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2019-03-23 03:41:26, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_018003               6873 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens uveal autoantigen with coiled-coil domains and ankyrin
            repeats (UACA), transcript variant 1, mRNA.
ACCESSION   NM_018003
VERSION     NM_018003.2  GI:59850761
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6873)
  AUTHORS   Moravcikova,E., Krepela,E., Prochazka,J., Rousalova,I., Cermak,J.
            and Benkova,K.
  TITLE     Down-regulated expression of apoptosis-associated genes APIP and
            UACA in non-small cell lung carcinoma
  JOURNAL   Int. J. Oncol. 40 (6), 2111-2121 (2012)
   PUBMED   22407486
  REMARK    GeneRIF: The down-regulation of APIP and UACA expression suggests
            that the threshold to activate the apoptosome apparatus may be
            decreased in non-small cell lung cancer cells.
REFERENCE   2  (bases 1 to 6873)
  AUTHORS   Trynka,G., Zhernakova,A., Romanos,J., Franke,L., Hunt,K.A.,
            Turner,G., Bruinenberg,M., Heap,G.A., Platteel,M., Ryan,A.W., de
            Kovel,C., Holmes,G.K., Howdle,P.D., Walters,J.R., Sanders,D.S.,
            Mulder,C.J., Mearin,M.L., Verbeek,W.H., Trimble,V., Stevens,F.M.,
            Kelleher,D., Barisani,D., Bardella,M.T., McManus,R., van Heel,D.A.
            and Wijmenga,C.
  TITLE     Coeliac disease-associated risk variants in TNFAIP3 and REL
            implicate altered NF-kappaB signalling
  JOURNAL   Gut 58 (8), 1078-1083 (2009)
   PUBMED   19240061
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   3  (bases 1 to 6873)
  AUTHORS   Cockman,M.E., Lancaster,D.E., Stolze,I.P., Hewitson,K.S.,
            McDonough,M.A., Coleman,M.L., Coles,C.H., Yu,X., Hay,R.T.,
            Ley,S.C., Pugh,C.W., Oldham,N.J., Masson,N., Schofield,C.J. and
            Ratcliffe,P.J.
  TITLE     Posttranslational hydroxylation of ankyrin repeats in IkappaB
            proteins by the hypoxia-inducible factor (HIF) asparaginyl
            hydroxylase, factor inhibiting HIF (FIH)
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 103 (40), 14767-14772 (2006)
   PUBMED   17003112
REFERENCE   4  (bases 1 to 6873)
  AUTHORS   Ohkura,T., Taniguchi,S., Yamada,K., Nishio,N., Okamura,T.,
            Yoshida,A., Kamijou,K., Fukata,S., Kuma,K., Inoue,Y., Hisatome,I.,
            Senju,S., Nishimura,Y. and Shigemasa,C.
  TITLE     Detection of the novel autoantibody (anti-UACA antibody) in
            patients with Graves' disease
  JOURNAL   Biochem. Biophys. Res. Commun. 321 (2), 432-440 (2004)
   PUBMED   15358194
  REMARK    GeneRIF: UACA is a novel candidate for eye muscle autoantigens in
            thyroid-associated ophthalmopathy
REFERENCE   5  (bases 1 to 6873)
  AUTHORS   Beausoleil,S.A., Jedrychowski,M., Schwartz,D., Elias,J.E.,
            Villen,J., Li,J., Cohn,M.A., Cantley,L.C. and Gygi,S.P.
  TITLE     Large-scale characterization of HeLa cell nuclear phosphoproteins
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004)
   PUBMED   15302935
REFERENCE   6  (bases 1 to 6873)
  AUTHORS   Yamada,K., Senju,S., Nakatsura,T., Murata,Y., Ishihara,M.,
            Nakamura,S., Ohno,S., Negi,A. and Nishimura,Y.
  TITLE     Identification of a novel autoantigen UACA in patients with
            panuveitis
  JOURNAL   Biochem. Biophys. Res. Commun. 280 (4), 1169-1176 (2001)
   PUBMED   11162650
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CN303461.1, AF322916.1, AB046781.2, BM693348.1, AC087699.11 and
            BU736944.1.
            On Feb 15, 2005 this sequence version replaced gi:24308154.
            
            Transcript Variant: This variant (1) represents the shorter
            transcript but encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB046781.2, BC113409.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           ERS025081, ERS025082 [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-55                CN303461.1         2-56
            56-520              AF322916.1         1-465
            521-3058            AB046781.2         417-2954
            3059-3334           BM693348.1         212-487
            3335-4477           AB046781.2         3231-4373
            4478-6294           AC087699.11        115182-116998       c
            6295-6873           BU736944.1         1-579               c
FEATURES             Location/Qualifiers
     source          1..6873
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q22-q24"
     gene            1..6873
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /note="uveal autoantigen with coiled-coil domains and
                     ankyrin repeats"
                     /db_xref="GeneID:55075"
                     /db_xref="HGNC:15947"
                     /db_xref="MIM:612516"
     exon            1..182
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     CDS             105..4355
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /note="isoform 1 is encoded by transcript variant 1;
                     nuclear membrane binding protein; uveal autoantigen with
                     coiled coil domains and ankyrin repeats"
                     /codon_start=1
                     /product="uveal autoantigen with coiled-coil domains and
                     ankyrin repeats isoform 1"
                     /protein_id="NP_060473.2"
                     /db_xref="GI:59850762"
                     /db_xref="CCDS:CCDS10235.1"
                     /db_xref="GeneID:55075"
                     /db_xref="HGNC:15947"
                     /db_xref="MIM:612516"
                     /translation="
MKSLKSRLRRQDVPGPASSGAAAASAHAADWNKYDDRLMKAAERGDVEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYARIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIPAHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
"
     misc_feature    216..563
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /note="ankyrin repeats;  ankyrin repeats mediate
                     protein-protein interactions in very diverse families of
                     proteins. The number of ANK repeats in a protein can range
                     from 2 to over 20 (ankyrins, for example). ANK repeats may
                     occur in combinations with other...; Region: ANK; cd00204"
                     /db_xref="CDD:29261"
     misc_feature    216..479
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:205076"
     misc_feature    216..302
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9BZF9.2);
                     Region: ANK 1"
     misc_feature    303..392
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9BZF9.2);
                     Region: ANK 2"
     misc_feature    396..764
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /note="ankyrin repeats;  ankyrin repeats mediate
                     protein-protein interactions in very diverse families of
                     proteins. The number of ANK repeats in a protein can range
                     from 2 to over 20 (ankyrins, for example). ANK repeats may
                     occur in combinations with other...; Region: ANK; cd00204"
                     /db_xref="CDD:29261"
     misc_feature    402..491
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9BZF9.2);
                     Region: ANK 3"
     misc_feature    417..695
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:205076"
     misc_feature    501..590
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9BZF9.2);
                     Region: ANK 4"
     misc_feature    600..689
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9BZF9.2);
                     Region: ANK 5"
     misc_feature    615..860
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:205076"
     misc_feature    684..>887
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /note="ankyrin repeats;  ankyrin repeats mediate
                     protein-protein interactions in very diverse families of
                     proteins. The number of ANK repeats in a protein can range
                     from 2 to over 20 (ankyrins, for example). ANK repeats may
                     occur in combinations with other...; Region: ANK; cd00204"
                     /db_xref="CDD:29261"
     misc_feature    699..788
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9BZF9.2);
                     Region: ANK 6"
     misc_feature    1824..4259
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /note="Chromosome segregation ATPases [Cell division and
                     chromosome partitioning]; Region: Smc; COG1196"
                     /db_xref="CDD:31389"
     misc_feature    2271..2273
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    2505..2507
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    3297..3299
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /citation=[5]
     exon            183..316
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     exon            317..405
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     exon            406..470
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     exon            471..528
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     exon            529..599
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     exon            600..706
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     exon            707..888
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     exon            889..926
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     exon            927..995
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     exon            996..1103
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     exon            1104..1136
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     exon            1137..1235
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     exon            1236..1272
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     exon            1273..1325
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     exon            1326..4064
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     STS             3445..3611
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /standard_name="SHGC-56623"
                     /db_xref="UniSTS:19628"
     variation       3746
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1056326"
     exon            4065..4217
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     exon            4218..4283
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     exon            4284..6857
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /inference="alignment:Splign:1.39.8"
     STS             4291..4438
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /standard_name="D15S1354"
                     /db_xref="UniSTS:4637"
     polyA_signal    4453..4458
                     /gene="UACA"
                     /gene_synonym="NUCLING"
     polyA_signal    4458..4463
                     /gene="UACA"
                     /gene_synonym="NUCLING"
     polyA_site      4478
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /experiment="experimental evidence, no additional details
                     recorded"
     polyA_signal    4928..4933
                     /gene="UACA"
                     /gene_synonym="NUCLING"
     polyA_site      4947
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /experiment="experimental evidence, no additional details
                     recorded"
     variation       5632
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:71152306"
     STS             5910..5942
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /standard_name="GDB:335751"
                     /db_xref="UniSTS:156601"
     STS             5992..6080
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /standard_name="D8S2279"
                     /db_xref="UniSTS:473907"
     STS             6042..6111
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /standard_name="D1S1423"
                     /db_xref="UniSTS:149619"
     polyA_signal    6287..6292
                     /gene="UACA"
                     /gene_synonym="NUCLING"
     polyA_site      6305
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /experiment="experimental evidence, no additional details
                     recorded"
     STS             6631..6784
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /standard_name="RH98418"
                     /db_xref="UniSTS:91735"
     variation       6777
                     /gene="UACA"
                     /gene_synonym="NUCLING"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:720519"
     polyA_signal    6831..6836
                     /gene="UACA"
                     /gene_synonym="NUCLING"
     polyA_site      6857
                     /gene="UACA"
                     /gene_synonym="NUCLING"
ORIGIN      
ggtacagcccgcgccgcctctgctgcagccgctgccgtctactccttgcgcgctggcactccgcagcctttaaggttcgcgcgggggccaggcaagagttagccatgaagagcctcaagtcccgcctgaggaggcaggacgtgcccggccccgcgtcgtctggcgccgccgccgccagcgcgcatgcagcagattggaataaatatgatgaccgattgatgaaagcagcagaaaggggggatgtagaaaaagtgacctcaatccttgctaaaaagggggtcaatccaggcaaactagatgtggaaggcagatctgtcttccatgttgtgacctcaaaggggaatcttgagtgtttgaatgccatccttatacatggagttgatattacaaccagtgacactgcagggagaaatgctcttcacctggctgctaagtatggacatgcattgtgcctacaaaaacttctacagtacaattgtcccactgagcatgcagacctgcagggaagaactgcacttcacgatgccgcaatggcagattgtccttctagcatacagctgctttgtgaccatggggcctctgtgaatgccaaagatgtagacgggcggacaccacttgttctggctactcagatgagtaggccaacaatatgtcaactgctgatagatagaggagcggatgttaattccagagacaaacaaaacagaactgccctcatgctaggttgcgaatatggttgcagagatgcagtagaagtcttaattaaaaatggtgctgatataagcttgctggatgcgcttggccatgatagttcttactatgcaagaattggtgacaatctggacattctaaccttgttgaagactgcatcggaaaataccaacaaagggagagaactttggaagaaagggccatctttgcaacagcgaaatttgacacacatgcaagatgaagtaaatgtgaagtcacatcagagggagcatcaaaatattcaggatttggagattgaaaatgaagatttgaaagagaggttgagaaaaattcagcaagaacaaagaatacttttggataaagtcaatggtttacagttacagctgaatgaggaagttatggttgctgatgatctggaaagcgagagagaaaagctgaagtcccttttggcagctaaagaaaagcaacatgaagaaagcttaaggactattgaggctctgaaaaatagatttaaatattttgagagtgatcatttaggatcaggaagtcatttcagtaaccgaaaagaagatatgcttcttaaacaaggtcagatgtatatggcagactcacagtgtacttccccaggtataccagcccatatgcaaagcagatctatgttaagacctctggaactatctttacccagtcaaacgtcatactctgaaaatgaaattttaaagaaagagttagaagcaatgcgaactttctgtgagtcagcaaaacaagaccgactgaagctccaaaatgaactggcacacaaagtggcagaatgcaaagctttagcattagaatgtgaaagggtcaaggaggattcagatgaacagataaagcaattagaagatgcattaaaagatgtgcagaagaggatgtatgagtcagaaggtaaagttaaacaaatgcagacccattttcttgcccttaaagaacacttaacaagtgaagcagcctcagggaatcacagactaaccgaggaactgaaggatcagttgaaagacttgaaagtaaaatatgaaggtgcttcagcagaagtggggaaattaagaaaccaaatcaaacaaaatgagatgatagtagaagagtttaagagggatgaaggcaagctgatagaagaaaataagcgattacagaaggaacttagtatgtgtgaaatggagcgagagaagaaaggaagaaaggtcacagagatggaaggccaggcaaaagaattgtcagcgaagttggccctttccattccagctgaaaaatttgaaaacatgaagagctcattatcaaatgaagtgaatgagaaagcaaaaaaattagtagaaatggaaagagaacatgaaaaatcacttagtgaaattagacagttaaagagagaacttgagaatgttaaggccaagcttgctcagcacgtcaaaccagaggaacatgaacaggttaagagcagattagaacagaaatcaggagaacttgggaagaagatcactgagttaacattgaaaaatcagacactacaaaaggaaattgaaaaagtttatttggataataagctcctcaaggagcaagcacataacttaacaattgaaatgaaaaatcattatgttcctttaaaagtaagtgaagacatgaaaaagtcacatgatgcaattattgatgatcttaatagaaagcttttagatgtaacacaaaaatatacagaaaagaagttggaaatggagaaattgctactggaaaatgacagcttaagtaaggatgtaagccgcctagaaactgtgtttgtacctcctgagaaacatgaaaaagagataatagctctgaaatccaatattgttgaacttaagaaacagctgtctgaacttaagaaaaaatgtggtgaagaccaggagaaaatacacgctctcacatctgaaaacactaacttgaagaagatgatgagtaatcagtatgtgccagttaaaacccatgaagaggttaaaatgacactgaatgacacgttagccaaaactaacagagaattattagatgtgaagaaaaaatttgaagatataaatcaggaatttgtaaaaataaaagataagaatgaaatattaaaaagaaacctggaaaacactcagaaccaaataaaagctgagtacatcagcctggcagagcacgaggcaaagatgagctcgctaagtcagagcatgagaaaggtgcaggatagtaatgctgaaatcttggccaactacagaaaaggccaagaagagattgtgacactgcatgccgaaattaaagcccagaagaaggagctcgacacaatacaagaatgcattaaggtaaaatacgccccaattgtcagctttgaggagtgcgagagaaaatttaaagcaacagagaaagaactaaaagaccagttatcagagcagacacaaaagtatagtgtcagtgaagaagaagtcaagaaaaacaagcaagagaatgacaagttaaagaaggagatttttacccttcagaaagatttgagagataagacagttctcattgagaagtctcatgaaatggaaagagcattaagcagaaaaacagacgagctaaacaaacagttaaaagacttgtcacagaaatacacggaagtaaagaatgtgaaagagaagctagtagaagaaaatgccaaacagacttctgagatacttgcagtgcaaaatcttttgcaaaaacaacatgttccattggaacaggttgaggctctgaaaaaatctcttaatggcacaattgaaaatctaaaggaagaactgaagagtatgcaaaggtgttacgagaaagagcagcagacagtgaccaaactgcatcaattgttggagaatcaaaagaactcttctgtacccctggcagagcatttgcagattaaagaagcatttgagaaagaagttggaatcataaaagccagcttgagagaaaaggaagaagaaagccaaaacaaaatggaagaagtctccaaacttcagtcggaggttcagaatactaaacaagcattaaaaaaattagagactagagaggtagttgacttgtctaaatataaagcaacaaaaagtgatttggagacacagatttctagcttaaatgaaaaattggccaatctgaatagaaagtatgaggaagtatgtgaggaagttttgcatgccaaaaagaaggaaatatctgcaaaagatgagaaggaattactgcatttcagcattgagcaagaaattaaggatcagaaggaacgatgtgataagtccttaacaacaatcacagagttacaaagaagaatacaagaatctgctaaacaaatagaagcaaaagataataagataactgaactgcttaatgatgtggaaagattaaaacaggcactcaatggcctttcccaactcacctacacaagtgggaaccccaccaagaggcagagccagctgattgacactctgcagcaccaagtgaaatctctggagcaacagctggccgatgctgacagacagcaccaagaagtaattgcaatttatcggacacaccttcttagtgctgcacagggtcacatggatgaagatgttcaggaggctctgctccagatcatacaaatgcggcaggggcttgtgtgctagccgttagcactgactgccagtatctgttttatcttgctggtgctgaacattctttgtgcaactccatggtctttctgggccttactgtgctggtataattaaaataaaatatattttgttctattggtaggtttttttttaaaattagatgaatatgttagtctttttcaatatcagtttgaatcttattttctgtatgtgttaattttacaaataggcaaacaacataactttgccctggattgactacatatttttaaaccttcaagtccctaataaaacatgagccatctgagtgagtccatatgaagcgaggttaggctgaaataattgcttaaagatgtctttcagagaaattaatttggttggtggccacttttaggtggatcaaaagacctttcagatcctcagaaccttgagacataatacagttgtgaggaatgtgttgtaacttggctggccaagttacatgttacagtatctttactgaggtaacttcattagtgtctttggccttttttgtaggtatagatattttttctttttacactaataacttttatgccttttaaaataaatttattttcataaatggtttgcagtgctaaattacatttagattaagaacaggcaggggtggaatatatcaggaatttataataaaattgccttaatctctacaacagtatcttaatttttacttgcggtgactattcttgccacaatattggagaataatgatagatgatatactagatttttcaaagtgtgaaaacctttagactttttttagcaattagtttgacattcgctactatagtaaccaagcactcattatatatgcatcctccaaatgtttcatgcttatttataggaaagttatattaatgagattaataatgtgaaatacagttttcctgcaaaattagcattagagaattgattttagataacagatttttaaagttttagagaaaagtacagtaatacagtaaactgaaagagtatatagatagcaataaaataacataagtggacatgtttatagtaaatactctgaagtaaacaaccgtttttattaactgcatctcattagggaaagtttatatgtcttgttattttttattaacattttatttaccattcagagtgaaaattactaatttgagtattaacaaataactgaataaatggatcattacagttaggttttctcaaattgcaaaatttgccttagcaattatctttgaacatcccgaaccagatttttaaatcccatttttgtttaatagggtaaaaataccatcaaaatgacttctcataccaaagaataagccatcatattttttcggtgttgaaacaacattgaaagtcagaattggatttgtttttaattctttatacggtttacataagcaatatctgtctctttaattattatgattaatgtcgtccttcagcatgagttctgtttcacaagttttgggccacctatttcaataaaaaataaaatataaattaaaaaagttgccgggggtggtggctcatgcctgtaatcccagcactttgggaggctgagggaggtagatcacctgaggtcagaagttcgagaccagccttaccaatatggtgaagccccatctctactaaaaatacaaaaattagccctgcatggtggcaggtgcctgtagtcccaggtactcgggaggctgagacaggagaatcgcttgaacctgggaggcggaggttgcagtgagccaagatctcgccactgcactccagcttgggcaatagcaagactccatctcaaaataaaataaaataaaacttagagcaaagtttaaaactgagtattcatattaagtgttttattttccatattagagatgggaagggaaccttatgtgtattttattttgttttcaaccatcaataaagttttctctagaatattgttttgaacatccttgtaaaagatttgcgagttaaactattttatttactgtctgtgagagcattgggagtaggaaacgatggactccaaagtacaagggagaatacccattttcattcagctatctggagtaaaatatcaagtacttccttcaactaatcttgtctcattcactcaccttttgatatcgaaggcagaaattgcgtttacaacactgaagaccaaagctttttaattagtaaacaagcggaacatagataatggacaatgctggccactgccattctgtgttcagaaagactatgagacctgaacatatggccaagaggaaagaagagtgacgttgtctaagatgtaatgagtgctctctgagagaatcactcaattcctattggagtgcaatccttacttgagaactttattactcttgttctgtgtagttttttttttttgtcacttccccatcagaaaagcatattctttttgatagagggtcagtgttataaataattgtcttttgaaataaaatcaaatattcatgcattgaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:55075 -> Molecular function: GO:0003674 [molecular_function] evidence: ND
            GeneID:55075 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:55075 -> Biological process: GO:0008150 [biological_process] evidence: ND
            GeneID:55075 -> Biological process: GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage] evidence: IEA
            GeneID:55075 -> Biological process: GO:0008631 [intrinsic apoptotic signaling pathway in response to oxidative stress] evidence: IEA
            GeneID:55075 -> Biological process: GO:0009411 [response to UV] evidence: IEA
            GeneID:55075 -> Biological process: GO:0042307 [positive regulation of protein import into nucleus] evidence: IEA
            GeneID:55075 -> Biological process: GO:0042347 [negative regulation of NF-kappaB import into nucleus] evidence: IEA
            GeneID:55075 -> Biological process: GO:0043065 [positive regulation of apoptotic process] evidence: IEA
            GeneID:55075 -> Biological process: GO:0043280 [positive regulation of cysteine-type endopeptidase activity involved in apoptotic process] evidence: IEA
            GeneID:55075 -> Biological process: GO:0050728 [negative regulation of inflammatory response] evidence: IEA
            GeneID:55075 -> Cellular component: GO:0005576 [extracellular region] evidence: NAS
            GeneID:55075 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:55075 -> Cellular component: GO:0005635 [nuclear envelope] evidence: IEA
            GeneID:55075 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
            GeneID:55075 -> Cellular component: GO:0005739 [mitochondrion] evidence: IDA
            GeneID:55075 -> Cellular component: GO:0005856 [cytoskeleton] evidence: IEA
            GeneID:55075 -> Cellular component: GO:0016020 [membrane] evidence: IEA
            GeneID:55075 -> Cellular component: GO:0043293 [apoptosome] evidence: IEA
            GeneID:55075 -> Cellular component: GO:0048471 [perinuclear region of cytoplasm] evidence: IEA

by @meso_cacase at DBCLS
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