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2020-10-26 18:11:33, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_014246              11389 bp    mRNA    linear   PRI 11-MAY-2013
DEFINITION  Homo sapiens cadherin, EGF LAG seven-pass G-type receptor 1
            (CELSR1), mRNA.
ACCESSION   NM_014246
VERSION     NM_014246.1  GI:7656966
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 11389)
  AUTHORS   Allache,R., De Marco,P., Merello,E., Capra,V. and Kibar,Z.
  TITLE     Role of the planar cell polarity gene CELSR1 in neural tube defects
            and caudal agenesis
  JOURNAL   Birth Defects Res. Part A Clin. Mol. Teratol. 94 (3), 176-181
            (2012)
   PUBMED   22371354
  REMARK    GeneRIF: CELSR1 is a risk factor for neural tube defects or caudal
            agenesis via pathogenic role of planar cell polarity signaling in
            these malformations.
REFERENCE   2  (bases 1 to 11389)
  AUTHORS   Robinson,A., Escuin,S., Doudney,K., Vekemans,M., Stevenson,R.E.,
            Greene,N.D., Copp,A.J. and Stanier,P.
  TITLE     Mutations in the planar cell polarity genes CELSR1 and SCRIB are
            associated with the severe neural tube defect craniorachischisis
  JOURNAL   Hum. Mutat. 33 (2), 440-447 (2012)
   PUBMED   22095531
  REMARK    GeneRIF: Missense variants in CELSR1 may represent a cause of
            craniorachischisis in humans, as in mice, with defective planar
            cell polarity protein trafficking to the plasma membrane a likely
            pathogenic mechanism.
REFERENCE   3  (bases 1 to 11389)
  AUTHORS   Gouveia,L.O., Sobral,J., Vicente,A.M., Ferro,J.M. and Oliveira,S.A.
  TITLE     Replication of the CELSR1 association with ischemic stroke in a
            Portuguese case-control cohort
  JOURNAL   Atherosclerosis 217 (1), 260-262 (2011)
   PUBMED   21511255
  REMARK    GeneRIF: CELSR1 may have a role in ischemic stroke, as shown in a
            Portuguese case-control cohort
REFERENCE   4  (bases 1 to 11389)
  AUTHORS   Yates,L.L., Schnatwinkel,C., Murdoch,J.N., Bogani,D.,
            Formstone,C.J., Townsend,S., Greenfield,A., Niswander,L.A. and
            Dean,C.H.
  TITLE     The PCP genes Celsr1 and Vangl2 are required for normal lung
            branching morphogenesis
  JOURNAL   Hum. Mol. Genet. 19 (11), 2251-2267 (2010)
   PUBMED   20223754
  REMARK    GeneRIF: The planar cell polarity genes Celsr1 and Vangl2 are
            required for normal lung branching morphogenesis.
REFERENCE   5  (bases 1 to 11389)
  AUTHORS   Yoshida,T., Kato,K., Yokoi,K., Oguri,M., Watanabe,S., Metoki,N.,
            Yoshida,H., Satoh,K., Aoyagi,Y., Nozawa,Y. and Yamada,Y.
  TITLE     Association of genetic variants with hemorrhagic stroke in Japanese
            individuals
  JOURNAL   Int. J. Mol. Med. 25 (4), 649-656 (2010)
   PUBMED   20198315
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   6  (bases 1 to 11389)
  AUTHORS   Nollet,F., Kools,P. and van Roy,F.
  TITLE     Phylogenetic analysis of the cadherin superfamily allows
            identification of six major subfamilies besides several solitary
            members
  JOURNAL   J. Mol. Biol. 299 (3), 551-572 (2000)
   PUBMED   10835267
  REMARK    Review article
REFERENCE   7  (bases 1 to 11389)
  AUTHORS   Wu,Q. and Maniatis,T.
  TITLE     Large exons encoding multiple ectodomains are a characteristic
            feature of protocadherin genes
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 97 (7), 3124-3129 (2000)
   PUBMED   10716726
REFERENCE   8  (bases 1 to 11389)
  AUTHORS   Dunham,I., Shimizu,N., Roe,B.A., Chissoe,S., Hunt,A.R.,
            Collins,J.E., Bruskiewich,R., Beare,D.M., Clamp,M., Smink,L.J.,
            Ainscough,R., Almeida,J.P., Babbage,A., Bagguley,C., Bailey,J.,
            Barlow,K., Bates,K.N., Beasley,O., Bird,C.P., Blakey,S.,
            Bridgeman,A.M., Buck,D., Burgess,J., Burrill,W.D., O'Brien,K.P. et
            al.
  TITLE     The DNA sequence of human chromosome 22
  JOURNAL   Nature 402 (6761), 489-495 (1999)
   PUBMED   10591208
  REMARK    Erratum:[Nature 2000 Apr 20;404(6780):904]
REFERENCE   9  (bases 1 to 11389)
  AUTHORS   Wu,Q. and Maniatis,T.
  TITLE     A striking organization of a large family of human neural
            cadherin-like cell adhesion genes
  JOURNAL   Cell 97 (6), 779-790 (1999)
   PUBMED   10380929
REFERENCE   10 (bases 1 to 11389)
  AUTHORS   Hadjantonakis,A.K., Sheward,W.J., Harmar,A.J., de Galan,L.,
            Hoovers,J.M. and Little,P.F.
  TITLE     Celsr1, a neural-specific gene encoding an unusual seven-pass
            transmembrane receptor, maps to mouse chromosome 15 and human
            chromosome 22qter
  JOURNAL   Genomics 45 (1), 97-104 (1997)
   PUBMED   9339365
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AF231024.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: The protein encoded by this gene is a member of the
            flamingo subfamily, part of the cadherin superfamily. The flamingo
            subfamily consists of nonclassic-type cadherins; a subpopulation
            that does not interact with catenins. The flamingo cadherins are
            located at the plasma membrane and have nine cadherin domains,
            seven epidermal growth factor-like repeats and two laminin A G-type
            repeats in their ectodomain. They also have seven transmembrane
            domains, a characteristic unique to this subfamily. It is
            postulated that these proteins are receptors involved in
            contact-mediated communication, with cadherin domains acting as
            homophilic binding regions and the EGF-like domains involved in
            cell adhesion and receptor-ligand interactions. This particular
            member is a developmentally regulated, neural-specific gene which
            plays an unspecified role in early embryogenesis. [provided by
            RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF231024.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           ERS025081, ERS025082 [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..11389
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q13.3"
     gene            1..11389
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="cadherin, EGF LAG seven-pass G-type receptor 1"
                     /db_xref="GeneID:9620"
                     /db_xref="HGNC:1850"
                     /db_xref="HPRD:05160"
                     /db_xref="MIM:604523"
     CDS             1..9045
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="protocadherin flamingo 2; cadherin, EGF LAG
                     seven-pass G-type receptor 1 (flamingo homolog,
                     Drosophila); flamingo homolog 2; cadherin family member 9"
                     /codon_start=1
                     /product="cadherin EGF LAG seven-pass G-type receptor 1
                     precursor"
                     /protein_id="NP_055061.1"
                     /db_xref="GI:7656967"
                     /db_xref="CCDS:CCDS14076.1"
                     /db_xref="GeneID:9620"
                     /db_xref="HGNC:1850"
                     /db_xref="HPRD:05160"
                     /db_xref="MIM:604523"
                     /translation="
MAPPPPPVLPVLLLLAAAAALPAMGLRAAAWEPRVPGGTRAFALRPGCTYAVGAACTPRAPRELLDVGRDGRLAGRRRVSGAGRPLPLQVRLVARSAPTALSRRLRARTHLPGCGARARLCGTGARLCGALCFPVPGGCAAAQHSALAAPTTLPACRCPPRPRPRCPGRPICLPPGGSVRLRLLCALRRAAGAVRVGLALEAATAGTPSASPSPSPPLPPNLPEARAGPARRARRGTSGRGSLKFPMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSATGAVSTDSVLDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQSEYRERVRENLEVGYEVLTIRASDRDSPINANLRYRVLGGAWDVFQLNESSGVVSTRAVLDREEAAEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVGLNTAVLRVQATDRDQGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQDGGRPPLINSSGVVSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADSGENARLHYRLVDTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSPPMSSSTSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSVLTLQARDRDANSVITYQLTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASDGTRSHTAHVLINVTDANTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARITYVIQDPVPQFRIDPDSGTMYTMMELDYENQVAYTLTIMAQDNGIPQKSDTTTLEILILDANDNAPQFLWDFYQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDRGSPTPLSASVEIQVTILDINDNAPMFEKDELELFVEENNPVGSVVAKIRANDPDEGPNAQIMYQIVEGDMRHFFQLDLLNGDLRAMVELDFEVRREYVLVVQATSAPLVSRATVHILLVDQNDNPPVLPDFQILFNNYVTNKSNSFPTGVIGCIPAHDPDVSDSLNYTFVQGNELRLLLLDPATGELQLSRDLDNNRPLEALMEVSVSDGIHSVTAFCTLRVTIITDDMLTNSITVRLENMSQEKFLSPLLALFVEGVAAVLSTTKDDVFVFNVQNDTDVSSNILNVTFSALLPGGVRGQFFPSEDLQEQIYLNRTLLTTISTQRVLPFDDNICLREPCENYMKCVSVLRFDSSAPFLSSTTVLFRPIHPINGLRCRCPPGFTGDYCETEIDLCYSDPCGANGRCRSREGGYTCECFEDFTGEHCEVDARSGRCANGVCKNGGTCVNLLIGGFHCVCPPGEYERPYCEVTTRSFPPQSFVTFRGLRQRFHFTISLTFATQERNGLLLYNGRFNEKHDFIALEIVDEQVQLTFSAGETTTTVAPKVPSGVSDGRWHSVQVQYYNKPNIGHLGLPHGPSGEKMAVVTVDDCDTTMAVRFGKDIGNYSCAAQGTQTGSKKSLDLTGPLLLGGVPNLPEDFPVHNRQFVGCMRNLSVDGKNVDMAGFIANNGTREGCAARRNFCDGRRCQNGGTCVNRWNMYLCECPLRFGGKNCEQAMPHPQLFSGESVVSWSDLNIIISVPWYLGLMFRTRKEDSVLMEATSGGPTSFRLQILNNYLQFEVSHGPSDVESVMLSGLRVTDGEWHHLLIELKNVKEDSEMKHLVTMTLDYGMDQNKADIGGMLPGLTVRSVVVGGASEDKVSVRRGFRGCMQGVRMGGTPTNVATLNMNNALKVRVKDGCDVDDPCTSSPCPPNSRCHDAWEDYSCVCDKGYLGINCVDACHLNPCENMGACVRSPGSPQGYVCECGPSHYGPYCENKLDLPCPRGWWGNPVCGPCHCAVSKGFDPDCNKTNGQCQCKENYYKLLAQDTCLPCDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRCDNPFAEVTTLGCEVIYNGCPKAFEAGIWWPQTKFGQPAAVPCPKGSVGNAVRHCSGEKGWLPPELFNCTTISFVDLRAMNEKLSRNETQVDGARALQLVRALRSATQHTGTLFGNDVRTAYQLLGHVLQHESWQQGFDLAATQDADFHEDVIHSGSALLAPATRAAWEQIQRSEGGTAQLLRRLEGYFSNVARNVRRTYLRPFVIVTANMILAVDIFDKFNFTGARVPRFDTIHEEFPRELESSVSFPADFFRPPEEKEGPLLRPAGRRTTPQTTRPGPGTEREAPISRRRRHPDDAGQFAVALVIIYRTLGQLLPERYDPDRRSLRLPHRPIINTPMVSTLVYSEGAPLPRPLERPVLVEFALLEVEERTKPVCVFWNHSLAVGGTGGWSARGCELLSRNRTHVACQCSHTASFAVLMDISRRENGEVLPLKIVTYAAVSLSLAALLVAFVLLSLVRMLRSNLHSIHKHLAVALFLSQLVFVIGINQTENPFLCTVVAILLHYIYMSTFAWTLVESLHVYRMLTEVRNIDTGPMRFYYVVGWGIPAIVTGLAVGLDPQGYGNPDFCWLSLQDTLIWSFAGPIGAVIIINTVTSVLSAKVSCQRKHHYYGKKGIVSLLRTAFLLLLLISATWLLGLLAVNRDALSFHYLFAIFSGLQGPFVLLFHCVLNQEVRKHLKGVLGGRKLHLEDSATTRATLLTRSLNCNTTFGDGPDMLRTDLGESTASLDSIVRDEGIQKLGVSSGLVRGSHGEPDASLMPRSCKDPPGHDSDSDSELSLDEQSSSYASSHSSDSEDDGVGAEEKWDPARGAVHSTPKGDAVANHVPAGWPDQSLAESDSEDPSGKPRLKVETKVSVELHREEQGSHRGEYPPDQESGGAARLASSQPPEQRKGILKNKVTYPPPLTLTEQTLKGRLREKLADCEQSPTSSRTSSLGSGGPDCAITVKSPGREPGRDHLNGVAMNVRTGSAQADGSDSEKP
"
     sig_peptide     1..75
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
     misc_feature    748..1047
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Cadherin tandem repeat domain; Region:
                     Cadherin_repeat; cd11304"
                     /db_xref="CDD:206637"
     misc_feature    order(766..771,934..936,940..942,1033..1035,1039..1044)
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:206637"
     misc_feature    1069..1365
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Cadherin tandem repeat domain; Region:
                     Cadherin_repeat; cd11304"
                     /db_xref="CDD:206637"
     misc_feature    order(1090..1095,1246..1248,1252..1254,1351..1353,
                     1357..1362)
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:206637"
     misc_feature    1390..1683
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Cadherin tandem repeat domain; Region:
                     Cadherin_repeat; cd11304"
                     /db_xref="CDD:206637"
     misc_feature    order(1408..1413,1567..1569,1573..1575,1669..1671,
                     1675..1680)
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:206637"
     misc_feature    1705..2049
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Cadherin tandem repeat domain; Region:
                     Cadherin_repeat; cd11304"
                     /db_xref="CDD:206637"
     misc_feature    order(1726..1731,1936..1938,1942..1944,2035..2037,
                     2041..2046)
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:206637"
     misc_feature    2071..2355
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Cadherin tandem repeat domain; Region:
                     Cadherin_repeat; cd11304"
                     /db_xref="CDD:206637"
     misc_feature    order(2092..2097,2251..2253,2257..2259,2341..2343,
                     2347..2352)
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:206637"
     misc_feature    2377..2664
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Cadherin tandem repeat domain; Region:
                     Cadherin_repeat; cd11304"
                     /db_xref="CDD:206637"
     misc_feature    order(2398..2403,2551..2553,2557..2559,2650..2652,
                     2656..2661)
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:206637"
     misc_feature    2689..2985
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Cadherin tandem repeat domain; Region:
                     Cadherin_repeat; cd11304"
                     /db_xref="CDD:206637"
     misc_feature    order(2707..2712,2869..2871,2875..2877,2971..2973,
                     2977..2982)
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:206637"
     misc_feature    3007..3291
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Cadherin tandem repeat domain; Region:
                     Cadherin_repeat; cd11304"
                     /db_xref="CDD:206637"
     misc_feature    order(3028..3033,3187..3189,3193..3195,3277..3279,
                     3283..3288)
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:206637"
     misc_feature    3349..3594
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Cadherin tandem repeat domain; Region:
                     Cadherin_repeat; cd11304"
                     /db_xref="CDD:206637"
     misc_feature    4087..4197
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Calcium-binding EGF-like domain, present in a large
                     number of membrane-bound and extracellular (mostly animal)
                     proteins. Many of these proteins require calcium for their
                     biological function and calcium-binding sites have been
                     found to be located at the...; Region: EGF_CA; cd00054"
                     /db_xref="CDD:28936"
     misc_feature    order(4087..4089,4096..4098,4138..4140)
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:28936"
     misc_feature    4219..4323
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Calcium-binding EGF-like domain, present in a large
                     number of membrane-bound and extracellular (mostly animal)
                     proteins. Many of these proteins require calcium for their
                     biological function and calcium-binding sites have been
                     found to be located at the...; Region: EGF_CA; cd00054"
                     /db_xref="CDD:28936"
     misc_feature    4330..4881
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Laminin G domain; Laminin G-like domains are
                     usually Ca++ mediated receptors that can have binding
                     sites for steroids, beta1 integrins, heparin, sulfatides,
                     fibulin-1, and alpha-dystroglycans. Proteins that contain
                     LamG domains serve a variety of...; Region: LamG; cd00110"
                     /db_xref="CDD:29010"
     misc_feature    4951..5055
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Calcium-binding EGF-like domain, present in a large
                     number of membrane-bound and extracellular (mostly animal)
                     proteins. Many of these proteins require calcium for their
                     biological function and calcium-binding sites have been
                     found to be located at the...; Region: EGF_CA; cd00054"
                     /db_xref="CDD:28936"
     misc_feature    order(4954..4956,4996..4998)
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:28936"
     misc_feature    5080..5538
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Laminin G domain; Laminin G-like domains are
                     usually Ca++ mediated receptors that can have binding
                     sites for steroids, beta1 integrins, heparin, sulfatides,
                     fibulin-1, and alpha-dystroglycans. Proteins that contain
                     LamG domains serve a variety of...; Region: LamG; cd00110"
                     /db_xref="CDD:29010"
     misc_feature    5611..5724
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Calcium-binding EGF-like domain, present in a large
                     number of membrane-bound and extracellular (mostly animal)
                     proteins. Many of these proteins require calcium for their
                     biological function and calcium-binding sites have been
                     found to be located at the...; Region: EGF_CA; cd00054"
                     /db_xref="CDD:28936"
     misc_feature    order(5611..5613,5620..5622,5665..5667)
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:28936"
     misc_feature    5722..5838
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Calcium-binding EGF-like domain, present in a large
                     number of membrane-bound and extracellular (mostly animal)
                     proteins. Many of these proteins require calcium for their
                     biological function and calcium-binding sites have been
                     found to be located at the...; Region: EGF_CA; cd00054"
                     /db_xref="CDD:28936"
     misc_feature    order(5728..5730,5770..5772)
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:28936"
     misc_feature    6004..>6120
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Laminin-type epidermal growth factor-like domain;
                     laminins are the major noncollagenous components of
                     basement membranes that mediate cell adhesion, growth
                     migration, and differentiation; the laminin-type epidermal
                     growth factor-like module occurs in...; Region: EGF_Lam;
                     cd00055"
                     /db_xref="CDD:28937"
     misc_feature    6007..6144
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Laminin-type epidermal growth factor-like domai;
                     Region: EGF_Lam; smart00180"
                     /db_xref="CDD:197558"
     misc_feature    order(6007..6009,6013..6015,6043..6045,6064..6066,
                     6070..6072,6097..6099)
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="EGF-like motif; other site"
                     /db_xref="CDD:28937"
     misc_feature    6154..6339
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Domain present in hormone receptors; Region: HormR;
                     smart00008"
                     /db_xref="CDD:197465"
     misc_feature    6364..7146
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="Domain of unknown function (DUF3497); Region:
                     DUF3497; pfam12003"
                     /db_xref="CDD:204805"
     misc_feature    7219..7380
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="G-protein-coupled receptor proteolytic site domain;
                     Region: GPS; smart00303"
                     /db_xref="CDD:197639"
     misc_feature    7396..8091
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /note="7 transmembrane receptor (Secretin family); Region:
                     7tm_2; pfam00002"
                     /db_xref="CDD:200919"
     misc_feature    7408..7470
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9NYQ6.1);
                     transmembrane region"
     misc_feature    7504..7566
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9NYQ6.1);
                     transmembrane region"
     misc_feature    7582..7644
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9NYQ6.1);
                     transmembrane region"
     misc_feature    7717..7779
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9NYQ6.1);
                     transmembrane region"
     misc_feature    7834..7896
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9NYQ6.1);
                     transmembrane region"
     misc_feature    7966..8028
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9NYQ6.1);
                     transmembrane region"
     misc_feature    8050..8112
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9NYQ6.1);
                     transmembrane region"
     misc_feature    8290..8292
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q9NYQ6.1); phosphorylation site"
     misc_feature    8599..8601
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     exon            1..3544
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     variation       355
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:926287"
     variation       1666
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:11575871"
     exon            3545..4183
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            4184..4406
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            4407..4522
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            4523..4611
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            4612..4769
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            4770..4933
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            4934..5059
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            5060..5226
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            5227..5412
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            5413..5526
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            5527..5701
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            5702..5843
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            5844..5964
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            5965..6148
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            6149..6250
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            6251..6345
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            6346..6555
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            6556..6739
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            6740..6883
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            6884..7088
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            7089..7256
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            7257..7383
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            7384..7584
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            7585..7759
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            7760..7872
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            7873..7952
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            7953..8079
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            8080..8205
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            8206..8300
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            8301..8404
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            8405..8554
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            8555..8779
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            8780..9035
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     exon            9036..11389
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /inference="alignment:Splign:1.39.8"
     variation       10247
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201772740"
     STS             11044..11173
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /standard_name="RH93715"
                     /db_xref="UniSTS:92944"
     variation       11132
                     /gene="CELSR1"
                     /gene_synonym="CDHF9; FMI2; HFMI2; ME2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:15023"
ORIGIN      
atggcgccgccgccgccgcccgtgctgcccgtgctgctgctcctggccgccgccgccgccctgccggcgatggggctgcgagcggccgcctgggagccgcgcgtacccggcgggacccgcgccttcgccctccggcccggctgtacctacgcggtgggcgccgcttgcacgccccgggcgccgcgggagctgctggacgtgggccgcgatgggcggctggcaggacgtcggcgcgtctcgggcgcggggcgcccgctgccgctgcaagtccgcttggtggcccgcagtgccccgacggcgctgagccgccgcctgcgggcgcgcacgcaccttcccggctgcggagcccgtgcccggctctgcggaaccggtgcccggctctgcggggcgctctgcttccccgtccccggcggctgcgcggccgcgcagcattcggcgctcgcagctccgaccaccttacccgcctgccgctgcccgccgcgccccaggccccgctgtcccggccgtcccatctgcctgccgccgggcggctcggtccgcctgcgtctgctgtgcgccctgcggcgcgcggctggcgccgtccgggtgggactggcgctggaggccgccaccgcggggacgccctccgcgtcgccatccccatcgccgcccctgccgccgaacttgcccgaagcccgggcggggccggcgcgacgggcccggcggggcacgagcggcagagggagcctgaagtttccgatgcccaactaccaggtggcgttgtttgagaacgaaccggcgggcaccctcatcctccagctgcacgcgcactacaccatcgagggcgaggaggagcgcgtgagctattacatggaggggctgttcgacgagcgctcccggggctacttccgaatcgactctgccacgggcgccgtgagcacggacagcgtactggaccgcgagaccaaggagacgcacgtcctcagggtgaaagccgtggactacagtacgccgccgcgctcggccaccacctacatcactgtcttggtcaaagacaccaacgaccacagcccggtcttcgagcagtcggagtaccgcgagcgcgtgcgggagaacctggaggtgggctacgaggtgctgaccatccgcgccagcgaccgcgactcgcccatcaacgccaacttgcgttaccgcgtgttggggggcgcgtgggacgtcttccagctcaacgagagctctggcgtggtgagcacacgggcggtgctggaccgggaggaggcggccgagtaccagctcctggtggaggccaacgaccaggggcgcaatccgggcccgctcagtgccacggccaccgtgtacatcgaggtggaggacgagaacgacaactacccccagttcagcgagcagaactacgtggtccaggtgcccgaggacgtggggctcaacacggctgtgctgcgagtgcaggccacggaccgggaccagggccagaacgcggccattcactacagcatcctcagcgggaacgtggccggccagttctacctgcactcgctgagcgggatcctggatgtgatcaaccccttggatttcgaggatgtccagaaatactcgctgagcattaaggcccaggatgggggccggcccccgctcatcaattcttcaggggtggtgtctgtgcaggtgctggatgtcaacgacaacgagcctatctttgtgagcagccccttccaggccacggtgctggagaatgtgcccctgggctaccccgtggtgcacattcaggcggtggacgcggactctggagagaacgcccggctgcactatcgcctggtggacacggcctccacctttctggggggcggcagcgctgggcctaagaatcctgcccccacccctgacttccccttccagatccacaacagctccggttggatcacagtgtgtgccgagctggaccgcgaggaggtggagcactacagcttcggggtggaggcggtggaccacggctcgccccccatgagctcctccaccagcgtgtccatcacggtgctggacgtgaatgacaacgacccggtgttcacgcagcccacctacgagcttcgtctgaatgaggatgcggccgtggggagcagcgtgctgaccctgcaggcccgcgaccgtgacgccaacagtgtgattacctaccagctcacaggcggcaacacccggaaccgctttgcactcagcagccagagagggggcggcctcatcaccctggcgctacctctggactacaagcaggagcagcagtacgtgctggcggtgacagcatccgacggcacacggtcgcacactgcgcatgtcctaatcaacgtcactgatgccaacacccacaggcctgtctttcagagctcccattacacagtgagtgtcagtgaggacaggcctgtgggcacctccattgctaccctcagtgccaacgatgaggacacaggagagaatgcccgcatcacctacgtgattcaggaccccgtgccgcagttccgcattgaccccgacagtggcaccatgtacaccatgatggagctggactatgagaaccaggtcgcctacacgctgaccatcatggcccaggacaacggcatcccgcagaaatcagacaccaccaccctagagatcctcatcctcgatgccaatgacaatgcaccccagttcctgtgggatttctaccagggttccatctttgaggatgctccaccctcgaccagcatcctccaggtctctgccacggaccgggactcaggtcccaatgggcgtctgctgtacaccttccagggtggggacgacggcgatggggacttctacatcgagcccacgtccggtgtgattcgcacccagcgccggctggaccgggagaatgtggccgtgtacaacctttgggctctggctgtggatcggggcagtcccactccccttagcgcctcggtagaaatccaggtgaccatcttggacattaatgacaatgcccccatgtttgagaaggacgaactggagctgtttgttgaggagaacaacccagtggggtcggtggtggcaaagattcgtgctaacgaccctgatgaaggccctaatgcccagatcatgtatcagattgtggaaggggacatgcggcatttcttccagctggacctgctcaacggggacctgcgtgccatggtggagctggactttgaggtccggcgggagtatgtgctggtggtgcaggccacgtcggctccgctggtgagccgagccacggtgcacatccttctcgtggaccagaatgacaacccgcctgtgctgcccgacttccagatcctcttcaacaactatgtcaccaacaagtccaacagtttccccaccggcgtgatcggctgcatcccggcccatgaccccgacgtgtcagacagcctcaactacaccttcgtgcagggcaacgagctgcgcctgttgctgctggaccccgccacgggcgaactgcagctcagccgcgacctggacaacaaccggccgctggaggcgctcatggaggtgtctgtgtctgatggcatccacagcgtcacggccttctgcaccctgcgtgtcaccatcatcacggacgacatgctgaccaacagcatcactgtccgcctggagaacatgtcccaggagaagttcctgtccccgctgctggccctcttcgtggagggggtggccgccgtgctgtccaccaccaaggacgacgtcttcgtcttcaacgtccagaacgacaccgacgtcagctccaacatcctgaacgtgaccttctcggcgctgctgcctggcggcgtccgcggccagttcttcccgtcggaggacctgcaggagcagatctacctgaatcggacgctgctgaccaccatctccacgcagcgcgtgctgcccttcgacgacaacatctgcctgcgcgagccctgcgagaactacatgaagtgcgtgtccgttctgcgattcgacagctccgcgcccttcctcagctccaccaccgtgctcttccggcccatccaccccatcaacggcctgcgctgccgctgcccgcccggcttcaccggcgactactgcgagacggagatcgacctctgctactccgacccgtgcggcgccaacggccgctgccgcagccgcgagggcggctacacctgcgagtgcttcgaggacttcactggagagcactgtgaggtggatgcccgctcaggccgctgtgccaacggggtgtgcaagaacgggggcacctgcgtgaacctgctcatcggcggcttccactgcgtgtgtcctcctggcgagtatgagaggccctactgtgaggtgaccaccaggagcttcccgccccagtccttcgtcaccttccggggcctgagacagcgcttccacttcaccatctccctcacgtttgccactcaggaaaggaacggcttgcttctctacaacggccgcttcaatgagaagcacgacttcatcgccctggagatcgtggacgagcaggtgcagctcaccttctctgcaggcgagacaacaacgaccgtggcaccgaaggttcccagtggtgtgagtgacgggcggtggcactctgtgcaggtgcagtactacaacaagcccaatattggccacctgggcctgccccatgggccgtccggggaaaagatggccgtggtgacagtggatgattgtgacacaaccatggctgtgcgctttggaaaggacatcgggaactacagctgcgctgcccagggcactcagaccggctccaagaagtccctggatctgaccggccctctactcctggggggtgtccccaacctgccagaagacttcccagtgcacaaccggcagttcgtgggctgcatgcggaacctgtcagtcgacggcaaaaatgtggacatggccggattcatcgccaacaatggcacccgggaaggctgcgctgctcggaggaacttctgcgatgggaggcggtgtcagaatggaggcacctgtgtcaacaggtggaatatgtatctgtgtgagtgtccactccgattcggcgggaagaactgtgagcaagccatgcctcacccccagctcttcagcggtgagagcgtcgtgtcctggagtgacctgaacatcatcatctctgtgccctggtacctggggctcatgttccggacccggaaggaggacagcgttctgatggaggccaccagtggtgggcccaccagctttcgcctccagatcctgaacaactacctccagtttgaggtgtcccacggcccctccgatgtggagtccgtgatgctgtccgggttgcgggtgaccgacggggagtggcaccacctgctgatcgagctgaagaatgttaaggaggacagtgagatgaagcacctggtcaccatgaccttggactatgggatggaccagaacaaggcagatatcgggggcatgcttcccgggctgacggtaaggagcgtggtggtcggaggcgcctctgaagacaaggtctccgtgcgccgtggattccgaggctgcatgcagggagtgaggatgggggggacgcccaccaacgtcgccaccctgaacatgaacaacgcactcaaggtcagggtgaaggacggctgtgatgtggacgacccctgtacctcgagcccctgtccccccaatagccgctgccacgacgcctgggaggactacagctgcgtctgtgacaaagggtaccttggaataaactgtgtggatgcctgtcacctgaacccctgcgagaacatgggggcctgcgtgcgctcccccggctccccgcagggctacgtgtgcgagtgtgggcccagtcactacgggccgtactgtgagaacaaactcgaccttccgtgccccagaggctggtgggggaaccccgtctgtggaccctgccactgtgccgtcagcaaaggctttgatcccgactgtaataagaccaacggccagtgccaatgcaaggagaattactacaagctcctagcccaggacacctgtctgccctgcgactgcttcccccatggctcccacagccgcacttgcgacatggccaccgggcagtgtgcctgcaagcccggcgtcatcggccgccagtgcaaccgctgcgacaacccgtttgccgaggtcaccacgctcggctgtgaagtgatctacaatggctgtcccaaagcatttgaggccggcatctggtggccacagaccaagttcgggcagccggctgcggtgccatgccctaagggatccgttggaaatgcggtccgacactgcagcggggagaagggctggctgcccccagagctctttaactgtaccaccatctccttcgtggacctcagggccatgaatgagaagctgagccgcaatgagacgcaggtggacggcgccagggccctgcagctggtgagggcgctgcgcagtgctacacagcacacgggcacgctctttggcaatgacgtgcgcacggcctaccagctgctgggccacgtccttcagcacgagagctggcagcagggcttcgacctggcagccacgcaggacgccgactttcacgaggacgtcatccactcgggcagcgccctcctggccccagccaccagggcggcgtgggagcagatccagcggagcgagggcggcacggcacagctgctccggcgcctcgagggctacttcagcaacgtggcacgcaacgtgcggcggacgtacctgcggcccttcgtcatcgtcaccgccaacatgattcttgctgtcgacatctttgacaagttcaactttacgggagccagggtcccgcgattcgacaccatccatgaagagttccccagggagctggagtcctccgtctccttcccagccgacttcttcagaccacctgaagaaaaagaaggccccctgctgaggccggctggccggaggaccaccccgcagaccacgcgcccggggcctggcaccgagagggaggccccgatcagcaggcggaggcgacaccctgatgacgctggccagttcgccgtcgctctggtcatcatttaccgcaccctggggcagctcctgcccgagcgctacgaccccgaccgtcgcagcctccggttgcctcaccggcccatcattaataccccgatggtgagcacgctggtgtacagcgagggggctccgctcccgagacccctggagaggcccgtcctggtggagttcgccctgctggaggtggaggagcgaaccaagcctgtctgcgtgttctggaaccactccctggccgttggtgggacgggagggtggtctgcccggggctgcgagctcctgtccaggaaccggacacatgtcgcctgccagtgcagccacacagccagctttgcggtgctcatggatatctccaggcgtgagaacggggaggtcctgcctctgaagattgtcacctatgccgctgtgtccttgtcactggcagccctgctggtggccttcgtcctcctgagcctggtccgcatgctgcgctccaacctgcacagcattcacaagcacctcgccgtggcgctcttcctctctcagctggtgttcgtgattgggatcaaccagacggaaaacccgtttctgtgcacagtggttgccatcctcctccactacatctacatgagcacctttgcctggaccctcgtggagagcctgcatgtctaccgcatgctgaccgaggtgcgcaacatcgacacggggcccatgcggttctactacgtcgtgggctggggcatcccggccattgtcacaggactggcggtcggcctggacccccagggctacgggaaccccgacttctgctggctgtcgcttcaagacaccctgatttggagctttgcggggcccatcggagctgttataatcatcaacacagtcacttctgtcctatctgcaaaggtttcctgccaaagaaagcaccattattatgggaaaaaagggatcgtctccctgctgaggaccgcattcctcctgctgctgctcatcagcgccacctggctgctggggctgctggctgtgaaccgcgatgcactgagctttcactacctcttcgccatcttcagcggcttacagggccccttcgtcctccttttccactgcgtgctcaaccaggaggtccggaagcacctgaagggcgtgctcggcgggaggaagctgcacctggaggactccgccaccaccagggccaccctgctgacgcgctccctcaactgcaacaccaccttcggtgacgggcctgacatgctgcgcacagacttgggcgagtccaccgcctcgctggacagcatcgtcagggatgaagggatccagaagctcggcgtgtcctctgggctggtgaggggcagccacggagagccagacgcgtccctcatgcccaggagctgcaaggatccccctggccacgattccgactcagatagcgagctgtccctggatgagcagagcagctcttacgcctcctcacactcgtcagacagcgaggacgatggggtgggagctgaggaaaaatgggacccggccaggggcgccgtccacagcacccccaaaggggacgctgtggccaaccacgttccggccggctggcccgaccagagcctggctgagagtgacagtgaggaccccagcggcaagccccgcctgaaggtggagaccaaggtcagcgtggagctgcaccgcgaggagcagggcagtcaccgtggagagtaccccccggaccaggagagcgggggcgcagccaggcttgctagcagccagcccccagagcagaggaaaggcatcttgaaaaataaagtcacctacccgccgccgctgacgctgacggagcagacgctgaagggccggctccgggagaagctggccgactgtgagcagagccccacatcctcgcgcacgtcttccctgggctctggcggccccgactgcgccatcacagtcaagagccctgggagggagccggggcgtgaccacctcaacggggtggccatgaatgtgcgcactgggagcgcccaggccgatggctccgactctgagaaaccgtgaggcaagcccgtcaccccacacaggctgcggcatcaccctcagaccttggagcccaaggggccactgcccttgaagtggagtgggcccagagtgtggcggtccccatggtggcagccccccgactgatcatccagacacaaaggtcttggttctcccaggagctcagggcctgtcagacctggtgacaagtgccaaaggccacaggcatgagggaggcgtggaccactgggccagcaccgctgagtcctaagactgcagtcaaagccagaactgagaggggaccccagactgggcccagaggctggccagagttcaggaacgccgggcacagaccaaagaccgcggtccagccccgcccaggcgggcatctcatggcagtgcggacccgtggctggcagcccgggcagtcctttgcaaaggcaccccttgtcttaaaatcacttcgctatgtgggaaaggtggagatacttttatatatttgtatgggactctgaggaggtgcaacctgtatatatattgcattcgtgctgactttgttatcccgagagatccatgcaatgatctcttgctgtcttctctgtcaagattgcacagttgtacttgaatctggcatgtgttgacgaaactggtgccccagcagatcaaaggtgggaaatacgtcagcagtggggctaaaaccaagcggctagaagccctacagctgccttcggccaggaagtgaggatggtgtgggccctccccgccggccccctgggtccccagtgttcgctgtgtgtgcgtttgtcctctgctgccatctgccccggctgtgtgaattcaagacagggcagtgcagcactaggcaggtgtgaggagccctgctgaggtcactgtggggcacggttgccacacggctgtcatttttcacctggtcattctgtgaccaccaccccctcccctcaccgcctcccaggtggcccgggagctgcaggtggggatggctttgtcctttgctcctgctccccgtgggacctgggaccttaaagcgttgcaggttcctgatttggacagaggtgtggggccttccaggccgttacatacctcctgccaattctctaactctctgagactgcgaggatctccaggcagggttctcccctctggagtctgaccaattacttcattttgcttcaaatggccaattgtgcagagggacaaagccacagccacactcttcaacggttaccaaactgtttttggaaattcacaccaaggtcgggcccactgcaggcagctggcacagcgtggcccgaggggctgtggaacgggtcccggaactgtcagacatgtttgattttagcgtttcctttgttcttcaaatcaggtgcccaaataagtgatcagcacagctgcttccaaataggagaaaccataaaataggatgaaaatcaagtaaaatgcaaagatgtccacactgttttaaacttgaccctgatgaaaatgtgagcactgttagcagatgcctatgggagaggaaaagcgtatctgaaaatggtccaggacaggaggatgaaatgagatcccagagtcctcacacctgaatgaattatacatgtgccttaccaggtgagtggtctttcgaagataaaaaactctagtccctttaaacgtttgcccctggcgtttcctaagtacgaaaaggtttttaagtcttcgaacagtctcctttcatgactttaacaggattctgccccctgaggtgtaatttttttgttctatttttttccacgtactccacagccaacatcacgaggtgtaatttttaatttgatcagaactgttaccaaaaaacaactgtcagttttattgagatgggaaaaatgtaaacctatttttattacttaagactttatgggagagattagacactggaggtttttaacagaacgtgtatttattaatgttcaaaacactggaattacaaatgagaagagtctacaataaattaagatttttgaatttgtacttctgcggtgctggtttttctccacaaacacccccgcccctccccatgcccagggtggccgtggaagggacggtttacggacgtgcagctgagctgtccgtgtcccatgctccctcagccagtggaacgtgccggaactttttgtccattccctagtaggcctgccacagcctagatgggcagtttttgtctttcaccaaatttgaggactttttttttttgccattatttcttcagttttcttttcttgcactgatctttctcctctccttctgtgactccagtgactcagacgttagacctcttgatgttttcccactggtccctgaggctctgttc
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:9620 -> Molecular function: GO:0004888 [transmembrane signaling receptor activity] evidence: NAS
            GeneID:9620 -> Molecular function: GO:0004930 [G-protein coupled receptor activity] evidence: NAS
            GeneID:9620 -> Molecular function: GO:0005509 [calcium ion binding] evidence: IEA
            GeneID:9620 -> Molecular function: GO:0046983 [protein dimerization activity] evidence: NAS
            GeneID:9620 -> Biological process: GO:0001736 [establishment of planar polarity] evidence: ISS
            GeneID:9620 -> Biological process: GO:0001764 [neuron migration] evidence: IEA
            GeneID:9620 -> Biological process: GO:0001843 [neural tube closure] evidence: ISS
            GeneID:9620 -> Biological process: GO:0001942 [hair follicle development] evidence: IEA
            GeneID:9620 -> Biological process: GO:0007156 [homophilic cell adhesion] evidence: IEA
            GeneID:9620 -> Biological process: GO:0007186 [G-protein coupled receptor signaling pathway] evidence: NAS
            GeneID:9620 -> Biological process: GO:0007218 [neuropeptide signaling pathway] evidence: IEA
            GeneID:9620 -> Biological process: GO:0007266 [Rho protein signal transduction] evidence: IEA
            GeneID:9620 -> Biological process: GO:0007417 [central nervous system development] evidence: NAS
            GeneID:9620 -> Biological process: GO:0007417 [central nervous system development] evidence: TAS
            GeneID:9620 -> Biological process: GO:0007626 [locomotory behavior] evidence: IEA
            GeneID:9620 -> Biological process: GO:0009952 [anterior/posterior pattern specification] evidence: IEA
            GeneID:9620 -> Biological process: GO:0032956 [regulation of actin cytoskeleton organization] evidence: IEA
            GeneID:9620 -> Biological process: GO:0042060 [wound healing] evidence: IEA
            GeneID:9620 -> Biological process: GO:0042249 [establishment of planar polarity of embryonic epithelium] evidence: IEA
            GeneID:9620 -> Biological process: GO:0042472 [inner ear morphogenesis] evidence: IEA
            GeneID:9620 -> Biological process: GO:0045176 [apical protein localization] evidence: IEA
            GeneID:9620 -> Biological process: GO:0048105 [establishment of body hair planar orientation] evidence: IEA
            GeneID:9620 -> Biological process: GO:0060488 [orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis] evidence: IEA
            GeneID:9620 -> Biological process: GO:0060489 [planar dichotomous subdivision of terminal units involved in lung branching morphogenesis] evidence: IEA
            GeneID:9620 -> Biological process: GO:0060490 [lateral sprouting involved in lung morphogenesis] evidence: IEA
            GeneID:9620 -> Biological process: GO:0090179 [planar cell polarity pathway involved in neural tube closure] evidence: IEA
            GeneID:9620 -> Biological process: GO:0090251 [protein localization involved in establishment of planar polarity] evidence: IEA
            GeneID:9620 -> Cellular component: GO:0005887 [integral to plasma membrane] evidence: TAS
            GeneID:9620 -> Cellular component: GO:0016021 [integral to membrane] evidence: TAS

by @meso_cacase at DBCLS
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