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2024-04-26 13:46:17, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_006986 2760 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens melanoma antigen family D, 1 (MAGED1), transcript
variant 2, mRNA.
ACCESSION NM_006986
VERSION NM_006986.3 GI:52632376
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2760)
AUTHORS Zeng,Z.L., Wu,W.J., Yang,J., Tang,Z.J., Chen,D.L., Qiu,M.Z.,
Luo,H.Y., Wang,Z.Q., Jin,Y., Wang,D.S. and Xu,R.H.
TITLE Prognostic relevance of melanoma antigen D1 expression in
colorectal carcinoma
JOURNAL J Transl Med 10, 181 (2012)
PUBMED 22935435
REMARK GeneRIF: Univariate and multivariate analyses indicated that MAGED1
expression was an independent prognostic factor in colorectal
carcinoma
Publication Status: Online-Only
REFERENCE 2 (bases 1 to 2760)
AUTHORS Reddy,E.M., Chettiar,S.T., Kaur,N., Ganeshkumar,R., Shepal,V.,
Shanbhag,N.C. and Shiras,A.
TITLE Dlxin-1, a member of MAGE family, inhibits cell proliferation,
invasion and tumorigenicity of glioma stem cells
JOURNAL Cancer Gene Ther. 18 (3), 206-218 (2011)
PUBMED 21109781
REMARK GeneRIF: we establish the roles for Dlxin-1, one as an
anti-tumorigenic and anti-invasive protein in high-grade gliomas
and the other as an inducer of differentiation of glioma stem
cells.
REFERENCE 3 (bases 1 to 2760)
AUTHORS Xue,X.Y., Liu,Z.H., Jing,F.M., Li,Y.G., Liu,H.Z. and Gao,X.S.
TITLE Relationship between NRAGE and the radioresistance of esophageal
carcinoma cell line TE13R120
JOURNAL Chin J Cancer 29 (10), 900-906 (2010)
PUBMED 20868560
REMARK GeneRIF: NRAGE may participate in the formation of radioresistance
of TE13R120 cells by changing its subcellular localization, but its
relationship with cell apoptosis has not been confirmed.
REFERENCE 4 (bases 1 to 2760)
AUTHORS Davila,S., Froeling,F.E., Tan,A., Bonnard,C., Boland,G.J.,
Snippe,H., Hibberd,M.L. and Seielstad,M.
TITLE New genetic associations detected in a host response study to
hepatitis B vaccine
JOURNAL Genes Immun. 11 (3), 232-238 (2010)
PUBMED 20237496
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 5 (bases 1 to 2760)
AUTHORS Matluk,N., Rochira,J.A., Karaczyn,A., Adams,T. and Verdi,J.M.
TITLE A role for NRAGE in NF-kappaB activation through the non-canonical
BMP pathway
JOURNAL BMC Biol. 8, 7 (2010)
PUBMED 20100315
REMARK GeneRIF: Data report that NRAGE, via the same XIAP-Tak1-Tab1
complex, is required for the phosphorylation of IKK -alpha/beta and
subsequent transcriptional activation of the p65 subunit of
NF-kappaB.
Publication Status: Online-Only
REFERENCE 6 (bases 1 to 2760)
AUTHORS Masuda,Y., Sasaki,A., Shibuya,H., Ueno,N., Ikeda,K. and Watanabe,K.
TITLE Dlxin-1, a novel protein that binds Dlx5 and regulates its
transcriptional function
JOURNAL J. Biol. Chem. 276 (7), 5331-5338 (2001)
PUBMED 11084035
REFERENCE 7 (bases 1 to 2760)
AUTHORS Zhang,C.G., Xing,G.C., Wei,H.D., Yu,Y.T. and He,F.C.
TITLE [A new melanoma antigen-encoding gene subfamily in human chromosome
X]
JOURNAL Yi Chuan Xue Bao 28 (3), 197-203 (2001)
PUBMED 11280991
REFERENCE 8 (bases 1 to 2760)
AUTHORS Kubu,C.J., Goldhawk,D.G., Barker,P.A. and Verdi,J.M.
TITLE Identification of the translational initiation codon in human
MAGED1
JOURNAL Genomics 70 (1), 150-152 (2000)
PUBMED 11087672
REFERENCE 9 (bases 1 to 2760)
AUTHORS Salehi,A.H., Roux,P.P., Kubu,C.J., Zeindler,C., Bhakar,A.,
Tannis,L.L., Verdi,J.M. and Barker,P.A.
TITLE NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin
receptor and facilitates nerve growth factor-dependent apoptosis
JOURNAL Neuron 27 (2), 279-288 (2000)
PUBMED 10985348
REFERENCE 10 (bases 1 to 2760)
AUTHORS Pold,M., Zhou,J., Chen,G.L., Hall,J.M., Vescio,R.A. and
Berenson,J.R.
TITLE Identification of a new, unorthodox member of the MAGE gene family
JOURNAL Genomics 59 (2), 161-167 (1999)
PUBMED 10409427
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BX422007.2, CD387872.1,
BF529661.1, BC014070.2 and AF132205.1.
On Sep 24, 2004 this sequence version replaced gi:14195633.
Summary: This gene is a member of the melanoma antigen gene (MAGE)
family. Most of the genes of this family encode tumor specific
antigens that are not expressed in normal adult tissues except
testis. Although the protein encoded by this gene shares strong
homology with members of the MAGE family, it is expressed in almost
all normal adult tissues. This gene has been demonstrated to be
involved in the p75 neurotrophin receptor mediated programmed cell
death pathway. Three transcript variants encoding two different
isoforms have been found for this gene. [provided by RefSeq, Jul
2008].
Transcript Variant: This variant (2) lacks an alternate in-frame
coding exon compared to variant 1. The resulting isoform (b) has
the same N- and C-termini but is shorter compared to isoform a.
Variants 2 and 3 both encode isoform b.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AF258554.1, AF217963.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025082 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-16 BX422007.2 1-16
17-18 CD387872.1 1-2
19-38 BF529661.1 19-38
39-235 BC014070.2 2-198
236-2744 BC014070.2 367-2875
2745-2760 AF132205.1 1372-1387
FEATURES Location/Qualifiers
source 1..2760
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xp11.23"
gene 1..2760
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/note="melanoma antigen family D, 1"
/db_xref="GeneID:9500"
/db_xref="HGNC:6813"
/db_xref="HPRD:02202"
/db_xref="MIM:300224"
exon 1..154
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/inference="alignment:Splign:1.39.8"
variation 66..67
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="g"
/db_xref="dbSNP:11541163"
misc_feature 146..148
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/note="upstream in-frame stop codon"
exon 155..235
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/inference="alignment:Splign:1.39.8"
CDS 191..2527
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/note="isoform b is encoded by transcript variant 2;
neurotrophin receptor-interacting MAGE homolog;
melanoma-associated antigen D1; MAGE-D1 antigen; MAGE
tumor antigen CCF"
/codon_start=1
/product="melanoma-associated antigen D1 isoform b"
/protein_id="NP_008917.3"
/db_xref="GI:52632377"
/db_xref="CCDS:CCDS14337.1"
/db_xref="GeneID:9500"
/db_xref="HGNC:6813"
/db_xref="HPRD:02202"
/db_xref="MIM:300224"
/translation="
MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE
"
misc_feature 464..466
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphotyrosine; propagated from
UniProtKB/Swiss-Prot (Q9Y5V3.3); phosphorylation site"
misc_feature 464..466
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 464..466
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1076..1522
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9Y5V3.3);
Region: 22 X 6 AA tandem repeats of W-[PQ]-X-P-X-X"
misc_feature 1622..2131
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/note="MAGE family; Region: MAGE; pfam01454"
/db_xref="CDD:201804"
exon 236..943
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/inference="alignment:Splign:1.39.8"
variation 248
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:200403502"
variation 362
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:370800331"
variation 365
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:375273111"
variation 404
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:201938318"
variation 420
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:202085108"
variation 465
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:151112988"
variation 497
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:141080853"
variation 534
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:113823505"
variation 535
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:200269066"
variation 536
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="c"
/db_xref="dbSNP:137856838"
variation 634
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:144264968"
variation 656
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:200672367"
variation 665
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:373610127"
variation 694
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:183944548"
variation 852
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="g"
/db_xref="dbSNP:187608453"
variation 876
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:372248500"
variation 902
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="c"
/db_xref="dbSNP:12689461"
exon 944..1612
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/inference="alignment:Splign:1.39.8"
variation 1004
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:41307638"
variation 1011
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="c"
/db_xref="dbSNP:200760701"
variation 1057
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:140810987"
variation 1083
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:374985036"
variation 1103
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:144665907"
variation 1139
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="g"
/db_xref="dbSNP:369211587"
variation 1149
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:373153783"
variation 1252
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:138624949"
variation 1269
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:202231305"
variation 1360
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:141719497"
variation 1403
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="c"
/db_xref="dbSNP:199911189"
variation 1435
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:376126768"
variation 1441
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="c"
/db_xref="dbSNP:370215151"
variation 1480
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:184387756"
variation 1481
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:200856189"
variation 1517
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:377687584"
variation 1572
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:144566171"
variation 1583
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:148038224"
exon 1613..1676
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/inference="alignment:Splign:1.39.8"
exon 1677..1756
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/inference="alignment:Splign:1.39.8"
variation 1732
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:367685368"
exon 1757..1848
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/inference="alignment:Splign:1.39.8"
variation 1795
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:141770812"
variation 1822
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:150589159"
exon 1849..1928
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/inference="alignment:Splign:1.39.8"
variation 1879
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:371683752"
variation 1916
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:375975220"
exon 1929..1971
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/inference="alignment:Splign:1.39.8"
exon 1972..2034
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/inference="alignment:Splign:1.39.8"
variation 1985
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="g"
/db_xref="dbSNP:199703705"
exon 2035..2149
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/inference="alignment:Splign:1.39.8"
exon 2150..2535
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/inference="alignment:Splign:1.39.8"
variation 2182
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="t"
/db_xref="dbSNP:201229700"
variation 2188
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:140668837"
variation 2215
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:144656819"
variation 2242
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:368745871"
variation 2243
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:147478214"
variation 2249
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="c"
/db_xref="dbSNP:3199687"
variation 2416
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:200548781"
variation 2433
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="c"
/db_xref="dbSNP:150014410"
variation 2453
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:145319637"
variation 2485
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:149192593"
variation 2497
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:142436276"
variation 2526
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:145598419"
exon 2536..2744
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/inference="alignment:Splign:1.39.8"
variation 2550
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:58080956"
variation 2563
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="c"
/db_xref="dbSNP:193192478"
variation 2577
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:376570677"
variation 2595
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:1136500"
variation 2609
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="c"
/replace="t"
/db_xref="dbSNP:1136504"
variation 2624
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace="a"
/replace="g"
/db_xref="dbSNP:11541165"
variation 2690..2691
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
/replace=""
/replace="g"
/db_xref="dbSNP:35938097"
polyA_signal 2719..2724
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
polyA_site 2744
/gene="MAGED1"
/gene_synonym="DLXIN-1; NRAGE"
ORIGIN
ggcgaagaggcggggtcgcccaagctgccgcgctggcattttctcctggacaaggagagagtgcggctgctgagagccgagcccagcaatcccgatcctctgagtcgtgaagaagggaggcagcgagggggttggggttggggcctgaggcaagcccccaggctccgctcttgccagagggacaggagccatggctcagaaaatggactgtggtgcgggcctcctcggcttccaggctgaggcctccgtagaagacagcgccttgcttatgcagaccttgatggaggccatccagatctcagaggctccacctactaaccaggccaccgcagctgctagtccccagagttcacagcccccaactgccaatgagatggctgacattcaggtttcagcagctgccgctaggcctaagtcagcctttaaagtccagaatgccaccacaaaaggcccaaatggtgtctatgatttctctcaggctcataatgccaaggatgtgcccaacacgcagcccaaggcagcctttaagtcccaaaatgctaccccaaagggtccaaatgctgcctatgatttttcccaggcagcaaccactggtgagttagctgctaacaagtctgagatggccttcaaggcccagaatgccactactaaagtgggcccaaatgccacctacaatttctctcagtctctcaatgccaatgacctggccaacagcaggcctaagacccctttcaaggcttggaatgataccactaaggccccaacagctgatacccagacccagaatgtaaatcaggccaaaatggccacttcccaggctgacatagagaccgacccaggtatctctgaacctgacggtgcaactgcacagacatcagcagatggttcccaggctcagaatctggagtcccggacaataattcggggcaagaggacccgcaagattaataacttgaatgttgaagagaacagcagtggggatcagaggcgggccccactggctgcagggacctggaggtctgcaccagttccagtgaccactcagaacccacctggcgcaccccccaatgtgctctggcagacgccattggcttggcagaacccctcaggctggcaaaaccagacagccaggcagaccccaccagcacgtcagagccctccagctaggcagaccccaccagcctggcagaacccagtcgcttggcagaacccagtgatttggccaaacccagtaatctggcagaacccagtgatctggccaaaccccattgtctggcccggccctgttgtctggccgaatccactggcctggcagaatccacctggatggcagactccacctggatggcagaccccaccgggctggcagggtcctccagactggcaaggtcctcctgactggccgctaccacccgactggccactgccacctgattggccacttcccactgactggccactaccacctgactggatccccgctgattggccaattccacctgactggcagaacctgcgcccctcgcctaacctgcgcccttctcccaactcgcgtgcctcacagaacccaggtgctgcacagccccgagatgtggcccttcttcaggaaagagcaaataagttggtcaagtacttgatgcttaaggactacacaaaggtgcccatcaagcgctcagaaatgctgagagatatcatccgtgaatacactgatgtttatccagaaatcattgaacgtgcatgctttgtcctagagaagaaatttgggattcaactgaaagaaattgacaaagaagaacacctgtatattctcatcagtacccccgagtccctggctggcatactgggaacgaccaaagacacacccaagctcggtctcctcttggtgattctgggtgtcatcttcatgaatggcaaccgtgccagtgaggctgtcctctgggaggcactacgcaagatgggactgcgtcctggggtgagacatcccctccttggagatctaaggaaacttctcacctatgagtttgtaaagcagaaatacctggactacagacgagtgcccaacagcaaccccccggagtatgagttcctctggggcctccgttcctaccatgagactagcaagatgaaagtgctgagattcattgcagaggttcagaaaagagaccctcgtgactggactgcacagttcatggaggctgcagatgaggccttggatgctctggatgctgctgcagctgaggccgaagcccgggctgaagcaagaacccgcatgggaattggagatgaggctgtgtctgggccctggagctgggatgacattgagtttgagctgctgacctgggatgaggaaggagattttggagatccctggtccagaattccatttaccttctgggccagataccaccagaatgcccgctccagattccctcagacctttgccggtcccattattggtcctggtggtacagccagtgccaacttcgctgccaactttggtgccattggtttcttctgggttgagtgagatgttggatattgctatcaatcgcagtagtctttcccctgtgtgaggctgaagcctcagattccttctaaacacagctatctagagagccacatcctgttgactgaaagtggcatgcaagataaatttatttgctgttccttgtctactgctttttttccccttgtgtgctgtcaagttttggtatcagaaataaacattgaaattgcaaagtgaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:9500 -> Molecular function: GO:0003713 [transcription coactivator activity] evidence: IEA
GeneID:9500 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:9500 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: TAS
GeneID:9500 -> Biological process: GO:0006357 [regulation of transcription from RNA polymerase II promoter] evidence: IEA
GeneID:9500 -> Biological process: GO:0006915 [apoptotic process] evidence: TAS
GeneID:9500 -> Biological process: GO:0042981 [regulation of apoptotic process] evidence: TAS
GeneID:9500 -> Biological process: GO:0043065 [positive regulation of apoptotic process] evidence: TAS
GeneID:9500 -> Biological process: GO:0043406 [positive regulation of MAP kinase activity] evidence: IEA
GeneID:9500 -> Biological process: GO:0045892 [negative regulation of transcription, DNA-dependent] evidence: IEA
GeneID:9500 -> Biological process: GO:0045893 [positive regulation of transcription, DNA-dependent] evidence: IEA
GeneID:9500 -> Biological process: GO:0048011 [neurotrophin TRK receptor signaling pathway] evidence: TAS
GeneID:9500 -> Biological process: GO:0050680 [negative regulation of epithelial cell proliferation] evidence: IDA
GeneID:9500 -> Biological process: GO:0090190 [positive regulation of branching involved in ureteric bud morphogenesis] evidence: IEA
GeneID:9500 -> Biological process: GO:0097190 [apoptotic signaling pathway] evidence: TAS
GeneID:9500 -> Cellular component: GO:0005737 [cytoplasm] evidence: IEA
GeneID:9500 -> Cellular component: GO:0005886 [plasma membrane] evidence: IEA
GeneID:9500 -> Cellular component: GO:0043234 [protein complex] evidence: IDA
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DBCLS
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