LOCUS       NM_014212               2100 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens homeobox C11 (HOXC11), mRNA.
ACCESSION   NM_014212
VERSION     NM_014212.3  GI:84043954
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2100)
  AUTHORS   McIlroy,M., McCartan,D., Early,S., O Gaora,P., Pennington,S.,
            Hill,A.D. and Young,L.S.
  TITLE     Interaction of developmental transcription factor HOXC11 with
            steroid receptor coactivator SRC-1 mediates resistance to endocrine
            therapy in breast cancer [corrected]
  JOURNAL   Cancer Res. 70 (4), 1585-1594 (2010)
   PUBMED   20145129
  REMARK    GeneRIF: HOXC11 and SRC-1 cooperate to regulate expression of the
            calcium-binding protein S100beta in resistant breast cancer cells.
            Erratum:[Cancer Res. 2010 Apr 15;70(8):3413]
REFERENCE   2  (bases 1 to 2100)
  AUTHORS   Zhang,X., Hamada,J., Nishimoto,A., Takahashi,Y., Murai,T., Tada,M.
            and Moriuchi,T.
  TITLE     HOXC6 and HOXC11 increase transcription of S100beta gene in
            BrdU-induced in vitro differentiation of GOTO neuroblastoma cells
            into Schwannian cells
  JOURNAL   J. Cell. Mol. Med. 11 (2), 299-306 (2007)
   PUBMED   17488478
  REMARK    GeneRIF: HOXC11 increases transcription of S100beta gene in
            BrdU-induced in vitro differentiation of GOTO neuroblastoma cells
            into Schwann cells.
REFERENCE   3  (bases 1 to 2100)
  AUTHORS   Lamesch,P., Li,N., Milstein,S., Fan,C., Hao,T., Szabo,G., Hu,Z.,
            Venkatesan,K., Bethel,G., Martin,P., Rogers,J., Lawlor,S.,
            McLaren,S., Dricot,A., Borick,H., Cusick,M.E., Vandenhaute,J.,
            Dunham,I., Hill,D.E. and Vidal,M.
  TITLE     hORFeome v3.1: a resource of human open reading frames representing
            over 10,000 human genes
  JOURNAL   Genomics 89 (3), 307-315 (2007)
   PUBMED   17207965
REFERENCE   4  (bases 1 to 2100)
  AUTHORS   Kosaki,K., Kosaki,R., Suzuki,T., Yoshihashi,H., Takahashi,T.,
            Sasaki,K., Tomita,M., McGinnis,W. and Matsuo,N.
  TITLE     Complete mutation analysis panel of the 39 human HOX genes
  JOURNAL   Teratology 65 (2), 50-62 (2002)
   PUBMED   11857506
REFERENCE   5  (bases 1 to 2100)
  AUTHORS   Mitchelmore,C., Troelsen,J.T., Sjostrom,H. and Noren,O.
  TITLE     The HOXC11 homeodomain protein interacts with the lactase-phlorizin
            hydrolase promoter and stimulates HNF1alpha-dependent transcription
  JOURNAL   J. Biol. Chem. 273 (21), 13297-13306 (1998)
   PUBMED   9582375
REFERENCE   6  (bases 1 to 2100)
  AUTHORS   Flagiello,D., Gibaud,A., Dutrillaux,B., Poupon,M.F. and Malfoy,B.
  TITLE     Distinct patterns of all-trans retinoic acid dependent expression
            of HOXB and HOXC homeogenes in human embryonal and small-cell lung
            carcinoma cell lines
  JOURNAL   FEBS Lett. 415 (3), 263-267 (1997)
   PUBMED   9357979
REFERENCE   7  (bases 1 to 2100)
  AUTHORS   Apiou,F., Flagiello,D., Cillo,C., Malfoy,B., Poupon,M.F. and
            Dutrillaux,B.
  TITLE     Fine mapping of human HOX gene clusters
  JOURNAL   Cytogenet. Cell Genet. 73 (1-2), 114-115 (1996)
   PUBMED   8646877
REFERENCE   8  (bases 1 to 2100)
  AUTHORS   Acampora,D., D'Esposito,M., Faiella,A., Pannese,M., Migliaccio,E.,
            Morelli,F., Stornaiuolo,A., Nigro,V., Simeone,A. and Boncinelli,E.
  TITLE     The human HOX gene family
  JOURNAL   Nucleic Acids Res. 17 (24), 10385-10402 (1989)
   PUBMED   2574852
REFERENCE   9  (bases 1 to 2100)
  AUTHORS   Rabin,M., Ferguson-Smith,A., Hart,C.P. and Ruddle,F.H.
  TITLE     Cognate homeo-box loci mapped on homologous human and mouse
            chromosomes
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 83 (23), 9104-9108 (1986)
   PUBMED   2878432
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC012531.11, AJ000041.1 and
            BC001543.1.
            On Dec 29, 2005 this sequence version replaced gi:24497534.
            
            Summary: This gene belongs to the homeobox family of genes. The
            homeobox genes encode a highly conserved family of transcription
            factors that play an important role in morphogenesis in all
            multicellular organisms. Mammals possess four similar homeobox gene
            clusters, HOXA, HOXB, HOXC and HOXD, which are located on different
            chromosomes and consist of 9 to 11 genes arranged in tandem. This
            gene is one of several homeobox HOXC genes located in a cluster on
            chromosome 12. The product of this gene binds to a promoter element
            of the lactase-phlorizin hydrolase. It also may play a role in
            early intestinal development. An alternatively spliced variant
            encoding a shorter isoform has been described but its full-length
            nature has not been determined. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC001543.1, AK291946.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025095 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-152               AC012531.11        110730-110881
            153-1383            AJ000041.1         81-1311
            1384-1779           BC001543.1         1365-1760
            1780-2100           BC001543.1         1762-2082
FEATURES             Location/Qualifiers
     source          1..2100
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q13.3"
     gene            1..2100
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /note="homeobox C11"
                     /db_xref="GeneID:3227"
                     /db_xref="HGNC:5123"
                     /db_xref="HPRD:09275"
                     /db_xref="MIM:605559"
     exon            1..798
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /inference="alignment:Splign:1.39.8"
     variation       5
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:187224438"
     misc_feature    69..71
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /note="upstream in-frame stop codon"
     variation       77
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372792014"
     variation       86
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372496237"
     variation       99
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374141798"
     variation       104
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:377372195"
     variation       110
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200921214"
     CDS             117..1031
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /note="homeo box C11; homeobox protein Hox-3H"
                     /codon_start=1
                     /product="homeobox protein Hox-C11"
                     /protein_id="NP_055027.1"
                     /db_xref="GI:7657166"
                     /db_xref="CCDS:CCDS8867.1"
                     /db_xref="GeneID:3227"
                     /db_xref="HGNC:5123"
                     /db_xref="HPRD:09275"
                     /db_xref="MIM:605559"
                     /translation="

MFNSVNLGNFCSPSRKERGADFGERGSCASNLYLPSCTYYMPEFSTVSSFLPQAPSRQISYPYSAQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECLPPSTVTEILMKNEGSYGGHHHPSAPHATPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDPPAEPPCSGKGEAKGEPEAPPASGLASRAEAGAEAEAEEENTNPSSSGSAHSVAKEPAKGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDRLQYFSGNPLL

"
     misc_feature    240..668
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /note="Protein of unknown function (DUF3528); Region:
                     DUF3528; pfam12045"
                     /db_xref="CDD:152480"
     misc_feature    813..983
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /note="Homeodomain;  DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:28970"
     misc_feature    order(813..827,831..833,882..884,900..902,939..941,
                     945..950,957..962,966..974,978..983)
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:28970"
     misc_feature    order(819..821,828..830,948..950,957..962,969..971)
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:28970"
     variation       128
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:201521088"
     variation       134
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:34028255"
     variation       152
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:4759315"
     variation       164
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141903332"
     variation       173
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146084910"
     variation       190
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199765463"
     variation       214
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374603975"
     variation       259
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:17849492"
     variation       280
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367629889"
     variation       301
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374695143"
     variation       307
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201705157"
     variation       325..326
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:35477816"
     variation       357
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367923255"
     variation       374
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:372124938"
     variation       404
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:201200152"
     variation       420
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375478114"
     variation       471
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:34528355"
     variation       475
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369638511"
     variation       480
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:372700015"
     variation       490
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140041271"
     variation       500
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:143575026"
     variation       501
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202055341"
     variation       504
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34652380"
     variation       505
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:146287117"
     variation       521
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:139414813"
     variation       522
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:149946964"
     variation       527
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:71455261"
     variation       541
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145009440"
     variation       569
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:377285184"
     variation       587
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:377159561"
     variation       603
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200941742"
     variation       657
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370804226"
     variation       781
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:12427129"
     exon            799..2055
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /inference="alignment:Splign:1.39.8"
     STS             804..1138
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /standard_name="Hoxc11"
                     /db_xref="UniSTS:536478"
     variation       842
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:201625483"
     variation       878
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34788593"
     variation       881
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:142129926"
     variation       883
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369182704"
     variation       889
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147794352"
     variation       936
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:146931383"
     variation       946
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372701237"
     variation       948
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201917577"
     variation       1036
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:375083855"
     variation       1061
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:35418490"
     variation       1136
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372600053"
     variation       1140
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:74089845"
     variation       1231
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:116201856"
     variation       1279
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:192439298"
     variation       1345
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:184352881"
     STS             1417..1653
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /standard_name="G64260"
                     /db_xref="UniSTS:166787"
     variation       1444
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:115278602"
     variation       1486..1487
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace=""
                     /replace="cccactactttagggggc"
                     /db_xref="dbSNP:139041759"
     variation       1501..1502
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace=""
                     /replace="gccccactactttagggg"
                     /db_xref="dbSNP:11267962"
     variation       1501
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201258829"
     variation       1502..1503
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace=""
                     /replace="gccccactactttagggg"
                     /db_xref="dbSNP:34095785"
     variation       1503..1507
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace=""
                     /replace="cccactactttagggggc"
                     /db_xref="dbSNP:71068192"
     variation       1507..1516
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace=""
                     /replace="cccactactttagggggc"
                     /db_xref="dbSNP:71912845"
     variation       1763..1764
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace=""
                     /replace="ttttt"
                     /db_xref="dbSNP:374010882"
     variation       1779..1780
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace=""
                     /replace="ttta"
                     /db_xref="dbSNP:75724555"
     variation       1815
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:190456317"
     variation       1903
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:3816152"
     variation       1957
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:140304286"
     variation       1960
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:3816153"
     variation       1969..1970
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /replace=""
                     /replace="tg"
                     /db_xref="dbSNP:71734226"
     polyA_signal    2029..2034
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
     polyA_site      2055
                     /gene="HOXC11"
                     /gene_synonym="HOX3H"
                     /experiment="experimental evidence, no additional details
                     recorded"
ORIGIN      

gtgctcagagagagagagactaagacggataacgcgtcatctcgccttcccaaattttcccccctcgctagaccgggtccaaaacctccatccggagccggcaggagaggagaacgatgtttaactcggtcaacctgggcaacttctgctctccgtcgcgcaaggagaggggcgcagatttcggcgagcgagggagctgcgcctccaacctctatctgcccagttgcacttactacatgcccgagttctccacggtctcctccttcctgccccaggccccctctcgtcagatctcctatccctactcggcccaagtgcccccggtccgggaggtctcctacggcctggagccatccggcaagtggcaccatcggaacagctactcctcctgctatgcggcggccgacgagcttatgcaccgggagtgcctgcctccttccaccgtcaccgagatcctcatgaaaaacgaaggctcctacggcggccaccaccaccccagcgccccgcacgcaacccccgccggcttctactcctcagtcaacaagaacagcgtcctgcctcaagccttcgaccgtttcttcgacaacgcctactgcggtggcggcgacccgcccgccgagcccccctgctccggcaagggcgaggccaagggggagcccgaggcacccccggcctcgggactggcgtcccgggctgaggcgggtgccgaggcggaggctgaggaggagaacacaaatcccagctcgtccggttcagcccactccgtggccaaggagccggccaaaggagccgcccccaacgccccccgcacccgcaagaagcgctgcccttattcgaaattccagatccgggaactggagcgagagtttttcttcaacgtgtatatcaacaaagagaagcggctgcagctgtcccggatgctgaacctgacggaccgacaagtgaaaatttggtttcagaacagaaggatgaaagaaaagaaactgagcagagaccggctgcagtatttctcgggaaatcctctgctgtaacctgcagaccgggcccttttgggggcggggggaggggaaaattattttattttatttttattttttattttctaactcgtcttctttccgccggtggaaaactggactgtggccagggctggcccccaccgctgtggccggcactccattccggaacctcctggaccctctatctgactctcgctgtgggacagggaccgggcctggaaagggggtgaagggaagtgtctgatgcacggcgagtgaacaccgttggcgccgaggccaagactttgatttaaaagaaaacacacctcggcgacaatgtcttgctgctcggattaggtgggggaggggcgacagtagtgagcgcctgagccgaacaatcctcgaactaaaagccttcccttgcccatgtgaaaagatccgctaagacagcatgtctgccagcggaaacttctcgagctcccccctctaccccgccccaccttgccccactactttagggggcagctaaatgtgatcctgccttgctgtgaaatttctgtaccttcaacctggtgttaggtgtgcaaagtccgtgtcctacctccgtcttcgccaaggccccgcccgagcctagttgttctccccctgaatgtgtagaaccttcctttgaaatttcttaatcggtgcattgaggtttccacatctttttccaagcagtgccccacttcatggatttatagctatagtctatgcagtcgttacctcttttttttttttttttaagaaaattgaagattggggtggtggaggcagtagggagatgggattgggcacctcccccgtgctggggcctggatttttgtaaataaatttcccaagcgtttctttccacctggagggaaagggggggacgcccccagtgagattcaaatcacgcatctctactcctctgcgtgagtgcgtgtgtacatgtgcactccccaccctgctcccttcccagagggattgctgtgaaatttttttggtggcaaataaagataaatttcattctgttcaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

//

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:3227 -> Molecular function: GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] evidence: IDA
            GeneID:3227 -> Molecular function: GO:0001077 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription] evidence: IDA
            GeneID:3227 -> Biological process: GO:0001656 [metanephros development] evidence: IEA
            GeneID:3227 -> Biological process: GO:0001759 [organ induction] evidence: IEA
            GeneID:3227 -> Biological process: GO:0007492 [endoderm development] evidence: TAS
            GeneID:3227 -> Biological process: GO:0009952 [anterior/posterior pattern specification] evidence: IEA
            GeneID:3227 -> Biological process: GO:0009954 [proximal/distal pattern formation] evidence: IEA
            GeneID:3227 -> Biological process: GO:0042733 [embryonic digit morphogenesis] evidence: IEA
            GeneID:3227 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IDA
            GeneID:3227 -> Biological process: GO:0060272 [embryonic skeletal joint morphogenesis] evidence: IEA
            GeneID:3227 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:3227 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
            GeneID:3227 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
            GeneID:3227 -> Cellular component: GO:0005739 [mitochondrion] evidence: IDA