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2024-04-16 21:16:23, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_018204 3733 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens cytoskeleton associated protein 2 (CKAP2), transcript
variant 1, mRNA.
ACCESSION NM_018204
VERSION NM_018204.3 GI:148664243
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3733)
AUTHORS Kang,D.S., Hong,K.M., Park,J. and Bae,C.D.
TITLE Cyclin A regulates a cell-cycle-dependent expression of CKAP2
through phosphorylation of Sp1
JOURNAL Biochem. Biophys. Res. Commun. 420 (4), 822-827 (2012)
PUBMED 22465120
REMARK GeneRIF: GC box was responsible for the cyclic activity of human
CKAP2 promoter through the phosphorylation of Sp1, possibly by
Cyclin A/Cdk complex.
REFERENCE 2 (bases 1 to 3733)
AUTHORS Kim,H.J., Kwon,H.R., Bae,C.D., Park,J. and Hong,K.U.
TITLE Specific primary sequence requirements for Aurora B kinase-mediated
phosphorylation and subcellular localization of TMAP during mitosis
JOURNAL Cell Cycle 9 (10), 2027-2036 (2010)
PUBMED 20458174
REMARK GeneRIF: Findings suggest that the motif surrounding Ser627 ((625)
RRSRRL (630)) is a critical for kinase-substrate recognition and
for regulation of the subcellular localization of TMAP during
mitosis.
REFERENCE 3 (bases 1 to 3733)
AUTHORS Hong,K.U., Kim,H.J., Bae,C.D. and Park,J.
TITLE Characterization of mitosis-specific phosphorylation of
tumor-associated microtubule-associated protein
JOURNAL Exp. Mol. Med. 41 (11), 832-840 (2009)
PUBMED 19641375
REMARK GeneRIF: TMAP is limited to pre-anaphase stages and suggest that
the multiple phosphorylation may not act in concert but serve
diverse functions.
REFERENCE 4 (bases 1 to 3733)
AUTHORS Hong,K.U., Kim,H.J., Kim,H.S., Seong,Y.S., Hong,K.M., Bae,C.D. and
Park,J.
TITLE Cdk1-cyclin B1-mediated phosphorylation of tumor-associated
microtubule-associated protein/cytoskeleton-associated protein 2 in
mitosis
JOURNAL J. Biol. Chem. 284 (24), 16501-16512 (2009)
PUBMED 19369249
REMARK GeneRIF: Cdk1-cyclin B1-mediated phosphorylation of TMAP is
important for and contributes to proper regulation of microtubule
dynamics and establishment of functional bipolar spindles during
mitosis
REFERENCE 5 (bases 1 to 3733)
AUTHORS Seki,A. and Fang,G.
TITLE CKAP2 is a spindle-associated protein degraded by APC/C-Cdh1 during
mitotic exit
JOURNAL J. Biol. Chem. 282 (20), 15103-15113 (2007)
PUBMED 17376772
REMARK GeneRIF: CKAP2 is a physiological substrate of anaphase-promoting
complex/cyclosome during mitotic exit and that a tight regulation
of the CKAP2 protein level is critical for the normal mitotic
progression.
REFERENCE 6 (bases 1 to 3733)
AUTHORS Bae,C.D., Sung,Y.S., Jeon,S.M., Suh,Y., Yang,H.K., Kim,Y.I.,
Park,K.H., Choi,J., Ahn,G. and Park,J.
TITLE Up-regulation of cytoskeletal-associated protein 2 in primary human
gastric adenocarcinomas
JOURNAL J. Cancer Res. Clin. Oncol. 129 (11), 621-630 (2003)
PUBMED 12942315
REFERENCE 7 (bases 1 to 3733)
AUTHORS Rakhmanaliev,E.R., Klimov,E.A., Kompaniitsev,A.A. and Sulimova,G.E.
TITLE [The structure of the human oncogenesis-associated CKAP2 (LB1)
gene]
JOURNAL Mol. Biol. (Mosk.) 36 (6), 985-989 (2002)
PUBMED 12500535
REMARK GeneRIF: CKAP2 comprises nine exons ranging 70-1442 bp and is about
22 kb in size (regulatory regions included). The CKAP2 promoter
contains CCAAT (-39...-33) rather than the canonical TATA box, and
harbors nine binding sites for six transcription factors
REFERENCE 8 (bases 1 to 3733)
AUTHORS Eichmuller,S., Usener,D., Dummer,R., Stein,A., Thiel,D. and
Schadendorf,D.
TITLE Serological detection of cutaneous T-cell lymphoma-associated
antigens
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 98 (2), 629-634 (2001)
PUBMED 11149944
REFERENCE 9 (bases 1 to 3733)
AUTHORS Udina,I.G., Baranova,A.V., Kompaniitsev,A.A. and Sulimova,G.E.
TITLE [Evolutionarily-conserved gene CKAP2,located in region 13q14.3 of
the human genome, is frequently rearranged in various tumors]
JOURNAL Genetika 37 (1), 120-123 (2001)
PUBMED 11234418
REFERENCE 10 (bases 1 to 3733)
AUTHORS Maouche-Chretien,L., Deleu,N., Badoual,C., Fraissignes,P.,
Berger,R., Gaulard,P., Romeo,P.H. and Leroy-Viard,K.
TITLE Identification of a novel cDNA, encoding a cytoskeletal associated
protein, differentially expressed in diffuse large B cell lymphomas
JOURNAL Oncogene 17 (10), 1245-1251 (1998)
PUBMED 9771967
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
BM541375.1, AK022982.1, AY062261.1, AK027103.1 and DB512858.1.
On Jun 7, 2007 this sequence version replaced gi:19923520.
Summary: CKAP2 is a cytoskeleton-associated protein involved in
mitotic progression (Seki and Fang, 2007 [PubMed
17376772]).[supplied by OMIM, Mar 2008].
Transcript Variant: This variant uses an alternate splice acceptor
site at the beginning of the third coding exon.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AK022982.1, AY062261.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025082 [ECO:0000348]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-101 BM541375.1 6-106
102-1018 AK022982.1 1-917
1019-3454 AY062261.1 940-3375
3455-3466 AK022982.1 3354-3365
3467-3728 AK027103.1 1514-1775
3729-3733 DB512858.1 252-256
FEATURES Location/Qualifiers
source 1..3733
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="13"
/map="13q14"
gene 1..3733
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/note="cytoskeleton associated protein 2"
/db_xref="GeneID:26586"
/db_xref="HGNC:1990"
/db_xref="MIM:611569"
exon 1..267
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/inference="alignment:Splign:1.39.8"
variation 4
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:187957314"
variation 16
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="g"
/replace="t"
/db_xref="dbSNP:4995048"
variation 98
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:114633402"
variation 100
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:369884298"
variation 111
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:192149786"
variation 120
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:369671577"
misc_feature 141..143
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/note="upstream in-frame stop codon"
variation 157
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:370818383"
variation 173
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:375041874"
variation 179
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:368345050"
variation 184
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:372978529"
CDS 198..2246
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/note="isoform 1 is encoded by transcript variant 1;
cytoskeleton-associated protein 2; tumor-associated
microtubule-associated protein; CTCL tumor antigen
se20-10; tumor- and microtubule-associated protein"
/codon_start=1
/product="cytoskeleton-associated protein 2 isoform 1"
/protein_id="NP_060674.3"
/db_xref="GI:148664244"
/db_xref="CCDS:CCDS9435.1"
/db_xref="GeneID:26586"
/db_xref="HGNC:1990"
/db_xref="MIM:611569"
/translation="
MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENIIAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGVDVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYLQSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGRETDAFVCRPNAALCRVYYEADTT
"
misc_feature 1794..1796
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q8WWK9.1); phosphorylation site"
misc_feature 1929..1931
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (Q8WWK9.1); phosphorylation site"
misc_feature 1938..1940
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (Q8WWK9.1); phosphorylation site"
misc_feature 1977..1979
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q8WWK9.1); phosphorylation site"
misc_feature 1980..1982
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (Q8WWK9.1); phosphorylation site"
misc_feature 1983..1985
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (Q8WWK9.1); phosphorylation site"
misc_feature 1989..1991
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphotyrosine; propagated from
UniProtKB/Swiss-Prot (Q8WWK9.1); phosphorylation site"
misc_feature 1998..2000
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q8WWK9.1); phosphorylation site"
variation 216
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:146292755"
exon 268..352
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/inference="alignment:Splign:1.39.8"
variation 282
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:139637131"
variation 293
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:149997663"
variation 316
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:202147843"
variation 325
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:145357920"
exon 353..428
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/inference="alignment:Splign:1.39.8"
exon 429..1297
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/inference="alignment:Splign:1.39.8"
variation 435
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:373545539"
variation 464
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:376367571"
variation 491
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:149189169"
variation 526
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:36022164"
variation 576
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:138583090"
variation 621
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:201217629"
variation 622
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:370214081"
variation 635
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:372390966"
variation 708
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:376545198"
variation 714
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:149254206"
variation 733
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:184495852"
variation 735
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="g"
/db_xref="dbSNP:370906992"
variation 759
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:202229967"
variation 779
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:147763631"
variation 854
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:111764793"
variation 870
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="g"
/replace="t"
/db_xref="dbSNP:368615547"
variation 876
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="g"
/db_xref="dbSNP:370863834"
variation 884
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:376206456"
variation 901
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="t"
/db_xref="dbSNP:35975899"
variation 912
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:368402985"
variation 943
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:371667488"
variation 945
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:150312116"
variation 946
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:138054585"
variation 975
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:144431404"
variation 976
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:375956975"
variation 997
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:367704222"
variation 1011
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:143204885"
variation 1015
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="g"
/replace="t"
/db_xref="dbSNP:138768856"
variation 1019
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:7337054"
variation 1026
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:146302747"
variation 1035
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:368666806"
variation 1038
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:200602489"
variation 1051
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:200233086"
variation 1133
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="t"
/db_xref="dbSNP:74085795"
variation 1135
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:141913418"
variation 1161
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:7335867"
variation 1178
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:369584518"
variation 1184
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="t"
/db_xref="dbSNP:373047177"
variation 1196
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:3809374"
variation 1252
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:201553403"
variation 1280
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:375430927"
variation 1285
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:141769986"
exon 1298..1502
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/inference="alignment:Splign:1.39.8"
variation 1319
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:139910485"
variation 1325
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="g"
/db_xref="dbSNP:369722906"
variation 1332
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:373418118"
variation 1336
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:200225546"
variation 1353
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:74085799"
variation 1355
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="g"
/replace="t"
/db_xref="dbSNP:200669300"
variation 1358
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:140212356"
variation 1393
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:200158115"
variation 1396
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:370145315"
variation 1405
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="g"
/replace="t"
/db_xref="dbSNP:201326864"
variation 1468
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:373389022"
exon 1503..1673
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/inference="alignment:Splign:1.39.8"
variation 1507
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:145609331"
variation 1510
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:147773280"
variation 1515
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:148820633"
variation 1524
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="g"
/db_xref="dbSNP:192868791"
variation 1525
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:377639183"
variation 1547
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="t"
/db_xref="dbSNP:371432306"
variation 1558
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:147937279"
variation 1603
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:201479437"
variation 1620
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:143514154"
exon 1674..1743
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/inference="alignment:Splign:1.39.8"
variation 1689
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:150954069"
variation 1692
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:140760250"
variation 1701
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:117024941"
variation 1712
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:138633500"
variation 1718..1719
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace=""
/replace="c"
/db_xref="dbSNP:34902853"
variation 1723
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="g"
/db_xref="dbSNP:375816758"
exon 1744..1999
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/inference="alignment:Splign:1.39.8"
variation 1746
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:41292820"
variation 1748
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:112465889"
variation 1752
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:200189892"
variation 1774
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:377566863"
variation 1807
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="g"
/db_xref="dbSNP:369352268"
variation 1864
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="g"
/replace="t"
/db_xref="dbSNP:145551694"
variation 1897
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:373740676"
variation 1915
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:201305173"
variation 1946
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:377669665"
variation 1961
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:368021748"
variation 1984
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:138265024"
exon 2000..3733
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/inference="alignment:Splign:1.39.8"
variation 2034
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="g"
/replace="t"
/db_xref="dbSNP:200166848"
variation 2048
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:41292822"
variation 2052
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:376894890"
variation 2066
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:149052925"
variation 2080
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:370416292"
variation 2083
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:73186408"
variation 2086
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:373578702"
variation 2168
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="g"
/db_xref="dbSNP:34624748"
variation 2171
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:147510699"
variation 2196
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:140040526"
variation 2217
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:202031498"
variation 2237
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:34494025"
variation 2270
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:201310249"
variation 2271
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:201018318"
variation 2275
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:199938465"
variation 2323..2324
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace=""
/replace="g"
/db_xref="dbSNP:35893582"
STS 2353..2656
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/standard_name="RH106549"
/db_xref="UniSTS:209623"
variation 2395
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:141447887"
variation 2456
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:115036651"
variation 2462
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:74850630"
variation 2664
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="c"
/db_xref="dbSNP:192600543"
variation 2712
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="g"
/db_xref="dbSNP:78029237"
variation 2846
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:374584816"
variation 2959
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:184535702"
variation 2989
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:116458749"
variation 3221
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:78524889"
variation 3292
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:189212554"
variation 3385
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="g"
/replace="t"
/db_xref="dbSNP:202188690"
variation 3449
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:9379"
variation 3593
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="a"
/replace="g"
/db_xref="dbSNP:41292824"
variation 3607
/gene="CKAP2"
/gene_synonym="LB1; se20-10; TMAP"
/replace="c"
/replace="t"
/db_xref="dbSNP:181058098"
ORIGIN
accggccccggcaactgcagtccaggctccgcctccctacgcccattggcttattcaattcacgcaggaaccaatgggcggagacggcagccgcgccgtctgacggcttagccgcggtgcagactgcggcggcggtggtctgaggaagttctatcttggcgctaaagcggagacgcatcccccgacccgaggctacgatgagcacaccggccgtgccccaggacctgcagctgcccccgagtcagagggcgcagtccgcattcaaagagcaaagaagacaaaaactcaaggaacatctgttgagaagaaaaacgctttttgcatacaagcaggaaaatgagatgttatccagtagagatcagagagttgtgacatctgaggaccaagttcaagaagggactaaagtgctgaaacttaaaacaaaaatggctgataaagaaaacatgaagagacctgcagagagcaaaaataatacagtggtggggaaacattgtattcctttaaaaccttcaaatgaactaaccaattcaactgtagtaattgacacacataaacctaaggatagtaatcaaactccgcatttgttactaactgaagatgatccccaaagtcaacatatgacattaagccaggcatttcaccttaaaaacaatagtaaaaagaaacaaatgactacagaaaaacaaaagcaagatgctaacatgcccaagaaacctgtgcttggatcttatcgtggccagattgttcagtctaagattaattcatttagaaaacctctacaagtcaaagatgagagttctgcagcaacaaagaaactttcagccactatacctaaagccacaaaacctcagcctgtaaacaccagcagtgtaacagtgaaaagtaatagatcctccaatatgactgccactactaaatttgtgagcactacatctcagaacacacaacttgtgcgacctcctattagaagtcatcacagtaatacccgggacactgtgaaacaaggcatcagtagaacttctgccaatgttacaatccggaaagggcctcatgaaaaagaactattacaatcaaaaacagctttatctagtgtcaaaaccagttcttctcaaggtataataagaaataagactctatcaagatccatagcatctgaagttatagccaggcctgcttcattgtctaatgataaactgatggaaaagtcagagcccgttgaccagcgaagacatactgcaggaaaagcaattgttgatagtagatcagctcagcccaaagaaacctcggaagagagaaaagctcgtctgagtgagtggaaagctggcaaaggaagagtgctaaaaaggccccctaattcagtagttactcagcatgagcctgcaggacaaaatgaaaaaccagttgggtctttttggactaccatggcagaagaagatgaacaaagattatttactgaaaaagtaaacaacacattttctgaatgcctgaacttgattaatgagggatgtccaaaagaagatatactggtcacactgaatgacctgattaaaaatattccagatgccaaaaagcttgttaagtattggatatgtcttgcacttattgaaccaatcacaagtcctattgaaaatattattgcaatctatgagaaagccattctggcaggggctcagcctattgaagagatgcgacacacgattgtagatattctaacaatgaagagtcaagaaaaagctaatttaggagaaaatatggagaagtcttgtgcaagcaaggaagaagtcaaagaagtcagtattgaagatacaggtgttgatgtagatccagaaaaactggaaatggagagtaaacttcatagaaatttgctatttcaagattgtgaaaaagagcaagacaacaaaacaaaagatccaacccatgatgttaaaacccccaatacagaaacgaggacaagttgcttaattaaatataatgtgtctactacgccatacttgcaaagtgtgaaaaaaaaggtgcagtttgatggaacaaattccgcatttaaagagctgaagtttttaacaccagtgagacgttctcgacgtcttcaagagaaaacttctaaattgccagatatgttaaaagatcattatccttgtgtgtcttcattggaacagctaacggagttgggaagagaaactgatgcttttgtatgccgccctaatgcagcactgtgccgggtgtactatgaggctgatacaacataagagaaataaagctctgttagggaatggggtttttattatttgtggggtgttttgttttgagtagctttatattgctcttaggtctggagttggccatgtacctatgtatcctaagcattcacggcagtgagctcctttactaacattcatgttatggcaagagttgtcctctacattggaaagctaatcctaccttgtcagtttcaaccaactgagttttttctttaagaaaggtaaattttgtcagctagtttactatgttccttgaatataaacaggttataatactaccctgttcactttactaaatataagtacagtaatgatgcataattagaaaatgaggtattctaggtaaaatgtatgtttgccttgacatgtttttaaaagttatgatgtacctccctgcctttaaacagaatacttttttcttttttttggcctttctcagattagtcaaaaattctatagaatgactcacttcgaatactaagacacaggaggtttagcctgctttcttaccaaattcatgttacccagacttgtgttctcttgcgtcccttggactgcctgttgattgatggaaagtgtctgcactgacacttttcgtcagtagtctgtagtttcgtggcctcttttgattataactggggtcaccaagaaggtttacttaattaaataccgcatttctaagagaagatactttgtgtaagaaaagatgccacatttagtggtttaacttttgtaacttcacttgatagtttttaagcaattagaatggagttagggaaagaacatatcatactgaacaaatgtcattctagtttagatagcatttctaagataactgatactaatacttgttttcttccctataacataaaaaacttcactgttaagtcatgtcccttgaaacatgatagttacatacacagttttctctccacacataaataacaccactaaagttgttttgtaaggttccaaactaatatggcatatatcaactctacagtttcaaataaatgactttttaattgtaaaagattagttgaaaaactgtatgaatgtgaagatcacatgcttagtcatttttatgttcattccactttgtatatcttttctatttattgacttctcatgttctagagagtaggacttttattccgtgtacctgatatatatacaattaaaatatctgtgtaattatgttttaatgaagtttatttcaacagatattttatgaaatgcagtttaaccacagtgaatgaattttagctttgcttttgaaatacattgtaagatttgacttgaggtttttgacacttaagtacatgcttaatgatatattttcaaaagtcatcagtctacttacataaactttacctaatttttttcactttaacaaaaacataactatgcccttgttttttcatactttgacccaaaatatgccattttgaaataaaatttaagctttgatacac
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:26586 -> Biological process: GO:0000281 [mitotic cytokinesis] evidence: IGI
GeneID:26586 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:26586 -> Biological process: GO:0007026 [negative regulation of microtubule depolymerization] evidence: IEA
GeneID:26586 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IGI
GeneID:26586 -> Cellular component: GO:0000922 [spindle pole] evidence: IEA
GeneID:26586 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:26586 -> Cellular component: GO:0005813 [centrosome] evidence: IDA
GeneID:26586 -> Cellular component: GO:0005881 [cytoplasmic microtubule] evidence: IDA
GeneID:26586 -> Cellular component: GO:0015630 [microtubule cytoskeleton] evidence: IDA
by
@meso_cacase at
DBCLS
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