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2024-04-24 21:37:09, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_015170 5710 bp mRNA linear PRI 12-MAY-2013
DEFINITION Homo sapiens sulfatase 1 (SULF1), transcript variant 3, mRNA.
ACCESSION NM_015170
VERSION NM_015170.2 GI:189571635
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5710)
AUTHORS Hur,K., Han,T.S., Jung,E.J., Yu,J., Lee,H.J., Kim,W.H., Goel,A. and
Yang,H.K.
TITLE Up-regulated expression of sulfatases (SULF1 and SULF2) as
prognostic and metastasis predictive markers in human gastric
cancer
JOURNAL J. Pathol. 228 (1), 88-98 (2012)
PUBMED 22653794
REMARK GeneRIF: SULF1 may serve as a promising biomarker for patients with
gastric carcinoma.
REFERENCE 2 (bases 1 to 5710)
AUTHORS Manning,A.K., Hivert,M.F., Scott,R.A., Grimsby,J.L.,
Bouatia-Naji,N., Chen,H., Rybin,D., Liu,C.T., Bielak,L.F.,
Prokopenko,I., Amin,N., Barnes,D., Cadby,G., Hottenga,J.J.,
Ingelsson,E., Jackson,A.U., Johnson,T., Kanoni,S., Ladenvall,C.,
Lagou,V., Lahti,J., Lecoeur,C., Liu,Y., Martinez-Larrad,M.T.,
Montasser,M.E., Navarro,P., Perry,J.R., Rasmussen-Torvik,L.J.,
Salo,P., Sattar,N., Shungin,D., Strawbridge,R.J., Tanaka,T., van
Duijn,C.M., An,P., de Andrade,M., Andrews,J.S., Aspelund,T.,
Atalay,M., Aulchenko,Y., Balkau,B., Bandinelli,S., Beckmann,J.S.,
Beilby,J.P., Bellis,C., Bergman,R.N., Blangero,J., Boban,M.,
Boehnke,M., Boerwinkle,E., Bonnycastle,L.L., Boomsma,D.I.,
Borecki,I.B., Bottcher,Y., Bouchard,C., Brunner,E., Budimir,D.,
Campbell,H., Carlson,O., Chines,P.S., Clarke,R., Collins,F.S.,
Corbaton-Anchuelo,A., Couper,D., de Faire,U., Dedoussis,G.V.,
Deloukas,P., Dimitriou,M., Egan,J.M., Eiriksdottir,G., Erdos,M.R.,
Eriksson,J.G., Eury,E., Ferrucci,L., Ford,I., Forouhi,N.G.,
Fox,C.S., Franzosi,M.G., Franks,P.W., Frayling,T.M., Froguel,P.,
Galan,P., de Geus,E., Gigante,B., Glazer,N.L., Goel,A., Groop,L.,
Gudnason,V., Hallmans,G., Hamsten,A., Hansson,O., Harris,T.B.,
Hayward,C., Heath,S., Hercberg,S., Hicks,A.A., Hingorani,A.,
Hofman,A., Hui,J., Hung,J., Jarvelin,M.R., Jhun,M.A., Johnson,P.C.,
Jukema,J.W., Jula,A., Kao,W.H., Kaprio,J., Kardia,S.L.,
Keinanen-Kiukaanniemi,S., Kivimaki,M., Kolcic,I., Kovacs,P.,
Kumari,M., Kuusisto,J., Kyvik,K.O., Laakso,M., Lakka,T.,
Lannfelt,L., Lathrop,G.M., Launer,L.J., Leander,K., Li,G., Lind,L.,
Lindstrom,J., Lobbens,S., Loos,R.J., Luan,J., Lyssenko,V., Magi,R.,
Magnusson,P.K., Marmot,M., Meneton,P., Mohlke,K.L., Mooser,V.,
Morken,M.A., Miljkovic,I., Narisu,N., O'Connell,J., Ong,K.K.,
Oostra,B.A., Palmer,L.J., Palotie,A., Pankow,J.S., Peden,J.F.,
Pedersen,N.L., Pehlic,M., Peltonen,L., Penninx,B., Pericic,M.,
Perola,M., Perusse,L., Peyser,P.A., Polasek,O., Pramstaller,P.P.,
Province,M.A., Raikkonen,K., Rauramaa,R., Rehnberg,E., Rice,K.,
Rotter,J.I., Rudan,I., Ruokonen,A., Saaristo,T., Sabater-Lleal,M.,
Salomaa,V., Savage,D.B., Saxena,R., Schwarz,P., Seedorf,U.,
Sennblad,B., Serrano-Rios,M., Shuldiner,A.R., Sijbrands,E.J.,
Siscovick,D.S., Smit,J.H., Small,K.S., Smith,N.L., Smith,A.V.,
Stancakova,A., Stirrups,K., Stumvoll,M., Sun,Y.V., Swift,A.J.,
Tonjes,A., Tuomilehto,J., Trompet,S., Uitterlinden,A.G.,
Uusitupa,M., Vikstrom,M., Vitart,V., Vohl,M.C., Voight,B.F.,
Vollenweider,P., Waeber,G., Waterworth,D.M., Watkins,H.,
Wheeler,E., Widen,E., Wild,S.H., Willems,S.M., Willemsen,G.,
Wilson,J.F., Witteman,J.C., Wright,A.F., Yaghootkar,H.,
Zelenika,D., Zemunik,T., Zgaga,L., Wareham,N.J., McCarthy,M.I.,
Barroso,I., Watanabe,R.M., Florez,J.C., Dupuis,J., Meigs,J.B. and
Langenberg,C.
CONSRTM DIAbetes Genetics Replication And Meta-analysis (DIAGRAM)
Consortium; Multiple Tissue Human Expression Resource (MUTHER)
Consortium
TITLE A genome-wide approach accounting for body mass index identifies
genetic variants influencing fasting glycemic traits and insulin
resistance
JOURNAL Nat. Genet. 44 (6), 659-669 (2012)
PUBMED 22581228
REMARK Publication Status: Online-Only
REFERENCE 3 (bases 1 to 5710)
AUTHORS Zhang,H., Newman,D.R. and Sannes,P.L.
TITLE HSULF-1 inhibits ERK and AKT signaling and decreases cell viability
in vitro in human lung epithelial cells
JOURNAL Respir. Res. 13, 69 (2012)
PUBMED 22873647
REMARK GeneRIF: HSULF-1 is expressed at lower levels in H292 lung cancer
cells than in normal human alveolar cells and that its
over-expression reduced cell viability in H292 cells by inducing
apoptotic pathways, at least in part by inhibiting ERK/Akt
signaling
Publication Status: Online-Only
REFERENCE 4 (bases 1 to 5710)
AUTHORS Gopal,G., Shirley,S., Raja,U.M. and Rajkumar,T.
TITLE Endo-sulfatase Sulf-1 protein expression is down-regulated in
gastric cancer
JOURNAL Asian Pac. J. Cancer Prev. 13 (2), 641-646 (2012)
PUBMED 22524839
REMARK GeneRIF: Sulf-1 protein expression is down-regulated in gastric
cancer.
REFERENCE 5 (bases 1 to 5710)
AUTHORS N'Diaye,A., Chen,G.K., Palmer,C.D., Ge,B., Tayo,B., Mathias,R.A.,
Ding,J., Nalls,M.A., Adeyemo,A., Adoue,V., Ambrosone,C.B.,
Atwood,L., Bandera,E.V., Becker,L.C., Berndt,S.I., Bernstein,L.,
Blot,W.J., Boerwinkle,E., Britton,A., Casey,G., Chanock,S.J.,
Demerath,E., Deming,S.L., Diver,W.R., Fox,C., Harris,T.B.,
Hernandez,D.G., Hu,J.J., Ingles,S.A., John,E.M., Johnson,C.,
Keating,B., Kittles,R.A., Kolonel,L.N., Kritchevsky,S.B., Le
Marchand,L., Lohman,K., Liu,J., Millikan,R.C., Murphy,A.,
Musani,S., Neslund-Dudas,C., North,K.E., Nyante,S., Ogunniyi,A.,
Ostrander,E.A., Papanicolaou,G., Patel,S., Pettaway,C.A.,
Press,M.F., Redline,S., Rodriguez-Gil,J.L., Rotimi,C.,
Rybicki,B.A., Salako,B., Schreiner,P.J., Signorello,L.B.,
Singleton,A.B., Stanford,J.L., Stram,A.H., Stram,D.O., Strom,S.S.,
Suktitipat,B., Thun,M.J., Witte,J.S., Yanek,L.R., Ziegler,R.G.,
Zheng,W., Zhu,X., Zmuda,J.M., Zonderman,A.B., Evans,M.K., Liu,Y.,
Becker,D.M., Cooper,R.S., Pastinen,T., Henderson,B.E.,
Hirschhorn,J.N., Lettre,G. and Haiman,C.A.
TITLE Identification, replication, and fine-mapping of Loci associated
with adult height in individuals of african ancestry
JOURNAL PLoS Genet. 7 (10), E1002298 (2011)
PUBMED 21998595
REMARK Erratum:[PLoS Genet. 2011 Nov;7(11).
doi:10.1371/annotation/58c67154-3f10-4155-9085-dcd6e3689008]
REFERENCE 6 (bases 1 to 5710)
AUTHORS Dai,Y., Yang,Y., MacLeod,V., Yue,X., Rapraeger,A.C., Shriver,Z.,
Venkataraman,G., Sasisekharan,R. and Sanderson,R.D.
TITLE HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth
in vivo
JOURNAL J. Biol. Chem. 280 (48), 40066-40073 (2005)
PUBMED 16192265
REMARK GeneRIF: HSulf-1 and HSulf-2 have roles in inhibiting myeloma tumor
growth
GeneRIF: HSulf-1 (SULF1) and HSulf-2 (SULF2) are potent inhibitors
of myeloma tumor growth in vivo.
REFERENCE 7 (bases 1 to 5710)
AUTHORS Li,J., Kleeff,J., Abiatari,I., Kayed,H., Giese,N.A., Felix,K.,
Giese,T., Buchler,M.W. and Friess,H.
TITLE Enhanced levels of Hsulf-1 interfere with heparin-binding growth
factor signaling in pancreatic cancer
JOURNAL Mol. Cancer 4 (1), 14 (2005)
PUBMED 15817123
REMARK GeneRIF: High expression of Hsulf-1 occurs in the stromal elements
as well as in the tumor cells in pancreatic cancer and interferes
with heparin-binding growth factor signaling
Publication Status: Online-Only
REFERENCE 8 (bases 1 to 5710)
AUTHORS Lai,J.P., Chien,J.R., Moser,D.R., Staub,J.K., Aderca,I.,
Montoya,D.P., Matthews,T.A., Nagorney,D.M., Cunningham,J.M.,
Smith,D.I., Greene,E.L., Shridhar,V. and Roberts,L.R.
TITLE hSulf1 Sulfatase promotes apoptosis of hepatocellular cancer cells
by decreasing heparin-binding growth factor signaling
JOURNAL Gastroenterology 126 (1), 231-248 (2004)
PUBMED 14699503
REMARK GeneRIF: Down-regulation of hSulf1 contributes to
hepatocarcinogenesis by enhancing heparin-binding growth factor
signaling and resistance to apoptosis.
REFERENCE 9 (bases 1 to 5710)
AUTHORS Lai,J., Chien,J., Staub,J., Avula,R., Greene,E.L., Matthews,T.A.,
Smith,D.I., Kaufmann,S.H., Roberts,L.R. and Shridhar,V.
TITLE Loss of HSulf-1 up-regulates heparin-binding growth factor
signaling in cancer
JOURNAL J. Biol. Chem. 278 (25), 23107-23117 (2003)
PUBMED 12686563
REMARK GeneRIF: modulates signaling by heparin-binding growth factors, and
HSulf-1 down-regulation represents a novel mechanism by which
cancer cells can enhance growth factor signaling
REFERENCE 10 (bases 1 to 5710)
AUTHORS Morimoto-Tomita,M., Uchimura,K., Werb,Z., Hemmerich,S. and
Rosen,S.D.
TITLE Cloning and characterization of two extracellular heparin-degrading
endosulfatases in mice and humans
JOURNAL J. Biol. Chem. 277 (51), 49175-49185 (2002)
PUBMED 12368295
REMARK GeneRIF: Sulfs are extracellular endosulfatases with strong
potential for modulating the interactions of heparan sulfate
proteoglycans in the extracellular microenvironment
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
DA745191.1, AY101175.1 and AF545571.1.
On Jun 10, 2008 this sequence version replaced gi:29789063.
Summary: Heparan sulfate proteoglycans (HSPGs) act as coreceptors
for numerous heparin-binding growth factors and cytokines and are
involved in cell signaling. Heparan sulfate 6-O-endosulfatases,
such as SULF1, selectively remove 6-O-sulfate groups from heparan
sulfate. This activity modulates the effects of heparan sulfate by
altering binding sites for signaling molecules (Dai et al., 2005
[PubMed 16192265]).[supplied by OMIM, Mar 2008].
Transcript Variant: This variant (3) differs in the 5' UTR compared
to variant 1. Variants 1-4 encode the same protein.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
CDS exon combination :: AF545571.1, BX571746.1 [ECO:0000331]
RNAseq introns :: single sample supports all introns
ERS025084, ERS025085 [ECO:0000348]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-563 DA745191.1 1-563
564-3875 AY101175.1 355-3666
3876-5710 AF545571.1 3865-5699
FEATURES Location/Qualifiers
source 1..5710
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="8"
/map="8q13.1"
gene 1..5710
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="sulfatase 1"
/db_xref="GeneID:23213"
/db_xref="HGNC:20391"
/db_xref="MIM:610012"
exon 1..327
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 108
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:372014979"
variation 125
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:376584503"
variation 176
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:187842089"
exon 328..489
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 344
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:190710581"
variation 466
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="t"
/db_xref="dbSNP:142022282"
exon 490..584
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 498
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:185882678"
variation 541
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:13264163"
variation 562
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148950847"
exon 585..657
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
misc_feature 649..651
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="upstream in-frame stop codon"
exon 658..889
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 673
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:376187821"
variation 708
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:369974279"
CDS 718..3333
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="sulfatase FP; extracellular sulfatase Sulf-1"
/codon_start=1
/product="extracellular sulfatase Sulf-1 precursor"
/protein_id="NP_055985.2"
/db_xref="GI:189571636"
/db_xref="CCDS:CCDS6204.1"
/db_xref="GeneID:23213"
/db_xref="HGNC:20391"
/db_xref="MIM:610012"
/translation="
MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVLNIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKEESSKNIQQSNHLPKYERVKELCQQARYQTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLLTVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPKYKPRFVHTRQTRSLSVEFEGEIYDINLEEEEELQVLQPRNIAKRHDEGHKGPRDLQASSGGNRGRMLADSSNAVGPPTTVRVTHKCFILPNDSIHCERELYQSARAWKDHKAYIDKEIEALQDKIKNLREVRGHLKRRKPEECSCSKQSYYNKEKGVKKQEKLKSHLHPFKEAAQEVDSKLQLFKENNRRRKKERKEKRRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWCLRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHVQLMELRSCQGYKQCNPRPKNLDVGNKDGGSYDLHRGQLWDGWEG
"
sig_peptide 718..783
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="COORDINATES: ab initio prediction:SignalP:4.0"
mat_peptide 784..3330
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/product="Extracellular sulfatase Sulf-1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q8IWU6.1)"
misc_feature 841..>1899
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="Arylsulfatase A and related enzymes [Inorganic ion
transport and metabolism]; Region: AslA; COG3119"
/db_xref="CDD:32933"
misc_feature 844..1896
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="Sulfatase; Region: Sulfatase; pfam00884"
/db_xref="CDD:201490"
misc_feature 2314..2757
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="Sulfatase protein; Region: DUF3740; pfam12548"
/db_xref="CDD:204957"
variation 779
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="t"
/db_xref="dbSNP:201640007"
variation 786
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201650068"
variation 800
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:376825615"
variation 815
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:145127325"
variation 831
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="t"
/db_xref="dbSNP:367922640"
variation 832
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:142027500"
variation 870
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:138943816"
exon 890..1129
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 898
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:199820581"
variation 934
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:201774043"
variation 936
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:141505559"
variation 968
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:113938874"
variation 984
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:6984529"
variation 989
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:149786573"
variation 999
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:377416230"
variation 1005
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:138186217"
variation 1024
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:200955613"
variation 1025
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370346553"
variation 1044
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370128603"
variation 1065
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370291955"
variation 1088
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:147909650"
exon 1130..1281
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1131
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:149562933"
variation 1158
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:371221472"
variation 1177
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:147245253"
variation 1206
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:199957740"
variation 1239
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:139810682"
variation 1240
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200127043"
variation 1241
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:186655894"
exon 1282..1451
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1356
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:191906713"
variation 1359
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:374058291"
variation 1386
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:111474126"
variation 1389
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:368146472"
variation 1392
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:77728226"
variation 1428
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372034572"
exon 1452..1602
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1497
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:377164865"
variation 1507
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:112367866"
variation 1549
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:202004083"
variation 1566
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:141571826"
variation 1575
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:61746702"
exon 1603..1778
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1605
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:142148202"
variation 1662
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201468946"
variation 1686
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:377634023"
variation 1733
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:61747207"
exon 1779..1907
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1783
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:199804686"
variation 1784
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:374371569"
variation 1792
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:140542311"
variation 1812
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:144010163"
variation 1813
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:201478955"
variation 1818
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:146417849"
variation 1828
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:118056333"
variation 1846
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:201919147"
variation 1849
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:371818580"
variation 1862
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:201782679"
exon 1908..1964
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
exon 1965..2094
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1976
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201100928"
variation 2047
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:145174051"
variation 2088
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:112123068"
variation 2090
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148982651"
exon 2095..2311
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2095
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:199539739"
variation 2109
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:147479634"
variation 2124
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:374949302"
variation 2166
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:367667000"
variation 2176
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372786570"
variation 2184
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148125441"
variation 2186
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:141888575"
variation 2191
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201173589"
variation 2196
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:146435519"
variation 2197
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:368427346"
variation 2198
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:112120588"
variation 2200
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:142971465"
variation 2201
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:372337091"
variation 2211
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:375512132"
variation 2231
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:369545860"
variation 2244
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200268962"
variation 2246
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372839295"
variation 2252
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:202168144"
variation 2256
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:147223148"
variation 2275
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:374818506"
variation 2280
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:368822296"
variation 2306
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:139600896"
exon 2312..2567
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2312
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:149298828"
variation 2339
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370846825"
variation 2362
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201229545"
variation 2438
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:199742300"
variation 2462
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:138876060"
variation 2499
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:370806055"
variation 2504
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:144546726"
variation 2506
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:61747130"
variation 2525
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:61740823"
variation 2529
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:375090509"
variation 2530
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:144030540"
variation 2533
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:146445328"
variation 2537
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:367704931"
variation 2551
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:200550270"
variation 2554
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:370193108"
exon 2568..2664
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2631
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:140509610"
variation 2659
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:376608568"
exon 2665..2759
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
exon 2760..2825
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2769
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370172405"
exon 2826..3001
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2859
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:143120352"
variation 2872..2874
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace=""
/replace="aac"
/db_xref="dbSNP:150178205"
variation 2878
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:377353091"
variation 2879
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369423636"
variation 2882
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:373878204"
variation 2886
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:143386315"
variation 2888
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:199811211"
variation 2912
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:199542001"
variation 3001
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370600729"
exon 3002..3144
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 3024
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:190311964"
variation 3071
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:150467604"
variation 3104
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:145335171"
variation 3111
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:78063897"
variation 3121
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:74480225"
exon 3145..3268
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 3157
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:117639561"
variation 3164
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:111626231"
variation 3194
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="t"
/db_xref="dbSNP:148555931"
variation 3201
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:146601124"
variation 3210
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:368328719"
variation 3248
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:139106228"
variation 3251
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372242544"
variation 3266
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:143009161"
exon 3269..3302
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 3293
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:143631855"
exon 3303..5710
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 3304
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148285446"
variation 3313
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201165394"
variation 3335
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:141331130"
variation 3487
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369995251"
variation 3514..3517
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace=""
/replace="aaat"
/db_xref="dbSNP:112665345"
variation 3570
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:371124844"
variation 3574
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:112715006"
variation 3598
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:77871693"
variation 3623
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:191954863"
variation 3643
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:111938908"
variation 3662
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:148648757"
variation 3722
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:115563984"
variation 3760
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:183717149"
variation 3769
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:75724852"
variation 3781
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:114581461"
variation 3832
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:72660109"
variation 3842
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:187437769"
variation 3876
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:3802278"
variation 3944
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:59068490"
variation 4026
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:139690250"
variation 4030
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:371075932"
variation 4054
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:145279779"
variation 4094
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:6990375"
variation 4138
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:189672278"
variation 4185
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:11996377"
variation 4200
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:1130242"
variation 4275
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:372074006"
variation 4299
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:59364549"
variation 4322
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:182489932"
variation 4328
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:76316652"
variation 4436
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:147649872"
variation 4447
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:187129161"
variation 4519
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:374978465"
variation 4535
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:191896243"
variation 4544
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:367559651"
variation 4566
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:183580848"
variation 4631
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:140433867"
STS 4690..4811
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/standard_name="RH47887"
/db_xref="UniSTS:48570"
variation 4697
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:188265806"
variation 4784
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:193164086"
variation 4810
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:149994968"
variation 4820
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:185376784"
variation 5036
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:189504583"
variation 5237
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="t"
/db_xref="dbSNP:191238908"
STS 5495..5677
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/standard_name="RH98994"
/db_xref="UniSTS:89243"
variation 5498
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372371432"
variation 5567
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:3087714"
ORIGIN
aggttacttgactgggagttctcagacctccagtttcagccctgccctcagcctccaatccgtaagagacacccagccccagcaattggattgggcagcccgtcttgacacaccactgtgctgagtgcttgaggacgtgtttcaacagatggttggggttagtgtgtgtcatcacattcgagtggggattaagagaaggaaggctgccttgctggagctgtgtggtcttctccaagtgagagtcgcaggcaatagaactactttgcttttggaggaaaaggaggaattcattttcagcagacacaagaaaagcagtttttttttcagggattcttcacttctcttgaacaaggaactcactcagagactaacacaaaggaagtaatttcttacctggtcattatttagtctacaataagttcatccttcttcagtgtgaccagtaaattcttcccatactcttgaagagagcataattggaatggagaggtgctgacggccacccaccatcatctaaagaagataaacttggcaaatgacatgcaggttcttcaaggcagaataattgcagaaaatcttcaaaggaccctatctgcagatgttctgaatacctctgagaatagagattgattattcaaccaggatacctaattcaagaactccagaaatcaggagacggagacattttgtcagttttgcaacattggaccaaatacaatgaagtattcttgctgtgctctggttttggctgtcctgggcacagaattgctgggaagcctctgttcgactgtcagatccccgaggttcagaggacggatacagcaggaacgaaaaaacatccgacccaacattattcttgtgcttaccgatgatcaagatgtggagctggggtccctgcaagtcatgaacaaaacgagaaagattatggaacatgggggggccaccttcatcaatgcctttgtgactacacccatgtgctgcccgtcacggtcctccatgctcaccgggaagtatgtgcacaatcacaatgtctacaccaacaacgagaactgctcttccccctcgtggcaggccatgcatgagcctcggacttttgctgtatatcttaacaacactggctacagaacagccttttttggaaaatacctcaatgaatataatggcagctacatcccccctgggtggcgagaatggcttggattaatcaagaattctcgcttctataattacactgtttgtcgcaatggcatcaaagaaaagcatggatttgattatgcaaaggactacttcacagacttaatcactaacgagagcattaattacttcaaaatgtctaagagaatgtatccccataggcccgttatgatggtgatcagccacgctgcgccccacggccccgaggactcagccccacagttttctaaactgtaccccaatgcttcccaacacataactcctagttataactatgcaccaaatatggataaacactggattatgcagtacacaggaccaatgctgcccatccacatggaatttacaaacattctacagcgcaaaaggctccagactttgatgtcagtggatgattctgtggagaggctgtataacatgctcgtggagacgggggagctggagaatacttacatcatttacaccgccgaccatggttaccatattgggcagtttggactggtcaaggggaaatccatgccatatgactttgatattcgtgtgcctttttttattcgtggtccaagtgtagaaccaggatcaatagtcccacagatcgttctcaacattgacttggcccccacgatcctggatattgctgggctcgacacacctcctgatgtggacggcaagtctgtcctcaaacttctggacccagaaaagccaggtaacaggtttcgaacaaacaagaaggccaaaatttggcgtgatacattcctagtggaaagaggcaaatttctacgtaagaaggaagaatccagcaagaatatccaacagtcaaatcacttgcccaaatatgaacgggtcaaagaactatgccagcaggccaggtaccagacagcctgtgaacaaccggggcagaagtggcaatgcattgaggatacatctggcaagcttcgaattcacaagtgtaaaggacccagtgacctgctcacagtccggcagagcacgcggaacctctacgctcgcggcttccatgacaaagacaaagagtgcagttgtagggagtctggttaccgtgccagcagaagccaaagaaagagtcaacggcaattcttgagaaaccaggggactccaaagtacaagcccagatttgtccatactcggcagacacgttccttgtccgtcgaatttgaaggtgaaatatatgacataaatctggaagaagaagaagaattgcaagtgttgcaaccaagaaacattgctaagcgtcatgatgaaggccacaaggggccaagagatctccaggcttccagtggtggcaacaggggcaggatgctggcagatagcagcaacgccgtgggcccacctaccactgtccgagtgacacacaagtgttttattcttcccaatgactctatccattgtgagagagaactgtaccaatcggccagagcgtggaaggaccataaggcatacattgacaaagagattgaagctctgcaagataaaattaagaatttaagagaagtgagaggacatctgaagagaaggaagcctgaggaatgtagctgcagtaaacaaagctattacaataaagagaaaggtgtaaaaaagcaagagaaattaaagagccatcttcacccattcaaggaggctgctcaggaagtagatagcaaactgcaacttttcaaggagaacaaccgtaggaggaagaaggagaggaaggagaagagacggcagaggaagggggaagagtgcagcctgcctggcctcacttgcttcacgcatgacaacaaccactggcagacagccccgttctggaacctgggatctttctgtgcttgcacgagttctaacaataacacctactggtgtttgcgtacagttaatgagacgcataattttcttttctgtgagtttgctactggctttttggagtattttgatatgaatacagatccttatcagctcacaaatacagtgcacacggtagaacgaggcattttgaatcagctacacgtacaactaatggagctcagaagctgtcaaggatataagcagtgcaacccaagacctaagaatcttgatgttggaaataaagatggaggaagctatgacctacacagaggacagttatgggatggatgggaaggttaatcagccccgtctcactgcagacatcaactggcaaggcctagaggagctacacagtgtgaatgaaaacatctatgagtacagacaaaactacagacttagtctggtggactggactaattacttgaaggatttagatagagtatttgcactgctgaagagtcactatgagcaaaataaaacaaataagactcaaactgctcaaagtgacgggttcttggttgtctctgctgagcacgctgtgtcaatggagatggcctctgctgactcagatgaagacccaaggcataaggttgggaaaacacctcatttgaccttgccagctgaccttcaaaccctgcatttgaaccgaccaacattaagtccagagagtaaacttgaatggaataacgacattccagaagttaatcatttgaattctgaacactggagaaaaaccgaaaaatggacggggcatgaagagactaatcatctggaaaccgatttcagtggcgatggcatgacagagctagagctcgggcccagccccaggctgcagcccattcgcaggcacccgaaagaacttccccagtatggtggtcctggaaaggacatttttgaagatcaactatatcttcctgtgcattccgatggaatttcagttcatcagatgttcaccatggccaccgcagaacaccgaagtaattccagcatagcggggaagatgttgaccaaggtggagaagaatcacgaaaaggagaagtcacagcacctagaaggcagcgcctcctcttcactctcctctgattagatgaaactgttaccttaccctaaacacagtatttctttttaacttttttatttgtaaactaataaaggtaatcacagccaccaacattccaagctaccctgggtacctttgtgcagtagaagctagtgagcatgtgagcaagcggtgtgcacacggagactcatcgttataatttactatctgccaagagtagaaagaaaggctggggatatttgggttggcttggttttgattttttgcttgtttgtttgttttgtactaaaacagtattatcttttgaatatcgtagggacataagtatatacatgttatccaatcaagatggctagaatggtgcctttctgagtgtctaaaacttgacacccctggtaaatctttcaacacacttccactgcctgcgtaatgaagttttgattcatttttaaccactggaatttttcaatgccgtcattttcagttagatgattttgcactttgagattaaaatgccatgtctatttgattagtcttatttttttatttttacaggcttatcagtctcactgttggctgtcattgtgacaaagtcaaataaacccccaaggacgacacacagtatggatcacatattgtttgacattaagcttttgccagaaaatgttgcatgtgttttacctcgacttgctaaaatcgattagcagaaaggcatggctaataatgttggtggtgaaaataaataaataagtaaacaaaatgaagattgcctgctctctctgtgcctagcctcaaagcgttcatcatacatcatacctttaagattgctatattttgggttattttcttgacaggagaaaaagatctaaagatcttttattttcatcttttttggttttcttggcatgactaagaagcttaaatgttgataaaatatgactagttttgaatttacaccaagaacttctcaataaaagaaaatcatgaatgctccacaatttcaacataccacaagagaagttaatttcttaacattgtgttctatgattatttgtaagaccttcaccaagttctgatatcttttaaagacatagttcaaaattgcttttgaaaatctgtattcttgaaaatatccttgttgtgtattaggtttttaaataccagctaaaggattacctcactgagtcatcagtaccctcctattcagctccccaagatgatgtgtttttgcttaccctaagagaggttttcttcttatttttagataattcaagtgcttagataaattatgttttctttaagtgtttatggtaaactcttttaaagaaaatttaatatgttatagctgaatctttttggtaactttaaatctttatcatagactctgtacatatgttcaaattagctgcttgcctgatgtgtgtatcatcggtgggatgacagaacaaacatatttatgatcatgaataatgtgctttgtaaaaagatttcaagttattaggaagcatactctgttttttaatcatgtataatattccatgatacttttatagaacaattctggcttcaggaaagtctagaagcaatatttcttcaaataaaaggtgtttaaacttt
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:23213 -> Molecular function: GO:0004065 [arylsulfatase activity] evidence: IDA
GeneID:23213 -> Molecular function: GO:0004065 [arylsulfatase activity] evidence: IMP
GeneID:23213 -> Molecular function: GO:0005509 [calcium ion binding] evidence: IEA
GeneID:23213 -> Molecular function: GO:0008449 [N-acetylglucosamine-6-sulfatase activity] evidence: IDA
GeneID:23213 -> Molecular function: GO:0008449 [N-acetylglucosamine-6-sulfatase activity] evidence: IMP
GeneID:23213 -> Biological process: GO:0001822 [kidney development] evidence: ISS
GeneID:23213 -> Biological process: GO:0001937 [negative regulation of endothelial cell proliferation] evidence: IDA
GeneID:23213 -> Biological process: GO:0002063 [chondrocyte development] evidence: ISS
GeneID:23213 -> Biological process: GO:0003094 [glomerular filtration] evidence: ISS
GeneID:23213 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:23213 -> Biological process: GO:0010575 [positive regulation vascular endothelial growth factor production] evidence: ISS
GeneID:23213 -> Biological process: GO:0014846 [esophagus smooth muscle contraction] evidence: ISS
GeneID:23213 -> Biological process: GO:0016525 [negative regulation of angiogenesis] evidence: IDA
GeneID:23213 -> Biological process: GO:0030177 [positive regulation of Wnt receptor signaling pathway] evidence: IDA
GeneID:23213 -> Biological process: GO:0030201 [heparan sulfate proteoglycan metabolic process] evidence: IDA
GeneID:23213 -> Biological process: GO:0030201 [heparan sulfate proteoglycan metabolic process] evidence: NAS
GeneID:23213 -> Biological process: GO:0030336 [negative regulation of cell migration] evidence: IMP
GeneID:23213 -> Biological process: GO:0030513 [positive regulation of BMP signaling pathway] evidence: IMP
GeneID:23213 -> Biological process: GO:0032836 [glomerular basement membrane development] evidence: ISS
GeneID:23213 -> Biological process: GO:0035860 [glial cell-derived neurotrophic factor receptor signaling pathway] evidence: ISS
GeneID:23213 -> Biological process: GO:0040036 [regulation of fibroblast growth factor receptor signaling pathway] evidence: IMP
GeneID:23213 -> Biological process: GO:0040037 [negative regulation of fibroblast growth factor receptor signaling pathway] evidence: IMP
GeneID:23213 -> Biological process: GO:0040037 [negative regulation of fibroblast growth factor receptor signaling pathway] evidence: ISS
GeneID:23213 -> Biological process: GO:0048010 [vascular endothelial growth factor receptor signaling pathway] evidence: IDA
GeneID:23213 -> Biological process: GO:0048706 [embryonic skeletal system development] evidence: ISS
GeneID:23213 -> Biological process: GO:0051216 [cartilage development] evidence: ISS
GeneID:23213 -> Biological process: GO:0060348 [bone development] evidence: ISS
GeneID:23213 -> Biological process: GO:0060384 [innervation] evidence: ISS
GeneID:23213 -> Biological process: GO:0060686 [negative regulation of prostatic bud formation] evidence: ISS
GeneID:23213 -> Cellular component: GO:0005615 [extracellular space] evidence: IDA
GeneID:23213 -> Cellular component: GO:0005615 [extracellular space] evidence: NAS
GeneID:23213 -> Cellular component: GO:0005783 [endoplasmic reticulum] evidence: IDA
GeneID:23213 -> Cellular component: GO:0005794 [Golgi apparatus] evidence: ISS
GeneID:23213 -> Cellular component: GO:0005795 [Golgi stack] evidence: IEA
GeneID:23213 -> Cellular component: GO:0005886 [plasma membrane] evidence: ISS
GeneID:23213 -> Cellular component: GO:0009986 [cell surface] evidence: IDA
GeneID:23213 -> Cellular component: GO:0045121 [membrane raft] evidence: IDA
by
@meso_cacase at
DBCLS
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