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2020-10-24 05:54:19, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_014109               5580 bp    mRNA    linear   PRI 26-MAY-2013
DEFINITION  Homo sapiens ATPase family, AAA domain containing 2 (ATAD2), mRNA.
ACCESSION   NM_014109 NM_032365
VERSION     NM_014109.3  GI:167621406
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5580)
  AUTHORS   Fouret,R., Laffaire,J., Hofman,P., Beau-Faller,M., Mazieres,J.,
            Validire,P., Girard,P., Camilleri-Broet,S., Vaylet,F.,
            Leroy-Ladurie,F., Soria,J.C. and Fouret,P.
  TITLE     A comparative and integrative approach identifies ATPase family,
            AAA domain containing 2 as a likely driver of cell proliferation in
            lung adenocarcinoma
  JOURNAL   Clin. Cancer Res. 18 (20), 5606-5616 (2012)
   PUBMED   22914773
  REMARK    GeneRIF: However, only ATAD2, and not MYC, overexpression explained
            the behavior of proliferation-related genes and predicted a worse
            prognosis independently of disease stage in a large validation
            cohort
REFERENCE   2  (bases 1 to 5580)
  AUTHORS   Altintas,D.M., Shukla,M.S., Goutte-Gattat,D., Angelov,D.,
            Rouault,J.P., Dimitrov,S. and Samarut,J.
  TITLE     Direct cooperation between androgen receptor and E2F1 reveals a
            common regulation mechanism for androgen-responsive genes in
            prostate cells
  JOURNAL   Mol. Endocrinol. 26 (9), 1531-1541 (2012)
   PUBMED   22771493
  REMARK    GeneRIF: Data conclude that AR and E2F1 cooperation results from a
            chromatin looping over the ATAD2 promoter region between the ARBS
            and E2F1 binding site in an androgen-dependent manner
REFERENCE   3  (bases 1 to 5580)
  AUTHORS   Kalashnikova,E.V., Revenko,A.S., Gemo,A.T., Andrews,N.P.,
            Tepper,C.G., Zou,J.X., Cardiff,R.D., Borowsky,A.D. and Chen,H.W.
  TITLE     ANCCA/ATAD2 overexpression identifies breast cancer patients with
            poor prognosis, acting to drive proliferation and survival of
            triple-negative cells through control of B-Myb and EZH2
  JOURNAL   Cancer Res. 70 (22), 9402-9412 (2010)
   PUBMED   20864510
  REMARK    GeneRIF: Data show that that ANCCA is crucial for proliferation and
            survival of triple-negative/basal-like cancer cells and that it
            controls the expression of B-Myb and histone methyltransferase
            EZH2.
REFERENCE   4  (bases 1 to 5580)
  AUTHORS   Revenko,A.S., Kalashnikova,E.V., Gemo,A.T., Zou,J.X. and Chen,H.W.
  TITLE     Chromatin loading of E2F-MLL complex by cancer-associated
            coregulator ANCCA via reading a specific histone mark
  JOURNAL   Mol. Cell. Biol. 30 (22), 5260-5272 (2010)
   PUBMED   20855524
  REMARK    GeneRIF: Data report that ANCCA directly interacts with E2F1 to
            E2F3 in its complex with MLL and that its N terminus interacts with
            both the N and C termini of E2F1.
REFERENCE   5  (bases 1 to 5580)
  AUTHORS   Zou,J.X., Guo,L., Revenko,A.S., Tepper,C.G., Gemo,A.T., Kung,H.J.
            and Chen,H.W.
  TITLE     Androgen-induced coactivator ANCCA mediates specific androgen
            receptor signaling in prostate cancer
  JOURNAL   Cancer Res. 69 (8), 3339-3346 (2009)
   PUBMED   19318566
  REMARK    GeneRIF: Findings suggest that ANCCA plays an important role in
            prostate cancer by mediating specific AR functions in cancer cell
            survival and proliferation.
            GeneRIF: ANCCA interacts with AR, required for IGF1R,IRS-2,SGK1,
            survivin expression and proliferation and survival of prostate
            cancer cells. ANCCA itself is highly induced by androgen. Its
            overexpression is found in prostate cancers with high Gleason
            scores.
REFERENCE   6  (bases 1 to 5580)
  AUTHORS   Hsia,E.Y., Zou,J.X. and Chen,H.W.
  TITLE     The roles and action mechanisms of p160/SRC coactivators and the
            ANCCA coregulator in cancer
  JOURNAL   Prog Mol Biol Transl Sci 87, 261-298 (2009)
   PUBMED   20374707
  REMARK    GeneRIF: Genetic aberrations and dysregulation in expression of
            p160/SRC coactivators and the ANCCA in breast cancer, prostate
            cancer, and other nonhormone-responsive cancers, are reviewed.
            Review article
REFERENCE   7  (bases 1 to 5580)
  AUTHORS   Zou,J.X., Revenko,A.S., Li,L.B., Gemo,A.T. and Chen,H.W.
  TITLE     ANCCA, an estrogen-regulated AAA+ ATPase coactivator for ERalpha,
            is required for coregulator occupancy and chromatin modification
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 104 (46), 18067-18072 (2007)
   PUBMED   17998543
  REMARK    GeneRIF: ANCCA associates directly with ERalpha and ACTR. It is
            selectively recruited to a subset of ERalpha target genes (cyclin
            D1, c-myc, and E2F1) and is required for their estrogen-induced
            expression and breast cancer cell proliferation.
REFERENCE   8  (bases 1 to 5580)
  AUTHORS   Wang,A.G., Yoon,S.Y., Oh,J.H., Jeon,Y.J., Kim,M., Kim,J.M.,
            Byun,S.S., Yang,J.O., Kim,J.H., Kim,D.G., Yeom,Y.I., Yoo,H.S.,
            Kim,Y.S. and Kim,N.S.
  TITLE     Identification of intrahepatic cholangiocarcinoma related genes by
            comparison with normal liver tissues using expressed sequence tags
  JOURNAL   Biochem. Biophys. Res. Commun. 345 (3), 1022-1032 (2006)
   PUBMED   16712791
REFERENCE   9  (bases 1 to 5580)
  AUTHORS   Petroziello,J., Yamane,A., Westendorf,L., Thompson,M., McDonagh,C.,
            Cerveny,C., Law,C.L., Wahl,A. and Carter,P.
  TITLE     Suppression subtractive hybridization and expression profiling
            identifies a unique set of genes overexpressed in non-small-cell
            lung cancer
  JOURNAL   Oncogene 23 (46), 7734-7745 (2004)
   PUBMED   15334068
REFERENCE   10 (bases 1 to 5580)
  AUTHORS   Beausoleil,S.A., Jedrychowski,M., Schwartz,D., Elias,J.E.,
            Villen,J., Li,J., Cohn,M.A., Cantley,L.C. and Gygi,S.P.
  TITLE     Large-scale characterization of HeLa cell nuclear phosphoproteins
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004)
   PUBMED   15302935
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BP314109.1, BC113656.1,
            CB159561.1 and CA441499.1.
            On Feb 11, 2008 this sequence version replaced gi:24497617.
            
            Summary: A large family of ATPases has been described, whose key
            feature is that they share a conserved region of about 220 amino
            acids that contains an ATP-binding site. The proteins that belong
            to this family either contain one or two AAA (ATPases Associated
            with diverse cellular Activities) domains. AAA family proteins
            often perform chaperone-like functions that assist in the assembly,
            operation, or disassembly of protein complexes. The protein encoded
            by this gene contains two AAA domains, as well as a bromodomain.
            [provided by RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC112942.1, AL833653.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025098 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-86                BP314109.1         1-86
            87-4737             BC113656.1         1-4651
            4738-5122           CB159561.1         117-501
            5123-5580           CA441499.1         1-458               c
FEATURES             Location/Qualifiers
     source          1..5580
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q24.13"
     gene            1..5580
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /note="ATPase family, AAA domain containing 2"
                     /db_xref="GeneID:29028"
                     /db_xref="HGNC:30123"
                     /db_xref="HPRD:10678"
                     /db_xref="MIM:611941"
     exon            1..279
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    97..99
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /note="upstream in-frame stop codon"
     CDS             109..4281
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /EC_number="3.6.1.3"
                     /note="AAA nuclear coregulator cancer-associated protein"
                     /codon_start=1
                     /product="ATPase family AAA domain-containing protein 2"
                     /protein_id="NP_054828.2"
                     /db_xref="GI:24497618"
                     /db_xref="CCDS:CCDS6343.1"
                     /db_xref="GeneID:29028"
                     /db_xref="HGNC:30123"
                     /db_xref="HPRD:10678"
                     /db_xref="MIM:611941"
                     /translation="
MVVLRSSLELHNHSAASATGSLDLSSDFLSLEHIGRRRLRSAGAAQKKPAATTAKAGDGSSVKEVETYHRTRALRSLRKDAQNSSDSSFEKNVEITEQLANGRHFTRQLARQQADKKKEEHREDKVIPVTRSLRARNIVQSTEHLHEDNGDVEVRRSCRIRSRYSGVNQSMLFDKLITNTAEAVLQKMDDMKKMRRQRMRELEDLGVFNETEESNLNMYTRGKQKDIQRTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEENQKRYYLRQRKATVYYQAPLEKPRHQRKPNIFYSGPASPARPRYRLSSAGPRSPYCKRMNRRRHAIHSSDSTSSSSSEDEQHFERRRKRSRNRAINRCLPLNFRKDELKGIYKDRMKIGASLADVDPMQLDSSVRFDSVGGLSNHIAALKEMVVFPLLYPEVFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQAYQMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDSRGEIVVIGATNRLDSIDPALRRPGRFDREFLFSLPDKEARKEILKIHTRDWNPKPLDTFLEELAENCVGYCGADIKSICAEAALCALRRRYPQIYTTSEKLQLDLSSINISAKDFEVAMQKMIPASQRAVTSPGQALSTVVKPLLQNTVDKILEALQRVFPHAEFRTNKTLDSDISCPLLESDLAYSDDDVPSVYENGLSQKSSHKAKDNFNFLHLNRNACYQPMSFRPRILIVGEPGFGQGSHLAPAVIHALEKFTVYTLDIPVLFGVSTTSPEETCAQVIREAKRTAPSIVYVPHIHVWWEIVGPTLKATFTTLLQNIPSFAPVLLLATSDKPHSALPEEVQELFIRDYGEIFNVQLPDKEERTKFFEDLILKQAAKPPISKKKAVLQALEVLPVAPPPEPRSLTAEEVKRLEEQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESRKKRGCSSSKYAPSYYHVMPKQNSTLVGDKRSDPEQNEKLKTPSTPVACSTPAQLKRKIRKKSNWYLGTIKKRRKISQAKDDSQNAIDHKIESDTEETQDTSVDHNETGNTGESSVEENEKQQNASESKLELRNNSNTCNIENELEDSRKTTACTELRDKIACNGDASSSQIIHISDENEGKEMCVLRMTRARRSQVEQQQLITVEKALAILSQPTPSLVVDHERLKNLLKTVVKKSQNYNIFQLENLYAVISQCIYRHRKDHDKTSLIQKMEQEVENFSCSR
"
     misc_feature    616..618
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q6PL18.1); phosphorylation site"
     misc_feature    1072..1074
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1075..1077
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1087..1089
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q6PL18.1); phosphorylation site"
     misc_feature    1087..1089
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1117..1119
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q6PL18.1); phosphorylation site"
     misc_feature    1132..1134
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1456..1902
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes ABC; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    1483..1908
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /note="ATPases associated with a variety of cellular
                     activities; Region: AAA; smart00382"
                     /db_xref="CDD:197690"
     misc_feature    1507..1530
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    order(1510..1533,1699..1701,1831..1833)
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    1687..1704
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    1873..1875
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     misc_feature    2344..2346
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q6PL18.1); phosphorylation site"
     misc_feature    2359..2361
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q6PL18.1); phosphorylation site"
     misc_feature    2359..2361
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /citation=[10]
     misc_feature    3067..3399
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /note="Bromodomain; sub-family co-occurring with AAA
                     domains. Bromodomains are 110 amino acid long domains,
                     that are found in many chromatin associated proteins.
                     Bromodomains can interact specifically with acetylated
                     lysine. The structure(2DKW) in this...; Region: Bromo_AAA;
                     cd05528"
                     /db_xref="CDD:99957"
     misc_feature    order(3145..3147,3160..3162,3169..3171,3286..3288,
                     3298..3300,3328..3330)
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /note="putative acetyllysine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99957"
     misc_feature    3553..3555
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphothreonine; propagated from
                     UniProtKB/Swiss-Prot (Q6PL18.1); phosphorylation site"
     misc_feature    3562..3564
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphothreonine; propagated from
                     UniProtKB/Swiss-Prot (Q6PL18.1); phosphorylation site"
     misc_feature    3805..3807
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q6PL18.1); phosphorylation site"
     misc_feature    3835..3837
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    4012..4014
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q6PL18.1); phosphorylation site"
     exon            280..428
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            429..478
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            479..644
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            645..747
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            748..835
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            836..1039
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            1040..1157
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            1158..1265
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            1266..1374
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            1375..1490
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            1491..1665
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            1666..1754
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            1755..1914
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            1915..2005
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            2006..2320
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            2321..2453
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            2454..2640
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            2641..2826
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            2827..2962
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            2963..3159
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            3160..3319
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            3320..3442
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            3443..3586
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            3587..3976
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     variation       3947
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3758122"
     exon            3977..4110
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            4111..4239
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     exon            4240..5565
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /inference="alignment:Splign:1.39.8"
     STS             4335..4541
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /standard_name="RH80934"
                     /db_xref="UniSTS:84048"
     STS             4521..4708
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /standard_name="RH77936"
                     /db_xref="UniSTS:45896"
     variation       4755
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:9021"
     variation       4856..4857
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:4006505"
     variation       4922
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:4006507"
     variation       4952
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:4006508"
     variation       4954
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:4006509"
     STS             5275..5530
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /standard_name="WI-20906"
                     /db_xref="UniSTS:4329"
     STS             5328..5530
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /standard_name="RH80997"
                     /db_xref="UniSTS:84107"
     STS             5331..5412
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
                     /standard_name="D8S1689"
                     /db_xref="UniSTS:154250"
     polyA_signal    5535..5540
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
     polyA_site      5565
                     /gene="ATAD2"
                     /gene_synonym="ANCCA; PRO2000"
ORIGIN      
cgcggagcttgtggcgccagaattcggagcgcggaagagccagagctgcgagcgcctggagctggatctctctccggtcgcgcacgccgaggccagtagggagagaagatggtggttctccgcagcagcttggagctgcacaaccactccgcggcctcggccacgggctccttggacctgtccagtgacttcctcagtctggagcacatcggccggaggcggctccgctcggccggcgcggcgcagaagaaacccgcggcgaccacagccaaagcgggcgatgggtcatcagttaaggaagttgaaacctaccaccggacacgtgctttaagatctttgagaaaagatgcacagaattcttcagattctagttttgagaagaatgtggaaataacggagcaacttgctaatggcaggcattttacaaggcagttggccagacagcaggctgataaaaaaaaagaagagcacagagaagacaaagtgattccagttactcggtcattgagggctagaaacatcgttcaaagtacagaacacttacatgaagataatggtgatgttgaagtgcgtcgaagttgtaggattagaagtcgttatagtggtgtaaaccagtccatgctgtttgacaaacttataactaacactgctgaagctgtacttcaaaaaatggatgacatgaagaagatgcgtagacagcgaatgagagaacttgaagacttgggagtgtttaatgaaacagaagaaagcaatcttaatatgtacacaagaggaaaacagaaagatattcaaagaactgatgaagaaacaactgataatcaagaaggcagtgtggagtcatctgaagagggtgaagaccaagaacatgaagatgatggtgaagatgaagatgatgaagatgatgatgatgatgacgatgatgatgatgatgatgatgatgaagatgatgaagatgaagaagatggagaagaagagaatcagaagcgatattatcttagacagagaaaagctactgtttactatcaggctccattggaaaaacctcgtcaccagagaaagcccaacatattttatagtggcccagcttctcctgcaagaccaagataccgattatcttccgcaggaccaagaagtccttactgtaaacgaatgaacaggcgaaggcatgcaatccacagtagtgactcgacttcatcttcctcctctgaagatgaacagcactttgagaggcggaggaaaaggagtcgtaatagggctatcaataggtgcctcccactaaattttcggaaagatgaattaaaaggcatttataaagatcgaatgaaaattggagcaagccttgccgatgttgatccaatgcaactagattcttcagtacgatttgatagtgttggtggcctgtctaatcatatagcagctctaaaagagatggtggtgtttccattactttatccagaagtctttgaaaaatttaaaattcaacccccaagaggttgtttgttttatgggccacctggaactggaaagactctggttgccagagcacttgccaatgagtgcagtcaaggggataaaagagtagcatttttcatgaggaaaggtgctgattgtctaagtaaatgggtaggagaatctgaaagacagctacgattgctgtttgatcaggcctatcagatgcgcccatcaattattttttttgacgaaattgatggtctggctccagtacggtcaagcaggcaagatcagattcacagttctattgtttccaccctgctagctcttatggatggattggacagcagaggggaaattgtggtcattggtgctacgaacaggctagattctatagatcctgctttacgaaggcctggtcgctttgatagagaattcctctttagcctgcctgataaagaggctcgaaaagagattctaaagattcacaccagggattggaatcccaaaccactggacacatttttagaagagctagcagaaaactgtgttggatactgtggagcagatattaaatcaatatgtgctgaagctgctttatgtgctttacgacgacgctacccacagatctataccactagtgagaaactgcagttggatctctcttcaattaatatctcagctaaggatttcgaggtagctatgcaaaagatgataccagcctcccaaagagctgtgacatcacctgggcaggcactgtccaccgttgtgaaaccactcctgcaaaacactgttgacaagattttagaagccctgcagagagtatttccacatgcagaattcagaacaaataaaacattagactcagatatttcttgtcctctgctagaaagtgacttggcttacagtgatgatgatgttccatcagtttatgaaaatggactttctcagaaatcttctcataaggcaaaagacaattttaattttcttcatttgaatagaaatgcttgttaccaacctatgtcttttcgaccaagaatattgatagtaggagaaccaggatttgggcaaggttctcacttggcaccagctgtcattcatgctttggaaaagtttactgtatatacattagacattcctgttctttttggagttagtactacatcccctgaagaaacatgtgcccaggtgattcgtgaagctaagagaacagcaccaagtatagtgtatgttcctcatatccacgtgtggtgggaaatagttggaccgacacttaaagccacatttaccacattattacagaatattccttcatttgctccagttttactacttgcaacttctgacaaaccccattccgctttgccagaagaggtgcaagaattgtttatccgtgattatggagagatttttaatgtccagttaccggataaagaagaacggacaaaattttttgaagatttaattctaaaacaagctgctaagcctcctatatcaaaaaagaaagcagttttgcaggctttggaggtactcccagtagcaccaccacctgagccaagatcactgacagcagaagaagtgaaacgactagaagaacaagaagaagatacatttagagaactgaggattttcttaagaaatgttacacataggcttgctattgacaagcgattccgagtgtttactaagcctgttgaccctgatgaggttcctgattatgtcactgtaataaagcaaccaatggacctttcatctgtaatcagtaaaattgatctacacaagtatctgactgtgaaagactatttgagagatattgatctaatctgtagtaatgccttagaatacaatccagatagagatcctggagatcgtcttattaggcatagagcctgtgctttaagagatactgcctatgccataattaaagaagaacttgatgaagactttgagcagctctgtgaagaaattcaggaatctagaaagaaaagaggttgtagctcctccaaatatgccccgtcttactaccatgtgatgccaaagcaaaattccactcttgttggtgataaaagatcagacccagagcagaatgaaaagctaaagacaccgagtactcctgtggcttgcagcactcctgctcagttgaagaggaaaattcgcaaaaagtcaaactggtacttaggcaccataaaaaagcgaaggaagatttcacaggcaaaggatgatagccagaatgccatagatcacaaaattgagagtgatacagaggaaactcaagacacaagtgtagatcataatgagaccggaaacacaggagagtcttcggtggaagaaaatgaaaaacagcaaaatgcctctgaaagcaaactggaattgagaaataattcaaatacttgtaatatagagaatgagcttgaagactctaggaagactacagcatgtacagaattgagagacaagattgcttgtaatggagatgcttctagctctcagataatacatatttctgatgaaaatgaaggaaaagaaatgtgtgttctgcgaatgactcgagctagacgttcccaggtagaacagcagcagctcatcactgttgaaaaggctttggcaattctttctcagcctacaccctcacttgttgtggatcatgagcgattaaaaaatcttttgaagactgttgttaaaaaaagtcaaaactacaacatatttcagttggaaaatttgtatgcagtaatcagccaatgtatttatcggcatcgcaaggaccatgataaaacatcacttattcagaaaatggagcaagaggtagaaaacttcagttgttccagatgatgatgtcatggtatcgagtattctttatattcagttcctatttaagtcatttttgtcatgtccgcctaattgatgtagtatgaaaccctgcatctttaaggaaaagattaaaatagtaaaataaaagtatttaaactttcctgatatttatgtacatattaagataaatgtcatgtgtaagataactgataaatattggaactttgctagaacaagaccctgtagtaatagtaataatagttgaagtttggccaactcttaataaagttattttggtaactaatgttttatggcacttaagaataattagcagcgttaaattttgtttgtattaagcacttttaattttatccttcctaaaaatagtttattgtatctgacaagaaacttacttaaccattgtgtccttcccatcttttttgtcatctttgttttcttcaaatgccctcctcccatctgccttgagattccctcgtcttcacttaaaagccagagtgcaagtcatgatttgcgggagggctcttgaaccacttctggctgcaccacaattctgtacttgagtatcacagtcattgtttttgagacaaacatttttataattctaatttgggttaataaagattttaaatatttcttggtttacttttgtaattatatacacaacaaatgtattaataactaccttgttaaacaccttttaatagcacaaggtttttatatttgcaagctgttgatatctttctaaaactgtttaggttatagtctattgatactttttatatacaattttataaatataaatattataattttatattaatggtaccaaaaatacatttcttaaggttaaaagcatgcacttccatgcatacttgcttttggggagagtggggagaagacattctaataatcagtttgtgaaatagcttctgttggaaaccttttgaggggaataaggaatggtcatctaaaatgagagattctggattttaatgcagttcaaagttgagctgtatttttgttgttgatttatctggattttttttaaagccttctaaaacccagtgaattcaataccttaattagtacatactatcttatgtaatgcataaagcaatgccagtcactgagaacatttaaatatatttatattcctggagatacacattctcatttttgttggtttattataaattattcttctagatgcatcttttataactaggatttcattttgtgtgtatagcttatgtaataaattttaaaggtgaaaactctcttaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:29028 -> Molecular function: GO:0005524 [ATP binding] evidence: IEA
            GeneID:29028 -> Molecular function: GO:0016887 [ATPase activity] evidence: IEA
            GeneID:29028 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
            GeneID:29028 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: IEA
            GeneID:29028 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:29028 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
ANNOTATIONS from NCBI Entrez Gene (20130726):
            NP_054828 -> EC 3.6.1.3

by @meso_cacase at DBCLS
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