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2024-03-28 19:31:56, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_014646               6245 bp    mRNA    linear   PRI 10-JUL-2013
DEFINITION  Homo sapiens lipin 2 (LPIN2), mRNA.
ACCESSION   NM_014646
VERSION     NM_014646.2  GI:22027649
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6245)
  AUTHORS   Herlin T, Fiirgaard B, Bjerre M, Kerndrup G, Hasle H, Bing X and
            Ferguson PJ.
  TITLE     Efficacy of anti-IL-1 treatment in Majeed syndrome
  JOURNAL   Ann. Rheum. Dis. 72 (3), 410-413 (2013)
   PUBMED   23087183
  REMARK    GeneRIF: We describe two brothers with Majeed syndrome, homozygous
            novel 2-base pair deletion in LPIN2 (c.1312_1313delCT;
            p.Leu438fs+16X)
REFERENCE   2  (bases 1 to 6245)
  AUTHORS   Michot C, Hubert L, Romero NB, Gouda A, Mamoune A, Mathew S, Kirk
            E, Viollet L, Rahman S, Bekri S, Peters H, McGill J, Glamuzina E,
            Farrar M, von der Hagen M, Alexander IE, Kirmse B, Barth M, Laforet
            P, Benlian P, Munnich A, JeanPierre M, Elpeleg O, Pines O,
            Delahodde A, de Keyzer Y and de Lonlay P.
  TITLE     Study of LPIN1, LPIN2 and LPIN3 in rhabdomyolysis and
            exercise-induced myalgia
  JOURNAL   J. Inherit. Metab. Dis. 35 (6), 1119-1128 (2012)
   PUBMED   22481384
  REMARK    GeneRIF: LPIN1-related myolysis constitutes a major cause of
            early-onset rhabdomyolysis and occasionally in adults. Heterozygous
            LPIN1 mutations may cause mild muscular symptoms. No major defects
            of LPIN2 or LPIN3 genes were associated with muscle manifestations.
REFERENCE   3  (bases 1 to 6245)
  AUTHORS   Valdearcos M, Esquinas E, Meana C, Pena L, Gil-de-Gomez L, Balsinde
            J and Balboa MA.
  TITLE     Lipin-2 reduces proinflammatory signaling induced by saturated
            fatty acids in macrophages
  JOURNAL   J. Biol. Chem. 287 (14), 10894-10904 (2012)
   PUBMED   22334674
  REMARK    GeneRIF: role of lipin-2 in the proinflammatory action of saturated
            fatty acids in murine and human macrophages
REFERENCE   4  (bases 1 to 6245)
  AUTHORS   Sim X, Ong RT, Suo C, Tay WT, Liu J, Ng DP, Boehnke M, Chia KS,
            Wong TY, Seielstad M, Teo YY and Tai ES.
  TITLE     Transferability of type 2 diabetes implicated loci in multi-ethnic
            cohorts from Southeast Asia
  JOURNAL   PLoS Genet. 7 (4), E1001363 (2011)
   PUBMED   21490949
REFERENCE   5  (bases 1 to 6245)
  AUTHORS   Liu GH, Qu J, Carmack AE, Kim HB, Chen C, Ren H, Morris AJ, Finck
            BN and Harris TE.
  TITLE     Lipin proteins form homo- and hetero-oligomers
  JOURNAL   Biochem. J. 432 (1), 65-76 (2010)
   PUBMED   20735359
  REMARK    GeneRIF: Data revealed that lipin 1 formed stable homo-oligomers
            with itself and hetero-oligomers with lipin 2/3.
REFERENCE   6  (bases 1 to 6245)
  AUTHORS   Aulchenko YS, Pullen J, Kloosterman WP, Yazdanpanah M, Hofman A,
            Vaessen N, Snijders PJ, Zubakov D, Mackay I, Olavesen M, Sidhu B,
            Smith VE, Carey A, Berezikov E, Uitterlinden AG, Plasterk RH,
            Oostra BA and van Duijn CM.
  TITLE     LPIN2 is associated with type 2 diabetes, glucose metabolism, and
            body composition
  JOURNAL   Diabetes 56 (12), 3020-3026 (2007)
   PUBMED   17804763
  REMARK    GeneRIF: A single nucleotide polymorphism of the LPIN2 gene is
            associated with type 2 diabetes and fat distribution.
            GeneRIF: Observational study of gene-disease association and
            gene-environment interaction. (HuGE Navigator)
REFERENCE   7  (bases 1 to 6245)
  AUTHORS   Ferguson PJ, Chen S, Tayeh MK, Ochoa L, Leal SM, Pelet A, Munnich
            A, Lyonnet S, Majeed HA and El-Shanti H.
  TITLE     Homozygous mutations in LPIN2 are responsible for the syndrome of
            chronic recurrent multifocal osteomyelitis and congenital
            dyserythropoietic anaemia (Majeed syndrome)
  JOURNAL   J. Med. Genet. 42 (7), 551-557 (2005)
   PUBMED   15994876
  REMARK    GeneRIF: We conclude that homozygous mutations in LPIN2 result in
            Majeed syndrome. Understanding the aberrant immune response in this
            condition will shed light on the aetiology of other inflammatory
            disorders of multifactorial aetiology
REFERENCE   8  (bases 1 to 6245)
  AUTHORS   Zhou J and Young TL.
  TITLE     Evaluation of Lipin 2 as a candidate gene for autosomal dominant 1
            high-grade myopia
  JOURNAL   Gene 352, 10-19 (2005)
   PUBMED   15862761
  REMARK    GeneRIF: LPIN2 gene was excluded as a candidate for myopia 2
            (MYP2), but the SNPs detected in this study will aid in future
            mapping and association studies involving this gene.
REFERENCE   9  (bases 1 to 6245)
  AUTHORS   Peterfy M, Phan J, Xu P and Reue K.
  TITLE     Lipodystrophy in the fld mouse results from mutation of a new gene
            encoding a nuclear protein, lipin
  JOURNAL   Nat. Genet. 27 (1), 121-124 (2001)
   PUBMED   11138012
REFERENCE   10 (bases 1 to 6245)
  AUTHORS   Lehner R and Kuksis A.
  TITLE     Biosynthesis of triacylglycerols
  JOURNAL   Prog. Lipid Res. 35 (2), 169-201 (1996)
   PUBMED   8944226
  REMARK    Review article
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC152448.1, AP000919.6 and
            BQ014306.1.
            On Jul 31, 2002 this sequence version replaced gi:7662021.
            
            Summary: Mouse studies suggest that this gene functions during
            normal adipose tissue development and may play a role in human
            triglyceride metabolism. This gene represents a candidate gene for
            human lipodystrophy, characterized by loss of body fat, fatty
            liver, hypertriglyceridemia, and insulin resistance. [provided by
            RefSeq, Jul 2008].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC152448.1, D87436.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           ERS025081, ERS025082 [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2932              BC152448.1         1-2932
            2933-6069           AP000919.6         98438-101574        c
            6070-6245           BQ014306.1         1-176               c
FEATURES             Location/Qualifiers
     source          1..6245
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="18"
                     /map="18p11.31"
     gene            1..6245
                     /gene="LPIN2"
                     /note="lipin 2"
                     /db_xref="GeneID:9663"
                     /db_xref="HGNC:14450"
                     /db_xref="HPRD:16114"
                     /db_xref="MIM:605519"
     exon            1..230
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    219..221
                     /gene="LPIN2"
                     /note="upstream in-frame stop codon"
     exon            231..431
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     CDS             240..2930
                     /gene="LPIN2"
                     /EC_number="3.1.3.4"
                     /note="lipin-2"
                     /codon_start=1
                     /product="phosphatidate phosphatase LPIN2"
                     /protein_id="NP_055461.1"
                     /db_xref="GI:7662022"
                     /db_xref="CCDS:CCDS11829.1"
                     /db_xref="GeneID:9663"
                     /db_xref="HGNC:14450"
                     /db_xref="HPRD:16114"
                     /db_xref="MIM:605519"
                     /translation="
MNYVGQLAGQVIVTVKELYKGINQATLSGCIDVIVVQQQDGSYQCSPFHVRFGKLGVLRSKEKVIDIEINGSAVDLHMKLGDNGEAFFVEETEEEYEKLPAYLATSPIPTEDQFFKDIDTPLVKSGGDETPSQSSDISHVLETETIFTPSSVKKKKRRRKKYKQDSKKEEQAASAAAEDTCDVGVSSDDDKGAQAARGSSNASLKEEECKEPLLFHSGDHYPLSDGDWSPLETTYPQTACPKSDSELEVKPAESLLRSESHMEWTWGGFPESTKVSKRERSDHHPRTATITPSENTHFRVIPSEDNLISEVEKDASMEDTVCTIVKPKPRALGTQMSDPTSVAELLEPPLESTQISSMLDADHLPNAALAEAPSESKPAAKVDSPSKKKGVHKRSQHQGPDDIYLDDLKGLEPEVAALYFPKSESEPGSRQWPESDTLSGSQSPQSVGSAAADSGTECLSDSAMDLPDVTLSLCGGLSENGEISKEKFMEHIITYHEFAENPGLIDNPNLVIRIYNRYYNWALAAPMILSLQVFQKSLPKATVESWVKDKMPKKSGRWWFWRKRESMTKQLPESKEGKSEAPPASDLPSSSKEPAGARPAENDSSSDEGSQELEESITVDPIPTEPLSHGSTTSYKKSLRLSSDQIAKLKLHDGPNDVVFSITTQYQGTCRCAGTIYLWNWNDKIIISDIDGTITKSDALGQILPQLGKDWTHQGIAKLYHSINENGYKFLYCSARAIGMADMTRGYLHWVNDKGTILPRGPLMLSPSSLFSAFHREVIEKKPEKFKIECLNDIKNLFAPSKQPFYAAFGNRPNDVYAYTQVGVPDCRIFTVNPKGELIQERTKGNKSSYHRLSELVEHVFPLLSKEQNSAFPCPEFSSFCYWRDPIPEVDLDDLS
"
     misc_feature    240..581
                     /gene="LPIN2"
                     /note="lipin, N-terminal conserved region; Region:
                     Lipin_N; pfam04571"
                     /db_xref="CDD:113346"
     misc_feature    240..563
                     /gene="LPIN2"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q92539.1);
                     Region: N-LIP"
     misc_feature    696..713
                     /gene="LPIN2"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q92539.1);
                     Region: Nuclear localization signal (Potential)"
     misc_feature    966..968
                     /gene="LPIN2"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    2142..2750
                     /gene="LPIN2"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q92539.1);
                     Region: C-LIP"
     misc_feature    2292..2762
                     /gene="LPIN2"
                     /note="This domain is found in Saccharomyces cerevisiae
                     protein SMP2, proteins with an N-terminal lipin domain and
                     phosphatidylinositol transfer proteins; Region: LNS2;
                     smart00775"
                     /db_xref="CDD:197870"
     misc_feature    2292..2762
                     /gene="LPIN2"
                     /note="LNS2 (Lipin/Ned1/Smp2); Region: LNS2; pfam08235"
                     /db_xref="CDD:149348"
     misc_feature    2304..2318
                     /gene="LPIN2"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q92539.1);
                     Region: DXDXT motif"
     misc_feature    2337..2351
                     /gene="LPIN2"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q92539.1);
                     Region: LXXIL motif"
     exon            432..527
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     exon            528..829
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     exon            830..937
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     exon            938..1061
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     exon            1062..1407
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     exon            1408..1507
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     exon            1508..1695
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     variation       1649
                     /gene="LPIN2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35932462"
     exon            1696..1789
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     exon            1790..1859
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     exon            1860..1949
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     exon            1950..2032
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     exon            2033..2177
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     exon            2178..2326
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     exon            2327..2413
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     exon            2414..2566
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     exon            2567..2681
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     exon            2682..2785
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     exon            2786..6229
                     /gene="LPIN2"
                     /inference="alignment:Splign:1.39.8"
     variation       2933
                     /gene="LPIN2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3745012"
     variation       3615
                     /gene="LPIN2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:607549"
     variation       3727
                     /gene="LPIN2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:3810064"
     variation       3877..3878
                     /gene="LPIN2"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:3840906"
     variation       3880
                     /gene="LPIN2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:3810065"
     STS             4088..4189
                     /gene="LPIN2"
                     /standard_name="A006I48"
                     /db_xref="UniSTS:54966"
     STS             4773..5086
                     /gene="LPIN2"
                     /standard_name="SHGC-82401"
                     /db_xref="UniSTS:104544"
     variation       4900
                     /gene="LPIN2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:13286"
     STS             4918..5836
                     /gene="LPIN2"
                     /standard_name="LPIN2_8975"
                     /db_xref="UniSTS:468080"
     STS             5037..5161
                     /gene="LPIN2"
                     /standard_name="RH46193"
                     /db_xref="UniSTS:39071"
     variation       5192
                     /gene="LPIN2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1803421"
     STS             5469..5617
                     /gene="LPIN2"
                     /standard_name="WI-15441"
                     /db_xref="UniSTS:78278"
     variation       5853
                     /gene="LPIN2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202079191"
     variation       5876
                     /gene="LPIN2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:4781"
     STS             5918..6189
                     /gene="LPIN2"
                     /standard_name="G60225"
                     /db_xref="UniSTS:137336"
     STS             5934..6118
                     /gene="LPIN2"
                     /standard_name="WIAF-1505"
                     /db_xref="UniSTS:56326"
     variation       5938
                     /gene="LPIN2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:10937"
     variation       5945
                     /gene="LPIN2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:14916"
     STS             5977..6160
                     /gene="LPIN2"
                     /standard_name="RH8145"
                     /db_xref="UniSTS:92218"
     STS             5990..6161
                     /gene="LPIN2"
                     /standard_name="WIAF-2076"
                     /db_xref="UniSTS:20577"
     variation       5998
                     /gene="LPIN2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1985"
     STS             6042..6192
                     /gene="LPIN2"
                     /standard_name="HSC1YH092"
                     /db_xref="UniSTS:80896"
     variation       6069
                     /gene="LPIN2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1164"
     variation       6194
                     /gene="LPIN2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1803420"
     polyA_signal    6204..6209
                     /gene="LPIN2"
     polyA_site      6229
                     /gene="LPIN2"
ORIGIN      
gagaagaagtggcaggtgatgctgaagcgggggagaagcggcagagccggccacacagtgcaggggatggagacaggtgctgggctggtcctcctgcagcatcctcagttgttggagggcagtcatcctcaggccgtacccagccagagaagaaaaagaacagtgtgaagccacgtgtgatagccgtccaacatcggctcttccctccaattacattgtagttgattgtgtctcaaaccatgaattatgtgggacagctggctgggcaggtgattgtcactgtgaaggaactctacaagggcattaaccaggccaccctctctgggtgcattgatgtcatcgtggtacagcagcaggatggcagctatcagtgttcaccttttcacgttcggtttggaaagctgggagtcctgagatccaaagagaaagtgattgatatagaaatcaacggcagtgcagtggatcttcacatgaagttgggtgataacggagaagctttctttgttgaggagactgaagaagaatatgaaaagcttcctgcttaccttgccacctcaccaattcctactgaagatcagttctttaaagatattgacacccctttggtgaaatcgggtggagatgaaacaccatctcagagttcagacatctcacacgtcttggaaacagagacaatttttactccaagttctgtgaaaaagaaaaaacgaaggagaaagaaatacaaacaggacagtaagaaggaagagcaggccgcatctgctgctgcagaagacacatgtgatgtaggcgtgagctccgatgatgacaagggggcccaggcagcacgaggatcttcaaatgcttccttgaaagaagaagaatgtaaagagcctttgctcttccattctggggatcattaccccttatctgatggagattggtcccctttagagaccacctatccccagacagcgtgtcctaagagtgattcagagctggaggtgaaacctgcggagagcctgctcagatcagagtctcacatggagtggacgtggggcggattcccagagtccaccaaggtcagcaaaagagaacgatctgaccatcatcctaggacagctacaattacaccatcagaaaatactcattttcgggtaattcccagtgaggacaacctcatcagtgaagttgagaaggatgcttccatggaagacactgtctgtaccatagtgaagcccaaacccagagccctgggtacacagatgagcgacccaacatctgtggcagagcttctcgaacctcctcttgagagtactcagatttcatctatgttagatgctgaccaccttcccaacgcagccttagcggaggcgccctcagaatccaaaccggcagctaaagtagactcgccgtcaaagaagaaaggtgttcacaaaagaagccaacaccagggacctgatgatatttaccttgatgacttaaagggtctagaacctgaagttgcagctctttatttccctaaaagtgaatcggagcccggttccaggcagtggcccgagtctgacacactctctggctcccagtccccacagtccgtgggaagcgcagctgcagatagcggcaccgagtgcctctcagattctgccatggacttgcctgacgttaccctctccctttgcgggggcctcagtgaaaatggagaaatttcaaaagaaaaattcatggagcatatcattacttatcacgaatttgcagaaaaccctggacttatagacaatcctaaccttgtaataaggatatataatcgttactataactgggctttggcagctcccatgatccttagcttgcaagtattccagaagagcttgcctaaggccacagttgagtcctgggtgaaagacaagatgccaaagaaatctggtcgctggtggttttggcgaaagagagaaagcatgaccaaacagctgccagaatccaaggagggaaaatctgaggcaccgccagccagtgacctgccatccagctccaaggagccggccggtgccaggccggccgagaatgactcctcgagtgacgagggatcacaggagctcgaagaatccatcacagtggaccccatccccacagagcccctgagccacggcagcacaacttcatataagaagtctctccgcctctcctcagaccagatcgcaaaactgaagctccacgatggcccaaatgatgttgtgtttagtattacaacccagtatcaaggcacctgtcgctgtgcagggaccatttacctgtggaactggaatgacaagatcatcatttctgatattgatgggacaataaccaagtcggatgctttgggacagattctcccacagctgggcaaagactggacccaccagggtatagcaaagctctaccattccatcaatgagaatggctacaagtttctgtactgctcggctcgtgccatcggcatggccgacatgacccgtggctacctgcactgggtcaatgacaagggcacaatcttgccccggggccccctgatgctgtcccccagcagcttgttctccgccttccacagagaagtgatagaaaagaaaccagagaagttcaaaattgagtgtctaaatgatatcaagaatctgtttgccccgtctaagcagcccttctatgctgcctttggaaaccgtccaaatgatgtctatgcctacacacaagttggagttccagactgtagaatattcaccgtgaaccccaagggtgaattaatacaagaaagaaccaaaggaaacaagtcatcgtatcacaggctgagtgagctcgtggagcatgtgttcccccttctcagtaaggagcagaattccgcttttccctgcccggagttcagctccttctgctactggcgagacccgatccctgaagtggacctggatgacctgtcttgaggcggcacctcagtgggtgggcagggcttggtccccctccccacagcaagggaaggcagctggctcttctgctgacctcagataccagccttccccagcggggacgggtgcttctggagctggtcccgccatcctcctttgccttcccaggccagctgctcaggctcggcaggtctgcagctcagctcctggaaggagaagggaggaactgggcctggggctggaggcctgggatccctcctttgtgggtcgcacacatgtttcctgctgtgagctggggcctccttccattgcatcattttaaaggaagaaaaaagcagctaaaaaagagtggaccaaaacactgcacacagtgaagtgttccagtttccactgggcagttgaggtggcttctgtaaccagggctgtcttcagatgtcagggtccctgaactgctgcgggcccagtcagtgatgctggctgaagctgcctgtgcacgtttcttctctggtcgcctcatttcctgctacactgaaggggtcagctgctccagtgggccaagttgggcaggacccccgcccctgcagggcccatgcaccagagccactgagcccagtcccataaacctggccctctttggggaaagatccccacagagcatcctcctctcatctgtgacaactccacgagcccttaatttcttagtcctcaccagaagaacaggtctcacaagtatatatttgatgtctgtaataaaagtgggaaggtgggtcttaaaacagaccaaaccccgccccgcccccaacaactctgcttttagggaggcctccgaaatgcagataggcggttgagtggggtcctgggaagagcgctgaatccctctgcttgctgcctggtgtgggcctttggaaagcatcttgccttgggacaggatttctaaaattctgtgattcagatttgtcagggaagcacagtgaagcttgcttaaaggcactggccagcagtgtgtgactttggcttttgggatcacaccctgtaatcgggcccgtggaagcagcgtcaaagaggggtcttggagctcctatggagcagactgccccccgagcagtgtccccagcctagccctgtgagaccccatggggacacgggtgcctatgtattttcactaaaatatacatggtagctccatttactgatgcggttgtaatgagctcacatcgtgtctgaagagatggcaccagggaaaggtgtgccataagctgctccagagcttttggtatgctgagtgttgacagagctgcactcttaacatcaagagaactgtcaggagcccagaaccaaccccaggtcttggtctccattggcgagaacacaggacgtggtggttcctgagcagagagggatctgcagatacaggcttggcgctcggggtggtctcgtggccaactcttcatgcccctgccgttgtagtggaacctctacatgttttagtttgcttcacctaaaataatgctgatctagagatagagaaataggggtggttatttttccagattggagagttgaaagtccctgactgatttcagccattttcctagtgcttgtcggatgcagagacaatgttgaaatcccctaaacacagttctcagtggcaaaacctaggaaggctcatgttcccagagaagggaccacatgagccttctcccatgcaaagcttcccccagcttaaatagttgataaggactaattgtttaatgagtttatttatctacagtaggttagggatcctgggttctgtttatatgaagttcttcccagtttgtgaattctagtacagcagccatgcagccaccttatttcatagatgccatctgtgtgtcctcttgactaccttctatttagaggaagaatgagagctttgtgtgtttaactgagcttatagtaggacttctttgcatatgtatggtactgaaaaatcttaatatacatctttaatcctttttaggttgtcctttaaagagtttttgactagtttctttttcttgacagctcttctctttggacacatgggccttcttagagggttcagtctaggacccggctctcctggccctgtgttgagggtagctggtccctctgtccctgtgtctgctagcactagactttgttgctgcagattgatccagtgggtacataggctaattaatgtgagtctttttccttgtttaaaggagtccctcttgctgaaagtagatgattactattgctgtagtgttaggaaagtattaagtttgtgctgaaaatccattgccatttggtacaaatgacatttgttctttctgtgaaagagatgccctcgagtgtgtttgtacacaaacccttaggatggtgagttgaagcatcaccctcgcgctatcttcagtgacgggtgacggctcagggagatggcaggcagattgggctctaagtcattattctctcagttactccattggtgaaatggccctttccctctttgcagttcagtctaagtctcgtatttgctttgctgtctgtgtgctgaagctcgtcccgtgtgagttgctgtctgccccttgtcaggctgtgaggtgctcgtgtagacctggagcatgcaggctgcctccgtttttgggtactgtgttgtgttttgctctgtctaaaaacatctgcatagttttcaactggaaaaagaaaaaacttaaaaatgggatgtcctaaaatgaaagctgctcaaagtcacagaacaaccgagggacaaaggagattggatgactgggaagcgctggcccggaacagcccctgcaactgtggggcctgcacacagcccttccacagttggcactgcaggtgcaggccaaccctttaaagaataaacaaggaagtcagctctttcactttttacaagttggcaaaaacagacttccggggaatttcgatgttttcccgtgttgtagagcttccagggtttaataaaactggttaaaaattgagtctttccctgaagtaagtgctctttccagatgaaaactactcttttggttttgtttgaaagtaagaaagggaggggaaactttgctcttttaataattatgttcagcctatgatgaagtatttgattattagacagcaatgtcactaataagttttaagttgtccaaagttaattgtaaacatcatcagtacagtactcttagttacagtaaagcaattgttgcaagatgaatggctaatattttggtgcagtgtttgatgttcaaaacaaaatgttacaacaataaacgaacataacataaactgaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:9663 -> Molecular function: GO:0003713 [transcription coactivator activity] evidence: ISS
            GeneID:9663 -> Molecular function: GO:0008195 [phosphatidate phosphatase activity] evidence: ISS
            GeneID:9663 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
            GeneID:9663 -> Biological process: GO:0006629 [lipid metabolic process] evidence: ISS
            GeneID:9663 -> Biological process: GO:0006631 [fatty acid metabolic process] evidence: IEA
            GeneID:9663 -> Biological process: GO:0006644 [phospholipid metabolic process] evidence: TAS
            GeneID:9663 -> Biological process: GO:0006646 [phosphatidylethanolamine biosynthetic process] evidence: TAS
            GeneID:9663 -> Biological process: GO:0006656 [phosphatidylcholine biosynthetic process] evidence: TAS
            GeneID:9663 -> Biological process: GO:0019432 [triglyceride biosynthetic process] evidence: TAS
            GeneID:9663 -> Biological process: GO:0044255 [cellular lipid metabolic process] evidence: TAS
            GeneID:9663 -> Biological process: GO:0044281 [small molecule metabolic process] evidence: TAS
            GeneID:9663 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: ISS
            GeneID:9663 -> Biological process: GO:0046474 [glycerophospholipid biosynthetic process] evidence: TAS
            GeneID:9663 -> Cellular component: GO:0005634 [nucleus] evidence: IEA
            GeneID:9663 -> Cellular component: GO:0005789 [endoplasmic reticulum membrane] evidence: TAS
            GeneID:9663 -> Cellular component: GO:0005829 [cytosol] evidence: IEA
ANNOTATIONS from NCBI Entrez Gene (20130726):
            NP_055461 -> EC 3.1.3.4

by @meso_cacase at DBCLS
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