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2024-04-19 15:51:46, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_015548 16652 bp mRNA linear PRI 29-APR-2013
DEFINITION Homo sapiens dystonin (DST), transcript variant 1eA, mRNA.
ACCESSION NM_015548 XM_003118556 XM_003120004 XM_003120523
VERSION NM_015548.4 GI:291290967
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 16652)
AUTHORS Pasdeloup,D., McElwee,M., Beilstein,F., Labetoulle,M. and
Rixon,F.J.
TITLE Herpesvirus tegument protein pUL37 interacts with dystonin/BPAG1 to
promote capsid transport on microtubules during egress
JOURNAL J. Virol. 87 (5), 2857-2867 (2013)
PUBMED 23269794
REMARK GeneRIF: study identifies dystonin, a cytoskeleton cross-linker
involved in microtubule-based transport, as a binding partner of
the HSV-1 protein pUL37, implicated in capsid transport; study
provides insight into cellular requirements for HSV-1 capsid
transport and identifies dystonin as a nonmotor protein part of
transport machinery
REFERENCE 2 (bases 1 to 16652)
AUTHORS Edvardson,S., Cinnamon,Y., Jalas,C., Shaag,A., Maayan,C.,
Axelrod,F.B. and Elpeleg,O.
TITLE Hereditary sensory autonomic neuropathy caused by a mutation in
dystonin
JOURNAL Ann. Neurol. 71 (4), 569-572 (2012)
PUBMED 22522446
REMARK GeneRIF: This is the first report of a defect in the neuronal
isoform of dystonin in humans.
REFERENCE 3 (bases 1 to 16652)
AUTHORS Hamill,K.J., Hopkinson,S.B., Jonkman,M.F. and Jones,J.C.
TITLE Type XVII collagen regulates lamellipod stability, cell motility,
and signaling to Rac1 by targeting bullous pemphigoid antigen 1e to
alpha6beta4 integrin
JOURNAL J. Biol. Chem. 286 (30), 26768-26780 (2011)
PUBMED 21642434
REMARK GeneRIF: in motile cells Col XVII recruits BPAG1e to alpha6beta4
integrin and is necessary for activation of signaling pathways,
motile behavior, and lamellipodial stability.
REFERENCE 4 (bases 1 to 16652)
AUTHORS Steiner-Champliaud,M.F., Schneider,Y., Favre,B., Paulhe,F.,
Praetzel-Wunder,S., Faulkner,G., Konieczny,P., Raith,M., Wiche,G.,
Adebola,A., Liem,R.K., Langbein,L., Sonnenberg,A., Fontao,L. and
Borradori,L.
TITLE BPAG1 isoform-b: complex distribution pattern in striated and heart
muscle and association with plectin and alpha-actinin
JOURNAL Exp. Cell Res. 316 (3), 297-313 (2010)
PUBMED 19932097
REMARK GeneRIF: BPAG1-b was detectable in vitro and in vivo as a high
molecular mass protein in striated and heart muscle cells,
co-localizing with alpha-actinin-2 and partially with the
cytolinker plectin as well as with the intermediate filament
protein desmin.
REFERENCE 5 (bases 1 to 16652)
AUTHORS Okumura,M., Yamakawa,H., Ohara,O. and Owaribe,K.
TITLE Novel alternative splicings of BPAG1 (bullous pemphigoid antigen 1)
including the domain structure closely related to MACF (microtubule
actin cross-linking factor)
JOURNAL J. Biol. Chem. 277 (8), 6682-6687 (2002)
PUBMED 11751855
REFERENCE 6 (bases 1 to 16652)
AUTHORS Brown,A., Dalpe,G., Mathieu,M. and Kothary,R.
TITLE Cloning and characterization of the neural isoforms of human
dystonin
JOURNAL Genomics 29 (3), 777-780 (1995)
PUBMED 8575775
REFERENCE 7 (bases 1 to 16652)
AUTHORS Sawamura,D., Li,K., Chu,M.L. and Uitto,J.
TITLE Human bullous pemphigoid antigen (BPAG1). Amino acid sequences
deduced from cloned cDNAs predict biologically important peptide
segments and protein domains
JOURNAL J. Biol. Chem. 266 (27), 17784-17790 (1991)
PUBMED 1717441
REFERENCE 8 (bases 1 to 16652)
AUTHORS Tanaka,T., Parry,D.A., Klaus-Kovtun,V., Steinert,P.M. and
Stanley,J.R.
TITLE Comparison of molecularly cloned bullous pemphigoid antigen to
desmoplakin I confirms that they define a new family of cell
adhesion junction plaque proteins
JOURNAL J. Biol. Chem. 266 (19), 12555-12559 (1991)
PUBMED 1712022
REFERENCE 9 (bases 1 to 16652)
AUTHORS Sawamura,D., Li,K.H., Nomura,K., Sugita,Y., Christiano,A.M. and
Uitto,J.
TITLE Bullous pemphigoid antigen: cDNA cloning, cellular expression, and
evidence for polymorphism of the human gene
JOURNAL J. Invest. Dermatol. 96 (6), 908-915 (1991)
PUBMED 2045679
REFERENCE 10 (bases 1 to 16652)
AUTHORS Sawamura,D., Nomura,K., Sugita,Y., Mattei,M.G., Chu,M.L.,
Knowlton,R. and Uitto,J.
TITLE Bullous pemphigoid antigen (BPAG1): cDNA cloning and mapping of the
gene to the short arm of human chromosome 6
JOURNAL Genomics 8 (4), 722-726 (1990)
PUBMED 2276744
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DA462108.1, AF400226.1,
L11690.1, AL512448.9, AK055189.1, AL137008.9 and CD367397.1.
This sequence is a reference standard in the RefSeqGene project.
On or before May 6, 2011 this sequence version replaced
gi:310119786, gi:310128340, gi:310115031, gi:148613860.
Summary: This gene encodes a member of the plakin protein family of
adhesion junction plaque proteins. Multiple alternatively spliced
transcript variants encoding distinct isoforms have been found for
this gene, but the full-length nature of some variants has not been
defined. It has been reported that some isoforms are expressed in
neural and muscle tissue, anchoring neural intermediate filaments
to the actin cytoskeleton, and some isoforms are expressed in
epithelial tissue, anchoring keratin-containing intermediate
filaments to hemidesmosomes. Consistent with the expression, mice
defective for this gene show skin blistering and neurodegeneration.
[provided by RefSeq, Mar 2010].
Transcript Variant: This variant (1eA) contains an alternate exon
in the 5' UTR, lacks a portion of the 5' coding region, and
initiates translation at an alternate start codon, compared to
variant 2. The encoded isoform (1eA) has a shorter and distinct
N-terminus compared to isoform 2.
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AF400226.1 [ECO:0000332]
##Evidence-Data-END##
COMPLETENESS: full length.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-108 DA462108.1 1-108
109-1871 AF400226.1 1-1763
1872-3217 L11690.1 1866-3211
3218-7960 AF400226.1 3110-7852
7961-8547 AL512448.9 54594-55180 c
8548-10954 AK055189.1 1278-3684
10955-11428 AF400226.1 10847-11320
11429-11429 AL512448.9 10688-10688 c
11430-12190 AF400226.1 11322-12082
12191-12191 AL512448.9 108-108 c
12192-13519 AF400226.1 12084-13411
13520-13520 AL137008.9 51847-51847 c
13521-14429 AF400226.1 13413-14321
14430-14430 AL137008.9 40279-40279 c
14431-16390 AF400226.1 14323-16282
16391-16652 CD367397.1 7-268 c
FEATURES Location/Qualifiers
source 1..16652
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="6"
/map="6p12.1"
gene 1..16652
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="dystonin"
/db_xref="GeneID:667"
/db_xref="HGNC:1090"
/db_xref="HPRD:00222"
/db_xref="MIM:113810"
misc_feature 61..63
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="upstream in-frame stop codon"
CDS 109..15624
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="isoform 1eA precursor is encoded by transcript
variant 1eA; bullous pemphigoid antigen 1, 230/240kDa;
hemidesmosomal plaque protein; trabeculin-beta; dystonia
musculorum protein"
/codon_start=1
/product="bullous pemphigoid antigen 1 isoform 1eA
precursor"
/protein_id="NP_056363.2"
/db_xref="GI:34577049"
/db_xref="CCDS:CCDS47443.1"
/db_xref="GeneID:667"
/db_xref="HGNC:1090"
/db_xref="HPRD:00222"
/db_xref="MIM:113810"
/translation="
MHSSSYSYRSSDSVFSNTTSTRTSLDSNENLLLVHCGPTLINSCISFGSESFDGHRLEMLQQIANRVQRDSVICEDKLILAGNALQSDSKRLESGVQFQNEAEIAGYILECENLLRQHVIDVQILIDGKYYQADQLVQRVAKLRDEIMALRNECSSVYSKGRILTTEQTKLMISGITQSLNSGFAQTLHPSLTSGLTQSLTPSLTSSSMTSGLSSGMTSRLTPSVTPAYTPGFPSGLVPNFSSGVEPNSLQTLKLMQIRKPLLKSSLLDQNLTEEEINMKFVQDLLNWVDEMQVQLDRTEWGSDLPSVESHLENHKNVHRAIEEFESSLKEAKISEIQMTAPLKLTYAEKLHRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTNIARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPARLTIEAYRAAMQTQWSWILQLCQCVEQHIKENTAYFEFFNDAKEATDYLRNLKDAIQRKYSCDRSSSIHKLEDLVQESMEEKEELLQYKSTIANLMGKAKTIIQLKPRNSDCPLKTSIPIKAICDYRQIEITIYKDDECVLANNSHRAKWKVISPTGNEAMVPSVCFTVPPPNKEAVDLANRIEQQYQNVLTLWHESHINMKSVVSWHYLINEIDRIRASNVASIKTMLPGEHQQVLSNLQSRFEDFLEDSQESQVFSGSDITQLEKEVNVCKQYYQELLKSAEREEQEESVYNLYISEVRNIRLRLENCEDRLIRQIRTPLERDDLHESVFRITEQEKLKKELERLKDDLGTITNKCEEFFSQAAASSSVPTLRSELNVVLQNMNQVYSMSSTYIDKLKTVNLVLKNTQAAEALVKLYETKLCEEEAVIADKNNIENLISTLKQWRSEVDEKRQVFHALEDELQKAKAISDEMFKTYKERDLDFDWHKEKADQLVERWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENSKTLATQLNQQKMLVSEIEMKQSKMDECQKYAEQYSATVKDYELQTMTYRAMVDSQQKSPVKRRRMQSSADLIIQEFMDLRTRYTALVTLMTQYIKFAGDSLKRLEEEEKSLEEEKKEHVEKAKELQKWVSNISKTLKDAEKAGKPPFSKQKISSEEISTKKEQLSEALQTIQLFLAKHGDKMTDEERNELEKQVKTLQESYNLLFSESLKQLQESQTSGDVKVEEKIVAERQQEYKEKLQGICDLLTQTENRLIGHQEAFMIGDGTVELKKYQSKQEELQKDMQGSAQALAEVVKNTENFLKENGEKLSQEDKALIEQKLNEAKIKCEQLNLKAEQSKKELDKVVTTAIKEETEKVAAVKQLEESKTKIENLLDWLSNVDKDSERAGTKHKQVIEQNGTHFQEGDGKSAIGEEDEVNGNLLETDVDGQVGTTQENLNQQYQKVKAQHEKIISQHQAVIIATQSAQVLLEKQGQYLSPEEKEKLQKNMKELKVHYETALAESEKKMKLTHSLQEELEKFDADYTEFEHWLQQSEQELENLEAGADDINGLMTKLKRQKSFSEDVISHKGDLRYITISGNRVLEAAKSCSKRDGGKVDTSATHREVQRKLDHATDRFRSLYSKCNVLGNNLKDLVDKYQHYEDASCGLLAGLQACEATASKHLSEPIAVDPKNLQRQLEETKALQGQISSQQVAVEKLKKTAEVLLDARGSLLPAKNDIQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGLDEMLDWMGNVESSLKEQGQVPLNSTALQDIISKNIMLEQDIAGRQSSINAMNEKVKKFMETTDPSTASSLQAKMKDLSARFSEASHKHKETLAKMEELKTKVELFENLSEKLQTFLETKTQALTEVDVPGKDVTELSQYMQESTSEFLEHKKHLEVLHSLLKEISSHGLPSDKALVLEKTNNLSKKFKEMEDTIKEKKEAVTSCQEQLDAFQVLVKSLKSWIKETTKKVPIVQPSFGAEDLGKSLEDTKKLQEKWSLKTPEIQKVNNSGISLCNLISAVTTPAKAIAAVKSGGAVLNGEGTATNTEEFWANKGLTSIKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKTATKWQQTPAPTDTEAVKTQVEQNKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEIDSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLSIDPNMLNTQRQQVQILLQEFATRKPQYEQLTAAGQGILSRPGEDPSLRGIVKEQLAAVTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSDKLSDLDNKLSSSLAVSTHPDAMNQQLETAQKMKQEIQQEKKQIKVAQALCEDLSALVKEEYLKAELSRQLEGILKSFKDVEQKAENHVQHLQSACASSHQFQQMSRDFQAWLDTKKEEQNKSHPISAKLDVLESLIKDHKDFSKTLTAQSHMYEKTIAEGENLLLKTQGSEKAALQLQLNTIKTNWDTFNKQVKERENKLKESLEKALKYKEQVETLWPWIDKCQNNLEEIKFCLDPAEGENSIAKLKSLQKEMDQHFGMVELLNNTANSLLSVCEIDKEVVTDENKSLIQKVDMVTEQLHSKKFCLENMTQKFKEFQEVSKESKRQLQCAKEQLDIHDSLGSQAYSNKYLTMLQTQQKSLQALKHQVDLAKRLAQDLVVEASDSKGTSDVLLQVETIAQEHSTLSQQVDEKCSFLETKLQGIGHFQNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKETIKAFLKKLEALMASNDNANKTCKMMLATEETSPDLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEESQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLEHDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSAEFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKLSKLSVQDYSTEGLWKQQSELRVLQEDILLRKQNVDQALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTWLDKVEVELLSYETQVLKGEEASQAQMRPKELKKEAKNNKALLDSLNEVSSALLELVPWRAREGLEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDIRLEQDQTSAQLQVQKTFTMEILRHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSPGEGFSIQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIARSGGTDKDISAKAVQDKLDQMVFIWENIHTLVEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLEDPGIDPSVVKQQQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGSRDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKHWITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEVIPQEIEEVKALIAEHQTFMEEMTRKQPDVDKVTKTYKRRAADPSSLQSHIPVLDKGRAGRKRFPASSLYPSGSQTQIETKNPRVNLLVSKWQQVWLLALERRRKLNDALDRLEELREFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAYKPITDADKIEDEVTRQVAKCKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRAKGRTNMELREKFILADGASQGMAAFRPRGRRSRPSSRGASPNRSTSVSSQAAQAASPQVPATTTPKILHPLTRNYGKPWLTNSKMSTPCKAAECSDFPVPSAEGTPIQGSKLRLPGYLSGKGFHSGEDSGLITTAAARVRTQFADSKKTPSRPGSRAGSKAGSRASSRRGSDASDFDISEIQSVCSDVETVPQTHRPTPRAGSRPSTAKPSKIPTPQRKSPASKLDKSSKR
"
sig_peptide 109..237
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
mat_peptide 238..15621
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/product="bullous pemphigoid antigen 1 isoform 1eA"
misc_feature 952..1227
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats; Region: SPEC; smart00150"
/db_xref="CDD:197544"
misc_feature 1231..1779
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature 1540..1557
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature <2635..4221
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="ATPase involved in DNA repair [DNA replication,
recombination, and repair]; Region: SbcC; COG0419"
/db_xref="CDD:30768"
misc_feature 3100..3102
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3652..6054
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Chromosome segregation ATPases [Cell division and
chromosome partitioning]; Region: Smc; COG1196"
/db_xref="CDD:31389"
misc_feature 4642..5331
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature 4774..4776
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 4780..4782
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 4996..5013
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 5005..5661
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature 5335..5352
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 5509..5511
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 6412..7077
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature 6739..6756
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 7417..8052
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature 7729..7746
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 7738..8373
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature 8050..8067
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 8059..8703
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature order(8377..8385,8389..8397)
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 8716..9363
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature 9040..9057
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 9058..9699
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature 9367..9384
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 9379..10026
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature 9694..9711
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 10030..10677
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature 10102..10104
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature order(10348..10350,10354..10368)
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 10363..11004
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature 10675..10692
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 11017..11670
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature 11089..11091
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 11338..11355
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 11347..12000
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature 11665..11682
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 11683..12327
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature order(11995..11997,12001..12015)
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 12007..12654
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature 12322..12339
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 12331..12981
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature order(12649..12660,12664..12669)
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 12658..13311
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature 12976..12993
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 13324..13962
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature 13630..13647
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 13639..14382
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Spectrin repeats, found in several proteins
involved in cytoskeletal structure; family members include
spectrin, alpha-actinin and dystrophin; the spectrin
repeat forms a three helix bundle with the second helix
interrupted by proline in some sequences; Region: SPEC;
cd00176"
/db_xref="CDD:29138"
misc_feature order(13957..13965,13978..13986)
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="linker region; other site"
/db_xref="CDD:29138"
misc_feature 14473..14661
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="EF-hand, calcium binding motif; A diverse
superfamily of calcium sensors and calcium signal
modulators; most examples in this alignment model have 2
active canonical EF hands. Ca2+ binding induces a
conformational change in the EF-hand motif, leading to...;
Region: EFh; cd00051"
/db_xref="CDD:28933"
misc_feature 14491..14658
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="EF-hand domain pair; Region: EF_hand_5; pfam13499"
/db_xref="CDD:205677"
misc_feature order(14500..14502,14506..14508,14512..14514,14533..14535,
14608..14610,14614..14616,14620..14622,14641..14643)
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Ca2+ binding site [ion binding]; other site"
/db_xref="CDD:28933"
misc_feature 14698..14934
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/note="Growth-Arrest-Specific Protein 2 Domain; Region:
GAS2; smart00243"
/db_xref="CDD:128539"
misc_feature 15439..15441
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 15448..15450
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
STS 6577..6677
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/standard_name="EST4G12"
/db_xref="UniSTS:263370"
variation 14430
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/replace="c"
/replace="t"
/db_xref="dbSNP:17292790"
variation 14651
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/replace="c"
/replace="t"
/db_xref="dbSNP:1049797"
STS 15560..15728
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/standard_name="D6S1122E"
/db_xref="UniSTS:21947"
STS 16180..16315
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/standard_name="D6S1159E"
/db_xref="UniSTS:26810"
STS 16349..16467
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
/standard_name="RH15996"
/db_xref="UniSTS:55081"
polyA_signal 16368..16373
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
polyA_site 16391
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
polyA_signal 16613..16618
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
polyA_site 16633
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
polyA_site 16642
/gene="DST"
/gene_synonym="BP240; BPA; BPAG1; CATX-15; CATX15;
D6S1101; DMH; DT; HSAN6; MACF2"
ORIGIN
aatattcagctgccacttttcaccgttagaagtagagctttttccagacctcctaccttttagtctactttgaaaggtgaaagaaagaacatcgtttcaggaataaaaatgcacagtagtagttatagttaccgtagcagtgattctgtgtttagtaacactaccagcactcgaaccagtcttgattcaaatgaaaatcttctcttggttcattgtggtccaacactgatcaactcttgcattagcttcggcagtgaatcctttgatggacacaggttagaaatgttgcaacagattgccaacagagttcagagggacagtgtcatctgtgaagacaaactgattcttgctggaaatgctcttcagtctgattctaaaagattagaatcaggagtgcagtttcagaatgaagcagaaattgctgggtatatacttgaatgtgagaaccttttacgccagcatgtaattgatgtacagattcttattgatggaaaatactaccaggcagatcaattggtacagagggttgcaaaactgcgtgacgaaattatggccttaaggaacgaatgttcttctgtgtacagcaaaggacgcatactgacaacagaacagacaaagctcatgatatcaggaatcactcaaagtttaaactcaggatttgcacagaccttacaccctagtctgacctcagggctgacccagagtttaacaccttccctaacctcttctagtatgacttctggcctgtcatcagggatgacttcccgcctgactccatctgtcactccagcttatacacctggtttcccatcaggattagttccaaatttcagttcaggagtagagccaaattcattgcaaactttgaagttgatgcagatccgaaaaccccttctaaagtcttctttgctggatcaaaatttaacagaagaagaaatcaatatgaaatttgttcaggatcttttgaattgggttgatgagatgcaggtacaactggaccgcactgagtggggctcagatttgccaagtgttgaaagccatttagaaaatcataaaaatgttcatagagctattgaagaatttgaatctagtctcaaagaagctaaaatcagtgagattcaaatgacagcacctcttaaactgacttatgcagaaaagttgcacagattagagagtcagtatgcaaaactcttgaatacatccaggaatcaagaacggcaccttgatacactccataattttgtaagtcgtgcgactaatgaacttatttggttgaatgaaaaagaagaggaggaagttgcttatgactggagtgagagaaacaccaacatagctaggaaaaaagattatcatgctgaattaatgagagaacttgatcaaaaggaagaaaatattaaatcagttcaggagatagcagagcagctacttctagaaaatcatccagcccggttaactattgaggcctacagagcggcaatgcagacgcagtggagctggatcttacagctctgccagtgtgtggagcagcacataaaggagaacacagcgtatttcgagtttttcaatgatgccaaagaagctactgattacttaaggaatctaaaagatgccattcagcggaagtacagctgtgatagatcaagcagcattcacaagctagaagaccttgttcaggaatcaatggaagagaaagaagaacttctgcagtacaaaagcactatagcaaacctaatgggaaaagcaaaaacaataattcaactgaagccaaggaattctgactgtccactcaaaacttctattccgatcaaagctatctgtgactacagacaaattgagataaccatttacaaagacgatgaatgtgttttggcgaataactctcatcgtgctaaatggaaggtcattagtcctactgggaatgaggctatggtcccatctgtgtgcttcaccgttcctccaccaaacaaagaagcggtggaccttgccaacagaattgagcaacagtatcagaatgtcctgactctttggcatgagtctcacataaacatgaagagtgtagtatcctggcattatctcatcaatgaaattgatagaattcgagctagcaatgtggcttcaataaagacaatgctacctggtgaacatcagcaagttctaagtaatctacaatctcgttttgaagattttctggaagatagccaggaatcccaagtcttttcaggctcagatataacacaactggaaaaggaggttaatgtatgtaagcagtattatcaagaacttcttaaatctgcagaaagagaggagcaagaggaatcagtttataatctctacatctctgaagttcgaaacattagacttcggttagagaactgtgaagatcggctgattagacagattcgaactcccctggaaagagatgatttgcatgaaagtgtgttcagaatcacagaacaggagaaactaaagaaagagctggaacgacttaaagatgatttgggaacaatcacaaataagtgtgaggagtttttcagtcaagcagcagcctcttcatcagtccctaccctacgatcagagcttaatgtggtccttcagaacatgaaccaagtctattctatgtcttccacttacatagataagttgaaaactgttaacttggtgttaaaaaacactcaagctgcagaagccctcgtaaaactctatgaaactaaactgtgtgaagaagaagcagttatagctgacaagaataatattgagaatctaataagtactttaaagcaatggagatctgaagtagatgaaaagagacaggtattccatgccttagaggatgagttgcagaaagctaaagccatcagtgatgaaatgtttaaaacgtataaagaacgggaccttgattttgactggcacaaagaaaaagcagatcaattagttgaaaggtggcaaaatgttcatgtgcagattgacaacaggttacgggacttagagggcattggcaaatcactgaagtactacagagacacttaccatcctttagatgattggatccagcaggttgaaactactcagagaaagattcaggaaaatcagcctgaaaatagtaaaaccctagccacacagttgaatcaacagaagatgctggtgtccgaaatagaaatgaaacagagcaaaatggacgagtgtcaaaaatatgcagaacagtactcagctacagtgaaggactatgaattacaaacaatgacctaccgggccatggtagattcacaacaaaaatctccagtgaaacgccgaagaatgcagagttcagcagatctcattattcaagagttcatggacctaaggactcgatatactgccctggtcactctcatgacacaatatattaaatttgctggtgattcattgaagaggctggaagaggaggagaagtcactggaagaagaaaagaaagaacatgttgaaaaagccaaagaattgcaaaaatgggtatcaaatatcagcaagacattgaaagatgcagagaaggctggaaaacctcccttctctaagcaaaagatttccagtgaggaaatatcaaccaagaaggaacaattatcggaagcacttcaaactatacagctttttttggcaaaacatggagacaaaatgacagatgaagaaagaaatgaattggaaaaacaagtgaaaactcttcaggaaagttataatttattattcagtgaatctctgaaacagctacaagaatcacaaacctcaggagatgtaaaggtagaggagaagattgtagcagagcgtcagcaggagtataaagagaaactccaagggatatgtgatcttcttacccaaactgaaaaccgcctaattggtcaccaagaagccttcatgattggagatggcacagttgagttaaagaaatatcagtccaagcaagaggaattacagaaagatatgcaaggaagtgcacaggcattggctgaagtagtgaaaaacacagagaacttcttaaaagagaatggtgaaaagctgtcacaggaagataaggctttgattgaacagaaacttaatgaagctaagataaagtgtgaacagcttaatttaaaagcagaacagtctaaaaaggagctggataaagttgtgacaacagcaatcaaggaagaaactgaaaaggtagcagcagtgaagcagctggaagagagcaaaaccaaaatagaaaaccttttggactggttgtcaaatgttgacaaagactcagaaagggcagggacaaaacacaaacaggtaatcgaacagaacgggacccattttcaagaaggtgatggcaagtcagcaattggagaagaggatgaagttaatggtaacctgttggagactgatgttgatgggcaagttggaaccactcaggagaatctgaatcagcaatatcagaaagttaaggcccaacacgagaagatcatctctcagcaccaagcagtgatcatagccactcagtctgcacaagtgttgcttgagaaacagggtcagtatctctctcctgaagaaaaagagaaactgcaaaagaacatgaaggaactgaaagtgcattatgaaactgcactggctgagtcagagaagaaaatgaagttaactcactctctgcaggaagaattagaaaagtttgatgctgactataccgagtttgagcactggctacagcagtcagaacaagaacttgaaaacctggaggcaggtgcagatgacatcaatggtttaatgaccaaattgaagaggcagaagagtttctcagaagacgttatttctcacaaaggtgacttgagatacatcacaatttctggaaacagagtgttggaagctgccaaatcttgcagcaagagagacggtggcaaggttgatacttctgcaacccacagagaagtgcagcgcaagttggatcatgctactgatcggttcaggtctctctactctaagtgcaatgttcttggaaataatcttaaagatctggt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//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:667 -> Molecular function: GO:0003779 [actin binding] evidence: IEA
GeneID:667 -> Molecular function: GO:0005178 [integrin binding] evidence: IPI
GeneID:667 -> Molecular function: GO:0005509 [calcium ion binding] evidence: IEA
GeneID:667 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:667 -> Molecular function: GO:0008022 [protein C-terminus binding] evidence: IPI
GeneID:667 -> Molecular function: GO:0042803 [protein homodimerization activity] evidence: IDA
GeneID:667 -> Molecular function: GO:0051010 [microtubule plus-end binding] evidence: IDA
GeneID:667 -> Biological process: GO:0000226 [microtubule cytoskeleton organization] evidence: IDA
GeneID:667 -> Biological process: GO:0007010 [cytoskeleton organization] evidence: IMP
GeneID:667 -> Biological process: GO:0007050 [cell cycle arrest] evidence: IEA
GeneID:667 -> Biological process: GO:0007155 [cell adhesion] evidence: IEA
GeneID:667 -> Biological process: GO:0007229 [integrin-mediated signaling pathway] evidence: NAS
GeneID:667 -> Biological process: GO:0007409 [axonogenesis] evidence: IEA
GeneID:667 -> Biological process: GO:0008090 [retrograde axon cargo transport] evidence: IEA
GeneID:667 -> Biological process: GO:0009611 [response to wounding] evidence: IDA
GeneID:667 -> Biological process: GO:0030011 [maintenance of cell polarity] evidence: IMP
GeneID:667 -> Biological process: GO:0030198 [extracellular matrix organization] evidence: TAS
GeneID:667 -> Biological process: GO:0031110 [regulation of microtubule polymerization or depolymerization] evidence: IEA
GeneID:667 -> Biological process: GO:0031122 [cytoplasmic microtubule organization] evidence: IEA
GeneID:667 -> Biological process: GO:0031581 [hemidesmosome assembly] evidence: IDA
GeneID:667 -> Biological process: GO:0045104 [intermediate filament cytoskeleton organization] evidence: IEP
GeneID:667 -> Biological process: GO:0045104 [intermediate filament cytoskeleton organization] evidence: ISS
GeneID:667 -> Biological process: GO:0045104 [intermediate filament cytoskeleton organization] evidence: NAS
GeneID:667 -> Biological process: GO:0048870 [cell motility] evidence: IMP
GeneID:667 -> Cellular component: GO:0005604 [basement membrane] evidence: TAS
GeneID:667 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:667 -> Cellular component: GO:0005635 [nuclear envelope] evidence: IEA
GeneID:667 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:667 -> Cellular component: GO:0005737 [cytoplasm] evidence: ISS
GeneID:667 -> Cellular component: GO:0005789 [endoplasmic reticulum membrane] evidence: IEA
GeneID:667 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:667 -> Cellular component: GO:0005882 [intermediate filament] evidence: IEA
GeneID:667 -> Cellular component: GO:0005938 [cell cortex] evidence: IEA
GeneID:667 -> Cellular component: GO:0009925 [basal plasma membrane] evidence: NAS
GeneID:667 -> Cellular component: GO:0015629 [actin cytoskeleton] evidence: IDA
GeneID:667 -> Cellular component: GO:0015629 [actin cytoskeleton] evidence: IEA
GeneID:667 -> Cellular component: GO:0015630 [microtubule cytoskeleton] evidence: IDA
GeneID:667 -> Cellular component: GO:0016021 [integral to membrane] evidence: IEA
GeneID:667 -> Cellular component: GO:0016023 [cytoplasmic membrane-bounded vesicle] evidence: IDA
GeneID:667 -> Cellular component: GO:0030018 [Z disc] evidence: IDA
GeneID:667 -> Cellular component: GO:0030018 [Z disc] evidence: IEA
GeneID:667 -> Cellular component: GO:0030056 [hemidesmosome] evidence: IDA
GeneID:667 -> Cellular component: GO:0030056 [hemidesmosome] evidence: TAS
GeneID:667 -> Cellular component: GO:0030424 [axon] evidence: IEA
GeneID:667 -> Cellular component: GO:0031252 [cell leading edge] evidence: IDA
GeneID:667 -> Cellular component: GO:0031673 [H zone] evidence: IEA
GeneID:667 -> Cellular component: GO:0033267 [axon part] evidence: IDA
GeneID:667 -> Cellular component: GO:0035371 [microtubule plus end] evidence: IDA
GeneID:667 -> Cellular component: GO:0045111 [intermediate filament cytoskeleton] evidence: IDA
GeneID:667 -> Cellular component: GO:0060053 [neurofilament cytoskeleton] evidence: IEA
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