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2024-04-20 14:16:18, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_016428               2129 bp    mRNA    linear   PRI 15-JUN-2013
DEFINITION  Homo sapiens ABI family, member 3 (ABI3), transcript variant 1,
            mRNA.
ACCESSION   NM_016428
VERSION     NM_016428.2  GI:29337288
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2129)
  AUTHORS   Lauc,G., Huffman,J.E., Pucic,M., Zgaga,L., Adamczyk,B., Muzinic,A.,
            Novokmet,M., Polasek,O., Gornik,O., Kristic,J., Keser,T.,
            Vitart,V., Scheijen,B., Uh,H.W., Molokhia,M., Patrick,A.L.,
            McKeigue,P., Kolcic,I., Lukic,I.K., Swann,O., van Leeuwen,F.N.,
            Ruhaak,L.R., Houwing-Duistermaat,J.J., Slagboom,P.E., Beekman,M.,
            de Craen,A.J., Deelder,A.M., Zeng,Q., Wang,W., Hastie,N.D.,
            Gyllensten,U., Wilson,J.F., Wuhrer,M., Wright,A.F., Rudd,P.M.,
            Hayward,C., Aulchenko,Y., Campbell,H. and Rudan,I.
  TITLE     Loci associated with N-glycosylation of human immunoglobulin G show
            pleiotropy with autoimmune diseases and haematological cancers
  JOURNAL   PLoS Genet. 9 (1), E1003225 (2013)
   PUBMED   23382691
REFERENCE   2  (bases 1 to 2129)
  AUTHORS   Latini,F.R., Hemerly,J.P., Freitas,B.C., Oler,G., Riggins,G.J. and
            Cerutti,J.M.
  TITLE     ABI3 ectopic expression reduces in vitro and in vivo cell growth
            properties while inducing senescence
  JOURNAL   BMC Cancer 11, 11 (2011)
   PUBMED   21223585
  REMARK    GeneRIF: Result links ABI3 to the pathogenesis and progression of
            some cancers and suggests that ABI3 or its pathway might have
            interest as therapeutic target.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2129)
  AUTHORS   Venkatesan,K., Rual,J.F., Vazquez,A., Stelzl,U., Lemmens,I.,
            Hirozane-Kishikawa,T., Hao,T., Zenkner,M., Xin,X., Goh,K.I.,
            Yildirim,M.A., Simonis,N., Heinzmann,K., Gebreab,F., Sahalie,J.M.,
            Cevik,S., Simon,C., de Smet,A.S., Dann,E., Smolyar,A.,
            Vinayagam,A., Yu,H., Szeto,D., Borick,H., Dricot,A., Klitgord,N.,
            Murray,R.R., Lin,C., Lalowski,M., Timm,J., Rau,K., Boone,C.,
            Braun,P., Cusick,M.E., Roth,F.P., Hill,D.E., Tavernier,J.,
            Wanker,E.E., Barabasi,A.L. and Vidal,M.
  TITLE     An empirical framework for binary interactome mapping
  JOURNAL   Nat. Methods 6 (1), 83-90 (2009)
   PUBMED   19060904
REFERENCE   4  (bases 1 to 2129)
  AUTHORS   Hirao,N., Sato,S., Gotoh,T., Maruoka,M., Suzuki,J., Matsuda,S.,
            Shishido,T. and Tani,K.
  TITLE     NESH (Abi-3) is present in the Abi/WAVE complex but does not
            promote c-Abl-mediated phosphorylation
  JOURNAL   FEBS Lett. 580 (27), 6464-6470 (2006)
   PUBMED   17101133
  REMARK    GeneRIF: NESH (Abi-3), like Abi-1 and Abi-2, is a component of the
            Abi/WAVE complex, but likely plays a different role in the
            regulation of c-Abl.
REFERENCE   5  (bases 1 to 2129)
  AUTHORS   Ichigotani,Y., Fujii,K., Hamaguchi,M. and Matsuda,S.
  TITLE     In search of a function for the E3B1/Abi2/Argbp1/NESH family
            (Review)
  JOURNAL   Int. J. Mol. Med. 9 (6), 591-595 (2002)
   PUBMED   12011975
  REMARK    Review article
REFERENCE   6  (bases 1 to 2129)
  AUTHORS   Ichigotani,Y., Yokozaki,S., Fukuda,Y., Hamaguchi,M. and Matsuda,S.
  TITLE     Forced expression of NESH suppresses motility and metastatic
            dissemination of malignant cells
  JOURNAL   Cancer Res. 62 (8), 2215-2219 (2002)
   PUBMED   11956071
  REMARK    GeneRIF: Forced expression of NESH suppresses motility and
            metastatic dissemination of malignant cells.
REFERENCE   7  (bases 1 to 2129)
  AUTHORS   Matsuda,S., Iriyama,C., Yokozaki,S., Ichigotani,Y., Shirafuji,N.,
            Yamaki,K., Hayakawa,T. and Hamaguchi,M.
  TITLE     Cloning and sequencing of a novel human gene that encodes a
            putative target protein of Nesh-SH3
  JOURNAL   J. Hum. Genet. 46 (8), 483-486 (2001)
   PUBMED   11501947
REFERENCE   8  (bases 1 to 2129)
  AUTHORS   Miyazaki,K., Matsuda,S., Ichigotani,Y., Takenouchi,Y., Hayashi,K.,
            Fukuda,Y., Nimura,Y. and Hamaguchi,M.
  TITLE     Isolation and characterization of a novel human gene (NESH) which
            encodes a putative signaling molecule similar to e3B1 protein
  JOURNAL   Biochim. Biophys. Acta 1493 (1-2), 237-241 (2000)
   PUBMED   10978530
REFERENCE   9  (bases 1 to 2129)
  AUTHORS   Simpson,J.C., Wellenreuther,R., Poustka,A., Pepperkok,R. and
            Wiemann,S.
  TITLE     Systematic subcellular localization of novel proteins identified by
            large-scale cDNA sequencing
  JOURNAL   EMBO Rep. 1 (3), 287-292 (2000)
   PUBMED   11256614
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AB037886.1.
            On Mar 28, 2003 this sequence version replaced gi:7705980.
            
            Summary: This gene encodes a member of an adaptor protein family.
            Members of this family encode proteins containing a homeobox
            homology domain, proline rich region and Src-homology 3 (SH3)
            domain, and are components of the Abi/WAVE complex which regulates
            Rac-dependent actin polymerization. The encoded protein inhibits
            ectopic metastasis of tumor cells as well as cell migration. This
            may be accomplished through interaction with p21-activated kinase.
            [provided by RefSeq, Sep 2008].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB037886.1, AL136709.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025085, ERS025086 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..2129
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q21.3"
     gene            1..2129
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /note="ABI family, member 3"
                     /db_xref="GeneID:51225"
                     /db_xref="HGNC:29859"
                     /db_xref="HPRD:05900"
                     /db_xref="MIM:606363"
     exon            1..615
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /inference="alignment:Splign:1.39.8"
     variation       63
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2233364"
     misc_feature    94..96
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /note="upstream in-frame stop codon"
     variation       94
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149838793"
     variation       107
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:12948271"
     variation       250..261
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace=""
                     /replace="tgggcccccaaa"
                     /db_xref="dbSNP:140527653"
     variation       344
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:73338394"
     variation       387
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:188837768"
     variation       388
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:377689573"
     variation       445
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:192806498"
     variation       464
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2233365"
     CDS             499..1599
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /note="isoform 1 is encoded by transcript variant 1; ABI
                     gene family, member 3; new molecule including SH3; ABI
                     gene family member 3"
                     /codon_start=1
                     /product="ABI gene family member 3 isoform 1"
                     /protein_id="NP_057512.1"
                     /db_xref="GI:7705981"
                     /db_xref="CCDS:CCDS11546.1"
                     /db_xref="GeneID:51225"
                     /db_xref="HGNC:29859"
                     /db_xref="HPRD:05900"
                     /db_xref="MIM:606363"
                     /translation="
MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALASVAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPPGQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVEPSC
"
     misc_feature    775..996
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /note="Abl-interactor HHR; Region: Abi_HHR; pfam07815"
                     /db_xref="CDD:149081"
     misc_feature    1432..1587
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /note="Src homology 3 domain of Abl Interactor proteins;
                     Region: SH3_Abi; cd11826"
                     /db_xref="CDD:212760"
     misc_feature    order(1447..1449,1453..1455,1462..1464,1474..1476,
                     1528..1533,1570..1572,1576..1581)
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /note="peptide ligand binding site [polypeptide binding];
                     other site"
                     /db_xref="CDD:212760"
     variation       511
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143414853"
     variation       544
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370923583"
     variation       564
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376299895"
     variation       574
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201115503"
     variation       598
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146754613"
     exon            616..783
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /inference="alignment:Splign:1.39.8"
     variation       628
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200790496"
     variation       629
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2233369"
     variation       635
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143540619"
     variation       649
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143614623"
     variation       652
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200111501"
     variation       707
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371444697"
     variation       723
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201757928"
     variation       742
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374915787"
     variation       755
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:199999962"
     variation       759
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35031462"
     variation       763
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369657954"
     exon            784..960
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /inference="alignment:Splign:1.39.8"
     variation       788
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202087269"
     variation       794
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377358127"
     variation       813
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145273532"
     variation       831
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:117896869"
     variation       838
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:187673177"
     variation       841
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:201557264"
     variation       845
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142527437"
     variation       848
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:137924898"
     variation       868
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139297199"
     variation       955
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370412209"
     exon            961..1046
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /inference="alignment:Splign:1.39.8"
     variation       990
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:73340306"
     variation       1020
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2233371"
     exon            1047..1142
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /inference="alignment:Splign:1.39.8"
     variation       1121
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199635084"
     variation       1124
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:616338"
     exon            1143..1300
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /inference="alignment:Splign:1.39.8"
     variation       1143
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147987389"
     variation       1149
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:76617033"
     variation       1159
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200867869"
     variation       1164
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376591517"
     variation       1174
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150532080"
     variation       1180
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369790283"
     variation       1210
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139539456"
     variation       1217
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368043560"
     variation       1229
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:371508417"
     variation       1248
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:375202610"
     variation       1269
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:141746983"
     exon            1301..1435
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /inference="alignment:Splign:1.39.8"
     variation       1302
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146244763"
     variation       1303
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200803220"
     variation       1326
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371106947"
     variation       1336
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139368451"
     variation       1342
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:144160707"
     variation       1349
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:145120343"
     variation       1357
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199538050"
     variation       1417
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:373253578"
     variation       1426
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:377169529"
     variation       1428
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:370459926"
     exon            1436..2109
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /inference="alignment:Splign:1.39.8"
     variation       1441
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150100821"
     variation       1452
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142832429"
     variation       1514
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201030368"
     variation       1524
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:151062169"
     variation       1542
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368794979"
     variation       1543
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200202572"
     variation       1603
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2233374"
     variation       1624
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:368644987"
     variation       1634
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371956623"
     variation       1918
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:114842800"
     variation       1921
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:187442799"
     variation       1946
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:191319602"
     variation       1991..1992
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:34526681"
     variation       1993
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:183237512"
     variation       1995
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11545136"
     variation       2077
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:56327802"
     polyA_site      2109
                     /gene="ABI3"
                     /gene_synonym="NESH; SSH3BP3"
                     /experiment="experimental evidence, no additional details
                     recorded"
ORIGIN      
tcctatccaccctccactcccctgtcccttggtgactcatccctgagcttcccaaggaagcccccaccctctgccctttcctcccgccttccatgagtggaaaatccacctccgccccctatagcaggccagcccccttcctccccagtctccgaccccatcccccagccgaccagtttcctctccaggaccagggagcaatcacagctgccccgaccttggcttcctctgctgggtgggattgggggctgggcccccaaatgggcccctggcttcccccttcctctgggcaggggacagagagacacaggctcggggagcaggactgacttcctcttgtcccggaatgagcatgcctgccctttgcaagcaggtttgggtctcacgcagaggaaaccaaaagcaataagagggagggaaggcagagcaaccaatcaagggcagggtgagactcaaaacgagcgggctccctggggagccagacagaggctgggggtgatggcggagctacagcagctgcaggagtttgagatccccactggccgggaggctctgaggggcaaccacagtgccctgctgcgggtcgctgactactgcgaggacaactatgtgcaggccacagacaagcggaaggcgctggaggagaccatggccttcactacccaggcactggccagcgtggcctaccaggtgggcaacctggccgggcacactctgcgcatgttggacctgcagggggccgccctgcggcaggtggaagcccgtgtaagcacgctgggccagatggtgaacatgcatatggagaaggtggcccgaagggagatcggcaccttagccactgtccagcggctgccccccggccagaaggtcatcgccccagagaacctaccccctctcacgccctactgcaggagacccctcaactttggctgcctggacgacattggccatgggatcaaggacctcagcacgcagctgtcaagaacaggcaccctgtctcgaaagagcatcaaggcccctgccacacccgcctccgccaccttggggagaccaccccggattcccgagccagtgcacctgccggtggtgcccgacggcagactctccgccgcctcctctgcgtcttccctggcctcggccggcagcgccgaaggtgtcggtggggcccccacgcccaaggggcaggcagcacctccagccccacctctccccagctccttggacccacctcctccaccagcagccgtcgaggtgttccagcggcctcccacgctggaggagttgtccccacccccaccggacgaagagctgcccctgccactggacctgcctcctcctccacccctggatggagatgaattggggctgcctccacccccaccaggatttgggcctgatgagcccagctgggtgcctgcctcatacttggagaaagtggtgacactgtacccatacaccagccagaaggacaatgagctctccttctctgagggcactgtcatctgtgtcactcgccgctactccgatggctggtgcgagggcgtcagctcagaggggactggattcttccctgggaactatgtggagcccagctgctgacagcccagggctctctgggcagctgatgtctgcactgagtgggtttcatgagccccaagccaaaaccagctccagtcacagctggactgggtctgcccacctcttgggctgtgagctgtgttctgtccttcctcccatcggagggagaaggggtcctggggagagagaatttatccagaggcctgctgcagatggggaagagctggaaaccaagaagtttgtcaacagaggacccctactccatgcaggacagggtctcctgctgcaagtcccaactttgaataaaacagatgatgtcctgtgactgccccacagagataaggggccaggagggattgaaaggcatcccagttctaaggctgctgctaattacagcccccaacctccaacccaccagctgacctagaagcagcatcttcccatttcctcagtacccacaaagtgcagcccacattggaccccagacacccctctgcagccattgactgcaacttgttcttttgcccattgaaaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:51225 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:51225 -> Biological process: GO:0006928 [cellular component movement] evidence: NAS
            GeneID:51225 -> Biological process: GO:0018108 [peptidyl-tyrosine phosphorylation] evidence: IDA
            GeneID:51225 -> Biological process: GO:0030334 [regulation of cell migration] evidence: IDA
            GeneID:51225 -> Cellular component: GO:0005622 [intracellular] evidence: IDA
            GeneID:51225 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
            GeneID:51225 -> Cellular component: GO:0005737 [cytoplasm] evidence: NAS
            GeneID:51225 -> Cellular component: GO:0030027 [lamellipodium] evidence: IDA

by @meso_cacase at DBCLS
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