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2024-04-18 13:10:35, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_006633 5769 bp mRNA linear PRI 15-JUN-2013
DEFINITION Homo sapiens IQ motif containing GTPase activating protein 2
(IQGAP2), mRNA.
ACCESSION NM_006633
VERSION NM_006633.2 GI:116089336
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5769)
AUTHORS Del-Aguila,J.L., Beitelshees,A.L., Cooper-Dehoff,R.M.,
Chapman,A.B., Gums,J.G., Bailey,K., Gong,Y., Turner,S.T.,
Johnson,J.A. and Boerwinkle,E.
TITLE Genome-wide association analyses suggest NELL1 influences adverse
metabolic response to HCTZ in African Americans
JOURNAL Pharmacogenomics J. (2013) In press
PUBMED 23400010
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 5769)
AUTHORS Xie,Y., Yan,J., Cutz,J.C., Rybak,A.P., He,L., Wei,F., Kapoor,A.,
Schmidt,V.A., Tao,L. and Tang,D.
TITLE IQGAP2, A candidate tumour suppressor of prostate tumorigenesis
JOURNAL Biochim. Biophys. Acta 1822 (6), 875-884 (2012)
PUBMED 22406297
REMARK GeneRIF: observations strongly indicate that IQGAP2 is a
surveillance type of tumour suppressor for prostate cancer
REFERENCE 3 (bases 1 to 5769)
AUTHORS Flachsbart,F., Franke,A., Kleindorp,R., Caliebe,A., Blanche,H.,
Schreiber,S. and Nebel,A.
TITLE Investigation of genetic susceptibility factors for human longevity
- a targeted nonsynonymous SNP study
JOURNAL Mutat. Res. 694 (1-2), 13-19 (2010)
PUBMED 20800603
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 4 (bases 1 to 5769)
AUTHORS Bailey,S.D., Xie,C., Do,R., Montpetit,A., Diaz,R., Mohan,V.,
Keavney,B., Yusuf,S., Gerstein,H.C., Engert,J.C. and Anand,S.
CONSRTM DREAM investigators
TITLE Variation at the NFATC2 locus increases the risk of
thiazolidinedione-induced edema in the Diabetes REduction
Assessment with ramipril and rosiglitazone Medication (DREAM) study
JOURNAL Diabetes Care 33 (10), 2250-2253 (2010)
PUBMED 20628086
REMARK GeneRIF: Observational study of gene-disease association,
gene-environment interaction, and pharmacogenomic / toxicogenomic.
(HuGE Navigator)
REFERENCE 5 (bases 1 to 5769)
AUTHORS White,C.D., Khurana,H., Gnatenko,D.V., Li,Z., Odze,R.D., Sacks,D.B.
and Schmidt,V.A.
TITLE IQGAP1 and IQGAP2 are reciprocally altered in hepatocellular
carcinoma
JOURNAL BMC Gastroenterol 10, 125 (2010)
PUBMED 20977743
REMARK GeneRIF: increased IQGAP1 and/or decreased IQGAP2 contribute to the
pathogenesis of human HCC.
Publication Status: Online-Only
REFERENCE 6 (bases 1 to 5769)
AUTHORS Gevaert,K., Goethals,M., Martens,L., Van Damme,J., Staes,A.,
Thomas,G.R. and Vandekerckhove,J.
TITLE Exploring proteomes and analyzing protein processing by mass
spectrometric identification of sorted N-terminal peptides
JOURNAL Nat. Biotechnol. 21 (5), 566-569 (2003)
PUBMED 12665801
REFERENCE 7 (bases 1 to 5769)
AUTHORS Schmidt,V.A., Scudder,L., Devoe,C.E., Bernards,A., Cupit,L.D. and
Bahou,W.F.
TITLE IQGAP2 functions as a GTP-dependent effector protein in
thrombin-induced platelet cytoskeletal reorganization
JOURNAL Blood 101 (8), 3021-3028 (2003)
PUBMED 12515716
REMARK GeneRIF: The gene for the putative rac1/cdc42 effector protein
IQGAP2 was found in the PAR gene cluster at 5q13, flanked by PAR1 &
encompassing PAR3. It functions as a GTP-dependent effector protein
in thrombin-induced platelet cytoskeletal reorganization.
REFERENCE 8 (bases 1 to 5769)
AUTHORS Wennerberg,K., Ellerbroek,S.M., Liu,R.Y., Karnoub,A.E., Burridge,K.
and Der,C.J.
TITLE RhoG signals in parallel with Rac1 and Cdc42
JOURNAL J. Biol. Chem. 277 (49), 47810-47817 (2002)
PUBMED 12376551
REFERENCE 9 (bases 1 to 5769)
AUTHORS McCallum,S.J., Wu,W.J. and Cerione,R.A.
TITLE Identification of a putative effector for Cdc42Hs with high
sequence similarity to the RasGAP-related protein IQGAP1 and a
Cdc42Hs binding partner with similarity to IQGAP2
JOURNAL J. Biol. Chem. 271 (36), 21732-21737 (1996)
PUBMED 8702968
REFERENCE 10 (bases 1 to 5769)
AUTHORS Brill,S., Li,S., Lyman,C.W., Church,D.M., Wasmuth,J.J.,
Weissbach,L., Bernards,A. and Snijders,A.J.
TITLE The Ras GTPase-activating-protein-related human protein IQGAP2
harbors a potential actin binding domain and interacts with
calmodulin and Rho family GTPases
JOURNAL Mol. Cell. Biol. 16 (9), 4869-4878 (1996)
PUBMED 8756646
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
U51903.1, DB075371.1, AB208856.1 and BI481276.1.
On Oct 13, 2006 this sequence version replaced gi:5729886.
Summary: This gene encodes a member of the IQGAP family. The
protein contains three IQ domains, one calponin homology domain,
one Ras-GAP domain and one WW domain. It interacts with components
of the cytoskeleton, with cell adhesion molecules, and with several
signaling molecules to regulate cell morphology and motility.
[provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: U51903.1, AK291066.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025084, ERS025088 [ECO:0000348]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-1802 U51903.1 1-1802
1803-1815 DB075371.1 299-311
1816-2108 U51903.1 1816-2108
2109-2765 AB208856.1 627-1283
2766-5065 U51903.1 2766-5065
5066-5764 AB208856.1 3584-4282
5765-5767 U51903.1 5765-5767
5768-5769 BI481276.1 283-284
FEATURES Location/Qualifiers
source 1..5769
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q13.3"
gene 1..5769
/gene="IQGAP2"
/note="IQ motif containing GTPase activating protein 2"
/db_xref="GeneID:10788"
/db_xref="HGNC:6111"
/db_xref="MIM:605401"
exon 1..268
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 11
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:116588852"
variation 14
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:371320955"
variation 46
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:1122654"
misc_feature 103..105
/gene="IQGAP2"
/note="upstream in-frame stop codon"
variation 103
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:112531987"
variation 204
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:368092917"
CDS 223..4950
/gene="IQGAP2"
/codon_start=1
/product="ras GTPase-activating-like protein IQGAP2"
/protein_id="NP_006624.2"
/db_xref="GI:116089337"
/db_xref="CCDS:CCDS34188.1"
/db_xref="GeneID:10788"
/db_xref="HGNC:6111"
/db_xref="MIM:605401"
/translation="
MPHEELPSLQRPRYGSIVDDERLSAEEMDERRRQNIAYEYLCHLEEAKRWMEVCLVEELPPTTELEEGLRNGVYLAKLAKFFAPKMVSEKKIYDVEQTRYKKSGLHFRHTDNTVQWLRAMESIGLPKIFYPETTDVYDRKNIPRMIYCIHALSLYLFKLGIAPQIQDLLGKVDFTEEEISNMRKELEKYGIQMPSFSKIGGILANELSVDEAALHAAVIAINEAVEKGIAEQTVVTLRNPNAVLTLVDDNLAPEYQKELWDAKKKKEENARLKNSCISEEERDAYEELLTQAEIQGNINKVNRQAAVDHINAVIPEGDPENTLLALKKPEAQLPAVYPFAAAMYQNELFNLQKQNTMNYLAHEELLIAVEMLSAVALLNQALESNDLVSVQNQLRSPAIGLNNLDKAYVERYANTLLSVKLEVLSQGQDNLSWNEIQNCIDMVNAQIQEENDRVVAVGYINEAIDEGNPLRTLETLLLPTANISDVDPAHAQHYQDVLYHAKSQKLGDSESVSKVLWLDEIQQAVDDANVDEDRAKQWVTLVVDVNQCLEGKKSSDILSVLKSSTSNANDIIPECADKYYDALVKAKELKSERVSSDGSWLKLNLHKKYDYYYNTDSKESSWVTPESCLYKESWLTGKEIEDIIEEVTVGYIRENIWSASEELLLRFQATSSGPILREEFEARKSFLHEQEENVVKIQAFWKGYKQRKEYMHRRQTFIDNTDSIVKIQSWFRMATARKSYLSRLQYFRDHNNEIVKIQSLLRANKARDDYKTLVGSENPPLTVIRKFVYLLDQSDLDFQEELEVARLREEVVTKIRANQQLEKDLNLMDIKIGLLVKNRITLEDVISHSKKLNKKKGGEMEILNNTDNQGIKSLSKERRKTLETYQQLFYLLQTNPLYLAKLIFQMPQNKSTKFMDTVIFTLYNYASNQREEYLLLKLFKTALEEEIKSKVDQVQDIVTGNPTVIKMVVSFNRGARGQNTLRQLLAPVVKEIIDDKSLIINTNPVEVYKAWVNQLETQTGEASKLPYDVTTEQALTYPEVKNKLEASIENLRRVTDKVLNSIISSLDLLPYGLRYIAKVLKNSIHEKFPDATEDELLKIVGNLLYYRYMNPAIVAPDGFDIIDMTAGGQINSDQRRNLGSVAKVLQHAASNKLFEGENEHLSSMNNYLSETYQEFRKYFKEACNVPEPEEKFNMDKYTDLVTVSKPVIYISIEEIISTHSLLLEHQDAIAPEKNDLLSELLGSLGEVPTVESFLGEGAVDPNDPNKANTLSQLSKTEISLVLTSKYDIEDGEAIDSRSLMIKTKKLIIDVIRNQPGNTLTEILETPATAQQEVDHATDMVSRAMIDSRTPEEMKHSQSMIEDAQLPLEQKKRKIQRNLRTLEQTGHVSSENKYQDILNEIAKDIRNQRIYRKLRKAELAKLQQTLNALNKKAAFYEEQINYYDTYIKTCLDNLKRKNTRRSIKLDGKGEPKGAKRAKPVKYTAAKLHEKGVLLDIDDLQTNQFKNVTFDIIATEDVGIFDVRSKFLGVEMEKVQLNIQDLLQMQYEGVAVMKMFDKVKVNVNLLIYLLNKKFYGK
"
misc_feature 268..270
/gene="IQGAP2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q13576.4); phosphorylation site"
misc_feature 346..690
/gene="IQGAP2"
/note="Calponin homology domain; actin-binding domain
which may be present as a single copy or in tandem repeats
(which increases binding affinity). The CH domain is found
in cytoskeletal and signal transduction proteins,
including actin-binding proteins like...; Region: CH;
cd00014"
/db_xref="CDD:28898"
misc_feature order(346..351,355..363,370..372,379..381,571..576,
583..585,592..594,598..600,649..654,661..666,670..675,
682..687)
/gene="IQGAP2"
/note="putative actin binding surface [polypeptide
binding]; other site"
/db_xref="CDD:28898"
misc_feature 2287..2352
/gene="IQGAP2"
/note="Calmodulin-binding motif; Region: IQ; smart00015"
/db_xref="CDD:197470"
misc_feature 2998..4014
/gene="IQGAP2"
/note="IQGAP2 is a member of the IQGAP family that
contains a calponin-homology (CH) domain which binds
F-actin, IQGAP-specific repeat, a single WW domain, four
IQ motifs which mediate interactions with calmodulin, and
a Ras-GTPase-activating protein (GAP)...; Region:
RasGAP_IQGAP2; cd05131"
/db_xref="CDD:88571"
misc_feature 4318..4725
/gene="IQGAP2"
/note="RasGAP C-terminus; Region: RasGAP_C; pfam03836"
/db_xref="CDD:146459"
variation 223
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370320521"
exon 269..368
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 279
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372040696"
variation 281
/gene="IQGAP2"
/replace="a"
/replace="t"
/db_xref="dbSNP:148247178"
variation 315
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376030929"
variation 320
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369302838"
variation 321
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:141290804"
variation 324
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373606679"
variation 345
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:139165349"
exon 369..525
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 415
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:139440648"
variation 431
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369077131"
variation 449
/gene="IQGAP2"
/replace="a"
/replace="c"
/db_xref="dbSNP:373370094"
variation 507
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:148174773"
variation 517
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:376517879"
exon 526..603
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 544
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:192694811"
variation 561
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:115631027"
variation 578
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:146065067"
exon 604..680
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 634
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200135774"
variation 662
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140724393"
variation 673
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201291442"
exon 681..748
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 684
/gene="IQGAP2"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1131232"
variation 700
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375045201"
variation 709
/gene="IQGAP2"
/replace="a"
/replace="c"
/db_xref="dbSNP:202016097"
exon 749..862
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 756
/gene="IQGAP2"
/replace="a"
/replace="t"
/db_xref="dbSNP:143699665"
variation 775
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:201127307"
variation 842
/gene="IQGAP2"
/replace="a"
/replace="t"
/db_xref="dbSNP:34833676"
exon 863..1041
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 864
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:148953280"
variation 865
/gene="IQGAP2"
/replace="c"
/replace="g"
/db_xref="dbSNP:201525266"
variation 872
/gene="IQGAP2"
/replace="a"
/replace="c"
/db_xref="dbSNP:111655897"
variation 892
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199711600"
variation 899
/gene="IQGAP2"
/replace="a"
/replace="c"
/db_xref="dbSNP:374036965"
variation 921
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:200319462"
variation 922
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:147531108"
variation 943
/gene="IQGAP2"
/replace="a"
/replace="c"
/db_xref="dbSNP:201309376"
variation 977
/gene="IQGAP2"
/replace="a"
/replace="c"
/db_xref="dbSNP:376703431"
variation 1005
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:151083253"
exon 1042..1129
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 1090
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373714955"
variation 1095
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:142653944"
variation 1108
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377573714"
exon 1130..1293
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 1137
/gene="IQGAP2"
/replace="a"
/replace="t"
/db_xref="dbSNP:141398992"
variation 1154
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371271172"
variation 1159
/gene="IQGAP2"
/replace="c"
/replace="g"
/db_xref="dbSNP:137915513"
variation 1166
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141913830"
variation 1167
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:371048498"
variation 1180
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150086790"
variation 1187
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:375606140"
variation 1227
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:368353933"
variation 1260
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:369254878"
variation 1274
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373251555"
variation 1277
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:181258165"
exon 1294..1454
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 1309
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199507670"
variation 1354
/gene="IQGAP2"
/replace="c"
/replace="g"
/db_xref="dbSNP:376410723"
variation 1377
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:140342604"
variation 1414
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:138552758"
variation 1433
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:374157441"
variation 1454
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377512838"
exon 1455..1579
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 1475
/gene="IQGAP2"
/replace="a"
/replace="c"
/db_xref="dbSNP:373926073"
variation 1489
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:149265572"
variation 1502
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:144559978"
variation 1504
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:137988082"
variation 1546
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:73766943"
variation 1553
/gene="IQGAP2"
/replace="a"
/replace="t"
/db_xref="dbSNP:376098110"
exon 1580..1743
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 1581
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370560776"
variation 1586
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:7722711"
variation 1587
/gene="IQGAP2"
/replace="a"
/replace="c"
/db_xref="dbSNP:139972010"
variation 1604
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201516054"
variation 1612
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368535679"
variation 1617
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:11553735"
variation 1658
/gene="IQGAP2"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:3822530"
variation 1668
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:371624599"
variation 1686
/gene="IQGAP2"
/replace="a"
/replace="t"
/db_xref="dbSNP:34535949"
variation 1692
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:36087650"
variation 1700
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:374553088"
exon 1744..1834
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 1763
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:139421974"
variation 1794
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:2431351"
variation 1798
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:145465543"
variation 1803
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:2431352"
variation 1810
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368255249"
variation 1814
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:143443092"
variation 1816
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:2909888"
variation 1833
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376719498"
exon 1835..2002
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 1845
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140885056"
variation 1968
/gene="IQGAP2"
/replace="a"
/replace="c"
/db_xref="dbSNP:144805046"
exon 2003..2145
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 2008
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369081736"
variation 2013
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:2910819"
variation 2049
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:150366195"
variation 2067
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373417790"
variation 2106
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:138150085"
variation 2109
/gene="IQGAP2"
/replace="c"
/replace="g"
/db_xref="dbSNP:2455230"
variation 2113
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:181383719"
variation 2115
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:138758867"
variation 2142
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:140853165"
exon 2146..2316
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 2160
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:145113303"
variation 2161
/gene="IQGAP2"
/replace="c"
/replace="g"
/db_xref="dbSNP:35544895"
variation 2180
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375933191"
variation 2190
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368537160"
variation 2207
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:111675976"
variation 2209
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373264194"
variation 2223
/gene="IQGAP2"
/replace="a"
/replace="t"
/db_xref="dbSNP:76713554"
variation 2224
/gene="IQGAP2"
/replace="a"
/replace="c"
/db_xref="dbSNP:200306861"
variation 2240
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371907881"
variation 2243
/gene="IQGAP2"
/replace="a"
/replace="c"
/db_xref="dbSNP:376526797"
variation 2259
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:147514296"
variation 2261
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:148549280"
variation 2278
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368456798"
variation 2301
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:201322324"
variation 2305
/gene="IQGAP2"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:79871053"
variation 2307
/gene="IQGAP2"
/replace="c"
/replace="g"
/db_xref="dbSNP:372017854"
exon 2317..2400
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 2341
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:375342547"
variation 2342
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:151128648"
variation 2360
/gene="IQGAP2"
/replace="c"
/replace="g"
/db_xref="dbSNP:139973941"
variation 2362
/gene="IQGAP2"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:35366349"
variation 2369
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:199827196"
variation 2392
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:2431363"
exon 2401..2472
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 2416
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373704383"
variation 2417
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:112380748"
variation 2419
/gene="IQGAP2"
/replace="a"
/replace="t"
/db_xref="dbSNP:199567785"
variation 2441
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377569601"
exon 2473..2542
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 2503
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:377698465"
variation 2511
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371448195"
exon 2543..2751
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 2586
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140923952"
variation 2589
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368438960"
variation 2636
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372033178"
variation 2730
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373890004"
exon 2752..2901
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 2757
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:144641342"
variation 2766
/gene="IQGAP2"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:253093"
variation 2801
/gene="IQGAP2"
/replace="a"
/replace="t"
/db_xref="dbSNP:200795118"
variation 2825
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201059481"
variation 2831
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:201642967"
variation 2839
/gene="IQGAP2"
/replace="a"
/replace="t"
/db_xref="dbSNP:200362498"
variation 2869
/gene="IQGAP2"
/replace="c"
/replace="g"
/db_xref="dbSNP:34968964"
variation 2898
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:148071477"
exon 2902..3065
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 2903
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:34950321"
variation 2963
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:146422169"
variation 2990
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201385729"
variation 2998
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:188847941"
variation 3010
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:377130667"
variation 3011
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:138998729"
exon 3066..3290
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 3099
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:143119515"
variation 3147
/gene="IQGAP2"
/replace="a"
/replace="c"
/db_xref="dbSNP:143839039"
variation 3149
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:148082215"
variation 3185
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:374151074"
variation 3202
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:138211969"
variation 3204
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:76979655"
variation 3213
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:144328533"
variation 3240
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201177978"
exon 3291..3431
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 3313
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376921394"
variation 3372
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:200705388"
variation 3377
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:2287932"
variation 3384
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:200616670"
variation 3387
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:143869334"
variation 3388
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:145945229"
variation 3397
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:375412628"
variation 3406
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:139792880"
variation 3431
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:200940839"
exon 3432..3516
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 3449
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368432599"
variation 3456
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:145178581"
variation 3472
/gene="IQGAP2"
/replace="a"
/replace="t"
/db_xref="dbSNP:371564584"
variation 3496
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:151182090"
exon 3517..3749
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 3543
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:112301923"
variation 3598
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140188703"
variation 3614
/gene="IQGAP2"
/replace="a"
/replace="c"
/db_xref="dbSNP:199960498"
variation 3617
/gene="IQGAP2"
/replace="c"
/replace="g"
/db_xref="dbSNP:201879277"
variation 3663
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:375463609"
variation 3697
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:149940408"
variation 3701
/gene="IQGAP2"
/replace="a"
/replace="t"
/db_xref="dbSNP:201262213"
variation 3740
/gene="IQGAP2"
/replace="a"
/replace="t"
/db_xref="dbSNP:369959488"
exon 3750..3882
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 3750
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:202217286"
variation 3773
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:10454915"
variation 3788
/gene="IQGAP2"
/replace="a"
/replace="c"
/db_xref="dbSNP:142296855"
variation 3802
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373729319"
variation 3804
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368996458"
variation 3824
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:146071185"
variation 3832
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201192766"
variation 3867
/gene="IQGAP2"
/replace="a"
/replace="c"
/db_xref="dbSNP:457937"
exon 3883..3985
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 3920
/gene="IQGAP2"
/replace="a"
/replace="c"
/db_xref="dbSNP:373530105"
variation 3951
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:34076951"
variation 3970
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:185223948"
exon 3986..4127
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 4018
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:141592712"
variation 4079
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:143650393"
variation 4093
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376614167"
variation 4117
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:147002427"
exon 4128..4215
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 4156
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373730789"
variation 4190
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:367797221"
variation 4192
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:192621142"
STS 4193..4660
/gene="IQGAP2"
/standard_name="Iqgap2"
/db_xref="UniSTS:256441"
variation 4208
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:148122303"
exon 4216..4428
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 4220
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141880135"
variation 4226
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377308848"
variation 4283
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:61739347"
variation 4293
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:182860123"
variation 4301
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372408098"
variation 4357
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:17681908"
variation 4362
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:142258030"
variation 4374
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:146380825"
variation 4415
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:139757749"
variation 4416
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:369344159"
variation 4421
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373452467"
exon 4429..4589
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 4436
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:189501812"
variation 4497
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:374869048"
variation 4509
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:143210414"
variation 4517
/gene="IQGAP2"
/replace="a"
/replace="c"
/db_xref="dbSNP:181359610"
variation 4519
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:144434710"
variation 4556
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369078465"
exon 4590..4727
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 4598
/gene="IQGAP2"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:34592828"
variation 4612
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:142548903"
STS 4614..4813
/gene="IQGAP2"
/standard_name="MARC_17727-17728:1031758304:1"
/db_xref="UniSTS:268387"
variation 4626
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201596632"
variation 4641
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:190325896"
variation 4647
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150986204"
variation 4649
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:142120814"
variation 4686
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377118954"
variation 4700
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:370452996"
variation 4701
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:374871150"
variation 4713
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:144405948"
variation 4714
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:147860676"
variation 4724
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199687430"
exon 4728..4836
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 4745
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:141420081"
variation 4756
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368828240"
variation 4787
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:371330018"
variation 4792
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368752328"
variation 4812
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150409607"
variation 4814
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201571668"
variation 4818
/gene="IQGAP2"
/replace="c"
/replace="g"
/db_xref="dbSNP:145165340"
variation 4824
/gene="IQGAP2"
/replace="a"
/replace="t"
/db_xref="dbSNP:375336707"
variation 4829
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201167699"
exon 4837..5769
/gene="IQGAP2"
/inference="alignment:Splign:1.39.8"
variation 4856
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:202207724"
variation 4921
/gene="IQGAP2"
/replace="c"
/replace="g"
/db_xref="dbSNP:372834701"
STS 4965..5115
/gene="IQGAP2"
/standard_name="RH70668"
/db_xref="UniSTS:82051"
variation 4967
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:377567632"
variation 4973
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370207767"
variation 5058..5059
/gene="IQGAP2"
/replace=""
/replace="t"
/db_xref="dbSNP:75247437"
variation 5066
/gene="IQGAP2"
/replace="a"
/replace="t"
/db_xref="dbSNP:463188"
variation 5070
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:464494"
variation 5116
/gene="IQGAP2"
/replace=""
/replace="t"
/db_xref="dbSNP:5868837"
variation 5129
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:139058911"
variation 5154..5155
/gene="IQGAP2"
/replace=""
/replace="g"
/db_xref="dbSNP:35189434"
variation 5235
/gene="IQGAP2"
/replace="c"
/replace="g"
/db_xref="dbSNP:74508809"
variation 5285
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:185366183"
variation 5294
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:12735"
variation 5318
/gene="IQGAP2"
/replace="c"
/replace="t"
/db_xref="dbSNP:371685030"
variation 5353
/gene="IQGAP2"
/replace="a"
/replace="g"
/db_xref="dbSNP:190155250"
variation 5502
/gene="IQGAP2"
/replace="a"
/replace="c"
/db_xref="dbSNP:182824032"
STS 5530..5730
/gene="IQGAP2"
/standard_name="D5S2432"
/db_xref="UniSTS:78227"
variation 5673..5674
/gene="IQGAP2"
/replace=""
/replace="t"
/db_xref="dbSNP:201953417"
variation 5679
/gene="IQGAP2"
/replace="g"
/replace="t"
/db_xref="dbSNP:72761042"
variation 5753..5755
/gene="IQGAP2"
/replace=""
/replace="ttac"
/db_xref="dbSNP:144991649"
variation 5753
/gene="IQGAP2"
/replace=""
/replace="ttac"
/db_xref="dbSNP:34872448"
variation 5760
/gene="IQGAP2"
/replace=""
/replace="ctta"
/db_xref="dbSNP:1610959"
ORIGIN
gagggaggagagttcacttttacttcagtgtcagcgcgcggcggccgtggctggctctggcgagagagcaccgagggagtgggtcgcagatcttcgggcggctaggggaaatcggcgagaggcgggatccgagcgcgccggcggggcgcagagcccgcgagcctggccagcgagggtagccgcggggggcgcgccccgggcgggcccccggagacgcgcaggatgccacacgaagagctgccgtcgctgcagagaccccgctatggctctattgtggacgatgaaaggctctctgcagaggagatggatgagaggaggcggcagaacattgcttatgaatatctgtgccacttagaggaagccaaaaggtggatggaagtttgcttagttgaagaattgccaccaaccactgaattggaagaagggctccggaatggagtttaccttgcaaagttagccaagttctttgccccgaaaatggtatcagagaaaaagatctatgatgtggaacaaacacgttataagaagtctggccttcattttcgacacacagataataccgtccagtggttaagagcgatggagtctattggtctacccaagatattttatccagaaacaacagatgtctatgatcggaaaaacataccaagaatgatatattgcattcacgcactgagtttgtatctgttcaaactaggaatagcaccccagatccaggatttgttgggcaaagtagacttcacagaggaggaaatcagtaatatgagaaaagaacttgagaaatatggaatacagatgccatctttcagcaaaataggtggtattctggccaatgaactgtccgtggatgaagctgcattacatgctgcagttatagccattaatgaagcagttgaaaaaggaatagcagagcaaaccgttgtaacactaagaaacccaaatgcggttttaactttagtggatgacaaccttgcaccagaatatcagaaagaactctgggatgccaaaaagaaaaaagaggaaaatgcaagactgaagaatagctgtatttcagaagaagaaagagatgcttatgaagaactgctgacacaagcagaaatccaaggcaatattaataaagtcaacaggcaggctgcagtggaccatatcaatgctgtcattccggaaggtgaccccgagaatacgctgcttgcactgaagaaaccagaggcccagctgcctgctgtttatccctttgctgctgccatgtatcagaacgaacttttcaacctccagaaacagaacaccatgaactacttggcccacgaggagcttttgattgctgtggaaatgttgtctgctgttgctttactaaaccaggccttggaaagcaacgatcttgtgtctgtgcagaatcaactcagaagccccgcaataggcttaaacaatctggacaaggcatatgtggaacgttatgcaaacacactactctctgttaaactagaagttttatcccaagggcaagataacttaagctggaatgaaattcagaattgtattgatatggttaatgctcaaattcaagaagaaaatgaccgagttgtagctgtagggtacatcaatgaagctattgatgaagggaatcctttgaggactttagaaactttgctcctacctactgcgaatattagtgatgtggacccagcccatgcccagcactaccaggatgttttataccatgctaaatcacagaaactcggagactctgagagtgtttccaaagtgctttggctggatgagatacagcaagccgtcgatgatgccaacgtggacgaggacagagcaaaacaatgggttactctggtggttgatgttaatcagtgtttggaaggaaaaaaatcaagtgatattttgtctgtattgaagtcttccacttctaatgcaaatgacataatcccggagtgtgctgacaaatactatgatgcccttgtgaaggcaaaagagctcaaatctgaaagagtgtctagtgacggttcatggctcaaactcaacctgcacaaaaaatatgactactattacaacactgattcaaaagagagttcctgggtcacacctgaatcatgcttgtataaagaatcatggctcacaggaaaagaaatcgaggacattattgaggaagtcacagtaggttacattcgtgagaatatatggtctgcttcagaagagttgcttcttcgctttcaagccacaagctcaggacccatccttagggaagagtttgaagctagaaaatcatttttgcatgaacaagaagagaatgtggtcaaaatacaggctttttggaaaggatataaacaacggaaggagtatatgcacaggcggcaaacgttcattgataatactgattctattgtgaagattcagtcctggttccgaatggcaactgcaagaaagagctatctttcaagactacagtatttcagagatcataataatgaaattgtgaaaatacagtcactgttgagagcgaacaaagctagagatgactacaaaacattggttggctctgaaaacccaccattaacagtaattcgcaaatttgtatacctgctggaccaaagtgatttggatttccaggaggaactagaggttgcacgattaagggaagaagtagtgaccaagatcagggccaatcaacagctggaaaaagacctgaacctgatggacatcaagattggactgctggtgaagaacaggatcacactagaggatgtaatttcacacagtaaaaagctgaacaagaaaaaaggaggagaaatggaaatactgaataacaccgacaaccaaggaataaaaagtttgagtaaggagaggagaaaaacactagaaacatatcagcagctgttttaccttttacagaccaaccctttatacttggctaagctgattttccagatgccacagaacaagtccactaaatttatggatactgttattttcacactatataattatgcctctaatcagcgagaagaatatctacttctcaagctttttaaaactgctctggaggaagaaataaaatcaaaagtggaccaggtacaggacatagttactggtaaccctacagtcatcaagatggtcgtcagcttcaatagaggtgcccggggacagaacaccctgcgccaactcctggctccagtggtaaaagagatcatcgacgacaagtcgctgattatcaacacaaaccctgtagaggtgtacaaggcttgggtgaaccaactagaaacacagactggagaggccagcaagttgccttatgatgtgaccacagaacaagctctaacatacccagaagtgaaaaataaactggaggcttccattgagaacctgagaagggtcaccgacaaagtcctgaattctatcatttcttcccttgatctactgccttatggattgaggtatatagccaaagtactgaagaattcgatccatgagaaattccccgatgcaacagaagatgagctattaaagattgttggaaacctcctgtactatcggtacatgaatccagccattgtagctccagatggctttgatatcatcgacatgacagctggaggtcagataaattctgaccaaaggagaaacttaggatcagtggccaaggttcttcagcacgcagcctccaacaagctgtttgaaggagaaaatgagcatctctcatctatgaacaattatttatcagagacgtatcaggaattcaggaaatatttcaaagaagcatgtaatgtccctgagccagaagagaagtttaatatggacaaatacacagacctggtgacagtcagcaaaccagtcatttatatttcaattgaagaaatcatcagcacacactcactcctgttggaacaccaggatgcaattgcccctgagaaaaatgacttactgagtgaattgctggggtcgctgggagaggtgccaaccgtggaatcttttcttggggaaggagcagttgaccccaatgaccctaacaaggcaaatacactaagtcagctttcaaagaccgagatttctcttgtcttgacaagcaaatatgacatagaggacggtgaagctatagatagccgaagcctcatgataaagaccaagaagctgataattgatgtgatccggaaccagccagggaacacattgacagaaatcttagagacaccagcaactgcgcaacaggaggtagaccatgccacggacatggtgagccgtgcaatgatagattccaggactccagaagaaatgaagcatagccaatctatgattgaagatgcacagctgcctcttgagcagaagaagaggaaaatccagaggaatcttcggacgttggaacagactggacacgtgtcatccgaaaataaataccaagacattctcaatgagattgccaaggatattcgaaatcaaagaatctatcgtaagcttcgaaaagctgaattggcaaaacttcagcagaccctgaatgcacttaacaagaaggcagcattttatgaagagcaaatcaattattatgacacctacataaagacttgtttagacaacttaaaaagaaaaaatactcggagatcaattaaactagatggaaaaggagaacccaaaggggcgaagagagcgaagccagtgaagtacactgcagcaaagctgcatgagaaaggtgtcctgctagatatagatgatcttcaaacaaaccagtttaagaatgttacatttgatatcatagctactgaagatgtaggcattttcgatgtaagatcaaaattccttggtgttgagatggaaaaggtgcaactcaatattcaggatttacttcagatgcaatatgaaggagtagctgtaatgaaaatgtttgataaggttaaagtgaatgtaaaccttctcatatacctgctgaacaagaagttctatggaaagtgaagtgcctacagaaatttcttggattctgtatcatctggattaggaaatgaatttgtttaatatttttgtttttaaacatgattgaaatcactgcttataaatgtgtgatttttttaaaacgaccaaaactgttctgaagaatgtacccaggtgcctttttgctaatttgatactataatagaatgagacataaaatgaattaatggaaacatatccacactgtactgtgatataggtactctgatttaaaactttggacatcctgtgatctgttttaaagttggggggtgggaaatttagctgactagggacaaacatgtaaacctattttcctatgaaaaaaattttaaatgtcccacttgaataacgtaattcttcatagtttttttaatctatggataaatggaaacctaattatttgtaatgaattatttagacagttctaagccctgtcttctgggagttatcaattttaaagagaacttttgtgcaattcaaatgaagtttttataagtaattgaaaatgacaacacaataacactttctgtataaaagtatatattttatgtgatttattcctactaaatgaaagtgcactactgcctcatgtaaagactcttgcacgcagagcctttaagtgactaaggaacaacatagatagtgagcatagtccccacctccacccctcacaatttatttgaatacttcaattgtgcctctcaattttttgtaatgctaaaaaatcagtatctagatggtttttaaatgtattctctggaaattgttttatgtaaaataaatgttacttaattccattaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:10788 -> Molecular function: GO:0003779 [actin binding] evidence: TAS
GeneID:10788 -> Molecular function: GO:0005095 [GTPase inhibitor activity] evidence: TAS
GeneID:10788 -> Molecular function: GO:0005099 [Ras GTPase activator activity] evidence: IEA
GeneID:10788 -> Molecular function: GO:0005516 [calmodulin binding] evidence: IEA
GeneID:10788 -> Biological process: GO:0007165 [signal transduction] evidence: TAS
GeneID:10788 -> Biological process: GO:0007264 [small GTPase mediated signal transduction] evidence: IEA
GeneID:10788 -> Cellular component: GO:0005874 [microtubule] evidence: IDA
GeneID:10788 -> Cellular component: GO:0005902 [microvillus] evidence: IEA
GeneID:10788 -> Cellular component: GO:0015629 [actin cytoskeleton] evidence: TAS
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