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2019-03-25 14:29:30, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_014598               7978 bp    mRNA    linear   PRI 14-JUL-2013
DEFINITION  Homo sapiens suppressor of cytokine signaling 7 (SOCS7), mRNA.
ACCESSION   NM_014598 XM_371052
VERSION     NM_014598.2  GI:313850979
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7978)
  AUTHORS   Pharoah PD, Tsai YY, Ramus SJ, Phelan CM, Goode EL, Lawrenson K,
            Buckley M, Fridley BL, Tyrer JP, Shen H, Weber R, Karevan R, Larson
            MC, Song H, Tessier DC, Bacot F, Vincent D, Cunningham JM, Dennis
            J, Dicks E, Aben KK, Anton-Culver H, Antonenkova N, Armasu SM,
            Baglietto L, Bandera EV, Beckmann MW, Birrer MJ, Bloom G, Bogdanova
            N, Brenton JD, Brinton LA, Brooks-Wilson A, Brown R, Butzow R,
            Campbell I, Carney ME, Carvalho RS, Chang-Claude J, Chen YA, Chen
            Z, Chow WH, Cicek MS, Coetzee G, Cook LS, Cramer DW, Cybulski C,
            Dansonka-Mieszkowska A, Despierre E, Doherty JA, Dork T, du Bois A,
            Durst M, Eccles D, Edwards R, Ekici AB, Fasching PA, Fenstermacher
            D, Flanagan J, Gao YT, Garcia-Closas M, Gentry-Maharaj A, Giles G,
            Gjyshi A, Gore M, Gronwald J, Guo Q, Halle MK, Harter P, Hein A,
            Heitz F, Hillemanns P, Hoatlin M, Hogdall E, Hogdall CK, Hosono S,
            Jakubowska A, Jensen A, Kalli KR, Karlan BY, Kelemen LE, Kiemeney
            LA, Kjaer SK, Konecny GE, Krakstad C, Kupryjanczyk J, Lambrechts D,
            Lambrechts S, Le ND, Lee N, Lee J, Leminen A, Lim BK, Lissowska J,
            Lubinski J, Lundvall L, Lurie G, Massuger LF, Matsuo K, McGuire V,
            McLaughlin JR, Menon U, Modugno F, Moysich KB, Nakanishi T, Narod
            SA, Ness RB, Nevanlinna H, Nickels S, Noushmehr H, Odunsi K, Olson
            S, Orlow I, Paul J, Pejovic T, Pelttari LM, Permuth-Wey J, Pike MC,
            Poole EM, Qu X, Risch HA, Rodriguez-Rodriguez L, Rossing MA,
            Rudolph A, Runnebaum I, Rzepecka IK, Salvesen HB, Schwaab I, Severi
            G, Shen H, Shridhar V, Shu XO, Sieh W, Southey MC, Spellman P,
            Tajima K, Teo SH, Terry KL, Thompson PJ, Timorek A, Tworoger SS,
            van Altena AM, van den Berg D, Vergote I, Vierkant RA, Vitonis AF,
            Wang-Gohrke S, Wentzensen N, Whittemore AS, Wik E, Winterhoff B,
            Woo YL, Wu AH, Yang HP, Zheng W, Ziogas A, Zulkifli F, Goodman MT,
            Hall P, Easton DF, Pearce CL, Berchuck A, Chenevix-Trench G,
            Iversen E, Monteiro AN, Gayther SA, Schildkraut JM and Sellers TA.
  CONSRTM   Australian Cancer Study; Australian Ovarian Cancer Study Group
  TITLE     GWAS meta-analysis and replication identifies three new
            susceptibility loci for ovarian cancer
  JOURNAL   Nat. Genet. 45 (4), 362-370 (2013)
   PUBMED   23535730
REFERENCE   2  (bases 1 to 7978)
  AUTHORS   Noguchi,S., Yamada,N., Kumazaki,M., Yasui,Y., Iwasaki,J., Naito,S.
            and Akao,Y.
  TITLE     socs7, a target gene of microRNA-145, regulates interferon-beta
            induction through STAT3 nuclear translocation in bladder cancer
            cells
  JOURNAL   Cell Death Dis 4, E482 (2013)
   PUBMED   23392170
  REMARK    GeneRIF: SOCS7 functioned as an oncogene, the finding that revealed
            a novel mechanism of carcinogenesis in bladder cancer cells.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7978)
  AUTHORS   Ge,D., Gao,A.C., Zhang,Q., Liu,S., Xue,Y. and You,Z.
  TITLE     LNCaP prostate cancer cells with autocrine interleukin-6 expression
            are resistant to IL-6-induced neuroendocrine differentiation due to
            increased expression of suppressors of cytokine signaling
  JOURNAL   Prostate 72 (12), 1306-1316 (2012)
   PUBMED   22213096
  REMARK    GeneRIF: LNCaP-S17 cells are resistant to exogenous IL-6-induced
            neuroendocrine differentiation due to increased levels of CIS/SOCS7
            that block activation of JAK2-STAT3 pathways.
REFERENCE   4  (bases 1 to 7978)
  AUTHORS   Pazienza,V., Vinciguerra,M., Andriulli,A. and Mangia,A.
  TITLE     Hepatitis C virus core protein genotype 3a increases SOCS-7
            expression through PPAR-{gamma} in Huh-7 cells
  JOURNAL   J. Gen. Virol. 91 (PT 7), 1678-1686 (2010)
   PUBMED   20357037
  REMARK    GeneRIF: findings show that PPAR-gamma is involved in the
            regulation of SOCS-7 expression by hepatitis C virus core protein
            genotype 3a
REFERENCE   5  (bases 1 to 7978)
  AUTHORS   Sasi,W., Jiang,W.G., Sharma,A. and Mokbel,K.
  TITLE     Higher expression levels of SOCS 1,3,4,7 are associated with
            earlier tumour stage and better clinical outcome in human breast
            cancer
  JOURNAL   BMC Cancer 10, 178 (2010)
   PUBMED   20433750
  REMARK    GeneRIF: Higher mRNA expression levels of SOCS1, 3, 4 and 7 are
            significantly associated with earlier tumour stage and better
            clinical outcome in human breast cancer.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7978)
  AUTHORS   Krebs,D.L., Uren,R.T., Metcalf,D., Rakar,S., Zhang,J.G., Starr,R.,
            De Souza,D.P., Hanzinikolas,K., Eyles,J., Connolly,L.M.,
            Simpson,R.J., Nicola,N.A., Nicholson,S.E., Baca,M., Hilton,D.J. and
            Alexander,W.S.
  TITLE     SOCS-6 binds to insulin receptor substrate 4, and mice lacking the
            SOCS-6 gene exhibit mild growth retardation
  JOURNAL   Mol. Cell. Biol. 22 (13), 4567-4578 (2002)
   PUBMED   12052866
REFERENCE   7  (bases 1 to 7978)
  AUTHORS   Cooney,R.N.
  TITLE     Suppressors of cytokine signaling (SOCS): inhibitors of the
            JAK/STAT pathway
  JOURNAL   Shock 17 (2), 83-90 (2002)
   PUBMED   11837794
  REMARK    Review article
REFERENCE   8  (bases 1 to 7978)
  AUTHORS   Dogusan,Z., Hooghe-Peters,E.L., Berus,D., Velkeniers,B. and
            Hooghe,R.
  TITLE     Expression of SOCS genes in normal and leukemic human leukocytes
            stimulated by prolactin, growth hormone and cytokines
  JOURNAL   J. Neuroimmunol. 109 (1), 34-39 (2000)
   PUBMED   10969179
REFERENCE   9  (bases 1 to 7978)
  AUTHORS   Hilton,D.J., Richardson,R.T., Alexander,W.S., Viney,E.M.,
            Willson,T.A., Sprigg,N.S., Starr,R., Nicholson,S.E., Metcalf,D. and
            Nicola,N.A.
  TITLE     Twenty proteins containing a C-terminal SOCS box form five
            structural classes
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 95 (1), 114-119 (1998)
   PUBMED   9419338
REFERENCE   10 (bases 1 to 7978)
  AUTHORS   Matuoka,K., Miki,H., Takahashi,K. and Takenawa,T.
  TITLE     A novel ligand for an SH3 domain of the adaptor protein Nck bears
            an SH2 domain and nuclear signaling motifs
  JOURNAL   Biochem. Biophys. Res. Commun. 239 (2), 488-492 (1997)
   PUBMED   9344857
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC183084.2, BC128607.1, AB005216.1 and AC124789.12.
            On Dec 10, 2010 this sequence version replaced gi:53831996.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB005216.1, BC128607.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025084, ERS025085 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-559               AC183084.2         1701-2259           c
            560-1189            BC128607.1         16-645
            1190-1190           AB005216.1         701-701
            1191-2018           BC128607.1         647-1474
            2019-7978           AC124789.12        3601-9560           c
FEATURES             Location/Qualifiers
     source          1..7978
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q12"
     gene            1..7978
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /note="suppressor of cytokine signaling 7"
                     /db_xref="GeneID:30837"
                     /db_xref="HGNC:29846"
                     /db_xref="HPRD:12299"
                     /db_xref="MIM:608788"
     exon            1..909
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /inference="alignment:Splign:1.39.8"
     CDS             122..1867
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /note="NCK-associated protein 4; Nck, Ash and
                     phospholipase C binding protein; NAP-4; SOCS-7; nck, Ash
                     and phospholipase C gamma-binding protein"
                     /codon_start=1
                     /product="suppressor of cytokine signaling 7"
                     /protein_id="NP_055413.1"
                     /db_xref="GI:53831997"
                     /db_xref="CCDS:CCDS32637.1"
                     /db_xref="GeneID:30837"
                     /db_xref="HGNC:29846"
                     /db_xref="HPRD:12299"
                     /db_xref="MIM:608788"
                     /translation="
MVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVEPST
"
     misc_feature    491..1603
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (O14512.2);
                     Region: Mediates interaction with SORBS3"
     misc_feature    1286..1588
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /note="Src homology 2 (SH2) domain found in  suppressor of
                     cytokine signaling (SOCS) proteins; Region: SH2_SOCS7;
                     cd10388"
                     /db_xref="CDD:198251"
     misc_feature    order(1340..1342,1394..1396,1400..1402,1424..1426,
                     1463..1465)
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /note="phosphotyrosine binding pocket [polypeptide
                     binding]; other site"
                     /db_xref="CDD:198251"
     misc_feature    order(1493..1495,1499..1501,1553..1555)
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /note="hydrophobic binding pocket [polypeptide binding];
                     other site"
                     /db_xref="CDD:198251"
     misc_feature    1658..1804
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /note="SOCS (suppressors of cytokine signaling) box of
                     SOCS7-like proteins. Together with CIS1, the CIS/SOCS
                     family of proteins is characterized by the presence of a
                     C-terminal SOCS box and a central SH2 domain. SOCS7 is
                     important in the functioning of neuronal...; Region:
                     SOCS_SOCS7; cd03741"
                     /db_xref="CDD:58145"
     misc_feature    order(1661..1678,1694..1696,1715..1717,1733..1735,
                     1748..1750)
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /note="putative elongin B/C interaction [polypeptide
                     binding]; other site"
                     /db_xref="CDD:58145"
     variation       255
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:182736053"
     variation       257
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113299524"
     variation       379
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:41377745"
     variation       414
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201577908"
     variation       499
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:41351844"
     variation       542
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372829995"
     variation       608
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:201639550"
     variation       644
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:56279143"
     variation       657..658
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace=""
                     /replace="gca"
                     /db_xref="dbSNP:55849419"
     variation       681..682
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace=""
                     /replace="gca"
                     /db_xref="dbSNP:60453610"
     variation       682
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace=""
                     /replace="gca"
                     /db_xref="dbSNP:41492748"
     variation       730
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:376084903"
     variation       783
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200638330"
     variation       794
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368529614"
     variation       802
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370980742"
     variation       904
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375541134"
     exon            910..974
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /inference="alignment:Splign:1.39.8"
     variation       929
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:75445121"
     variation       930
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:76549267"
     variation       947
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:139493404"
     variation       949
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368047299"
     exon            975..1079
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /inference="alignment:Splign:1.39.8"
     variation       990
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368507568"
     variation       1008
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:77546775"
     variation       1037
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:199883782"
     variation       1057
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146657304"
     variation       1067
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:140733557"
     exon            1080..1181
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /inference="alignment:Splign:1.39.8"
     variation       1084
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144493134"
     variation       1147
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142786789"
     variation       1158
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145376452"
     variation       1159
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149190855"
     variation       1162
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:371505316"
     exon            1182..1312
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /inference="alignment:Splign:1.39.8"
     variation       1193
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199820589"
     variation       1194
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201354583"
     variation       1221
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369677064"
     variation       1239
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373112910"
     variation       1249
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200305110"
     variation       1266
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370033423"
     variation       1269
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372664557"
     exon            1313..1481
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /inference="alignment:Splign:1.39.8"
     variation       1382
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:143317326"
     variation       1478
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148327709"
     exon            1482..1610
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /inference="alignment:Splign:1.39.8"
     variation       1522
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140480789"
     variation       1555
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147043285"
     exon            1611..1746
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /inference="alignment:Splign:1.39.8"
     variation       1633
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138279795"
     variation       1636
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61744884"
     variation       1675
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201020366"
     exon            1747..1897
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /inference="alignment:Splign:1.39.8"
     variation       1762
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147429718"
     variation       1813
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200707695"
     variation       1822
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138060923"
     variation       1824
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:369848227"
     variation       1836
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:55687042"
     exon            1898..7978
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /inference="alignment:Splign:1.39.8"
     variation       1954..1955
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace=""
                     /replace="ag"
                     /db_xref="dbSNP:370878759"
     variation       1957..1958
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace=""
                     /replace="ag"
                     /db_xref="dbSNP:56126906"
     variation       2015
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3748728"
     variation       2046
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:145907745"
     variation       2047
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:138717560"
     variation       2052
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3193291"
     variation       2195
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3748727"
     variation       2250
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace=""
                     /replace="caggt"
                     /db_xref="dbSNP:41502245"
     variation       2255
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:56259056"
     variation       2385
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:7221139"
     variation       2562
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:185290596"
     variation       2607
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191417154"
     variation       2632
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:41421647"
     variation       2717
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:183194230"
     variation       2994
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148066376"
     variation       3064
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141768666"
     variation       3072
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:146025537"
     variation       3120
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:41465244"
     variation       3142
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:370479771"
     variation       3168
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:41350045"
     variation       3192
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:41470153"
     variation       3221
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3748726"
     variation       3269..3270
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:35011456"
     variation       3300..3301
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:34408289"
     variation       3321
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:41476051"
     variation       3505
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143371485"
     variation       3600
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191704465"
     variation       3670
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1045638"
     variation       3739
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183283986"
     variation       3740
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369866206"
     variation       3837..3838
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:111228668"
     variation       3840..3841
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:377182110"
     variation       3848..3849
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:372764632"
     variation       3946
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146103054"
     variation       4079
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374527613"
     variation       4085
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:187955988"
     variation       4116
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:78913515"
     variation       4170
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:191262759"
     variation       4221
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377293884"
     variation       4234
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368417658"
     variation       4269
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3748725"
     variation       4308
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:72834024"
     variation       4321
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:73298678"
     variation       4383
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3748724"
     variation       4414
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183782815"
     variation       4501
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:187767364"
     variation       4546
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376495923"
     variation       4586
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371819588"
     variation       4591
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139731078"
     variation       4724
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375072810"
     variation       4741
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3748723"
     variation       4784
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149772292"
     variation       4833
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:116439453"
     variation       4844
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:115900316"
     variation       4847
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145693495"
     STS             4859..5036
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /standard_name="D10S2448"
                     /db_xref="UniSTS:474444"
     variation       4906
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:192891373"
     STS             4936..5037
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /standard_name="D8S2282"
                     /db_xref="UniSTS:473910"
     STS             4963..5041
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /standard_name="RH36905"
                     /db_xref="UniSTS:87932"
     variation       5175
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148925419"
     variation       5218
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:117177630"
     variation       5219
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184902717"
     variation       5239
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145694149"
     variation       5332
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369632145"
     variation       5379
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147745237"
     variation       5383
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374068854"
     variation       5420
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142580652"
     variation       5422
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:190143631"
     variation       5434
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:181796130"
     variation       5503
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:116178054"
     variation       5557
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113484307"
     variation       5632
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:118104419"
     variation       5673
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138728763"
     variation       5742
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140166851"
     variation       5757
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:184560147"
     variation       5767
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150300962"
     variation       5785
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:137941819"
     variation       5806
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367744908"
     variation       5987
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114743406"
     variation       5996..5997
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace=""
                     /replace="tg"
                     /db_xref="dbSNP:143774148"
     variation       6014..6015
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace=""
                     /replace="gt"
                     /db_xref="dbSNP:58800510"
     variation       6020
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146044214"
     STS             6206..6317
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /standard_name="A005S24"
                     /db_xref="UniSTS:29024"
     STS             6206..6317
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /standard_name="G20462"
                     /db_xref="UniSTS:29023"
     variation       6219
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138752854"
     variation       6269
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141753196"
     variation       6281
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:372136066"
     variation       6408
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146228532"
     variation       6450
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:16968693"
     variation       6451
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:60045196"
     variation       6468
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148748932"
     variation       6685
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141487587"
     variation       6697
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:114719036"
     variation       6728
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150845815"
     variation       6799
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:368418407"
     variation       6815
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:189344139"
     variation       6923
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:139279824"
     variation       6980
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:112667628"
     variation       7011
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:145346717"
     variation       7131
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:73298684"
     variation       7161
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374642319"
     variation       7174
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:182035720"
     variation       7222
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147747951"
     variation       7244
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111278870"
     variation       7255
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199532320"
     variation       7260
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367839698"
     variation       7282
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:371506757"
     variation       7361
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:12943094"
     variation       7419..7420
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:111645811"
     variation       7425
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:190919838"
     variation       7426..7427
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:376534978"
     variation       7442
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181219128"
     variation       7503
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186461091"
     variation       7516
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:74892863"
     variation       7529
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:12941155"
     variation       7581
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61377194"
     variation       7601
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:140974966"
     variation       7855
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:79240905"
     variation       7939
                     /gene="SOCS7"
                     /gene_synonym="NAP4; NCKAP4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376610237"
ORIGIN      
ccttggctatggagaggcggcccccgagccaggccctccgccaccgcccccgggccatggccccccgccgccacccttcctcgcgcggcccggcccgcggggctcccggccgccgcagctgatggtgttccgcaacgtgggtcggccgccggaggaggaggacgtggaggcggccccggagccgggaccctcggaactgctgtgtccccggcaccgctgtgccctggaccccaaggccctgccgccgggcttggcgctcgagcggacctggggcccggcggctggactagaggcgcagttggcggctctggggctcgggcagccggcggggccgggggtcaagacagtcggtgggggttgctgcccgtgtccgtgtcctcctcagccgccccctccgcagccccagccgcctgctgccgccccgcaggccggggaggaccccacggaaacgagcgacgcgctgctggtcctggagggcttggaatcggaggccgagagcctggagactaacagctgctcggaagaggagctcagcagcccgggtcgcggaggaggagggggcggccggcttctgctgcagcccccaggccctgaattacctccggtgcccttcccgctgcaggacttggtccctctggggcgcctgagtagaggggagcagcagcagcagcagcagcagcaacctcccccgcccccgcctcctcccgggcccctccggccactcgcgggtccttctcggaagggctccttcaaaatccgcctcagtcgcctctttcgcaccaagagctgcaacggtggctccggcggtggggatgggaccggcaagaggccttctggagagctggctgcttcagctgcgagcctgacagacatgggaggctctgcgggccgggagctggacgcggggaggaaacccaagttgacaagaactcaaagtgccttttctccggtctccttcagccccctgttcacaggtgaaactgtgtcgcttgtggatgtggacatttctcagcggggcctgacctctccacaccctccaactccccctcctcctccgagaagaagcctcagcctcctagatgatatcagtgggacgctgcctacatctgtccttgtggctccgatggggtcttccttgcagtctttccccctacctccgcctcctccaccccatgccccagatgcatttccccggattgctcccatccgagcagctgaatccctgcacagccaacccccacagcacctccagtgtcccctctaccggcctgactcgagcagctttgcagccagccttcgagagttggagaagtgtggttggtattgggggccaatgaattgggaagatgcagagatgaagctgaaagggaaaccagatggttctttcctggtacgagacagttctgatcctcgttacatcctgagcctcagtttccgatcacagggtatcacccaccacactagaatggagcactacagaggaaccttcagcctgtggtgtcatcccaagtttgaggaccgctgtcaatctgttgtagagtttattaagagagccattatgcactccaagaatggaaagtttctctatttcttaagatccagggttccaggactgccaccaactcctgtccagctgctctatccagtgtcccgattcagcaatgtcaaatccctccagcacctttgcagattccggatacgacagctcgtcaggatagatcacatcccagatctcccactgcctaaacctctgatctcttatatccgaaagttctactactatgatcctcaggaagaggtatacctgtctctaaaggaagcgcagctcatttccaaacagaagcaagaggtggaaccctccacgtagcgaggggctccctgctggtcaccaccaagggcatttggttgccaagctccagctttgaagaaccaaattaagctaccatgaaaagaagaggaaaagtgagggaacaggaaggttgggattctctgtgcagagactttggttccccacgcagccctggggcttggaagaagcacatgaccgtactctgcgtggggctccacctcacacccacccctgggcatcttaggactggaggggctccttggaaaactggaagaagtctcaacactgtttctttttcagaagttttgtttttgatatttatattacttggtatggaaaactcaccttgaaggcagttggggtttgtgcccgttggattgaaagtggtgcgaagggtgagcaggtccaaagaaggggtgggaggagggaacaggggacggccattcagctggtgccaaaggcagagttagagtctgtgctgtgggcctggaagatgggaggaggggcttgaggtttgcaaaggactgggagttcctgaggaagggggaatctgcctcttgttgccatgggcagctgttgtaggagcaggagagaaaggagggtgggtggtctcgaaaagaatattgggcaaaacctagccaattggccttagctgggagaagtagtgactcctgcatccttttttaaggtttaggaacctgagttcagaaacacctctcatggaagctgtactagttgtgatttacttaattccttaagttccatgacctgaagttaaccccgttcttcctctgctctcaacccattgccccttgagataactgtacatgtcactctgatcatggtaacagcatccctattgcttctgccagctgtcatggcaatcgtgtttcccatcacctgggcggttcagagccagtcatgggctgctgaatttaatggagcatgtttccaggttcttcatggcaaactgtactcatgacttaggagtgagtgttacttccatgtgcctgtcagcttgtgagggggaatgtggaggaaggtgagaaatacagctcccacagttgtgctcttcctagaggaagctctcagaacgcagccctcacgggatttccttaggtcagaggagagcatcgcatctcacgtttttaggtttatcactgccatcccacttctgggatgggaggtagcaagggcttctgtattttcttgtgttcattctagcaacccagacatttccggatcagatcctgctggtctccactcactggaaagtctgccagatgccgatttgagagctgcctgtccctgctttcaggaggagcggggagaaaaactccaatggtctttaatggtttctgcagctggccatggccaattcatatgacattgtgagtttgctttcttatagagctgctctggggagaggtttgctattgagatgtaacagtggagctgttgggtcttcatgactcctttgcgtgtgttccatgggactctctttctgggttccccatgcttatagttgcctcgtgtcacaagacagatactaatgtcaggtttgtggcttcctgatggtttgggtggggccccagtgtcctggtaatttataggactgcctcatctgggagcattgccttcttccttagtcccacgtggagtgaccagtcttcctccttgtagctgaacagggaggaaacttgcaccattacctgactgtggaagggtggcccacaagatgagctgtgcaccataaacacagcccacctctgatttgtcatgtggtacctcttctttccttggcttccatggtagtattaccaactaagcaagattgtgatcccagaaattggcttagcatgtgagtgttgcctcgtgagagtacaagtaatataactcgccatcttgcaggaagtgccaccccaatatagagcctgaagttggaatctgttgagatccttgggtggctgatatacagcctgggatctttcttttttttgttccttttcaaccacccataattttaatattattttttagtgtgtgtgtgcctggctttgcgctagatattgtagaaaacaaaaaaggtaaaagacgtaatatgtggcctaagggagcttttaggtgactgctgcacatcaagcagaaaatcaaggactatctaaagacgtttatagtagataagatcagggtagaccagatggtctgggaaagttctgtgcctctgaggctttgggttgtagtcaatggcaggacagacagtgagatgaaaaacacatgagcaaaagcaaggaagcagaaatctgcatggcatgtactgaacagtgcacagccctgttagagcaacatggttaaagaatcctttccagtgcggttttctagatggaagcttcccagccaccaggcagacctgagtgccgaggggttatgatggtgaggtggagcccaaagcccaaaggagtcagcaaggctcctgcccattgccagggcctcactatggtcagctcaggccatgtgagggaggcagagcctccgcaccccctgtgttactggggtttcttctggagaactcatacattcaggtacaaaacaaaccaactgaggaggtgtgacccaacctcaccacccacctttctcctcctggggagtgtcgtgttgaactgtgtctgtgtcagtgcactggtcccagccctggccgcagcctagtcctttctctgtggagtgggctgcaaaacagcagcgcaagaggagacagtcttcgtcaggtgtgggtgtttggtgcctgcatgggtggccttgcacagagcagttaggggaagatgagggggaggcatggggctgggccagctctctgggatacagcctggtcagagagtaaatggagcagaggaacaggtgtggcagcacctgcccttcacctccctgaccaggcccgtccctccttcgccagtgctgtgcagagctcatttaaatgtattcctttctaggtctgggcgcggtggctcacgcctgtaatcccagcactttgggaggctgaggtgggtggatcatgaggtcgggagttcaagaccagcttggccaaacagtgaaaccctatctctactaaaatacaaaaattagctgggcatggtggcatgcgcctgtagtcccagctacttgggaggctgagacaggagaattgcttgaacccaggaggcggaggttgcactgagccgagattgcgccactgccctctagcctagacgacagagtgagactccatctcaaaaaaaataaataatttctttctggttgtattttcaagtcacaaattggaaaaggcttacatctagggacccactgttgattcctaagttgtgggtgggtgatatcagtggcctcagtgcctgcataaccctcacctgtttatgactgatctactgtaaccttcctcaggttgagagtgagctgctgtgagccagtgacaactactgctacaacttgctgttacttgaaattcgtgtgctatgttggtagcacaggagtaggcgggcgggggttttggtgtgggcactaggtaagtgggtggcaaccggctctttgggaccattggtgctgacctttgcctggtcacctgcctgtgcctaggccaagtgaatgttacatcttggaacctgagccatggaggtggcgccacctccctgaggagaaaggtgtggccaaaggaaactcctgcatggctcctgctccttccccttccctacatttcacttgggctaatgatgtaagccccccttgaggttggggatggtgtggagatagctgcagacacccctgtaacagacatccaggaagaattagggagtgggggtaattatagttcctaggtctaggggtgagaggtgggagtagaaccagaagtgccctggaatccagccgtgtcagccctcaccccagggcccccaggaaagcatggcctgcttgaagccctctgctccctgcagaaactggggcgaggaggagctttttccttcagttagatctttcccttccctgctgcctcgctcccttagctttggagccctaaagttagtggacaagacactgggataaagctctatggctgctggaaggaggtctgagtctgtgtgtgtgcatatgcatgcatgtgtgtgtgtgtgtgtgtcctcatttgcagaagtcttgctaccagttagggtgttaagagcatctccactgggcggagacctggcatttgttttccactgttaagagaatgacacaccccctgtcatgtaagggaggagctattgagttagacattttccctatgggaatcctcggtttggtttgtgggaaaggagggaatggataagtgatttttatctctaatcgtcaacacagctgttcttccactgaatttgtgctattgcatacatgtagccatctttcttttcactgcagcagtgtttatcagtagttcaaaatgatttatttgctcctggggagtaaaaccttttttattaaaaaaagaaaaagaaaaaaaaaagaaagaaaagtgtgcccccctcctatgctgcgatagctataaaatgattgggtcacaaaggtcaagtctgcacgtccctgtggtagaccctgctttcacattggagccttcacactcagcacaaaatgattggaggccttgataaaatggagagcaaagtcttgggagcagtgaaatgggggttggatcatagagacaggcgctggggactcgggtactgcagttaggaaagtagcgttatgagttgtactgaaaatgttgattctctaatctgccagaaaaggacctgtcttttcatgcagatttcatattgtctttgtccttttcattgcttcttgaccttcctggcaggtgtcgctcagtttcttcctgtttcccttcctgtcctctccacacctgctatcccgtcccactcccatctacctcccgggaagccagccctgcatgctgagtttgtgacctgcttcattcccatttcatttctagagggtttagaggtgacctggaaccgttccctttccctctcctaccccctcctctgcaacaccaagaggcctggaggggcagacagaaagcagccagccacggcgggaagacatgcatgtttggttgcagctggactgcgatcgtagttcctcctggagatagagtgtgaggaacttaggacactcttcctcagactctgggatcatcacataccacactgccccgctcagagtttcgtcctgagctccctaaccagctcaggtggagcagaagcctgctctcactcctccatctctggtgctcccttgggcggggacctgtccctcactcttaggcccagaacctgtccaagggacaggtagggtccaggtgccactttgggtagctggctgttggaatgcccacactggtgctgcctgtggcatagccactgctgtacgtttttggttgtttttaagaaactcgatgaagaggggtgtcattctgggctcggggtggttgccaatttttcaccagaaagggagccaccccttgcaaccacttctgtctccgttagccccccctctgccctcctccaagccaaagcgtggcctggcttttgtcttcccatttagttttcctcttttacccttccttttgtgcttaatttattaaaatagttgctgtataatttattttcataaactataaaaaaatactaaatggttaaaatagacttgcaggccaatcttaaatggggtgggaggggtctgagggtgggatggggaaagggaaagaggttttgatataaacaaaacaaatgcactttgggtgtgttttggtatttttctggggatagagggggtggggttagggatgtccctgtagattagttccagaatggggtgtctgtatatactgtattaataggcatgtttgactctcgtaaagggacgttagtagctgctgcaggtcctgtttggaaaccccatgtacaattcccagttttttgtaagtgtcagtgcgagagacatttgactcttgtgtttgtatctcctttttatgattgctgtacctacccatgtctttttggggaggggtgaaaagagatttgaaataaaaatgtttagaaatta
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:30837 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:30837 -> Molecular function: GO:0017124 [SH3 domain binding] evidence: NAS
            GeneID:30837 -> Biological process: GO:0008150 [biological_process] evidence: ND
            GeneID:30837 -> Biological process: GO:0008286 [insulin receptor signaling pathway] evidence: IEA
            GeneID:30837 -> Biological process: GO:0009968 [negative regulation of signal transduction] evidence: IEA
            GeneID:30837 -> Biological process: GO:0016567 [protein ubiquitination] evidence: IEA
            GeneID:30837 -> Biological process: GO:0035556 [intracellular signal transduction] evidence: IEA
            GeneID:30837 -> Biological process: GO:0040008 [regulation of growth] evidence: IEA
            GeneID:30837 -> Biological process: GO:0045444 [fat cell differentiation] evidence: IEA
            GeneID:30837 -> Cellular component: GO:0005634 [nucleus] evidence: IEA
            GeneID:30837 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
            GeneID:30837 -> Cellular component: GO:0005886 [plasma membrane] evidence: IEA

by @meso_cacase at DBCLS
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