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2024-04-19 08:15:50, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_006888               4268 bp    mRNA    linear   PRI 24-JUN-2013
DEFINITION  Homo sapiens calmodulin 1 (phosphorylase kinase, delta) (CALM1),
            mRNA.
ACCESSION   NM_006888
VERSION     NM_006888.4  GI:260656023
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4268)
  AUTHORS   Farrer,R.G., Farrer,J.R. and DeVries,G.H.
  TITLE     Platelet-derived growth factor-BB activates
            calcium/calmodulin-dependent and -independent mechanisms that
            mediate Akt phosphorylation in the neurofibromin-deficient human
            Schwann cell line ST88-14
  JOURNAL   J. Biol. Chem. 288 (16), 11066-11073 (2013)
   PUBMED   23457304
  REMARK    GeneRIF: the activation of the calcium/CaM/Akt pathway resulting
            from stimulation of overexpressed PDGF receptor-beta may contribute
            to the survival and tumorigenicity of MPNST cells.
REFERENCE   2  (bases 1 to 4268)
  AUTHORS   Crotti,L., Johnson,C.N., Graf,E., De Ferrari,G.M., Cuneo,B.F.,
            Ovadia,M., Papagiannis,J., Feldkamp,M.D., Rathi,S.G., Kunic,J.D.,
            Pedrazzini,M., Wieland,T., Lichtner,P., Beckmann,B.M., Clark,T.,
            Shaffer,C., Benson,D.W., Kaab,S., Meitinger,T., Strom,T.M.,
            Chazin,W.J., Schwartz,P.J. and George,A.L. Jr.
  TITLE     Calmodulin mutations associated with recurrent cardiac arrest in
            infants
  JOURNAL   Circulation 127 (9), 1009-1017 (2013)
   PUBMED   23388215
  REMARK    GeneRIF: Defects in calmodulin function disrupt calcium signaling
            events in heart and result in deadly disturbances in heart rhythm
            during infancy.
REFERENCE   3  (bases 1 to 4268)
  AUTHORS   Wang,H., Gao,X., Yang,J.J. and Liu,Z.R.
  TITLE     Interaction between p68 RNA helicase and Ca2+-calmodulin promotes
            cell migration and metastasis
  JOURNAL   Nat Commun 4, 1354 (2013)
   PUBMED   23322042
  REMARK    GeneRIF: p68, in the presence of Ca-calmodulin, can function as a
            microtubule motor.
REFERENCE   4  (bases 1 to 4268)
  AUTHORS   Rebas,E., Boczek,T., Kowalski,A., Kusmirowska,K., Lisek,M. and
            Zylinska,L.
  TITLE     [The role of calmodulin in calcium-dependent signalling in
            excitable cells]
  JOURNAL   Postepy Biochem. 58 (4), 393-402 (2012)
   PUBMED   23662433
  REMARK    GeneRIF: In this review, calmodulin (CaM) is discussed as a sensor
            protein, which takes part in calcium-dependent signaling,
            regulating processes like growth, differentiation, proliferation
            and motility.
            Review article
REFERENCE   5  (bases 1 to 4268)
  AUTHORS   Rhyner,J.A., Ottiger,M., Wicki,R., Greenwood,T.M. and Strehler,E.E.
  TITLE     Structure of the human CALM1 calmodulin gene and identification of
            two CALM1-related pseudogenes CALM1P1 and CALM1P2
  JOURNAL   Eur. J. Biochem. 225 (1), 71-82 (1994)
   PUBMED   7925473
REFERENCE   6  (bases 1 to 4268)
  AUTHORS   Kessler,F., Falchetto,R., Heim,R., Meili,R., Vorherr,T.,
            Strehler,E.E. and Carafoli,E.
  TITLE     Study of calmodulin binding to the alternatively spliced C-terminal
            domain of the plasma membrane Ca2+ pump
  JOURNAL   Biochemistry 31 (47), 11785-11792 (1992)
   PUBMED   1332771
REFERENCE   7  (bases 1 to 4268)
  AUTHORS   Sacks,D.B., Davis,H.W., Crimmins,D.L. and McDonald,J.M.
  TITLE     Insulin-stimulated phosphorylation of calmodulin
  JOURNAL   Biochem. J. 286 (PT 1), 211-216 (1992)
   PUBMED   1520270
REFERENCE   8  (bases 1 to 4268)
  AUTHORS   de Lillo,A., Tejerina,J.M. and Fierro,J.F.
  TITLE     Interaction of calmodulin with lactoferrin
  JOURNAL   FEBS Lett. 298 (2-3), 195-198 (1992)
   PUBMED   1544444
REFERENCE   9  (bases 1 to 4268)
  AUTHORS   Koller,M., Schnyder,B. and Strehler,E.E.
  TITLE     Structural organization of the human CaMIII calmodulin gene
  JOURNAL   Biochim. Biophys. Acta 1087 (2), 180-189 (1990)
   PUBMED   2223880
REFERENCE   10 (bases 1 to 4268)
  AUTHORS   SenGupta,B., Friedberg,F. and Detera-Wadleigh,S.D.
  TITLE     Molecular analysis of human and rat calmodulin complementary DNA
            clones. Evidence for additional active genes in these species
  JOURNAL   J. Biol. Chem. 262 (34), 16663-16670 (1987)
   PUBMED   2445749
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL512791.3, AU122722.1,
            BC011834.2 and AI651063.1.
            This sequence is a reference standard in the RefSeqGene project.
            On Oct 7, 2009 this sequence version replaced gi:87196336.
            
            Summary: This gene encodes a member of the EF-hand calcium-binding
            protein family. It is one of three genes which encode an identical
            calcium binding protein which is one of the four subunits of
            phosphorylase kinase. Two pseudogenes have been identified on
            chromosome 7 and X. Multiple transcript variants encoding different
            isoforms have been found for this gene.[provided by RefSeq, Oct
            2009].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC047523.1, BX339621.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025082 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-46                AL512791.3         64066-64111
            47-165              AU122722.1         1-119
            166-1566            BC011834.2         120-1520
            1567-4235           AL512791.3         72669-75337
            4236-4268           AI651063.1         1-33                c
FEATURES             Location/Qualifiers
     source          1..4268
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q32.11"
     gene            1..4268
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /note="calmodulin 1 (phosphorylase kinase, delta)"
                     /db_xref="GeneID:801"
                     /db_xref="HGNC:1442"
                     /db_xref="HPRD:00241"
                     /db_xref="MIM:114180"
     exon            1..251
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /inference="alignment:Splign:1.39.8"
     variation       31
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:12885713"
     variation       45
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:184206045"
     variation       46
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:111249181"
     variation       76
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188359112"
     variation       81
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146545930"
     variation       85
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:181001910"
     variation       88
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141007341"
     variation       97
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:12886186"
     misc_feature    141..143
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /note="upstream in-frame stop codon"
     variation       158..163
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace=""
                     /replace="gcagcg"
                     /db_xref="dbSNP:200148015"
     variation       163
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:12886342"
     variation       217
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:12886083"
     variation       227
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369555148"
     variation       232
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372252650"
     CDS             249..698
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /EC_number="2.7.11.19"
                     /note="phosphorylase kinase, delta subunit;
                     prepro-calmodulin 1"
                     /codon_start=1
                     /product="calmodulin"
                     /protein_id="NP_008819.1"
                     /db_xref="GI:5901912"
                     /db_xref="CCDS:CCDS9892.1"
                     /db_xref="GeneID:801"
                     /db_xref="HGNC:1442"
                     /db_xref="HPRD:00241"
                     /db_xref="MIM:114180"
                     /translation="
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
"
     misc_feature    249..695
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /note="calmodulin; Provisional; Region: PTZ00184"
                     /db_xref="CDD:185504"
     misc_feature    252..254
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N-acetylalanine; propagated from
                     UniProtKB/Swiss-Prot (P62158.2); acetylation site"
     misc_feature    282..470
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /note="EF-hand, calcium binding motif; A diverse
                     superfamily of calcium sensors and calcium signal
                     modulators; most examples in this alignment model have 2
                     active canonical EF hands. Ca2+ binding induces a
                     conformational change in the EF-hand motif, leading to...;
                     Region: EFh; cd00051"
                     /db_xref="CDD:238008"
     misc_feature    order(309..311,315..317,321..323,342..344,417..419,
                     423..425,429..431,450..452)
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238008"
     misc_feature    312..314
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N6-acetyllysine, alternate; propagated from
                     UniProtKB/Swiss-Prot (P62158.2); acetylation site"
     misc_feature    501..689
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /note="EF-hand, calcium binding motif; A diverse
                     superfamily of calcium sensors and calcium signal
                     modulators; most examples in this alignment model have 2
                     active canonical EF hands. Ca2+ binding induces a
                     conformational change in the EF-hand motif, leading to...;
                     Region: EFh; cd00051"
                     /db_xref="CDD:238008"
     misc_feature    order(528..530,534..536,540..542,561..563,636..638,
                     642..644,648..650,669..671)
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238008"
     misc_feature    531..533
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N6-acetyllysine; propagated from
                     UniProtKB/Swiss-Prot (P62158.2); acetylation site"
     misc_feature    546..548
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphotyrosine; propagated from
                     UniProtKB/Swiss-Prot (P62158.2); phosphorylation site"
     misc_feature    546..548
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /db_xref="HPRD:00579"
     misc_feature    546..548
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /db_xref="HPRD:00975"
     misc_feature    552..554
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P62158.2); phosphorylation site"
     misc_feature    594..596
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N6,N6,N6-trimethyllysine; propagated from
                     UniProtKB/Swiss-Prot (P62158.2); methylation site"
     misc_feature    594..596
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="methylation site"
     misc_feature    663..665
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphotyrosine; propagated from
                     UniProtKB/Swiss-Prot (P62158.2); phosphorylation site"
     misc_feature    663..665
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /db_xref="HPRD:00975"
     exon            252..282
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /inference="alignment:Splign:1.39.8"
     variation       277
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373571763"
     exon            283..426
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /inference="alignment:Splign:1.39.8"
     variation       317
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144339242"
     variation       320
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:267607278"
     variation       367
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199950662"
     variation       373
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:199897752"
     variation       397
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202194260"
     variation       409
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:267607276"
     exon            427..533
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /inference="alignment:Splign:1.39.8"
     STS             441..597
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="GDB:433805"
                     /db_xref="UniSTS:157197"
     variation       491
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200250055"
     variation       520
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11541171"
     exon            534..669
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /inference="alignment:Splign:1.39.8"
     variation       541
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:267607277"
     variation       551
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143503733"
     variation       572
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139706811"
     variation       614
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370441016"
     variation       650
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:193072150"
     variation       665
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377521523"
     exon            670..4256
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /inference="alignment:Splign:1.39.8"
     variation       674
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199744595"
     variation       675
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:370956572"
     variation       709
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201339726"
     variation       716
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200742588"
     STS             721..1545
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="Calm1"
                     /db_xref="UniSTS:506762"
     variation       722
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372713000"
     variation       855
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111354847"
     variation       975
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183167213"
     variation       981
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:367695382"
     variation       1026
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371446473"
     STS             1031..1192
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="G54145"
                     /db_xref="UniSTS:109382"
     variation       1115
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:5871"
     STS             1173..1315
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="WI-18834"
                     /db_xref="UniSTS:36651"
     variation       1219
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:112958092"
     variation       1319
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:187714594"
     variation       1434
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1059285"
     variation       1472..1473
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace=""
                     /replace="gg"
                     /db_xref="dbSNP:139060064"
     STS             1474..1733
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="RH70561"
                     /db_xref="UniSTS:72957"
     variation       1477
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199697317"
     variation       1551..1552
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:35149335"
     variation       1551
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370254226"
     variation       1552..1553
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:71823341"
     variation       1557
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:71771679"
     variation       1566..1567
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace=""
                     /replace="t"
                     /replace="ttt"
                     /db_xref="dbSNP:56856377"
     variation       1567
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:111860684"
     STS             1595..1834
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="D14S98E"
                     /db_xref="UniSTS:58767"
     STS             1714..1791
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="D14S98E"
                     /db_xref="UniSTS:147484"
     STS             1722..1871
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="SHGC-30527"
                     /db_xref="UniSTS:33778"
     variation       1735
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:11541170"
     variation       1736
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:116646015"
     variation       1780
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1059296"
     variation       1836..1837
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace=""
                     /replace="tt"
                     /db_xref="dbSNP:374013990"
     variation       1842
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373356188"
     variation       1870
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61989066"
     variation       1872..1873
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace=""
                     /replace="aa"
                     /db_xref="dbSNP:80212837"
     variation       1872
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:11287138"
     variation       1872
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:63576962"
     variation       1873
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:77928599"
     variation       1882
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:77916091"
     variation       1885
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:78459823"
     variation       1895
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:146008731"
     variation       1980
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:115723958"
     variation       1992..1993
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace=""
                     /replace="tg"
                     /db_xref="dbSNP:202213644"
     variation       2001
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376504500"
     variation       2002
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:138659409"
     variation       2048
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:75951656"
     variation       2068
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:192521929"
     variation       2088
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183678923"
     variation       2089
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369307361"
     variation       2116..2118
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace=""
                     /replace="cct"
                     /db_xref="dbSNP:67661612"
     variation       2118
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:3814846"
     variation       2125..2126
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace=""
                     /replace="cc"
                     /db_xref="dbSNP:71461906"
     variation       2125
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61989067"
     variation       2127..2128
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:200711428"
     variation       2127
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:71461907"
     variation       2128
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:75202062"
     variation       2142
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:3814845"
     STS             2173..2266
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="D14S89E"
                     /db_xref="UniSTS:147526"
     variation       2175
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373565285"
     STS             2177..2281
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="D14S642E"
                     /db_xref="UniSTS:11318"
     STS             2242..2434
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="D14S89E"
                     /db_xref="UniSTS:17090"
     STS             2272..2372
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="1928"
                     /db_xref="UniSTS:47094"
     STS             2279..2387
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="D14S1231"
                     /db_xref="UniSTS:69176"
     variation       2332
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375596643"
     variation       2380
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141870617"
     variation       2396
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3814844"
     STS             2400..2499
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="D14S89E"
                     /db_xref="UniSTS:147442"
     variation       2537
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:369706187"
     variation       2540
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186848664"
     variation       2568
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35418035"
     variation       2647
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374437556"
     variation       2650
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:3814843"
     variation       2662
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:139692985"
     variation       2714
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:192452102"
     variation       2783
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184803743"
     variation       2824
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149760583"
     variation       2834
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370139244"
     variation       2861..2862
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace=""
                     /replace="ca"
                     /db_xref="dbSNP:374154318"
     variation       2901
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:189778902"
     variation       2909
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:181805019"
     variation       2916
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:184371119"
     variation       2937
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367855711"
     variation       2948
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:189147924"
     variation       2949
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:181955035"
     variation       3049
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:3179089"
     variation       3351
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:184950622"
     variation       3363..3369
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace=""
                     /replace="ataagaa"
                     /db_xref="dbSNP:200991845"
     variation       3410
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:11539544"
     variation       3435
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1058903"
     variation       3548
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367644606"
     variation       3556..3559
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace=""
                     /replace="acac"
                     /db_xref="dbSNP:150072386"
     variation       3645
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:140025082"
     variation       3678
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:115172487"
     STS             3770..3977
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="G06214"
                     /db_xref="UniSTS:24581"
     variation       3786
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145426711"
     STS             3828..3977
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="RH11243"
                     /db_xref="UniSTS:24582"
     STS             3831..3932
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="D14S901"
                     /db_xref="UniSTS:42830"
     variation       3916
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147728175"
     STS             3943..4153
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="EST13B3"
                     /db_xref="UniSTS:263093"
     STS             3958..4088
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="RH11167"
                     /db_xref="UniSTS:77599"
     STS             3962..4165
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="SSC3C06"
                     /db_xref="UniSTS:253869"
     variation       3965
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370549807"
     variation       3975
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:142500788"
     variation       3981
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144946670"
     variation       4006
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:371784290"
     polyA_signal    4015..4020
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
     polyA_site      4035
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
     STS             4072..4237
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="IB3608"
                     /db_xref="UniSTS:53368"
     variation       4087
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:190976650"
     STS             4089..4239
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /standard_name="RH130082"
                     /db_xref="UniSTS:213370"
     variation       4090..4091
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:200917629"
     variation       4161
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:15414"
     polyA_signal    4219..4224
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
     polyA_site      4256
                     /gene="CALM1"
                     /gene_synonym="CALML2; caM; CAMI; CPVT4; DD132; PHKD"
ORIGIN      
gatacggcgcaccatatatatatcgcggggcgcagactcgcgctccggcagtggtgctgggagtgtcgtggacgccgtgccgttactcgtagtcaggcggcggcgcaggcggcggcggcggcatagcgcacagcgcgccttagcagcagcagcagcagcagcggcatcggaggtacccccgccgtcgcagcccccgcgctggtgcagccaccctcgctccctctgctcttcctcccttcgctcgcaccatggctgatcagctgaccgaagaacagattgctgaattcaaggaagccttctccctatttgataaagatggcgatggcaccatcacaacaaaggaacttggaactgtcatgaggtcactgggtcagaacccaacagaagctgaattgcaggatatgatcaatgaagtggatgctgatggtaatggcaccattgacttccccgaatttttgactatgatggctagaaaaatgaaagatacagatagtgaagaagaaatccgtgaggcattccgagtctttgacaaggatggcaatggttatatcagtgcagcagaactacgtcacgtcatgacaaacttaggagaaaaactaacagatgaagaagtagatgaaatgatcagagaagcagatattgatggagacggacaagtcaactatgaagaattcgtacagatgatgactgcaaaatgaagacctactttcaactcctttttcccccctctagaagaatcaaattgaatcttttacttacctcttgcaaaaaaaagaaaaaagaaaaaagttcatttattcattctgtttctatatagcaaaactgaatgtcaaaagtaccttctgtccacacacacaaaatctgcatgtattggttggtggtcctgtcccctaaagatcaagctacacatcagttttacaatataaatacttgtactaccttaatgataaggactccttaaagttccatttgctaatgattaatacactgtttgggctggccagtttttcatgcatgcagcttgacgattgagcacagtcaggcctttgtattaaaaatgaaaaatgaaaaaacaaattcaaaacctattcaaatgggttctagttcaatttgtttagtataaattgtcatagctggtttactgaaaacaaacacatttaaaattggtttacctcaggatgacgtgcagaaaaatgggtgaaggataaaccgttgagacgtggccccactggtaggatggtcctcttgtacttcgtgtgctccgacccatggtgacgatgacacaccctggtggcatgcccgtgtatgttggtttagcgttgtctgcattgttctagagtgaaacaggtgtcaggctgtcactgttcacacaaatttttaataagaaacatttaccaagggagcatctttggactctctgtttttaaaaccttctgaaccatgacttggagccggcagagtaggctgtggctgtggacttcagcacaaccatcaacattgctgttcaaagaaattacagtttacgtccattccaagttgtaaatgctagtctttttttttttttttccaataaaaagaccattaacttaaagtggtgttaaatgctttgtaaagctgagatctaaatggggacaaggcaggtggaggggaggccagtgtacatgtaaatgcccacagcccagcattgggtttccctcccaaggccccagcaccaacctctgagcccaagaccttgcctgaaaacaagcagataccgattgcttcatcctatttatggacatgtaggtctagttgcattttcactggggggaggggggaaggtgaattatggtaacttttaatgatctattcaggcagtagagctcttaaggaaaaaaaaaaacccactttctctcaagcatgtatttaggggttgttctcaattgtgctgctgattacctgtcttatgtaactacttgagaccatctgcaagagacatgatttagtgtgtctgtaattcaatcttcgctgtgtgtggtagaagcagtagtcacttttgtaagccagtctcttcatgcctaaaagacactaccagtcacctttgattcgcgacttttaatttatgattatacttagcctcctcctcctttttttttttttcccaagttgacttgactttgcttttttccccccaagtagaactaatgctagcttccagcttgaaagtaaaactccagtgtggagtgaattttgtgtctaattataaacctgtaaccaaaactcagacatctggtactggtctttgcattgagattggtccctgtaaaaccccctttaaaagcatattgcatttagtacagagctcttttttgaaatgaaggctggagatgtgcatttttcacggtgttaactggttgtatcttattagcaaggagattggggttttgagtgtttgcgtgggtggtttcaatttgccagggaacagtggcaggctgctagcaaggcagtgagaagctcttggcagccaaatgggtgcattcagggctgatttatagagacccttggcttctccttctcctactccctgtctttctggcattttgtagcttgttagattttctgccagaggggtgggtcagagcagtggaggggagacatcgcccatgtgcttctgctactggtccttgggctgggtggttggtagaggagatgttgacactatgagctaagggttggcttttgtaattacctgaatctgaaaggaatgcctaaggttaccttggggtttctcttctggtgagatagggttcctggtttgagtaagttaatgtcctggatatttcttgtggcagggggtggtcaaagagcctgattgctgacccagtctcaggcctgtggtcgatgacctctcggtagtttcaaagggggctggagggggatatttgacttgttttttcgaaatgtagccttctaaccctcaagtctttagaagctgggtggactcttagtggtcctgcagcgtatcctaaaagactacctttgaaacaggattcttgtatggccaggatcctgtctgggaaccagaaaccctacaccctccccctccagggaatgctgagttccagttttgagcagaggtgaggcagaatccactgtagccttccgccctggtatttggggggatgaccagcccaggcgttgggtgttagtctgcatgagtttgtgagaggaaatagctgggtgtcctggcagtgcccttgaagttggttaggaccttcctgtaaactcttgcccctacttctaactactctataaatatatacatatatttatatataaagtgattagttgaactggcatcctgctttagcctgagacttgccataagaaactgctgagtacttggcaaaccctttcatagttttgttctccatctgtttggggtaggtgttgagcgaggcaaatggatctcgatatttcagatgggcttttgatgcactgttgccaaggaaggctttttctgattttttgacaaatgaatttttgcacactttcattggtgtctttcggcaacttacacacattgaaaatgagctattgtacatatttttatattctctttataaatgcatgtctgattgtacttgtaacaatattgtaatgaacggctgtgcagtaggcccagcgctgctgtgtctcgtcagaggaatagcttaccacgaacccctcagcatactgggaatctcttcctgaacaacgaatgtaaatttggtcaagtctactcttccgttcattcaattattttaagcatttgaattatttattgtatatcctaaatatatttctcctttggcagtgactagatttccactaatgtgtcttaatctatccctccagctggcagttactgtttttttaatcccctgaagttgtcctgtaggagacagaaattctttgctgtctgtatcccttggagtaagaaggtagtggcatgggtggagtgtgtgttctttctccaaatctattatgatgtttattaaacacttctgtagcaaagatggtggtagttcttttgttactgaagttgcccttcaccatggctatttgaaaaggagatgtacttggacgtttctgtaaatcttgagataaactgtttggagatttaaccacctctctgatgggggaccaactctatggaaattgtaaatacgttttatttataaacctggcactgtattcaataaacatttctgcagcctttcatctctaactgcgaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            NP_008819 -> EC 2.7.11.19

by @meso_cacase at DBCLS
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