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2024-04-26 11:22:02, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_019080 4666 bp mRNA linear PRI 15-JUN-2013
DEFINITION Homo sapiens Nedd4 family interacting protein 2 (NDFIP2),
transcript variant 1, mRNA.
ACCESSION NM_019080 XM_041162
VERSION NM_019080.2 GI:239046737
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4666)
CONSRTM GENDEP Investigators; MARS Investigators; STAR*D Investigators
TITLE Common genetic variation and antidepressant efficacy in major
depressive disorder: a meta-analysis of three genome-wide
pharmacogenetic studies
JOURNAL Am J Psychiatry 170 (2), 207-217 (2013)
PUBMED 23377640
REFERENCE 2 (bases 1 to 4666)
AUTHORS Mund,T. and Pelham,H.R.
TITLE Regulation of PTEN/Akt and MAP kinase signaling pathways by the
ubiquitin ligase activators Ndfip1 and Ndfip2
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 107 (25), 11429-11434 (2010)
PUBMED 20534535
REMARK GeneRIF: PTEN/Akt and MAP kinase signaling pathways are regulated
by the ubiquitin ligase activators Ndfip1 and Ndfip2
REFERENCE 3 (bases 1 to 4666)
AUTHORS Low,S.K., Kuchiba,A., Zembutsu,H., Saito,A., Takahashi,A., Kubo,M.,
Daigo,Y., Kamatani,N., Chiku,S., Totsuka,H., Ohnami,S., Hirose,H.,
Shimada,K., Okusaka,T., Yoshida,T., Nakamura,Y. and Sakamoto,H.
TITLE Genome-wide association study of pancreatic cancer in Japanese
population
JOURNAL PLoS ONE 5 (7), E11824 (2010)
PUBMED 20686608
REMARK Publication Status: Online-Only
REFERENCE 4 (bases 1 to 4666)
AUTHORS Mund,T. and Pelham,H.R.
TITLE Control of the activity of WW-HECT domain E3 ubiquitin ligases by
NDFIP proteins
JOURNAL EMBO Rep. 10 (5), 501-507 (2009)
PUBMED 19343052
REMARK GeneRIF: Data show that the small PY-containing membrane proteins,
NDFIP1 and NDFIP2 (NEDD4 family-interacting proteins), activate the
catalytic activity of ITCH and of several other HECT ligases by
binding to them.
REFERENCE 5 (bases 1 to 4666)
AUTHORS Foot,N.J., Dalton,H.E., Shearwin-Whyatt,L.M., Dorstyn,L., Tan,S.S.,
Yang,B. and Kumar,S.
TITLE Regulation of the divalent metal ion transporter DMT1 and iron
homeostasis by a ubiquitin-dependent mechanism involving Ndfips and
WWP2
JOURNAL Blood 112 (10), 4268-4275 (2008)
PUBMED 18776082
REFERENCE 6 (bases 1 to 4666)
AUTHORS Shearwin-Whyatt,L.M., Brown,D.L., Wylie,F.G., Stow,J.L. and
Kumar,S.
TITLE N4WBP5A (Ndfip2), a Nedd4-interacting protein, localizes to
multivesicular bodies and the Golgi, and has a potential role in
protein trafficking
JOURNAL J. Cell. Sci. 117 (PT 16), 3679-3689 (2004)
PUBMED 15252135
REMARK GeneRIF: N4WBP5A acts as an adaptor to recruit Nedd4 family
ubiquitin-protein ligases to the protein trafficking machinery
REFERENCE 7 (bases 1 to 4666)
AUTHORS Dunham,A., Matthews,L.H., Burton,J., Ashurst,J.L., Howe,K.L.,
Ashcroft,K.J., Beare,D.M., Burford,D.C., Hunt,S.E.,
Griffiths-Jones,S., Jones,M.C., Keenan,S.J., Oliver,K., Scott,C.E.,
Ainscough,R., Almeida,J.P., Ambrose,K.D., Andrews,D.T.,
Ashwell,R.I., Babbage,A.K., Bagguley,C.L., Bailey,J., Bannerjee,R.,
Barlow,K.F., Bates,K., Beasley,H., Bird,C.P., Bray-Allen,S.,
Brown,A.J., Brown,J.Y., Burrill,W., Carder,C., Carter,N.P.,
Chapman,J.C., Clamp,M.E., Clark,S.Y., Clarke,G., Clee,C.M.,
Clegg,S.C., Cobley,V., Collins,J.E., Corby,N., Coville,G.J.,
Deloukas,P., Dhami,P., Dunham,I., Dunn,M., Earthrowl,M.E.,
Ellington,A.G., Faulkner,L., Frankish,A.G., Frankland,J.,
French,L., Garner,P., Garnett,J., Gilbert,J.G., Gilson,C.J.,
Ghori,J., Grafham,D.V., Gribble,S.M., Griffiths,C., Hall,R.E.,
Hammond,S., Harley,J.L., Hart,E.A., Heath,P.D., Howden,P.J.,
Huckle,E.J., Hunt,P.J., Hunt,A.R., Johnson,C., Johnson,D., Kay,M.,
Kimberley,A.M., King,A., Laird,G.K., Langford,C.J., Lawlor,S.,
Leongamornlert,D.A., Lloyd,D.M., Lloyd,C., Loveland,J.E.,
Lovell,J., Martin,S., Mashreghi-Mohammadi,M., McLaren,S.J.,
McMurray,A., Milne,S., Moore,M.J., Nickerson,T., Palmer,S.A.,
Pearce,A.V., Peck,A.I., Pelan,S., Phillimore,B., Porter,K.M.,
Rice,C.M., Searle,S., Sehra,H.K., Shownkeen,R., Skuce,C.D.,
Smith,M., Steward,C.A., Sycamore,N., Tester,J., Thomas,D.W.,
Tracey,A., Tromans,A., Tubby,B., Wall,M., Wallis,J.M., West,A.P.,
Whitehead,S.L., Willey,D.L., Wilming,L., Wray,P.W., Wright,M.W.,
Young,L., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E., Beck,S.,
Bentley,D.R., Rogers,J. and Ross,M.T.
TITLE The DNA sequence and analysis of human chromosome 13
JOURNAL Nature 428 (6982), 522-528 (2004)
PUBMED 15057823
REFERENCE 8 (bases 1 to 4666)
AUTHORS Cristillo,A.D., Nie,L., Macri,M.J. and Bierer,B.E.
TITLE Cloning and characterization of N4WBP5A, an inducible,
cyclosporine-sensitive, Nedd4-binding protein in human T
lymphocytes
JOURNAL J. Biol. Chem. 278 (36), 34587-34597 (2003)
PUBMED 12796489
REMARK GeneRIF: N4WBP5A may play a regulatory role in modulating Nedd4
activity at the level of the Golgi apparatus in T lymphocytes
REFERENCE 9 (bases 1 to 4666)
AUTHORS Matsuda,A., Suzuki,Y., Honda,G., Muramatsu,S., Matsuzaki,O.,
Nagano,Y., Doi,T., Shimotohno,K., Harada,T., Nishida,E., Hayashi,H.
and Sugano,S.
TITLE Large-scale identification and characterization of human genes that
activate NF-kappaB and MAPK signaling pathways
JOURNAL Oncogene 22 (21), 3307-3318 (2003)
PUBMED 12761501
REFERENCE 10 (bases 1 to 4666)
AUTHORS Konstas,A.A., Shearwin-Whyatt,L.M., Fotia,A.B., Degger,B.,
Riccardi,D., Cook,D.I., Korbmacher,C. and Kumar,S.
TITLE Regulation of the epithelial sodium channel by N4WBP5A, a novel
Nedd4/Nedd4-2-interacting protein
JOURNAL J. Biol. Chem. 277 (33), 29406-29416 (2002)
PUBMED 12050153
REMARK GeneRIF: role in regulating epithelial sodium channel
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
DC320871.1, AB097029.1, AL136442.12 and BM976935.1.
On Jun 6, 2009 this sequence version replaced gi:55741474.
Transcript Variant: This variant (1) represents the longer
transcript and encodes the longer isoform (1).
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
##Evidence-Data-START##
Transcript exon combination :: AB032991.1, AB097019.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025082 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-73 DC320871.1 2-74
74-1900 AB097029.1 46-1872
1901-3936 AL136442.12 125243-127278 c
3937-4666 BM976935.1 1-730 c
FEATURES Location/Qualifiers
source 1..4666
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="13"
/map="13q31.1"
gene 1..4666
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/note="Nedd4 family interacting protein 2"
/db_xref="GeneID:54602"
/db_xref="HGNC:18537"
/db_xref="MIM:610041"
exon 1..401
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="alignment:Splign:1.39.8"
variation 79
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="g"
/db_xref="dbSNP:377642299"
CDS 81..1091
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/note="isoform 1 is encoded by transcript variant 1; NEDD4
WW domain-binding protein 5A; NF-kappa-B-activating
protein 413; MAPK-activating protein PM04 PM05 PM06 PM07;
NEDD4 family-interacting protein 2; putative
NF-kappa-B-activating protein 413; putative
MAPK-activating protein PM04/PM05/PM06/PM07"
/codon_start=1
/product="NEDD4 family-interacting protein 2 isoform 1"
/protein_id="NP_061953.2"
/db_xref="GI:239046738"
/db_xref="CCDS:CCDS31998.1"
/db_xref="GeneID:54602"
/db_xref="HGNC:18537"
/db_xref="MIM:610041"
/translation="
MARRRSQRVCASGPSMLNSARGAPELLRGTATNAEVSAAAAGATGSEELPPGDRGCRNGGGRGPAATTSSTGVAVGAEHGEDSLSRKPDPEPGRMDHHQPGTGRYQVLLNEEDNSESSAIEQPPTSNPAPQIVQAASSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTRYFFLL
"
misc_feature 522..533
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9NV92.2);
Region: Interaction with NEDD4 (By similarity)"
misc_feature 525..533
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9NV92.2);
Region: PY 1"
misc_feature 531..533
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphotyrosine, by SRC, dependent on Y-167;
propagated from UniProtKB/Swiss-Prot (Q9NV92.2);
phosphorylation site"
misc_feature 579..581
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphotyrosine, by SRC; propagated from
UniProtKB/Swiss-Prot (Q9NV92.2); phosphorylation site"
misc_feature 591..593
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphotyrosine, by SRC, dependent on Y-167;
propagated from UniProtKB/Swiss-Prot (Q9NV92.2);
phosphorylation site"
misc_feature <594..1073
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/note="Protein of unknown function (DUF2370); Region:
DUF2370; pfam10176"
/db_xref="CDD:192470"
misc_feature 603..611
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9NV92.2);
Region: PY 2"
misc_feature 609..611
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphotyrosine, by SRC, dependent on Y-167;
propagated from UniProtKB/Swiss-Prot (Q9NV92.2);
phosphorylation site"
misc_feature 630..638
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9NV92.2);
Region: PY 3"
misc_feature 636..638
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/experiment="experimental evidence, no additional details
recorded"
/note="Not phosphorylated by SRC; propagated from
UniProtKB/Swiss-Prot (Q9NV92.2); other site"
misc_feature 774..836
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9NV92.2);
transmembrane region"
misc_feature 852..914
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9NV92.2);
transmembrane region"
misc_feature 942..1004
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9NV92.2);
transmembrane region"
variation 97
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:143536057"
variation 153
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:3814278"
variation 179
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="g"
/db_xref="dbSNP:183195124"
variation 196
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:113662422"
variation 249
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="t"
/db_xref="dbSNP:201081260"
variation 283
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="c"
/db_xref="dbSNP:375938709"
variation 292
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="c"
/db_xref="dbSNP:371311268"
variation 294
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:370820502"
variation 342
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:368971046"
exon 402..567
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="alignment:Splign:1.39.8"
variation 416
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:149865944"
variation 442
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:144950614"
variation 450
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:55887763"
variation 468
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:373903171"
variation 469
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:146047464"
variation 470
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:368345034"
variation 487
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:11549502"
variation 488
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:371388745"
variation 535
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:61735407"
variation 540
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:371917287"
variation 561
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:371287967"
exon 568..701
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="alignment:Splign:1.39.8"
variation 580
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:143612506"
variation 581
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:117933987"
variation 582
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:141843405"
variation 592
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:368610434"
variation 596
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:150182671"
variation 611
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:138905931"
variation 615
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:142039160"
variation 648
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="g"
/db_xref="dbSNP:371885469"
variation 669
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:375021774"
variation 677
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="t"
/db_xref="dbSNP:146142126"
exon 702..795
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="alignment:Splign:1.39.8"
variation 716
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="g"
/replace="t"
/db_xref="dbSNP:139711651"
exon 796..920
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="alignment:Splign:1.39.8"
variation 811
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:149607151"
variation 845
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:144392564"
variation 902
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:374117696"
exon 921..987
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="alignment:Splign:1.39.8"
variation 938
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:148785504"
variation 939
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:373812761"
exon 988..1093
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="alignment:Splign:1.39.8"
exon 1094..4655
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="alignment:Splign:1.39.8"
variation 1125
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="g"
/db_xref="dbSNP:193206553"
variation 1128
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:183469703"
variation 1211
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:1212082"
STS 1220..1469
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/standard_name="STS-AA037467"
/db_xref="UniSTS:6301"
variation 1223
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="g"
/replace="t"
/db_xref="dbSNP:17071601"
variation 1251
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:59945183"
variation 1462
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:368513684"
variation 1603
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:41288270"
variation 1618
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:74922628"
STS 1670..1865
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/standard_name="WI-22692"
/db_xref="UniSTS:2937"
variation 1678
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:150468706"
variation 1695
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="c"
/db_xref="dbSNP:116166707"
STS 1712..1929
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/standard_name="RH44816"
/db_xref="UniSTS:90128"
variation 1785..1786
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace=""
/replace="ac"
/db_xref="dbSNP:34603928"
variation 1786..1787
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace=""
/replace="ac"
/db_xref="dbSNP:72108250"
variation 1814
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:12585004"
variation 1822..1823
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace=""
/replace="aa"
/db_xref="dbSNP:34511187"
variation 1901
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:700396"
variation 1917
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:8000301"
STS 1928..2087
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/standard_name="RH45196"
/db_xref="UniSTS:80258"
variation 1979
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="g"
/replace="t"
/db_xref="dbSNP:370849898"
variation 2078
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:7981574"
variation 2164
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:187357067"
variation 2192
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:74100740"
STS 2263..2406
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/standard_name="RH78426"
/db_xref="UniSTS:9203"
variation 2281
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="g"
/replace="t"
/db_xref="dbSNP:41288272"
variation 2513
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="g"
/replace="t"
/db_xref="dbSNP:191800517"
variation 2569
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:183923591"
variation 2602
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace=""
/replace="a"
/db_xref="dbSNP:375300709"
variation 2760
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:188416304"
variation 2778
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:149221742"
variation 2987
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:1044647"
variation 3003..3004
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace=""
/replace="g"
/db_xref="dbSNP:34370878"
variation 3025
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:192415007"
variation 3072
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:9924"
STS 3115..3299
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/standard_name="RH93391"
/db_xref="UniSTS:87224"
variation 3127
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:7988143"
variation 3233
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:368435397"
variation 3435
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="t"
/db_xref="dbSNP:146884822"
variation 3447
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:139061774"
variation 3484
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="g"
/db_xref="dbSNP:143034581"
variation 3551
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:147451134"
variation 3682
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="g"
/db_xref="dbSNP:148125298"
variation 3765
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="c"
/db_xref="dbSNP:372106051"
variation 3771
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:2760102"
variation 3917
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:184269526"
variation 4054
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:116562947"
variation 4149
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:141886349"
variation 4193
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:115975942"
variation 4265
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:190434266"
variation 4502
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:368029245"
ORIGIN
acaacctagacagctcccccggacttgccttacttttccatctcctcccacccagctataccctcccactggcggcgcggatggcacgccggcggagccagcgagtctgcgcgagcggtccgagcatgctcaatagcgcgcgcggcgccccggagcttctccgcggaaccgcgaccaacgcggaggtctcggcggccgctgcgggagccacaggaagtgaagagcttccgccgggagaccgcggctgcaggaacggaggcggaaggggccctgcggcgacgacgtcgtcgacgggggtggccgtgggagctgagcacggagaagactccctctctcggaagccggatcccgagccgggcaggatggatcaccaccagccggggactgggcgctaccaggtgcttcttaatgaagaggataactcagaatcatcggctatagagcagccacctacttcaaacccagcaccgcagattgtgcaggctgcgtcttcagcaccagcacttgaaactgactcttcccctccaccatatagtagtattactgtggaagtacctacaacttcagatacagaagtttacggtgagttttatcccgtgccacctccctatagcgttgctacctctcttcctacatacgatgaagctgagaaggctaaagctgctgcaatggcagctgcagcagcagaaacatctcaaagaattcaggaggaagagtgtccaccaagagatgacttcagtgatgcagaccagctcagagtggggaatgatggcattttcatgctggcatttttcatggcatttattttcaactggcttggattttgtttatccttctgtatcaccaataccatagctggaaggtatggtgctatctgcggatttggcctttccttgatcaaatggatccttattgtcaggttttctgattattttactggatatttcaatggacagtattggctttggtggatatttcttgtacttggcctgctccttttcttcagaggatttgttaattatctaaaagtcagaaacatgtctgaaagtatggcagctgctcatagaacaaggtatttcttcttattgtagagactgcatcaacccgacattcctttcttataccaatgtgaaatttccagatcatctgtaaacctacaactttaatagaagactactaataacagaagacaaattagtgaagaaaagacggagtttcgaaattgaatggcagggtggtttttgcttacaagccatttctgttcattctttaagtatctatatttcatttgttttgcacatatgcatatgtgcccatttaagatatttgcatatacttgatagaaaccataaagttgtagcagttaagtccagtcacatttggttaatcagtgtttgatataattgaaagagttgagtggataaacagtcttccagcttgtaaatgccattgacttctgacctgacatttagtataataaaaatgaaattcttaaccatgtcaaatgatttagtttctggctcttagactcatctggcagttctacacatgaaacatcttttgttatataaggtgtattgaaacctgcagtgctgattattagaaaggatttgtcagatttttgaacatgatatttacattattatttaggaaaactcttcctgtaaataaccatgcataacttactttctgcaatgttttcttagaaattgtgtccagatagctttcactaattttaaattaagtgaactaaatatatatgtgtatatgtatacacatatatatacacacacacatatatatatttagaaacgtgagtgttaaagatagaatttgttttaggacaaattttaagaaaatgtgggaataccaaatgtcctttataagaaaaataaattttattttaagggacatactagttttagggattttcagatgggaagctgcatttttaggattgcccatcttaagagatcttgcaggaagagattgtattagatattatatttatttcatttaagataattttcaaagttaattttctaaataagataattctcatttgtgtttgtcttttaaaaggccaataaaatatctttcagtatcattgtaataattttttagagtttaatttgtaaagcttagcaaataaaatcttgtactatgaatagcttcttgctttatgactttaggattaacttgtaaaaaacatatcctgaactgagatatgcaaaatactcattttcaagttatggaaatgtgtttgtggcatataggactgtggggtctgtgtgtgtagtgagagtgtgtagccactattataactggaatttaatttacattcataaactactatatttcccatcttgcaaatcattttatgtctcatctgtttttcctttcggttatatctttggttttgaataccaacatttaaaatgatggtattttatcttttaaacttaaaaattatttaatacagctatatggaccttataaaattgatttcttatttattattagacattactactaaaaggtacatctaactattcagggacatttttccatttccaaaaaataaaatttattatgctttataacctcttctgtattttctaattttttcattgtctttgataaataaaacagttttgttttgctaatatagcctattttttgttttgtctcattcagtttactttcctgcgtagaatttttattgttatattaaaatttttattgttgtattaaagtacctgtgttacaccccttgaagtaagacagtagcatggggtaaagaaaaaatatttagtttagttgcctaatttggaagttaattaaaattaaactgtactaataacatattcaaactcatgctggatctctttcatattaatttcttatagacctgtactttattctttcaataatttttaaatgaaattaagctttgctacatggtaattaaataattactaggaagcttagctatcaaacatcgacttactaaaatttcattttagcttttatggtatatgtgcttgttttctgaatatggatacatgttacttttgatccagcatcaaaacttcactttttgttttgacttttccccccaaatctgtaaggttcaagtatacatattactgaatcctctataattggcataattcaatggtagccttaaatctcatcatgtaagcaggggaatcagaatgttattttcaagaacttaatgttcccttcagatatataaaatcctgcatacttcatttcctgtgagcttgaacagctgctgttgtgttttggggatgcttgatcatctttgcactctgccttaaagattgaaaaatcaaaactcttgttagggtatctaaacatttttgagtgtgaactggggattggaagttaatacaaaaaaatttcaaattatttctattgtaaatgaataagctagtcatggctaggataatccattttcatgtatttatgcaataaactgaattttaaggcaaaaacaacacttttctatatagtgtatgcaggacagattttagaaacttagattaaaatacaaatcccattacatttggttaaaatgaaaatctctgcttaatggaaaaaatactaatctttagcctattttgagtctataagatatatttcattttagacatgccttctaagttgttcacagatttttacctgctaaaacaatattatttccagtaaaacctctcctaacaggaaaagtggagttcaaaatatccaattggagaaaaattcagagttccttcattaaatataatttttttcatctagtatgtactatttcaagaagtgcaaaaagtaatgatagtgaatgtgataccatacttaactaaggtaatatatatccttagtttgctcaaaagagtcctggttattcctgttttctcagcttaatagtgcctcatcgtactctcaaaagtgttctaatttggaggataagttatatgatcatcctgtgtataattgtagactgtaccaagaagcaactaccttagctccactgccctttgagggatggaactggggtaagggcaggagccagttattattgccacagtgttttctaatgaaccatttggcctgtagaagaggaatagtattttttttaatagttgtatttgaatgattccagcttatcgtaaatactaaactgaatggcttttatatttttaactgctgttaaatgttattttagcatttattagttgtttattatttaattcttcaaatagtcatatgaaaacatatatttgataaaggtcaattgttagatgataatgtgccattcattatcataggaatgtccttgcccatatataaaacatgctggcatgtattttacttgttaataaagttgtatagatgtggaagtgtgaacctgtgatgcatccttttcaaaatcagtttaagattcgcatattatcatgactgtgacctcactaaactgtttatgtgacaaacctttcaagattggagatgaaaacaacacttgtgaaattaggttggggttgcaacatcttttaacttctcagttatttgtatgtcaggagacagattgtggtttaattttaataaacaaaatatcatctttttgaaaataaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:54602 -> Molecular function: GO:0004871 [signal transducer activity] evidence: IMP
GeneID:54602 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:54602 -> Molecular function: GO:0050699 [WW domain binding] evidence: IPI
GeneID:54602 -> Biological process: GO:0007165 [signal transduction] evidence: IMP
GeneID:54602 -> Biological process: GO:0010629 [negative regulation of gene expression] evidence: IMP
GeneID:54602 -> Biological process: GO:0031398 [positive regulation of protein ubiquitination] evidence: IMP
GeneID:54602 -> Biological process: GO:0032410 [negative regulation of transporter activity] evidence: IMP
GeneID:54602 -> Biological process: GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB cascade] evidence: IMP
GeneID:54602 -> Biological process: GO:0051224 [negative regulation of protein transport] evidence: IMP
GeneID:54602 -> Cellular component: GO:0000139 [Golgi membrane] evidence: IEA
GeneID:54602 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:54602 -> Cellular component: GO:0005739 [mitochondrion] evidence: IDA
GeneID:54602 -> Cellular component: GO:0005783 [endoplasmic reticulum] evidence: IDA
GeneID:54602 -> Cellular component: GO:0005794 [Golgi apparatus] evidence: IDA
GeneID:54602 -> Cellular component: GO:0016021 [integral to membrane] evidence: IEA
GeneID:54602 -> Cellular component: GO:0032585 [multivesicular body membrane] evidence: IEA
GeneID:54602 -> Cellular component: GO:0048471 [perinuclear region of cytoplasm] evidence: IDA
by
@meso_cacase at
DBCLS
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