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2020-10-24 05:56:46, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_020477               7754 bp    mRNA    linear   PRI 07-JUL-2013
DEFINITION  Homo sapiens ankyrin 1, erythrocytic (ANK1), transcript variant 2,
            mRNA.
ACCESSION   NM_020477
VERSION     NM_020477.2  GI:70780354
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7754)
  AUTHORS   Harder,M.N., Ribel-Madsen,R., Justesen,J.M., Sparso,T.,
            Andersson,E.A., Grarup,N., Jorgensen,T., Linneberg,A., Hansen,T.
            and Pedersen,O.
  TITLE     Type 2 diabetes risk alleles near BCAR1 and in ANK1 associate with
            decreased beta-cell function whereas risk alleles near ANKRD55 and
            GRB14 associate with decreased insulin sensitivity in the Danish
            Inter99 cohort
  JOURNAL   J. Clin. Endocrinol. Metab. 98 (4), E801-E806 (2013)
   PUBMED   23457408
  REMARK    GeneRIF: ANK1 rs516946 confers impaired insulin release.
REFERENCE   2  (bases 1 to 7754)
  AUTHORS   Stefanovic,M., Puchulu-Campanella,E., Kodippili,G. and Low,P.S.
  TITLE     Oxygen regulates the band 3-ankyrin bridge in the human erythrocyte
            membrane
  JOURNAL   Biochem. J. 449 (1), 143-150 (2013)
   PUBMED   23013433
  REMARK    GeneRIF: The ankyrin-binding site on band 3 is located near the
            deoxygenated hemoglobin-binding site, therefore following
            deoxygenation ankyrin is displaced from band 3.
REFERENCE   3  (bases 1 to 7754)
  AUTHORS   Yocum,A.O., Steiner,L.A., Seidel,N.E., Cline,A.P., Rout,E.D.,
            Lin,J.Y., Wong,C., Garrett,L.J., Gallagher,P.G. and Bodine,D.M.
  TITLE     A tissue-specific chromatin loop activates the erythroid ankyrin-1
            promoter
  JOURNAL   Blood 120 (17), 3586-3593 (2012)
   PUBMED   22968456
  REMARK    GeneRIF: A tissue-specific chromatin loop brings NF-E2 and ANK1E
            into close proximity preventing gene silencing and mutagenesis
            leading to hereditary spherocytosis.
REFERENCE   4  (bases 1 to 7754)
  AUTHORS   Imamura M, Maeda S, Yamauchi T, Hara K, Yasuda K, Morizono T,
            Takahashi A, Horikoshi M, Nakamura M, Fujita H, Tsunoda T, Kubo M,
            Watada H, Maegawa H, Okada-Iwabu M, Iwabu M, Shojima N, Ohshige T,
            Omori S, Iwata M, Hirose H, Kaku K, Ito C, Tanaka Y, Tobe K,
            Kashiwagi A, Kawamori R, Kasuga M, Kamatani N, Nakamura Y and
            Kadowaki T.
  CONSRTM   Diabetes Genetics Replication and Meta-analysis (DIAGRAM)
            Consortium
  TITLE     A single-nucleotide polymorphism in ANK1 is associated with
            susceptibility to type 2 diabetes in Japanese populations
  JOURNAL   Hum. Mol. Genet. 21 (13), 3042-3049 (2012)
   PUBMED   22456796
  REMARK    GeneRIF: results indicate that the ANK1 locus is a new, common
            susceptibility locus for type 2 diabetes across different ethnic
            groups
REFERENCE   5  (bases 1 to 7754)
  AUTHORS   Lange,S., Perera,S., Teh,P. and Chen,J.
  TITLE     Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1
            (sAnk1.5) protein turnover
  JOURNAL   Mol. Biol. Cell 23 (13), 2490-2504 (2012)
   PUBMED   22573887
  REMARK    GeneRIF: The interaction of KCTD6 with ankyrin-1 may have
            implications beyond muscle for hereditary spherocytosis, as KCTD6
            is also present in erythrocytes, and erythrocyte ankyrin isoforms
            contain its mapped minimal binding site.
REFERENCE   6  (bases 1 to 7754)
  AUTHORS   Fujimoto,T., Lee,K., Miwa,S. and Ogawa,K.
  TITLE     Immunocytochemical localization of fodrin and ankyrin in bovine
            chromaffin cells in vitro
  JOURNAL   J. Histochem. Cytochem. 39 (11), 1485-1493 (1991)
   PUBMED   1833445
REFERENCE   7  (bases 1 to 7754)
  AUTHORS   Lux,S.E., John,K.M. and Bennett,V.
  TITLE     Analysis of cDNA for human erythrocyte ankyrin indicates a repeated
            structure with homology to tissue-differentiation and cell-cycle
            control proteins
  JOURNAL   Nature 344 (6261), 36-42 (1990)
   PUBMED   2137557
REFERENCE   8  (bases 1 to 7754)
  AUTHORS   Lambert,S., Yu,H., Prchal,J.T., Lawler,J., Ruff,P., Speicher,D.,
            Cheung,M.C., Kan,Y.W. and Palek,J.
  TITLE     cDNA sequence for human erythrocyte ankyrin
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 87 (5), 1730-1734 (1990)
   PUBMED   1689849
REFERENCE   9  (bases 1 to 7754)
  AUTHORS   Bennett,V.
  TITLE     Immunoreactive forms of human erythrocyte ankyrin are present in
            diverse cells and tissues
  JOURNAL   Nature 281 (5732), 597-599 (1979)
   PUBMED   492324
REFERENCE   10 (bases 1 to 7754)
  AUTHORS   Bennett,V. and Stenbuck,P.J.
  TITLE     The membrane attachment protein for spectrin is associated with
            band 3 in human erythrocyte membranes
  JOURNAL   Nature 280 (5722), 468-473 (1979)
   PUBMED   379653
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from X16609.1, AB209418.1, M28880.1,
            AK126647.1, AC113133.5 and N63745.1.
            On Jul 13, 2005 this sequence version replaced gi:10947041.
            
            Summary: Ankyrins are a family of proteins that link the integral
            membrane proteins to the underlying spectrin-actin cytoskeleton and
            play key roles in activities such as cell motility, activation,
            proliferation, contact and the maintenance of specialized membrane
            domains. Multiple isoforms of ankyrin with different affinities for
            various target proteins are expressed in a tissue-specific,
            developmentally regulated manner. Most ankyrins are typically
            composed of three structural domains: an amino-terminal domain
            containing multiple ankyrin repeats; a central region with a highly
            conserved spectrin binding domain; and a carboxy-terminal
            regulatory domain which is the least conserved and subject to
            variation. Ankyrin 1, the prototype of this family, was first
            discovered in the erythrocytes, but since has also been found in
            brain and muscles. Mutations in erythrocytic ankyrin 1 have been
            associated in approximately half of all patients with hereditary
            spherocytosis. Complex patterns of alternative splicing in the
            regulatory domain, giving rise to different isoforms of ankyrin 1
            have been described. Truncated muscle-specific isoforms of ankyrin
            1 resulting from usage of an alternate promoter have also been
            identified. [provided by RefSeq, Dec 2008].
            
            Transcript Variant: This variant (2) lacks an in-frame segment near
            to the 3' coding region, compared to variant 1. The resulting
            isoform (2, also referred to as isoform 2.2) is therefore shorter
            than isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed/partial sample support ERS025081, ERS025082
                              [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-398               X16609.1           1-398
            399-400             AB209418.1         696-697
            401-2156            X16609.1           401-2156
            2157-2158           M28880.1           2157-2158
            2159-2545           X16609.1           2159-2545
            2546-2996           AK126647.1         426-876
            2997-2998           M28880.1           2997-2998
            2999-5076           AK126647.1         879-2956
            5077-5841           X16609.1           5563-6327
            5842-7745           AC113133.5         6261-8164           c
            7746-7754           N63745.1           1-9                 c
FEATURES             Location/Qualifiers
     source          1..7754
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8p11.1"
     gene            1..7754
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="ankyrin 1, erythrocytic"
                     /db_xref="GeneID:286"
                     /db_xref="HGNC:492"
                     /db_xref="MIM:612641"
     exon            1..111
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    73..75
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="upstream in-frame stop codon"
     CDS             85..5244
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="isoform 2 is encoded by transcript variant 2;
                     ankyrin-R; ankyrin-1; ANK-1; erythrocyte ankyrin"
                     /codon_start=1
                     /product="ankyrin-1 isoform 2"
                     /protein_id="NP_065210.2"
                     /db_xref="GI:70780355"
                     /db_xref="GeneID:286"
                     /db_xref="HGNC:492"
                     /db_xref="MIM:612641"
                     /translation="
MPYSVGFREADAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVLVSDKHRMSFPETVDEILDVSEDEGEELISFKAERRDSRDVDEEKELLDFVPKLDQVVESPAIPRIPCAMPETVVIRSEEQEQASKEYDEDSLIPSSPATETSDNISPVASPVHTGFLVSFMVDARGGSMRGSRHNGLRVVIPPRTCAAPTRITCRLVKPQKLSTPPPLAEEEGLASRIIALGPTGAQFLSPVIVEIPHFASHGRGDRELVVLRSENGSVWKEHRSRYGESYLDQILNGMDEELGSLEELEKKRVCRIITTDFPLYFVIMSRLCQDYDTIGPEGGSLKSKLVPLVQATFPENAVTKRVKLALQAQPVPDELVTKLLGNQATFSPIVTVEPRRRKFHRPIGLRIPLPPSWTDNPRDSGEGDTTSLRLLCSVIGGTDQAQWEDITGTTKLVYANECANFTTNVSARFWLSDCPRTAEAVNFATLLYKELTAVPYMAKFVIFAKMNDPREGRLRCYCMTDDKVDKTLEQHENFVEVARSRDIEVLEGMSLFAELSGNLVPVKKAAQQRSFHFQSFRENRLAMPVKVRDSSREPGGSLSFLRKAMKYEDTQHILCHLNITMPPCAKGSGAEDRRRTPTPLALRYSILSESTPGSLSGTEQAEMKMAVISEHLGLSWAELARELQFSVEDINRIRVENPNSLLEQSVALLNLWVIREGQNANMENLYTALQSIDRGEIVNMLEGSGRQSRNLKPDRRHTDRDYSLSPSQMNGHQRGQARITHSPTVSQVTERSQDRLQDWDADGSIVSYLQDAAQGSWQEEVTQGPHSFQGTSTMTEGLEPGGSQEYEKVLVSVSEHTWTEQPEAESSQADRDRRQQGQEEQVQEAKNTFTQVVQGNEFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEVTVEGPLEDPSELEVDIDYFMKHSKDHTSTPNP
"
     misc_feature    85..2565
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (P16157.3);
                     Region: 89 kDa domain"
     misc_feature    124..279
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (many copies); Region: Ank_4;
                     pfam13637"
                     /db_xref="CDD:205814"
     misc_feature    199..576
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="ankyrin repeats;  ankyrin repeats mediate
                     protein-protein interactions in very diverse families of
                     proteins. The number of ANK repeats in a protein can range
                     from 2 to over 20 (ankyrins, for example). ANK repeats may
                     occur in combinations with other...; Region: ANK; cd00204"
                     /db_xref="CDD:29261"
     misc_feature    229..501
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:205076"
     misc_feature    397..399
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="(3S)-3-hydroxyasparagine, by HIF1AN, partial;
                     propagated from UniProtKB/Swiss-Prot (P16157.3);
                     hydroxylation site"
     misc_feature    613..888
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:205076"
     misc_feature    682..1059
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="ankyrin repeats;  ankyrin repeats mediate
                     protein-protein interactions in very diverse families of
                     proteins. The number of ANK repeats in a protein can range
                     from 2 to over 20 (ankyrins, for example). ANK repeats may
                     occur in combinations with other...; Region: ANK; cd00204"
                     /db_xref="CDD:29261"
     misc_feature    781..783
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="(3S)-3-hydroxyasparagine, by HIF1AN, partial;
                     propagated from UniProtKB/Swiss-Prot (P16157.3);
                     hydroxylation site"
     misc_feature    811..1080
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:205076"
     misc_feature    1009..1284
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:205076"
     misc_feature    1078..1455
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="ankyrin repeats;  ankyrin repeats mediate
                     protein-protein interactions in very diverse families of
                     proteins. The number of ANK repeats in a protein can range
                     from 2 to over 20 (ankyrins, for example). ANK repeats may
                     occur in combinations with other...; Region: ANK; cd00204"
                     /db_xref="CDD:29261"
     misc_feature    1294..1455
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (many copies); Region: Ank_4;
                     pfam13637"
                     /db_xref="CDD:205814"
     misc_feature    1375..1377
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="(3S)-3-hydroxyasparagine, by HIF1AN, partial;
                     propagated from UniProtKB/Swiss-Prot (P16157.3);
                     hydroxylation site"
     misc_feature    1405..1665
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:205076"
     misc_feature    1474..1476
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="(3S)-3-hydroxyasparagine, by HIF1AN, partial;
                     propagated from UniProtKB/Swiss-Prot (P16157.3);
                     hydroxylation site"
     misc_feature    1489..1851
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="ankyrin repeats;  ankyrin repeats mediate
                     protein-protein interactions in very diverse families of
                     proteins. The number of ANK repeats in a protein can range
                     from 2 to over 20 (ankyrins, for example). ANK repeats may
                     occur in combinations with other...; Region: ANK; cd00204"
                     /db_xref="CDD:29261"
     misc_feature    1603..1872
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:205076"
     misc_feature    1771..2148
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="ankyrin repeats;  ankyrin repeats mediate
                     protein-protein interactions in very diverse families of
                     proteins. The number of ANK repeats in a protein can range
                     from 2 to over 20 (ankyrins, for example). ANK repeats may
                     occur in combinations with other...; Region: ANK; cd00204"
                     /db_xref="CDD:29261"
     misc_feature    1888..2049
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (many copies); Region: Ank_4;
                     pfam13637"
                     /db_xref="CDD:205814"
     misc_feature    1969..2346
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="ankyrin repeats;  ankyrin repeats mediate
                     protein-protein interactions in very diverse families of
                     proteins. The number of ANK repeats in a protein can range
                     from 2 to over 20 (ankyrins, for example). ANK repeats may
                     occur in combinations with other...; Region: ANK; cd00204"
                     /db_xref="CDD:29261"
     misc_feature    1969..1971
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="(3S)-3-hydroxyasparagine, by HIF1AN, partial;
                     propagated from UniProtKB/Swiss-Prot (P16157.3);
                     hydroxylation site"
     misc_feature    1999..2274
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:205076"
     misc_feature    2068..2070
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="(3S)-3-hydroxyasparagine, by HIF1AN, partial;
                     propagated from UniProtKB/Swiss-Prot (P16157.3);
                     hydroxylation site"
     misc_feature    2167..2169
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="(3S)-3-hydroxyaspartate, by HIF1AN, partial;
                     propagated from UniProtKB/Swiss-Prot (P16157.3);
                     hydroxylation site"
     misc_feature    2242..2406
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (many copies); Region: Ank_5;
                     pfam13857"
                     /db_xref="CDD:206028"
     misc_feature    2266..2268
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="(3S)-3-hydroxyasparagine, by HIF1AN, partial;
                     propagated from UniProtKB/Swiss-Prot (P16157.3);
                     hydroxylation site"
     misc_feature    2365..2367
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="(3S)-3-hydroxyasparagine, by HIF1AN, partial;
                     propagated from UniProtKB/Swiss-Prot (P16157.3);
                     hydroxylation site"
     misc_feature    2815..3129
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Domain present in ZO-1 and Unc5-like netrin
                     receptors; Region: ZU5; smart00218"
                     /db_xref="CDD:128514"
     misc_feature    3784..4170
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (P16157.3);
                     Region: UPA domain (By similarity)"
     misc_feature    4285..4536
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Death domain of Ankyrin-1; Region: Death_ank1;
                     cd08805"
                     /db_xref="CDD:176783"
     exon            112..213
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            214..312
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            313..411
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       399
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2304871"
     exon            412..510
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            511..696
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       573
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34173100"
     variation       681
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2304873"
     exon            697..795
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            796..894
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            895..993
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            994..1191
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            1192..1290
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            1291..1389
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            1390..1488
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            1489..1686
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       1590
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34387324"
     exon            1687..1785
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            1786..1884
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            1885..2082
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       1940
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2304877"
     exon            2083..2181
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       2157
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1137177"
     exon            2182..2280
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            2281..2379
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       2295
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:34194642"
     exon            2380..2472
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       2433
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2304880"
     exon            2473..2545
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            2546..2642
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       2579
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:34523608"
     exon            2643..2721
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            2722..2819
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            2820..3044
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       2914
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:35797405"
     variation       2997
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:504574"
     variation       3030
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1137178"
     exon            3045..3199
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       3054
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34969689"
     exon            3200..3411
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       3308
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35213384"
     exon            3412..3616
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       3460
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:504465"
     variation       3570
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35964634"
     exon            3617..3713
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       3658
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:486770"
     exon            3714..3942
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            3943..4068
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            4069..4188
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            4189..4267
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            4268..4342
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            4343..4474
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       4469
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34664882"
     exon            4475..4621
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       4590
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34265667"
     exon            4622..4694
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            4695..4992
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            4993..5076
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            5077..5217
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       5150
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1060131"
     variation       5153
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1060132"
     variation       5169
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1060133"
     variation       5170
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1060134"
     variation       5178
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1060135"
     variation       5180
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1060136"
     variation       5181
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1060137"
     variation       5185
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1060138"
     variation       5189
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1060139"
     variation       5191
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1060140"
     variation       5202
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1137192"
     variation       5206
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1137194"
     variation       5208
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3208120"
     exon            5218..7746
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     STS             5363..5638
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /standard_name="SHGC-132081"
                     /db_xref="UniSTS:170634"
     STS             5374..5637
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /standard_name="RH69660"
                     /db_xref="UniSTS:24338"
     variation       5651
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201295961"
     STS             5790..5895
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /standard_name="GDB:178523"
                     /db_xref="UniSTS:66432"
     STS             5791..5976
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /standard_name="D8S2329"
                     /db_xref="UniSTS:31321"
     STS             6139..6471
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /standard_name="SHGC-12309"
                     /db_xref="UniSTS:21118"
     polyA_signal    6251..6256
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
     polyA_site      6279
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /experiment="experimental evidence, no additional details
                     recorded"
     variation       6751..6752
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:517309"
     variation       7333
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:543817"
     STS             7361..7527
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /standard_name="RH91316"
                     /db_xref="UniSTS:91775"
     polyA_signal    7724..7729
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
     polyA_site      7746
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
ORIGIN      
agaggctgcggtgagtccgccagccccagctgctcctcctcaagcccccaaggcccttcggcgggcccctgctgaaagaccggcatgccctattctgtgggcttccgcgaagccgatgctgctaccagctttctgagagcagcaagatcaggtaacttggacaaagctttggatcacctgcggaatggggtagatattaacacctgtaaccagaatgggttgaatggcttgcatctggcttctaaggaaggccatgtgaaaatggtggttgaacttctgcacaaagaaatcattctagaaacgacaaccaagaaggggaacacggccctgcacatcgctgctctagccgggcaggatgaggtggtccgggagcttgtcaactatggagccaacgtcaacgcccagtcacagaaaggttttacacccctgtacatggcagcacaagagaaccacttggaagtggttaagtttttactggaaaatggagctaaccagaatgtagccacagaagacggcttcacgcctctggcggtagccctgcagcagggccatgagaacgtcgtcgcgcacctcatcaactacggcaccaaggggaaggtgcgcctcccggccctgcacatcgcggcccgcaacgacgacacgcgcacggctgcggtgctgctgcagaacgaccccaacccggacgtgctttccaagacgggattcacgcccctgcacattgcggctcactacgagaacctcaacgtggcccagttgctcctcaacagaggagccagcgtcaatttcacaccacagaacggcatcacgccactgcacatcgcctcccgcaggggcaacgtgatcatggtgcggctgctgctggatcggggagcccagatagaaaccaagaccaaggacgaattgacacctctccactgtgcagctcgaaatgggcacgtgcgaatctcagagatcctgctggaccacggggcaccaatccaagccaaaaccaagaacggcctgtccccaattcacatggcggctcagggagaccacctcgactgtgtccggctcctgttgcaatacgacgcagagatagacgacatcaccctggaccacctgaccccactccacgtggctgcccactgtggacaccacagggtggctaaggtccttctggataaaggggccaaacccaactccagagccctgaatggctttacccccttacacatcgcctgcaaaaagaaccacgtccgtgtcatggagctgctgctgaagacgggagcctcgatcgacgcggtcaccgagtctggcctgacacctctccacgtggcctccttcatggggcaccttcccatcgtgaagaacctcctgcagcggggggcgtcgcccaacgtctccaacgtgaaagtggagaccccgctacacatggcagccagagccgggcacacggaagtggccaaatatttactccagaacaaagccaaagtcaatgccaaggccaaggatgaccagaccccacttcactgtgcagctcgcatcggccacacaaacatggtgaagctcctgctggaaaataacgccaaccccaacctggccaccaccgccgggcacacccccctgcacattgcagcccgtgagggccatgtggaaacagtcctggcccttctggaaaaggaagcatcccaggcctgcatgaccaagaaaggatttacccctctgcacgtggcggccaagtacgggaaggtgcgggtggcagagctgctgctggagcgggacgcacacccgaatgctgccggaaaaaatggcctgacccccctgcacgtggccgtccatcacaacaacctggacatcgtcaagctgctgcttccccggggcggctccccgcacagccctgcctggaatggctacacccctttgcacatcgctgccaagcagaaccaggtggaggtggcccgtagtctgctgcagtatgggggctcagcaaacgccgagtcggtgcaaggtgtgacgccccttcacctggccgcccaggagggccacgcagagatggtggctctgctgctctcgaaacaagccaatggcaacctggggaacaagagcggactcactcccctccatctggtagcacaagaaggccacgttccagtggcagatgtgctgatcaaacacggcgtcatggtggacgccaccacccggatgggctacactcccctccatgtggccagtcactatggaaacatcaagctggtgaagtttctgctgcagcaccaggcagatgtcaatgccaagaccaagctaggatacagccccctgcaccaggcagcccagcagggacacacagacatcgtgactctgcttctgaaaaacggtgcttccccaaacgaggtcagctcggatggaaccacacctctggccatagccaagcgcttgggctacatttctgtcaccgacgtgctcaaggtcgtcacggatgaaaccagtttcgtgttagtcagtgataagcatcgaatgagtttccctgagacagttgatgagatcctggatgtctcggaagatgaaggggaagaactcatcagcttcaaggctgagaggcgggattccagggatgttgatgaagagaaggagctgctggattttgtgccgaagctagaccaagtggtggaatctccagccatccccaggattccctgtgccatgcctgagacagtggtgatcaggtcagaagagcaggagcaggcatctaaagagtatgatgaggactccctcatccccagcagcccggccaccgagacctcagacaacatcagcccggtggccagcccggtgcatacagggtttctggtgagcttcatggttgacgcccggggtggttccatgagaggaagtcgccacaacggcctgcgagtggtgatcccgccacggacgtgcgcagcgcccacccgcatcacctgccgcctggtcaagccccagaagctcagcacgccgcccccactggccgaggaggagggcctggccagcaggatcatagcactggggcccacgggggcacagttcctgagccctgtaatcgtggagatcccgcactttgcctcccatggccgtggagaccgcgagctcgtggttctgaggagcgaaaacggctccgtgtggaaggagcacaggagccgctatggagagagctacctggatcagatcctcaacgggatggacgaagagctggggagcctggaggagctagagaagaagagggtgtgccgaatcatcaccaccgacttcccgctgtacttcgtgatcatgtcacggctctgccaggactacgacaccatcggtcccgaagggggctccctgaagagcaagctggtgcccctggtacaggcaacgttcccggagaatgccgtcaccaagagagtgaagctggctctgcaggcccagcctgtcccggatgagcttgtcactaagctcctgggcaaccaggccacattcagccccattgtcaccgtggagccccggcgccggaagttccaccgccccattgggcttcggatcccactacctccttcctggaccgacaacccgagggacagcggggagggagacaccaccagcctgcgcctgctttgcagcgtcattggaggaacagaccaagcccagtgggaagacataacaggaaccaccaaacttgtatatgccaacgagtgcgccaacttcaccaccaatgtctctgccaggttttggctgtcggactgtcctcggactgctgaggctgtgaactttgccaccctgctgtacaaagagctcactgcagtgccctacatggccaaattcgtcatctttgccaagatgaatgacccccgagaggggcgcctgcgctgctactgcatgacagatgataaagtggacaagaccctggagcagcatgagaacttcgtggaggtggcccggagcagggacatagaggtgttggaaggaatgtccctgtttgcagaactctctgggaacctggtgcctgtgaagaaagctgcccagcagcggagcttccacttccagtcatttcgggagaaccgtctggccatgcctgtaaaggtgagggacagcagtcgagagccgggagggtccctgtcgtttctgcgcaaggcgatgaagtacgaggacacccagcacattctctgccacctgaacatcaccatgcccccctgcgccaagggaagtggagccgaagataggagaaggaccccgacgcccctggccctgcgatacagcattctcagtgagtccacaccaggttctctcagtgggacagagcaggcagagatgaagatggctgttatctcagagcacctcggtctcagctgggcagagttggcccgggagctgcagttcagtgtggaagacatcaacaggatccgagtggaaaatcccaactccctgttggagcagagtgtggccttgctgaacctctgggtcatccgtgaaggccaaaacgcaaacatggagaatctgtacacagccctgcagagcattgaccgtggcgagatcgtgaacatgctggagggttccggccgacagagccgcaacttgaagccagacaggcggcacaccgaccgcgactactcgctgtcaccctcccagatgaatggccatcagagggggcaagcccgaatcacacattcccccaccgtgagtcaggtgacggagaggagtcaggacagactgcaggactgggatgcagacggctcgattgtctcatacctgcaagatgctgcacaaggttcctggcaagaggaggtcacgcaaggtccacactcattccagggaacaagtaccatgactgaagggctagagcccggtggatctcaggagtacgagaaggtcctggtgtctgtaagtgagcacacgtggacagaacagcccgaggctgagagctcccaggccgacagggaccggaggcagcaaggccaagaagagcaggtgcaggaggccaagaacaccttcacccaagtggtgcaggggaatgagtttcagaatattccaggggagcaggtgacagaggagcaattcacggatgagcagggcaacattgtcaccaagaagatcattcgcaaggtggttcgacagatagacttgtccagcgccgatgccgcccaggagcacgaggaggtgactgtagaggggcccctggaggatcccagtgagctggaggtcgatattgattactttatgaaacactccaaggatcacacctcgacacccaacccctgaaccccacacactctgccatgcacacaggaggagagctggacctgagggccaccgcagcggtgcacacattcctctgggctgacggcatgacctctgtaagggactcctgctagtcccctcttggcatgaatgactgactgtagacgcatgacctccaggcttcaatcctgcctcttgcaatgacagctgatctgtcggaaccaggacacaaaagcagcaagaagcggggagagagagggatagaaaacaagcgcaggagagcctgcgaacgcaaaagtgaatgagggctttttgtggctggggatgggttttggttttggggttttttttttaaattgttttgacttcgtacagggtactttttcccaacctcatctgtcagaaatccatgtgggcttcctggaaagaaaaaaaaaaaaaagaaaactaggcatgaaatcagtttaacaccttaatcttaagccatgtcctcatctgcccaccctccccaacccacatacctccattccacttgtgacaccccctcgactccctggtgacgctcctcccagatcgctctacatgacattcaggacacacacacacacacacacacaccactcgcctccactgaatctacacacagattttactgtgacttctgaagctgtatagactctgctgtggataaattggaattttttatgttgtctctctctctgccaatttcaatacgaatcatcttccaatggaaaatcattaccttgaagagtgcattcggggttccttgtgttagggacttaagaatctgaggcgaggacccccaggcttacctgtaggactcaaagggagccaggaccccatctgaaagggtctcctctctcagttgggggacaggccggtggctgacccaggattgcaccagcatgtccatagagaagaggttttctatgtcttcaagcactatatcatagtccgtgttcaaagtgtaaactgtacagtaatcagccttgtgtatatgaaaaacaataaatactatgcaaaccaatagaaacatttagcagtacgtacagagcctgacagcgcagctcctgaggacttctgcggctgcaggagaaggagctgtggcctgtctttcagtgaaagaggaaggaaaggagtagggctagtgaatgtatctgccaggtcttagaagtcaggaccacccagggtctcccagagtgaacttggtgctctaagtccaggcagcctgcaggctggggaccctgggtgcaggtgccaggctcgaggctgttccctgtcctgcctcagtgcctcccctctgcccagcccctgtggcctcttggagaggcgagccagggggctccccggaccgcatggccggtgagagtagagtcggaggcggagagcctggacgcccagaggccggggccaggctctgggtcaaggcaggaaggagacagacagctggcagttcctcgcctcggtgccatcagggaggagccttaagttccactagagcctccggcccagggaggccagaatcagcacaatcccggccccgccctcgcggcgggcgcccccagggccaggagagagagacagggctggctcctctcgcccctggagccgcggtgtggacggcccggccccgtccgccccgccgctctgcgggagtgtcctcgggacacacttaaaccttccaagtagcacagaagccccctccacgtcagaggccccctggccgcggggcctgtgagcggagaggggccctgcttcccacacaaatccgccccggtgcacccccggccaggcaggccccggggcggcctaggcgccttgtcggccgggggtggggctgcttttgcttcctttagaggggcgggcagggagaggaagctctagctccgggcctgagtttccccgaggctgcgtcggaggagctgcagggcgagcccggacggctgccgtctccgccagaggccaccccggcccggcctccagggcgcagaggcgcccccctccatcctcccccatcccgggggccacggcaggggggccgcacagcgcggctgggaccgattcggtgacggcccaaggaagctgggctcagggctcgcctctcccgcctcgatcctgcaccttcctctcccaggtcgctgctgcagccaacccagtagcccccttagcgcccccgcggaccccgcagctccagactccgctttggcacctctgctccggctggcatggctgcacgctccggctgctagtaggagccgttaggggaggagtttggggtctccacacgatgcctagagaatgctgcagtctgcacattagacgctttttagaagttttgaaattaccttgatttttttaattgttatgaaaatggatcttttcttgactctcccacatgctctgttatgggagagaatcccctaccctactctgatgtatagaccattctcccttcaccagccgaaccaatgtcaaaattaataaagaaatggactaatggcaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:286 -> Molecular function: GO:0005198 [structural molecule activity] evidence: NAS
            GeneID:286 -> Molecular function: GO:0005200 [structural constituent of cytoskeleton] evidence: TAS
            GeneID:286 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:286 -> Molecular function: GO:0008093 [cytoskeletal adaptor activity] evidence: IDA
            GeneID:286 -> Molecular function: GO:0008093 [cytoskeletal adaptor activity] evidence: TAS
            GeneID:286 -> Molecular function: GO:0019899 [enzyme binding] evidence: IPI
            GeneID:286 -> Molecular function: GO:0019899 [enzyme binding] evidence: TAS
            GeneID:286 -> Molecular function: GO:0030507 [spectrin binding] evidence: IDA
            GeneID:286 -> Molecular function: GO:0030507 [spectrin binding] evidence: IPI
            GeneID:286 -> Molecular function: GO:0030507 [spectrin binding] evidence: NAS
            GeneID:286 -> Molecular function: GO:0051117 [ATPase binding] evidence: IPI
            GeneID:286 -> Biological process: GO:0006779 [porphyrin-containing compound biosynthetic process] evidence: IEA
            GeneID:286 -> Biological process: GO:0006887 [exocytosis] evidence: NAS
            GeneID:286 -> Biological process: GO:0006888 [ER to Golgi vesicle-mediated transport] evidence: IDA
            GeneID:286 -> Biological process: GO:0007010 [cytoskeleton organization] evidence: NAS
            GeneID:286 -> Biological process: GO:0007165 [signal transduction] evidence: IEA
            GeneID:286 -> Biological process: GO:0007411 [axon guidance] evidence: TAS
            GeneID:286 -> Biological process: GO:0015672 [monovalent inorganic cation transport] evidence: IEA
            GeneID:286 -> Biological process: GO:0045199 [maintenance of epithelial cell apical/basal polarity] evidence: TAS
            GeneID:286 -> Biological process: GO:0048821 [erythrocyte development] evidence: IEA
            GeneID:286 -> Biological process: GO:0072661 [protein targeting to plasma membrane] evidence: IMP
            GeneID:286 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:286 -> Cellular component: GO:0005856 [cytoskeleton] evidence: NAS
            GeneID:286 -> Cellular component: GO:0005886 [plasma membrane] evidence: IDA
            GeneID:286 -> Cellular component: GO:0005886 [plasma membrane] evidence: NAS
            GeneID:286 -> Cellular component: GO:0014731 [spectrin-associated cytoskeleton] evidence: IDA
            GeneID:286 -> Cellular component: GO:0016323 [basolateral plasma membrane] evidence: NAS
            GeneID:286 -> Cellular component: GO:0016529 [sarcoplasmic reticulum] evidence: IEA
            GeneID:286 -> Cellular component: GO:0030863 [cortical cytoskeleton] evidence: IEA
            GeneID:286 -> Cellular component: GO:0031430 [M band] evidence: IEA

by @meso_cacase at DBCLS
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