LOCUS       NM_014621               1298 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens homeobox D4 (HOXD4), mRNA.
ACCESSION   NM_014621
VERSION     NM_014621.2  GI:23397671
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1298)
  AUTHORS   Zhang,H., He,J.W., Gao,G., Yue,H., Yu,J.B., Hu,W.W., Gu,J.M.,
            Hu,Y.Q., Li,M., Fu,W.Z., Liu,Y.J. and Zhang,Z.L.
  TITLE     Polymorphisms in the HOXD4 gene are not associated with peak bone
            mineral density in Chinese nuclear families
  JOURNAL   Acta Pharmacol. Sin. 31 (8), 977-983 (2010)
   PUBMED   20686522
  REMARK    GeneRIF: The results suggest that genetic polymorphisms in HOXD4
            may not be a major contributor to the observed variability in peak
            BMD in the lumbar spine and the hip in Chinese men and women
            GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   2  (bases 1 to 1298)
  AUTHORS   Ester,A.R., Weymouth,K.S., Burt,A., Wise,C.A., Scott,A.,
            Gurnett,C.A., Dobbs,M.B., Blanton,S.H. and Hecht,J.T.
  TITLE     Altered transmission of HOX and apoptotic SNPs identify a potential
            common pathway for clubfoot
  JOURNAL   Am. J. Med. Genet. A 149A (12), 2745-2752 (2009)
   PUBMED   19938081
  REMARK    GeneRIF: Observational study of gene-disease association and
            gene-gene interaction. (HuGE Navigator)
REFERENCE   3  (bases 1 to 1298)
  AUTHORS   Yerges,L.M., Klei,L., Cauley,J.A., Roeder,K., Kammerer,C.M.,
            Moffett,S.P., Ensrud,K.E., Nestlerode,C.S., Marshall,L.M.,
            Hoffman,A.R., Lewis,C., Lang,T.F., Barrett-Connor,E., Ferrell,R.E.,
            Orwoll,E.S. and Zmuda,J.M.
  CONSRTM   MrOS Research Group
  TITLE     High-density association study of 383 candidate genes for
            volumetric BMD at the femoral neck and lumbar spine among older men
  JOURNAL   J. Bone Miner. Res. 24 (12), 2039-2049 (2009)
   PUBMED   19453261
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   4  (bases 1 to 1298)
  AUTHORS   Tan,Y., Zhang,B., Wu,T., Skogerbo,G., Zhu,X., Guo,X., He,S. and
            Chen,R.
  TITLE     Transcriptional inhibiton of Hoxd4 expression by miRNA-10a in human
            breast cancer cells
  JOURNAL   BMC Mol. Biol. 10, 12 (2009)
   PUBMED   19232136
  REMARK    GeneRIF: microRNA-10a (miR-10a) targets a homologous DNA region in
            the promoter region of the hoxd4 gene and represses its expression
            at the transcriptional level
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1298)
  AUTHORS   van Scherpenzeel Thim,V., Remacle,S., Picard,J., Cornu,G.,
            Gofflot,F., Rezsohazy,R. and Verellen-Dumoulin,C.
  TITLE     Mutation analysis of the HOX paralogous 4-13 genes in children with
            acute lymphoid malignancies: identification of a novel germline
            mutation of HOXD4 leading to a partial loss-of-function
  JOURNAL   Hum. Mutat. 25 (4), 384-395 (2005)
   PUBMED   15776434
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   6  (bases 1 to 1298)
  AUTHORS   Scott,M.P.
  TITLE     Vertebrate homeobox gene nomenclature
  JOURNAL   Cell 71 (4), 551-553 (1992)
   PUBMED   1358459
REFERENCE   7  (bases 1 to 1298)
  AUTHORS   Cianetti,L., Di Cristofaro,A., Zappavigna,V., Bottero,L.,
            Boccoli,G., Testa,U., Russo,G., Boncinelli,E. and Peschle,C.
  TITLE     Molecular mechanisms underlying the expression of the human HOX-5.1
            gene
  JOURNAL   Nucleic Acids Res. 18 (15), 4361-4368 (1990)
   PUBMED   1975093
REFERENCE   8  (bases 1 to 1298)
  AUTHORS   McAlpine,P.J. and Shows,T.B.
  TITLE     Nomenclature for human homeobox genes
  JOURNAL   Genomics 7 (3), 460 (1990)
   PUBMED   1973146
REFERENCE   9  (bases 1 to 1298)
  AUTHORS   Boncinelli,E., Acampora,D., Pannese,M., D'Esposito,M., Somma,R.,
            Gaudino,G., Stornaiuolo,A., Cafiero,M., Faiella,A. and Simeone,A.
  TITLE     Organization of human class I homeobox genes
  JOURNAL   Genome 31 (2), 745-756 (1989)
   PUBMED   2576652
REFERENCE   10 (bases 1 to 1298)
  AUTHORS   Mavilio,F., Simeone,A., Giampaolo,A., Faiella,A., Zappavigna,V.,
            Acampora,D., Poiana,G., Russo,G., Peschle,C. and Boncinelli,E.
  TITLE     Differential and stage-related expression in embryonic tissues of a
            new human homoeobox gene
  JOURNAL   Nature 324 (6098), 664-668 (1986)
   PUBMED   2879245
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from X04706.1.
            This sequence is a reference standard in the RefSeqGene project.
            On Oct 1, 2002 this sequence version replaced gi:11024701.
            
            Summary: This gene belongs to the homeobox family of genes. The
            homeobox genes encode a highly conserved family of transcription
            factors that play an important role in morphogenesis in all
            multicellular organisms. Mammals possess four similar homeobox gene
            clusters, HOXA, HOXB, HOXC and HOXD, located on different
            chromosomes, consisting of 9 to 11 genes arranged in tandem. This
            gene is one of several homeobox HOXD genes located at 2q31-2q37
            chromosome regions. Deletions that removed the entire HOXD gene
            cluster or 5' end of this cluster have been associated with severe
            limb and genital abnormalities. The protein encoded by this gene
            may play a role in determining positional values in developing limb
            buds. Alternatively spliced variants have been described but their
            full length nature has not been determined. [provided by RefSeq,
            Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X04706.1, AK313885.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025083 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..1298
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q31.1"
     gene            1..1298
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /note="homeobox D4"
                     /db_xref="GeneID:3233"
                     /db_xref="HGNC:5138"
                     /db_xref="HPRD:00864"
                     /db_xref="MIM:142981"
     exon            1..682
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /inference="alignment:Splign:1.39.8"
     variation       103
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144430144"
     misc_feature    169..171
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /note="upstream in-frame stop codon"
     STS             181..1104
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /standard_name="UniSTS:480790"
                     /db_xref="UniSTS:480790"
     variation       182
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:16863572"
     STS             203..1043
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /db_xref="UniSTS:482013"
     variation       238
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372977271"
     variation       239
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:181916447"
     CDS             250..1017
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /note="Hox-4.2, mouse, homolog of homeo box X; homeobox
                     protein Hox-4B; homeobox protein HHO.C13; homeobox protein
                     Hox-5.1"
                     /codon_start=1
                     /product="homeobox protein Hox-D4"
                     /protein_id="NP_055436.2"
                     /db_xref="GI:23397672"
                     /db_xref="CCDS:CCDS2269.1"
                     /db_xref="GeneID:3233"
                     /db_xref="HGNC:5138"
                     /db_xref="HPRD:00864"
                     /db_xref="MIM:142981"
                     /translation="

MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGGGAQGADFQPPGLYPRPDFGEQPFGGSGPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPAPLPGARAYSQSDPKQPPSGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSSSCSSSVAPSQHLQPMAKDHHTDLTTL

"
     misc_feature    646..663
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (P09016.3);
                     Region: Antp-type hexapeptide"
     misc_feature    712..888
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /note="Homeodomain;  DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:28970"
     misc_feature    order(712..726,730..732,781..783,799..801,838..840,
                     844..849,856..861,865..873,877..882)
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:28970"
     misc_feature    order(718..720,727..729,847..849,856..861,868..870)
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:28970"
     variation       263
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:141531995"
     variation       306
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376860683"
     variation       313
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150414482"
     variation       340
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:187203814"
     variation       347
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149156170"
     variation       362
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200815560"
     variation       366
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374205432"
     variation       379
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138948127"
     variation       384
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:78015126"
     variation       391
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377617802"
     variation       409
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370038228"
     variation       414
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373841832"
     variation       491
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:104893636"
     variation       523
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:376322574"
     variation       560
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:370375150"
     variation       597
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:373583360"
     variation       616
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34727427"
     variation       652
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:149263765"
     variation       673
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375984352"
     exon            683..1298
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /inference="alignment:Splign:1.39.8"
     variation       687
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201185478"
     variation       692
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369822828"
     variation       693
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200241025"
     variation       740
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372805006"
     variation       762
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199697693"
     variation       779
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:139645088"
     variation       780
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147639954"
     variation       830
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201536867"
     variation       858
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142229749"
     variation       867
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:115586056"
     variation       891
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369450962"
     variation       912
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372512362"
     variation       927
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202044839"
     variation       945
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377042003"
     variation       963
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371037366"
     variation       981
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373439656"
     variation       998
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374609255"
     variation       1002
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367930048"
     STS             1012..1235
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /standard_name="STS-X17360"
                     /db_xref="UniSTS:77133"
     variation       1047
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369247267"
     variation       1050
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371995881"
     variation       1056
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:377123607"
     variation       1081
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:143890106"
     variation       1195
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1063656"
     variation       1218
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1063657"
     polyA_signal    1283..1288
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
     polyA_site      1298
                     /gene="HOXD4"
                     /gene_synonym="HHO.C13; Hox-4.2; HOX-5.1; HOX4; HOX4B"
                     /experiment="experimental evidence, no additional details
                     recorded"
ORIGIN      

cattaatatctggcaggggctctcaaatgtgccatagcaagctacttgattacacgtatgttatttagttaaatttgtgaaaattatgagatgctcaccaacccggtgataaacttgctccctcgccattggctggcctggtcacatggctgcccaactttattcagttgacagcaagtaggagggccctatggaaggagaaaaaaagacaacacgagaaaaattagtattttctaccttctgaaattaatggtcatgagttcgtatatggtgaactccaagtatgtggaccccaagttccctccgtgcgaggagtatttgcagggcggctacctaggcgagcagggcgccgactactacggcggcggcgcgcagggcgcagacttccagcccccggggctctacccacggcccgacttcggtgagcagcctttcggaggcagcggccccgggcctggctcggcgctgcctgcgcggggtcacggacaagagccaggcggccccggcggtcactacgccgctccaggagagccttgcccagctcccccggcgcctccgccggcgcccctgcctggcgcccgggcctacagtcagtccgaccccaagcagccgccctccgggacggcactcaagcagccggccgtggtctacccctggatgaagaaggtgcacgtgaattcggtgaaccccaactacaccggtggggaacccaagcggtcccgaacggcctacacccggcagcaagtcctagaactggaaaaagaatttcattttaacaggtatctgacaaggcgccgtcggattgaaatcgctcacaccctgtgtctgtcggagcgccagatcaagatctggttccagaaccggaggatgaagtggaaaaaagatcataagctgcccaacactaaaggcaggtcatcgtcctcatcttcctcctcatcttgctcctcctcagtcgcccccagccagcatttacagccgatggccaaagaccaccacacggacctgacgaccttatagaagtggggaccctgggcccatctctccctgcgcaccaggctgagccgaagctgcgggggcaggccgggcctgctgtcacctcgctgggctctaaggtactgtggggtggacctgggacaagcaggccgccctcggactaggttagcatcctgcccgagggcagccccctccctagagcgggatggggatgggagggggggcgggattctctctctaagtatattatatggcaggagctactgagaacataaaatcttggcgagtcattaaacttatgaaaa

//

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:3233 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: NAS
            GeneID:3233 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IEA
            GeneID:3233 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
            GeneID:3233 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: NAS
            GeneID:3233 -> Biological process: GO:0007275 [multicellular organismal development] evidence: NAS
            GeneID:3233 -> Cellular component: GO:0005634 [nucleus] evidence: NAS