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2024-04-18 22:03:18, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_015192 7103 bp mRNA linear PRI 07-JUL-2013
DEFINITION Homo sapiens phospholipase C, beta 1 (phosphoinositide-specific)
(PLCB1), transcript variant 1, mRNA.
ACCESSION NM_015192
VERSION NM_015192.3 GI:459215047
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7103)
AUTHORS Liu,M., Ingle,J.N., Fridley,B.L., Buzdar,A.U., Robson,M.E.,
Kubo,M., Wang,L., Batzler,A., Jenkins,G.D., Pietrzak,T.L.,
Carlson,E.E., Goetz,M.P., Northfelt,D.W., Perez,E.A.,
Williard,C.V., Schaid,D.J., Nakamura,Y. and Weinshilboum,R.M.
TITLE TSPYL5 SNPs: association with plasma estradiol concentrations and
aromatase expression
JOURNAL Mol. Endocrinol. 27 (4), 657-670 (2013)
PUBMED 23518928
REFERENCE 2 (bases 1 to 7103)
AUTHORS Jia WH, Zhang B, Matsuo K, Shin A, Xiang YB, Jee SH, Kim DH, Ren Z,
Cai Q, Long J, Shi J, Wen W, Yang G, Delahanty RJ, Ji BT, Pan ZZ,
Matsuda F, Gao YT, Oh JH, Ahn YO, Park EJ, Li HL, Park JW, Jo J,
Jeong JY, Hosono S, Casey G, Peters U, Shu XO, Zeng YX and Zheng W.
CONSRTM Colon Cancer Family Registry (CCFR); Genetics and Epidemiology of
Colorectal Cancer Consortium (GECCO)
TITLE Genome-wide association analyses in East Asians identify new
susceptibility loci for colorectal cancer
JOURNAL Nat. Genet. 45 (2), 191-196 (2013)
PUBMED 23263487
REFERENCE 3 (bases 1 to 7103)
AUTHORS Adjobo-Hermans,M.J., Crosby,K.C., Putyrski,M., Bhageloe,A., van
Weeren,L., Schultz,C., Goedhart,J. and Gadella,T.W. Jr.
TITLE PLCbeta isoforms differ in their subcellular location and their
CT-domain dependent interaction with Galphaq
JOURNAL Cell. Signal. 25 (1), 255-263 (2013)
PUBMED 23006664
REMARK GeneRIF: PLCbeta1 is enriched at the plasma membrane.
REFERENCE 4 (bases 1 to 7103)
AUTHORS Philip,F., Guo,Y., Aisiku,O. and Scarlata,S.
TITLE Phospholipase Cbeta1 is linked to RNA interference of specific
genes through translin-associated factor X
JOURNAL FASEB J. 26 (12), 4903-4913 (2012)
PUBMED 22889834
REMARK GeneRIF: Data show a novel role of phospholipase Cbeta1 (PLCbeta1)
in gene regulation through translin-associated factor X (TRAX)
association.
REFERENCE 5 (bases 1 to 7103)
AUTHORS Poduri,A., Chopra,S.S., Neilan,E.G., Elhosary,P.C., Kurian,M.A.,
Meyer,E., Barry,B.J., Khwaja,O.S., Salih,M.A., Stodberg,T.,
Scheffer,I.E., Maher,E.R., Sahin,M., Wu,B.L., Berry,G.T.,
Walsh,C.A., Picker,J. and Kothare,S.V.
TITLE Homozygous PLCB1 deletion associated with malignant migrating
partial seizures in infancy
JOURNAL Epilepsia 53 (8), E146-E150 (2012)
PUBMED 22690784
REMARK GeneRIF: case report - homozygous deletion associated with
malignant migrating partial seizures in infancy
REFERENCE 6 (bases 1 to 7103)
AUTHORS Hwang,S.C., Park,K.H., Ha,M.J., Noh,I.S., Park,T.B. and Lee,Y.H.
TITLE Distribution of phospholipase C isozymes in normal human lung
tissue and their immunohistochemical localization
JOURNAL J. Korean Med. Sci. 11 (4), 305-313 (1996)
PUBMED 8878798
REFERENCE 7 (bases 1 to 7103)
AUTHORS Zini,N., Sabatelli,P., Faenza,I., Ognibene,A. and Maraldi,N.M.
TITLE Interleukin-1 alpha induces variations of the intranuclear amount
of phosphatidylinositol 4,5-bisphosphate and phospholipase C beta 1
in human osteosarcoma Saos-2 cells
JOURNAL Histochem. J. 28 (7), 495-504 (1996)
PUBMED 8872139
REFERENCE 8 (bases 1 to 7103)
AUTHORS Zauli,G., Previati,M., Caramelli,E., Bassini,A., Falcieri,E.,
Gibellini,D., Bertolaso,L., Bosco,D., Robuffo,I. and Capitani,S.
TITLE Exogenous human immunodeficiency virus type-1 Tat protein
selectively stimulates a phosphatidylinositol-specific
phospholipase C nuclear pathway in the Jurkat T cell line
JOURNAL Eur. J. Immunol. 25 (9), 2695-2700 (1995)
PUBMED 7589147
REFERENCE 9 (bases 1 to 7103)
AUTHORS Berstein,G., Blank,J.L., Jhon,D.Y., Exton,J.H., Rhee,S.G. and
Ross,E.M.
TITLE Phospholipase C-beta 1 is a GTPase-activating protein for Gq/11,
its physiologic regulator
JOURNAL Cell 70 (3), 411-418 (1992)
PUBMED 1322796
REFERENCE 10 (bases 1 to 7103)
AUTHORS Banno,Y., Yada,Y. and Nozawa,Y.
TITLE Purification and characterization of membrane-bound phospholipase C
specific for phosphoinositides from human platelets
JOURNAL J. Biol. Chem. 263 (23), 11459-11465 (1988)
PUBMED 2841328
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AB011153.3, AY004175.1,
AL049593.10 and BQ184058.1.
On Mar 5, 2013 this sequence version replaced gi:33356545.
Summary: The protein encoded by this gene catalyzes the formation
of inositol 1,4,5-trisphosphate and diacylglycerol from
phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium
as a cofactor and plays an important role in the intracellular
transduction of many extracellular signals. This gene is activated
by two G-protein alpha subunits, alpha-q and alpha-11. Two
transcript variants encoding different isoforms have been found for
this gene. [provided by RefSeq, Jul 2008].
Transcript Variant: This variant (1) encodes the longer isoform
(a).
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AB011153.3, BC069420.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025082, ERS025084 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-3374 AB011153.3 1-3374
3375-4038 AY004175.1 2973-3636
4039-5718 AB011153.3 4039-5718
5719-5719 AL049593.10 36391-36391
5720-6548 AB011153.3 5720-6548
6549-7103 BQ184058.1 1-555 c
FEATURES Location/Qualifiers
source 1..7103
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="20"
/map="20p12"
gene 1..7103
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/note="phospholipase C, beta 1
(phosphoinositide-specific)"
/db_xref="GeneID:23236"
/db_xref="HGNC:15917"
/db_xref="HPRD:06177"
/db_xref="MIM:607120"
exon 1..486
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 218
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="c"
/db_xref="dbSNP:139962835"
variation 356
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:372298655"
variation 368
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:374950042"
misc_feature 379..381
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/note="upstream in-frame stop codon"
CDS 388..4038
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/EC_number="3.1.4.11"
/note="isoform a is encoded by transcript variant 1;
PLC-beta-1; triphosphoinositide phosphodiesterase;
phosphoinositidase C; monophosphatidylinositol
phosphodiesterase;
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate;
inositoltrisphosphohydrolase; phospholipase C-I;
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
beta-1"
/codon_start=1
/product="1-phosphatidylinositol 4,5-bisphosphate
phosphodiesterase beta-1 isoform a"
/protein_id="NP_056007.1"
/db_xref="GI:12083581"
/db_xref="CCDS:CCDS13102.1"
/db_xref="GeneID:23236"
/db_xref="HGNC:15917"
/db_xref="HPRD:06177"
/db_xref="MIM:607120"
/translation="
MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKETELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKEFDTPL
"
misc_feature 436..798
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/note="Phospholipase C (PLC) pleckstrin homology (PH)
domain; Region: PH_PLC; cd01248"
/db_xref="CDD:176324"
misc_feature order(457..480,502..522,538..558,571..585,598..612,
691..711,733..750,763..798)
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/note="core domain; other site"
/db_xref="CDD:176324"
misc_feature order(475..477,496..498,508..510,556..558)
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/note="inositol phosphate binding site [chemical binding];
other site"
/db_xref="CDD:176324"
misc_feature 1057..1332
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/note="Phosphoinositide-specific phospholipase C,
efhand-like; Region: efhand_like; pfam09279"
/db_xref="CDD:150071"
misc_feature 1333..>1779
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/note="Catalytic domain of metazoan
phosphoinositide-specific phospholipase C-beta; Region:
PI-PLCc_beta; cd08591"
/db_xref="CDD:176533"
misc_feature order(1378..1383,1468..1470,1474..1476,1519..1521,
1621..1623)
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/note="putative active site [active]"
/db_xref="CDD:176533"
misc_feature order(1378..1380,1519..1521)
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/note="catalytic site [active]"
/db_xref="CDD:176533"
misc_feature order(1381..1383,1468..1470,1474..1476,1621..1623)
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/note="Ca binding site [ion binding]; other site"
/db_xref="CDD:176533"
misc_feature <2005..2316
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/note="Catalytic domain of phosphoinositide-specific
phospholipase C-like phosphodiesterases superfamily;
Region: PI-PLCc_GDPD_SF; cl14615"
/db_xref="CDD:213131"
misc_feature 2416..2775
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/note="C2 domain present in Phosphoinositide-specific
phospholipases C (PLC); Region: C2_PLC_like; cd00275"
/db_xref="CDD:175974"
misc_feature order(2467..2469,2545..2547,2638..2640,2644..2646,
2650..2652,2656..2658)
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/note="Ca2+ binding pocket [ion binding]; other site"
/db_xref="CDD:175974"
misc_feature 3046..3048
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:01498"
misc_feature 3046..3048
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:01501"
misc_feature 3097..3204
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/note="Protein of unknown function (DUF1154); Region:
DUF1154; pfam06631"
/db_xref="CDD:148313"
misc_feature 3331..3333
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3331..3333
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:03479"
misc_feature 3457..3888
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/note="PLC-beta C terminal; Region: PLC-beta_C; pfam08703"
/db_xref="CDD:204032"
variation 415
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="g"
/replace="t"
/db_xref="dbSNP:150241349"
STS 452..1384
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/standard_name="Plcb1"
/db_xref="UniSTS:507150"
exon 487..564
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 489
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:16994453"
variation 493
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:377750225"
variation 501
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:146304198"
variation 504
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:371499786"
variation 508
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:191106606"
variation 516
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:374402412"
variation 525
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:368510730"
exon 565..633
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
exon 634..771
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 670
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:199888561"
variation 672
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:138183168"
variation 673
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:200016726"
variation 674
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:375710411"
variation 675
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="g"
/replace="t"
/db_xref="dbSNP:200521017"
variation 718
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:373051695"
exon 772..851
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 793
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="t"
/db_xref="dbSNP:201510657"
variation 796
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:369124253"
variation 819
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:142874818"
variation 837
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:373476629"
variation 843
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:200598979"
variation 845
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="t"
/db_xref="dbSNP:45496299"
variation 851
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:148738915"
exon 852..905
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 873
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:202085165"
variation 889
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:142186851"
exon 906..981
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 962
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="g"
/replace="t"
/db_xref="dbSNP:78758453"
variation 969
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:150770296"
exon 982..1082
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 1014
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:151006778"
variation 1024
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:200713241"
variation 1026
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="c"
/db_xref="dbSNP:140899287"
variation 1047
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:184317533"
variation 1077
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:145276029"
exon 1083..1249
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 1101
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="c"
/db_xref="dbSNP:147567110"
variation 1111
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:200567140"
variation 1114
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:372097607"
variation 1115
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="t"
/db_xref="dbSNP:13037181"
variation 1116
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="g"
/replace="t"
/db_xref="dbSNP:13041270"
variation 1125
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:375123870"
variation 1184
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:369226956"
variation 1239
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:147648227"
exon 1250..1396
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 1262
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:370605921"
variation 1266
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:141935046"
variation 1276
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:149661663"
variation 1299
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:374061975"
variation 1300
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:370525961"
variation 1306
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:373633394"
variation 1311
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:6056003"
variation 1312
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:368967370"
variation 1329
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:182563538"
variation 1362
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:372723242"
variation 1377
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:375950955"
exon 1397..1554
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 1471
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:199900846"
variation 1514
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:201807011"
exon 1555..1637
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 1575
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:202109404"
variation 1617
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:148848282"
exon 1638..1722
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 1662
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:143366963"
exon 1723..1900
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 1802
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="c"
/db_xref="dbSNP:368448785"
variation 1803
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="g"
/replace="t"
/db_xref="dbSNP:201789409"
variation 1820
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="g"
/replace="t"
/db_xref="dbSNP:146833633"
variation 1821
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="g"
/db_xref="dbSNP:13042785"
variation 1833
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:372481162"
variation 1852
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="c"
/db_xref="dbSNP:13043353"
variation 1856
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:45608240"
variation 1857
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="c"
/db_xref="dbSNP:13042803"
variation 1878
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:145869401"
variation 1889
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="g"
/db_xref="dbSNP:200375635"
variation 1899
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:374258684"
exon 1901..1968
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 1913
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:150686631"
variation 1914
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:141857911"
variation 1926
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:199565459"
variation 1932
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:201832361"
variation 1938
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="g"
/replace="t"
/db_xref="dbSNP:150189968"
variation 1946
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:367767018"
variation 1960
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:138851178"
exon 1969..2065
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 2004
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="c"
/db_xref="dbSNP:149364174"
variation 2031
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:147407762"
exon 2066..2150
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 2139
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="g"
/db_xref="dbSNP:370361540"
variation 2148
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:143755415"
exon 2151..2275
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 2170
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="c"
/db_xref="dbSNP:370981396"
variation 2172
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:147227102"
variation 2268
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:45492700"
exon 2276..2430
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 2301..2302
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace=""
/replace="a"
/db_xref="dbSNP:11484096"
variation 2302..2303
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace=""
/replace="a"
/db_xref="dbSNP:34975251"
variation 2331
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="c"
/db_xref="dbSNP:200073364"
variation 2348
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:369668806"
variation 2394
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:373550621"
variation 2415
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:142083540"
exon 2431..2595
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 2449
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:140292070"
variation 2469
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:3761170"
variation 2475
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:189186909"
variation 2499
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:139095432"
variation 2514
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:3761169"
variation 2578
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="g"
/db_xref="dbSNP:61755434"
variation 2586
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:8118206"
exon 2596..2695
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 2666
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:377440334"
variation 2673
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="g"
/replace="t"
/db_xref="dbSNP:202079822"
exon 2696..2800
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 2715
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:145778961"
variation 2717
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:6086575"
variation 2738
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:112272450"
variation 2741
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:202199288"
variation 2792
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:377053037"
exon 2801..2910
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 2861
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:146646749"
variation 2899
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:144264179"
exon 2911..3043
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 2937
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="g"
/replace="t"
/db_xref="dbSNP:141433824"
variation 2938
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="g"
/db_xref="dbSNP:368627128"
variation 2951
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:201764744"
variation 2952
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:2076413"
variation 2957
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:184436336"
variation 2975
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="g"
/db_xref="dbSNP:148288081"
exon 3044..3097
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 3060
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="g"
/replace="t"
/db_xref="dbSNP:142813933"
exon 3098..3317
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 3115
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:147055196"
variation 3165
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="g"
/db_xref="dbSNP:138373296"
variation 3184
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="g"
/db_xref="dbSNP:143664316"
variation 3185
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:147191017"
variation 3197
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:113429373"
variation 3228
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:35245209"
variation 3240
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="g"
/db_xref="dbSNP:202226833"
variation 3255
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:149312175"
variation 3294
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:368328261"
variation 3307
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="c"
/db_xref="dbSNP:372269921"
exon 3318..3498
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 3333
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:369387650"
variation 3334
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:371547145"
variation 3354
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:45464693"
variation 3366
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:148394888"
variation 3374
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="c"
/db_xref="dbSNP:142497580"
variation 3375
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:2235613"
variation 3426
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:139859188"
exon 3499..3575
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 3503
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:75820839"
variation 3507
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:61755436"
variation 3516
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:141102170"
exon 3576..3665
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 3589
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:41275588"
variation 3621
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="g"
/replace="t"
/db_xref="dbSNP:58386879"
exon 3666..3723
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 3687
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="g"
/replace="t"
/db_xref="dbSNP:370182417"
variation 3691
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:376179077"
exon 3724..3810
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 3724
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:2294597"
variation 3734
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:148936543"
exon 3811..7089
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/inference="alignment:Splign:1.39.8"
variation 3834
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:142432676"
STS 3839..4036
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/standard_name="A007B46"
/db_xref="UniSTS:3741"
variation 3899
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:145966488"
variation 3906
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:369783351"
STS 3914..4015
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/standard_name="D20S580E"
/db_xref="UniSTS:7842"
variation 3920
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:200309017"
variation 3933
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:148236379"
variation 3937
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:28390202"
variation 3956
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="g"
/db_xref="dbSNP:200781362"
variation 3971
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:186429469"
variation 3976
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="t"
/db_xref="dbSNP:199568969"
variation 3977
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:190019296"
variation 3993
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="g"
/db_xref="dbSNP:200558916"
variation 3994
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:150804955"
variation 4022
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:202009902"
STS 4028..4179
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/standard_name="D20S594E"
/db_xref="UniSTS:37163"
variation 4030
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:138077430"
variation 4064
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:142723816"
variation 4080
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:368625100"
variation 4086
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="c"
/db_xref="dbSNP:372734005"
variation 4129
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace=""
/replace="c"
/db_xref="dbSNP:146432082"
variation 4135
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:41275590"
variation 4196
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="t"
/db_xref="dbSNP:41275592"
variation 4206
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="t"
/db_xref="dbSNP:138231814"
variation 4295
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="t"
/db_xref="dbSNP:374099954"
variation 4333
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:376353155"
variation 4391
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:182132458"
variation 4414..4415
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace=""
/replace="aat"
/db_xref="dbSNP:147873196"
variation 4415..4416
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace=""
/replace="aat"
/replace="ata"
/db_xref="dbSNP:369758360"
variation 4420
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:187192857"
variation 4501
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:6039314"
variation 4635
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:370143156"
variation 4645
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:192618264"
variation 4787
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="g"
/db_xref="dbSNP:16995375"
variation 4829
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:6077450"
variation 4893
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:115731722"
variation 4962
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:6077451"
variation 4977
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:6056227"
variation 4980
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:41275594"
variation 5000
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:41275596"
variation 5029
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="c"
/db_xref="dbSNP:139726114"
variation 5066
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="t"
/db_xref="dbSNP:188506001"
variation 5212..5213
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace=""
/replace="g"
/db_xref="dbSNP:34193042"
variation 5233
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:377303019"
variation 5284..5285
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace=""
/replace="tt"
/db_xref="dbSNP:373951022"
variation 5379..5381
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace=""
/replace="aat"
/db_xref="dbSNP:200025372"
STS 5385..5532
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/standard_name="A006R17"
/db_xref="UniSTS:39851"
variation 5576
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="g"
/replace="t"
/db_xref="dbSNP:116163517"
variation 5589
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:77690948"
variation 5615
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace=""
/replace="a"
/db_xref="dbSNP:111518686"
variation 5682
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:193061195"
variation 5708
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:41275598"
variation 5719
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:1047381"
variation 5745
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:708910"
variation 5836
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="g"
/replace="t"
/db_xref="dbSNP:73089700"
variation 5845
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:185730557"
variation 5902
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="g"
/db_xref="dbSNP:6056228"
variation 5909
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:200559753"
variation 5940
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="g"
/replace="t"
/db_xref="dbSNP:189287307"
variation 5991..5994
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace=""
/replace="actt"
/db_xref="dbSNP:140751915"
variation 5992..5995
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace=""
/replace="ctta"
/db_xref="dbSNP:78940282"
variation 6014..6015
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace=""
/replace="tctt"
/db_xref="dbSNP:202098034"
variation 6034
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:11906786"
variation 6078
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:191314641"
variation 6134..6136
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace=""
/replace="gaa"
/db_xref="dbSNP:140743311"
variation 6237
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="g"
/db_xref="dbSNP:139585499"
variation 6533
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:113838596"
variation 6548
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:1047383"
variation 6623
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="c"
/replace="t"
/db_xref="dbSNP:41275600"
variation 6750..6751
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace=""
/replace="c"
/db_xref="dbSNP:35474573"
STS 6783..6880
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/standard_name="RH78853"
/db_xref="UniSTS:46819"
variation 6827
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:188626146"
variation 6910
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="g"
/db_xref="dbSNP:181420228"
variation 6938
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="g"
/replace="t"
/db_xref="dbSNP:374699222"
variation 6973
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
/replace="a"
/replace="t"
/db_xref="dbSNP:186428545"
polyA_signal 7069..7074
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
polyA_site 7089
/gene="PLCB1"
/gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
PLCB1A; PLCB1B"
ORIGIN
cactcgctctctccctctgtgtatagaggatgtgctgaatggtgcgctttgaggcggcggcggcggaggagcagaatccgccgcgactggcagcctcggctgaccggctcggcttctcttcgccttccgaggctcctcatccaccgcgggctccagacctcgcgtcccgcccggggcatggccgggcgctgcgcccccgcgcgctctgcctgctgagcggcgccggagggaggtgcggaggccgggaggccggggaggccggcggggagcagagtcgagcgcctccggagcagagaaaggagcccgcgccccgcgccccgcgccccgcgcacggtccccagtccctgccgcgctcgcccgggccgcccggagcccagatgagcccagatggccggggctcaacccggagtgcacgccttgcaactcaagcccgtgtgcgtgtccgacagcctcaagaagggcaccaaattcgtcaagtgggatgatgactcaactattgttactccaattattttgaggactgaccctcagggatttttcttttactggacagatcaaaacaaggagacagagctactggatctcagccttgtcaaagatgccagatgtgggagacacgccaaagctcccaaggaccccaaattacgtgaacttttggatgtggggaacatcgggcgcctggagcagcgcatgatcacagtggtgtatgggcctgacctcgtgaacatctcccatttgaatctcgtggctttccaagaagaagtggccaaggaatggacaaatgaggttttcagtttggcaacaaacctgctggcccaaaacatgtccagggatgcatttctggaaaaagcctatactaaacttaagctgcaagtcactccagaagggcgtattcctctcaaaaacatatatcgcttgttttcagcagatcggaagcgagttgaaactgctttagaggcttgtagtcttccatcttcaaggaatgattcaatacctcaagaagatttcactccagaagtgtacagagttttcctcaacaacctttgccctcgacctgaaattgataacatcttttcagaatttggtgcaaaaagcaaaccatatcttaccgttgatcagatgatggattttatcaaccttaagcagcgagatcctcggcttaatgaaatactttatccacctctaaaacaagagcaagtccaagtattgattgagaagtatgaacccaacaacagcctcgccagaaaaggacaaatatcagtggatgggttcatgcgctatctgagtggagaagaaaacggagtcgtttcacctgagaaactggatttgaatgaagacatgtctcagcccctttctcactatttcattaattcctcgcacaacacctacctcacagctggccaactggctggaaactcctctgttgagatgtatcgccaagtgctcctgtctggttgtcgctgtgtggagctggactgctggaagggacggactgcagaagaggaacctgtcatcacccatggcttcaccatgacaactgaaatatctttcaaggaagtgatagaagcaattgcggagtgtgcatttaagacttcaccttttccaattctcctttcgtttgagaaccatgtggattccccaaagcagcaagccaagatggcggagtactgccgactgatctttggggatgcccttctcatggagcccctggaaaaatatccactggaatctggagttcctcttccaagccctatggatttaatgtataaaattttggtgaaaaataagaagaaatcacacaagtcatcagaaggaagcggcaaaaagaagctctcagaacaagcctccaacacctacagtgactcctccagcatgttcgagccctcatccccaggagccggagaagctgatacggaaagtgacgacgacgatgatgatgatgactgtaaaaaatcttcaatggatgaggggactgctggaagtgaggctatggccacagaagaaatgtctaatctggtgaactatattcagccagtcaagtttgagtcatttgaaatttcaaaaaaaagaaataaaagttttgaaatgtcttccttcgtggaaaccaaaggacttgaacaactcaccaagtctccagtggaatttgtagaatataacaaaatgcagcttagcaggatatatccaaaaggaacacgtgtggattcatccaactatatgcctcagctcttctggaatgcaggttgtcagatggtggcacttaatttccagacaatggacctggctatgcaaataaatatggggatgtatgaatacaacgggaagagtggctacagattgaagccagagttcatgaggaggcctgacaagcattttgatccatttactgaaggcatcgtagatgggatagtggcaaacactttgtctgttaagattatttcaggtcagtttctttctgataagaaagttgggacttacgtggaagtagatatgtttggtttgcctgtggatacaaggaggaaggcatttaagaccaaaacatcccaaggaaatgctgtgaatcctgtctgggaagaagaacctattgtgttcaaaaaggtggttcttcctactctggcctgtttgagaatagcagtttatgaagaaggaggtaaattcattggccaccgtatcttgccagtgcaagccattcggccaggctatcactatatctgtctaaggaatgaaaggaaccagcctctgacgctgcctgctgtctttgtctacatagaagtgaaagactatgtgccagacacatatgcagatgtcatcgaagctttatcaaacccaatccgatatgtgaacctgatggaacagagagctaagcaattggctgctttgacactggaagatgaagaagaagtaaagaaagaggctgatcctggagaaacaccatcagaggctccaagtgaagcgagaacgactccagcagaaaatggggtgaatcacactacaaccctgacacccaagccaccctcccaggctctccacagccagccagctccaggttctgtaaaggcacctgccaaaacagaagatcttattcagagtgtcttaacagaagtggaagcacagaccatcgaagaactaaagcaacagaaatcgtttgtgaaacttcaaaagaaacactacaaagaaatgaaagacctggttaagagacaccacaagaaaaccactgaccttatcaaagaacacactaccaagtataatgaaattcagaatgactacttgagaaggagagccgctttggaaaagtccgccaaaaaggacagtaagaaaaaatcggaacccagcagccctgatcatggttcatcaacgattgagcaagacctcgctgctctggatgctgaaatgacccaaaagttaatagacttgaaggacaaacaacagcagcagctgcttaatcttcggcaagaacagtattatagtgaaaaataccagaagcgagaacatattaaactgcttattcaaaagttgacggatgtcgcagaagagtgtcagaacaatcagttaaagaagctcaaagaaatctgtgagaaagaaaagaaagaattaaagaagaaaatggataaaaagaggcaggagaagataacagaagctaaatccaaagacaaaagtcagatggaagaggagaagacagagatgatccggtcatatatccaggaagtggtgcagtatatcaagaggctagaagaagcgcaaagtaaacggcaagaaaaactcgtagagaaacacaaggaaatacgtcagcagatcctggatgaaaagcccaagctgcaggtggagctggagcaagaataccaagacaaattcaaaagactgcccctcgagattttggaattcgtgcaggaagccatgaaaggaaagatcagtgaagacagcaatcacggttctgcccctctctccctgtcctcagaccctggaaaagtgaaccacaagactccctccagtgaggagctgggaggagacatcccaggaaaagaatttgatactcctctgtgaatgctcctgccaggccttcagaaattgcatggccactccagcgtcatcggactctctcttattacaaagatcactgcccaggaccatcttcccgagaagcatcccttagcctaaaatccacaccaaagggagagttccagaggaatccatgaagaattcccatgcccaggctccatgtgtcatgtggaaacctccacaggtctgctagtgaagaatgcatgtatgtgagatttttgttttctttccaatagcaaattcaaagcaagcaacttgcaggctccatggaacttttaatgaaggacagtgtcttctttgaagaaaatcaagctcgtgtttttattcgaagctctggtgtaaaatatttcaaagtcatagaaatagtttgagaaatgcatagcattatttaacactattgaacagccgactttgagcattgtttcttctaactgcccctcaactaccattatcttcaagtcaacatgcatattacattttcatcctttgctttgcaagcactggtggcttgcagtttgctaatttatttatcatagagtcatcaatgtatttgttgctgacatggttttattagatactgtagtgattcaaataagttttctatttgaaaaaaaaaatcacttgattgtatccttgcccagtgaagccatcctaagacttagcaatatggattgtacatttggctgcatgagcaagtcggccgcacacttccagacagtgtgctgtttgaattgactatttgcactcaaagtctgggtattcattggttattggcctgaaatgatcaaataactacaaatgatctgttgaataaaaatagttgagctgatatatgttaagcagatattcaatcagaatgaacaggttccggtggttattttgccgtttgacattttttatggttcatttatttttaatatagagaggaagattgaatatttatctagagaatacaaagacccacatgtaaatgataggtattatctccatgtatatatgtacccacttagtcatgtaagtgcatatacacatacacacacatgagtgtagacatgtgtttattaattgacaatgacccaaatctcttccacaagacttaaaaccaaattcagggacaaatggatagagaagaaaagggtcaaacatcgagattacatggatgttaaattatatggagacgctaagaaataattgatggagccattgatgcaaaccgaagtagatttagaacttatatgaatttgatttatattttgcaagatcaaaaattagatgttaagtatcagattttaagcttgttttaatggtcaaaaaattaggacagaaataatatggacatttattagtatcttccataatttttaagtctgacacatttctattttattctaacataaaaaaacttccattatatatttactaagtatatttaattcacttaactctgtctttataagttcctattttagatggaataagagaaacaaattatatcaaggtaaaactgatcaaaagcataattgaaagttctgaaaaaagaaaaataataatatgtagaaaaatgtaacttagagagtaacacatgaacattgaagttaaaacccagaagccagatgctcacagttttattttactttaaaataaacctgtctgactgtagctttgtgaaatatcttaaaacgcaaaaaccaattgtgtcctgaaaattgtttcaagaatttaatatttttatgaaaattattttatttaactttaagcaataactagagattacaattaaattttaatcaaaatgaaggcttagttcaaacataaggaaacagtgtttgattaaaaaaaacacatctagtaagacgtaaggggaaaatcacatcctctttggagatgattatattttgatctgaagggtttggggtgttcattagacacttaataaaacttaacttccaatgaaaaagaaatcttttgtaaatcattctacttttgcactttgaaagaaaggcgttaatcataaagaagcaagaatggtcaaaatcgaatgctgcatttttataaacaaaattacagactgtctgaaattgaagaagaatgaactaataatagcattcataaccaaacacaatgatgattattgcagaacattgtatcacattttagtccagagatagaataaagttgaataaccttgacttacacaaaactgttttggtagttggatttcattatcttagtgaatttagtcattttacaatatgtttgtatttggccatttactgtaatcacatttttatatctgtacaatgacactttttgcagttgtggggtagtgtgtaacactgtccatcttgcatcattgaaactactacaatgatactatcatttaataatattaatattacttgaaatagactaagataaagaaaaggggtctgtatgatgtgcagttttgtgcctttatgtatttgccttgttctttgtcgaatgtgtgaaattccgtactgtggtttttcctataatagaaagtagagctgtgtattaaattagactgtgtctctctgatacctttacactactgagaatagcatggttttggccatgtaaaccaattttcaaagttctaatgacatagccatgtgtttttggttttttatatttcattttaaaatttgagtatcaccatacattaattaatactcctgtagtagataagctgtcattaagtaattcccaaaaaaagggccatttgcttgcattactttgaatttaatgttgcgcttgtgcactgtgttaatattgtttgtgatggattggacgttgtgactcttgccttttaagaagaaaaaaaagataggacaaagtatttgaagctcttaaaatgtacatattttggttcttctatctcaaattatttaaaatgcataattcacatttttgtaataattctatgcaattttgtggcatgatgtttcttccacttgtaattttatgtgctttcatcacaaatccaaaggaaagaataaaaatttcttaacacaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:23236 -> Molecular function: GO:0004435 [phosphatidylinositol phospholipase C activity] evidence: ISS
GeneID:23236 -> Molecular function: GO:0004435 [phosphatidylinositol phospholipase C activity] evidence: NAS
GeneID:23236 -> Molecular function: GO:0004871 [signal transducer activity] evidence: IEA
GeneID:23236 -> Molecular function: GO:0005096 [GTPase activator activity] evidence: IDA
GeneID:23236 -> Molecular function: GO:0005509 [calcium ion binding] evidence: IEA
GeneID:23236 -> Molecular function: GO:0005516 [calmodulin binding] evidence: IPI
GeneID:23236 -> Molecular function: GO:0005521 [lamin binding] evidence: IEA
GeneID:23236 -> Molecular function: GO:0005546 [phosphatidylinositol-4,5-bisphosphate binding] evidence: IDA
GeneID:23236 -> Molecular function: GO:0019899 [enzyme binding] evidence: IPI
GeneID:23236 -> Molecular function: GO:0042803 [protein homodimerization activity] evidence: ISS
GeneID:23236 -> Biological process: GO:0000086 [G2/M transition of mitotic cell cycle] evidence: ISS
GeneID:23236 -> Biological process: GO:0007165 [signal transduction] evidence: NAS
GeneID:23236 -> Biological process: GO:0007213 [G-protein coupled acetylcholine receptor signaling pathway] evidence: ISS
GeneID:23236 -> Biological process: GO:0007215 [glutamate receptor signaling pathway] evidence: ISS
GeneID:23236 -> Biological process: GO:0007268 [synaptic transmission] evidence: TAS
GeneID:23236 -> Biological process: GO:0007613 [memory] evidence: ISS
GeneID:23236 -> Biological process: GO:0008277 [regulation of G-protein coupled receptor protein signaling pathway] evidence: ISS
GeneID:23236 -> Biological process: GO:0016042 [lipid catabolic process] evidence: IEA
GeneID:23236 -> Biological process: GO:0021987 [cerebral cortex development] evidence: ISS
GeneID:23236 -> Biological process: GO:0032735 [positive regulation of interleukin-12 production] evidence: ISS
GeneID:23236 -> Biological process: GO:0035556 [intracellular signal transduction] evidence: IEA
GeneID:23236 -> Biological process: GO:0035722 [interleukin-12-mediated signaling pathway] evidence: IDA
GeneID:23236 -> Biological process: GO:0035723 [interleukin-15-mediated signaling pathway] evidence: IDA
GeneID:23236 -> Biological process: GO:0040019 [positive regulation of embryonic development] evidence: ISS
GeneID:23236 -> Biological process: GO:0043547 [positive regulation of GTPase activity] evidence: IDA
GeneID:23236 -> Biological process: GO:0043647 [inositol phosphate metabolic process] evidence: TAS
GeneID:23236 -> Biological process: GO:0044281 [small molecule metabolic process] evidence: TAS
GeneID:23236 -> Biological process: GO:0045444 [fat cell differentiation] evidence: IEA
GeneID:23236 -> Biological process: GO:0045663 [positive regulation of myoblast differentiation] evidence: ISS
GeneID:23236 -> Biological process: GO:0045892 [negative regulation of transcription, DNA-dependent] evidence: ISS
GeneID:23236 -> Biological process: GO:0045893 [positive regulation of transcription, DNA-dependent] evidence: ISS
GeneID:23236 -> Biological process: GO:0046330 [positive regulation of JNK cascade] evidence: IDA
GeneID:23236 -> Biological process: GO:0046488 [phosphatidylinositol metabolic process] evidence: ISS
GeneID:23236 -> Biological process: GO:0048009 [insulin-like growth factor receptor signaling pathway] evidence: ISS
GeneID:23236 -> Biological process: GO:0048639 [positive regulation of developmental growth] evidence: ISS
GeneID:23236 -> Biological process: GO:0060466 [activation of meiosis involved in egg activation] evidence: ISS
GeneID:23236 -> Biological process: GO:0070498 [interleukin-1-mediated signaling pathway] evidence: IDA
GeneID:23236 -> Biological process: GO:0080154 [regulation of fertilization] evidence: ISS
GeneID:23236 -> Biological process: GO:1900087 [positive regulation of G1/S transition of mitotic cell cycle] evidence: ISS
GeneID:23236 -> Biological process: GO:2000344 [positive regulation of acrosome reaction] evidence: ISS
GeneID:23236 -> Biological process: GO:2000438 [negative regulation of monocyte extravasation] evidence: ISS
GeneID:23236 -> Biological process: GO:2000560 [positive regulation of CD24 biosynthetic process] evidence: ISS
GeneID:23236 -> Cellular component: GO:0000790 [nuclear chromatin] evidence: ISS
GeneID:23236 -> Cellular component: GO:0005634 [nucleus] evidence: NAS
GeneID:23236 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:23236 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:23236 -> Cellular component: GO:0016607 [nuclear speck] evidence: IDA
GeneID:23236 -> Cellular component: GO:0031965 [nuclear membrane] evidence: IEA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_056007 -> EC 3.1.4.11
by
@meso_cacase at
DBCLS
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