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2019-03-25 14:56:00, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_006377               6398 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens unc-13 homolog B (C. elegans) (UNC13B), mRNA.
ACCESSION   NM_006377
VERSION     NM_006377.3  GI:110611225
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6398)
  AUTHORS   Liu,X., Cheng,R., Verbitsky,M., Kisselev,S., Browne,A.,
            Mejia-Sanatana,H., Louis,E.D., Cote,L.J., Andrews,H., Waters,C.,
            Ford,B., Frucht,S., Fahn,S., Marder,K., Clark,L.N. and Lee,J.H.
  TITLE     Genome-wide association study identifies candidate genes for
            Parkinson's disease in an Ashkenazi Jewish population
  JOURNAL   BMC Med. Genet. 12, 104 (2011)
   PUBMED   21812969
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6398)
  AUTHORS   Goldenberg,N.M. and Silverman,M.
  TITLE     Rab34 and its effector munc13-2 constitute a new pathway modulating
            protein secretion in the cellular response to hyperglycemia
  JOURNAL   Am. J. Physiol., Cell Physiol. 297 (4), C1053-C1058 (2009)
   PUBMED   19641095
  REMARK    GeneRIF: mechanistic basis for high glucose-induced protein
            secretion is through interaction of munc13 and rab34, indicating a
            potentially critical role for this newly described pathway in the
            pathogenesis of DN.
REFERENCE   3  (bases 1 to 6398)
  AUTHORS   Dimova,K., Kalkhof,S., Pottratz,I., Ihling,C.,
            Rodriguez-Castaneda,F., Liepold,T., Griesinger,C., Brose,N.,
            Sinz,A. and Jahn,O.
  TITLE     Structural insights into the calmodulin-Munc13 interaction obtained
            by cross-linking and mass spectrometry
  JOURNAL   Biochemistry 48 (25), 5908-5921 (2009)
   PUBMED   19492809
  REMARK    GeneRIF: In the bound state, the hydrophobic anchor residue of the
            calmodulin (CaM)-binding motif in Munc13 contacts two distinct
            methionine residues in the carboxyl-terminal domain of CaM.
REFERENCE   4  (bases 1 to 6398)
  AUTHORS   Tregouet,D.A., Groop,P.H., McGinn,S., Forsblom,C., Hadjadj,S.,
            Marre,M., Parving,H.H., Tarnow,L., Telgmann,R., Godefroy,T.,
            Nicaud,V., Rousseau,R., Parkkonen,M., Hoverfalt,A., Gut,I.,
            Heath,S., Matsuda,F., Cox,R., Kazeem,G., Farrall,M., Gauguier,D.,
            Brand-Herrmann,S.M., Cambien,F., Lathrop,M. and Vionnet,N.
  CONSRTM   EURAGEDIC Consortium
  TITLE     G/T substitution in intron 1 of the UNC13B gene is associated with
            increased risk of nephropathy in patients with type 1 diabetes
  JOURNAL   Diabetes 57 (10), 2843-2850 (2008)
   PUBMED   18633107
  REMARK    GeneRIF: Data identified a polymorphism in the UNC13B gene
            associated with nephropathy. UNC13B mediates apopotosis in
            glomerular cells in the presence of hyperglycemia, an event
            occurring early in the development of nephropathy.
            GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   5  (bases 1 to 6398)
  AUTHORS   Speight,P. and Silverman,M.
  TITLE     Diacylglycerol-activated Hmunc13 serves as an effector of the
            GTPase Rab34
  JOURNAL   Traffic 6 (10), 858-865 (2005)
   PUBMED   16138900
  REMARK    GeneRIF: Data suggest that diacylglycerol-activated hmunc13 serves
            as an effector of Rab34, mediating lysosome-Golgi trafficking.
REFERENCE   6  (bases 1 to 6398)
  AUTHORS   Mochida,S., Orita,S., Sakaguchi,G., Sasaki,T. and Takai,Y.
  TITLE     Role of the Doc2 alpha-Munc13-1 interaction in the neurotransmitter
            release process
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 95 (19), 11418-11422 (1998)
   PUBMED   9736751
REFERENCE   7  (bases 1 to 6398)
  AUTHORS   Sakaguchi,G., Orita,S., Naito,A., Maeda,M., Igarashi,H., Sasaki,T.
            and Takai,Y.
  TITLE     A novel brain-specific isoform of beta spectrin: isolation and its
            interaction with Munc13
  JOURNAL   Biochem. Biophys. Res. Commun. 248 (3), 846-851 (1998)
   PUBMED   9704016
REFERENCE   8  (bases 1 to 6398)
  AUTHORS   Song,Y., Ailenberg,M. and Silverman,M.
  TITLE     Cloning of a novel gene in the human kidney homologous to rat
            munc13s: its potential role in diabetic nephropathy
  JOURNAL   Kidney Int. 53 (6), 1689-1695 (1998)
   PUBMED   9607201
REFERENCE   9  (bases 1 to 6398)
  AUTHORS   Orita,S., Naito,A., Sakaguchi,G., Maeda,M., Igarashi,H., Sasaki,T.
            and Takai,Y.
  TITLE     Physical and functional interactions of Doc2 and Munc13 in
            Ca2+-dependent exocytotic machinery
  JOURNAL   J. Biol. Chem. 272 (26), 16081-16084 (1997)
   PUBMED   9195900
REFERENCE   10 (bases 1 to 6398)
  AUTHORS   Betz,A., Okamoto,M., Benseler,F. and Brose,N.
  TITLE     Direct interaction of the rat unc-13 homologue Munc13-1 with the N
            terminus of syntaxin
  JOURNAL   J. Biol. Chem. 272 (4), 2520-2526 (1997)
   PUBMED   8999968
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BP236693.1, AB209998.1 and
            AF020202.1.
            This sequence is a reference standard in the RefSeqGene project.
            On Jul 20, 2006 this sequence version replaced gi:38176153.
            
            Summary: This gene is expressed in the kidney cortical epithelial
            cells and is upregulated by hyperglycemia. The encoded protein
            shares a high level of similarity to the rat homolog, and contains
            3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia
            increases the levels of diacylglycerol, which has been shown to
            induce apoptosis in cells transfected with this gene and thus
            contribute to the renal cell complications of hyperglycemia.
            Studies in other species also indicate a role for this protein in
            the priming step of synaptic vesicle exocytosis. [provided by
            RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF020202.1, AB209998.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025084, ERS025086 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                BP236693.1         1-17
            18-4844             AB209998.1         1-4827
            4845-4845           AF020202.1         4777-4777
            4846-5908           AB209998.1         4829-5891
            5909-6398           AF020202.1         5841-6330
FEATURES             Location/Qualifiers
     source          1..6398
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9p13.3"
     gene            1..6398
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /note="unc-13 homolog B (C. elegans)"
                     /db_xref="GeneID:10497"
                     /db_xref="HGNC:12566"
                     /db_xref="MIM:605836"
     exon            1..314
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       28
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375688301"
     variation       133
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:116072913"
     misc_feature    203..205
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /note="upstream in-frame stop codon"
     variation       251
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:376872459"
     variation       252
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371920951"
     CDS             293..5068
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /note="homolog of rat Munc13 (diacylglycerol-binding);
                     munc13-2"
                     /codon_start=1
                     /product="protein unc-13 homolog B"
                     /protein_id="NP_006368.3"
                     /db_xref="GI:110611226"
                     /db_xref="CCDS:CCDS6579.1"
                     /db_xref="GeneID:10497"
                     /db_xref="HGNC:12566"
                     /db_xref="MIM:605836"
                     /translation="
MSLLCVRVKRAKFQGSPDKFNTYVTLKVQNVKSTTVAVRGDQPSWEQDFMFEISRLDLGLSVEVWNKGLIWDTMVGTVWIALKTIRQSDEEGPGEWSTLEAETLMKDDEICGTRNPTPHKILLDTRFELPFDIPEEEARYWTYKWEQINALGADNEYSSQEESQRKPLPTAAAQCSFEDPDSAVDDRDSDYRSETSNSFPPPYHTASQPNASVHQFPVPVRSPQQLLLQGSSRDSCNDSMQSYDLDYPERRAISPTSSSRYGSSCNVSQGSSQLSELDQYHEQDDDHRETDSIHSCHSSHSLSRDGQAGFGEQEKPLEVTGQAEKEAACEPKEMKEDATTHPPPDLVLQKDHFLGPQESFPEENASSPFTQARAHWIRAVTKVRLQLQEIPDDGDPSLPQWLPEGPAGGLYGIDSMPDLRRKKPLPLVSDLSLVQSRKAGITSAMATRTSLKDEELKSHVYKKTLQALIYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCSECGVKCHEKCQDLLNADCLQRAAEKSCKHGAEDRTQNIIMAMKDRMKIRERNKPEIFEVIRDVFTVNKAAHVQQMKTVKQSVLDGTSKWSAKITITVVCAQGLQAKDKTGSSDPYVTVQVSKTKKRTKTIFGNLNPVWEEKFHFECHNSSDRIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLQISVEIKGEEKVAPYHVQYTCLHENLFHYLTDIQGSGGVRIPEARGDDAWKVYFDETAQEIVDEFAMRYGIESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLITLIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMWHLFAQDMKYALEEHEKDHLCKSADYMNLHFKVKWLHNEYVRDLPVLQGQVPEYPAWFEQFVLQWLDENEDVSLEFLRGALERDKKDGFQQTSEHALFSCSVVDVFTQLNQSFEIIRKLECPDPSILAHYMRRFAKTIGKVLMQYADILSKDFPAYCTKEKLPCILMNNVQQLRVQLEKMFEAMGGKELDLEAADSLKELQVKLNTVLDELSMVFGNSFQVRIDECVRQMADILGQVRGTGNASPDARASAAQDADSVLRPLMDFLDGNLTLFATVCEKTVLKRVLKELWRVVMNTMERMIVLPPLTDQTGTQLIFTAAKELSHLSKLKDHMVREETRNLTPKQCAVLDLALDTIKQYFHAGGNGLKKTFLEKSPDLQSLRYALSLYTQTTDTLIKTFVRSQTTQGSGVDDPVGEVSIQVDLFTHPGTGEHKVTVKVVAANDLKWQTAGMFRPFVEVTMVGPHQSDKKRKFTTKSKSNNWAPKYNETFHFLLGNEEGPESYELQICVKDYCFAREDRVLGLAVMPLRDVTAKGSCACWCPLGRKIHMDETGLTILRILSQRSNDEVAREFVKLKSESRSTEEGS
"
     misc_feature    293..673
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /note="C2 domain first repeat in Munc13 (mammalian
                     uncoordinated) proteins; Region: C2A_Munc13; cd08394"
                     /db_xref="CDD:176040"
     misc_feature    order(359..361,365..367,371..373,383..394,479..481,
                     485..487,503..514)
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176040"
     misc_feature    1724..1873
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /note="Protein kinase C conserved region 1 (C1) .
                     Cysteine-rich zinc binding domain. Some members of this
                     domain family bind phorbol esters and diacylglycerol, some
                     are reported to bind RasGTP. May occur in tandem
                     arrangement. Diacylglycerol (DAG) is a second...; Region:
                     C1; cd00029"
                     /db_xref="CDD:28911"
     misc_feature    order(1724..1726,1763..1765,1772..1774,1814..1816,
                     1823..1825,1838..1840,1847..1849,1871..1873)
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /note="zinc binding sites [ion binding]; other site"
                     /db_xref="CDD:28911"
     misc_feature    order(1745..1747,1754..1759,1784..1804)
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /note="putative DAG/PE binding site; other site"
                     /db_xref="CDD:28911"
     misc_feature    order(1754..1756,1760..1762)
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /note="putative RAS interaction site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:28911"
     misc_feature    2090..2470
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /note="C2 domain second repeat in Munc13 (mammalian
                     uncoordinated) proteins; Region: C2B_Munc13; cd04027"
                     /db_xref="CDD:175993"
     misc_feature    2105..2107
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    order(2138..2140,2156..2158,2294..2296,2300..2302,
                     2351..2353)
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /note="Ca2+ binding site [ion binding]; other site"
                     /db_xref="CDD:175993"
     misc_feature    3041..3358
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /note="Domain of Unknown Function (DUF1041); Region:
                     DUF1041; pfam06292"
                     /db_xref="CDD:148103"
     misc_feature    4085..4507
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /note="Munc13 (mammalian uncoordinated) homology domain;
                     Region: Membr_traf_MHD; pfam10540"
                     /db_xref="CDD:151087"
     misc_feature    4607..4966
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /note="C2 domain third repeat in Munc13 (mammalian
                     uncoordinated) proteins; Region: C2C_Munc13; cd08395"
                     /db_xref="CDD:176041"
     variation       312
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:71521257"
     exon            315..344
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     exon            345..444
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       351
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:200386049"
     variation       407
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140222663"
     exon            445..562
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       456
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377586506"
     variation       464
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:370292765"
     variation       469
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:150345714"
     variation       513
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373656914"
     variation       534
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367834612"
     variation       535
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138015822"
     variation       548
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372260676"
     variation       549
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149086575"
     variation       552
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:143163503"
     variation       556
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202003955"
     exon            563..686
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       600
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140811719"
     variation       606
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201405260"
     variation       616
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372321826"
     variation       621
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:372197543"
     variation       674
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374929028"
     exon            687..760
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       705
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374199987"
     exon            761..818
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       785
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111290100"
     variation       790
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:147253508"
     exon            819..1053
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       829
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:139127549"
     variation       841
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:113747445"
     variation       842
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370449728"
     variation       845
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141451741"
     variation       856
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150856360"
     variation       859
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200169058"
     variation       864
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:202038986"
     variation       866
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139333262"
     variation       893
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146150117"
     variation       899
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140204867"
     variation       906
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138440338"
     variation       923
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373487566"
     variation       953
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:146675814"
     variation       954
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:373846094"
     variation       958
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376032394"
     variation       986
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:148828097"
     variation       990
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370437520"
     variation       1006
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:35199210"
     variation       1043
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369977949"
     exon            1054..1368
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       1074
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368712468"
     variation       1080
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199517826"
     variation       1082
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200673646"
     variation       1104
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374242407"
     variation       1113
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150960215"
     variation       1135
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368657999"
     variation       1154
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372763906"
     variation       1155
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200296975"
     variation       1168
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:140824290"
     variation       1210
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148977415"
     variation       1228
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146057073"
     variation       1241
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369798372"
     variation       1256
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372755412"
     variation       1271
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377203976"
     variation       1278
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138908686"
     variation       1301
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:141476659"
     variation       1303
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372463934"
     variation       1316
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375780668"
     exon            1369..1459
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       1428
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:372189059"
     exon            1460..1506
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       1496
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:147014808"
     exon            1507..1585
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       1513
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:138697622"
     variation       1517
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149350534"
     variation       1520
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:143686793"
     variation       1554
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:75322267"
     variation       1561
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148123786"
     variation       1568
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368072886"
     exon            1586..1660
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       1601
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376500028"
     variation       1626
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375685578"
     variation       1645
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:141942832"
     variation       1651
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368947711"
     exon            1661..1880
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       1669
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:112823171"
     variation       1674
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191978661"
     variation       1684
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138799386"
     variation       1714
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375289848"
     variation       1717
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146131249"
     variation       1721
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367581284"
     variation       1743
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140172954"
     variation       1744
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61732430"
     variation       1765
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146399777"
     variation       1783
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:17849229"
     variation       1788
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371711878"
     variation       1799
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138993835"
     variation       1802
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201925591"
     variation       1805
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374499101"
     variation       1820
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368769067"
     variation       1829
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376050341"
     variation       1848
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:372407646"
     variation       1863
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200739160"
     variation       1870
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:149889294"
     exon            1881..2108
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       1906
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61753426"
     variation       1952
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371483220"
     variation       1953
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200053468"
     variation       1964
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:374967761"
     variation       1965
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142442316"
     variation       1968
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368840993"
     variation       2011
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201328348"
     variation       2019
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:376261047"
     variation       2021
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370039649"
     variation       2022
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373528248"
     variation       2051
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:151329492"
     exon            2109..2250
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       2128
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148645815"
     variation       2164
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144394180"
     variation       2193
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201487370"
     variation       2218
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:55720245"
     variation       2246
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374284179"
     exon            2251..2420
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       2273
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371965791"
     variation       2286
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202163094"
     variation       2290
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141359909"
     variation       2302
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146997010"
     variation       2315
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:61732426"
     variation       2340
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140439964"
     variation       2382
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144007866"
     variation       2395
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:62543222"
     variation       2405
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138199360"
     exon            2421..2536
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       2427
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:142888810"
     variation       2430
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:145062713"
     variation       2478
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376863483"
     variation       2509
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370233463"
     variation       2512
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374464572"
     variation       2513
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368700689"
     exon            2537..2700
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       2561
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:188569841"
     variation       2568
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138938539"
     variation       2580
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:56201405"
     variation       2582
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142152806"
     variation       2584
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372082359"
     variation       2598
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200090482"
     variation       2601
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:367600670"
     variation       2605
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199752726"
     variation       2609
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146391020"
     variation       2635
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371478783"
     variation       2638
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:376656625"
     exon            2701..2851
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       2704
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372457478"
     variation       2710
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148598097"
     variation       2730
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:77118641"
     variation       2760
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:375773142"
     variation       2761
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148771743"
     variation       2788
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3208912"
     variation       2789
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:76917191"
     variation       2812
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200818602"
     variation       2816
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201644197"
     exon            2852..2920
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     exon            2921..3010
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       2927
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:112463632"
     variation       2951
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201421861"
     exon            3011..3139
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       3085
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150519290"
     variation       3121
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139472092"
     variation       3125
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201000360"
     exon            3140..3267
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       3154
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144279601"
     variation       3180
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147799499"
     variation       3201
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139620196"
     variation       3214
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186028846"
     variation       3231
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145265358"
     variation       3241
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:190693606"
     variation       3250
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11541905"
     exon            3268..3353
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       3268
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:375286155"
     variation       3301
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145345718"
     variation       3318
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201180685"
     exon            3354..3480
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       3357
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:17849220"
     variation       3358
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369670031"
     variation       3381
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:149118832"
     variation       3394
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371473723"
     variation       3412
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:143647107"
     variation       3434
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374962956"
     variation       3437
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:151027172"
     variation       3439
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141240425"
     variation       3451
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150684985"
     variation       3459
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145029937"
     variation       3480
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138905819"
     exon            3481..3577
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       3497
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140663072"
     variation       3502
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374094190"
     variation       3535
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150463951"
     variation       3546
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:138319899"
     variation       3573
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149632058"
     exon            3578..3721
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       3580
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:41276043"
     variation       3602
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:202128839"
     variation       3642
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370999495"
     variation       3655
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375113025"
     variation       3663
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:55744473"
     variation       3702
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370745816"
     exon            3722..3799
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       3744
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138607361"
     exon            3800..3877
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       3814
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369168037"
     variation       3820
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142701754"
     variation       3852
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202145715"
     exon            3878..3966
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       3900
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201084997"
     variation       3913
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:147375465"
     variation       3922
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148700946"
     variation       3930
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139605689"
     variation       3931
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111762507"
     variation       3932
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:41315995"
     variation       3944
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377673433"
     variation       3949
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:17849222"
     variation       3950
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370611811"
     variation       3960
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139577182"
     exon            3967..4119
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       3974
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371882456"
     variation       3977
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371128685"
     variation       3978
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199650122"
     variation       3988
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:12339582"
     variation       3996
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199730829"
     variation       4002
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368472596"
     variation       4007
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199656978"
     variation       4026
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201839806"
     variation       4082
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367595308"
     variation       4085
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371863959"
     variation       4090
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:112553459"
     variation       4091
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141208447"
     variation       4092
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200462690"
     variation       4100
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:369860627"
     exon            4120..4243
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       4136
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:143639649"
     variation       4147
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:377073203"
     variation       4150
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:146809876"
     variation       4164
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369779966"
     variation       4186
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372741607"
     variation       4242
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377197435"
     exon            4244..4300
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       4287
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373035054"
     variation       4296
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143717358"
     exon            4301..4381
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       4305
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199676393"
     variation       4307
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148132181"
     variation       4314
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:185611344"
     STS             4328..4436
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /standard_name="MARC_17336-17337:1021394418:1"
                     /db_xref="UniSTS:268276"
     variation       4347
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371802270"
     variation       4364
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369287210"
     exon            4382..4529
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       4384
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369428628"
     variation       4435
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:141044319"
     variation       4445
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372983620"
     variation       4477
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:76220765"
     variation       4478
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:79145949"
     variation       4503
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1056918"
     variation       4504
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1056919"
     variation       4511
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150259776"
     exon            4530..4622
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       4544
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201901981"
     variation       4547
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:372377844"
     variation       4584
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139395290"
     exon            4623..4782
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       4657
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376829580"
     variation       4708
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113306381"
     variation       4740
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201643678"
     exon            4783..6370
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /inference="alignment:Splign:1.39.8"
     variation       4783
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:52810879"
     variation       4805
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142697917"
     variation       4815
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367567567"
     variation       4832
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371689397"
     variation       4852
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200497770"
     variation       4853
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:17849227"
     variation       4854
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147360334"
     variation       4862
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199514152"
     variation       4863
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:137999033"
     variation       4864
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370882921"
     variation       4876
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372431164"
     variation       4896
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:78483173"
     variation       4967
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:143085052"
     variation       4979
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376478024"
     variation       5009
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369613302"
     variation       5025
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149475299"
     variation       5029
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371510721"
     variation       5045
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143964256"
     variation       5046
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148652179"
     variation       5052
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374982765"
     variation       5076
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374039159"
     variation       5099
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200055399"
     variation       5134
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:9695585"
     variation       5240
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:116289735"
     variation       5386
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:151135402"
     variation       5508
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374890923"
     variation       5561
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368511433"
     variation       5638
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140107242"
     variation       5659
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183865384"
     variation       5685
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369862449"
     variation       5709
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188810915"
     variation       5710
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150478655"
     variation       5773
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:202003102"
     variation       5798
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:372187232"
     variation       5835
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201388069"
     variation       5876
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:193293415"
     variation       5878
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:12726"
     variation       5892
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3802423"
     variation       5929
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138572032"
     variation       5953
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:183760747"
     variation       6058
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1802034"
     variation       6070
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:143987160"
     variation       6083
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146847191"
     STS             6127..6347
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /standard_name="A005R04"
                     /db_xref="UniSTS:9957"
     STS             6127..6347
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /standard_name="G20429"
                     /db_xref="UniSTS:9956"
     STS             6146..6288
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
                     /standard_name="D9S2099"
                     /db_xref="UniSTS:74399"
     polyA_signal    6352..6357
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
     polyA_site      6370
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; UNC13; Unc13h2"
ORIGIN      
gtggaatgacgggagggagtcccggcagctcctacctcccagcgatggcgtcgctgtgccgcgcccagtccccagcctgccggccggtactcaccgctacccggagttcgctcagacggtgagatttggggcgggtccgaggcagcggcgggacgctacctgcgaccgggaccatgaggagctgccagacccgtggggccggtaacgagagcagtcgcggcacctgctgagaggaaagagggagcggtccggcgcggctggggcgcggcagaggcttgcccgatcctcggccatgtcactgctctgcgtgcgcgttaaaagggccaaattccagggttcaccagataaatttaacacatatgtgaccctgaaagtacagaatgtgaagagcacaactgtagcagttcgtggtgatcagccttcctgggaacaggatttcatgtttgagattagtcgcctggacctgggtctaagtgtggaggtatggaacaaaggactgatctgggacaccatggtggggactgtgtggattgcgctgaagactattcgtcagtcggatgaggaagggcctggggaatggtccacattagaggcagagacgttaatgaaagacgatgagatctgtggaactagaaacccaactcctcataaaattttgcttgatacaagatttgagttgccttttgatatcccagaggaggaagccagatattggacctacaaatgggagcaaatcaatgccttgggagctgacaatgagtattctagtcaagaagaaagccagaggaagccattgcccactgctgccgcccagtgttcttttgaagaccctgatagtgccgtcgatgaccgagatagtgactatcgcagtgagaccagcaacagcttcccacctccttaccatacagcttcccagcccaacgcttctgtgcaccagttccctgtgccggtgcgatcgccacagcagctgctacttcaaggcagttcccgggactcttgtaatgactctatgcaaagttatgaccttgattatccagagcggcgggctatcagccccaccagcagcagtaggtatggctcctcctgtaatgtgagtcaaggaagctctcagctaagtgaactagaccagtatcacgaacaagatgacgaccatcgggagacggactcgattcattcttgccacagctctcacagcctgtccagagatggccaagcaggttttggagaacaagagaaacccttggaggtgacaggtcaagcagagaaggaggcagcatgtgaacccaaggagatgaaagaagatgccacaacccaccctcccccagatctggtgctgcaaaaagaccacttcctaggtccccaggagagttttcctgaggagaatgcatcttcaccatttacccaagccagagcacattggatccgagcagttaccaaggttcgactccagctgcaggagattccagatgatggtgacccctctctgcctcagtggctcccggaagggccagccggagggctctatggcattgacagcatgccagatttacgcagaaagaagccactgccacttgtcagtgatctgtcactggtccagtctcggaaggcaggaatcacttctgcaatggctacacgcacttctcttaaggacgaagagctgaaatcccacgtgtataagaaaaccctgcaggccttaatctaccccatttcgtgcaccactcctcataactttgaggtctggacggccactaccccaacctactgctatgagtgtgaaggcctgctctggggcattgcccggcagggcatgcgctgcagcgaatgtggagtcaagtgccatgagaagtgccaggatctgctcaatgctgactgcctgcagcgggctgcagaaaagagctgtaaacatggagctgaggaccggacccagaacattatcatggccatgaaggaccgcatgaagatccgagagcgaaataagccagagatctttgaagttatccgggacgtcttcacagtgaacaaagctgcccatgtgcagcagatgaaaacagtgaagcagagtgtactggatggcacctccaaatggtcagccaagatcaccattactgtggtgtgtgcccagggcctacaagccaaggacaaaacaggatccagtgacccttacgtgactgtgcaagtcagcaaaactaagaagcgtaccaagaccatttttggaaacttgaatcctgtttgggaggagaagttccattttgagtgccacaactcctctgaccgcattaaggtgcgtgtatgggatgaggatgatgacatcaagtcaagagtaaagcaacgcctaaagcgagagtctgatgatttccttggccaaaccatcattgaggttcggaccctaagtggcgagatggacgtctggtacaacttggagaagaggacagacaaatcagccgtctcaggggctatccgactacaaatcagtgtggagatcaagggggaggagaaagtagccccataccacgtgcagtatacatgtctccatgagaatcttttccattacctcacagacattcagggcagtggaggagtccgcatccctgaagctcgaggagacgatgcctggaaggtgtactttgatgagacagcccaagaaattgtggatgaatttgccatgcgttatggcattgagtccatatatcaggccatgacgcactttgcatgtttatcatccaagtacatgtgtcctggtgtgccagcagtgatgagcaccttactggccaacatcaacgcctactatgcccacacaactgcctctaccaatgtctctgcatctgatcgctttgcagcctccaactttgggaaagagagatttgtaaaactgctggaccagctacacaactcactgaggatcgacctctctacatacaggaataatttccctgctgggagtcctgaacggcttcaggacttaaaatccacagtggatttgctgaccagcattactttcttcagaatgaaggtacaagaactgcaaagccctccaagagccagccaggtggtaaaggattgtgtgaaggcctgtttgaactccacatatgaatatatcttcaacaactgccacgacttatacagccgccagtaccagctgaagcaggagctacctccagaggaacaagggcccagcattcggaacctggatttctggcccaagctcatcacactcatcgtgtcaatcatagaggaagataagaattcctacacacctgttctgaaccagtttcctcaggagttgaatgtgggaaaagtcagcgcagaagtgatgtggcatttgtttgcccaagacatgaaatatgcattggaggagcatgagaaagaccacctgtgtaaaagtgctgactacatgaacctgcacttcaaggtgaagtggctccacaatgaatacgtgcgggatctgcctgtcctccaggggcaggtgcctgagtacccagcgtggtttgagcagttcgtgctacaatggctggatgagaatgaggatgtatccctggaattcctgcgtggggccctggaacgagataagaaggatggattccagcagacatcagagcatgcactcttttcctgctctgtggtggatgtcttcacacaactcaatcagagctttgagatcatccggaagctggaatgcccagaccccagcatccttgcccactacatgaggaggtttgctaagaccatcgggaaggtgctgatgcagtatgcagacatcttgtcaaaggacttcccagcctattgcacaaaggagaaactgccctgcatcctgatgaacaacgtgcagcaactgagggtccagctggagaaaatgtttgaggccatgggaggcaaggagctggaccttgaagctgcagacagtctgaaggagctgcaggtgaaactgaatacggttctggatgagctcagcatggtgtttggaaacagtttccaggtacggattgatgagtgtgttcgacaaatggccgacatcctgggccaggttcggggcacagggaatgcatctccagacgccagggcctcagcggctcaggatgcagatagcgtactccggcctctcatggacttcctggatggcaacctcaccctctttgccactgtgtgtgagaagacggttctgaagcgtgtactgaaggagctctggcgcgtggtgatgaacacaatggagaggatgattgttctgcccccactcactgaccagacgggcacccagctgatcttcactgctgccaaggagctgagccatctttccaaactcaaggatcacatggtacgagaggaaacacggaatctcactccaaagcagtgtgcagtccttgacctcgccctggacaccatcaagcaatacttccatgcaggaggcaatgggctgaagaaaaccttcctggagaagagcccagatctgcagtctctacgctatgccctgtctctgtacacacagactactgacactctcatcaagacctttgtgcgctcgcagaccacccaagggtctggtgtggacgatcctgtgggagaagtctctattcaggtggacttgtttacacaccctggtactggggagcacaaggtcacagtgaaagtggtggctgccaatgacctcaagtggcagacagcgggtatgttccggcctttcgtggaggtgactatggttggcccacaccaaagtgataagaagaggaagttcacaaccaaatccaaaagcaacaactgggcccccaagtacaatgagacattccacttcctcctgggaaatgaggaggggcccgagtcctatgagttgcagatatgcgtgaaggattactgctttgcccgggaagatcgcgtgctagggctggctgtgatgcctctgagggatgtcacagccaagggcagctgtgcctgctggtgccccttgggccggaagatccatatggatgagacaggcctgaccattctccggattttatctcagaggagcaatgacgaggtggcccgagaatttgtgaaactcaaatcagagtctcgttccacggaggaggggagctgaacaccttcgactcctgtgccaatcaggcagcagcaatttcacaaatcagggccagtgggagttagctgtgtaaccggcttagggtctttgcagtcaagaggctgaccccttcagttaaagatatttaaggaaaaatttggggtggtgataatatggcttttcacagaaagggtcatgaagccctggcccaacaggactgtggtactaggggctgggatgtggggttaccacatggagagattttccattaagagagaaggacaaacatttctgagagtgtcagccattcttggtagacacctctccactcctcatcccacctctacccatctccatgccacaccttatccagttagacacatacataccaatcattagaagaacaagtttagaaggtgtggaacttgtgcctggctggctgggtagtcagctgagcctgttgctgagcccggtggtctggattggagtatggccagggcaggagtacacagaatagaatttagactgtcccttgagtagaatccactgattttctgtggctccagtgagaacaaggctttgaaactgaacaagataacttctagaaatgaactgtactaatccctttccccagattgtatcatgagtagaatcaggttcacgtggtgcttcaaagccctgagaagaatatttctttggaccccaggcactaggggccacctgcctgggagtctccctgcctcactcctctaggcaggggagtgatgcttcaggacgtgacaggctgttctaacatgtgtctacctgagggctagttgaaggatccaggagtattttcttcttgggtgggccctgaacaaagccaaaaattgtagaaaccagtctagaaaaagtcctgctcatctgtggccactgccttctagccgtcctccaccttgcagaaagaatctagcctttggtctctctctctctcatcggggtcatttgctattcccctctgatattcaaccctatagaaggagcctggactctgatccctctgtacaggctggatggaaggggccctccacacttcctgggaggtcagagacaaactgtttcagagagtcagatggacttcccaagacttgttgagagatgtgacatggttcttggatttcctctgtagcagcctcctggacttcctgaggactcgacattgtccacagatgtactggccattacatgaaacaagaaaccaagcatctttgctgttgttaattattatatgtgccattgttacaggagattataggctagtctgtaataaattatcttatagcaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:10497 -> Molecular function: GO:0004871 [signal transducer activity] evidence: TAS
            GeneID:10497 -> Molecular function: GO:0004872 [receptor activity] evidence: TAS
            GeneID:10497 -> Molecular function: GO:0019992 [diacylglycerol binding] evidence: IEA
            GeneID:10497 -> Molecular function: GO:0046872 [metal ion binding] evidence: IEA
            GeneID:10497 -> Biological process: GO:0006917 [induction of apoptosis] evidence: TAS
            GeneID:10497 -> Biological process: GO:0007165 [signal transduction] evidence: TAS
            GeneID:10497 -> Biological process: GO:0007528 [neuromuscular junction development] evidence: IEA
            GeneID:10497 -> Biological process: GO:0007588 [excretion] evidence: TAS
            GeneID:10497 -> Biological process: GO:0016081 [synaptic vesicle docking involved in exocytosis] evidence: IEA
            GeneID:10497 -> Biological process: GO:0016082 [synaptic vesicle priming] evidence: IEA
            GeneID:10497 -> Biological process: GO:0035249 [synaptic transmission, glutamatergic] evidence: IEA
            GeneID:10497 -> Biological process: GO:0035556 [intracellular signal transduction] evidence: IEA
            GeneID:10497 -> Biological process: GO:0048172 [regulation of short-term neuronal synaptic plasticity] evidence: IEA
            GeneID:10497 -> Biological process: GO:0060384 [innervation] evidence: IEA
            GeneID:10497 -> Cellular component: GO:0005737 [cytoplasm] evidence: TAS
            GeneID:10497 -> Cellular component: GO:0005794 [Golgi apparatus] evidence: TAS
            GeneID:10497 -> Cellular component: GO:0005886 [plasma membrane] evidence: IEA
            GeneID:10497 -> Cellular component: GO:0030054 [cell junction] evidence: IEA
            GeneID:10497 -> Cellular component: GO:0031594 [neuromuscular junction] evidence: IEA

by @meso_cacase at DBCLS
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