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2024-03-29 15:18:33, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_007222               5139 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens zinc fingers and homeoboxes 1 (ZHX1), transcript
            variant 2, mRNA.
ACCESSION   NM_007222
VERSION     NM_007222.4  GI:323510646
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5139)
  AUTHORS   Bird,L.E., Ren,J., Nettleship,J.E., Folkers,G.E., Owens,R.J. and
            Stammers,D.K.
  TITLE     Novel structural features in two ZHX homeodomains derived from a
            systematic study of single and multiple domains
  JOURNAL   BMC Struct. Biol. 10, 13 (2010)
   PUBMED   20509910
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5139)
  AUTHORS   Wienk,H., Lammers,I., Hotze,A., Wu,J., Wechselberger,R.W.,
            Owens,R., Stammers,D.K., Stuart,D., Kaptein,R. and Folkers,G.E.
  TITLE     The tandem zinc-finger region of human ZHX adopts a novel C2H2 zinc
            finger structure with a C-terminal extension
  JOURNAL   Biochemistry 48 (21), 4431-4439 (2009)
   PUBMED   19348505
  REMARK    GeneRIF: structure of the tandem zinc-finger region of human ZHX1
REFERENCE   3  (bases 1 to 5139)
  AUTHORS   Kim,S.H., Park,J., Choi,M.C., Kim,H.P., Park,J.H., Jung,Y.,
            Lee,J.H., Oh,D.Y., Im,S.A., Bang,Y.J. and Kim,T.Y.
  TITLE     Zinc-fingers and homeoboxes 1 (ZHX1) binds DNA methyltransferase
            (DNMT) 3B to enhance DNMT3B-mediated transcriptional repression
  JOURNAL   Biochem. Biophys. Res. Commun. 355 (2), 318-323 (2007)
   PUBMED   17303076
  REMARK    GeneRIF: ZHX1 enhanced the transcriptional repression mediated by
            DNMT3B when DNMT3B is directly targeted to DNA. These results
            showed for the first the direct linkage between DNMT and
            zinc-fingers homeoboxes protein, leading to enhanced gene silencing
            by DNMT3B
REFERENCE   4  (bases 1 to 5139)
  AUTHORS   Ogata-Kawata,H., Yamada,K., Uesaka-Yoshino,M., Kagawa,N. and
            Miyamoto,K.
  TITLE     BS69, a corepressor interacting with ZHX1, is a bifunctional
            transcription factor
  JOURNAL   Front. Biosci. 12, 1911-1926 (2007)
   PUBMED   17127430
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5139)
  AUTHORS   Liu,G., Clement,L.C., Kanwar,Y.S., Avila-Casado,C. and Chugh,S.S.
  TITLE     ZHX proteins regulate podocyte gene expression during the
            development of nephrotic syndrome
  JOURNAL   J. Biol. Chem. 281 (51), 39681-39692 (2006)
   PUBMED   17056598
  REMARK    GeneRIF: ZHX proteins 1, 2 and 3 are major transcriptional
            mediators of podocyte disease
            Erratum:[J Biol Chem. 2007 Apr 27;282(17):13140]
REFERENCE   6  (bases 1 to 5139)
  AUTHORS   Yamada,K., Kawata,H., Shou,Z., Hirano,S., Mizutani,T., Yazawa,T.,
            Sekiguchi,T., Yoshino,M., Kajitani,T. and Miyamoto,K.
  TITLE     Analysis of zinc-fingers and homeoboxes (ZHX)-1-interacting
            proteins: molecular cloning and characterization of a member of the
            ZHX family, ZHX3
  JOURNAL   Biochem. J. 373 (PT 1), 167-178 (2003)
   PUBMED   12659632
  REMARK    GeneRIF: a search of ZHX1-interacting proteins using a yeast
            two-hybrid system
REFERENCE   7  (bases 1 to 5139)
  AUTHORS   Yamada,K., Kawata,H., Matsuura,K., Shou,Z., Hirano,S., Mizutani,T.,
            Yazawa,T., Yoshino,M., Sekiguchi,T., Kajitani,T. and Miyamoto,K.
  TITLE     Functional analysis and the molecular dissection of zinc-fingers
            and homeoboxes 1 (ZHX1)
  JOURNAL   Biochem. Biophys. Res. Commun. 297 (2), 368-374 (2002)
   PUBMED   12237128
  REMARK    GeneRIF: This study characterized features of ZHX-1 involved in
            nuclear localization, dimerization, and transcriptional activity,
            and mapped these domains.
REFERENCE   8  (bases 1 to 5139)
  AUTHORS   Hirano,S., Yamada,K., Kawata,H., Shou,Z., Mizutani,T., Yazawa,T.,
            Kajitani,T., Sekiguchi,T., Yoshino,M., Shigematsu,Y., Mayumi,M. and
            Miyamoto,K.
  TITLE     Rat zinc-fingers and homeoboxes 1 (ZHX1), a nuclear
            factor-YA-interacting nuclear protein, forms a homodimer
  JOURNAL   Gene 290 (1-2), 107-114 (2002)
   PUBMED   12062805
REFERENCE   9  (bases 1 to 5139)
  AUTHORS   Yamada,K., Osawa,H. and Granner,D.K.
  TITLE     Identification of proteins that interact with NF-YA
  JOURNAL   FEBS Lett. 460 (1), 41-45 (1999)
   PUBMED   10571058
REFERENCE   10 (bases 1 to 5139)
  AUTHORS   Yamada,K., Printz,R.L., Osawa,H. and Granner,D.K.
  TITLE     Human ZHX1: cloning, chromosomal location, and interaction with
            transcription factor NF-Y
  JOURNAL   Biochem. Biophys. Res. Commun. 261 (3), 614-621 (1999)
   PUBMED   10441475
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DA238313.1, AF195766.1,
            CA776642.1, BC040481.1 and AK025236.1.
            On Feb 17, 2011 this sequence version replaced gi:63079679.
            
            Summary: The members of the zinc fingers and homeoboxes gene family
            are nuclear homodimeric transcriptional repressors that interact
            with the A subunit of nuclear factor-Y (NF-YA) and contain two
            C2H2-type zinc fingers and five homeobox DNA-binding domains. This
            gene encodes member 1 of this gene family. In addition to forming
            homodimers, this protein heterodimerizes with members 2 and 3 of
            the zinc fingers and homeoboxes family. Alternative splicing
            results in multiple transcript variants. Read-through transcription
            also exists between this gene and the downstream chromosome 8 open
            reading frame 76 (C8orf76) gene. [provided by RefSeq, Feb 2011].
            
            Transcript Variant: This variant (2) uses an alternate splice site
            in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode
            the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC040481.1, AF195766.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025082 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-237               DA238313.1         1-237
            238-3713            AF195766.1         1-3476
            3714-4172           CA776642.1         136-594
            4173-5093           BC040481.1         3994-4914
            5094-5139           AK025236.1         2584-2629
FEATURES             Location/Qualifiers
     source          1..5139
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q24.13"
     gene            1..5139
                     /gene="ZHX1"
                     /note="zinc fingers and homeoboxes 1"
                     /db_xref="GeneID:11244"
                     /db_xref="HGNC:12871"
                     /db_xref="MIM:604764"
     exon            1..271
                     /gene="ZHX1"
                     /inference="alignment:Splign:1.39.8"
     exon            272..385
                     /gene="ZHX1"
                     /inference="alignment:Splign:1.39.8"
     exon            386..3235
                     /gene="ZHX1"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    587..589
                     /gene="ZHX1"
                     /note="upstream in-frame stop codon"
     variation       601
                     /gene="ZHX1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:16898197"
     CDS             611..3232
                     /gene="ZHX1"
                     /note="zinc fingers and homeobox 1; zinc finger and
                     homeodomain protein 1"
                     /codon_start=1
                     /product="zinc fingers and homeoboxes protein 1"
                     /protein_id="NP_009153.3"
                     /db_xref="GI:63079680"
                     /db_xref="CCDS:CCDS6342.1"
                     /db_xref="GeneID:11244"
                     /db_xref="HGNC:12871"
                     /db_xref="MIM:604764"
                     /translation="
MASRRKSTTPCMVLASEQDPDLELISDLDEGPPVLTPVENTRAESISSDEEVHESVDSDNQQNKKVEGGYECKYCTFQTPDLNMFTFHVDSEHPNVVLNSSYVCVECNFLTKRYDALSEHNLKYHPGEENFKLTMVKRNNQTIFEQTINDLTFDGSFVKEENAEQAESTEVSSSGISISKTPIMKMMKNKVENKRIAVHHNSVEDVPEEKENEIKPDREEIVENPSSSASESNTSTSIVNRIHPSTASTVVTPAAVLPGLAQVITAVSAQQNSNLIPKVLIPVNSIPTYNAALDNNPLLLNTYNKFPYPTMSEITVLSAQAKYTEEQIKIWFSAQRLKHGVSWTPEEVEEARRKQFNGTVHTVPQTITVIPTHISTGSNGLPSILQTCQIVGQPGLVLTQVAGTNTLPVTAPIALTVAGVPSQNNIQKSQVPAAQPTAETKPATAAVPTSQSVKHETALVNPDSFGIRAKKTKEQLAELKVSYLKNQFPHDSEIIRLMKITGLTKGEIKKWFSDTRYNQRNSKSNQCLHLNNDSSTTIIIDSSDETTESPTVGTAQPKQSWNPFPDFTPQKFKEKTAEQLRVLQASFLNSSVLTDEELNRLRAQTKLTRREIDAWFTEKKKSKALKEEKMEIDESNAGSSKEEAGETSPADESGAPKSGSTGKICKKTPEQLHMLKSAFVRTQWPSPEEYDKLAKESGLARTDIVSWFGDTRYAWKNGNLKWYYYYQSANSSSMNGLSSLRKRGRGRPKGRGRGRPRGRPRGSKRINNWDRGPSLIKFKTGTAILKDYYLKHKFLNEQDLDELVNKSHMGYEQVREWFAERQRRSELGIELFEENEEEDEVIDDQEEDEEETDDSDTWEPPRHVKRKLSKSDD
"
     misc_feature    743..745
                     /gene="ZHX1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q9UKY1.1); phosphorylation site"
     misc_feature    749..751
                     /gene="ZHX1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q9UKY1.1); phosphorylation site"
     misc_feature    752..754
                     /gene="ZHX1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q9UKY1.1); phosphorylation site"
     misc_feature    1424..2302
                     /gene="ZHX1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9UKY1.1);
                     Region: Required for interaction with NFYA"
     misc_feature    1424..1906
                     /gene="ZHX1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9UKY1.1);
                     Region: Required for dimerization"
     misc_feature    1475..1477
                     /gene="ZHX1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    <1517..1639
                     /gene="ZHX1"
                     /note="Homeodomain;  DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:28970"
     misc_feature    1517..1519
                     /gene="ZHX1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    order(1532..1534,1550..1552,1589..1591,1595..1600,
                     1607..1612,1616..1624,1628..1633)
                     /gene="ZHX1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:28970"
     misc_feature    order(1598..1600,1607..1612,1619..1621)
                     /gene="ZHX1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:28970"
     misc_feature    2012..2179
                     /gene="ZHX1"
                     /note="Homeodomain;  DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:28970"
     misc_feature    order(2012..2017,2021..2023,2072..2074,2090..2092,
                     2129..2131,2135..2140,2147..2152,2156..2164,2168..2173)
                     /gene="ZHX1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:28970"
     misc_feature    order(2018..2020,2138..2140,2147..2152,2159..2161)
                     /gene="ZHX1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:28970"
     misc_feature    2315..>2458
                     /gene="ZHX1"
                     /note="Homeodomain;  DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:28970"
     misc_feature    order(2315..2329,2333..2335,2384..2386,2402..2404,
                     2441..2443,2447..2452)
                     /gene="ZHX1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:28970"
     misc_feature    order(2321..2323,2330..2332,2450..2452)
                     /gene="ZHX1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:28970"
     misc_feature    2552..2554
                     /gene="ZHX1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q9UKY1.1); phosphorylation site"
     misc_feature    2552..2554
                     /gene="ZHX1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    2603..2761
                     /gene="ZHX1"
                     /note="Homeodomain;  DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:28970"
     misc_feature    order(2603..2605,2609..2611,2660..2662,2678..2680,
                     2717..2719,2723..2728,2735..2740,2744..2752,2756..2761)
                     /gene="ZHX1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:28970"
     misc_feature    order(2606..2608,2726..2728,2735..2740,2747..2749)
                     /gene="ZHX1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:28970"
     misc_feature    2654..2656
                     /gene="ZHX1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    2810..2914
                     /gene="ZHX1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9UKY1.1);
                     Region: Required for nuclear localization"
     misc_feature    2954..3085
                     /gene="ZHX1"
                     /note="Homeodomain;  DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:28970"
     misc_feature    order(2990..2992,3008..3010,3047..3049,3053..3058,
                     3065..3070,3074..3082)
                     /gene="ZHX1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:28970"
     misc_feature    order(3056..3058,3065..3070,3077..3079)
                     /gene="ZHX1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:28970"
     misc_feature    3101..3229
                     /gene="ZHX1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9UKY1.1);
                     Region: Required for repressor activity"
     STS             646..784
                     /gene="ZHX1"
                     /standard_name="WI-11363"
                     /db_xref="UniSTS:69740"
     exon            3236..5106
                     /gene="ZHX1"
                     /inference="alignment:Splign:1.39.8"
     STS             3413..3662
                     /gene="ZHX1"
                     /standard_name="STS-T66784"
                     /db_xref="UniSTS:55045"
     variation       3718..3719
                     /gene="ZHX1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1966863"
     STS             3779..3927
                     /gene="ZHX1"
                     /standard_name="D8S1558"
                     /db_xref="UniSTS:153699"
     STS             3786..3910
                     /gene="ZHX1"
                     /standard_name="G30158"
                     /db_xref="UniSTS:61217"
     STS             4498..4732
                     /gene="ZHX1"
                     /standard_name="STS-D60292"
                     /db_xref="UniSTS:50610"
     STS             4537..4726
                     /gene="ZHX1"
                     /standard_name="RH78355"
                     /db_xref="UniSTS:71683"
     polyA_signal    4789..4794
                     /gene="ZHX1"
     variation       4810
                     /gene="ZHX1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1869248"
     polyA_site      4813
                     /gene="ZHX1"
     polyA_signal    5076..5081
                     /gene="ZHX1"
     polyA_site      5106
                     /gene="ZHX1"
ORIGIN      
gacgcgcgcgcgggagggccccgccttggccggctctctcccttccccctccgcccccggacggccgctggggcgcgcgcctctcctcgcacccccaccctgagtccccacactccgcggggccaccgagctgctgaggcccctttgcgggcccgccgagcggttccgggtttagggttcacaggtcagagttgactccctgaaaagtgcagccggtttgaaatgcaagatggcggcggcgtggcgctgagaggcgcggcggcccctgcaggagaagacagactgctgctttggacctgttggtaatgatggcctgagctaaacatctaactagaagggatacccttccatttcaaagaacagaatgctaaggaagctgtggcaagtgattggagttgtgcttcaaaaatttcagaaattcagcagtattttatctgccaacaataagctctttacttgattgcaccatgagaaagctgctaatgagacttgttgagcacaaaaatggacttgaagaaccaaaagccattgttttcaaatgaagaacactgaacagttttaagcctcgatgctttttaatcaccactgagcttttcctcataacatcagaatggcaagcaggcgaaaatcaacaacaccttgcatggtccttgccagtgaacaagatccagaccttgagttgatatcagatttggatgaaggtcctcctgtgcttacacctgtagaaaacaccagagcagagagtatctcaagtgatgaagaggttcatgaatctgtggattcagacaatcagcaaaataaaaaagttgaaggtggatatgaatgtaaatattgtacttttcaaactccagatctaaatatgtttacttttcatgtggattcggaacatcccaatgtagtgctaaattcatcctatgtttgtgtcgaatgcaattttcttaccaaaaggtatgatgcactttctgagcataatctgaaatatcacccaggagaagagaattttaagttgactatggtgaaacgtaataaccagacaatctttgaacaaacaataaatgatctgacttttgatggtagttttgttaaagaggagaatgcagagcaagcagaatctacagaagtttcttcttcgggaatatctatcagtaaaactcctatcatgaaaatgatgaaaaataaagtggaaaataaacggattgcagttcatcataactcagttgaggacgttcctgaagagaaagagaatgaaatcaaaccagaccgtgaagaaattgtagaaaatccaagttcttcagcttctgaatctaatacaagtacttccattgtaaacagaatacatccaagtactgccagcacggtagtgacaccagcagcagttcttcctggattggcacaggtgataactgctgtatctgctcagcagaattctaatttgattcccaaagtcttaatccctgttaatagcattcccacctacaatgctgcattggataacaatccccttttacttaacacctacaacaagttcccttacccaacaatgtcagaaattacagttctttctgctcaagcaaaatatacagaggaacagatcaagatatggttttcagcccaacgtttaaaacatggtgttagttggactcccgaggaagtagaggaggcaagaaggaaacaattcaatggaacagtgcatactgtacctcagaccataactgttattcctacacacatttccacagggagtaatggtttaccatctattttacagacatgccaaatagttggtcagcctggtctggtccttactcaagtggctggaacaaacaccttgccagttacagcacctatagccttgacagtggcaggcgttccaagtcaaaataatatacagaaaagtcaggtacctgctgctcagcctactgcagaaacaaagccagcaacagcagcagttccaacttctcaaagtgtcaaacatgaaactgcattggtaaaccctgattcatttggcattcgggcaaaaaagacaaaagagcaactggcagaattaaaagttagctaccttaaaaatcagtttccccatgattcagaaattatcagacttatgaaaataacaggcctgacgaaaggagagattaaaaaatggtttagtgacacaaggtacaaccagagaaattcaaagagtaatcagtgcttacatctcaacaatgattcctctaccaccattattatagactccagtgatgaaaccacggaatccccaactgttggtactgcacagcctaagcaatcctggaatccttttcctgactttactccccaaaagtttaaagagaaaactgcagagcagcttcgtgtccttcaggcaagttttctcaacagctctgtacttacagatgaagaattaaataggttaagggcacaaaccaaacttaccagaagagaaatcgatgcttggtttacagagaagaagaaatcaaaagctttaaaggaagagaaaatggaaatagatgaaagtaatgcaggtagttccaaagaagaagctggagaaacttctcctgcagatgaatctggtgcacctaagtcagggagtacaggcaagatatgtaaaaaaacacctgagcagctgcacatgcttaagagtgcatttgtccggacacagtggccatcaccagaagagtatgacaagttggccaaagaaagcgggcttgctagaacagacatagttagttggtttggggacacccgttatgcttggaagaatggaaacttgaaatggtactactactatcagagcgccaattcaagtagtatgaatggtctgtcttcccttaggaaaagagggagagggagacccaaaggacggggaagaggaagaccgcgtgggcggcctagaggaagcaaaagaattaacaactgggacaggggaccatcactcataaaatttaaaactggaactgcaatacttaaggattattacctgaagcacaagtttcttaatgagcaagaccttgatgaacttgttaacaaatcacatatgggctatgagcaggtcagagagtggtttgcagaaagacagagaagatcagaattaggtatagaattatttgaggaaaatgaggaggaagatgaagttattgatgaccaggaagaggatgaagaagaaacagatgatagtgacacttgggaacctccacgacatgtgaaacggaagctgtctaaatcagatgactgaaatctgcctaaaacgttgaaggagaatcaattcttcaactcaagatgtctgatttactgtgaatttgcccaatctttgatgacattgaaaacgttttggggcatacacactcaaaaagcaggatccaatacccaaaagaaatggaacttaatgttgtgccaaagttaaactactgcagttggtggaagttctgcaatgtaaatagaacactaattaaaaaacaacttgtaaaaatgcaatttaaattttaatacagtacatttttcttctaatatgatggagacattctgaatcttagactttctgagggggtttaatgaccactagagcttgtcctcatattcagtccagtttaatactgtatgtctagtaagatgggctatatattgcctctattctttgagatgtgattaagcttagaactttgaccaaaaattttacagtaaaaattgttagaaatgggtaaaaaaaaaaaaaaaaaaaaaaccctgatttattactatgtcttatttatcagaccctgcactaagattaaaagttgtgcatgggcttatacaatttcaaatgtaaaaacagcctatttatatatgttgaaacaataagattttatggtttcactggcccttaataattggatccttcattaaacacatccatgaataccactgtttctactgttacttgttccattagaagctgatttgctttttattaaactgcaggaaattaattctgaagaaggaaaagaaactgacatggtaatttggatagggtgaagctttgaaataaatactgcaccaaaaatgtgaaaaagaatcacgtagtaaatgtatacttagtgttttcttacaatcgtggaaatcagaaatgtttatacaggtgtcagatcagaatttttaagagttatctttcagtgaaattttataacagtttcagtgaatagagaaaaaattctgaactgatcataatgagttaaaagttagcttttcacttatgaatcatgggagtgttaactgttaactcttgccgtatcaggagactgaaagttcatactaatttacaaactttgtaaagactggtgctgttcattcatattgggaagaaccctttcttttgtgaccataggaccatttttcaaaatgcgctttcttcgtagaagaaatgttcagtttaattagctttggattttaacatgtttttctgaatgaccagatgtaggcttagccagtttattttctctaatttaatggataataaatattaagctcttggttaaatgtttttcagccattgaaaatgttatgaaaaagccttgaatatgcatgctgctttcatttttataaactttttattttttaactatagctttattagtaattccaaaatgctgcaatgtagctgatttcctcactcagacagctggctttgtgggtggcttttttcatactactgttaacttttttaaaaaagaagcaatgtaaagaccgtaatgcactaagctttttttttttcttttacacgtttaaaaacttcttaaagcactctgtaatataatgattaaattgctcccttttataaacattgctaatgtggtctgagttttgtttgacaataattttaatgttctcaaaatttgaaatgtcaagtattagaaatgaagcctttgaatatagttgtttcccttgcaatatgttaactctgtgtagctgtatataactattaatttccctcatctcttttataggcctgataaaactcttctctgacgtttgctagcttttaaatatatttatttgacagagcaaaagaaccctcttctggttgattgtgaccttgaatacaaaataaaagtagtgattagtagtttacagtgaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:11244 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IDA
            GeneID:11244 -> Molecular function: GO:0003714 [transcription corepressor activity] evidence: IDA
            GeneID:11244 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:11244 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IEA
            GeneID:11244 -> Molecular function: GO:0046872 [metal ion binding] evidence: IEA
            GeneID:11244 -> Molecular function: GO:0046982 [protein heterodimerization activity] evidence: IDA
            GeneID:11244 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IDA
            GeneID:11244 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
            GeneID:11244 -> Biological process: GO:0030154 [cell differentiation] evidence: IEA
            GeneID:11244 -> Biological process: GO:0045892 [negative regulation of transcription, DNA-dependent] evidence: IDA
            GeneID:11244 -> Cellular component: GO:0005634 [nucleus] evidence: IDA

by @meso_cacase at DBCLS
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