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2024-04-20 22:54:32, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_013233 3288 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens serine threonine kinase 39 (STK39), mRNA.
ACCESSION NM_013233
VERSION NM_013233.2 GI:115430251
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3288)
AUTHORS Ponce-Coria,J., Gagnon,K.B. and Delpire,E.
TITLE Calcium-binding protein 39 facilitates molecular interaction
between Ste20p proline alanine-rich kinase and oxidative stress
response 1 monomers
JOURNAL Am. J. Physiol., Cell Physiol. 303 (11), C1198-C1205 (2012)
PUBMED 23034389
REMARK GeneRIF: SPAK and OSR1, which are oftencoexpressed in cells can
form functional heterodimers.
REFERENCE 2 (bases 1 to 3288)
AUTHORS Vavolizza,R.D., Schmeidler,J., Ramoz,N., Buxbaum,J.D., Smith,C.J.
and Silverman,J.M.
TITLE The effect of an autism-associated polymorphism in the STK39 gene
on the autism symptom domains
JOURNAL J Autism Dev Disord 42 (2), 319-320 (2012)
PUBMED 21442361
REMARK GeneRIF: our results suggest no significant assocation between any
of the core autism symptom domains or the four additional
previously identified familial features and the rs1807984 SNP on
the STK39 gene.
REFERENCE 3 (bases 1 to 3288)
AUTHORS Yan,Y., Laroui,H., Ingersoll,S.A., Ayyadurai,S., Charania,M.,
Yang,S., Dalmasso,G., Obertone,T.S., Nguyen,H., Sitaraman,S.V. and
Merlin,D.
TITLE Overexpression of Ste20-related proline/alanine-rich kinase
exacerbates experimental colitis in mice
JOURNAL J. Immunol. 187 (3), 1496-1505 (2011)
PUBMED 21705622
REMARK GeneRIF: SPAK increases intestinal epithelial permeability; both
SPAK-transfected Caco2-cells and SPAK transgenic mice exhibit loss
of intestinal barrier function and homeostasis in inflammatory
bowel disease.
REFERENCE 4 (bases 1 to 3288)
AUTHORS Richardson,C., Sakamoto,K., de los Heros,P., Deak,M.,
Campbell,D.G., Prescott,A.R. and Alessi,D.R.
TITLE Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent
and -independent pathways
JOURNAL J. Cell. Sci. 124 (PT 5), 789-800 (2011)
PUBMED 21321328
REMARK GeneRIF: Data demonstrate that hypotonic low-chloride conditions
that activate the WNK1-SPAK and OSR1 pathway promote
phosphorylation of NKCC2 isoforms.
REFERENCE 5 (bases 1 to 3288)
AUTHORS Yang,D., Li,Q., So,I., Huang,C.L., Ando,H., Mizutani,A., Seki,G.,
Mikoshiba,K., Thomas,P.J. and Muallem,S.
TITLE IRBIT governs epithelial secretion in mice by antagonizing the
WNK/SPAK kinase pathway
JOURNAL J. Clin. Invest. 121 (3), 956-965 (2011)
PUBMED 21317537
REMARK GeneRIF: IRBIT opposes the effects of WNKs and SPAK by recruiting
PP1 to the complex to dephosphorylate CFTR and NBCe1-B, restoring
their cell surface expression, in addition to stimulating their
activities
REFERENCE 6 (bases 1 to 3288)
AUTHORS Moriguchi,T., Urushiyama,S., Hisamoto,N., Iemura,S., Uchida,S.,
Natsume,T., Matsumoto,K. and Shibuya,H.
TITLE WNK1 regulates phosphorylation of cation-chloride-coupled
cotransporters via the STE20-related kinases, SPAK and OSR1
JOURNAL J. Biol. Chem. 280 (52), 42685-42693 (2005)
PUBMED 16263722
REMARK GeneRIF: WNK1 and SPAK/OSR1 mediate the hypotonic stress signaling
pathway to cation-chloride-coupled cotransporters
REFERENCE 7 (bases 1 to 3288)
AUTHORS Piechotta,K., Garbarini,N., England,R. and Delpire,E.
TITLE Characterization of the interaction of the stress kinase SPAK with
the Na+-K+-2Cl- cotransporter in the nervous system: evidence for a
scaffolding role of the kinase
JOURNAL J. Biol. Chem. 278 (52), 52848-52856 (2003)
PUBMED 14563843
REFERENCE 8 (bases 1 to 3288)
AUTHORS Dowd,B.F. and Forbush,B.
TITLE PASK (proline-alanine-rich STE20-related kinase), a regulatory
kinase of the Na-K-Cl cotransporter (NKCC1)
JOURNAL J. Biol. Chem. 278 (30), 27347-27353 (2003)
PUBMED 12740379
REMARK GeneRIF: roles in phosphorylation and activation of the Na-K-Cl
cotransporter (NKCC1)
REFERENCE 9 (bases 1 to 3288)
AUTHORS Qi,H., Labrie,Y., Grenier,J., Fournier,A., Fillion,C. and Labrie,C.
TITLE Androgens induce expression of SPAK, a STE20/SPS1-related kinase,
in LNCaP human prostate cancer cells
JOURNAL Mol. Cell. Endocrinol. 182 (2), 181-192 (2001)
PUBMED 11514053
REFERENCE 10 (bases 1 to 3288)
AUTHORS Johnston,A.M., Naselli,G., Gonez,L.J., Martin,R.M., Harrison,L.C.
and DeAizpurua,H.J.
TITLE SPAK, a STE20/SPS1-related kinase that activates the p38 pathway
JOURNAL Oncogene 19 (37), 4290-4297 (2000)
PUBMED 10980603
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AF099989.1, AC016723.11 and
BF516344.1.
On Sep 30, 2006 this sequence version replaced gi:7019542.
Summary: This gene encodes a serine/threonine kinase that is
thought to function in the cellular stress response pathway. The
kinase is activated in response to hypotonic stress, leading to
phosphorylation of several cation-chloride-coupled cotransporters.
The catalytically active kinase specifically activates the p38 MAP
kinase pathway, and its interaction with p38 decreases upon
cellular stress, suggesting that this kinase may serve as an
intermediate in the response to cellular stress. [provided by
RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AF099989.1, AF030403.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
ERS025081, ERS025082 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-51 AF099989.1 2-52
52-309 AF099989.1 65-322
310-2228 AF099989.1 329-2247
2229-3119 AC016723.11 170127-171017 c
3120-3288 BF516344.1 1-169 c
FEATURES Location/Qualifiers
source 1..3288
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2q24.3"
gene 1..3288
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/note="serine threonine kinase 39"
/db_xref="GeneID:27347"
/db_xref="HGNC:17717"
/db_xref="MIM:607648"
exon 1..368
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="alignment:Splign:1.39.8"
STS 133..1825
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/db_xref="UniSTS:482333"
CDS 161..1798
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/EC_number="2.7.11.1"
/note="serine threonine kinase 39 (STE20/SPS1 homolog,
yeast); Ste20-like protein kinase; small intestine
SPAK-like kinase; proline-alanine-rich STE20-related
kinase; ste-20-related kinase; serine/threonine-protein
kinase 39"
/codon_start=1
/product="STE20/SPS1-related proline-alanine-rich protein
kinase"
/protein_id="NP_037365.2"
/db_xref="GI:115430252"
/db_xref="CCDS:CCDS42770.1"
/db_xref="GeneID:27347"
/db_xref="HGNC:17717"
/db_xref="MIM:607648"
/translation="
MAEPSGSPVHVQLPQQAAPVTAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICRDAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSASTIPEQIQSLSVHDSQGPPNANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQLSVS
"
misc_feature 341..1171
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/note="Catalytic domain of the Protein Serine/Threonine
Kinases, Oxidative stress response kinase and
Ste20-related proline alanine-rich kinase; Region:
STKc_OSR1_SPAK; cd06610"
/db_xref="CDD:173726"
misc_feature 347..1171
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/note="Serine/Threonine protein kinases, catalytic domain;
Region: S_TKc; smart00220"
/db_xref="CDD:197582"
misc_feature order(365..379,389..391,428..430,434..436,524..526,
572..583,590..595,602..604,734..736,740..751,755..757,
788..790,797..799,854..865,869..871,953..955,980..982)
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/note="active site"
/db_xref="CDD:173726"
misc_feature order(365..379,389..391,428..430,434..436,524..526,
572..583,590..595,602..604,740..742,746..751,755..757,
788..790)
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:173726"
misc_feature order(374..379,734..736,740..748,797..799,854..865,
869..871,953..955,980..982)
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:173726"
misc_feature order(785..826,845..871)
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/note="activation loop (A-loop); other site"
/db_xref="CDD:173726"
misc_feature 1085..1087
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by PKC/PRKCQ; propagated from
UniProtKB/Swiss-Prot (Q9UEW8.3); phosphorylation site"
misc_feature 1085..1087
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/citation=[10]
/db_xref="HPRD:02710"
misc_feature 1127..1129
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/citation=[10]
/db_xref="HPRD:02710"
misc_feature 1205..1207
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-acetyllysine; propagated from
UniProtKB/Swiss-Prot (Q9UEW8.3); acetylation site"
misc_feature 1238..1258
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9UEW8.3);
Region: Nuclear localization signal (Potential)"
misc_feature 1268..1270
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UEW8.3); phosphorylation site"
misc_feature 1268..1270
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1271..1273
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UEW8.3); phosphorylation site"
misc_feature 1313..1315
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UEW8.3); phosphorylation site"
misc_feature 1313..1315
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1319..1333
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9UEW8.3);
Region: Caspase cleavage related site"
misc_feature 1514..1609
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/note="Oxidative-stress-responsive kinase 1 C terminal;
Region: OSR1_C; pfam12202"
/db_xref="CDD:204847"
exon 369..481
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="alignment:Splign:1.39.8"
exon 482..590
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="alignment:Splign:1.39.8"
exon 591..732
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="alignment:Splign:1.39.8"
exon 733..788
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="alignment:Splign:1.39.8"
exon 789..898
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="alignment:Splign:1.39.8"
exon 899..1000
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="alignment:Splign:1.39.8"
exon 1001..1134
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="alignment:Splign:1.39.8"
exon 1135..1183
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="alignment:Splign:1.39.8"
exon 1184..1249
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="alignment:Splign:1.39.8"
variation 1220
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/replace="a"
/replace="c"
/db_xref="dbSNP:1802105"
exon 1250..1372
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="alignment:Splign:1.39.8"
exon 1373..1402
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="alignment:Splign:1.39.8"
exon 1403..1465
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="alignment:Splign:1.39.8"
exon 1466..1536
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="alignment:Splign:1.39.8"
exon 1537..1589
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="alignment:Splign:1.39.8"
exon 1590..1658
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="alignment:Splign:1.39.8"
exon 1659..1723
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="alignment:Splign:1.39.8"
exon 1724..3274
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/inference="alignment:Splign:1.39.8"
STS 1797..1952
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/standard_name="RH68427"
/db_xref="UniSTS:31029"
polyA_site 1979
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
variation 2452
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/replace="a"
/replace="g"
/db_xref="dbSNP:1061471"
variation 2682
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/replace="g"
/replace="t"
/db_xref="dbSNP:3769428"
STS 2855..3023
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/standard_name="RH99072"
/db_xref="UniSTS:85155"
variation 3065
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
/replace="a"
/replace="g"
/db_xref="dbSNP:3769429"
polyA_signal 3250..3255
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
polyA_site 3274
/gene="STK39"
/gene_synonym="DCHT; PASK; SPAK"
ORIGIN
gctccctcccctcctagctggcttcggcggggacggcggcggcggcggcgggcggggagggcgtgcgccggccgagaggtgtcggcggcgaggcaaaggaagtttcaagtggaaggtcgtccgtcggccggcgcgtcctcctgctctcctccgcagcatcatggcggagccgagcggctcgcccgtgcacgtccagcttccccagcaggcggccccggtgacagcggcggcggcggcggccccggcggccgcgacagcagcgccggccccggcagctcccgcggccccggccccggccccggccccggcggcacaggctgtcggctggcccatctgcagggacgcgtacgagctgcaggaggttatcggcagtggagctactgctgtggttcaggcagccctatgcaaacccaggcaagaacgtgtagcaataaaacggatcaacttggaaaaatgccagaccagtatggatgaactattaaaagaaattcaagccatgagtcagtgcagccatcccaacgtagtgacctattacacctcttttgtggtcaaagatgaactttggctggtcatgaaattactaagtggaggttcaatgttggatatcataaaatacattgtcaaccgaggagaacacaagaatggagttctggaagaggcaataatagcaacaattcttaaagaggttttggaaggcttagactatctacacagaaacggtcagattcacagggatttgaaagctggtaatattcttctgggtgaggatggttcagtacaaatagcagattttggggtaagtgcgttcctagcaacagggggtgatgttacccgaaataaagtaagaaaaacattcgttggcaccccatgttggatggctcctgaagtcatggaacaggtgagaggctatgacttcaaggctgacatgtggagttttggaataactgccattgaattagcaacaggagcagcgccttatcacaaatatcctcccatgaaagtgttaatgttgactttgcaaaatgatccacccactttggaaacaggggtagaggataaagaaatgatgaaaaagtacggcaagtcctttagaaaattactttcactgtgtcttcagaaagatccttccaaaaggcccacagcagcagaacttttaaaatgcaaattcttccagaaagccaagaacagagagtacctgattgagaagctgcttacaagaacaccagacatagcccaaagagccaaaaaggtaagaagagttcctgggtcaagtggtcaccttcataaaaccgaagacggggactgggagtggagtgacgacgagatggatgagaagagcgaagaagggaaagcagctttttctcaggaaaagtcacgaagagtaaaagaagaaaatccagagattgcagtgagtgccagcaccatccccgaacaaatacagtccctctctgtgcacgactctcagggcccacccaatgctaatgaagactacagagaagcttcttcttgtgccgtgaacctcgttttgagattaagaaactccagaaaggaacttaatgacatacgatttgagtttactccaggaagagatacagcagatggtgtatctcaggagctcttctctgctggcttggtggatggtcacgatgtagttatagtggctgctaatttacagaagattgtagatgatcccaaagctttaaaaacattgacatttaagttggcttctggctgtgatgggtcggagattcctgatgaagtgaagctgattgggtttgctcagttgagtgtcagctgatgtatgtcccttgatgtcaccctgatctgtcatgccccaccgccacccctactcccttcaaccctccctctttctgcccatttcctcccaccccctcactcccatttcctagcaaaatcagaagattgtgaagaggccggcttcaacaaaatgggataaaaaaataattttttaaaacttacaacactccgagttctgctttattctctagcaatccacagtacaagaacaagcaaatgccacagctgcacgactgttgctcatttttccaaaagctatttaatattcttagcaatcaatttggatatcccttaagtgaaaagaatctgaaatacactcaggtggtcttatttattggcaacaaaaggaattttctatccagaagcctatttctcctttcattgttgttatttctgttataatactttaattgtacatctgacaatactgcctcttttatgttgtatttagaaattaatatacttataaaattaagatttattagccaaacttgaattctagttttaaaactgactgtgaattttatttttcatatatttatgcattacacaccttagctataagaaaaaaagggttttgattatatgcttcttgcagttaatctcgttatttaaacaaaaagttttgggtctgtctttggagtatttgtaacttctaaattttgaaatgactgaattaggaatttggatgcttattcttttagtctgtttgcctaaaaaccaatttacaatctgactgtctcttgggagagggaggtgccttgcaaactttcacattaagaatgtgcctgaggctgctttactctggaatagtctcagatctaaaatttcctctatataaggtggcatatgttaagttttgcttcattggaccgtttagaatgctatgtaaaatgttgccattctgttagattgctaactatatacccatctctgatttggctctccttaagtgataggatttgttattctaaaggtgataaacttgaaaatatcagaatctgagttttacttgaaattttgcagaatacccaggtggagtgaaaattggaagggttttgtgcaatgactaaaaggtaaaacgctgttaaggttcaagaatcaatactttcaacccaagtagccctctgcttgactgtatattatggaactagtaaaccttaggattttgaaaattggagtctaatctttcaaggaggtgggctcccaggatggtaccattgctctttcctagctaaccctagatatggcagctctttaatgtacttcaaaaagcaaatatatattactaaggaaaaaaagttatttataattgccttgtcataattgttaaggtgttctagagccatttgcatacaatttaatgtaatttcattccattctattgtttacacaacgattactcgaagatgactgcaaaggtaaaaggaaaataaaagtgtattgcacaatgagaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:27347 -> Molecular function: GO:0004702 [receptor signaling protein serine/threonine kinase activity] evidence: NAS
GeneID:27347 -> Molecular function: GO:0005524 [ATP binding] evidence: NAS
GeneID:27347 -> Molecular function: GO:0019901 [protein kinase binding] evidence: IEA
GeneID:27347 -> Biological process: GO:0006468 [protein phosphorylation] evidence: NAS
GeneID:27347 -> Biological process: GO:0006950 [response to stress] evidence: NAS
GeneID:27347 -> Biological process: GO:0023014 [signal transduction by phosphorylation] evidence: NAS
GeneID:27347 -> Biological process: GO:0043268 [positive regulation of potassium ion transport] evidence: IEA
GeneID:27347 -> Biological process: GO:0050727 [regulation of inflammatory response] evidence: IEA
GeneID:27347 -> Cellular component: GO:0005634 [nucleus] evidence: NAS
GeneID:27347 -> Cellular component: GO:0005737 [cytoplasm] evidence: NAS
GeneID:27347 -> Cellular component: GO:0005856 [cytoskeleton] evidence: IEA
GeneID:27347 -> Cellular component: GO:0016323 [basolateral plasma membrane] evidence: IEA
GeneID:27347 -> Cellular component: GO:0016324 [apical plasma membrane] evidence: IEA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_037365 -> EC 2.7.11.1
by
@meso_cacase at
DBCLS
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