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2024-04-25 22:18:04, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_023079               3137 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens ubiquitin-conjugating enzyme E2Z (UBE2Z), mRNA.
ACCESSION   NM_023079 XM_941930 XM_945544 XM_945547 XM_945549
VERSION     NM_023079.4  GI:302191680
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3137)
  AUTHORS   Schunkert,H., Konig,I.R., Kathiresan,S., Reilly,M.P., Assimes,T.L.,
            Holm,H., Preuss,M., Stewart,A.F., Barbalic,M., Gieger,C.,
            Absher,D., Aherrahrou,Z., Allayee,H., Altshuler,D., Anand,S.S.,
            Andersen,K., Anderson,J.L., Ardissino,D., Ball,S.G.,
            Balmforth,A.J., Barnes,T.A., Becker,D.M., Becker,L.C., Berger,K.,
            Bis,J.C., Boekholdt,S.M., Boerwinkle,E., Braund,P.S., Brown,M.J.,
            Burnett,M.S., Buysschaert,I., Carlquist,J.F., Chen,L., Cichon,S.,
            Codd,V., Davies,R.W., Dedoussis,G., Dehghan,A., Demissie,S.,
            Devaney,J.M., Diemert,P., Do,R., Doering,A., Eifert,S.,
            Mokhtari,N.E., Ellis,S.G., Elosua,R., Engert,J.C., Epstein,S.E., de
            Faire,U., Fischer,M., Folsom,A.R., Freyer,J., Gigante,B.,
            Girelli,D., Gretarsdottir,S., Gudnason,V., Gulcher,J.R.,
            Halperin,E., Hammond,N., Hazen,S.L., Hofman,A., Horne,B.D.,
            Illig,T., Iribarren,C., Jones,G.T., Jukema,J.W., Kaiser,M.A.,
            Kaplan,L.M., Kastelein,J.J., Khaw,K.T., Knowles,J.W., Kolovou,G.,
            Kong,A., Laaksonen,R., Lambrechts,D., Leander,K., Lettre,G., Li,M.,
            Lieb,W., Loley,C., Lotery,A.J., Mannucci,P.M., Maouche,S.,
            Martinelli,N., McKeown,P.P., Meisinger,C., Meitinger,T.,
            Melander,O., Merlini,P.A., Mooser,V., Morgan,T., Muhleisen,T.W.,
            Muhlestein,J.B., Munzel,T., Musunuru,K., Nahrstaedt,J.,
            Nelson,C.P., Nothen,M.M., Olivieri,O., Patel,R.S., Patterson,C.C.,
            Peters,A., Peyvandi,F., Qu,L., Quyyumi,A.A., Rader,D.J.,
            Rallidis,L.S., Rice,C., Rosendaal,F.R., Rubin,D., Salomaa,V.,
            Sampietro,M.L., Sandhu,M.S., Schadt,E., Schafer,A., Schillert,A.,
            Schreiber,S., Schrezenmeir,J., Schwartz,S.M., Siscovick,D.S.,
            Sivananthan,M., Sivapalaratnam,S., Smith,A., Smith,T.B.,
            Snoep,J.D., Soranzo,N., Spertus,J.A., Stark,K., Stirrups,K.,
            Stoll,M., Tang,W.H., Tennstedt,S., Thorgeirsson,G.,
            Thorleifsson,G., Tomaszewski,M., Uitterlinden,A.G., van Rij,A.M.,
            Voight,B.F., Wareham,N.J., Wells,G.A., Wichmann,H.E., Wild,P.S.,
            Willenborg,C., Witteman,J.C., Wright,B.J., Ye,S., Zeller,T.,
            Ziegler,A., Cambien,F., Goodall,A.H., Cupples,L.A., Quertermous,T.,
            Marz,W., Hengstenberg,C., Blankenberg,S., Ouwehand,W.H., Hall,A.S.,
            Deloukas,P., Thompson,J.R., Stefansson,K., Roberts,R.,
            Thorsteinsdottir,U., O'Donnell,C.J., McPherson,R., Erdmann,J. and
            Samani,N.J.
  CONSRTM   Cardiogenics; CARDIoGRAM Consortium
  TITLE     Large-scale association analysis identifies 13 new susceptibility
            loci for coronary artery disease
  JOURNAL   Nat. Genet. 43 (4), 333-338 (2011)
   PUBMED   21378990
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3137)
  AUTHORS   Gu,X., Zhao,F., Zheng,M., Fei,X., Chen,X., Huang,S., Xie,Y. and
            Mao,Y.
  TITLE     Cloning and characterization of a gene encoding the human putative
            ubiquitin conjugating enzyme E2Z (UBE2Z)
  JOURNAL   Mol. Biol. Rep. 34 (3), 183-188 (2007)
   PUBMED   17160626
  REMARK    GeneRIF: UBE2Z was widely expressed in human tissues and is located
            on chromosome 17q21.
REFERENCE   3  (bases 1 to 3137)
  AUTHORS   Jin,J., Li,X., Gygi,S.P. and Harper,J.W.
  TITLE     Dual E1 activation systems for ubiquitin differentially regulate E2
            enzyme charging
  JOURNAL   Nature 447 (7148), 1135-1138 (2007)
   PUBMED   17597759
  REMARK    GeneRIF: In tissue culture cells, Uba6 is required for charging a
            previously uncharacterized Uba6-specific E2 (Use1), whereas Ube1 is
            required for charging the cell-cycle E2s Cdc34A and Cdc34B
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC091133.11, BC015890.1, AL713782.1, AK122770.1 and AA845421.1.
            On Aug 5, 2010 this sequence version replaced gi:150417998.
            
            Summary: This gene encodes an enzyme which ubiquitinates proteins
            which participate in signaling pathways and apoptosis. [provided by
            RefSeq, Feb 2012].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC015890.1, AK122770.1, BC015890.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025082 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-132               AC091133.11        132267-132398       c
            133-980             BC015890.1         1-848
            981-1328            AL713782.1         137-484
            1329-2405           AK122770.1         1227-2303
            2406-3122           BC015890.1         2274-2990
            3123-3137           AA845421.1         1-15                c
FEATURES             Location/Qualifiers
     source          1..3137
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q21.32"
     gene            1..3137
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /note="ubiquitin-conjugating enzyme E2Z"
                     /db_xref="GeneID:65264"
                     /db_xref="HGNC:25847"
                     /db_xref="MIM:611362"
     exon            1..452
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /inference="alignment:Splign:1.39.8"
     variation       27
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:71144541"
     variation       32
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200920680"
     CDS             136..1200
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /EC_number="6.3.2.19"
                     /note="UBA6-specific enzyme E2; ubiquitin-protein ligase
                     Z; ubiquitin carrier protein Z; uba6-specific E2
                     conjugating enzyme 1"
                     /codon_start=1
                     /product="ubiquitin-conjugating enzyme E2 Z"
                     /protein_id="NP_075567.2"
                     /db_xref="GI:150417999"
                     /db_xref="CCDS:CCDS11540.2"
                     /db_xref="GeneID:65264"
                     /db_xref="HGNC:25847"
                     /db_xref="MIM:611362"
                     /translation="
MAESPTEEAATAGAGAAGPGASSVAGVVGVSGSGGGFGPPFLPDVWAAAAAAGGAGGPGSGLAPLPGLPPSAAAHGAALLSHWDPTLSSDWDGERTAPQCLLRIKRDIMSIYKEPPPGMFVVPDTVDMTKIHALITGPFDTPYEGGFFLFVFRCPPDYPIHPPRVKLMTTGNNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSISSVLISIQSLMTENPYHNEPGFEQERHPGDSKNYNECIRHETIRVAVCDMMEGKCPCPEPLRGVMEKSFLEYYDFYEVACKDRLHLQGQTMQDPFGEKRGHFDYQSLLMRLGLIRQKVLERLHNENAEMDSDSSSSGTETDLHGSLRV
"
     misc_feature    442..>744
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /note="Ubiquitin-conjugating enzyme E2, catalytic (UBCc)
                     domain. This is part of the ubiquitin-mediated protein
                     degradation pathway in which a thiol-ester linkage forms
                     between a conserved cysteine and the C-terminus of
                     ubiquitin and complexes with ubiquitin...; Region: UBCc;
                     cd00195"
                     /db_xref="CDD:29157"
     misc_feature    order(610..615,739..744)
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /note="E3 interaction residues; other site"
                     /db_xref="CDD:29157"
     misc_feature    order(643..645,661..663,673..678,682..684,694..702,
                     706..711,733..738)
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /note="Ub thioester intermediate interaction residues;
                     other site"
                     /db_xref="CDD:29157"
     misc_feature    697..699
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /note="active site cysteine"
                     /db_xref="CDD:29157"
     variation       186
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:371282577"
     exon            453..525
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /inference="alignment:Splign:1.39.8"
     exon            526..713
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /inference="alignment:Splign:1.39.8"
     variation       603
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372197104"
     variation       626
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375589561"
     variation       683
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144649420"
     exon            714..825
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /inference="alignment:Splign:1.39.8"
     variation       731
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:14421"
     variation       798
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:138545057"
     variation       816
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:149295614"
     exon            826..938
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /inference="alignment:Splign:1.39.8"
     variation       876
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:57077857"
     variation       882
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:374805356"
     variation       920
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:148048743"
     variation       936
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199614205"
     exon            939..1029
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /inference="alignment:Splign:1.39.8"
     variation       957
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143741978"
     variation       972
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147448373"
     variation       981
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1058018"
     variation       982
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183767062"
     variation       1023
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369952699"
     exon            1030..3126
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /inference="alignment:Splign:1.39.8"
     variation       1038
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376224551"
     variation       1050
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200801877"
     variation       1109
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1058017"
     variation       1158
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:145854510"
     variation       1202
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370323738"
     variation       1223
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375182716"
     variation       1230
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:373393504"
     variation       1427
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2088138"
     variation       1465..1466
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:371315163"
     variation       1466
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148572493"
     variation       1722
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:78183148"
     variation       1897
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:15563"
     variation       2085
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3744611"
     variation       2119..2120
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:35412283"
     STS             2139..2380
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /standard_name="A009L01"
                     /db_xref="UniSTS:71484"
     STS             2139..2380
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /standard_name="G32634"
                     /db_xref="UniSTS:117217"
     variation       2156
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:114544818"
     variation       2213
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1057897"
     STS             2214..2334
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /standard_name="RH17824"
                     /db_xref="UniSTS:73832"
     variation       2246
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:55685312"
     variation       2262
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:28384242"
     variation       2292
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1057902"
     variation       2388
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:183523260"
     variation       2405..2406
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:201929916"
     variation       2483
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113236693"
     variation       2498
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:7221215"
     variation       2602
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:192998454"
     variation       2728
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:375342301"
     variation       2770..2771
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace=""
                     /replace="tga"
                     /db_xref="dbSNP:144120233"
     variation       2771..2772
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace=""
                     /replace="gag"
                     /replace="tga"
                     /db_xref="dbSNP:370886107"
     variation       2774..2775
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace=""
                     /replace="tga"
                     /db_xref="dbSNP:71661305"
     variation       2774
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:113522189"
     variation       2777
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113446783"
     variation       2790
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185251725"
     variation       2802
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145544916"
     variation       2862
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147694058"
     variation       2917
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:3205390"
     variation       3054
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:189626966"
     variation       3075..3076
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:71369239"
     variation       3084
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200294094"
     variation       3089
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11557620"
     variation       3120
                     /gene="UBE2Z"
                     /gene_synonym="HOYS7; USE1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3179960"
ORIGIN      
agcaccgtctgggctgtggaagcggagggggtggggacactctggcccggttctcggtggtgcgggagcgggcgggagcagcggccgctctggtcggcggacgtgctgccgagtagtcccggaagcgaagcagcgatggcggagagtccgactgaggaggcggcaacggcgggcgccggggcggcgggccccggggcgagcagcgttgctggtgttgttggcgttagcggcagcggcggcgggttcgggccgcctttcctgccggatgtgtgggcggcggcggcggcagcgggcggggccgggggcccggggagcggcctggctccgctgcccgggctcccgccctcagccgctgcccacggggccgcgctgcttagccactgggaccccacgctcagctccgactgggacggcgagcgcaccgcgccgcagtgtctactccggatcaagcgggatatcatgtccatttataaggagcctcctccaggaatgttcgttgtacctgatactgttgacatgactaagattcatgcattgatcacaggcccatttgacactccttatgaagggggtttcttcctgttcgtgtttcggtgtccgcccgactatcccatccacccacctcgggtcaaactgatgacaacgggcaataacacagtgaggtttaaccccaacttctaccgcaatgggaaagtctgcttgagtattctaggtacatggactggacctgcctggagcccagcccagagcatctcctcagtgctcatctctatccagtccctgatgactgagaacccctatcacaatgagcccggctttgaacaggagagacatccaggagacagcaaaaactataatgaatgtatccggcacgagaccatcagagttgcagtctgtgacatgatggaaggaaagtgtccctgtcctgaacccctacgaggggtgatggagaagtcctttctggagtattacgacttctacgaggtggcctgcaaagatcgcctgcaccttcaaggccaaactatgcaggacccttttggagagaagcggggccactttgactaccagtccctcttgatgcgcctgggactgatacgtcagaaagtgctggagaggctccataatgagaatgcagaaatggactctgatagcagttcatctgggacagagacagaccttcatgggagcctgagggtttagaccctgctcccatctccccttcccccactcaagagtcccagcagaatcccttccccccaccccagggatggagaggcactgtgtatctccctccagactcgaagtcatcctgcaagatggcaagaaccaagcaagctccgatcccagggtgtgggagtgggggcctgttcccggtctgacctccttggcactggagcatctggggcttcgttcatccattcatcccgtatcaggggccaaggtacctttacaggagcacctagagcgagggcctttggcaaaaacaaaacaaccaacacacctctccacagggccagctccttagggataagtggaagatggaaattgcaattccaagagggagtgtgcccaaatgatttatggggatacctggaagggagcttggggtgggggctgtctgtgacacttaagcagtctgggtggttgtctatttgtctgtcttcagtcttgaagcagggcttcccaatgcccttttcctccctgccttccttcccccattatttcccacaggccagcataattttgtttttcctaatttatagtcactgttctagacagaccaaagagaaggaacagtggtggagtctaggctgctgatcagtaagctttacctagcacctgagcacctttctcccctcccctctttcctcacccttttctagatgtaagacagaaagtaaatgtgactgggacttaaccaaggtcttggtaaagcctgcatggcaccgtaagaagctgaaaatactgtttgttcccgcaatcactgatttgaaaagttcccaacacaggcagctgctgtgtatatgggattagagccactacatagaatagtctcttacagattttcataaatactagtcacaataagggtatttttcttgggggtggagtaagggggagactgatgctagtccttgttgtattttgttgggctgtccttgtgtattttcaccccagcctgtagtcctcctcacttcaaccccagggatttttggggagcaagggtagccaatggcagagggggttggggctgggactctggaggctcctccccttctttctcttccttccgcctcccccgtgcccccagctgctcttgtcactgtctctgatgggtatttgcctggctttgttgcttctctatctgtatttagctgcagtgatcctttagctggttggctcagaaaaaaaaaaatgtgctttaggtgccctgtaatcctgggcatcaagggaatccatccttcccctttttgatatgttctccccgtacttccagatttattgttatggctcccagtgggtattggcgattcttgtgatgcagggcctcagtcagtgtccagccatgcataagggagaggatagtgtgtacctgccctgccctctgctatgaaggtctctgccttgtggatcatgggactccccttggaggatctgtgcaaaggggggctgggcacaaaggagaatgtcctatttgggagggcaggaagcaaaggaactggacagggattggtgggcttggggaacggaagtttatcttggatacccttgaagaggctgggtctcttcacatgaagatcgaaaagggaccctgcttccaatttccctcttccattcctcgagctactccagggcttagaagaatgctcttggtctgtgggtccagtgttgtctgtcatccatttaagtgttcccactttcaagtgacaatcctctccttggccctgccatagggcagagcatgtctggcatagcagcctgacttttatgccctaatcttgagttgaggaaatatatgcacaggagtcaaagagatgtctttatatctgactgtatataaatgaagtttttttgttttttttgttttcctttttggtgcaataaagtttgttttggcagaaggagaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:65264 -> Molecular function: GO:0004842 [ubiquitin-protein ligase activity] evidence: IEA
            GeneID:65264 -> Molecular function: GO:0005524 [ATP binding] evidence: IEA
            GeneID:65264 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
            GeneID:65264 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:65264 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
            GeneID:65264 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
ANNOTATIONS from NCBI Entrez Gene (20130726):
            NP_075567 -> EC 6.3.2.19

by @meso_cacase at DBCLS
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