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2024-04-19 01:52:46, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_024503 12408 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens human immunodeficiency virus type I enhancer binding
protein 3 (HIVEP3), transcript variant 1, mRNA.
ACCESSION NM_024503
VERSION NM_024503.4 GI:347582597
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 12408)
AUTHORS Young,N.A., Friedman,A.K., Kaffenberger,B., Rajaram,M.V.,
Birmingham,D.J., Rovin,B.H., Hebert,L.A., Schlesinger,L.S., Wu,L.C.
and Jarjour,W.N.
TITLE Novel estrogen target gene ZAS3 is overexpressed in systemic lupus
erythematosus
JOURNAL Mol. Immunol. 54 (1), 23-31 (2013)
PUBMED 23178823
REMARK GeneRIF: ZAS3 expression is directly regulated by estrogen and is
overexpressed in lupus. Its upregulation by estrogen could play a
critical role in female-biased autoimmune disorders.
REFERENCE 2 (bases 1 to 12408)
AUTHORS Shin,D.H., Park,K.W., Wu,L.C. and Hong,J.W.
TITLE ZAS3 promotes TNFalpha-induced apoptosis by blocking
NFvarkappaB-activated expression of the anti-apoptotic genes TRAF1
and TRAF2
JOURNAL BMB Rep 44 (4), 267-272 (2011)
PUBMED 21524353
REMARK GeneRIF: The inhibitory effect of ZAS3 on NF-kappa B activity is
mediated by neither direct association with N-kappa B nor
disrupting nuclear localization of NFvarkappaB.
REFERENCE 3 (bases 1 to 12408)
AUTHORS Yakovich,A.J., Jiang,B., Allen,C.E., Du,J., Wu,L.C. and
Barnard,J.A.
TITLE ZAS3 accentuates transforming growth factor beta signaling in
epithelial cells
JOURNAL Cell. Signal. 23 (1), 105-113 (2011)
PUBMED 20732416
REMARK GeneRIF: An interaction between ZAS3 and Smad proteins enhances
transforming growth factor beta signaling.
REFERENCE 4 (bases 1 to 12408)
AUTHORS Hong,J.W. and Wu,L.C.
TITLE ZAS3 represses NFkappaB-dependent transcription by direct
competition for DNA binding
JOURNAL BMB Rep 43 (12), 807-812 (2010)
PUBMED 21189157
REMARK GeneRIF: DNA competition by ZAS3 is sufficient to repress
transcription activated by NF-kappaB and that ZAS3 is an endogenous
kappaB-motif competitor with ininsic repression activity.
REFERENCE 5 (bases 1 to 12408)
AUTHORS Li,Y.J., Deng,J., Mayhew,G.M., Grimsley,J.W., Huo,X. and Vance,J.M.
TITLE Investigation of the PARK10 gene in Parkinson disease
JOURNAL Ann. Hum. Genet. 71 (PT 5), 639-647 (2007)
PUBMED 17388942
REMARK GeneRIF: Single nucleotide polymorphisms strongly support HIVEP3 as
a candidate for PARK10 in Parkinson disease.
GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 6 (bases 1 to 12408)
AUTHORS Qin,H., Wang,J., Liang,Y., Taniguchi,Y., Tanigaki,K. and Han,H.
TITLE RING1 inhibits transactivation of RBP-J by Notch through
interaction with LIM protein KyoT2
JOURNAL Nucleic Acids Res. 32 (4), 1492-1501 (2004)
PUBMED 14999091
REMARK Publication Status: Online-Only
REFERENCE 7 (bases 1 to 12408)
AUTHORS Oukka,M., Wein,M.N. and Glimcher,L.H.
TITLE Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in
T cells
JOURNAL J. Exp. Med. 199 (1), 15-24 (2004)
PUBMED 14707112
REMARK GeneRIF: Overexpression of KRC in transformed and primary T cells
leads to increased IL-2 production.
REFERENCE 8 (bases 1 to 12408)
AUTHORS Oukka,M., Kim,S.T., Lugo,G., Sun,J., Wu,L.C. and Glimcher,L.H.
TITLE A mammalian homolog of Drosophila schnurri, KRC, regulates TNF
receptor-driven responses and interacts with TRAF2
JOURNAL Mol. Cell 9 (1), 121-131 (2002)
PUBMED 11804591
REFERENCE 9 (bases 1 to 12408)
AUTHORS Hicar,M.D., Liu,Y., Allen,C.E. and Wu,L.C.
TITLE Structure of the human zinc finger protein HIVEP3: molecular
cloning, expression, exon-intron structure, and comparison with
paralogous genes HIVEP1 and HIVEP2
JOURNAL Genomics 71 (1), 89-100 (2001)
PUBMED 11161801
REFERENCE 10 (bases 1 to 12408)
AUTHORS Rustgi,A.K., Van 't Veer,L.J. and Bernards,R.
TITLE Two genes encode factors with NF-kappa B- and H2TF1-like
DNA-binding properties
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87 (22), 8707-8710 (1990)
PUBMED 2247438
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BC152563.1, AF278765.1,
AL445933.32 and AI082114.1.
This sequence is a reference standard in the RefSeqGene project.
On Sep 23, 2011 this sequence version replaced gi:189181748.
Summary: This gene encodes a member of the human immunodeficiency
virus type 1 enhancer-binding protein family. Members of this
protein family contain multiple zinc finger and acid-rich (ZAS)
domains and serine-threonine rich regions. This protein acts as a
transcription factor and is able to regulate nuclear factor
kappaB-mediated transcription by binding the kappaB motif in target
genes. This protein also binds the recombination signal sequence
that flanks the V, D, and J regions of immunoglobulin and T-cell
receptors. Alternate splicing results in both coding and non-coding
transcript variants. [provided by RefSeq, Sep 2011].
Transcript Variant: This variant (1) represents the longest
transcript and encodes the longer isoform (1).
Sequence Note: The RefSeq transcript and protein were derived from
genomic sequence to make the sequence consistent with the reference
genome assembly. The genomic coordinates used for the transcript
record were based on alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AF278765.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025084 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-217 BC152563.1 1-217
218-777 AF278765.1 11-570
778-5666 AL445933.32 145623-150511 c
5667-6830 AF278765.1 5460-6623
6831-7421 AL445933.32 78291-78881 c
7422-7908 AF278765.1 7215-7701
7909-12031 AL445933.32 72132-76254 c
12032-12408 AI082114.1 1-377 c
FEATURES Location/Qualifiers
source 1..12408
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p34"
gene 1..12408
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/note="human immunodeficiency virus type I enhancer
binding protein 3"
/db_xref="GeneID:59269"
/db_xref="HGNC:13561"
/db_xref="MIM:606649"
exon 1..295
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/inference="alignment:Splign:1.39.8"
exon 296..375
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/inference="alignment:Splign:1.39.8"
exon 376..574
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/inference="alignment:Splign:1.39.8"
exon 575..6156
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/inference="alignment:Splign:1.39.8"
variation 749
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="g"
/replace="t"
/db_xref="dbSNP:201869082"
misc_feature 1066..1068
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/note="upstream in-frame stop codon"
CDS 1096..8316
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/note="isoform a is encoded by transcript variant 1;
transcription factor HIVEP3; kappa-binding protein 1; zinc
finger protein ZAS3; kappa-B and V(D)J recombination
signal sequences-binding protein; ZAS family, member 3"
/codon_start=1
/product="transcription factor HIVEP3 isoform a"
/protein_id="NP_078779.2"
/db_xref="GI:116089331"
/db_xref="CCDS:CCDS463.1"
/db_xref="GeneID:59269"
/db_xref="HGNC:13561"
/db_xref="MIM:606649"
/translation="
MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSNEEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPPNA
"
misc_feature 1669..1821
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q5T1R4.1);
Region: ZAS1"
misc_feature 1714..1788
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/note="Zinc-finger double domain; Region: zf-H2C2_2;
pfam13465"
/db_xref="CDD:205643"
misc_feature 1726..4317
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q5T1R4.1);
Region: No DNA binding activity or transactivation
activity, but complete prevention of TRAF-dependent
NF-Kappa-B activation, associates with TRAF2 and JUN (By
similarity)"
misc_feature 1885..1956
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q5T1R4.1);
Region: Acidic 1"
misc_feature 3019..3099
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/note="C2H2-type zinc finger; Region: zf-C2H2_6;
pfam13912"
/db_xref="CDD:206083"
misc_feature 3679..3744
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q5T1R4.1);
Region: Acidic 2"
misc_feature 3802..3822
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q5T1R4.1);
Region: Nuclear localization signal (Potential)"
misc_feature 6355..6513
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q5T1R4.1);
Region: ZAS2"
misc_feature 6397..6474
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/note="Zinc-finger double domain; Region: zf-H2C2_2;
pfam13465"
/db_xref="CDD:205643"
misc_feature 6544..6711
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q5T1R4.1);
Region: Acidic 3"
misc_feature 6985..6996
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/experiment="experimental evidence, no additional details
recorded"
/note="1; propagated from UniProtKB/Swiss-Prot (Q5T1R4.1);
Region: Repetitive region"
misc_feature 7003..7014
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/experiment="experimental evidence, no additional details
recorded"
/note="2; propagated from UniProtKB/Swiss-Prot (Q5T1R4.1);
Region: Repetitive region"
misc_feature 7072..7083
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/experiment="experimental evidence, no additional details
recorded"
/note="3; propagated from UniProtKB/Swiss-Prot (Q5T1R4.1);
Region: Repetitive region"
misc_feature 7087..7098
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/experiment="experimental evidence, no additional details
recorded"
/note="4; propagated from UniProtKB/Swiss-Prot (Q5T1R4.1);
Region: Repetitive region"
misc_feature 7252..7539
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q5T1R4.1);
Region: 6 X 4 AA tandem repeats of S-P-X-[RK]"
variation 1198
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="a"
/replace="g"
/db_xref="dbSNP:2146315"
variation 1529
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="a"
/replace="t"
/db_xref="dbSNP:2181280"
variation 2022
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="c"
/replace="t"
/db_xref="dbSNP:35798350"
variation 2424
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="c"
/replace="g"
/db_xref="dbSNP:2475842"
variation 2532
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="c"
/replace="t"
/db_xref="dbSNP:2984694"
variation 2874
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="c"
/replace="t"
/db_xref="dbSNP:35586296"
variation 3177
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="a"
/replace="g"
/db_xref="dbSNP:36086247"
variation 5073
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="c"
/replace="t"
/db_xref="dbSNP:35624100"
variation 5079
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="a"
/replace="g"
/db_xref="dbSNP:35784470"
variation 5794
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="c"
/replace="t"
/db_xref="dbSNP:34970884"
variation 5817
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="a"
/replace="g"
/db_xref="dbSNP:35730380"
exon 6157..6302
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/inference="alignment:Splign:1.39.8"
exon 6303..6478
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/inference="alignment:Splign:1.39.8"
variation 6423
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="c"
/replace="t"
/db_xref="dbSNP:35122733"
exon 6479..6565
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/inference="alignment:Splign:1.39.8"
exon 6566..7500
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/inference="alignment:Splign:1.39.8"
variation 7162
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="c"
/replace="g"
/db_xref="dbSNP:2483689"
variation 7421
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="a"
/replace="c"
/db_xref="dbSNP:2991344"
exon 7501..12402
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/inference="alignment:Splign:1.39.8"
variation 10180
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="c"
/replace="t"
/db_xref="dbSNP:2151674"
STS 10726..10948
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/standard_name="RH64713"
/db_xref="UniSTS:75322"
variation 11089
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="c"
/replace="t"
/db_xref="dbSNP:3738577"
STS 11560..11690
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/standard_name="RH79040"
/db_xref="UniSTS:64983"
STS 11611..11805
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/standard_name="SHGC-74654"
/db_xref="UniSTS:59887"
variation 11662
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="a"
/replace="g"
/db_xref="dbSNP:11550923"
variation 11879
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace=""
/replace="aaaag"
/db_xref="dbSNP:71062591"
variation 11880..11884
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace=""
/replace="aaacg"
/db_xref="dbSNP:3841837"
STS 12027..12124
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/standard_name="SHGC-74661"
/db_xref="UniSTS:8905"
variation 12155
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
/replace="a"
/replace="g"
/db_xref="dbSNP:1127985"
polyA_signal 12379..12384
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
polyA_site 12402
/gene="HIVEP3"
/gene_synonym="KBP-1; KBP1; KRC; Schnurri-3; SHN3; ZAS3;
ZNF40C"
ORIGIN
ctcacaaccagccgactctcccattatccagctgcctagtttggtgcttcaatgtacatggctattccgtgtgcatatgtgtgtatacaaacacgcatgcatgcctggatggacatacgtatgcacaggttattttttaaggacaattctttcaataaggtctttaccccttacttgaaacaggtgttcatgaaaaaaatgcacaaaatcctgcctggccggaataattcatgaagaaggggctggatccgtgggtcagagaacacaggaccagtttgccatcccaaggccgaaggcctccctccaacacagttctccaagctctagaaatctctgacacatcttgaccatgagaccacggctggtttttggcaggattcgaggcacaaacccagcagcctcaacctagttcatggaggagcctcgcggggtcctggccaagcaagcccgcccctctggtgggaagagcggcgcctaggtggagggtggctgccgtaggagtggacatgaatgctggctttcagagagaacagcgtttcagttttggtcatcggaagtggtgccttcagcacagaagaagagcgtgatttctcctccaaggccgttgatctccaacccagaactaaaggggagaagagccacccccagcatccagcgtggcatctcttgtgccaggaccagggatgactgggccatggacacagatgtctccaaccttcaaccgtttgcatagcacacgggggactcgtgggggccacctgccactgccagctgaaacaatacaatggcaatactgacatccttcatgacgttttcccgacagacattcaggcagaaagtgctggtgcgttttctgtctgcaaagtagagggccatgcctcaccaatagaatagcgtgggccctgatgacctgctccgagtccactcacagccagtgacacttgcaaaaaactcccaaagccgtcttgggtttggctcccacagctcttgaccaatgtggccaaagctggacacctccttgggacactgggattattcataaatgcagcccgccctgactctccctgaatagcatctgaagtctttgtgaaggtcatggatcctgaacaaagtgtcaagggcaccaagaaggctgagggaagtccccggaagcggctgaccaaaggagaggccattcagaccagtgtttcttccagcgtcccatacccaggcagcggcacagctgccacccaagagagccccgcccaagagctcttagccccgcagcccttcccgggcccctcatcagttcttagggaaggctctcaggagaaaacgggccagcagcagaagccccccaaaaggccccccatcgaagcatccgtccacatctcacagcttccgcagcaccctctgacaccagcattcatgtcgcctggcaaacctgagcatctcctggaggggtccacatggcaactggttgaccccatgagacctggaccctctggctccttcgtggcccctgggctccatcctcagagccagctccttccttcccacgcttccatcattccccccgaggaccttcctggagtccccaaagtcttcgtgcctcgtccttcccaggtctccttgaagcccacagaagaggcacacaagaaggagaggaagccccagaagccaggcaagtacatctgccagtactgcagccggccctgtgccaagcccagcgtgctccagaagcacattcgctcacacacaggtgagaggccctacccctgcggcccctgtggcttctccttcaagaccaagagtaatctctacaagcacaggaagtcccatgcccaccgcatcaaagcaggcctggcctcaggcatgggtggcgagatgtacccacatgggctggagatggagcggatccctggggaagagtttgaggagcccactgagggagaaagcacagattctgaagaggagactagtgccacctctggtcaccctgcagagctctccccaagacccaagcagccccttctctccagcgggctatacagctctgggagccacagttccagccacgaacgctgttccctgtcccagtccagcacagcccagtcactcgaagacccccctccatttgtggaaccctcatctgagcaccccctgagccataaacctgaagacacccacacgattaagcagaagctggccctccgcttaagcgagaggaagaaggtgatcgatgagcaggcgtttctgagcccaggcagcaaagggagtactgagtctgggtatttctctcgctccgagagtgcagagcagcaggtcagccccccaaacaccaacgccaagtcctacgctgagatcatctttggcaagtgtgggcgaataggacagcggaccgccatgctgacagccacctccacccagcccctcctgcccctgtccaccgaagacaagcccagcctggtgcctttgtctgtaccccggacgcaggtgatcgagcacatcacgaagctcatcaccatcaacgaggccgtggtggacaccagcgagatcgacagcgtgaagccaaggcggagctcactgtccaggcgcagcagcatggagtccccaaaatccagcctctaccgggagcccctgtcatcccacagtgagaaaaccaagcctgaacaatcactgctgagcctccagcacccgcccagtaccgccccccctgtgcctctcctgagaagccactcaatgccttctgccgcctgcactatcagcaccccccaccaccccttccgaggtagctactccttcgatgaccatatcaccgactccgaagccctgagccacagcagtcacgtgtttacctcccacccccggatgctgaagcgccagccggcaatcgaattacctttgggaggggaatacagttctgaggagcctggcccaagcagcaaagacacagcctccaagccctcggacgaagtggaacccaaggaaagcgagcttaccaaaaagaccaagaagggtttgaaaacaaaaggggtgatctacgaatgtaacatatgtggtgctcggtacaagaaaagggataactacgaagcccacaaaaaatactactgctcagagcttcagatcgcaaagcccatctctgcaggcacccacacatctccagaagctgaaaagagtcagattgagcatgagccgtggtcccaaatgatgcattacaaactgggaaccaccctggaactcactccactgaggaagaggaggaaagagaagagccttggggacgaggaagagccacctgcctttgagtccacaaaaagtcagtttggcagccccgggccatctgatgctgctcggaaccttcccctggagtccaccaagtcaccagcagaaccaagtaaatcagtgccctccttggagggacccacgggcttccagccaaggactcccaagccagggtccggttcagaatcagggaaggagaggagaacaacgtccaaagaaatttctgtcatccagcacaccagctcctttgagaaatctgattctctcgagcagccgagtggcttggaaggggaagacaaacctctggcccagttcccatcacccccacctgccccacacggacgctctgctcactccctgcagcctaagttggtccgccagcccaacattcaggttcctgagatcctagtaactgaggagcctgaccggccggacacagagccagagccgccccctaaggaacctgagaagactgaggagttccaatggccccagcgcagccagacacttgcccagctcccagctgagaagctgccacccaaaaagaagaggttgcgcctggcagagatggcccaatcatcaggggagtccagcttcgagtcctctgtgcctctgtctcgcagcccgagccaggaaagcaatgtctctttgagtgggtccagccgctcagcctcgtttgagagggatgaccatgggaaagccgaggcccccagtccctcatctgacatgcgccccaaacccctgggcacccacatgttgactgtccccagccaccacccacatgcccgagagatgcggaggtcagcctcagagcagagccccaacgtttcccattctgcccacatgaccgagacacgcagcaaatcctttgactatggcagcttgtccttgacaggcccttctgctccagccccagtggctccaccagcgcgggtggccccgccagagagaagaaaatgcttcttggtgagacaggcctctctgagcaggcctccagaatctgagttggaggttgcccccaagggaagacaggagagcgaagaaccacagccctcatccagtaaaccctctgccaaaagctcattgtcccagatttcctctgcggccacctcacatggtggacccccgggaggcaagggcccagggcaggacaggcccccattggggcccactgtgccctacacagaagcactgcaagtgttccaccaccccgttgcccagacacccctgcatgagaagccatacctgcccccaccagtctcccttttctccttccagcatctcgtgcagcatgagccaggacagtctccagaattcttctccacccaggccatgtccagcctcctgtcctcaccatactccatgcccccacttcctccctccttatttcaagccccaccgcttcctctccagcctactgttctgcacccaggccaactccatctcccccagctcatgcctcacccagccaacatccccttcaggcagcccccttccttcctccccatgccatacccgacctcctcagcactgtcttctgggtttttcctgcctctgcaatcccagtttgcacttcagctccctggtgatgtggaaagccatctgccccagatcaaaaccagcctggccccactggcaacaggaagtgctggcctctcccccagcacagagtacagcagtgacatccggctaccccctgtggctcccccagccagctcctcagcacctacatcagctcctccactggccctgcctgcctgtccagacaccatggtgtccctggttgtgcctgtccgtgttcagaccaatatgccgtcctatgggagcgcaatgtacaccaccctttcccagatcttggtcacccagtcccaaggcagctcagcaactgtggcacttcccaagtttgaggaacccccatcaaaggggacgactgtatgtggtgcagatgtgcatgaggttgggcccggcccttctgggttaagtgaagagcaaagcagagctttcccaactccatacctgagagtgcctgtgacattacctgaaagaaaaggcacttccctgtcatcagagagtatcttgagcctggaggggagttcatcaacagcagggggaagcaaacgtgtcctttcaccagctggcagccttgaacttaccatggaaacccagcagcaaaaaagagtgaaggaggaggaggcttccaaggcagatgaaaaacttgagctggtaaaaccatgcagtgtggtccttaccagcaccgaggatgggaagaggccagagaaatcccacttaggcaaccagggccaaggcaggagggagctagaaatgctgtccagcctgtcctcagatccatctgacacaaaggaaattcctcccctccctcaccctgcattgtcccatgggacagccccaggctcagaagctttgaaggaatatccccagccatctggcaaacctcaccgaagagggttgaccccactgagcgtgaagaaagaagattccaaggaacaacctgatctcccctccttggcacctccgagctctctgcctctgtcagaaacgtcctccagaccagccaagtcacaagaaggtacggactcaaagaaggtactgcagttccccagcctccacacaaccactaatgtcagttggtgctatttaaactacattaagccaaatcacatccagcatgcagataggaggtcctctgtttacgctggttggtgcataagtttgtacaaccccaaccttccgggggtttccactaaagctgctttgtccctcctgaggtctaagcagaaagtgagcaaagagacatacaccatggccacagctccgcatcctgaggcaggaaggcttgtgccatccagctcccgcaagccccgcatgacagaggttcacctcccttcactggtttccccggaaggccagaaagatctagctagagtggagaaggaagaagagaggagaggggagccggaggaggatgctcctgcctcccagagaggggagccggcgaggatcaaaatcttcgaaggagggtacaaatcaaacgaagagtatgtatatgtgcgaggccgcggccgagggaaatatgtttgtgaggagtgtggaattcgctgcaagaagcccagcatgctgaagaaacacatccgcacccacactgacgtccggccctatgtgtgcaagcactgtcactttgcttttaaaaccaaagggaatctgactaagcacatgaagtcgaaggcccacagcaaaaagtgccaagagacaggggtgctggaggagctggaagccgaagaaggaaccagtgacgacctgttccaggactcggaaggacgagagggttcagaggctgtggaggagcaccagttttcggacctggaggactcggactcagactcagacctggacgaagacgaggatgaggatgaggaggagagccaggatgagctgtccagaccatcctcagaggcgcccccgcctggcccaccacatgcactgcgggcagactcctcacccatcctgggccctcagcccccagatgcccccgcctctggcacggaggctacacgaggcagctcggtctcggaagctgagcgcctgacagccagcagctgctccatgtccagccagagcatgccgggcctcccctggctgggaccggcccctctgggctctgtggagaaagacacaggctcagccttgagctacaagcctgtgtccccaagaagaccgtggtccccaagcaaagaagcaggcagccgtccaccactagcccgcaaacactcgctaaccaaaaacgactcatctccccagcgatgctccccggcccgagaaccacaggcctcagccccaagcccacctggcctgcacgtggacccaggaaggggcatgggcgctctcccttgtgggtctccaagacttcagctgtctcctctcaccctctgccccctgggaagagaactggcccctcgagcacatgtgctctccaaactcgagggtaccaccgacccaggcctccccagatactcgcccaccaggagatggtctccaggtcaggccgagtcaccaccacggtcagcgccgccagggaagtgggccttggctgggccgggcagcccctcagcgggggagcatggcccaggcttggggctggacccacgggttctcttcccgcccgcgcctctacctcacaagctcctcagcagaagcccagagacctgcgcctccccgtggcagaaggccgagtcccgaagtccctcctgctcacccggccctgctcatcctctctcctcccgacccttctccgccctccatgacttccacggccacatcctggcccggacagaggagaacatcttcagccacctgcctctgcactcccagcacttgacccgtgccccatgtcccttgattcccatcggtgggatccagatggtgcaggcccggccaggagcccaccccaccctgctgccagggcccaccgcagcctgggtcagtggcttctccgggggtggcagcgacctgacaggggcccgggaggcccaggagcgaggccgctggagtcccactgagagctcgtcagcctccgtgtcgcctgtggctaaggtctccaaattcacactctcctcagagctggagggcggggactaccccaaggagagggagaggaccggcggaggcccgggcaggcctcctgactggacaccccatgggaccggggcacctgcagagcccacacccacgcacagcccctgcaccccacccgacaccttgccccggccgccccagggacgccgggcagcgcagtcctggagcccccgcttggagtccccgcgtgcaccgaccaaccccgagccttctgccaccccgccgctggaccgcagcagctctgtgggctgcctggcagaggcctctgcccgcttcccagcccggacgaggaacctctccggggaacccaggaccaggcaggactcccccaagccctcaggaagtggggagcccagggcacatccacatcagcctgaggacagggttccccccaacgcttagcctctctccaactgcttcagcatctggcttccagtgtccagcaacagacgtttccagccactttcctcgaatcatcccacttcctcagccccatctgtccctccgtccaggagctctcacggccccatctgttgtaccttcccatgtatgcagttacctgtgcctttttctacaccttttgttgcttaaaaagaaacaaaacaaatcacatacatacatttaaaaaaaaaacaacaacccacgaggagtctgaggctgtgaatagtttatggttttggggaaaggctgatggtgaagcctcctgaccctccccgctgtggttggcagccacccaccccagaggctggcagagggaaaggggtacactgagggagaaaggaaaaggaaacttcaaacaatatagaattaaatgtaaaaggaagcactcctgtgtacagatgcgatcaaggttcctgtttattgccacttcacccccctgcccagctcgtagccacccctctctgccagcagaaaggccagtgtccccaggcagaggggcacaaacacaggcaggtgacccccacccaggccccagcaggcaggcccagaaaaactaatcttttccttttttttttttttttttttttttgcaagaaaataaaatgatacttttcctaggatttcaacacaaaataataggtgcaggtagaaggaggagggctggctccccaagggctcctggatactctggtagtctgagtcatgggcccatcctggcactccacaggtgggcaggccaccccacccacgcacccccactccagacacctcccttctgcaccccaccctggccccctgggctggggaaggagccctgactgtccgtccctggctcccaagcccctgaccgaggcctcactctcctgttgcctcctctgttctaaaaccaccaaaccacccacaaaggcagaagtggcagggcccgagccctagcggccgttcctgagactgggttttgggttttgtttcatcttggtccctggggtacaagggagcctgttcccctcatggctgggtttttccagttctccacagcagaggtttgcggggaactgtttcaggaccactttgccacaggaccgtttccccccgtccctgcccctgtctccactaccccaaggaaatacccacaactgtggctggtggatacggcctggacctgtttgctgtcttacacctcttttttaaaaagagagaggatggtgtttgatacttcacccagccaccacagattcttttgacctagaggatttttgaattgtcctaactcgttggaattctccaaagcaatcagtgtgagccagtgcctcttccttacccacatctctactttcaagaagctgccctgcatttcctggggcaaaactctactttgtaagaaaaataataggaccagaaatttaaatcccaaattgaactatggaacttgaactctagcgtgttcgccccaactgggagaggtgagctttttcccagtgtttcagaactgattttctttactttctacaagggagggcagcacagggactacggttgaggcccgtgaaggctgggtttgatgccaccctatacagagcagggacctctctggctaatccccagtcctcagccaggctgtgtgaatcaagtgcctgccccagggctcttgagctattgaagctgcttgggtacaggacacagtaggtggggagggttaagacccttctgtgagttccctgtgcggggctgtacttgcctcttccaattcgtggcctttccctgcttggtccctactagacagacaaaccagccacagtccagcctgcagccagaccaccttgttcactcattctcctttgcctcagagctaagacaaaaatgagacagaaggcagggctccctgggagtccactgtgctccagggttctggggaatcagggttagccagcagctcctggctgcttccctcagagactagggctctcatcctccccaagagaagcagcaagcccagcctggaccacactgtccatattgctggacagtggcctgacagaaagtgactcctccaagtcccaggaggccagggcttttctcatccttgcctttcagccctaacccatgggactgcccacggattggagacttcaagggctgaggtctgggagctgcataaagggcattgcttcagcccaggttagaaatctgcctgggcaagctcttcctgccccagacctacaaagcagcagaccgggggctctggtggactagcccctgacattggtggggggccccacaccactccaccccaccctgccttccagctctcctgggcatttttctccctgtactcaaacagcctacccacccaaggtttcctccctgggcagcctagcaatgaacagtgcagccggcagggcagaggcccggcagtcaccgggcccgtcaggctcaggcagagaagccacaggggccaggagtcactggagactatttctaaatgatgggggtaaatgcacaaatagaatctcaccaaagggctgcctccacattgatgccgtgcccagagggacagaaccaatgccaccagcctgggtatatgtcactgggcacagctctaaccccctcctccggactctagtcccgctcctctgcgcacagagcccccagcccacaggtacaccttcatgatttggagaaagacgctcgccccatgcacgccctcctctgggccttctgccctgctcccagtcacttccaagcttcctgtttgcctgtgatgttattgtgcctgttgagggaagcagcagaggaggcagtggctgacttggcacagatgcctgctacgtgctctgttgaaatgcgcggggtggccattcctcggtacagactagtcctggtccttgggtgtgggcagtgggggaggaaccaactggtcgaggtttcagagccaaaccttgcctttggttggtgagtccttgccccccaggcctgcgctccacgatgcctttcacccttggcaatctcagggccatcctgggtagtaaccccactcctctctgctcccgcccgcacctgtggctctcactctgggctcaacccctgcaaccctccaggagcccgacagcagccagctgcctgcactgtcgcctccgtaagctccaacttccagacccagaagtccctctgcttccctctgttggaaaaagcctaaaagaattagcttccagattcctctagcccctgctccattcccacccagtccttctgaagaggaatgagcaatacatctgagctggatttctctctagtcctttctccagacaaatccttcttaaagcaaaagtcctggctgagcacctgtccttggggaccgatctgccgtgtgaccaggggaagaaagttcccgaaagcctgttccaccaattctgcttctgtgttgtgaatccagtctgctttccattagaaaaccgcttcggcacttatggtcactttaataaatctagtatgtaaaaaaagaaagaaagaaaagaaacagaaaaaagaaacgtgcaggcaaatgtaaaatacaatgctctctgtaagataaatatttgcctttttttctaaaaggtgtacgtattctgtatgtgaaattgtctgtagaaagtttctatgttcttaaatggcaatacattccaaaaattgtactgtagatatgtacagcaaccgcactgggatggggtagttttgcctgtaattttatttaaactccagtttccacacttgcatcttgcaatgttggtatggtatatatcagtgcaaaagaaaaaacaaaacagaaacaaacaaaaaaaaaaaacaaaaatccacgcaggtctaaagcacagagtctgacgtacaaaaggaaaaatgctcagtattgatgtgtgtgacctttgttgtaaattacatctgtactgtgaatgagaagtttttacaagtataataattgcctttattacagctctggctgagtgttcagcctgaggatattttttaaaaaaaaaagaattagcatgttggaataaatttgaaaatcccaacataaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:59269 -> Molecular function: GO:0003677 [DNA binding] evidence: IEA
GeneID:59269 -> Molecular function: GO:0046872 [metal ion binding] evidence: IEA
GeneID:59269 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
GeneID:59269 -> Biological process: GO:0035914 [skeletal muscle cell differentiation] evidence: IEA
GeneID:59269 -> Biological process: GO:0045893 [positive regulation of transcription, DNA-dependent] evidence: IDA
GeneID:59269 -> Cellular component: GO:0005634 [nucleus] evidence: IEA
GeneID:59269 -> Cellular component: GO:0005737 [cytoplasm] evidence: IEA
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