Home |
Help |
Advanced search
2024-04-24 10:17:08, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_006595 3777 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens apoptosis inhibitor 5 (API5), transcript variant 2,
mRNA.
ACCESSION NM_006595 NM_021112
VERSION NM_006595.3 GI:219283149
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3777)
AUTHORS Han,B.G., Kim,K.H., Lee,S.J., Jeong,K.C., Cho,J.W., Noh,K.H.,
Kim,T.W., Kim,S.J., Yoon,H.J., Suh,S.W., Lee,S. and Lee,B.I.
TITLE Helical repeat structure of apoptosis inhibitor 5 reveals
protein-protein interaction modules
JOURNAL J. Biol. Chem. 287 (14), 10727-10737 (2012)
PUBMED 22334682
REMARK GeneRIF: structure and function of API5
REFERENCE 2 (bases 1 to 3777)
AUTHORS Wang,Z., Liu,H., Liu,B., Ma,W., Xue,X., Chen,J. and Zhou,Q.
TITLE Gene expression levels of CSNK1A1 and AAC-11, but not NME1, in
tumor tissues as prognostic factors in NSCLC patients
JOURNAL Med. Sci. Monit. 16 (8), CR357-CR364 (2010)
PUBMED 20671611
REMARK GeneRIF: The prognostic significance of the genes casein kinase 2
alpha subunit (CSNK2A1), anti-apoptosis clone-11 (AAC-11), and
tumor metastasis suppressor NME1 in completely resected non-small
cell lung cancer (NSCLC) patients, was analysed.
REFERENCE 3 (bases 1 to 3777)
AUTHORS Ren,K., Zhang,W., Shi,Y. and Gong,J.
TITLE Pim-2 activates API-5 to inhibit the apoptosis of hepatocellular
carcinoma cells through NF-kappaB pathway
JOURNAL Pathol. Oncol. Res. 16 (2), 229-237 (2010)
PUBMED 19821157
REMARK GeneRIF: we infer that Pim-2 could activate API-5 to inhibit the
apoptosis of liver cells, and NF-kappaB is the key regulator
REFERENCE 4 (bases 1 to 3777)
AUTHORS Need,A.C., Attix,D.K., McEvoy,J.M., Cirulli,E.T., Linney,K.L.,
Hunt,P., Ge,D., Heinzen,E.L., Maia,J.M., Shianna,K.V., Weale,M.E.,
Cherkas,L.F., Clement,G., Spector,T.D., Gibson,G. and
Goldstein,D.B.
TITLE A genome-wide study of common SNPs and CNVs in cognitive
performance in the CANTAB
JOURNAL Hum. Mol. Genet. 18 (23), 4650-4661 (2009)
PUBMED 19734545
REFERENCE 5 (bases 1 to 3777)
AUTHORS Rigou,P., Piddubnyak,V., Faye,A., Rain,J.C., Michel,L., Calvo,F.
and Poyet,J.L.
TITLE The antiapoptotic protein AAC-11 interacts with and regulates
Acinus-mediated DNA fragmentation
JOURNAL EMBO J. 28 (11), 1576-1588 (2009)
PUBMED 19387494
REMARK GeneRIF: The authors report here that AAC-11, a survival protein
whose expression prevents apoptosis that occurs on deprivation of
growth factors, physiologically binds to Acinus and prevents
Acinus-mediated DNA fragmentation.
REFERENCE 6 (bases 1 to 3777)
AUTHORS Li,Z., Hu,C.Y., Mo,B.Q., Xu,J.D. and Zhao,Y.
TITLE [Effect of beta-carotene on gene expression of breast cancer cells]
JOURNAL Ai Zheng 22 (4), 380-384 (2003)
PUBMED 12703993
REFERENCE 7 (bases 1 to 3777)
AUTHORS Van den Berghe,L., Laurell,H., Huez,I., Zanibellato,C., Prats,H.
and Bugler,B.
TITLE FIF [fibroblast growth factor-2 (FGF-2)-interacting-factor], a
nuclear putatively antiapoptotic factor, interacts specifically
with FGF-2
JOURNAL Mol. Endocrinol. 14 (11), 1709-1724 (2000)
PUBMED 11075807
REFERENCE 8 (bases 1 to 3777)
AUTHORS Kim,J.W., Cho,H.S., Kim,J.H., Hur,S.Y., Kim,T.E., Lee,J.M.,
Kim,I.K. and Namkoong,S.E.
TITLE AAC-11 overexpression induces invasion and protects cervical cancer
cells from apoptosis
JOURNAL Lab. Invest. 80 (4), 587-594 (2000)
PUBMED 10780674
REFERENCE 9 (bases 1 to 3777)
AUTHORS Gianfrancesco,F., Esposito,T., Ciccodicola,A., D'Esposito,M.,
Mazzarella,R., D'Urso,M. and Forabosco,A.
TITLE Molecular cloning and fine mapping of API5L1, a novel human gene
strongly related to an antiapoptotic gene
JOURNAL Cytogenet. Cell Genet. 84 (3-4), 164-166 (1999)
PUBMED 10393420
REFERENCE 10 (bases 1 to 3777)
AUTHORS Tewari,M., Yu,M., Ross,B., Dean,C., Giordano,A. and Rubin,R.
TITLE AAC-11, a novel cDNA that inhibits apoptosis after growth factor
withdrawal
JOURNAL Cancer Res. 57 (18), 4063-4069 (1997)
PUBMED 9307294
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DA104687.1, BC017709.1 and
BF115210.1.
On Jan 1, 2009 this sequence version replaced gi:41393590.
Summary: This gene encodes an apoptosis inhibitory protein whose
expression prevents apoptosis after growth factor deprivation. This
protein suppresses the transcription factor E2F1-induced apoptosis
and also interacts with, and negatively regulates Acinus, a nuclear
factor involved in apoptotic DNA fragmentation. Its depletion
enhances the cytotoxic action of the chemotherapeutic drugs.
Multiple alternatively spliced transcript variants encoding
different isoforms have been identified. [provided by RefSeq, Aug
2011].
Transcript Variant: This variant (2) lacks a small segment in the
3' coding region that results in a frameshift, compared to variant
1. The resulting protein (isoform b) has a shorter and distinct
C-terminus, compared to isoform a.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: Y15906.1, AY311389.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025082 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-80 DA104687.1 1-80
81-3758 BC017709.1 1-3678
3759-3777 BF115210.1 1-19 c
FEATURES Location/Qualifiers
source 1..3777
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="11"
/map="11p11.2"
gene 1..3777
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/note="apoptosis inhibitor 5"
/db_xref="GeneID:8539"
/db_xref="HGNC:594"
/db_xref="HPRD:16500"
/db_xref="MIM:609774"
exon 1..242
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/inference="alignment:Splign:1.39.8"
variation 22
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="g"
/replace="t"
/db_xref="dbSNP:113811140"
variation 58
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="g"
/db_xref="dbSNP:368093818"
variation 77
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:5743211"
variation 83
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="t"
/db_xref="dbSNP:5743212"
variation 87
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="g"
/replace="t"
/db_xref="dbSNP:184841117"
variation 126
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="g"
/db_xref="dbSNP:377415422"
misc_feature 141..143
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/note="upstream in-frame stop codon"
variation 150
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:374625952"
CDS 174..1688
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/note="isoform b is encoded by transcript variant 2;
fibroblast growth factor 2-interacting factor 2;
migration-inducing protein MIG8; FIF; antiapoptosis clone
11 protein; cell migration-inducing gene 8 protein"
/codon_start=1
/product="apoptosis inhibitor 5 isoform b"
/protein_id="NP_006586.1"
/db_xref="GI:5729730"
/db_xref="CCDS:CCDS31465.1"
/db_xref="GeneID:8539"
/db_xref="HGNC:594"
/db_xref="HPRD:16500"
/db_xref="MIM:609774"
/translation="
MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLGTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVEIGQKRASEDTTSGSPPKKSSAGPKRDARQIYNPPSGKYSSNLGNFNYERSLQGK
"
misc_feature 177..1253
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9BZZ5.3);
Region: ARM-like and Heat-like helical repeats"
misc_feature 177..179
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/experiment="experimental evidence, no additional details
recorded"
/note="Not acetylated; propagated from
UniProtKB/Swiss-Prot (Q9BZZ5.3); other site"
misc_feature 183..1652
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/note="Apoptosis inhibitory protein 5 (API5); Region:
API5; pfam05918"
/db_xref="CDD:114630"
misc_feature 381..641
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/note="HEAT repeats; Region: HEAT_2; pfam13646"
/db_xref="CDD:205823"
misc_feature 924..926
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-acetyllysine; propagated from
UniProtKB/Swiss-Prot (Q9BZZ5.3); acetylation site"
misc_feature 1281..1346
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9BZZ5.3);
Region: Leucine-zipper"
misc_feature 1533..1598
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9BZZ5.3);
Region: Nuclear localization signal"
misc_feature 1551..1553
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1554..1556
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1557..1559
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9BZZ5.3); phosphorylation site"
misc_feature 1557..1559
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1563..1565
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9BZZ5.3); phosphorylation site"
misc_feature 1563..1565
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1563..1565
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
exon 243..404
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/inference="alignment:Splign:1.39.8"
variation 253
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:200771952"
variation 286
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:35999189"
variation 314
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:374835296"
exon 405..498
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/inference="alignment:Splign:1.39.8"
variation 412
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:199828377"
variation 419
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:202237645"
variation 458
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:1143463"
exon 499..564
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/inference="alignment:Splign:1.39.8"
variation 529
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:145077695"
exon 565..716
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/inference="alignment:Splign:1.39.8"
variation 566
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:201125045"
STS 569..725
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/standard_name="RH65627"
/db_xref="UniSTS:81284"
variation 651
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="c"
/db_xref="dbSNP:76787103"
variation 651
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="c"
/db_xref="dbSNP:111361790"
variation 656
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:200627115"
variation 686
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:140654326"
variation 712
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:375559166"
exon 717..923
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/inference="alignment:Splign:1.39.8"
variation 738
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="g"
/db_xref="dbSNP:1804963"
variation 770
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="t"
/db_xref="dbSNP:377763153"
STS 786..867
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/standard_name="GDB:451846"
/db_xref="UniSTS:99411"
variation 827
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:112521686"
variation 856
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:369837996"
variation 908
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="c"
/db_xref="dbSNP:201696733"
exon 924..1028
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/inference="alignment:Splign:1.39.8"
variation 944..945
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace=""
/replace="g"
/db_xref="dbSNP:36082968"
variation 976
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="g"
/db_xref="dbSNP:370568717"
variation 1000..1001
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace=""
/replace="c"
/db_xref="dbSNP:35214208"
exon 1029..1118
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/inference="alignment:Splign:1.39.8"
variation 1068
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:144200699"
variation 1071
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:5743240"
variation 1075
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:147759395"
variation 1095
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="c"
/db_xref="dbSNP:75380901"
exon 1119..1300
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/inference="alignment:Splign:1.39.8"
variation 1119
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="g"
/db_xref="dbSNP:371353181"
variation 1137
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="c"
/db_xref="dbSNP:200528483"
variation 1152
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:141137610"
variation 1181
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:146948287"
variation 1190
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:150964963"
variation 1237
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:372123869"
variation 1261
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:201035525"
variation 1281
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="g"
/db_xref="dbSNP:140542517"
exon 1301..1394
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/inference="alignment:Splign:1.39.8"
variation 1387
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:192394283"
exon 1395..1451
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/inference="alignment:Splign:1.39.8"
exon 1452..1528
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/inference="alignment:Splign:1.39.8"
variation 1468
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:377039218"
variation 1496
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:150466686"
exon 1529..1665
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/inference="alignment:Splign:1.39.8"
variation 1557
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="t"
/db_xref="dbSNP:183344229"
variation 1587
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="g"
/db_xref="dbSNP:376582287"
variation 1588
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="g"
/db_xref="dbSNP:369005910"
variation 1607
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:139347770"
variation 1637
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:377223822"
variation 1650
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:2862934"
exon 1666..3763
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/inference="alignment:Splign:1.39.8"
variation 1690
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:374457536"
variation 1728
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="g"
/db_xref="dbSNP:368631098"
variation 1788
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:372172690"
variation 1792
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="c"
/db_xref="dbSNP:191181328"
variation 2033
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="g"
/replace="t"
/db_xref="dbSNP:183520498"
variation 2142
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="c"
/db_xref="dbSNP:151199895"
variation 2294
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:189225401"
variation 2308
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:11544603"
variation 2320
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="g"
/replace="t"
/db_xref="dbSNP:193209177"
variation 2444..2445
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace=""
/replace="ta"
/db_xref="dbSNP:374650735"
variation 2485
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="c"
/db_xref="dbSNP:376343843"
variation 2526
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:72898985"
variation 2688
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:11544606"
variation 2704
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:376531554"
variation 2749
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:140359514"
variation 2795
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="g"
/replace="t"
/db_xref="dbSNP:369508239"
variation 2836
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="c"
/db_xref="dbSNP:190214487"
variation 2918
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace=""
/replace="t"
/db_xref="dbSNP:35080936"
variation 2958
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:5743257"
variation 2979
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="g"
/db_xref="dbSNP:5743258"
variation 3269
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:140790279"
variation 3282
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="a"
/replace="g"
/db_xref="dbSNP:144608994"
variation 3555
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="g"
/replace="t"
/db_xref="dbSNP:181717898"
STS 3558..3634
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/standard_name="RH36898"
/db_xref="UniSTS:83787"
STS 3591..3741
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/standard_name="RH11873"
/db_xref="UniSTS:92803"
variation 3591
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:14754"
variation 3666
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:143322264"
variation 3680
/gene="API5"
/gene_synonym="AAC-11; AAC11"
/replace="c"
/replace="t"
/db_xref="dbSNP:1056535"
polyA_signal 3740..3745
/gene="API5"
/gene_synonym="AAC-11; AAC11"
polyA_site 3763
/gene="API5"
/gene_synonym="AAC-11; AAC11"
ORIGIN
gtctttacgtagacgtcgggggcgcagccgcgctgtgcgcggtgactggcggctgcactggcggcagctggaggtgtaatagtgcgggtagtgggtttggagaagttccgaggcggcggtggcgccggtcaggacaaggatagcggaaccgggccctgggcttgtcgctcaccatgccgacagtagaggagctttaccgcaattatggcatcctggccgatgccacggagcaagtgggccagcataaagatgcctatcaagtgatattggatggtgtgaaaggtggtactaaggaaaagcgattagcagctcaatttattccgaaattctttaagcattttccagaattggctgattctgctatcaatgcacagttagacctctgtgaggatgaagatgtatctattcgacgtcaagcaattaaagaactgcctcaatttgccactggagaaaatcttcctcgagtggcagatatactaacgcaacttttgcagacagatgactctgcagaatttaacctagtgaacaatgccctattaagtatatttaaaatggatgcaaaagggactttaggtgggttgttcagccaaatacttcaaggagaggacattgttagagaacgagcaattaaattcctttctacaaaacttaagactttaccagatgaagtcttaacaaaggaagtggaagagcttatactaactgaatccaaaaaggtcctagaagatgtgactggtgaagaatttgttctatttatgaagatactgtctgggttaaaaagcttacagacagtgagtggaagacagcaacttgtagagttggtggctgaacaggccgacctagaacagaccttcaatccctcggatcctgactgtgtggacaggctcttacagtgcactcggcaggcagtacccctcttctctaaaaatgtccattccacaaggtttgtgacatatttctgtgagcaggttctccctaacctcggtaccttgactaccccagtggaaggtcttgatatacagttggaggtattgaaattgttggcggagatgagttcattttgtggtgacatggaaaaactagaaacaaatttaaggaaactatttgataagttattggaatacatgcccctccctccagaagaggcagaaaatggagagaatgctggtaatgaagaacccaagctacagttcagttatgtggaatgtttgttgtacagttttcaccagttgggccgaaaacttccagatttcttaacagccaaactgaatgcagaaaagctcaaagatttcaaaatcaggctgcagtactttgcacggggcctgcaagtttatatcagacaacttcgcttagctctccagggtaaaacgggtgaggccttaaaaacagaagagaacaagattaaagtcgttgcattgaaaataacaaacaatatcaatgttttaatcaaggatctcttccacattcctccttcttataagagcacagtaacactatcctggaaacctgtacaaaaggttgagattgggcaaaagagagccagtgaagatacaacttcaggttcaccacccaagaaatcttcagcaggaccaaaaagagatgccaggcagatttataaccctcccagtgggaaatatagcagcaatttgggcaactttaattatgagaggagccttcaggggaagtagaggtggccgaggttggggcacacgaggaaatcgtagtcggggaagactctactgaataagacatcagcattcttcagcattgtcatgagcttaatatacttaaattctactactcattggattgccggggatgtccctttaaacagactgctgccttcagctaaaaacttaatgttctttatacctttgtatgtatgacctacttttgtaacagaccatggttgtgtccaaggtaaaaccacagtgatatttttggatgctttgtctgcaatcttgacttgtttttgcagtatcattattcagacttcaaattgtgaatcttttaaacatcttgataatttgttgttgagagctgttcattctaaaatgtaatgaaattcagtctagttctgctgataaagatcatcagttttgaaaggttactgattttcctcttccctcttagttttttacccaatatatggagaagagtaatggtcaatcttaacattttgttttaattgtttaataaagctgctgggcagtggtgcagcattcctacctagtgtcataaaagcaaaatacttacatagctttcttaaaatataggaatgacattacatttttaggagaaagtaagttgctttgcaccgcctacttaattcttttccatatattgtgatacaaacttttgaatatggaatcttactatttgaatagaaatgtgtatgtataatatacatacatacataagcatatatgtgtgtgtgtgtgtgtatatatatatatatgcatgctgtgaaacttgactacacaacataaatcactttttaaattccaggaacgggtagtctgacacggtgattatccttttgaggctgaatccgttattaacttgttatttaggtttttactcccagtagcaagggattctaagttagttgcacttacatgattattgttatttaaaactaagaataaaggctgcattttcaaagataaattggaattgctgttggtgaaataacaaccaaaatactgaatctgatgtacatacaggtttctacaggaagagatggtataatttacaatttggagatttaataaccagggctacccagaaaaagtgacttgataacatggtaccaataagtaagggatgctctctcggtttgcttttgccactttcaagattttaacttctcaggttattaatcaaaattattgtataagttagccaatagaatttttaggttaaaacaacagatggggggtttgtggagtgtttaatgtcatgggcatttttagtagcatagaccctttgttctgcatttgaatgtttcgtatatttttgtttcacagttaatcttccctccccaagtttgctattcaaatcaactgcctgaatgacatttctagtagtctgatgtatttttctgaggaatagtttgtgattccaatgcaggtgtcttcattaccattacctctacactgcagaagaagcaaaactcctttattagaattactgcacatgtgtatggggaaaatagttctgaaaggctagaatgatacaagtgagcaaaagttggtcagcttggctatggagtggtggcaataatctctaaacattccaaaagaccatgagctgaacctaaactcccttggaatctgaacaaaggaatataaaattgccatttgaaaactgaccagctaatctggacctcagagatagatcagccagtggcccaaagccatttcaagtacagaaattatagagactacagctaaataaatttgaacattaaatataattttaccactttttgtctttataagcatatttgtaaactcagaactgagcagaagtgactttactttctcaagtttgatactgagttgactgttcccttatccctcacccttccccttccctttcctaaggcaatagtgcacaacttaggttatttttgcttccgaatttgaatgaaaaacttaatgccatggatttttttcttttgcaagacacctgtttatcatcttgtttaaatgtaaatgtccccttatgcttttgaaataaatttccttttgtaattttgaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:8539 -> Molecular function: GO:0017134 [fibroblast growth factor binding] evidence: IPI
GeneID:8539 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:8539 -> Biological process: GO:0043066 [negative regulation of apoptotic process] evidence: IMP
GeneID:8539 -> Biological process: GO:0043066 [negative regulation of apoptotic process] evidence: ISS
GeneID:8539 -> Biological process: GO:0043066 [negative regulation of apoptotic process] evidence: NAS
GeneID:8539 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:8539 -> Cellular component: GO:0005681 [spliceosomal complex] evidence: ISS
GeneID:8539 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
GeneID:8539 -> Cellular component: GO:0005737 [cytoplasm] evidence: NAS
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.