GGRNA Home | Help | Advanced search

2024-03-29 07:34:43, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_006325               1087 bp    mRNA    linear   PRI 07-JUL-2013
DEFINITION  Homo sapiens RAN, member RAS oncogene family (RAN), mRNA.
ACCESSION   NM_006325
VERSION     NM_006325.3  GI:219879807
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1087)
  AUTHORS   Yuen,H.F., Gunasekharan,V.K., Chan,K.K., Zhang,S.D.,
            Platt-Higgins,A., Gately,K., O'Byrne,K., Fennell,D.A.,
            Johnston,P.G., Rudland,P.S. and El-Tanani,M.
  TITLE     RanGTPase: a candidate for Myc-mediated cancer progression
  JOURNAL   J. Natl. Cancer Inst. 105 (7), 475-488 (2013)
   PUBMED   23468463
  REMARK    GeneRIF: Results suggest that Ran is required for and is a
            potential therapeutic target of Myc-driven cancer progression in
            both breast and lung cancers.
REFERENCE   2  (bases 1 to 1087)
  AUTHORS   Nagai,M. and Yoneda,Y.
  TITLE     Downregulation of the small GTPase ras-related nuclear protein
            accelerates cellular ageing
  JOURNAL   Biochim. Biophys. Acta 1830 (3), 2813-2819 (2013)
   PUBMED   23160023
  REMARK    GeneRIF: Reduction in Ran levels causes cytoplasmic decrease and
            nuclear accumulation of importin alpha leading to cellular
            senescence in normal cells.
REFERENCE   3  (bases 1 to 1087)
  AUTHORS   Mastroeni,D., Chouliaras,L., Grover,A., Liang,W.S., Hauns,K.,
            Rogers,J. and Coleman,P.D.
  TITLE     Reduced RAN expression and disrupted transport between cytoplasm
            and nucleus; a key event in Alzheimer's disease pathophysiology
  JOURNAL   PLoS ONE 8 (1), E53349 (2013)
   PUBMED   23308199
  REMARK    GeneRIF: Reduced RAN expression and disrupted transport between
            cytoplasm and nucleus are the key events in Alzheimer's disease
            pathophysiology.
REFERENCE   4  (bases 1 to 1087)
  AUTHORS   Milano,S.K., Kwon,W., Pereira,R., Antonyak,M.A. and Cerione,R.A.
  TITLE     Characterization of a novel activated Ran GTPase mutant and its
            ability to induce cellular transformation
  JOURNAL   J. Biol. Chem. 287 (30), 24955-24966 (2012)
   PUBMED   22679017
  REMARK    GeneRIF: a novel connection between the hyper-activation of the
            small GTPase Ran and the matricellular protein SMOC-2 that has
            important consequences for oncogenic transformation.
REFERENCE   5  (bases 1 to 1087)
  AUTHORS   Atabakhsh,E. and Schild-Poulter,C.
  TITLE     RanBPM is an inhibitor of ERK signaling
  JOURNAL   PLoS ONE 7 (10), E47803 (2012)
   PUBMED   23118896
  REMARK    GeneRIF: RanBPM loss of expression results in constitutive
            activation of the ERK pathway and promotes cellular events leading
            to cellular transformation and tumorigenesis.
REFERENCE   6  (bases 1 to 1087)
  AUTHORS   Yokoyama,N., Hayashi,N., Seki,T., Pante,N., Ohba,T., Nishii,K.,
            Kuma,K., Hayashida,T., Miyata,T., Aebi,U. et al.
  TITLE     A giant nucleopore protein that binds Ran/TC4
  JOURNAL   Nature 376 (6536), 184-188 (1995)
   PUBMED   7603572
REFERENCE   7  (bases 1 to 1087)
  AUTHORS   Dawson,S.J. and White,L.A.
  TITLE     Treatment of Haemophilus aphrophilus endocarditis with
            ciprofloxacin
  JOURNAL   J. Infect. 24 (3), 317-320 (1992)
   PUBMED   1602151
REFERENCE   8  (bases 1 to 1087)
  AUTHORS   Bischoff,F.R. and Ponstingl,H.
  TITLE     Mitotic regulator protein RCC1 is complexed with a nuclear
            ras-related polypeptide
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 88 (23), 10830-10834 (1991)
   PUBMED   1961752
REFERENCE   9  (bases 1 to 1087)
  AUTHORS   Matsumoto,T. and Beach,D.
  TITLE     Premature initiation of mitosis in yeast lacking RCC1 or an
            interacting GTPase
  JOURNAL   Cell 66 (2), 347-360 (1991)
   PUBMED   1855255
REFERENCE   10 (bases 1 to 1087)
  AUTHORS   Drivas,G.T., Shih,A., Coutavas,E., Rush,M.G. and D'Eustachio,P.
  TITLE     Characterization of four novel ras-like genes expressed in a human
            teratocarcinoma cell line
  JOURNAL   Mol. Cell. Biol. 10 (4), 1793-1798 (1990)
   PUBMED   2108320
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC000852.1 and BC004272.1.
            On Jan 9, 2009 this sequence version replaced gi:6042206.
            
            Summary: RAN (ras-related nuclear protein) is a small GTP binding
            protein belonging to the RAS superfamily that is essential for the
            translocation of RNA and proteins through the nuclear pore complex.
            The RAN protein is also involved in control of DNA synthesis and
            cell cycle progression. Nuclear localization of RAN requires the
            presence of regulator of chromosome condensation 1 (RCC1).
            Mutations in RAN disrupt DNA synthesis. Because of its many
            functions, it is likely that RAN interacts with several other
            proteins. RAN regulates formation and organization of the
            microtubule network independently of its role in the
            nucleus-cytosol exchange of macromolecules. RAN could be a key
            signaling molecule regulating microtubule polymerization during
            mitosis. RCC1 generates a high local concentration of RAN-GTP
            around chromatin which, in turn, induces the local nucleation of
            microtubules.  RAN is an androgen receptor (AR) coactivator that
            binds differentially with different lengths of polyglutamine within
            the androgen receptor. Polyglutamine repeat expansion in the AR is
            linked to Kennedy's disease (X-linked spinal and bulbar muscular
            atrophy). RAN coactivation of the AR diminishes with polyglutamine
            expansion within the AR, and this weak coactivation may lead to
            partial androgen insensitivity during the development of Kennedy's
            disease. [provided by RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC051908.2, AF054183.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025082 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1068              BC000852.1         1-1068
            1069-1087           BC004272.1         1032-1050
FEATURES             Location/Qualifiers
     source          1..1087
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q24.3"
     gene            1..1087
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /note="RAN, member RAS oncogene family"
                     /db_xref="GeneID:5901"
                     /db_xref="HGNC:9846"
                     /db_xref="HPRD:03109"
                     /db_xref="MIM:601179"
     exon            1..55
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /inference="alignment:Splign:1.39.8"
     variation       22
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147215193"
     variation       29
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11546491"
     variation       46
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1127636"
     exon            56..101
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /inference="alignment:Splign:1.39.8"
     CDS             66..716
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /note="guanosine triphosphatase Ran; RanGTPase;
                     OK/SW-cl.81; member RAS oncogene family; GTPase Ran;
                     ras-like protein TC4; ras-related nuclear protein;
                     androgen receptor-associated protein 24"
                     /codon_start=1
                     /product="GTP-binding nuclear protein Ran"
                     /protein_id="NP_006316.1"
                     /db_xref="GI:5453555"
                     /db_xref="CCDS:CCDS9271.1"
                     /db_xref="GeneID:5901"
                     /db_xref="HGNC:9846"
                     /db_xref="HPRD:03109"
                     /db_xref="MIM:601179"
                     /translation="
MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
"
     misc_feature    66..713
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /note="GTP-binding nuclear protein Ran; Provisional;
                     Region: PTZ00132"
                     /db_xref="CDD:240284"
     misc_feature    69..71
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N-acetylalanine; propagated from
                     UniProtKB/Swiss-Prot (P62826.3); acetylation site"
     misc_feature    96..593
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /note="Ras-related nuclear proteins (Ran)/TC4 family of
                     small GTPases; Region: Ran; cd00877"
                     /db_xref="CDD:206643"
     misc_feature    114..137
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /note="G1 box; other site"
                     /db_xref="CDD:206643"
     misc_feature    order(117..119,180..182,186..188,192..197,270..275,
                     288..290,300..302,345..353,447..449,453..455)
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /note="GAP interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:206643"
     misc_feature    order(120..122,264..266,276..284,291..293,345..365,
                     369..374,381..386,393..395,465..467,474..476,483..485)
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /note="GEF interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:206643"
     misc_feature    order(123..125,129..140,429..431,438..440,516..521)
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206643"
     misc_feature    order(150..152,159..167,216..221,228..233,405..407,
                     480..485,492..494,537..539,564..572)
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /note="Co-activator interaction site; other site"
                     /db_xref="CDD:206643"
     misc_feature    order(156..170,183..209)
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206643"
     misc_feature    order(174..176,255..257,285..296,300..302,306..311,
                     342..344,393..398,432..434,438..443,447..449,459..461,
                     465..467,492..494,519..524)
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /note="Exportin interaction site in Cse1p/Kap60p/RanGTP
                     complex [polypeptide binding]; other site"
                     /db_xref="CDD:206643"
     misc_feature    189..191
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /note="G2 box; other site"
                     /db_xref="CDD:206643"
     misc_feature    order(204..206,255..257,285..287,294..299,306..311,
                     393..395,465..467,483..488,522..533,537..539)
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /note="Importin (transport factor) interaction site
                     [polypeptide binding]; other site"
                     /db_xref="CDD:206643"
     misc_feature    243..245
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N6-acetyllysine; propagated from
                     UniProtKB/Swiss-Prot (P62826.3); acetylation site"
     misc_feature    258..269
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /note="G3 box; other site"
                     /db_xref="CDD:206643"
     misc_feature    264..320
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206643"
     misc_feature    276..278
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N6-acetyllysine, alternate; propagated from
                     UniProtKB/Swiss-Prot (P62826.3); acetylation site"
     misc_feature    360..362
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N6-acetyllysine; propagated from
                     UniProtKB/Swiss-Prot (P62826.3); acetylation site"
     misc_feature    429..440
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /note="G4 box; other site"
                     /db_xref="CDD:206643"
     misc_feature    468..470
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P62826.3); phosphorylation site"
     misc_feature    504..506
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    504..506
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    513..521
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /note="G5 box; other site"
                     /db_xref="CDD:206643"
     misc_feature    528..530
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    540..542
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N6-acetyllysine; propagated from
                     UniProtKB/Swiss-Prot (P62826.3); acetylation site"
     variation       69
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11546489"
     exon            102..186
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /inference="alignment:Splign:1.39.8"
     STS             106..248
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /standard_name="GDB:451538"
                     /db_xref="UniSTS:157307"
     variation       108
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142740158"
     variation       117
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200416921"
     variation       140
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199512241"
     variation       143
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:116832702"
     variation       160
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11546492"
     variation       185
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:116685516"
     exon            187..312
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /inference="alignment:Splign:1.39.8"
     variation       191
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:199644788"
     variation       230
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145207608"
     variation       233
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114011062"
     variation       245
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150576123"
     variation       254
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2293512"
     variation       263
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:201353570"
     variation       296
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200748775"
     exon            313..500
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /inference="alignment:Splign:1.39.8"
     variation       314
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:139618829"
     variation       326
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149783374"
     variation       335
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146783236"
     variation       347
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1802283"
     variation       377
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11546493"
     variation       408
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200176335"
     STS             459..673
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /standard_name="STS-M31469"
                     /db_xref="UniSTS:4649"
     exon            501..671
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /inference="alignment:Splign:1.39.8"
     variation       506
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373832485"
     variation       627
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201928609"
     variation       629
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199809948"
     variation       662
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371816272"
     exon            672..1071
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /inference="alignment:Splign:1.39.8"
     variation       866
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:15220"
     variation       868
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145363958"
     variation       882..883
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:373935763"
     variation       887
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:113688889"
     STS             923..1018
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /standard_name="WI-16177"
                     /db_xref="UniSTS:69938"
     variation       960
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3803012"
     variation       969
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1802299"
     variation       982
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1045515"
     variation       985
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149187550"
     polyA_signal    1046..1051
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
     polyA_site      1071
                     /gene="RAN"
                     /gene_synonym="ARA24; Gsp1; TC4"
ORIGIN      
cgcttccgccatctttccagcctcagtcggacgggcgcggagacgcttctggaaggaacgccgcgatggctgcgcagggagagccccaggtccagttcaaacttgtattggttggtgatggtggtactggaaaaacgaccttcgtgaaacgtcatttgactggtgaatttgagaagaagtatgtagccaccttgggtgttgaggttcatcccctagtgttccacaccaacagaggacctattaagttcaatgtatgggacacagccggccaggagaaattcggtggactgagagatggctattatatccaagcccagtgtgccatcataatgtttgatgtaacatcgagagttacttacaagaatgtgcctaactggcatagagatctggtacgagtgtgtgaaaacatccccattgtgttgtgtggcaacaaagtggatattaaggacaggaaagtgaaggcgaaatccattgtcttccaccgaaagaagaatcttcagtactacgacatttctgccaaaagtaactacaactttgaaaagcccttcctctggcttgctaggaagctcattggagaccctaacttggaatttgttgccatgcctgctctcgccccaccagaagttgtcatggacccagctttggcagcacagtatgagcacgacttagaggttgctcagacaactgctctcccggatgaggatgatgacctgtgagaatgaagctggagcccagcgtcagaagtctagttttataggcagctgtcctgtgatgtcagcggtgcagcgtgtgtgccacctcattattatctagctaagcggaacatgtgcttcatctgtgggatgctgaaggagatgagtgggcttcggagtgaatgtggcagtttaaaaaataacttcattgtttggacctgcatatttagctgttttggaacgcagttgattccttgagtttcatatataagactgctgcagtcacatcacaatattcagtggtgaaatcttgtttgttactgtcattcccattccttttcgtttagaatcagaataaagttgtatttcaaatatctaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:5901 -> Molecular function: GO:0003682 [chromatin binding] evidence: TAS
            GeneID:5901 -> Molecular function: GO:0003713 [transcription coactivator activity] evidence: NAS
            GeneID:5901 -> Molecular function: GO:0003924 [GTPase activity] evidence: TAS
            GeneID:5901 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:5901 -> Molecular function: GO:0005525 [GTP binding] evidence: IDA
            GeneID:5901 -> Molecular function: GO:0050681 [androgen receptor binding] evidence: NAS
            GeneID:5901 -> Biological process: GO:0006259 [DNA metabolic process] evidence: TAS
            GeneID:5901 -> Biological process: GO:0006405 [RNA export from nucleus] evidence: NAS
            GeneID:5901 -> Biological process: GO:0006606 [protein import into nucleus] evidence: IEA
            GeneID:5901 -> Biological process: GO:0006611 [protein export from nucleus] evidence: IDA
            GeneID:5901 -> Biological process: GO:0006611 [protein export from nucleus] evidence: NAS
            GeneID:5901 -> Biological process: GO:0007052 [mitotic spindle organization] evidence: TAS
            GeneID:5901 -> Biological process: GO:0007067 [mitosis] evidence: TAS
            GeneID:5901 -> Biological process: GO:0007165 [signal transduction] evidence: TAS
            GeneID:5901 -> Biological process: GO:0007264 [small GTPase mediated signal transduction] evidence: IEA
            GeneID:5901 -> Biological process: GO:0010467 [gene expression] evidence: TAS
            GeneID:5901 -> Biological process: GO:0016032 [viral process] evidence: TAS
            GeneID:5901 -> Biological process: GO:0019058 [viral infectious cycle] evidence: TAS
            GeneID:5901 -> Biological process: GO:0030036 [actin cytoskeleton organization] evidence: IEA
            GeneID:5901 -> Biological process: GO:0030521 [androgen receptor signaling pathway] evidence: NAS
            GeneID:5901 -> Biological process: GO:0032092 [positive regulation of protein binding] evidence: IDA
            GeneID:5901 -> Biological process: GO:0034629 [cellular protein complex localization] evidence: IEA
            GeneID:5901 -> Biological process: GO:0044281 [small molecule metabolic process] evidence: TAS
            GeneID:5901 -> Biological process: GO:0045893 [positive regulation of transcription, DNA-dependent] evidence: NAS
            GeneID:5901 -> Biological process: GO:0051301 [cell division] evidence: IEA
            GeneID:5901 -> Biological process: GO:0075733 [intracellular transport of viral material] evidence: TAS
            GeneID:5901 -> Cellular component: GO:0000785 [chromatin] evidence: IDA
            GeneID:5901 -> Cellular component: GO:0005643 [nuclear pore] evidence: NAS
            GeneID:5901 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
            GeneID:5901 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
            GeneID:5901 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:5901 -> Cellular component: GO:0042470 [melanosome] evidence: IEA
ANNOTATIONS from NCBI Entrez Gene (20130726):
            NP_006316 -> EC 3.6.5.1
            NP_006316 -> EC 3.6.5.2
            NP_006316 -> EC 3.6.5.3
            NP_006316 -> EC 3.6.5.4

by @meso_cacase at DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.