggacgcacgctgcggacgcctatcctcccccaggccgctgacccgcctccctgcccggccggctcccgccgcggaggatatggaatattatcttgtaaaatggaaaggatggccagattctacaaatacttgggaacctttgcaaaatctgaagtgcccgttactgcttcagcaattctctaatgacaagcataattatttatctcaggtaaagaaaggcaaagcaataactccaaaagacaataacaaaactttgaaacctgccattgctgagtacattgtgaagaaggctaaacaaaggatagctctgcagagatggcaagatgaactcaacagaagaaagaatcataaaggaatgatatttgttgaaaatactgttgatttagagggcccaccttcagacttctattacattaacgaatacaaaccagctcctggaatcagcttagtcaatgaagctacctttggttgttcatgcacagattgcttctttcaaaaatgttgtcctgctgaagctggagttcttttggcttataataaaaaccaacaaattaaaatcccacctggtactcccatctatgaatgcaactcaaggtgtcagtgtggtcctgattgtcccaataggattgtacaaaaaggcacacagtattcgctttgcatctttcgaactagcaatggacgtggctggggtgtaaagacccttgtgaagattaaaagaatgagttttgtcatggaatatgttggagaggtaatcacaagtgaagaagctgaaagacgaggacagttctatgacaacaagggaatcacgtatctctttgatctggactatgagtctgatgaattcacagtggatgcggctcgatacggcaatgtgtctcattttgtgaatcacagctgtgacccaaatcttcaggtgttcaatgttttcattgataacctcgatactcgtcttccccgaatagcattgttttccacaagaaccataaatgctggagaagagctgacttttgattatcaaatgaaaggttctggagatatatcttcagattctattgaccacagcccagccaaaaagagggtcagaacagtatgtaaatgtggagctgtgacttgcagaggttacctcaactgaactttttcaggaaatagagctgatgattataatatttttttcctaatgttaacatttttaaaaatacatatttgggactcttattatcaaggttctacctatgttaatttacaattcatgtttcaagacatttgccaaatgtattaccgatgcctctgaaaagggggtcactgggtctcatagactgatatgaagtcgacatatttatagtgcttagagaccaaactaatggaaggcagactatttacagcttagtatatgtgtacttaagtctatgtgaacagagaaatgcctcccgtagtgtttgaaagcgttaagctgataatgtaattaacaactgctgagagatcaaagattcaacttgccatacacctcaaattcggagaaacagttaatttgggcaaatctacagttctgtttttgctactctattgtcattcctgtttaatactcactgtacttgtatttgagacaaataggtgatactgaattttatactgttttctacttttccattaaaacattggcacctcaatgataaagaaatttaaggtataaaattaaatgtaaaaattaatttcagcttcatttcgtatttcgaagcaatctagactgttgtgatgagtgtatgtctgaacctgtaattcttaaaagacttcttaatcttctagaagaaaaatctccgaagagctctctctagaagtccaaaatggctagccattatgcttctttgaaaggacatgataatgggaccaggatggttttttggagtaccaagcaaggggaatggagcactttaagggcgcctgttagtaacatgaattggaaatctgtgtcgagtacctctgatctaaacggtaaaacaagctgcctggagagcagctgtacctaacaatactgtaatgtacattaacattacagcctctcaatttcaggcaggtgtaacagttcctttccaccagatttaatatttttatacttcctgcaggttcttcttaaaaagtaatctatatttttgaactgatacttgttttatacataaattttttttagatgtgataaagctaaacttggccaaagtgtgtgcctgaattattagacctttttattagtcaacctacgaagactaaaatagaatatattagttttcaagggagtgggaggcttccaacatagtattgaatctcaggaaaaactattctttcatgtctgattctgagatttctaattgtgttgtgaaaatgataaatgcagcaaatctagctttcagtattcctaatttttacctaagctcattgctccaggctttgattacctaaaataagcttggataaaattgaaccaacttcaagaatgcagcacttcttaatctttagctctttcttgggagaagctagactttattcattatattgctatgacaacttcactctttcataatatataggataaattgtttacatgattggaccctcagattctgttaaccaaaattgcagaatggggggccaggcctgtgtggtggctcacacctgtgatcccagcactttgggaggctgaggtaggaggatcacgtgaggtcgggagttcaagaccagcctggccatcatggtgaaaccctgtctctactgaaaatacaaaaattagccgggcgtggtggcacacgcctgtagtcccagctactcaggaggctgaggcaggagaatcacttgaattcaggaggcggaggttgcagtgagccaagatcataccactgcactgcagcctgagtgacacagtaagactgtctccaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726): GeneID:79723 -> Molecular function: GO:0003682 [chromatin binding] evidence: IEA GeneID:79723 -> Molecular function: GO:0005515 [protein binding] evidence: IPI GeneID:79723 -> Molecular function: GO:0008270 [zinc ion binding] evidence: IEA GeneID:79723 -> Molecular function: GO:0046974 [histone methyltransferase activity (H3-K9 specific)] evidence: IDA GeneID:79723 -> Biological process: GO:0006333 [chromatin assembly or disassembly] evidence: IMP GeneID:79723 -> Biological process: GO:0006338 [chromatin remodeling] evidence: IDA GeneID:79723 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA GeneID:79723 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: IEA GeneID:79723 -> Biological process: GO:0007140 [male meiosis] evidence: IEA GeneID:79723 -> Biological process: GO:0030154 [cell differentiation] evidence: IEA GeneID:79723 -> Cellular component: GO:0000775 [chromosome, centromeric region] evidence: IEA GeneID:79723 -> Cellular component: GO:0000785 [chromatin] evidence: IDA GeneID:79723 -> Cellular component: GO:0005720 [nuclear heterochromatin] evidence: IEA ANNOTATIONS from NCBI Entrez Gene (20130726): NP_078946 -> EC 2.1.1.43
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