Home |
Help |
Advanced search
2024-05-02 07:07:08, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_015167 1834 bp mRNA linear PRI 12-MAY-2013
DEFINITION Homo sapiens jumonji domain containing 6 (JMJD6), transcript
variant 2, mRNA.
ACCESSION NM_015167
VERSION NM_015167.2 GI:125988388
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1834)
AUTHORS Unoki,M., Masuda,A., Dohmae,N., Arita,K., Yoshimatsu,M., Iwai,Y.,
Fukui,Y., Ueda,K., Hamamoto,R., Shirakawa,M., Sasaki,H. and
Nakamura,Y.
TITLE Lysyl 5-hydroxylation, a novel histone modification, by Jumonji
domain containing 6 (JMJD6)
JOURNAL J. Biol. Chem. 288 (9), 6053-6062 (2013)
PUBMED 23303181
REMARK GeneRIF: histones are additional substrates of JMJD6 in vivo.
Because 5-hydroxylation of lysyl residues inhibited N-acetylation
and N-methylation by an acetyltransferase and a methyltransferase
REFERENCE 2 (bases 1 to 1834)
AUTHORS Jansen,F., Yang,X., Hoyer,F.F., Paul,K., Heiermann,N., Becher,M.U.,
Abu Hussein,N., Kebschull,M., Bedorf,J., Franklin,B.S., Latz,E.,
Nickenig,G. and Werner,N.
TITLE Endothelial microparticle uptake in target cells is annexin
I/phosphatidylserine receptor dependent and prevents apoptosis
JOURNAL Arterioscler. Thromb. Vasc. Biol. 32 (8), 1925-1935 (2012)
PUBMED 22701020
REMARK GeneRIF: Endothelial microparticles are incorporated by endothelial
cells in an annexin I/phosphatidylserine receptor-dependent manner
and protect target cells against apoptosis.
REFERENCE 3 (bases 1 to 1834)
AUTHORS Han,G., Li,J., Wang,Y., Li,X., Mao,H., Liu,Y. and Chen,C.D.
TITLE The hydroxylation activity of Jmjd6 is required for its
homo-oligomerization
JOURNAL J. Cell. Biochem. 113 (5), 1663-1670 (2012)
PUBMED 22189873
REMARK GeneRIF: we did not detect arginine demethylase activity for Jmjd6,
but we did confirm that it could catalyze the lysyl-hydroxylation
of histone peptides
REFERENCE 4 (bases 1 to 1834)
AUTHORS Lee,Y.F., Miller,L.D., Chan,X.B., Black,M.A., Pang,B., Ong,C.W.,
Salto-Tellez,M., Liu,E.T. and Desai,K.V.
TITLE JMJD6 is a driver of cellular proliferation and motility and a
marker of poor prognosis in breast cancer
JOURNAL Breast Cancer Res. 14 (3), R85 (2012)
PUBMED 22621393
REMARK GeneRIF: data indicate JMJD6 has conserved functions and often
affects similar pathways across multiple cell types; it has ability
to promote cancer cell proliferation and motility; JMJD6 is a novel
biomarker of tumor aggressiveness with functional implications in
breast cancer growth and migration
Publication Status: Online-Only
REFERENCE 5 (bases 1 to 1834)
AUTHORS Klose,R.J., Kallin,E.M. and Zhang,Y.
TITLE JmjC-domain-containing proteins and histone demethylation
JOURNAL Nat. Rev. Genet. 7 (9), 715-727 (2006)
PUBMED 16983801
REFERENCE 6 (bases 1 to 1834)
AUTHORS Williamson,P. and Schlegel,R.A.
TITLE Hide and seek: the secret identity of the phosphatidylserine
receptor
JOURNAL J. Biol. 3 (4), 14 (2004)
PUBMED 15453906
REMARK Review article
REFERENCE 7 (bases 1 to 1834)
AUTHORS Chan,A., Seguin,R., Magnus,T., Papadimitriou,C., Toyka,K.V.,
Antel,J.P. and Gold,R.
TITLE Phagocytosis of apoptotic inflammatory cells by microglia and its
therapeutic implications: termination of CNS autoimmune
inflammation and modulation by interferon-beta
JOURNAL Glia 43 (3), 231-242 (2003)
PUBMED 12898702
REFERENCE 8 (bases 1 to 1834)
AUTHORS Ajmone-Cat,M.A., De Simone,R., Nicolini,A. and Minghetti,L.
TITLE Effects of phosphatidylserine on p38 mitogen activated protein
kinase, cyclic AMP responding element binding protein and nuclear
factor-kappaB activation in resting and activated microglial cells
JOURNAL J. Neurochem. 84 (2), 413-416 (2003)
PUBMED 12559004
REFERENCE 9 (bases 1 to 1834)
AUTHORS Vandivier,R.W., Fadok,V.A., Hoffmann,P.R., Bratton,D.L.,
Penvari,C., Brown,K.K., Brain,J.D., Accurso,F.J. and Henson,P.M.
TITLE Elastase-mediated phosphatidylserine receptor cleavage impairs
apoptotic cell clearance in cystic fibrosis and bronchiectasis
JOURNAL J. Clin. Invest. 109 (5), 661-670 (2002)
PUBMED 11877474
REMARK GeneRIF: Elastase-mediated phosphatidylserine receptor cleavage
impairs apoptotic cell clearance in cystic fibrosis and
bronchiectasis.
REFERENCE 10 (bases 1 to 1834)
AUTHORS Fadok,V.A., Bratton,D.L., Rose,D.M., Pearson,A., Ezekewitz,R.A. and
Henson,P.M.
TITLE A receptor for phosphatidylserine-specific clearance of apoptotic
cells
JOURNAL Nature 405 (6782), 85-90 (2000)
PUBMED 10811223
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DB451815.1, BC066654.1 and
AA226560.1.
On Feb 16, 2007 this sequence version replaced gi:23943859.
Summary: This gene encodes a nuclear protein with a JmjC domain.
JmjC domain-containing proteins are predicted to function as
protein hydroxylases or histone demethylases. This protein was
first identified as a putative phosphatidylserine receptor involved
in phagocytosis of apoptotic cells; however, subsequent studies
have indicated that it does not directly function in the clearance
of apoptotic cells, and questioned whether it is a true
phosphatidylserine receptor. Multiple transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq, Jul 2008].
Transcript Variant: This variant (2) uses an alternate splice site
in the 3' coding region and an alternate polyadenylation site,
compared to variant 1. The resulting protein (isoform 2) has a
shorter C-terminus, compared to isoform 1.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC047003.1, AK021780.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025098 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-318 DB451815.1 1-318
319-1808 BC066654.1 1-1490
1809-1834 AA226560.1 1-26 c
FEATURES Location/Qualifiers
source 1..1834
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17q25"
gene 1..1834
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/note="jumonji domain containing 6"
/db_xref="GeneID:23210"
/db_xref="HGNC:19355"
/db_xref="MIM:604914"
exon 1..453
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/inference="alignment:Splign:1.39.8"
variation complement(71)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370217771"
misc_feature 208..210
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/note="upstream in-frame stop codon"
variation complement(233)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="g"
/db_xref="dbSNP:371235798"
variation complement(254)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:76209526"
variation complement(297)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:375435405"
variation complement(318)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200707910"
CDS 325..1536
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/EC_number="1.14.11.-"
/note="isoform 2 is encoded by transcript variant 2;
phosphatidylserine receptor; bifunctional arginine
demethylase and lysyl-hydroxylase JMJD6; jmjC
domain-containing protein 6; histone arginine demethylase
JMJD6; peptide-lysine 5-dioxygenase JMJD6; jumonji
domain-containing protein 6"
/codon_start=1
/product="bifunctional arginine demethylase and
lysyl-hydroxylase JMJD6 isoform 2"
/protein_id="NP_055982.2"
/db_xref="GI:125988389"
/db_xref="CCDS:CCDS42384.1"
/db_xref="GeneID:23210"
/db_xref="HGNC:19355"
/db_xref="MIM:604914"
/translation="
MNHKSKKRIREAKRSARPELKDSLDWTRHNYYESFSLSPAAVADNVERADALQLSVEEFVERYERPYKPVVLLNAQEGWSAQEKWTLERLKRKYRNQKFKCGEDNDGYSVKMKMKYYIEYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQGHKRWCLFPTSTPRELIKVTRDEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHKTVRGRPKLSRKWYRILKQEHPELAVLADSVDLQESTGIASDSSSDSSSSSSSSSSDSDSECESGSEGDGTVHRRKKRRTCSMVGNGDTTSQDDCVSKERSSSR
"
misc_feature 340..354
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q6NYC1.1);
Region: Nuclear localization signal 1"
misc_feature 595..609
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q6NYC1.1);
Region: Nuclear localization signal 2"
misc_feature 745..759
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q6NYC1.1);
Region: Nuclear localization signal 3"
misc_feature 823..834
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q6NYC1.1);
Region: Nuclear localization signal 4"
misc_feature 844..1188
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/note="JmjC domain, hydroxylase; Region: JmjC; pfam02373"
/db_xref="CDD:202224"
misc_feature 1441..1458
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q6NYC1.1);
Region: Nuclear localization signal 5"
variation complement(336)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:368575248"
variation complement(368)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201990497"
variation complement(429)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:372892599"
exon 454..842
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/inference="alignment:Splign:1.39.8"
variation complement(470)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="c"
/db_xref="dbSNP:367636744"
variation complement(508)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="c"
/db_xref="dbSNP:373501787"
variation complement(510)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:375036353"
variation complement(512)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370497426"
variation complement(532)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="g"
/db_xref="dbSNP:377176647"
variation complement(567)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:374194292"
variation complement(585)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:371247103"
variation complement(594)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:376815189"
variation complement(606)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:373361850"
variation complement(710)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:369981508"
variation complement(711)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:375672370"
variation complement(718)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:372553878"
variation complement(756)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369150283"
variation complement(764)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:376208302"
variation complement(780)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:199836423"
variation complement(801)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200613423"
variation complement(840)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370535475"
exon 843..1129
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/inference="alignment:Splign:1.39.8"
variation complement(891)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:35609518"
variation complement(972)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="t"
/db_xref="dbSNP:374662446"
variation complement(982)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370584612"
variation complement(1000)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:377330827"
variation complement(1048)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:374399276"
variation complement(1061)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370913824"
variation complement(1099)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="c"
/db_xref="dbSNP:140945471"
exon 1130..1265
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/inference="alignment:Splign:1.39.8"
variation complement(1158)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="g"
/db_xref="dbSNP:376293253"
variation complement(1160)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:373296913"
variation complement(1170)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:181727223"
variation complement(1201)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:144947109"
exon 1266..1404
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/inference="alignment:Splign:1.39.8"
variation complement(1276)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:367626052"
variation complement(1302)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:375092056"
variation complement(1345)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:372069555"
variation complement(1392)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="g"
/db_xref="dbSNP:368092175"
variation complement(1395)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:192242816"
variation complement(1396)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:200644127"
exon 1405..1823
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/inference="alignment:Splign:1.39.8"
variation complement(1407)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:192248986"
variation complement(1426)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:372708038"
variation complement(1451)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370575056"
variation complement(1460)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:377582812"
variation complement(1461)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="g"
/replace="t"
/db_xref="dbSNP:188024492"
variation complement(1479)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:372217669"
variation complement(1500)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:149210415"
variation complement(1548)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200775031"
variation complement(1573)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:374027972"
variation complement(1576)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369523617"
variation complement(1577)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="g"
/replace="t"
/db_xref="dbSNP:377124451"
variation complement(1582)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="g"
/replace="t"
/db_xref="dbSNP:201523447"
variation complement(1583)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="g"
/replace="t"
/db_xref="dbSNP:373899686"
variation complement(1674)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="c"
/replace="t"
/db_xref="dbSNP:182956775"
variation complement(1731)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:145394703"
variation complement(1751)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:190524184"
variation complement(1784)
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
/replace="a"
/replace="g"
/db_xref="dbSNP:72874673"
polyA_signal 1791..1796
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
polyA_site 1823
/gene="JMJD6"
/gene_synonym="PSR; PTDSR; PTDSR1"
ORIGIN
ggggcggggcggtgacgcagccgacgtgaccttcccaacatggcggaggcccgccgtatgtgaaggagtaccccaggggagccaaagccaatggaaaaccgcgagaggcgtcggggcggggaagacggcggccgcttgcccaacccgaggctcgggaggtggctggggagtgaattttctggaaggcgactttaaaggcgccgggactgagcgaagggcgtttgggtactgccgtcgccgccgcccaggccggggaggggtgcgttagtgtcaggaagcgggctgcgccgaggtcgtagcggaaccagctggcgaccccgcagaatgaaccacaagagcaagaagcgcatccgcgaggccaagcggagtgcgcggccggagctcaaggactcgctggattggacccggcacaactactacgagagcttctcgctgagcccggcggccgtggcggataacgtggaaagggcagatgctttacagctgtctgtggaagaatttgtggagcggtatgaaagaccttacaagcccgtggttttgttgaatgcgcaagagggctggtctgcgcaggagaaatggactctggagcgcctaaaaaggaaatatcggaaccagaagttcaagtgtggtgaggataacgatggctactcagtgaagatgaagatgaaatactacatcgagtacatggagagcactcgagatgatagtcccctttacatctttgacagcagctatggtgaacaccctaaaagaaggaaacttttggaagactacaaggtgccaaagtttttcactgatgaccttttccagtatgctggggagaagcgcaggcccccttacaggtggtttgtgatggggccaccacgctccggaactgggattcacatcgaccctctgggaaccagtgcctggaatgccttagttcagggccacaagcgctggtgcctgtttcctaccagcactcccagggaactcatcaaagtgacccgagacgaaggagggaaccagcaagacgaagctattacctggtttaatgttatttatccccggacacagcttccaacctggccacctgaattcaaacccctggaaatcttacaaaaaccaggagagactgtctttgtaccaggaggctggtggcatgttgtcctcaatctcgacactactatcgccatcacccaaaattttgccagcagcaccaacttccctgtggtatggcacaagacggtaagagggagaccaaagttatcaaggaaatggtataggattttgaagcaagagcaccccgagttggcagtcctcgcagactcggttgaccttcaggagtccacagggatagcttccgacagctccagcgactcttccagctcctccagctccagttcgtcagactccgactcagagtgcgagtctggatccgagggcgatgggacagtgcaccgcaggaagaagaggaggacgtgcagcatggtgggaaacggggacaccacctcccaggacgactgtgtcagcaaagagcgcagctcctccaggtgacccagcaaggctgttgtctgtatggaaggacacgctcgcggcaagggcagggcctggggagggtggcctgtccagtcctgcagacaaggggaggcctgacagagcccaagaatgaggacaccctcggcacgggaacccattcacttagcgtttgctccagtagctttccctctgctaccaatgcagataaacgcggcttgttttactcaggcaagagaatgtgaatagtgccaagaaaatcctttacattatttaataaaaattgaatccattttctatcttggaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:23210 -> Molecular function: GO:0003723 [RNA binding] evidence: TAS
GeneID:23210 -> Molecular function: GO:0003727 [single-stranded RNA binding] evidence: IDA
GeneID:23210 -> Molecular function: GO:0004872 [receptor activity] evidence: IEA
GeneID:23210 -> Molecular function: GO:0005506 [iron ion binding] evidence: IDA
GeneID:23210 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:23210 -> Molecular function: GO:0016702 [oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen] evidence: IEA
GeneID:23210 -> Molecular function: GO:0033746 [histone demethylase activity (H3-R2 specific)] evidence: IDA
GeneID:23210 -> Molecular function: GO:0033749 [histone demethylase activity (H4-R3 specific)] evidence: IDA
GeneID:23210 -> Molecular function: GO:0042802 [identical protein binding] evidence: IDA
GeneID:23210 -> Molecular function: GO:0070815 [peptidyl-lysine 5-dioxygenase activity] evidence: IDA
GeneID:23210 -> Biological process: GO:0001822 [kidney development] evidence: IEA
GeneID:23210 -> Biological process: GO:0002040 [sprouting angiogenesis] evidence: ISS
GeneID:23210 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
GeneID:23210 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: IEA
GeneID:23210 -> Biological process: GO:0006397 [mRNA processing] evidence: IEA
GeneID:23210 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:23210 -> Biological process: GO:0007166 [cell surface receptor signaling pathway] evidence: IEA
GeneID:23210 -> Biological process: GO:0007507 [heart development] evidence: IEA
GeneID:23210 -> Biological process: GO:0008380 [RNA splicing] evidence: IEA
GeneID:23210 -> Biological process: GO:0018395 [peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine] evidence: IDA
GeneID:23210 -> Biological process: GO:0030324 [lung development] evidence: IEA
GeneID:23210 -> Biological process: GO:0033077 [T cell differentiation in thymus] evidence: IEA
GeneID:23210 -> Biological process: GO:0042116 [macrophage activation] evidence: IEA
GeneID:23210 -> Biological process: GO:0043654 [recognition of apoptotic cell] evidence: IEA
GeneID:23210 -> Biological process: GO:0048024 [regulation of mRNA splicing, via spliceosome] evidence: IMP
GeneID:23210 -> Biological process: GO:0048821 [erythrocyte development] evidence: IEA
GeneID:23210 -> Biological process: GO:0060041 [retina development in camera-type eye] evidence: IEA
GeneID:23210 -> Biological process: GO:0070078 [histone H3-R2 demethylation] evidence: IDA
GeneID:23210 -> Biological process: GO:0070079 [histone H4-R3 demethylation] evidence: IDA
GeneID:23210 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:23210 -> Cellular component: GO:0005654 [nucleoplasm] evidence: IDA
GeneID:23210 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
GeneID:23210 -> Cellular component: GO:0005886 [plasma membrane] evidence: IEA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_055982 -> EC 1.14.11.-
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.