Home |
Help |
Advanced search
2024-04-19 22:48:03, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_022362 3703 bp mRNA linear PRI 07-JUL-2013
DEFINITION Homo sapiens MMS19 nucleotide excision repair homolog (S.
cerevisiae) (MMS19), mRNA.
ACCESSION NM_022362
VERSION NM_022362.4 GI:170763478
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3703)
AUTHORS van Wietmarschen,N., Moradian,A., Morin,G.B., Lansdorp,P.M. and
Uringa,E.J.
TITLE The mammalian proteins MMS19, MIP18, and ANT2 are involved in
cytoplasmic iron-sulfur cluster protein assembly
JOURNAL J. Biol. Chem. 287 (52), 43351-43358 (2012)
PUBMED 23150669
REMARK GeneRIF: The mammalian proteins MMS19, MIP18, and ANT2 are involved
in cytoplasmic iron-sulfur cluster protein assembly.
REFERENCE 2 (bases 1 to 3703)
AUTHORS Stehling,O., Vashisht,A.A., Mascarenhas,J., Jonsson,Z.O.,
Sharma,T., Netz,D.J., Pierik,A.J., Wohlschlegel,J.A. and Lill,R.
TITLE MMS19 assembles iron-sulfur proteins required for DNA metabolism
and genomic integrity
JOURNAL Science 337 (6091), 195-199 (2012)
PUBMED 22678362
REMARK GeneRIF: identified MMS19 as a member of the cytosolic iron-sulfur
protein assembly (CIA) machinery; MMS19 functions as part of the
CIA targeting complex that interacts with and facilitates
iron-sulfur cluster insertion into apoproteins involved in
methionine biosynthesis, DNA replication, DNA repair, and telomere
maintenance
REFERENCE 3 (bases 1 to 3703)
AUTHORS Gari,K., Leon Ortiz,A.M., Borel,V., Flynn,H., Skehel,J.M. and
Boulton,S.J.
TITLE MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA
metabolism
JOURNAL Science 337 (6091), 243-245 (2012)
PUBMED 22678361
REMARK GeneRIF: study demonstrates MMS19 forms a complex with the
cytoplasmic Fe-S assembly (CIA) proteins CIAO1, IOP1 and MIP18;
cytoplasmic MMS19 also binds to multiple nuclear Fe-S proteins
involved in DNA metabolism; propose that MMS19 functions as a
platform to facilitate Fe-S cluster transfer to proteins critical
for DNA replication and repair
REFERENCE 4 (bases 1 to 3703)
AUTHORS Ito,S., Tan,L.J., Andoh,D., Narita,T., Seki,M., Hirano,Y.,
Narita,K., Kuraoka,I., Hiraoka,Y. and Tanaka,K.
TITLE MMXD, a TFIIH-independent XPD-MMS19 protein complex involved in
chromosome segregation
JOURNAL Mol. Cell 39 (4), 632-640 (2010)
PUBMED 20797633
REMARK GeneRIF: Results indicate that the MMS19-XPD protein complex is
required for proper chromosome segregation, an abnormality of which
could contribute to the pathogenesis in some cases of xeroderma
pigmentosum.
REFERENCE 5 (bases 1 to 3703)
AUTHORS Briggs FB, Goldstein BA, McCauley JL, Zuvich RL, De Jager PL, Rioux
JD, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Oksenberg JR,
Sawcer SJ, Pericak-Vance MA, Haines JL and Barcellos LF.
CONSRTM International Multiple Sclerosis Genetics Consortium
TITLE Variation within DNA repair pathway genes and risk of multiple
sclerosis
JOURNAL Am. J. Epidemiol. 172 (2), 217-224 (2010)
PUBMED 20522537
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 6 (bases 1 to 3703)
AUTHORS Hatfield,M.D., Reis,A.M., Obeso,D., Cook,J.R., Thompson,D.M.,
Rao,M., Friedberg,E.C. and Queimado,L.
TITLE Identification of MMS19 domains with distinct functions in NER and
transcription
JOURNAL DNA Repair (Amst.) 5 (8), 914-924 (2006)
PUBMED 16797255
REMARK GeneRIF: MMS19 HEAT repeat domain is essential for MMS19 function
in NER and transcription, while domains A and B, within MMS19
N-terminus, modulate the balance between DNA repair and
transcription.
REFERENCE 7 (bases 1 to 3703)
AUTHORS Grupe,A., Li,Y., Rowland,C., Nowotny,P., Hinrichs,A.L., Smemo,S.,
Kauwe,J.S., Maxwell,T.J., Cherny,S., Doil,L., Tacey,K., van
Luchene,R., Myers,A., Wavrant-De Vrieze,F., Kaleem,M.,
Hollingworth,P., Jehu,L., Foy,C., Archer,N., Hamilton,G.,
Holmans,P., Morris,C.M., Catanese,J., Sninsky,J., White,T.J.,
Powell,J., Hardy,J., O'Donovan,M., Lovestone,S., Jones,L.,
Morris,J.C., Thal,L., Owen,M., Williams,J. and Goate,A.
TITLE A scan of chromosome 10 identifies a novel locus showing strong
association with late-onset Alzheimer disease
JOURNAL Am. J. Hum. Genet. 78 (1), 78-88 (2006)
PUBMED 16385451
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 8 (bases 1 to 3703)
AUTHORS Wu,X., Li,H. and Chen,J.D.
TITLE The human homologue of the yeast DNA repair and TFIIH regulator
MMS19 is an AF-1-specific coactivator of estrogen receptor
JOURNAL J. Biol. Chem. 276 (26), 23962-23968 (2001)
PUBMED 11279242
REFERENCE 9 (bases 1 to 3703)
AUTHORS Queimado,L., Rao,M., Schultz,R.A., Koonin,E.V., Aravind,L.,
Nardo,T., Stefanini,M. and Friedberg,E.C.
TITLE Cloning the human and mouse MMS19 genes and functional
complementation of a yeast mms19 deletion mutant
JOURNAL Nucleic Acids Res. 29 (9), 1884-1891 (2001)
PUBMED 11328871
REMARK GeneRIF: Cloning of the human MMS19 genes and functional
complementation in Saccharomyces cerevisiae
REFERENCE 10 (bases 1 to 3703)
AUTHORS Seroz,T., Winkler,G.S., Auriol,J., Verhage,R.A., Vermeulen,W.,
Smit,B., Brouwer,J., Eker,A.P., Weeda,G., Egly,J.M. and
Hoeijmakers,J.H.
TITLE Cloning of a human homolog of the yeast nucleotide excision repair
gene MMS19 and interaction with transcription repair factor TFIIH
via the XPB and XPD helicases
JOURNAL Nucleic Acids Res. 28 (22), 4506-4513 (2000)
PUBMED 11071939
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
DC403135.1, DC410036.1, DC382327.1, AK314374.1 and BC009396.2.
On Mar 25, 2008 this sequence version replaced gi:157738691.
Sequence Note: A downstream start codon is selected for this RefSeq
based on better conservation with homologous proteins. The use of
an alternative upstream start codon, which is present in some
species, including human, chimp and macaque (with a subsequent CDS
frameshift in the latter species), would increase the protein
length from 1030 aa to 1051 aa. The shorter protein is referred to
in the literature, including PMIDs 11071939, 11279242 and 11328871.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AF357881.1, AJ306408.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
ERS025081, ERS025082 [ECO:0000350]
##Evidence-Data-END##
##RefSeq-Attributes-START##
CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
is not conserved
##RefSeq-Attributes-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-130 DC403135.1 113-242
131-162 DC410036.1 131-162
163-725 DC382327.1 1-563
726-2798 AK314374.1 524-2596
2799-3703 BC009396.2 865-1769
FEATURES Location/Qualifiers
source 1..3703
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/map="10q24-q25"
gene 1..3703
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/note="MMS19 nucleotide excision repair homolog (S.
cerevisiae)"
/db_xref="GeneID:64210"
/db_xref="HGNC:13824"
/db_xref="MIM:614777"
exon 1..337
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
misc_feature 109..111
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/note="upstream in-frame stop codon"
variation 144
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/replace="a"
/replace="c"
/db_xref="dbSNP:3750558"
misc_feature 163..165
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/note="alternative translation initiation codon"
CDS 226..3318
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/note="homolog of yeast MMS19; MET18 homolog; MMS19-like
(MET18 homolog, S. cerevisiae); MMS19-like protein"
/codon_start=1
/product="MMS19 nucleotide excision repair protein
homolog"
/protein_id="NP_071757.4"
/db_xref="GI:170763479"
/db_xref="CCDS:CCDS7464.1"
/db_xref="GeneID:64210"
/db_xref="HGNC:13824"
/db_xref="MIM:614777"
/translation="
MAAAAAVEAAAPMGALWGLVHDFVVGQQEGPADQVAADVKSGNYTVLQVVEALGSSLENPEPRTRARAIQLLSQVLLHCHTLLLEKEVVHLILFYENRLKDHHLVIPSVLQGLKALSLCVALPPGLAVSVLKAIFQEVHVQSLPQVDRHTVYNIITNFMRTREEELKSLGADFTFGFIQVMDGEKDPRNLLVAFRIVHDLISRDYSLGPFVEELFEVTSCYFPIDFTPPPNDPHGIQREDLILSLRAVLASTPRFAEFLLPLLIEKVDSEVLSAKLDSLQTLNACCAVYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSRSVLRADAEDLLDSFLSNILQDCRHHLCEPDMKLVWPSAKLLQAAAGASARACDSVTSNVLPLLLEQFHKHSQSSQRRTILEMLLGFLKLQQKWSYEDKDQRPLNGFKDQLCSLVFMALTDPSTQLQLVGIRTLTVLGAQPDLLSYEDLELAVGHLYRLSFLKEDSQSCRVAALEASGTLAALYPVAFSSHLVPKLAEELRVGESNLTNGDEPTQCSRHLCCLQALSAVSTHPSIVKETLPLLLQHLWQVNRGNMVAQSSDVIAVCQSLRQMAEKCQQDPESCWYFHQTAIPCLLALAVQASMPEKEPSVLRKVLLEDEVLAAMVSVIGTATTHLSPELAAQSVTHIVPLFLDGNVSFLPENSFPSRFQPFQDGSSGQRRLIALLMAFVCSLPRNVEIPQLNQLMRELLELSCCHSCPFSSTAAAKCFAGLLNKHPAGQQLDEFLQLAVDKVEAGLGSGPCRSQAFTLLLWVTKALVLRYHPLSSCLTARLMGLLSDPELGPAAADGFSLLMSDCTDVLTRAGHAEVRIMFRQRFFTDNVPALVQGFHAAPQDVKPNYLKGLSHVLNRLPKPVLLPELPTLLSLLLEALSCPDCVVQLSTLSCLQPLLLEAPQVMSLHVDTLVTKFLNLSSSPSMAVRIAALQCMHALTRLPTPVLLPYKPQVIRALAKPLDDKKRLVRKEAVSARGEWFLLGSPGS
"
misc_feature 283..462
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/note="NER and RNAPII transcription protein n terminal;
Region: MMS19_N; pfam12460"
/db_xref="CDD:204929"
misc_feature 352..468
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q96T76.2);
Region: HEAT 1"
misc_feature 982..1098
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q96T76.2);
Region: HEAT 2"
misc_feature 1384..1503
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q96T76.2);
Region: HEAT 3"
misc_feature 1711..1713
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-acetyllysine; propagated from
UniProtKB/Swiss-Prot (Q96T76.2); acetylation site"
misc_feature 2821..2937
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q96T76.2);
Region: HEAT 4"
misc_feature 2947..3063
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q96T76.2);
Region: HEAT 5"
misc_feature 3070..3186
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q96T76.2);
Region: HEAT 6"
misc_feature 3133..3279
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/note="HEAT-like repeat; Region: HEAT_EZ; pfam13513"
/db_xref="CDD:205691"
misc_feature 3193..3309
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q96T76.2);
Region: HEAT 7"
misc_feature 3304..3306
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q96T76.2); phosphorylation site"
exon 338..386
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
exon 387..487
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
exon 488..573
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
variation 517
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/replace="c"
/replace="t"
/db_xref="dbSNP:29001280"
exon 574..648
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
exon 649..718
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
exon 719..847
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
variation 814
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/replace="a"
/replace="g"
/db_xref="dbSNP:29001285"
exon 848..909
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
exon 910..996
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
exon 997..1071
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
exon 1072..1149
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
variation 1142
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/replace="a"
/replace="g"
/db_xref="dbSNP:29001306"
exon 1150..1288
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
exon 1289..1443
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
variation 1318
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/replace="a"
/replace="g"
/db_xref="dbSNP:29001309"
exon 1444..1522
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
variation 1451
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/replace="a"
/replace="c"
/db_xref="dbSNP:29001311"
exon 1523..1648
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
variation 1525
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/replace="c"
/replace="g"
/db_xref="dbSNP:29001314"
exon 1649..1730
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
exon 1731..1831
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
variation 1761
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/replace="a"
/replace="c"
/db_xref="dbSNP:29001317"
exon 1832..1981
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
exon 1982..2137
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
exon 2138..2237
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
exon 2238..2340
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
variation 2271
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/replace="c"
/replace="t"
/db_xref="dbSNP:29001324"
exon 2341..2409
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
exon 2410..2536
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
exon 2537..2637
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
variation 2594
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/replace="a"
/replace="g"
/db_xref="dbSNP:3740526"
exon 2638..2694
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
exon 2695..2881
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
variation 2799
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/replace="c"
/replace="t"
/db_xref="dbSNP:2152092"
STS 2830..3251
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/standard_name="MARC_27504-27505:1034367166:1"
/db_xref="UniSTS:269106"
exon 2882..2964
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
exon 2965..3129
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
exon 3130..3189
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
variation 3173
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/replace="a"
/replace="g"
/db_xref="dbSNP:29001332"
exon 3190..3290
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
exon 3291..3686
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/inference="alignment:Splign:1.39.8"
variation 3311
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/replace="a"
/replace="g"
/db_xref="dbSNP:36023427"
STS 3362..3494
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/standard_name="A002G19"
/db_xref="UniSTS:61952"
STS 3419..3602
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/standard_name="Cda19h12"
/db_xref="UniSTS:32942"
variation 3531
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
/replace="a"
/replace="g"
/db_xref="dbSNP:29001334"
polyA_signal 3666..3671
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
polyA_site 3686
/gene="MMS19"
/gene_synonym="hMMS19; MET18; MMS19L"
ORIGIN
aatcgcctccggctgcgtgcccagcagccgccttccctctcggtgccaccgccccatttcaggccccgcccctccctggaactgcctaggcagaagccggcaggcacgtgaccccggcgccccgcccccttgcgcttccccggagattggctcgggaggcgcatgcgcggagagcccgtctcgagccaccgcccatatcccctcccacggtctctagttcgcgttatggccgctgccgcggctgtggaggcggcggcgcctatgggtgccctatggggcctcgtgcacgacttcgtcgtgggtcagcaagagggccccgctgaccaggtggctgcagatgtgaaatctggcaactatacagtgttacaagttgtggaagcccttgggtcctctctagagaatccagaaccccgaactcgggcacgagcaatccagcttttgtcacaggtgctactccactgtcacaccttgctcctggagaaggaagtggtacacctgatactgttctatgagaaccggctgaaggaccatcatcttgtgatcccatctgtcctgcagggtttgaaggcacttagcctgtgtgtggccctgcccccagggctggctgtttctgtgcttaaagccatcttccaggaagtgcatgtacagtccctgccacaggtggaccgacacacagtctacaatatcatcaccaattttatgcgaacccgggaagaagagctaaagagcctaggagctgacttcacctttggcttcatccaggtgatggatggggaaaaggatccccgtaatcttctggtggccttccgcatcgtccatgacctcatctccagggactatagcctgggaccctttgtggaggagttgtttgaagtgacatcctgttatttccctatcgattttacccctccacctaatgatccccatggtatccagagagaagacctcatcctgagtcttcgcgctgtgctggcttctacaccacgatttgctgagtttctgctgcccctgttgattgagaaagtggattctgaggttctgagtgccaagttggattctctacagactctgaatgcttgctgtgctgtgtatggacagaaggaactgaaggacttcctccccagcctttgggcttctatccgcagagaggtgttccagacggcaagtgagcgggtggaggcagagggcctggcggccctccactccctgactgcgtgtttgtctcgctctgtgctgagggctgatgctgaggacctccttgactccttccttagcaacattctacaggactgcaggcaccacctgtgtgaaccggacatgaaactggtgtggcctagtgccaagctgttgcaggcagctgcaggtgcatctgcccgggcctgtgactctgtcaccagcaatgtactgcctttactgctggaacagttccacaagcacagtcagagcagccagcggcggacaatccttgaaatgctcctgggtttcttgaagctgcagcagaaatggagctatgaagacaaagatcaaaggcctctgaatggcttcaaggaccagctgtgctcactggtattcatggctctaacagaccccagcacccagcttcagcttgttggcatccgtacactgacagtcttgggtgcccagccagatctcctatcttatgaggacttggagctggcagtgggtcacctgtacagactgagcttcctgaaggaggattcccagagttgcagggtggcagcactggaagcatcaggaaccctggctgctctctaccctgtggccttcagcagccacctcgtacccaagctcgctgaggagctgcgtgtaggggagtcaaatttgactaacggagatgagcccacccaatgctcccggcatctgtgctgtctgcaagccttgtcagctgtatcaacacatcccagcatcgtcaaggagacactgcctctgctgctgcagcatctctggcaagtgaacagagggaatatggttgcacaatccagtgacgttattgctgtctgtcagagcctcagacagatggcagaaaaatgtcagcaggaccctgagagttgctggtatttccaccagacagctataccttgcctgcttgccttggctgtgcaggcctctatgccagagaaggagccctcagttctgagaaaagtactattggaggatgaggtgttggctgccatggtgtctgtcattggcactgctacaacccacctgagccctgagttagctgcccagagtgtgacacacattgtgcccctcttcttggatggcaacgtgtcctttctgcctgaaaacagcttcccgagcagattccagccattccaggatggctcctcagggcagaggcggctgattgcactgcttatggcctttgtctgctccctgcctcgaaatgtggaaatccctcagctgaaccaactcatgcgggagcttttggaactgagctgctgccacagctgccccttttcttccaccgctgctgccaagtgctttgcaggactcctcaacaagcaccctgcagggcagcagctggatgaattcctacagctagctgtggacaaagtggaggctggcctgggctctgggccctgtcgtagtcaggccttcactcttcttctctgggtaacaaaggccctagtgctcagataccatcctctcagctcctgccttacagcccggctcatgggcctcctgagtgacccagaattaggtccagcagcagctgatggcttctctctgctcatgtctgactgcactgatgtgctgactcgtgctggccatgccgaagtgcggatcatgttccgccagcggttcttcacagataatgtgcctgctttggtccagggcttccatgctgctccccaagatgtgaagccaaactacttgaagggtctttctcatgtacttaacaggctgcccaagcctgtactcttgccagagctgcccacgcttctttccttgctgctggaggccctgtcctgccctgactgtgtggtgcagctctccaccctcagctgccttcagcctcttctactggaagcaccccaagtcatgagtcttcacgtggacaccctcgtcaccaagtttctgaacctcagctctagcccttccatggctgtccggatcgccgcactgcagtgcatgcatgctctcactcgcctgcccacccctgtgctgctgccgtacaaaccacaggtgattcgggccttagccaaacccctggatgacaagaagagactggtgcgcaaggaagcagtgtcagccagaggggagtggtttctgttggggagccctggcagctgagccctcagtcctggcctagactgttctgacaatctaacctgggattactaactgttgagccatcttccccaaagcagggaaaccactggtctctgactgcctttcccacagacacagcacaaatgctaggcctctgttgcatggctgtacaaagaacataagagtccatatttctagtggatttgtaaaataagtgtgtgtgagacacttgcgtttgaagaaagatctagggtcctgggtctcttgcatttatatgtcagaaaaggggcgatatgctgctgaggggtgagtgcatatgagtgtggccctgaggaccagggctggcagatgttgtctacctgctgaagaataaagatttcttttggtaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:64210 -> Molecular function: GO:0003713 [transcription coactivator activity] evidence: IMP
GeneID:64210 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:64210 -> Molecular function: GO:0030159 [receptor signaling complex scaffold activity] evidence: NAS
GeneID:64210 -> Molecular function: GO:0030331 [estrogen receptor binding] evidence: IPI
GeneID:64210 -> Molecular function: GO:0030674 [protein binding, bridging] evidence: NAS
GeneID:64210 -> Biological process: GO:0000160 [phosphorelay signal transduction system] evidence: NAS
GeneID:64210 -> Biological process: GO:0006259 [DNA metabolic process] evidence: IMP
GeneID:64210 -> Biological process: GO:0006281 [DNA repair] evidence: IMP
GeneID:64210 -> Biological process: GO:0006289 [nucleotide-excision repair] evidence: NAS
GeneID:64210 -> Biological process: GO:0006289 [nucleotide-excision repair] evidence: TAS
GeneID:64210 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: NAS
GeneID:64210 -> Biological process: GO:0006974 [response to DNA damage stimulus] evidence: IMP
GeneID:64210 -> Biological process: GO:0007059 [chromosome segregation] evidence: IMP
GeneID:64210 -> Biological process: GO:0009725 [response to hormone stimulus] evidence: NAS
GeneID:64210 -> Biological process: GO:0016226 [iron-sulfur cluster assembly] evidence: IMP
GeneID:64210 -> Biological process: GO:0044281 [small molecule metabolic process] evidence: TAS
GeneID:64210 -> Biological process: GO:0045893 [positive regulation of transcription, DNA-dependent] evidence: IMP
GeneID:64210 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:64210 -> Cellular component: GO:0005634 [nucleus] evidence: TAS
GeneID:64210 -> Cellular component: GO:0005675 [holo TFIIH complex] evidence: NAS
GeneID:64210 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:64210 -> Cellular component: GO:0005819 [spindle] evidence: IDA
GeneID:64210 -> Cellular component: GO:0071817 [MMXD complex] evidence: IDA
GeneID:64210 -> Cellular component: GO:0097361 [CIA complex] evidence: IDA
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.