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2024-04-19 07:22:29, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_021079 4903 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens N-myristoyltransferase 1 (NMT1), mRNA.
ACCESSION NM_021079
VERSION NM_021079.3 GI:39725674
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4903)
AUTHORS Morgan,C.R., Miglionico,B.V. and Engen,J.R.
TITLE Effects of HIV-1 Nef on human N-myristoyltransferase 1
JOURNAL Biochemistry 50 (16), 3394-3403 (2011)
PUBMED 21449607
REMARK GeneRIF: we propose a model of the Nef:NMT complex in which only
the myristoyl moiety holds the two proteins together in complex and
speculate that perhaps NMT chaperones Nef to the membrane and
thereby protects the myristic acid group from the cytosol
REFERENCE 2 (bases 1 to 4903)
AUTHORS Takamune,N., Gota,K., Misumi,S., Tanaka,K., Okinaka,S. and Shoji,S.
TITLE HIV-1 production is specifically associated with human NMT1 long
form in human NMT isozymes
JOURNAL Microbes Infect. 10 (2), 143-150 (2008)
PUBMED 18248763
REMARK GeneRIF: These results strongly suggest that HIV-1 production is
specifically associated with hNMT1, particularly hNMT1(L), but not
with hNMT2 in vivo, contributing to the understanding of a step in
HIV-1 replication.
REFERENCE 3 (bases 1 to 4903)
AUTHORS Seaton,K.E. and Smith,C.D.
TITLE N-Myristoyltransferase isozymes exhibit differential specificity
for human immunodeficiency virus type 1 Gag and Nef
JOURNAL J. Gen. Virol. 89 (PT 1), 288-296 (2008)
PUBMED 18089753
REMARK GeneRIF: Nef is preferentially myristoylated by NMT2, suggesting
that selective inhibition of NMT2 may provide a novel means of
blocking HIV virulence.
REFERENCE 4 (bases 1 to 4903)
AUTHORS Shrivastav,A., Sharma,A.R., Bajaj,G., Charavaryamath,C., Ezzat,W.,
Spafford,P., Gore-Hickman,R., Singh,B., Copete,M.A. and Sharma,R.K.
TITLE Elevated N-myristoyltransferase activity and expression in oral
squamous cell carcinoma
JOURNAL Oncol. Rep. 18 (1), 93-97 (2007)
PUBMED 17549352
REMARK GeneRIF: Elevated N-myristoyltransferase activity is associated
with oral squamous cell carcinoma
REFERENCE 5 (bases 1 to 4903)
AUTHORS Shrivastav,A., Varma,S., Saxena,A., DeCoteau,J. and Sharma,R.K.
TITLE N-myristoyltransferase: a potential novel diagnostic marker for
colon cancer
JOURNAL J Transl Med 5, 58 (2007)
PUBMED 18021392
REMARK GeneRIF: N-myristoyltransferase may have a role in progression of
colonic neoplasms
Publication Status: Online-Only
REFERENCE 6 (bases 1 to 4903)
AUTHORS Duronio,R.J., Reed,S.I. and Gordon,J.I.
TITLE Mutations of human myristoyl-CoA:protein N-myristoyltransferase
cause temperature-sensitive myristic acid auxotrophy in
Saccharomyces cerevisiae
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 89 (9), 4129-4133 (1992)
PUBMED 1570339
REFERENCE 7 (bases 1 to 4903)
AUTHORS Wice,B.M. and Gordon,J.I.
TITLE A strategy for isolation of cDNAs encoding proteins affecting human
intestinal epithelial cell growth and differentiation:
characterization of a novel gut-specific N-myristoylated annexin
JOURNAL J. Cell Biol. 116 (2), 405-422 (1992)
PUBMED 1530946
REFERENCE 8 (bases 1 to 4903)
AUTHORS Pal,R., Reitz,M.S. Jr., Tschachler,E., Gallo,R.C.,
Sarngadharan,M.G. and Veronese,F.D.
TITLE Myristoylation of gag proteins of HIV-1 plays an important role in
virus assembly
JOURNAL AIDS Res. Hum. Retroviruses 6 (6), 721-730 (1990)
PUBMED 2194551
REFERENCE 9 (bases 1 to 4903)
AUTHORS Bryant,M. and Ratner,L.
TITLE Myristoylation-dependent replication and assembly of human
immunodeficiency virus 1
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87 (2), 523-527 (1990)
PUBMED 2405382
REFERENCE 10 (bases 1 to 4903)
AUTHORS Mumby,S.M., Heukeroth,R.O., Gordon,J.I. and Gilman,A.G.
TITLE G-protein alpha-subunit expression, myristoylation, and membrane
association in COS cells
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87 (2), 728-732 (1990)
PUBMED 2153964
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from BC006569.2.
On Dec 11, 2003 this sequence version replaced gi:20070182.
Summary: Myristate, a rare 14-carbon saturated fatty acid, is
cotranslationally attached by an amide linkage to the N-terminal
glycine residue of cellular and viral proteins with diverse
functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the
transfer of myristate from CoA to proteins. N-myristoylation
appears to be irreversible and is required for full expression of
the biologic activities of several N-myristoylated proteins,
including the alpha subunit of the signal-transducing guanine
nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311)
(Duronio et al., 1992 [PubMed 1570339]).[supplied by OMIM, Nov
2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC006538.2, AF043324.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025082 [ECO:0000348]
##Evidence-Data-END##
FEATURES Location/Qualifiers
source 1..4903
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17q21.31"
gene 1..4903
/gene="NMT1"
/gene_synonym="NMT"
/note="N-myristoyltransferase 1"
/db_xref="GeneID:4836"
/db_xref="HGNC:7857"
/db_xref="HPRD:01187"
/db_xref="MIM:160993"
exon 1..149
/gene="NMT1"
/gene_synonym="NMT"
/inference="alignment:Splign:1.39.8"
CDS 19..1509
/gene="NMT1"
/gene_synonym="NMT"
/EC_number="2.3.1.97"
/note="alternative, short form NMT-S; long form, NMT-L;
NMT 1; type I N-myristoyltransferase; peptide
N-myristoyltransferase 1; myristoyl-CoA:protein
N-myristoyltransferase 1"
/codon_start=1
/product="glycylpeptide N-tetradecanoyltransferase 1"
/protein_id="NP_066565.1"
/db_xref="GI:10835073"
/db_xref="CCDS:CCDS11494.1"
/db_xref="GeneID:4836"
/db_xref="HGNC:7857"
/db_xref="HPRD:01187"
/db_xref="MIM:160993"
/translation="
MADESETAVKPPAPPLPQMMEGNGNGHEHCSDCENEEDNSYNRGGLSPANDTGAKKKKKKQKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ
"
misc_feature 157..159
/gene="NMT1"
/gene_synonym="NMT"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(P30419.2); phosphorylation site"
misc_feature 157..159
/gene="NMT1"
/gene_synonym="NMT"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 157..159
/gene="NMT1"
/gene_synonym="NMT"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 274..1476
/gene="NMT1"
/gene_synonym="NMT"
/note="N-myristoyl transferase [Lipid metabolism]; Region:
NMT1; COG5092"
/db_xref="CDD:34695"
misc_feature 427..900
/gene="NMT1"
/gene_synonym="NMT"
/note="Myristoyl-CoA:protein N-myristoyltransferase,
N-terminal domain; Region: NMT; pfam01233"
/db_xref="CDD:110249"
misc_feature 556..558
/gene="NMT1"
/gene_synonym="NMT"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:00655"
misc_feature 556..558
/gene="NMT1"
/gene_synonym="NMT"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:01301"
misc_feature 940..1503
/gene="NMT1"
/gene_synonym="NMT"
/note="Myristoyl-CoA:protein N-myristoyltransferase,
C-terminal domain; Region: NMT_C; pfam02799"
/db_xref="CDD:202401"
variation 62
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:202061902"
variation 142..144
/gene="NMT1"
/gene_synonym="NMT"
/replace=""
/replace="aac"
/db_xref="dbSNP:375981533"
variation 147
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="g"
/db_xref="dbSNP:143955814"
exon 150..258
/gene="NMT1"
/gene_synonym="NMT"
/inference="alignment:Splign:1.39.8"
variation 166
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:140455291"
variation 199
/gene="NMT1"
/gene_synonym="NMT"
/replace="g"
/replace="t"
/db_xref="dbSNP:3087878"
variation 204
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:375158125"
variation 209
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:201559014"
variation 219
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:141656657"
variation 228
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:369434915"
variation 240
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:184508172"
exon 259..403
/gene="NMT1"
/gene_synonym="NMT"
/inference="alignment:Splign:1.39.8"
variation 263
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="t"
/db_xref="dbSNP:367954716"
variation 267
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:200633656"
variation 306
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:372318247"
variation 362
/gene="NMT1"
/gene_synonym="NMT"
/replace="g"
/replace="t"
/db_xref="dbSNP:377156745"
variation 398
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:144433221"
exon 404..522
/gene="NMT1"
/gene_synonym="NMT"
/inference="alignment:Splign:1.39.8"
variation 405
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="c"
/db_xref="dbSNP:199678185"
variation 429
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="g"
/db_xref="dbSNP:147841016"
variation 439
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:201386803"
variation 505
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1132898"
variation 511
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:149737135"
exon 523..614
/gene="NMT1"
/gene_synonym="NMT"
/inference="alignment:Splign:1.39.8"
variation 558
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:151247418"
STS 564..713
/gene="NMT1"
/gene_synonym="NMT"
/standard_name="MARC_16857-16858:1015861084:3"
/db_xref="UniSTS:268139"
variation 597
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="c"
/db_xref="dbSNP:372926712"
variation 600
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:146345914"
exon 615..731
/gene="NMT1"
/gene_synonym="NMT"
/inference="alignment:Splign:1.39.8"
variation 623
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:150418753"
variation 639
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:369385342"
variation 669
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:199671891"
variation 675
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:112989351"
variation 705
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="g"
/db_xref="dbSNP:375089291"
exon 732..902
/gene="NMT1"
/gene_synonym="NMT"
/inference="alignment:Splign:1.39.8"
variation 816
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:146578323"
variation 837
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:201216212"
variation 841
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:367724198"
variation 844
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:371122860"
variation 888
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:2239922"
variation 889
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:376218058"
exon 903..1011
/gene="NMT1"
/gene_synonym="NMT"
/inference="alignment:Splign:1.39.8"
variation 934
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:2239923"
exon 1012..1182
/gene="NMT1"
/gene_synonym="NMT"
/inference="alignment:Splign:1.39.8"
variation 1022
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:375623297"
variation 1052
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="c"
/db_xref="dbSNP:3194194"
variation 1111
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:148483868"
exon 1183..1350
/gene="NMT1"
/gene_synonym="NMT"
/inference="alignment:Splign:1.39.8"
variation 1185
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:142226258"
variation 1191
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:369014766"
variation 1290
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:143838999"
exon 1351..1488
/gene="NMT1"
/gene_synonym="NMT"
/inference="alignment:Splign:1.39.8"
variation 1360
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:1802201"
variation 1398
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="c"
/db_xref="dbSNP:376284001"
variation 1402
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:141629884"
variation 1404
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:372878120"
variation 1422
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:369290804"
variation 1458
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:373214072"
variation 1470
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:200139594"
exon 1489..4886
/gene="NMT1"
/gene_synonym="NMT"
/inference="alignment:Splign:1.39.8"
STS 1511..1778
/gene="NMT1"
/gene_synonym="NMT"
/standard_name="STS-M86707"
/db_xref="UniSTS:26977"
variation 1519..1520
/gene="NMT1"
/gene_synonym="NMT"
/replace=""
/replace="g"
/db_xref="dbSNP:371911420"
variation 1520
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:377286541"
variation 1524
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:370761943"
variation 1530
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:1053733"
variation 1551
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:371753337"
variation 1575
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:369051195"
variation 1579
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:374157641"
variation 1597
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:141202848"
variation 1610
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:1053739"
variation 1678
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:114271764"
variation 1692
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:143311253"
variation 1702
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:148324496"
STS 1710..1810
/gene="NMT1"
/gene_synonym="NMT"
/standard_name="SHGC-34291"
/db_xref="UniSTS:3300"
variation 1789
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:369699233"
variation 1829..1830
/gene="NMT1"
/gene_synonym="NMT"
/replace=""
/replace="ta"
/db_xref="dbSNP:199746970"
variation 1905
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:17684744"
variation 1922
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:16939858"
variation 2164
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:117105863"
variation 2215
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:376815066"
variation 2233
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:724329"
variation 2264
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="t"
/db_xref="dbSNP:141446378"
variation 2356
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="g"
/db_xref="dbSNP:180906761"
variation 2387
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="g"
/db_xref="dbSNP:28421762"
variation 2467
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:374822197"
variation 2549
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:187009810"
variation 2654
/gene="NMT1"
/gene_synonym="NMT"
/replace="g"
/replace="t"
/db_xref="dbSNP:16939861"
variation 2690
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:192258080"
variation 2742
/gene="NMT1"
/gene_synonym="NMT"
/replace="g"
/replace="t"
/db_xref="dbSNP:369197832"
variation 2803
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:370020780"
variation 2811
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:138084835"
variation 2874
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:35368650"
variation 2876
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="c"
/db_xref="dbSNP:374358296"
variation 3040
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="c"
/db_xref="dbSNP:12449780"
variation 3048
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:11548428"
variation 3129
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:143759450"
variation 3140
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:183449664"
variation 3208..3209
/gene="NMT1"
/gene_synonym="NMT"
/replace=""
/replace="c"
/db_xref="dbSNP:35225641"
variation 3525
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="c"
/db_xref="dbSNP:2269746"
STS 3546..4428
/gene="NMT1"
/gene_synonym="NMT"
/standard_name="NMT1_8508"
/db_xref="UniSTS:467801"
variation 3664
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:147214037"
variation 3682..3683
/gene="NMT1"
/gene_synonym="NMT"
/replace=""
/replace="ggg"
/db_xref="dbSNP:141401145"
variation 3715
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:140336433"
variation 3744
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="g"
/db_xref="dbSNP:1989802"
variation 3747
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:142694577"
STS 3778..3901
/gene="NMT1"
/gene_synonym="NMT"
/standard_name="RH70326"
/db_xref="UniSTS:46123"
variation 3800
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="g"
/db_xref="dbSNP:187295973"
variation 3802
/gene="NMT1"
/gene_synonym="NMT"
/replace=""
/replace="t"
/db_xref="dbSNP:3214106"
variation 3827
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:144416810"
variation 3870
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="g"
/db_xref="dbSNP:77946949"
variation 3905
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:190636525"
variation 3915
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:182422410"
variation 3929
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:188355789"
variation 3945
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:200266826"
variation 3946
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:148432087"
variation 3968
/gene="NMT1"
/gene_synonym="NMT"
/replace="g"
/replace="t"
/db_xref="dbSNP:142546587"
variation 3969
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:150884493"
variation 3994
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="g"
/db_xref="dbSNP:1989803"
variation 4002
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:1989804"
variation 4031..4032
/gene="NMT1"
/gene_synonym="NMT"
/replace=""
/replace="c"
/db_xref="dbSNP:34744705"
variation 4049
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:139674606"
variation 4061
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="c"
/db_xref="dbSNP:192155766"
STS 4070..4205
/gene="NMT1"
/gene_synonym="NMT"
/standard_name="RH66609"
/db_xref="UniSTS:26300"
variation 4159
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="g"
/db_xref="dbSNP:144545088"
variation 4183
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:12936003"
variation 4262
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:193078436"
variation 4322
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:2239925"
variation 4397
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:78867706"
variation 4487
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:368287374"
variation 4524
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="c"
/db_xref="dbSNP:184426663"
variation 4534
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:146633312"
variation 4556
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:12723"
variation 4614
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:116783088"
variation 4620
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:75772115"
variation 4656
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:187764117"
variation 4657
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="g"
/db_xref="dbSNP:376074145"
variation 4700
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:11548430"
STS 4725..4848
/gene="NMT1"
/gene_synonym="NMT"
/standard_name="WI-13574"
/db_xref="UniSTS:74772"
variation 4784
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="g"
/db_xref="dbSNP:192440480"
variation 4807
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:372498096"
variation 4849
/gene="NMT1"
/gene_synonym="NMT"
/replace="c"
/replace="t"
/db_xref="dbSNP:141266275"
variation 4878
/gene="NMT1"
/gene_synonym="NMT"
/replace="a"
/replace="t"
/db_xref="dbSNP:112206165"
ORIGIN
ctgctctcgcaactcaagatggcggacgagagtgagacagcagtgaagccgccggcacctccgctgccgcagatgatggaagggaacgggaacggccatgagcactgcagcgattgcgagaatgaggaggacaacagctacaaccggggtggtttgagtccagccaatgacactggagccaaaaagaagaaaaagaaacaaaaaaagaagaaagaaaaaggcagtgagacagattcagcccaggatcagcctgtgaagatgaactctttgccagcagagaggatccaggaaatacagaaggccattgagctgttctcagtgggtcagggacctgccaaaaccatggaggaggctagcaagcgaagctaccagttctgggatacgcagcccgtccccaagctgggcgaagtggtgaacacccatggccccgtggagcctgacaaggacaatatccgccaggagccctacaccctgccccagggcttcacctgggatgctttggacttgggcgatcgtggtgtgctaaaagaactgtacaccctcctgaatgagaactatgtggaagatgatgacaacatgttccgatttgattattccccggagtttcttttgtgggctctccggccacccggctggctcccccagtggcactgtggggttcgagtggtctcaagtcggaaattggttgggttcattagcgccatcccagcaaacatccatatctatgacacagagaagaagatggtagagatcaacttcctgtgtgtccacaagaagctgcgttccaagagggttgctccagttctgatccgagagatcaccaggcgggttcacctggagggcatcttccaagcagtttacactgccggggtggtactaccaaagcccgttggcacctgcaggtattggcatcggtccctaaacccacggaagctgattgaagtgaagttctcccacctgagcagaaatatgaccatgcagcgcaccatgaagctctaccgactgccagagactcccaagacagctgggctgcgaccaatggaaacaaaggacattccagtagtgcaccagctcctcaccaggtacttgaagcaatttcaccttacgcccgtcatgagccaggaggaggtggagcactggttctacccccaggagaatatcatcgacactttcgtggtggagaacgcaaacggagaggtgacagatttcctgagcttttatacgctgccctccaccatcatgaaccatccaacccacaagagtctcaaagctgcttattctttctacaacgttcacacccagacccctcttctagacctcatgagcgacgcccttgtcctcgccaaaatgaaagggtttgatgtgttcaatgcactggatctcatggagaacaaaaccttcctggagaagctcaagtttggcataggggacggcaacctgcagtattacctttacaattggaaatgccccagcatgggggcagagaaggttggactggtgctacaataaccagtcaccagtgcgattctggataaagccactgaaaattcgaaccaggaaatggaaccccaccactgttggtccaattttcacacacgtgagaatccctggcaaagggagcagaactgaaccggctttaccaaaccgccagcgaacttgacaattgtattgcgatggcgtgggctgcgtgacgtcacctccggtcgtgtctctggtctccgtgttttccagttaattacatcctcatgcagccgtgatcaagggaatgtaactgctgaaaactagctcgtgattggcatataatggagttaacgggtgaataataaaagtatatatatatattatatatatataaatattttaaatatctttcatgttccaaatgtacaaggatgtttggtctttaatgaaaagctgaatctagatcattcctcagaatgaggacccgaggacagtggcagacagacgcgttggcacagttcatggtttcctccagaggagacattggcttatcatggggaaaaagaggatctggagaacctcatccagctccccttctgaatcagctgggatgactggctttgagaaggaagggaagatggaacaggctcagatctcatgggatagcacgtggagctcttggctggggctgaccctgggcagggactttcctgcagggccagacctgcctgcattctgagacaaagcaatggacggtccgcagaagcagacctcattgattgagtcctttcttccatccccttggcctgctccctgtaggaagtcatcctgccaactgatttaaaagggctctttagccagttgttgccaaccttatagggatgagtcccctgtgagattttgcttttccactgcctgggatgatgcagtttgaagaggcccttggacctccttgtaacatcagggacctttggagaccattatcagtgtaagccctgcttagctcatcttagagcaaagagccagcaccctgatgtccctggggtggctaggcaggagtggcgtggggccaatacccagaccccttcagccaccagcccctggcctgtgccttccaacccattagccatttcttgttgtgcccctttccaagatacagcctgcaagtggtagcaagaagtgattagaggcagatctggacttggcaacagaagtggtttcccatctccattgtctgagtctgattttcgctgatgctgttttgtggatttttgtggtagtgatggttgtcagtgctgccagtttcccaaaacgtaatcaagcctctggtcacatggctgtcgatgtaggcattctggagtggtgttcagccaagtgaccgggcaaaattgggctgtgaaattgtacttccaggcttggatgtaatttttgctctagagagaagcaagtggtgggaaggaggtagcatgacgtgtggtgtgcgggtttccttgctgccgtcacctctccgctcatacaggaatgaagccttagccaggaggccaggctcagccctgtgccactcaccgaagccactttctacaggccagcaggggcttgttgcaggctgtgggttttggtgtggtttgtcagaggctaattctgcagagtttccaaaaccagaagacatcgtatgcttgggatgggggccgtgccacccgtgggaatgctgcccgctctgcagactgctgctagagccagcaactccactaaggtggattttcatcaggggcctgcagggccctcccttttcccattgttcctgcgctgcaaattgcaggccccagcaatcgtgactgacgtttgctccttgactccaagaaactgagaccaaagaagctgctgttcttagcaagatgcgcactgcattccacaggtgggaggagtcggagaggcaggggcttgctttgcagccccacagacaacagttgcacagtgcctcaagccccagagtggctcaccctgtccagacctttgaggatatcaaaggacaaagtgcccaagtctttcctaccttgggggaacctggaacttggaaaggctccctgtcctagtcttgatctgttctgggccaggtcccagcttgagctgcctctgagatttgggctgtgcggatctctggagtgagctctgtttcggttgacccaggtcatggaatggaaacggtgaggccccagtggctgttctggaagaaacagatctcctggcaaaggccccagcatctccctcactgaaaccaggtggccggctcctcggactctgctttatgttgcggtgagaactctgcccaggtgtgcagggtttggcttgtgggctgcttgctgctcatctgatttttgtcccagtagtccctgcgttcttcattcaaccccttctgggacttcagctcagagagcaccatcccgggggtcagggcctccccacaggagccctgcagtgtggtagcgccatggctgtctcaaaccaagcaaaggaaggaccctgaggccttcacgctaaccatcctcgagcaactgctgttggaaggcctccctgggcctggcccccaccctctgccacccagtcctcccagctgccatgtttcaaagacgacctttacctcctgcctttggattgactctgcatttgaccacggactccagtctgtgtgtagggagagagctgagtaggaggcctccactccggatcgaggcctgtatagggctcgtttccccacacatgcctatttctgaagaggcttctgtcttatttgaaggccagcccacacccagctactttaacaccaggtttatggaaaatgtcaggccttccccacaactcctgtctaactgctgtcgcccccctacttgctggctctcagaagcctaggggagtccctgtggtcctgaattctttccccaaagacgaccagcatttaaccaacctaagggcccaaaggccttggacaactgcatggagctgcactctaggagaaggaggggaaccagatgttagatcaggggagggagcaggagtgtccctcccgtcagtgcctacccacctgtgaggcagccttctgatggcctggcccaccttccccagaaccaggggaggcctgaggcttcagttttactctgctgcaaaatgaaggcgggcctgcaagccgactacacctacggaggctgttgaggacaatttcattccattaaattaaaaaatactgactggctggcaggcaggtgccatgtctgggaacagggacgggggagcttcacctttttgtcttggcttttctttgggctgtgggggggcatccatttccagggtcggggaggaaataccaaatgcattgttgttctgctcaatacatctcacttgtttctaataaagaaagcagctgaacaaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:4836 -> Molecular function: GO:0003824 [catalytic activity] evidence: TAS
GeneID:4836 -> Molecular function: GO:0004379 [glycylpeptide N-tetradecanoyltransferase activity] evidence: IEA
GeneID:4836 -> Biological process: GO:0001701 [in utero embryonic development] evidence: IEA
GeneID:4836 -> Biological process: GO:0006498 [N-terminal protein lipidation] evidence: NAS
GeneID:4836 -> Biological process: GO:0006499 [N-terminal protein myristoylation] evidence: NAS
GeneID:4836 -> Biological process: GO:0006915 [apoptotic process] evidence: TAS
GeneID:4836 -> Biological process: GO:0007603 [phototransduction, visible light] evidence: TAS
GeneID:4836 -> Biological process: GO:0009249 [protein lipoylation] evidence: TAS
GeneID:4836 -> Biological process: GO:0016032 [viral process] evidence: TAS
GeneID:4836 -> Biological process: GO:0016056 [rhodopsin mediated signaling pathway] evidence: TAS
GeneID:4836 -> Biological process: GO:0022400 [regulation of rhodopsin mediated signaling pathway] evidence: TAS
GeneID:4836 -> Biological process: GO:0097193 [intrinsic apoptotic signaling pathway] evidence: TAS
GeneID:4836 -> Biological process: GO:1900740 [positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway] evidence: TAS
GeneID:4836 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:4836 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:4836 -> Cellular component: GO:0005886 [plasma membrane] evidence: IDA
GeneID:4836 -> Cellular component: GO:0015629 [actin cytoskeleton] evidence: IDA
GeneID:4836 -> Cellular component: GO:0030054 [cell junction] evidence: IDA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_066565 -> EC 2.3.1.97
by
@meso_cacase at
DBCLS
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