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2024-04-27 06:59:38, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_012234 4678 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens RING1 and YY1 binding protein (RYBP), mRNA.
ACCESSION NM_012234
VERSION NM_012234.5 GI:299116874
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4678)
AUTHORS Zhang,Y., Endam,L.M., Filali-Mouhim,A., Zhao,L., Desrosiers,M.,
Han,D. and Zhang,L.
TITLE Polymorphisms in RYBP and AOAH genes are associated with chronic
rhinosinusitis in a Chinese population: a replication study
JOURNAL PLoS ONE 7 (6), E39247 (2012)
PUBMED 22723975
REMARK GeneRIF: Polymorphisms in RYBP and AOAH genes are associated with
chronic rhinosinusitis in a Chinese population.
REFERENCE 2 (bases 1 to 4678)
AUTHORS Lango Allen,H., Estrada,K., Lettre,G., Berndt,S.I., Weedon,M.N.,
Rivadeneira,F., Willer,C.J., Jackson,A.U., Vedantam,S.,
Raychaudhuri,S., Ferreira,T., Wood,A.R., Weyant,R.J., Segre,A.V.,
Speliotes,E.K., Wheeler,E., Soranzo,N., Park,J.H., Yang,J.,
Gudbjartsson,D., Heard-Costa,N.L., Randall,J.C., Qi,L., Vernon
Smith,A., Magi,R., Pastinen,T., Liang,L., Heid,I.M., Luan,J.,
Thorleifsson,G., Winkler,T.W., Goddard,M.E., Sin Lo,K., Palmer,C.,
Workalemahu,T., Aulchenko,Y.S., Johansson,A., Zillikens,M.C.,
Feitosa,M.F., Esko,T., Johnson,T., Ketkar,S., Kraft,P., Mangino,M.,
Prokopenko,I., Absher,D., Albrecht,E., Ernst,F., Glazer,N.L.,
Hayward,C., Hottenga,J.J., Jacobs,K.B., Knowles,J.W., Kutalik,Z.,
Monda,K.L., Polasek,O., Preuss,M., Rayner,N.W., Robertson,N.R.,
Steinthorsdottir,V., Tyrer,J.P., Voight,B.F., Wiklund,F., Xu,J.,
Zhao,J.H., Nyholt,D.R., Pellikka,N., Perola,M., Perry,J.R.,
Surakka,I., Tammesoo,M.L., Altmaier,E.L., Amin,N., Aspelund,T.,
Bhangale,T., Boucher,G., Chasman,D.I., Chen,C., Coin,L.,
Cooper,M.N., Dixon,A.L., Gibson,Q., Grundberg,E., Hao,K., Juhani
Junttila,M., Kaplan,L.M., Kettunen,J., Konig,I.R., Kwan,T.,
Lawrence,R.W., Levinson,D.F., Lorentzon,M., McKnight,B.,
Morris,A.P., Muller,M., Suh Ngwa,J., Purcell,S., Rafelt,S.,
Salem,R.M., Salvi,E., Sanna,S., Shi,J., Sovio,U., Thompson,J.R.,
Turchin,M.C., Vandenput,L., Verlaan,D.J., Vitart,V., White,C.C.,
Ziegler,A., Almgren,P., Balmforth,A.J., Campbell,H., Citterio,L.,
De Grandi,A., Dominiczak,A., Duan,J., Elliott,P., Elosua,R.,
Eriksson,J.G., Freimer,N.B., Geus,E.J., Glorioso,N., Haiqing,S.,
Hartikainen,A.L., Havulinna,A.S., Hicks,A.A., Hui,J., Igl,W.,
Illig,T., Jula,A., Kajantie,E., Kilpelainen,T.O., Koiranen,M.,
Kolcic,I., Koskinen,S., Kovacs,P., Laitinen,J., Liu,J., Lokki,M.L.,
Marusic,A., Maschio,A., Meitinger,T., Mulas,A., Pare,G.,
Parker,A.N., Peden,J.F., Petersmann,A., Pichler,I.,
Pietilainen,K.H., Pouta,A., Ridderstrale,M., Rotter,J.I.,
Sambrook,J.G., Sanders,A.R., Schmidt,C.O., Sinisalo,J., Smit,J.H.,
Stringham,H.M., Bragi Walters,G., Widen,E., Wild,S.H.,
Willemsen,G., Zagato,L., Zgaga,L., Zitting,P., Alavere,H.,
Farrall,M., McArdle,W.L., Nelis,M., Peters,M.J., Ripatti,S., van
Meurs,J.B., Aben,K.K., Ardlie,K.G., Beckmann,J.S., Beilby,J.P.,
Bergman,R.N., Bergmann,S., Collins,F.S., Cusi,D., den Heijer,M.,
Eiriksdottir,G., Gejman,P.V., Hall,A.S., Hamsten,A., Huikuri,H.V.,
Iribarren,C., Kahonen,M., Kaprio,J., Kathiresan,S., Kiemeney,L.,
Kocher,T., Launer,L.J., Lehtimaki,T., Melander,O., Mosley,T.H. Jr.,
Musk,A.W., Nieminen,M.S., O'Donnell,C.J., Ohlsson,C., Oostra,B.,
Palmer,L.J., Raitakari,O., Ridker,P.M., Rioux,J.D., Rissanen,A.,
Rivolta,C., Schunkert,H., Shuldiner,A.R., Siscovick,D.S.,
Stumvoll,M., Tonjes,A., Tuomilehto,J., van Ommen,G.J., Viikari,J.,
Heath,A.C., Martin,N.G., Montgomery,G.W., Province,M.A., Kayser,M.,
Arnold,A.M., Atwood,L.D., Boerwinkle,E., Chanock,S.J., Deloukas,P.,
Gieger,C., Gronberg,H., Hall,P., Hattersley,A.T., Hengstenberg,C.,
Hoffman,W., Lathrop,G.M., Salomaa,V., Schreiber,S., Uda,M.,
Waterworth,D., Wright,A.F., Assimes,T.L., Barroso,I., Hofman,A.,
Mohlke,K.L., Boomsma,D.I., Caulfield,M.J., Cupples,L.A.,
Erdmann,J., Fox,C.S., Gudnason,V., Gyllensten,U., Harris,T.B.,
Hayes,R.B., Jarvelin,M.R., Mooser,V., Munroe,P.B., Ouwehand,W.H.,
Penninx,B.W., Pramstaller,P.P., Quertermous,T., Rudan,I.,
Samani,N.J., Spector,T.D., Volzke,H., Watkins,H., Wilson,J.F.,
Groop,L.C., Haritunians,T., Hu,F.B., Kaplan,R.C., Metspalu,A.,
North,K.E., Schlessinger,D., Wareham,N.J., Hunter,D.J.,
O'Connell,J.R., Strachan,D.P., Wichmann,H.E., Borecki,I.B., van
Duijn,C.M., Schadt,E.E., Thorsteinsdottir,U., Peltonen,L.,
Uitterlinden,A.G., Visscher,P.M., Chatterjee,N., Loos,R.J.,
Boehnke,M., McCarthy,M.I., Ingelsson,E., Lindgren,C.M.,
Abecasis,G.R., Stefansson,K., Frayling,T.M. and Hirschhorn,J.N.
TITLE Hundreds of variants clustered in genomic loci and biological
pathways affect human height
JOURNAL Nature 467 (7317), 832-838 (2010)
PUBMED 20881960
REFERENCE 3 (bases 1 to 4678)
AUTHORS Chen,D., Zhang,J., Li,M., Rayburn,E.R., Wang,H. and Zhang,R.
TITLE RYBP stabilizes p53 by modulating MDM2
JOURNAL EMBO Rep. 10 (2), 166-172 (2009)
PUBMED 19098711
REMARK GeneRIF: RYBP interacts with MDM2 via residues 1-73 and 144-228 &
decreases MDM2-mediated p53 ubiquitination, stabilizing p53
increasing its activity. RYBP is decreased in human cancer tissues.
REFERENCE 4 (bases 1 to 4678)
AUTHORS Novak,R.L. and Phillips,A.C.
TITLE Adenoviral-mediated Rybp expression promotes tumor cell-specific
apoptosis
JOURNAL Cancer Gene Ther. 15 (11), 713-722 (2008)
PUBMED 18551146
REMARK GeneRIF: Adenovirus expressing Rybp synergistically cooperates with
the death receptor ligand, tumor necrosis factor-alpha, in the
induction of apoptosis, and thus may have clinical applicability
for the treatment of cancer.
REFERENCE 5 (bases 1 to 4678)
AUTHORS Gearhart,M.D., Corcoran,C.M., Wamstad,J.A. and Bardwell,V.J.
TITLE Polycomb group and SCF ubiquitin ligases are found in a novel BCOR
complex that is recruited to BCL6 targets
JOURNAL Mol. Cell. Biol. 26 (18), 6880-6889 (2006)
PUBMED 16943429
REFERENCE 6 (bases 1 to 4678)
AUTHORS Schlisio,S., Halperin,T., Vidal,M. and Nevins,J.R.
TITLE Interaction of YY1 with E2Fs, mediated by RYBP, provides a
mechanism for specificity of E2F function
JOURNAL EMBO J. 21 (21), 5775-5786 (2002)
PUBMED 12411495
REMARK GeneRIF: interacts specifically with the E2F2 and E2F3 family
members, dependent on the marked box domain in these proteins
REFERENCE 7 (bases 1 to 4678)
AUTHORS Sawa,C., Yoshikawa,T., Matsuda-Suzuki,F., Delehouzee,S., Goto,M.,
Watanabe,H., Sawada,J., Kataoka,K. and Handa,H.
TITLE YEAF1/RYBP and YAF-2 are functionally distinct members of a
cofactor family for the YY1 and E4TF1/hGABP transcription factors
JOURNAL J. Biol. Chem. 277 (25), 22484-22490 (2002)
PUBMED 11953439
REMARK GeneRIF: YEAF1/RYBP and YAF-2 are functionally distinct members of
a cofactor family for the YY1 and E4TF1/hGABP transcription
factors.
REFERENCE 8 (bases 1 to 4678)
AUTHORS Zheng,L., Schickling,O., Peter,M.E. and Lenardo,M.J.
TITLE The death effector domain-associated factor plays distinct
regulatory roles in the nucleus and cytoplasm
JOURNAL J. Biol. Chem. 276 (34), 31945-31952 (2001)
PUBMED 11395500
REFERENCE 9 (bases 1 to 4678)
AUTHORS Trimarchi,J.M., Fairchild,B., Wen,J. and Lees,J.A.
TITLE The E2F6 transcription factor is a component of the mammalian
Bmi1-containing polycomb complex
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 98 (4), 1519-1524 (2001)
PUBMED 11171983
REFERENCE 10 (bases 1 to 4678)
AUTHORS Garcia,E., Marcos-Gutierrez,C., del Mar Lorente,M., Moreno,J.C. and
Vidal,M.
TITLE RYBP, a new repressor protein that interacts with components of the
mammalian Polycomb complex, and with the transcription factor YY1
JOURNAL EMBO J. 18 (12), 3404-3418 (1999)
PUBMED 10369680
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
BC036459.1, AB029551.1, AC104330.2 and BF939411.1.
On Jun 23, 2010 this sequence version replaced gi:112363091.
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
CDS exon combination :: AB029551.1, BG827273.1 [ECO:0000331]
RNAseq introns :: mixed/partial sample support ERS025081,
ERS025082 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-240 BC036459.1 6-245
241-761 AB029551.1 250-770
762-4649 AC104330.2 123166-127053
4650-4678 BF939411.1 1-29 c
FEATURES Location/Qualifiers
source 1..4678
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3p13"
gene 1..4678
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/note="RING1 and YY1 binding protein"
/db_xref="GeneID:23429"
/db_xref="HGNC:10480"
/db_xref="MIM:607535"
CDS 184..870
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/note="YY1 and E4TF1 associated factor 1; death effector
domain-associated factor; ring1 interactor RYBP;
apoptin-associating protein 1; APAP-1; DED-associated
factor; YY1 and E4TF1-associated factor 1"
/codon_start=1
/product="RING1 and YY1-binding protein"
/protein_id="NP_036366.3"
/db_xref="GI:112363092"
/db_xref="GeneID:23429"
/db_xref="HGNC:10480"
/db_xref="MIM:607535"
/translation="
MTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPEKDKEISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF
"
misc_feature 250..318
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/note="Zinc finger domain; Region: ZnF_RBZ; smart00547"
/db_xref="CDD:197784"
misc_feature 478..480
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q8N488.2); phosphorylation site"
misc_feature 562..564
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q8N488.2); phosphorylation site"
misc_feature 571..573
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q8N488.2); phosphorylation site"
misc_feature 610..861
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q8N488.2);
Region: Interaction with E4TF1B"
misc_feature 862..864
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q8N488.2); phosphorylation site"
variation 372
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/replace="a"
/replace="g"
/db_xref="dbSNP:11542657"
variation 1140
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/replace="a"
/replace="t"
/db_xref="dbSNP:200918240"
STS 1194..1290
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/standard_name="STS-AA027856"
/db_xref="UniSTS:60066"
STS 1672..1821
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/standard_name="SGC34284"
/db_xref="UniSTS:59418"
STS 2056..2280
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/standard_name="SHGC-77078"
/db_xref="UniSTS:81182"
STS 2205..2306
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/standard_name="WI-11804"
/db_xref="UniSTS:70615"
variation 2584
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/replace="a"
/replace="g"
/db_xref="dbSNP:3203732"
STS 3594..3820
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/standard_name="SHGC-52585"
/db_xref="UniSTS:65128"
variation 3935
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/replace="c"
/replace="t"
/db_xref="dbSNP:12956"
STS 4361..4636
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/standard_name="HSC10B052"
/db_xref="UniSTS:81514"
STS 4402..4570
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/standard_name="A001W26"
/db_xref="UniSTS:60275"
STS 4402..4570
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/standard_name="G19717"
/db_xref="UniSTS:60274"
STS 4404..4503
/gene="RYBP"
/gene_synonym="AAP1; DEDAF; YEAF1"
/standard_name="Cda10b05"
/db_xref="UniSTS:49666"
ORIGIN
agtctcgtccggagactggcagcggcggcggcggcggcggccggagctcgagccccagcggctgagggcgggcgggcgggcgcgggggagggaggggggccggtccgcgacgactccccggacggcgtttctcctccgagcggcgccggtttcggcttggggggggcggggtacagcccatccatgaccatgggcgacaagaagagcccgaccaggccaaaaagacaagcgaaacctgccgcagacgaagggttttgggattgtagcgtctgcaccttcagaaacagtgctgaagcctttaaatgcagcatctgcgatgtgaggaaaggcacctccaccagaaaacctcggatcaattctcagctggtggcacaacaagtggcacaacagtatgccaccccaccaccccctaaaaaggagaagaaggagaaagttgaaaagcaggacaaagagaaacctgagaaagacaaggaaattagtcctagtgttaccaagaaaaataccaacaagaaaaccaaaccaaagtctgacattctgaaagatcctcctagtgaagcaaacagcatacagtctgcaaatgctacaacaaagaccagcgaaacaaatcacacctcaaggccccggctgaaaaacgtggacaggagcactgcacagcagttggcagtaactgtgggcaacgtcaccgtcattatcacagactttaaggaaaagactcgctcctcatcgacatcctcatccacagtgacctccagtgcagggtcagaacagcagaaccagagcagctcggggtcagagagcacagacaagggctcctcccgttcctccacgccaaagggcgacatgtcagcagtcaatgatgaatctttctgaaattgcacatggaattgtgaaaactatgaatcagggtatgaaattcaaaacctccacctgcccatgctgcttgcatccctggagaatcttctgtggacatcgacctcttagtgatgctgccaggataatttctgcttgccatgggcatctggccaccaaggaatttcgcaccctgacgattactcttgacacttttatgtattccattgttttatatgattttcctaacaatcatttataattggatgtgctcctgaatctactttttataaaaaaaaaaaaatctgctgtgcacaattttccatgtacattacaactggttttttgtttttgttttgttgccggtggggagggctgggagggggagggaacttttatttattgtgttcacaaactccatcctttcagcatatccttttaagtttagttctttcttccagttatactatgtactatcagttttgatataactatatatatataaatataaaattatatataaagggttatttgaaaccaatccatggcaacgctggtgcttgatacactgtgaagtgaatacaacattgaacagttacagatctgggacagtcccttctatgaaagtgctgaaatttaattaaaatcagtcttatatgaagtatgttccaatccatgtgggaacttgactctctcatctgtctaaagagtactggacgatataaaaatatatattttttaaacaatgtgatctcaaatttaaagactgctccagatagcctgcatttgcaatggaataactgacaaatcacaagtggtttagttgggcagggctttgatcattcaaaagtaactaaagtagctccagaatgccaagtattcgtgtaaattacggttacatgttatcatttgctgttcttacataagcactcatgaaaatatggtattctgtaacttgaattccatccattttccagacctctactcatgtctgaggtaaatctagaaattgtcttagttttaggattgaaacagtctataaactgtatttttggtccatccaggaagctagtcccttgtttctcctttctacatgacattgcagtggtggtttctgtaattaaaatttgtttgcctcatgtccctttgtctgataaaccttcactctaccgattcagttgtgagcattctttttttccttctcaaaacctactatgatttgttttactgaacaaaggttatcaaccacacatccagtcctgacatggagcttttcagtgtttggagacatttctcaatcccctgctgtggtaggaactccagtggtgaacggcttgcgcgcctgcagccagagttgcagggaaagctcgtacttactgcgagcagcatgtaatcttttttcttcctggacataaagatagcttgagtaaactgttctatttcattctcttcactctttttactgtcttgcaaaaaaaaaaaaaaaaaaaataatcaaagaccactaataagattccacctctccttattaaaataattttttaaaattttgttttgcttttgtttggatgtggggtctctcttctatttgacttttacatttagatacagagtttgtagtacttcagagacatttcaagcatgagaatttgaggttacctctctttatttgacctttagggactcacgggagggcagcctgatttgtaatgaagcaccacattttggtgttaaaaacctggtttgcttaataatagcagtaatttctgtctgtggaggcaacaaataaaaaaattaacagcttgaattgagtagccaacaggaaaggttcctttcacatttacattaaaactattctgtagtcactaatgtaccataatttaaattcttttctcaaaggtatagattataaagcagtgccatttgttgctgtggtcctattctcaaatgcatggacaatgttcccccctttttaaaataatgcttgtgtctgggatgcaagctttgcttatctttttaaatacatttttaaagtatttattaatgaaccaaaggaaatcagatgctttctataagcatcagaatatataatacatagtgatttgactatgaattttaaatccacattttaatattggtgggatattgcaaagacattccttctaaagttttaatattccttttattaagggtctcagggagggtaaattagtcagccatatttattttccagaggtttaagaaattgctgtttttaactttttgaaaaaacttaaatgccaccaaactcatgtaggttgcactgcttattgaaccaataactgttggtatgcactttgttcagacacactgtgtactttttcaaaaactagtttcatgtaaagtgattggaccccatagattagtggaaaaagctgattaaccagctactcataggctgctaattcattcatgccaatgttttggtttttcagttttgcctccgtgataaattaaagaatggggaggggtgaaggaaggggaagaagattgctttagaacaagtggcatgaaattaccatctttgtagaaaccgcagctaacagtgggagttatctaagcaatcagatgttacagggccagccctttagctgctgtggtgtattctgttgggtagtgaggtagtaggtactttatagacttttaattttggaaattgatgacatccctcaggcatgtattctggaaatggaattcctgtaacttcctgtgtctgcagtatgccctacaattagtaggcagcgtgtaaaaacactagtgtagattataaagatatacattaaaagaggaccagaaatacttggtattcagtggcacagaaagcaggttaaacaaacaaaaagcacagtgttacgcttgcaagtttccatttgttttaataccacgcaatctttcacactcgtgcgtgtgcgcgcacacagagcttacctgacttgctctgcttgagtcatgcagttacaaaaaaaaagacatcttgacacccacacaatattctaatcaaaacctttcagtttcaatctggatatttaaaaacattggcagaagcttctgtgagtttagttccactaagatgtttcacctgccttatcaagaccattctcagtctacttttttaagctaccgtatcttaaattattgaaaatttattaattgctgaatatataataacctttgcttgtatgtaaccgaaaatggtttaagagccaacatttagagtatgacaatggagctgaacagtttttaatgcgcaagcagttctgttcttgtgtatgacttgtaaccttaatttactgtgtaaagatggttacattatttccttagctttgtttgttggagacaaatagagaatgcttgttaagtatgtcaaaacaatcttatcttgtgaatttttgttaatgtattatacgagctatatttttcatttgcccagaaagacagcttgtataacgcttttggaagtttctgctctgtaatgtctttagagctgacagtctgttaggtttgtttttttcttcatgctaaagtgtcagttggtggttttgtgaactggtcaaaaattcacaggtcttaaatgttttgggggaaatttatattggacactgctctttgtctagcaaataaaagatgttaatatattcctgttactggcatgtgcacgactatgttattagaagccactttatcattttcctgctttaaatagaaatgtctatttatgaattctgcttgtagttttttcacaaataaaatagtaaaatttacattggaaatcttaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:23429 -> Molecular function: GO:0003677 [DNA binding] evidence: IEA
GeneID:23429 -> Molecular function: GO:0003714 [transcription corepressor activity] evidence: IEA
GeneID:23429 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:23429 -> Molecular function: GO:0008270 [zinc ion binding] evidence: IEA
GeneID:23429 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IEA
GeneID:23429 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
GeneID:23429 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:23429 -> Biological process: GO:0007275 [multicellular organismal development] evidence: TAS
GeneID:23429 -> Biological process: GO:0035518 [histone H2A monoubiquitination] evidence: IDA
GeneID:23429 -> Cellular component: GO:0005654 [nucleoplasm] evidence: IEA
GeneID:23429 -> Cellular component: GO:0005737 [cytoplasm] evidence: IEA
GeneID:23429 -> Cellular component: GO:0031519 [PcG protein complex] evidence: IDA
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