GGRNA Home | Help | Advanced search

2019-03-23 03:30:15, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_012154               3520 bp    mRNA    linear   PRI 07-JUL-2013
DEFINITION  Homo sapiens argonaute RISC catalytic component 2 (AGO2),
            transcript variant 1, mRNA.
ACCESSION   NM_012154
VERSION     NM_012154.3  GI:257467480
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3520)
  AUTHORS   Shen,J., Xia,W., Khotskaya,Y.B., Huo,L., Nakanishi,K., Lim,S.O.,
            Du,Y., Wang,Y., Chang,W.C., Chen,C.H., Hsu,J.L., Wu,Y., Lam,Y.C.,
            James,B.P., Liu,X., Liu,C.G., Patel,D.J. and Hung,M.C.
  TITLE     EGFR modulates microRNA maturation in response to hypoxia through
            phosphorylation of AGO2
  JOURNAL   Nature 497 (7449), 383-387 (2013)
   PUBMED   23636329
  REMARK    GeneRIF: EGFR, which is the product of a well-characterized
            oncogene in human cancers, suppresses the maturation of specific
            tumour-suppressor-like miRNAs in response to hypoxic stress through
            phosphorylation of argonaute 2 (AGO2) at Tyr 393
REFERENCE   2  (bases 1 to 3520)
  AUTHORS   Cheng,N., Li,Y. and Han,Z.G.
  TITLE     Argonaute2 promotes tumor metastasis by way of up-regulating focal
            adhesion kinase expression in hepatocellular carcinoma
  JOURNAL   Hepatology 57 (5), 1906-1918 (2013)
   PUBMED   23258480
  REMARK    GeneRIF: Argonaute2 promotes tumor metastasis by way of
            up-regulating focal adhesion kinase expression in hepatocellular
            carcinoma.
REFERENCE   3  (bases 1 to 3520)
  AUTHORS   Zhang,X., Graves,P. and Zeng,Y.
  TITLE     Overexpression of human Argonaute2 inhibits cell and tumor growth
  JOURNAL   Biochim. Biophys. Acta 1830 (3), 2553-2561 (2013)
   PUBMED   23201202
  REMARK    GeneRIF: Overexpression of human Argonaute2 inhibits cell and tumor
            growth.
REFERENCE   4  (bases 1 to 3520)
  AUTHORS   Del-Aguila,J.L., Beitelshees,A.L., Cooper-Dehoff,R.M.,
            Chapman,A.B., Gums,J.G., Bailey,K., Gong,Y., Turner,S.T.,
            Johnson,J.A. and Boerwinkle,E.
  TITLE     Genome-wide association analyses suggest NELL1 influences adverse
            metabolic response to HCTZ in African Americans
  JOURNAL   Pharmacogenomics J. (2013) In press
   PUBMED   23400010
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   5  (bases 1 to 3520)
  AUTHORS   Thibault,P.A., Huys,A., Dhillon,P. and Wilson,J.A.
  TITLE     MicroRNA-122-dependent and -independent replication of Hepatitis C
            Virus in Hep3B human hepatoma cells
  JOURNAL   Virology 436 (1), 179-190 (2013)
   PUBMED   23245472
  REMARK    GeneRIF: findings show that Argonaute-2 (Ago2) is required for
            miR-122-dependent replication of Hepatitis C Virus, but dispensable
            for miR-122-independent replication, confirming Ago2's role in
            mediating the activity of miR-122
REFERENCE   6  (bases 1 to 3520)
  AUTHORS   Doi,N., Zenno,S., Ueda,R., Ohki-Hamazaki,H., Ui-Tei,K. and Saigo,K.
  TITLE     Short-interfering-RNA-mediated gene silencing in mammalian cells
            requires Dicer and eIF2C translation initiation factors
  JOURNAL   Curr. Biol. 13 (1), 41-46 (2003)
   PUBMED   12526743
REFERENCE   7  (bases 1 to 3520)
  AUTHORS   Carmell,M.A., Xuan,Z., Zhang,M.Q. and Hannon,G.J.
  TITLE     The Argonaute family: tentacles that reach into RNAi, developmental
            control, stem cell maintenance, and tumorigenesis
  JOURNAL   Genes Dev. 16 (21), 2733-2742 (2002)
   PUBMED   12414724
  REMARK    Review article
REFERENCE   8  (bases 1 to 3520)
  AUTHORS   Martinez,J., Patkaniowska,A., Urlaub,H., Luhrmann,R. and Tuschl,T.
  TITLE     Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
  JOURNAL   Cell 110 (5), 563-574 (2002)
   PUBMED   12230974
REFERENCE   9  (bases 1 to 3520)
  AUTHORS   Mourelatos,Z., Dostie,J., Paushkin,S., Sharma,A., Charroux,B.,
            Abel,L., Rappsilber,J., Mann,M. and Dreyfuss,G.
  TITLE     miRNPs: a novel class of ribonucleoproteins containing numerous
            microRNAs
  JOURNAL   Genes Dev. 16 (6), 720-728 (2002)
   PUBMED   11914277
REFERENCE   10 (bases 1 to 3520)
  AUTHORS   Koesters,R., Adams,V., Betts,D., Moos,R., Schmid,M., Siermann,A.,
            Hassam,S., Weitz,S., Lichter,P., Heitz,P.U., von Knebel
            Doeberitz,M. and Briner,J.
  TITLE     Human eukaryotic initiation factor EIF2C1 gene: cDNA sequence,
            genomic organization, localization to chromosomal bands 1p34-p35,
            and expression
  JOURNAL   Genomics 61 (2), 210-218 (1999)
   PUBMED   10534406
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AI468419.1, BC125214.1,
            BC125213.1 and BC018727.1.
            On Sep 9, 2009 this sequence version replaced gi:29171733.
            
            Summary: This gene encodes a member of the Argonaute family of
            proteins which play a role in RNA interference. The encoded protein
            is highly basic, and contains a PAZ domain and a PIWI domain. It
            may interact with dicer1 and play a role in
            short-interfering-RNA-mediated gene silencing. Multiple transcript
            variants encoding different isoforms have been found for this gene.
            [provided by RefSeq, Sep 2009].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns ERS025088,
                              ERS025099 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1                 AI468419.1         1-1
            2-881               BC125214.1         1-880
            882-2875            BC125213.1         688-2681
            2876-3244           BC125214.1         2772-3140
            3245-3520           BC018727.1         2492-2767
FEATURES             Location/Qualifiers
     source          1..3520
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q24"
     gene            1..3520
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /note="argonaute RISC catalytic component 2"
                     /db_xref="GeneID:27161"
                     /db_xref="HGNC:3263"
                     /db_xref="HPRD:06943"
                     /db_xref="MIM:606229"
     exon            1..63
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     CDS             42..2621
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /note="isoform 1 is encoded by transcript variant 1;
                     argonaute 2; protein argonaute-2; PPD; hAgo2; eIF2C 2;
                     eIF-2C 2; argonaute2; protein slicer; PAZ Piwi domain
                     protein; eukaryotic translation initiation factor 2C, 2"
                     /codon_start=1
                     /product="protein argonaute-2 isoform 1"
                     /protein_id="NP_036286.2"
                     /db_xref="GI:29171734"
                     /db_xref="CCDS:CCDS6380.1"
                     /db_xref="GeneID:27161"
                     /db_xref="HGNC:3263"
                     /db_xref="HPRD:06943"
                     /db_xref="MIM:606229"
                     /translation="
MYSGAGPALAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA
"
     misc_feature    114..2615
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /note="protein argonaute; Provisional; Region: PLN03202"
                     /db_xref="CDD:178743"
     misc_feature    564..722
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /note="Domain of unknown function (DUF1785); Region:
                     DUF1785; pfam08699"
                     /db_xref="CDD:204029"
     misc_feature    720..1082
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:30331"
     misc_feature    order(876..878,921..923,963..965,975..977,1029..1031,
                     1050..1052,1056..1058)
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:30331"
     misc_feature    1215..2492
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /note="Piwi_ago-like: PIWI domain, Argonaute-like
                     subfamily. Argonaute is the central component of the
                     RNA-induced silencing complex (RISC) and related
                     complexes. The PIWI domain is the C-terminal portion of
                     Argonaute and consists of two subdomains, one of...;
                     Region: Piwi_ago-like; cd04657"
                     /db_xref="CDD:72942"
     misc_feature    order(1626..1628,1638..1640,1674..1685,1692..1694,
                     1716..1718,1725..1727,1737..1739,1749..1751)
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /note="5' RNA guide strand anchoring site; other site"
                     /db_xref="CDD:72942"
     misc_feature    order(1830..1832,1836..1838,2046..2048,2460..2462)
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /note="active site"
                     /db_xref="CDD:72942"
     misc_feature    2139..2141
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="4-hydroxyproline; propagated from
                     UniProtKB/Swiss-Prot (Q9UKV8.3); hydroxylation site"
     exon            64..256
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     exon            257..377
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     exon            378..559
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     exon            560..696
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     exon            697..831
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     exon            832..919
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     variation       881
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2292778"
     exon            920..1067
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     exon            1068..1187
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     variation       1142
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2271738"
     exon            1188..1310
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     exon            1311..1444
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     exon            1445..1629
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     variation       1484
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2292781"
     exon            1630..1789
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     exon            1790..1880
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     exon            1881..2075
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     STS             1989..2588
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /standard_name="Eif2c2"
                     /db_xref="UniSTS:479157"
     exon            2076..2210
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     variation       2082
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1137903"
     exon            2211..2312
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     exon            2313..2512
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     exon            2513..3500
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /inference="alignment:Splign:1.39.8"
     STS             2686..2890
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /standard_name="RH45183"
                     /db_xref="UniSTS:89345"
     polyA_signal    2867..2872
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
     variation       2876
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1060832"
     variation       2883
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2944776"
     polyA_site      2896
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
     STS             3209..3310
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
                     /standard_name="WI-11623"
                     /db_xref="UniSTS:81391"
     polyA_site      3500
                     /gene="AGO2"
                     /gene_synonym="EIF2C2; Q10"
ORIGIN      
gcggccgcccctcggccccggagcccctcggcggcgccaccatgtactcgggagccggccccgcacttgcacctcctgcgccgccgccccccatccaaggatatgccttcaagcctccacctagacccgactttgggacctccgggagaacaatcaaattacaggccaatttcttcgaaatggacatccccaaaattgacatctatcattatgaattggatatcaagccagagaagtgcccgaggagagttaacagggaaatcgtggaacacatggtccagcactttaaaacacagatctttggggatcggaagcccgtgtttgacggcaggaagaatctatacacagccatgccccttccgattgggagggacaaggtggagctggaggtcacgctgccaggagaaggcaaggatcgcatcttcaaggtgtccatcaagtgggtgtcctgcgtgagcttgcaggcgttacacgatgcactttcagggcggctgcccagcgtcccttttgagacgatccaggccctggacgtggtcatgaggcacttgccatccatgaggtacacccccgtgggccgctccttcttcaccgcgtccgaaggctgctctaaccctcttggcgggggccgagaagtgtggtttggcttccatcagtccgtccggccttctctctggaaaatgatgctgaatattgatgtgtcagcaacagcgttttacaaggcacagccagtaatcgagtttgtttgtgaagttttggattttaaaagtattgaagaacaacaaaaacctctgacagattcccaaagggtaaagtttaccaaagaaattaaaggtctaaaggtggagataacgcactgtgggcagatgaagaggaagtaccgcgtctgcaatgtgacccggcggcccgccagtcaccaaacattcccgctgcagcaggagagcgggcagacggtggagtgcacggtggcccagtatttcaaggacaggcacaagttggttctgcgctacccccacctcccatgtttacaagtcggacaggagcagaaacacacctaccttcccctggaggtctgtaacattgtggcaggacaaagatgtattaaaaaattaacggacaatcagacctcaaccatgatcagagcgactgctaggtcggcgcccgatcggcaagaagagattagcaaattgatgcgaagtgcaagtttcaacacagatccatacgtccgtgaatttggaatcatggtcaaagatgagatgacagacgtgactgggcgggtgctgcagccgccctccatcctctacgggggcaggaataaagctattgcgacccctgtccagggcgtctgggacatgcggaacaagcagttccacacgggcatcgagatcaaggtgtgggccattgcgtgcttcgccccccagcgccagtgcacggaagtccatctgaagtccttcacagagcagctcagaaagatctcgagagacgccggcatgcccatccagggccagccgtgcttctgcaaatacgcgcagggggcggacagcgtggagcccatgttccggcacctgaagaacacgtatgcgggcctgcagctggtggtggtcatcctgcccggcaagacgcccgtgtacgccgaggtcaagcgcgtgggagacacggtgctggggatggccacgcagtgcgtgcagatgaagaacgtgcagaggaccacgccacagaccctgtccaacctctgcctgaagatcaacgtcaagctgggaggcgtgaacaacatcctgctgccccagggcaggccgccggtgttccagcagcccgtcatctttctgggagcagacgtcactcacccccccgccggggatgggaagaagccctccattgccgccgtggtgggcagcatggacgcccaccccaatcgctactgcgccaccgtgcgcgtgcagcagcaccggcaggagatcatacaagacctggccgccatggtccgcgagctcctcatccagttctacaagtccacgcgcttcaagcccacccgcatcatcttctaccgcgacggtgtctctgaaggccagttccagcaggttctccaccacgagttgctggccatccgtgaggcctgtatcaagctagaaaaagactaccagcccgggatcaccttcatcgtggtgcagaagaggcaccacacccggctcttctgcactgacaagaacgagcgggttgggaaaagtggaaacattccagcaggcacgactgtggacacgaaaatcacccaccccaccgagttcgacttctacctgtgtagtcacgctggcatccaggggacaagcaggccttcgcactatcacgtcctctgggacgacaatcgtttctcctctgatgagctgcagatcctaacctaccagctgtgtcacacctacgtgcgctgcacacgctccgtgtccatcccagcgccagcatactacgctcacctggtggccttccgggccaggtaccacctggtggataaggaacatgacagtgctgaaggaagccatacctctgggcagagtaacgggcgagaccaccaagcactggccaaggcggtccaggttcaccaagacactctgcgcaccatgtactttgcttgacatgttttagtgtttagcgattgtgtaccgagtgggattcacgagaccagctacactcagaccaacagatggccagcccttccgtgacagccagcatcgaacatgagacgtcattgattttattagattctccgttttccagaatgccttccgtcccagatttcaaacttggattttgaactgcagacctgtatgagaacccaatgtcataggaaatatggtttgctaaaatctataagctgcttattaaaacagagtcccgtgtgtcctaaaaatctcctaaaaccagtctatgaactcagggctttaaaacatttttaatttatttggtcattcaatttacttgtttttaatacatgattctctatgaaattgatgggctcaaactagctgtgaatcttctgagagtgaaagcaacacaaaacacaagtgtggttttaaagccttgaacattctgatgttgtcactaaagttgatttccaggcgatgctcgtgtgcccctggcgtggctcacccaagttcctcgactgagggccggtggccatgcagaggcgtccgcaggtgccgtgttctgccagcaccgcccttcacccggcctgaactaaggagcagtggcagaaggtgggccccgtgtgtttacagcatttccaggtccagagaggttggcagacaagtgccattttaataaaaaatgtatttaaaaaaagaaaaaagacaatatactgacagtctaatcatcagatttgtcctataggactgtgacatttattttccaaagtttttaaagaatacgggtctgtggtgataaatacagtacaatcctttttcactgttatgtctttaatgtaagagaagaatatatatatctggtttgcagtaaaaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:27161 -> Molecular function: GO:0000340 [RNA 7-methylguanosine cap binding] evidence: IDA
            GeneID:27161 -> Molecular function: GO:0003729 [mRNA binding] evidence: IEA
            GeneID:27161 -> Molecular function: GO:0003743 [translation initiation factor activity] evidence: NAS
            GeneID:27161 -> Molecular function: GO:0004521 [endoribonuclease activity] evidence: EXP
            GeneID:27161 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:27161 -> Molecular function: GO:0035197 [siRNA binding] evidence: IDA
            GeneID:27161 -> Molecular function: GO:0046872 [metal ion binding] evidence: IEA
            GeneID:27161 -> Molecular function: GO:0070551 [endoribonuclease activity, cleaving siRNA-paired mRNA] evidence: IDA
            GeneID:27161 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
            GeneID:27161 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: IEA
            GeneID:27161 -> Biological process: GO:0006412 [translation] evidence: NAS
            GeneID:27161 -> Biological process: GO:0006413 [translational initiation] evidence: NAS
            GeneID:27161 -> Biological process: GO:0007173 [epidermal growth factor receptor signaling pathway] evidence: TAS
            GeneID:27161 -> Biological process: GO:0007219 [Notch signaling pathway] evidence: TAS
            GeneID:27161 -> Biological process: GO:0008543 [fibroblast growth factor receptor signaling pathway] evidence: TAS
            GeneID:27161 -> Biological process: GO:0009791 [post-embryonic development] evidence: IEA
            GeneID:27161 -> Biological process: GO:0010467 [gene expression] evidence: TAS
            GeneID:27161 -> Biological process: GO:0031047 [gene silencing by RNA] evidence: ISS
            GeneID:27161 -> Biological process: GO:0031054 [pre-miRNA processing] evidence: IDA
            GeneID:27161 -> Biological process: GO:0035278 [negative regulation of translation involved in gene silencing by miRNA] evidence: IDA
            GeneID:27161 -> Biological process: GO:0035278 [negative regulation of translation involved in gene silencing by miRNA] evidence: IMP
            GeneID:27161 -> Biological process: GO:0035279 [mRNA cleavage involved in gene silencing by miRNA] evidence: IDA
            GeneID:27161 -> Biological process: GO:0035279 [mRNA cleavage involved in gene silencing by miRNA] evidence: IMP
            GeneID:27161 -> Biological process: GO:0038095 [Fc-epsilon receptor signaling pathway] evidence: TAS
            GeneID:27161 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
            GeneID:27161 -> Biological process: GO:0045947 [negative regulation of translational initiation] evidence: IDA
            GeneID:27161 -> Biological process: GO:0048011 [neurotrophin TRK receptor signaling pathway] evidence: TAS
            GeneID:27161 -> Biological process: GO:0048015 [phosphatidylinositol-mediated signaling] evidence: TAS
            GeneID:27161 -> Biological process: GO:0060213 [positive regulation of nuclear-transcribed mRNA poly(A) tail shortening] evidence: ISS
            GeneID:27161 -> Biological process: GO:1900153 [positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay] evidence: ISS
            GeneID:27161 -> Cellular component: GO:0000932 [cytoplasmic mRNA processing body] evidence: IDA
            GeneID:27161 -> Cellular component: GO:0005634 [nucleus] evidence: IEA
            GeneID:27161 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
            GeneID:27161 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:27161 -> Cellular component: GO:0005844 [polysome] evidence: IDA
            GeneID:27161 -> Cellular component: GO:0005845 [mRNA cap binding complex] evidence: IDA
            GeneID:27161 -> Cellular component: GO:0016442 [RNA-induced silencing complex] evidence: IDA
            GeneID:27161 -> Cellular component: GO:0030529 [ribonucleoprotein complex] evidence: IDA
            GeneID:27161 -> Cellular component: GO:0035068 [micro-ribonucleoprotein complex] evidence: IDA

by @meso_cacase at DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.