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2024-04-20 09:05:26, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_007184 5252 bp mRNA linear PRI 11-MAY-2013
DEFINITION Homo sapiens nischarin (NISCH), transcript variant 1, mRNA.
ACCESSION NM_007184
VERSION NM_007184.3 GI:144953896
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5252)
AUTHORS Mukaddam-Daher,S.
TITLE An 'I' on cardiac hypertrophic remodelling: imidazoline receptors
and heart disease
JOURNAL Can J Cardiol 28 (5), 590-598 (2012)
PUBMED 22483786
REMARK GeneRIF: Imidazoline receptor 1 gene plays a role in the
development of cardiac hypertrophy and ventirular remodeling.
Review article
REFERENCE 2 (bases 1 to 5252)
AUTHORS Baranwal,S., Wang,Y., Rathinam,R., Lee,J., Jin,L., McGoey,R.,
Pylayeva,Y., Giancotti,F., Blobe,G.C. and Alahari,S.K.
TITLE Molecular characterization of the tumor-suppressive function of
nischarin in breast cancer
JOURNAL J. Natl. Cancer Inst. 103 (20), 1513-1528 (2011)
PUBMED 21917605
REMARK GeneRIF: Nischarin reduces alpha5 integrin expression leading to
reduction of FAK phosphorylation and Rac GTP loading, which in turn
reduces tumor growth. NISCH also regulates PAK and LIMK signaling.
REFERENCE 3 (bases 1 to 5252)
CONSRTM Psychiatric GWAS Consortium Bipolar Disorder Working Group
TITLE Large-scale genome-wide association analysis of bipolar disorder
identifies a new susceptibility locus near ODZ4
JOURNAL Nat. Genet. 43 (10), 977-983 (2011)
PUBMED 21926972
REMARK Erratum:[Nat Genet. 2012 Sep;44(9):1072. Fullerton, Janice M
[added]; Hyoun, Phil L [corrected to Lee, Phil H]; Meng, Fan Guo
[corrected to Meng, Fan]]
Publication Status: Online-Only
REFERENCE 4 (bases 1 to 5252)
AUTHORS Bailey,S.D., Xie,C., Do,R., Montpetit,A., Diaz,R., Mohan,V.,
Keavney,B., Yusuf,S., Gerstein,H.C., Engert,J.C. and Anand,S.
CONSRTM DREAM investigators
TITLE Variation at the NFATC2 locus increases the risk of
thiazolidinedione-induced edema in the Diabetes REduction
Assessment with ramipril and rosiglitazone Medication (DREAM) study
JOURNAL Diabetes Care 33 (10), 2250-2253 (2010)
PUBMED 20628086
REMARK GeneRIF: Observational study of gene-disease association,
gene-environment interaction, and pharmacogenomic / toxicogenomic.
(HuGE Navigator)
REFERENCE 5 (bases 1 to 5252)
AUTHORS Talmud,P.J., Drenos,F., Shah,S., Shah,T., Palmen,J., Verzilli,C.,
Gaunt,T.R., Pallas,J., Lovering,R., Li,K., Casas,J.P., Sofat,R.,
Kumari,M., Rodriguez,S., Johnson,T., Newhouse,S.J., Dominiczak,A.,
Samani,N.J., Caulfield,M., Sever,P., Stanton,A., Shields,D.C.,
Padmanabhan,S., Melander,O., Hastie,C., Delles,C., Ebrahim,S.,
Marmot,M.G., Smith,G.D., Lawlor,D.A., Munroe,P.B., Day,I.N.,
Kivimaki,M., Whittaker,J., Humphries,S.E. and Hingorani,A.D.
CONSRTM ASCOT investigators; NORDIL investigators; BRIGHT Consortium
TITLE Gene-centric association signals for lipids and apolipoproteins
identified via the HumanCVD BeadChip
JOURNAL Am. J. Hum. Genet. 85 (5), 628-642 (2009)
PUBMED 19913121
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 6 (bases 1 to 5252)
AUTHORS Piletz,J.E., Deleersnijder,W., Roth,B.L., Ernsberger,P., Zhu,H. and
Ziegler,D.
TITLE IRAS splice variants
JOURNAL Ann. N. Y. Acad. Sci. 1009, 419-426 (2003)
PUBMED 15028621
REMARK GeneRIF: Results describe three alternatively spliced transcripts
of the human I(1)-imidazoline receptor candidate gene, IRAS.
REFERENCE 7 (bases 1 to 5252)
AUTHORS El-Ayoubi,R., Gutkowska,J., Regunathan,S. and Mukaddam-Daher,S.
TITLE Imidazoline receptors in the heart: characterization, distribution,
and regulation
JOURNAL J. Cardiovasc. Pharmacol. 39 (6), 875-883 (2002)
PUBMED 12021582
REMARK GeneRIF: The heart possesses imidazoline I1-receptors that are
up-regulated in the presence of hypertension or heart failure,
which suggests their involvement in cardiovascular regulation.
REFERENCE 8 (bases 1 to 5252)
AUTHORS Alahari,S.K., Lee,J.W. and Juliano,R.L.
TITLE Nischarin, a novel protein that interacts with the integrin alpha5
subunit and inhibits cell migration
JOURNAL J. Cell Biol. 151 (6), 1141-1154 (2000)
PUBMED 11121431
REFERENCE 9 (bases 1 to 5252)
AUTHORS Piletz,J.E., Ivanov,T.R., Sharp,J.D., Ernsberger,P., Chang,C.H.,
Pickard,R.T., Gold,G., Roth,B., Zhu,H., Jones,J.C., Baldwin,J. and
Reis,D.J.
TITLE Imidazoline receptor antisera-selected (IRAS) cDNA: cloning and
characterization
JOURNAL DNA Cell Biol. 19 (6), 319-329 (2000)
PUBMED 10882231
REFERENCE 10 (bases 1 to 5252)
AUTHORS Ivanov,T.R., Jones,J.C., Dontenwill,M., Bousquet,P. and Piletz,J.E.
TITLE Characterization of a partial cDNA clone detected by imidazoline
receptor-selective antisera
JOURNAL J. Auton. Nerv. Syst. 72 (2-3), 98-110 (1998)
PUBMED 9851558
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DB496030.1, AC006208.3,
BC038102.2 and AI889216.1.
This sequence is a reference standard in the RefSeqGene project.
On Apr 11, 2007 this sequence version replaced gi:66472381.
Summary: This gene encodes a nonadrenergic imidazoline-1 receptor
protein that localizes to the cytosol and anchors to the inner
layer of the plasma membrane. The orthologous mouse protein has
been shown to influence cytoskeletal organization and cell
migration by binding to alpha-5-beta-1 integrin. In humans, this
protein has been shown to bind to the adapter insulin receptor
substrate 4 (IRS4) to mediate translocation of alpha-5 integrin
from the cell membrane to endosomes. Expression of this protein was
reduced in human breast cancers while its overexpression reduced
tumor growth and metastasis; possibly by limiting the expression of
alpha-5 integrin. In human cardiac tissue, this gene was found to
affect cell growth and death while in neural tissue it affected
neuronal growth and differentiation. Alternative splicing results
in multiple transcript variants encoding differerent isoforms. Some
isoforms lack the expected C-terminal domains of a functional
imidazoline receptor. [provided by RefSeq, Jan 2013].
Transcript Variant: This variant (1) represents the longest
transcript and encodes the longest isoform (1; also known as
IRAS-M).
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC054494.1, AF082516.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025082 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: full length.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-40 DB496030.1 1-40
41-96 AC006208.3 63988-64043
97-340 BC038102.2 1-244
341-341 AC006208.3 67131-67131
342-3300 BC038102.2 246-3204
3301-3501 AC006208.3 97829-98029
3502-5028 BC038102.2 3406-4932
5029-5230 AC006208.3 101302-101503
5231-5252 AI889216.1 1-22 c
FEATURES Location/Qualifiers
source 1..5252
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3p21.1"
gene 1..5252
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/note="nischarin"
/db_xref="GeneID:11188"
/db_xref="HGNC:18006"
exon 1..227
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 31
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:111321670"
variation 41
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="t"
/db_xref="dbSNP:968588"
variation 48
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:368162215"
variation 58
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="g"
/replace="t"
/db_xref="dbSNP:377686080"
misc_feature 96..98
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/note="upstream in-frame stop codon"
variation 104
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="g"
/replace="t"
/db_xref="dbSNP:1319202"
variation 124
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:11719772"
CDS 135..4649
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/note="isoform 1 is encoded by transcript variant 1; I-1
receptor candidate protein; imidazoline receptor antisera
selected; I1R candidate protein; imidazoline receptor 1"
/codon_start=1
/product="nischarin isoform 1"
/protein_id="NP_009115.2"
/db_xref="GI:66472382"
/db_xref="CCDS:CCDS33767.1"
/db_xref="GeneID:11188"
/db_xref="HGNC:18006"
/translation="
MATARTFGPEREAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKLVAERKIDKNLLPPKKIIGKNSRSLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLHFHFYEINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKPTLATLSVRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSISEIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTLNLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDYRTKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLSAAPCIRPSSSPPTVAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGCSDSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRLSTLIRQAIERQLPAWIEAANQREEGQGEQGEEEDEEEEEEEDVAENRYFEMGPPDVEEEEGGGQGEEEEEEEEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGSIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLVLKVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLTFYKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEAVKSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLQDLKTVVIAKTPGTGGSPQGSFADGQPAERRASNDQRPQEVPAEALAPAPAEVPAPAPAAASASGPAKTPAPAEASTSALVPEETPVEAPAPPPAEAPAQYPSEHLIQATSEENQIPSHLPACPSLRHVASLRGSAIIELFHSSIAEVENEELRHLMWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYFSEPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVNVGLFDQHFRLTGSTPMQVVTCLTRDSYLTHCFLQHLMVVLSSLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTYPSEEEIGDLTFTVAQKMAEPEKAPALSILLYVQAFQVGMPPPGCCRGPLRPKTLLLTSSEIFLLDEDCVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQGHDLMGSVTLDHFGEVPGGPARASQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPVELTG
"
misc_feature 135..533
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y2I1.3);
Region: Necessary for binding to phosphoinositide-3-P, not
sufficient for targeting to endosomes"
misc_feature 195..521
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/note="The phosphoinositide binding Phox Homology domain
of the Imidazoline Receptor Antisera-Selected; Region:
PX_IRAS; cd06875"
/db_xref="CDD:132785"
misc_feature order(279..287,354..359,396..398)
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/note="phosphoinositide binding site [chemical binding];
other site"
/db_xref="CDD:132785"
misc_feature 492..2219
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y2I1.3);
Region: Necessary for homooligomerization and targeting to
endosomes"
misc_feature 867..2741
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y2I1.3);
Region: Interaction with PAK1 (By similarity)"
misc_feature <996..1379
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/note="Leucine-rich repeats (LRRs), ribonuclease inhibitor
(RI)-like subfamily. LRRs are 20-29 residue sequence
motifs present in many proteins that participate in
protein-protein interactions and have different functions
and cellular locations. LRRs correspond...; Region:
LRR_RI; cl15309"
/db_xref="CDD:199167"
misc_feature order(999..1001,1008..1010,1014..1016,1023..1025,
1029..1031,1068..1070,1077..1079,1083..1085,1092..1094,
1098..1100,1134..1136,1143..1145,1149..1151,1158..1160,
1164..1166,1203..1205,1212..1214,1218..1220,1227..1229,
1233..1235,1269..1271,1278..1280,1284..1286,1293..1295,
1299..1301,1344..1346,1353..1355,1359..1361,1368..1370,
1374..1376)
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/note="Leucine-rich repeats; other site"
/db_xref="CDD:29015"
misc_feature order(1020..1022,1089..1091,1224..1226,1281..1283,
1287..1289,1356..1358)
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/note="Substrate binding site [chemical binding]; other
site"
/db_xref="CDD:29015"
misc_feature 1062..1184
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/note="Leucine Rich repeats (2 copies); Region: LRR_4;
pfam12799"
/db_xref="CDD:205079"
misc_feature 1131..1301
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/note="Leucine rich repeat; Region: LRR_8; pfam13855"
/db_xref="CDD:206026"
misc_feature 2112..2741
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y2I1.3);
Region: Interaction with LIMK (By similarity)"
misc_feature 2259..2555
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y2I1.3);
Region: Interaction with ITGA5 (By similarity)"
misc_feature 3984..3986
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9Y2I1.3); phosphorylation site"
variation 152
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace=""
/replace="c"
/db_xref="dbSNP:35134540"
exon 228..311
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 240
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:373680961"
variation 259
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:376872356"
exon 312..494
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 314
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:140873050"
variation 315
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:140213598"
variation 341
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:1541495"
variation 350
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:375129226"
variation 449
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:200818525"
exon 495..543
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 514
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:146890321"
variation 515
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:139351379"
exon 544..707
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 548
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="t"
/db_xref="dbSNP:147461628"
variation 563
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:79469996"
variation 564
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:149595998"
variation 578
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:148675688"
variation 580
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:201162297"
variation 603
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:183915749"
variation 607
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:202168458"
variation 638
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:146742349"
variation 649
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:143979580"
variation 659
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:150124723"
variation 674
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="c"
/db_xref="dbSNP:145517380"
exon 708..803
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 747
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:201085571"
variation 756
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:146818112"
variation 762
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:147030604"
variation 764
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:148100246"
variation 777
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:139780692"
exon 804..899
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 807
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="c"
/db_xref="dbSNP:141707381"
variation 823
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:144172612"
variation 836
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:56114678"
variation 842
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:370837747"
variation 843
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:141246499"
variation 847
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:147937807"
variation 848
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:76608301"
variation 854
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:61134406"
variation 857
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:183032337"
variation 876
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:199663460"
exon 900..1052
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 920
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:200589931"
variation 921
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="t"
/db_xref="dbSNP:148320456"
variation 977
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:60805368"
variation 978
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:199545023"
variation 983
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:142571978"
variation 1006
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:372082480"
variation 1007
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:375370492"
variation 1008
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:200763699"
variation 1025
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:139638387"
variation 1029
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:9856575"
variation 1037
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="g"
/replace="t"
/db_xref="dbSNP:372476563"
variation 1040
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:61738410"
variation 1041
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:142925971"
variation 1043
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:377168283"
exon 1053..1121
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 1095
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:372936271"
exon 1122..1307
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 1163
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:367571268"
variation 1166
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:374743785"
variation 1171
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:141115377"
variation 1242
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:376921326"
variation 1249
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:138837125"
variation 1255
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:201701090"
variation 1270
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:145669901"
variation 1278
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:374630439"
variation 1295
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:199949923"
variation 1302
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:142530239"
exon 1308..1436
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 1320
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:200373254"
variation 1327
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:148269171"
variation 1350
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:369255705"
variation 1353
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:111273639"
variation 1364
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:372950011"
variation 1381
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="g"
/replace="t"
/db_xref="dbSNP:145041762"
variation 1418
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:140425464"
exon 1437..1550
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 1491
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:11553556"
variation 1495
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:372042714"
variation 1513
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:78900486"
variation 1550
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:146880575"
exon 1551..1662
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 1552
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace=""
/replace="g"
/db_xref="dbSNP:35710897"
variation 1622
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:71297399"
variation 1624
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="c"
/db_xref="dbSNP:375016559"
variation 1631
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:201131163"
variation 1634
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:200065466"
variation 1652
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:183152498"
exon 1663..1787
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 1701
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:138615970"
variation 1706
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:146279257"
variation 1721
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:376637823"
variation 1727
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:202191902"
variation 1747
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:143392261"
variation 1780
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:369875480"
exon 1788..1837
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 1789
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:145370808"
variation 1796
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:150663893"
variation 1830
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:149825786"
variation 1833
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:200274069"
exon 1838..3247
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 1850
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:139766391"
variation 1874
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:369122107"
variation 1912
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:201303141"
variation 1922
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:146555783"
variation 1946
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:370944443"
variation 1958
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:374298617"
variation 1981
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:368651371"
variation 2006
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:61737029"
variation 2015
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="g"
/replace="t"
/db_xref="dbSNP:11721104"
variation 2046
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:140252201"
variation 2079
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="g"
/replace="t"
/db_xref="dbSNP:138175917"
variation 2118
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:145761574"
variation 2129
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:149246699"
variation 2148
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:148434820"
variation 2162
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:371082984"
variation 2175
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:146374405"
variation 2181
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:374588018"
variation 2184
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:201343452"
variation 2186
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:62639325"
variation 2219
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:368096988"
variation 2222
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:139671304"
variation 2250
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:372251478"
variation 2336
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:375540569"
variation 2337
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:145748458"
variation 2342
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:147047557"
variation 2351
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:369874506"
variation 2373
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="c"
/db_xref="dbSNP:62256878"
variation 2383
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:200813753"
variation 2424
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:111620540"
variation 2425
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:148273093"
variation 2432
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:373385160"
variation 2442
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:377264711"
variation 2444
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:368725603"
variation 2457
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:373245036"
variation 2462
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:377489314"
variation 2465
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:370475843"
variation 2468
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:150301138"
variation 2491
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:142485648"
variation 2503
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:138446881"
variation 2519
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:144366169"
variation 2523
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:142256480"
variation 2528
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:200281337"
variation 2537
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:371303104"
variation 2546
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:17052200"
variation 2547
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:142117162"
variation 2585
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:138392739"
variation 2641
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:367898298"
variation 2699
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:370316749"
variation 2705
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:374253267"
variation 2717
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="c"
/db_xref="dbSNP:77768459"
variation 2731
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="g"
/replace="t"
/db_xref="dbSNP:368842942"
variation 2745
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:138593477"
variation 2764
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:150671822"
variation 2765
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="c"
/db_xref="dbSNP:138936894"
variation 2771
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:139825323"
variation 2774
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:374460369"
variation 2789
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:112323499"
variation 2790
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:368653205"
variation 2801
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:370031657"
variation 2802
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:373709550"
variation 2808
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:145350144"
variation 2809
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:201933512"
variation 2820
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:144392121"
variation 2822
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:113789685"
variation 2825
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:371639899"
variation 2843
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:201307683"
variation 2844
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:139197623"
variation 2847
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:372469950"
variation 2849
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:145102328"
variation 2863..2864
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace=""
/replace="gggggg"
/db_xref="dbSNP:146952334"
variation 2865
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="g"
/replace="t"
/db_xref="dbSNP:200548649"
variation 2900
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:190227680"
variation 2914
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:17857460"
variation 2922
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:201390995"
variation 2923
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:150644559"
variation 2927
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:140308061"
variation 2941
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:377164178"
variation 2946
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:200010476"
variation 2966
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:369952066"
variation 2974
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:182689590"
variation 3003
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:141525236"
variation 3027
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:138562238"
variation 3041
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:372911860"
variation 3044
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:61739223"
variation 3069
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:201907343"
variation 3089
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:61743106"
variation 3101
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:147254290"
variation 3106
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:369234988"
variation 3120
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:200965700"
variation 3122
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:144542629"
variation 3123
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:372817454"
variation 3139
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:200440036"
variation 3181
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:142618964"
variation 3191
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:374429650"
variation 3195
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:377196388"
variation 3217
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:61736838"
variation 3220
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="t"
/db_xref="dbSNP:370066214"
variation 3228
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:377705799"
variation 3238
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:371017818"
exon 3248..3590
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 3258
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:370743908"
variation 3292
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:373807549"
variation 3293
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:146259914"
variation 3296
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:200959264"
variation 3301
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:887515"
variation 3310
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:199584023"
variation 3403
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:61729066"
variation 3404
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:13315631"
variation 3434
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:144124967"
variation 3435
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:370428956"
variation 3454
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:146356041"
variation 3455
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:200619504"
variation 3475
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:201610888"
variation 3501
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:17857153"
variation 3502
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:200762525"
variation 3503
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="g"
/replace="t"
/db_xref="dbSNP:373167783"
variation 3521
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:141420336"
variation 3524
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="g"
/replace="t"
/db_xref="dbSNP:374595197"
variation 3529
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:376126677"
variation 3563
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:149501368"
exon 3591..3747
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 3611
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:200002810"
variation 3612
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:368392147"
variation 3628
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:139961321"
variation 3659
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:199800809"
variation 3662
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:372651693"
variation 3672
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:146180879"
variation 3676
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:148389771"
variation 3704
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="g"
/replace="t"
/db_xref="dbSNP:150948031"
variation 3713
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:200756811"
variation 3714
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:372980592"
variation 3720
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:376177004"
exon 3748..3876
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 3770
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:377533055"
variation 3781
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:200423743"
variation 3809
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:370062594"
variation 3821
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:150029838"
variation 3842
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:146892996"
variation 3854
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:41292366"
variation 3867
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:202010087"
exon 3877..4038
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 3908
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:368243024"
variation 3911
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:148110008"
STS 3919..4264
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/standard_name="MARC_5975-5976:997299498:1"
/db_xref="UniSTS:269627"
variation 3975
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:199747952"
variation 3985
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:201322926"
variation 3986
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:372434074"
variation 4014..4015
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace=""
/replace="t"
/db_xref="dbSNP:34585484"
variation 4016
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:374481892"
exon 4039..5239
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/inference="alignment:Splign:1.39.8"
variation 4059
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:199861420"
variation 4074
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:200063553"
variation 4075
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="g"
/replace="t"
/db_xref="dbSNP:201606509"
variation 4085
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:146000115"
variation 4091
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:371582497"
variation 4107
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:200062389"
variation 4121
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:374984310"
variation 4162
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:369447186"
variation 4179
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:202036631"
variation 4184
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:188816312"
variation 4187
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:373644936"
variation 4229
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:375734773"
variation 4235
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:370065087"
variation 4239
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:114899589"
variation 4259
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:112341632"
variation 4267
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:139206974"
variation 4278
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:17857443"
variation 4280
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:200860167"
variation 4314
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:369843789"
variation 4322
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="c"
/db_xref="dbSNP:192271081"
variation 4328
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:61743076"
variation 4334
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:201159290"
variation 4345
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:3180422"
variation 4351
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:373042665"
variation 4359
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:144348444"
variation 4366
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:142490807"
variation 4386
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:376926446"
variation 4414
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:144845982"
variation 4430
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:61737697"
variation 4466
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:373550450"
variation 4468
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:377582481"
variation 4523
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="g"
/replace="t"
/db_xref="dbSNP:117164680"
variation 4545
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="g"
/replace="t"
/db_xref="dbSNP:149163189"
variation 4546
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="g"
/replace="t"
/db_xref="dbSNP:200239033"
variation 4569
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:138882217"
variation 4586
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:370820504"
variation 4597
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:375144185"
variation 4621
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:200437523"
variation 4641
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:12495998"
variation 4643
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:370623437"
variation 4671
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:375096283"
variation 4683
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="g"
/replace="t"
/db_xref="dbSNP:78178109"
variation 4685
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:371308963"
variation 4686
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:2240897"
variation 4693
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:141019693"
variation 4728
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="g"
/replace="t"
/db_xref="dbSNP:144833808"
variation 4895
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:113079829"
variation 4935
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:190345415"
variation 4952
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="g"
/db_xref="dbSNP:147954954"
variation 4969
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="t"
/db_xref="dbSNP:1802448"
variation 4983
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:182586852"
variation 4994..4999
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace=""
/replace="tgttgc"
/db_xref="dbSNP:71770895"
variation 4999..5004
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace=""
/replace="ctgttg"
/db_xref="dbSNP:60665579"
variation 5019..5024
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace=""
/replace="gttgct"
/db_xref="dbSNP:71864354"
variation 5020..5025
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace=""
/replace="ttgctg"
/db_xref="dbSNP:72335009"
variation 5021..5026
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace=""
/replace="tgctgt"
/db_xref="dbSNP:71664531"
STS 5039..5189
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/standard_name="RH17807"
/db_xref="UniSTS:51483"
variation 5074
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:79718450"
STS 5081..5214
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/standard_name="SHGC-32372"
/db_xref="UniSTS:21198"
variation 5088
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="c"
/db_xref="dbSNP:1063079"
variation 5098
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="g"
/db_xref="dbSNP:184121329"
variation 5101
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:1046389"
STS 5106..5232
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/standard_name="WI-18469"
/db_xref="UniSTS:55535"
variation 5175
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="a"
/replace="c"
/db_xref="dbSNP:3186398"
variation 5181
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
/replace="c"
/replace="t"
/db_xref="dbSNP:377044085"
polyA_signal 5212..5217
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
polyA_site 5235
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
polyA_site 5239
/gene="NISCH"
/gene_synonym="hIRAS; I-1; IR1; IRAS"
ORIGIN
aggcggggccaagatggcggcgcagcgcgcggcgggggcgacgggcggcgggggccggggggcggtgggacgttgaccccgccccctgctgctgctagtctgcgccgggcggcggtggcggcggagacccgaacatggcgaccgcgcgcaccttcgggcccgagcgggaagccgagccggccaaggaagcgcgcgtcgtgggctcggagcttgtggacacttatacggtttacatcatccaggtcactgatggcagccatgagtggacagtaaagcaccgctacagcgacttccatgacctgcatgaaaagctcgttgcagagagaaagattgataaaaatctgcttccgcccaaaaagataattgggaaaaactcaagaagcttggtggagaagagggagaaggatctggaggtctacctccagaagctcctggctgccttccctggcgtgacccccagagtactggcccacttcttgcattttcacttctatgagataaatggcatcaccgcggcactggctgaagagctctttgagaaaggagaacagctcctgggggccggcgaggtctttgccattggacccctgcagctgtatgccgtcacggagcagctgcagcagggaaagcccacgtgcgccagtggggatgccaagaccgacctcgggcacatcctggacttcacctgtcgccttaagtaccttaaggtttctggcacagaaggaccttttgggaccagcaacattcaggagcagctcctgccgttcgacctatcaatattcaagtccctgcatcaggtggagataagtcactgtgatgctaagcacatcagagggctggtcgcatcgaagcccaccttagccacgctgagtgtccgcttctcagcaacctcgatgaaggaagtccttgttcctgaagcctcagaatttgatgagtgggagcctgaaggcacaaccctagaaggccctgtgactgccgtcatccccacttggcaggcattgaccacgcttgacctgagccacaacagcatctccgagatcgacgagtctgtgaaactgatcccaaagattgagttcctggacctgagtcacaatggattgctggttgtggacaatctgcagcacctgtataaccttgtgcatctggacctgtcctacaacaagctctcctccttggaagggcttcacaccaagctggggaacatcaagaccttaaacctggcaggcaacctcctagagagtctgagtggcctgcacaagctctactcactggtcaacctggatctccgggacaacaggatcgaacagatggaggaggtccggagcataggcagcctcccgtgtctggagcacgtgtctctgctgaacaaccctctgagcatcatccccgactaccggaccaaggtgctggctcagttcggagagagggcctcagaggtctgtctggatgacacagtgaccacagagaaggagctggacactgtggaagtgctgaaagcaattcagaaagccaaggaggtcaagtccaaactgagcaacccagagaagaagggtggtgaagactcccggctctcagctgccccctgcatcagacccagcagctcccctcccactgtggctcccgcatctgcctccctgccccagcccatcctctctaaccaaggaatcatgttcgttcaggaggaggccctggccagcagcctctcgtccactgacagtctgactcccgagcaccagcccattgcccagggatgttctgattccttggagtccatccctgcgggacaggcagcttccgatgatttaagggacgtgccaggagctgttggtggtgcaagcccagaacatgccgagccggaggtccaggtggtgccggggtctggccagatcatcttcctgcccttcacctgcattggctacacggccaccaatcaggacttcatccagcgcctgagcacactgatccggcaggccatcgagcggcagctgcctgcctggatcgaggctgccaaccagcgggaggagggccagggtgaacagggcgaggaggaggatgaggaggaggaagaagaggaggacgtggctgagaaccgctactttgaaatggggcccccagacgtggaggaggaggagggaggaggccagggggaggaagaggaggaggaagaggaggatgaagaggccgaggaggagcgcctggctctggaatgggccctgggcgcggacgaggacttcctgctggagcacatccgcatcctcaaggtgctgtggtgcttcctgatccatgtgcagggcagtatccgccagttcgccgcctgccttgtgctcaccgacttcggcatcgcagtcttcgagatcccgcaccaggagtctcggggcagcagccagcacatcctctcctccctgcgctttgtcttttgcttcccgcatggcgacctcaccgagtttggcttcctcatgccggagctgtgtctggtgctcaaggtacggcacagtgagaacacgctcttcattatctcggacgccgccaacctgcacgagttccacgcggacctgcgctcatgctttgcaccccagcacatggccatgctgtgtagccccatcctctacggcagccacaccagcctgcaggagttcctgcgccagctgctcaccttctacaaggtggctggcggctgccaggagcgcagccagggctgcttccccgtctacctggtctacagtgacaagcgcatggtgcagacggccgccggggactactcaggcaacatcgagtgggccagctgcacactctgttcagccgtgcggcgctcctgctgcgcgccctctgaggccgtcaagtccgccgccatcccctactggctgttgctcacgccccagcacctcaacgtcatcaaggccgacttcaaccccatgcccaaccgtggcacccacaactgtcgcaaccgcaacagcttcaagctcagccgtgtgccgctctccaccgtgctgctggaccccacacgcagctgtacccagcctcggggcgcctttgctgatggccacgtgctagagctgctcgtggggtaccgctttgtcactgccatcttcgtgctgccccacgagaagttccacttcctgcgcgtctacaaccagctgcgggcctcgctgcaggacctgaagactgtggtcatcgccaagacccccgggacgggaggcagcccccagggctcctttgcggatggccagcctgccgagcgcagggccagcaatgaccagcgtccccaggaggtcccagcagaggctctggccccggccccagcggaagtcccagctccagcccctgcagcagcctcagcctcaggcccagcgaagactccggccccagcagaggcctcaacttcagctttggtcccagaggagacgccagtggaagctccagccccacccccagccgaggcccctgcccagtacccgagtgagcacctcatccaggccacctcggaggagaatcagatcccctcgcacttgcctgcctgcccgtcgctccggcacgtcgccagcctgcggggcagcgccatcatcgagctcttccacagcagcattgctgaggttgaaaacgaggagctgaggcacctcatgtggtcctcggtggtgttctaccagaccccagggctggaggtgactgcctgcgtgctgctctccaccaaggctgtgtactttgtgctccacgacggcctccgccgctacttctcagagccactgcaggatttctggcatcagaaaaacaccgactacaacaacagccctttccacatctcccagtgcttcgtgctaaagcttagtgacctgcagtcagtcaatgtggggcttttcgaccagcatttccggctgacgggttccaccccgatgcaggtggtcacgtgcttgacgcgggacagctacctgacgcactgcttcctccagcacctcatggtcgtgctgtcctctctggaacgcacgccctcgccggagcctgttgacaaggacttctactccgagtttgggaacaagaccacagggaagatggagaactacgagctgatccactctagtcgcgtcaagtttacctaccccagtgaggaggagattggggacctgacgttcactgtggcccaaaagatggctgagccagagaaggccccagccctcagcatcctgctgtacgtgcaggccttccaggtgggcatgccaccccctgggtgctgcaggggccccctgcgccccaagacactcctgctcaccagctccgagatcttcctcctggatgaggactgtgtccactacccactgcccgagtttgccaaagagccgccgcagagagacaggtaccggctggacgatggccgccgcgtccgggacctggaccgagtgctcatgggctaccagacctacccgcaggccctcaccctcgtcttcgatgacgtgcaaggtcatgacctcatgggcagtgtcaccctggaccactttggggaggtgccaggtggcccggctagagccagccagggccgtgaagtccagtggcaggtgtttgtccccagtgctgagagcagagagaagctcatctcgctgttggctcgccagtgggaggccctgtgtggccgtgagctgcctgtcgagctcaccggctagcccaggccacagccagcctgtcgtgtccagcctgacgcctactggggcagggcagcaggcttttgtgttctctaaaaatgttttatcctccctttggtaccttaatttgactgtcctcgcagagaatgtgaacatgtgtgtgtgttgtgttaattctttctcatgttgggagtgagaatgccgggcccctcagggctgtcggtgtgctgtcagcctcccacaggtggtacagccgtgcacaccagtgtcgtgtctgctgttgtgggaccgttgttaacacgtgacactgtgggtctgactttctcttctacacgtcctttcctgaagtgtcgagtccagtcctttgttgctgttgctgttgctgttgctgttgctgttgctgttggcatcttgctgctaatcctgaggctggtagcagaatgcacattggaagctcccaccccatattgttcttcaaagtggaggtctcccctgatccagacaagtgggagagcccgtgggggcaggggacctggagctgccagcaccaagcgtgattcctgctgcctgtattctctattccaataaagcagagtttgacaccgtctgcaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:11188 -> Molecular function: GO:0005178 [integrin binding] evidence: IEA
GeneID:11188 -> Molecular function: GO:0008227 [G-protein coupled amine receptor activity] evidence: IEA
GeneID:11188 -> Molecular function: GO:0035091 [phosphatidylinositol binding] evidence: IEA
GeneID:11188 -> Biological process: GO:0006006 [glucose metabolic process] evidence: IEA
GeneID:11188 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:11188 -> Biological process: GO:0008217 [regulation of blood pressure] evidence: IEA
GeneID:11188 -> Biological process: GO:0016601 [Rac protein signal transduction] evidence: IEA
GeneID:11188 -> Biological process: GO:0030036 [actin cytoskeleton organization] evidence: IEA
GeneID:11188 -> Biological process: GO:0030336 [negative regulation of cell migration] evidence: IEA
GeneID:11188 -> Biological process: GO:0032228 [regulation of synaptic transmission, GABAergic] evidence: IEA
GeneID:11188 -> Biological process: GO:0048243 [norepinephrine secretion] evidence: IEA
GeneID:11188 -> Cellular component: GO:0005769 [early endosome] evidence: IEA
GeneID:11188 -> Cellular component: GO:0005829 [cytosol] evidence: IDA
GeneID:11188 -> Cellular component: GO:0005886 [plasma membrane] evidence: IDA
GeneID:11188 -> Cellular component: GO:0055037 [recycling endosome] evidence: IEA
by
@meso_cacase at
DBCLS
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