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2024-04-18 20:14:11, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_015247 8730 bp mRNA linear PRI 24-JUN-2013
DEFINITION Homo sapiens cylindromatosis (turban tumor syndrome) (CYLD),
transcript variant 1, mRNA.
ACCESSION NM_015247 NM_016385
VERSION NM_015247.2 GI:109637772
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 8730)
AUTHORS Yang,W.L., Jin,G., Li,C.F., Jeong,Y.S., Moten,A., Xu,D., Feng,Z.,
Chen,W., Cai,Z., Darnay,B., Gu,W. and Lin,H.K.
TITLE Cycles of ubiquitination and deubiquitination critically regulate
growth factor-mediated activation of Akt signaling
JOURNAL Sci Signal 6 (257), RA3 (2013)
PUBMED 23300340
REMARK GeneRIF: CYLD is a molecular switch for cycles of ubiquitination
and deubiquitination that critically regulate growth
factor-mediated activation of Akt signaling.
Publication Status: Online-Only
REFERENCE 2 (bases 1 to 8730)
AUTHORS Ke,H., Augustine,C.K., Gandham,V.D., Jin,J.Y., Tyler,D.S.,
Akiyama,S.K., Hall,R.P. and Zhang,J.Y.
TITLE CYLD inhibits melanoma growth and progression through suppression
of the JNK/AP-1 and beta1-integrin signaling pathways
JOURNAL J. Invest. Dermatol. 133 (1), 221-229 (2013)
PUBMED 22832488
REMARK GeneRIF: these findings demonstrate that the JNK/activator protein
1 signaling pathway underlies the melanoma growth and metastasis
that are associated with CYLD loss of function.
REFERENCE 3 (bases 1 to 8730)
AUTHORS Nagy,N., Farkas,K., Kinyo,A., Nemeth,I.B., Kis,E., Varga,J.,
Bata-Csorgo,Z., Kemeny,L. and Szell,M.
TITLE A novel missense mutation of the CYLD gene identified in a
Hungarian family with Brooke-Spiegler syndrome
JOURNAL Exp. Dermatol. 21 (12), 967-969 (2012)
PUBMED 23171463
REMARK GeneRIF: We investigated a Hungarian Brooke Spiegler syndrome
pedigree with two affected members, demonstrating a novel missense
mutation (c.2613C>G; p.His871Gln) in exon 19 within the
ubiquitin-specific protease domain of the encoded protein.
REFERENCE 4 (bases 1 to 8730)
AUTHORS Chu,Y., Soberon,V., Glockner,L., Beyaert,R., Massoumi,R., van
Loo,G., Krappmann,D. and Schmidt-Supprian,M.
TITLE A20 and CYLD do not share significant overlapping functions during
B cell development and activation
JOURNAL J. Immunol. 189 (9), 4437-4443 (2012)
PUBMED 23002441
REMARK GeneRIF: Lack of both CYLD and A20 do not exacerbate the
developmental defects and hyperresponsive activity of A20-deficient
B cells.
REFERENCE 5 (bases 1 to 8730)
AUTHORS Gomez-Ferreria,M.A., Bashkurov,M., Mullin,M., Gingras,A.C. and
Pelletier,L.
TITLE CEP192 interacts physically and functionally with the
K63-deubiquitinase CYLD to promote mitotic spindle assembly
JOURNAL Cell Cycle 11 (19), 3555-3558 (2012)
PUBMED 22895009
REMARK GeneRIF: CEP192 promotes robust mitotic spindle assembly by
regulating K63-polyubiquitin-mediated signaling through CYLD.
REFERENCE 6 (bases 1 to 8730)
AUTHORS Bignell,G.R., Warren,W., Seal,S., Takahashi,M., Rapley,E.,
Barfoot,R., Green,H., Brown,C., Biggs,P.J., Lakhani,S.R., Jones,C.,
Hansen,J., Blair,E., Hofmann,B., Siebert,R., Turner,G., Evans,D.G.,
Schrander-Stumpel,C., Beemer,F.A., van Den Ouweland,A., Halley,D.,
Delpech,B., Cleveland,M.G., Leigh,I., Leisti,J. and Rasmussen,S.
TITLE Identification of the familial cylindromatosis tumour-suppressor
gene
JOURNAL Nat. Genet. 25 (2), 160-165 (2000)
PUBMED 10835629
REFERENCE 7 (bases 1 to 8730)
AUTHORS Fenske,C., Banerjee,P., Holden,C. and Carter,N.
TITLE Brooke-Spiegler syndrome locus assigned to 16q12-q13
JOURNAL J. Invest. Dermatol. 114 (5), 1057-1058 (2000)
PUBMED 10792569
REFERENCE 8 (bases 1 to 8730)
AUTHORS Thomson,S.A., Rasmussen,S.A., Zhang,J. and Wallace,M.R.
TITLE A new hereditary cylindromatosis family associated with CYLD1 on
chromosome 16
JOURNAL Hum. Genet. 105 (1-2), 171-173 (1999)
PUBMED 10480375
REFERENCE 9 (bases 1 to 8730)
AUTHORS Biggs,P.J., Chapman,P., Lakhani,S.R., Burn,J. and Stratton,M.R.
TITLE The cylindromatosis gene (cyld1) on chromosome 16q may be the only
tumour suppressor gene involved in the development of cylindromas
JOURNAL Oncogene 12 (6), 1375-1377 (1996)
PUBMED 8649842
REFERENCE 10 (bases 1 to 8730)
AUTHORS Biggs,P.J., Wooster,R., Ford,D., Chapman,P., Mangion,J., Quirk,Y.,
Easton,D.F., Burn,J. and Stratton,M.R.
TITLE Familial cylindromatosis (turban tumour syndrome) gene localised to
chromosome 16q12-q13: evidence for its role as a tumour suppressor
gene
JOURNAL Nat. Genet. 11 (4), 441-443 (1995)
PUBMED 7493027
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DA785459.1, AJ250014.1,
BX642061.1, DA157717.1, DA940312.1 and AL050166.1.
This sequence is a reference standard in the RefSeqGene project.
On Jun 23, 2006 this sequence version replaced gi:14165257.
Summary: This gene is encodes a cytoplasmic protein with three
cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains
that functions as a deubiquitinating enzyme. Mutations in this gene
have been associated with cylindromatosis, multiple familial
trichoepithelioma, and Brooke-Spiegler syndrome. Alternate
transcriptional splice variants, encoding different isoforms, have
been characterized. [provided by RefSeq, Jul 2008].
Transcript Variant: This variant (1) represents the longer
transcript and encodes the longer isoform (1).
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AJ250014.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
ERS025081, ERS025082 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: full length.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-24 DA785459.1 1-24
25-5253 AJ250014.1 1-5229
5254-5266 BX642061.1 146-158 c
5267-5395 AJ250014.1 5243-5371
5396-5786 DA157717.1 182-572
5787-6373 DA940312.1 9-595
6374-8730 AL050166.1 315-2671
FEATURES Location/Qualifiers
source 1..8730
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="16"
/map="16q12.1"
gene 1..8730
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/note="cylindromatosis (turban tumor syndrome)"
/db_xref="GeneID:1540"
/db_xref="HGNC:2584"
/db_xref="HPRD:05427"
/db_xref="MIM:605018"
exon 1..75
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 8
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373031484"
exon 76..155
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
exon 156..292
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 262
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:188438281"
exon 293..919
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 316..317
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="a"
/db_xref="dbSNP:67190903"
variation 325
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369755094"
misc_feature 392..394
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/note="upstream in-frame stop codon"
variation 396
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:190977024"
CDS 416..3286
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/EC_number="3.4.19.12"
/note="isoform 1 is encoded by transcript variant 1;
ubiquitin specific peptidase like 2; ubiquitin
thiolesterase CYLD; probable ubiquitin carboxyl-terminal
hydrolase CYLD; ubiquitin-specific-processing protease
CYLD; deubiquitinating enzyme CYLD; ubiquitin thioesterase
CYLD"
/codon_start=1
/product="ubiquitin carboxyl-terminal hydrolase CYLD
isoform 1"
/protein_id="NP_056062.1"
/db_xref="GI:14165258"
/db_xref="CCDS:CCDS45482.1"
/db_xref="GeneID:1540"
/db_xref="HGNC:2584"
/db_xref="HPRD:05427"
/db_xref="MIM:605018"
/translation="
MSSGLWSQEKVTSPYWEERIFYLLLQECSVTDKQTQKLLKVPKGSIGQYIQDRSVGHSRIPSAKGKKNQIGLKILEQPHAVLFVDEKDVVEINEKFTELLLAITNCEERFSLFKNRNRLSKGLQIDVGCPVKVQLRSGEEKFPGVVRFRGPLLAERTVSGIFFGVELLEEGRGQGFTDGVYQGKQLFQCDEDCGVFVALDKLELIEDDDTALESDYAGPGDTMQVELPPLEINSRVSLKVGETIESGTVIFCDVLPGKESLGYFVGVDMDNPIGNWDGRFDGVQLCSFACVESTILLHINDIIPALSESVTQERRPPKLAFMSRGVGDKGSSSHNKPKATGSTSDPGNRNRSELFYTLNGSSVDSQPQSKSKNTWYIDEVAEDPAKSLTEISTDFDRSSPPLQPPPVNSLTTENRFHSLPFSLTKMPNTNGSIGHSPLSLSAQSVMEELNTAPVQESPPLAMPPGNSHGLEVGSLAEVKENPPFYGVIRWIGQPPGLNEVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFASLQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYDDPDISAGKIKQFCKTCNTQVHLHPKRLNHKYNPVSLPKDLPDWDWRHGCIPCQNMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLYK
"
misc_feature 731..2194
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9NQC7.1);
Region: Interaction with TRIP"
misc_feature 794..1024
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/note="Cytoskeleton-associated proteins (CAPs) are
involved in the organisation of microtubules and
transportation of vesicles and organelles along the
cytoskeletal network; Region: CAP_GLY; smart01052"
/db_xref="CDD:198120"
misc_feature 1109..1324
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/note="CAP-Gly domain; Region: CAP_GLY; pfam01302"
/db_xref="CDD:201721"
misc_feature 1595..1822
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9NQC7.1);
Region: Interaction with TRAF2"
misc_feature 1610..1612
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1667..1669
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9NQC7.1); phosphorylation site"
misc_feature 1823..2077
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9NQC7.1);
Region: Interaction with IKBKG/NEMO"
misc_feature 1829..2035
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/note="Cytoskeleton-associated proteins (CAPs) are
involved in the organisation of microtubules and
transportation of vesicles and organelles along the
cytoskeletal network; Region: CAP_GLY; smart01052"
/db_xref="CDD:198120"
misc_feature 2444..3259
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/note="A subfamily of Peptidase C19. Peptidase C19
contains ubiquitinyl hydrolases. They are intracellular
peptidases that remove ubiquitin molecules from
polyubiquinated peptides by cleavage of isopeptide bonds.
They hydrolyze bonds involving the carboxyl...; Region:
Peptidase_C19N; cd02670"
/db_xref="CDD:73076"
misc_feature order(3026..3028,3083..3085)
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/note="active site"
/db_xref="CDD:73076"
variation 471
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:374624194"
variation 485
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368114885"
variation 502
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:34564491"
variation 541
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:202119806"
variation 573
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375455772"
variation 623
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369619557"
variation 628
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373198684"
variation 654
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201666656"
variation 659
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:376006417"
variation 793
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:369238843"
variation 916
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:373896011"
exon 920..1222
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 929
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201836260"
variation 933
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:12599808"
variation 949
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:377383082"
variation 953
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="g"
/replace="t"
/db_xref="dbSNP:370450747"
variation 984
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="t"
/db_xref="dbSNP:374118770"
variation 997
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201431389"
variation 1009
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:367580462"
variation 1033
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371338061"
variation 1050
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:375434282"
variation 1087
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="g"
/replace="t"
/db_xref="dbSNP:372885659"
variation 1090
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:184354524"
variation 1111
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:375486280"
variation 1174
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372020998"
exon 1223..1328
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 1306
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140033230"
variation 1313
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377066412"
variation 1324
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:202154956"
exon 1329..1337
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
exon 1338..1436
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 1347
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:200271412"
variation 1375
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:369147527"
variation 1398
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:372199798"
variation 1420
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:374929114"
exon 1437..1553
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 1456
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:369452792"
variation 1460
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373172148"
exon 1554..1933
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 1578
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:199606039"
variation 1581
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:200759332"
variation 1587
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:138976689"
variation 1604
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:149427272"
variation 1605
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370428449"
variation 1607
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="g"
/replace="t"
/db_xref="dbSNP:202120212"
variation 1624
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371382898"
variation 1640
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:375579250"
variation 1707
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200494719"
variation 1738
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="t"
/db_xref="dbSNP:368393884"
variation 1746
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:371683706"
variation 1771
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200886685"
variation 1775
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200451975"
variation 1780
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371867434"
variation 1888
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:75757530"
variation 1897
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369789110"
exon 1934..2099
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 1965
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:201523761"
exon 2100..2241
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 2140
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373031051"
exon 2242..2364
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 2335
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:182210792"
exon 2365..2456
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 2434
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373899187"
exon 2457..2523
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
exon 2524..2656
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 2560
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:200905032"
variation 2587
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:373971257"
variation 2655
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:121908389"
exon 2657..2765
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 2659
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370702435"
variation 2687
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:121908388"
variation 2734
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199912760"
exon 2766..2884
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 2801
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:374104988"
variation 2805
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199624138"
variation 2827
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:2066852"
variation 2849
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371330250"
exon 2885..3101
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 2953
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:376293566"
variation 2968
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:370020837"
variation 3004
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201868355"
variation 3013
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:200765362"
variation 3021
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:200154154"
variation 3034
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="g"
/replace="t"
/db_xref="dbSNP:373541485"
exon 3102..8713
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/inference="alignment:Splign:1.39.8"
variation 3221
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:121908390"
variation 3229
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199632232"
variation 3297
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373881703"
variation 3320
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="g"
/replace="t"
/db_xref="dbSNP:376027595"
variation 3333
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:116979331"
STS 3343..3632
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/standard_name="SHGC-60837"
/db_xref="UniSTS:67819"
variation 3425
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:148107725"
STS 3431..3619
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/standard_name="RH64884"
/db_xref="UniSTS:83726"
polyA_signal 3638..3643
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
polyA_site 3667
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
variation 3668
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:142580891"
variation 4065
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:190787930"
variation 4117
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:144877731"
variation 4123
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:3743781"
variation 4127
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:117537927"
variation 4208
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375222421"
variation 4261
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:369791294"
STS 4303..4444
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/standard_name="RH94254"
/db_xref="UniSTS:88351"
variation 4339
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="t"
/db_xref="dbSNP:147959249"
variation 4388
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:141088048"
variation 4408
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:114552144"
variation 4477
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:146935881"
variation 4528
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:150937990"
variation 4531
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:192470603"
variation 4627
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="g"
/replace="t"
/db_xref="dbSNP:140767609"
variation 4713
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150124371"
STS 4743..5443
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/standard_name="CYLD__4662"
/db_xref="UniSTS:471409"
variation 4861
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:184344245"
variation 4935
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:188778402"
variation 5085
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:138586985"
variation 5117
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:181246559"
variation 5208
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="t"
/db_xref="dbSNP:141752920"
variation 5270
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:145519346"
variation 5391..5393
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="gga"
/db_xref="dbSNP:75414200"
variation 5393
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="a"
/db_xref="dbSNP:111804189"
variation 5394
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:79868875"
variation 5406..5408
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="aaa"
/db_xref="dbSNP:74757288"
variation 5410
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:199826833"
variation 5448
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:138143910"
variation 5522
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:57638820"
variation 5557
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:185590115"
variation 5597..5599
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="ttc"
/db_xref="dbSNP:370824949"
variation 5621
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:9646285"
variation 5655
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:16948829"
variation 5668
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:189512578"
variation 5737
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368296872"
variation 5819
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="g"
/replace="t"
/db_xref="dbSNP:371051271"
STS 5844..6012
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/standard_name="RH48312"
/db_xref="UniSTS:65489"
variation 5892
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="t"
/db_xref="dbSNP:371917388"
variation 5901
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:181056407"
variation 5962
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:76888453"
variation 5996
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141928186"
polyA_signal 6056..6061
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
variation 6074..6075
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="tg"
/db_xref="dbSNP:375257369"
polyA_site 6077
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
variation 6356
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:144667145"
variation 6369
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:185943382"
variation 6398
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="t"
/db_xref="dbSNP:149875014"
variation 6421
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:374305356"
variation 6525
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:34088926"
variation 6538
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="g"
/replace="t"
/db_xref="dbSNP:375925980"
variation 6595
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:192317768"
variation 6709
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:183255879"
variation 6741
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:186163821"
variation 6755
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:111951225"
variation 6849
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:190533095"
variation 6879
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368698335"
variation 6883
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372708124"
variation 6900
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="c"
/db_xref="dbSNP:372370285"
variation 6965
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141888517"
variation 6966
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="g"
/replace="t"
/db_xref="dbSNP:374723746"
variation 6982
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:182950511"
variation 7025
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:16948836"
variation 7042
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:188392607"
variation 7159
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:192669779"
variation 7232
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:367816704"
variation 7241
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371569379"
variation 7366
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:183024011"
variation 7440
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376037772"
variation 7567
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="g"
/db_xref="dbSNP:187441896"
variation 7847
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:17314948"
variation 7853
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:113748745"
variation 7862
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373507820"
variation 7901..7902
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="g"
/db_xref="dbSNP:34262697"
variation 7995
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:192535029"
variation 8126
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150641352"
variation 8171
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="a"
/replace="t"
/db_xref="dbSNP:184571054"
variation 8174..8175
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace=""
/replace="at"
/db_xref="dbSNP:143814807"
variation 8335
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:187446083"
variation 8523
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:192242759"
variation 8558
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/replace="c"
/replace="t"
/db_xref="dbSNP:140875917"
STS 8565..8668
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
/standard_name="SGC32374"
/db_xref="UniSTS:28941"
polyA_signal 8690..8695
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
polyA_site 8713
/gene="CYLD"
/gene_synonym="BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1;
SBS; TEM; USPL2"
ORIGIN
gtgcggttcggaggcggggcaggtgggggcgggcccaggtagcaggtttggctgcgcgggggccgcgcgtcggagtttccccctttctagggtgaggatggttctacacagccacccggagttccttagttgaaaggtgcgccctgctgtgacagaatgtggtaattgtaatctttaacattttcatgtaaaacatatttcctgatcatctttccattgtcttcatggaaaattgataaatatttgtgccttccaactctcgtcttggttgaatgacttcatcttaatacaacatggacaccacgttgctgaaaacatgctttgggactgccactgaatttatcttttgcggttttatgacaaagttattagtagtttcccttttttgaattagtattttgaagttaatatcacaatgagttcaggcttatggagccaagaaaaagtcacttcaccctactgggaagagcggattttttacttgcttcttcaagaatgcagcgttacagacaaacaaacacaaaagctccttaaagtaccgaagggaagtataggacagtatattcaagatcgttctgtggggcattcaaggattccttctgcaaaaggcaagaaaaatcagattggattaaaaattctagagcaacctcatgcagttctctttgttgatgaaaaggatgttgtagagataaatgaaaagttcacagagttacttttggcaattaccaattgtgaggagaggttcagcctgtttaaaaacagaaacagactaagtaaaggcctccaaatagacgtgggctgtcctgtgaaagtacagctgagatctggggaagaaaaatttcctggagttgtacgcttcagaggacccctgttagcagagaggacagtctccggaatattctttggagttgaattgctggaagaaggtcgtggtcaaggtttcactgacggggtgtaccaagggaaacagctttttcagtgtgatgaagattgtggcgtgtttgttgcattggacaagctagaactcatagaagatgatgacactgcattggaaagtgattacgcaggtcctggggacacaatgcaggtcgaacttcctcctttggaaataaactccagagtttctttgaaggttggagaaacaatagaatctggaacagttatattctgtgatgttttgccaggaaaagaaagcttaggatattttgttggtgtggacatggataaccctattggcaactgggatggaagatttgatggagtgcagctttgtagttttgcgtgtgttgaaagtacaattctattgcacatcaatgatatcatcccagctttatcagagagtgtgacgcaggaaaggaggcctcccaaacttgcctttatgtcaagaggtgttggggacaaaggttcatccagtcataataaaccaaaggctacaggatctacctcagaccctggaaatagaaacagatctgaattattttataccttaaatgggtcttctgttgactcacaaccacaatccaaatcaaaaaatacatggtacattgatgaagttgcagaagaccctgcaaaatctcttacagagatatctacagactttgaccgttcttcaccaccactccagcctcctcctgtgaactcactgaccaccgagaacagattccactctttaccattcagtctcaccaagatgcccaataccaatggaagtattggccacagtccactttctctgtcagcccagtctgtaatggaagagctaaacactgcacccgtccaagagagtccacccttggccatgcctcctgggaactcacatggtctagaagtgggctcattggctgaagttaaggagaaccctcctttctatggggtaatccgttggatcggtcagccaccaggactgaatgaagtgctcgctggactggaactggaagatgagtgtgcaggctgtacggatggaaccttcagaggcactcggtatttcacctgtgccctgaagaaggcgctgtttgtgaaactgaagagctgcaggcctgactctaggtttgcatcattgcagccggtttccaatcagattgagcgctgtaactctttagcatttggaggctacttaagtgaagtagtagaagaaaatactccaccaaaaatggaaaaagaaggcttggagataatgattgggaagaagaaaggcatccagggtcattacaattcttgttacttagactcaaccttattctgcttatttgcttttagttctgttctggacactgtgttacttagacccaaagaaaagaacgatgtagaatattatagtgaaacccaagagctactgaggacagaaattgttaatcctctgagaatatatggatatgtgtgtgccacaaaaattatgaaactgaggaaaatacttgaaaaggtggaggctgcatcaggatttacctctgaagaaaaagatcctgaggaattcttgaatattctgtttcatcatattttaagggtagaacctttgctaaaaataagatcagcaggtcaaaaggtacaagattgttacttctatcaaatttttatggaaaaaaatgagaaagttggcgttcccacaattcagcagttgttagaatggtcttttatcaacagtaacctgaaatttgcagaggcaccatcatgtctgattattcagatgcctcgatttggaaaagactttaaactatttaaaaaaatttttccttctctggaattaaatataacagatttacttgaagacactcccagacagtgccggatatgtggagggcttgcaatgtatgagtgtagagaatgctacgacgatccggacatctcagctggaaaaatcaagcagttttgtaaaacctgcaacactcaagtccaccttcatccgaagaggctgaatcataaatataacccagtgtcacttcccaaagacttacccgactgggactggagacacggctgcatcccttgccagaatatggagttatttgctgttctctgcatagaaacaagccactatgttgcttttgtgaagtatgggaaggacgattctgcctggctcttctttgacagcatggccgatcgggatggtggtcagaatggcttcaacattcctcaagtcaccccatgcccagaagtaggagagtacttgaagatgtctctggaagacctgcattccttggactccaggagaatccaaggctgtgcacgaagactgctttgtgatgcatatatgtgcatgtaccagagtccaacaatgagtttgtacaaataactggggtcatcgggaaaggcaaagaaactgaaggcagagtcctaacgttgcatcttattcgagctggcagttctgttcacgtccattgccggcaatggatgtctttgtggtgatgatccttcagaaaaggatgcctctgtttaaaaacaaattgcttttgtgtccctgaagtatttaataagaagcattttgcactctagaaagtatgtttgtgttggttttttaagaagtctaaatgaagttattaatacctgaagctttaagttaagtgcattgatcatatgatatttttggaagcatacaattttaattgtggaagtttaaagcctcttttagtccattgagaatgtaaataaatgtgtcttctttatggaccaaggatatgaaatcatttttcttttgtagctaacggttgccttgaggaagaaataatttggttttattaagagtctactctcaatccagttattagagatgtactgagtttgatttgttaatcctttctatatactgctgatcttgcatgtctacaatctgctcagtttttctgtgtttctgcaatagtggtcagaaaaatacttaaattcccttaatggtgttgttttctatttgttctggttttgagataaatgagtgattctgtccccaaatgtccatttttgaagtgattttcctggaggattagggtatttagcagttgaagctcttcattcatagtagttactgtcagctaacaggttttttaaggcttttaactattaatattttatggaatggggcaaagtaaattgatgaaagaattggagtgataatagtcctttacaaacatacagtccataagaaaatgaatttggcatatagaattattacaatttcctgggagagatggatatttaaacctctattattttagacaagactgtctagaacttaagtttgatctgtcagccagtactcccattaaattcagtgtagtttcacttgatagaatcagatatgttatcgaaatgttagcagcagcttcatcctccttctgattaaagtaagtagaaatgggatgttttgtttaataacagccatagtgtgtgtttagaccacagcggatgttgtagaccaggaccatagatgatacatgtcagtgctgtggaatgtgcattctctgagtgttgttttgtggtatcattgtctttcctgaatgactttctaactgtgcagaaaggcagaaaagtcatcatatgtatatgtcatatgactttataaaatatttaatgtgacaaaaagtggaaagaatctttacaaaccctgcaattacttttttaaaggcacttttactctttggttttatcattccattttgctaatatttactagctttataaattacagtaaggtacaaaaactcatcttgtaatattttcatttttgaagtgaaaaagtacatatattttgcacaaggttttatactgctaagtgcttggttggggtggtgagatgatgattagatcaggggtgaggctgagagactctgggtttagggctagccctgcctccatctcccttgggtaaaatgaagggtgtggggtaaaagatgcataaggccttttctagctctgacagcctagaagtccaatcaccctgtaataaatatgtgttgaatgaagaaatgggtgaatgagcttgtcaatgtgattttaaaaaattgactacctggaggaatgattaggaatctaaatgaagccagccctcggtatctgcaggtttctcatccatggattcaaccaactgcaaatggaaaatacgattttttttaaaaaaaggatggttacatccgtattgaacatgtacagacttttttcttgtcattattctctgaacaatacaagaactctttatgtagcatttacatttattaggtattataagtaatctagagattatttaattaaaatatacaggaggatgtgtgtcagttatatgcaaattctgtaccattttgtatcagggaattgagcatcttcagatgttggtatctgcagggatcctggaaccaaacccctgcagatactaagggctgacgatctaggtaagactggatttaacagttggaaaaaaaaaaaaaaaaggagagagaagacagttcctttcctgtagaaattaaaacaaaatacaaattgaggaagctctgctacccaggctgtcatggtagagaacttgaagaagacctgtttggatggacacctggtttcaaaagtcaggtgtggagactgttaaatgggagggcctcatccataaatgatttctggcaacgtcttcttcaggtggagcttgacgtctttttaatgttacttggggagggagtgctcattaagggatgccagggccagctctggtggttcctggggaggctgcgtccttccctgcttctgcatgtcatgaggcagcaggaaggtttcccctgcacctgtctgtcctggctccctctgggtagccccctactgttctgtgcttcagcacagcctggtttgtcaagaggcacatagttggggctgggctgcatggcacaggggcttatgtgcctgctggttatttaattttcagccttaagttttctttaatattttcctgttggctatttaaaggttttggttatcttttattccttatctacaatcaagatgacaatgtaattgaattatcttatttataacacggttcgtgattcatgattcatgattacaagtagaaaatatgtcatgttcctcacctccaaataaatatgtgtgtgtctgtgtgtgtgtatatatgtatgtggcggagagggagagagtggggaaggagagcagtgttatcatacatagagaggctaaatgtgtcccatccctcactgtcagctttataaaggagtttgactccatccacagaagaatgttttataagactaggaaaacacgttgaaaactaggataaacagcaacaaaaatcaactaaatatgttgttactgttgctaaggattttctccttagaataatttaggatttttaaaaatttctgtttgccaaatgctgtagataaatggccagattcttcctatccctaggattcctttattattttttttcacagattttgagaacaagggggagagatagtatggaagattaagattccattaatcttatagaactgtgttgtcacccaaattcctgcttgtttgaacatggcatcttcatagattcaggattcactaccctctatagctggatcttgaaaattatctggccagataattttgcatctgcttggatgattgtagactgagatgtgagtggaggataaagtattagacttttgctgagtaactgccaaccaagaagtatttatcggacacttactaggtgcctaggattgtatcagagggaatatgaaatgtgtccctgccctacctagttttaacgacagaatatctattaaaggctacttagctgaagggtaagggtgacaggtctaggggaagctttgggaggtggtgtgctgtgacagaaaaagtggcagagtagggacgagagacctgcattctagccctgtttctgtcacttgctctgtacacttagacaacagcttgacctcttgagctttagtttcctcctctgcataatgagagggttagactactgaattgtatgggaaaaaaatacaaattcctgggtcctaggccatgcctgctgaatccgactgttcaggaagaggcctaggaaatctgtgagggaatccccaggggaatctcgtgaccagccaggtgtgaaatctgctaactggaagatctcaaagcttccttcactttttgtgattttgtggtcatgtaacgttactgtattattctacgtaaatgtgggtacttggatgtttatcatactgtttctctgtgtttacatactaatttgtgtaagaaatgcattttagtctgtgtacctcaacctgctgtttgtttcctagaggtgttagtagtctttaaatacaagtaagacttaagaggatatttgatgttatttacctggatattttcttccccttttatttatttagaggaaattgagattctaggagccaaaaaaatgaaaacaaaattctaaggcaaagttaaagaaaaaaattacattatttcttaccatttgctactttataatgaaaatttaaaaattatatgggaagatttttctctgggataacaaatccttgtcataaagtaagaggtctttttaaagtaggtaggctataaggcctgtaatttaaaataatactcctttctctagggtttggtgcaattctccattaatgaagataacatttgaattccccaaagcaggtgaggagtcggggaggagaaagcgatgttaaaatgaaaactcactgcaaaagaggaggcagaggaagaaggaatgtaaaccccttaaagcagatgtgtgtggggccttatgaagaccaggattctgcgggtgtcaggggattgcccctcttgacagagactagggttttagactgaggcttcctgcagggtgttcgcattgcccttctccgttccccttcagacctttctggggagaagaggtgggaggaggggagaaagactgttcatcttattctgaatcctggagcagctgaaggttttctcttgagtcaggatgcagtggtaatgcattaaccagcaagtgtggccaaggataatgaaaaagtgggaaaggaaggtcctcctcctccctgattgtagcatccagcagtctctgtagccaggttactcaagaaccacatttgatttcctggccctttgccttggcagtgatggcatttttatttcactgtgttttaaagtcttcatttatttttataacatgggttagggagaagggccacaaatggagggattgtcctttcaagcaccacagcttcagataaaattagtactttcaaatattgtccactttaacttaaaaaattctagagggattatattggagactcaactgcccttggttttagtttataaaatggcctagtactgtggaattttaattttagaaagtcttagcatcagatcataaacattcattaaaagaactcacatcccatctgaaacttcccaggggagttgggattcttagtagattggtagaaaggggctcattttctactgcatttcccatttttggtatcttgttcagcatgttttatttttatttcttgtctgcagaacatcctatatttatgagaacattctttaagaagaccaccacatagaataccccttcctatcagctcgctctgatttagccttaattttgttaaattttttagagatgaatgaagtgctgctgtggaaagaaatgtacatatactatttctgtatcattaaaattacatttttatggttcaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:1540 -> Molecular function: GO:0004221 [ubiquitin thiolesterase activity] evidence: IEA
GeneID:1540 -> Molecular function: GO:0004843 [ubiquitin-specific protease activity] evidence: IDA
GeneID:1540 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:1540 -> Molecular function: GO:0008270 [zinc ion binding] evidence: IDA
GeneID:1540 -> Molecular function: GO:0019901 [protein kinase binding] evidence: IPI
GeneID:1540 -> Molecular function: GO:0070064 [proline-rich region binding] evidence: IPI
GeneID:1540 -> Biological process: GO:0006511 [ubiquitin-dependent protein catabolic process] evidence: IEA
GeneID:1540 -> Biological process: GO:0006917 [induction of apoptosis] evidence: IDA
GeneID:1540 -> Biological process: GO:0007049 [cell cycle] evidence: IEA
GeneID:1540 -> Biological process: GO:0007346 [regulation of mitotic cell cycle] evidence: IMP
GeneID:1540 -> Biological process: GO:0016055 [Wnt receptor signaling pathway] evidence: IEA
GeneID:1540 -> Biological process: GO:0032088 [negative regulation of NF-kappaB transcription factor activity] evidence: IDA
GeneID:1540 -> Biological process: GO:0032480 [negative regulation of type I interferon production] evidence: TAS
GeneID:1540 -> Biological process: GO:0035872 [nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway] evidence: TAS
GeneID:1540 -> Biological process: GO:0042347 [negative regulation of NF-kappaB import into nucleus] evidence: IDA
GeneID:1540 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
GeneID:1540 -> Biological process: GO:0070423 [nucleotide-binding oligomerization domain containing signaling pathway] evidence: TAS
GeneID:1540 -> Biological process: GO:0070507 [regulation of microtubule cytoskeleton organization] evidence: IMP
GeneID:1540 -> Biological process: GO:0070536 [protein K63-linked deubiquitination] evidence: IDA
GeneID:1540 -> Biological process: GO:0090090 [negative regulation of canonical Wnt receptor signaling pathway] evidence: IMP
GeneID:1540 -> Biological process: GO:2001238 [positive regulation of extrinsic apoptotic signaling pathway] evidence: IMP
GeneID:1540 -> Cellular component: GO:0005829 [cytosol] evidence: IDA
GeneID:1540 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:1540 -> Cellular component: GO:0005881 [cytoplasmic microtubule] evidence: IDA
GeneID:1540 -> Cellular component: GO:0030496 [midbody] evidence: IDA
GeneID:1540 -> Cellular component: GO:0031234 [extrinsic to internal side of plasma membrane] evidence: IDA
GeneID:1540 -> Cellular component: GO:0048471 [perinuclear region of cytoplasm] evidence: IEA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_056062 -> EC 3.4.19.12
by
@meso_cacase at
DBCLS
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