2024-04-23 18:38:04, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_006290 4705 bp mRNA linear PRI 07-JUL-2013 DEFINITION Homo sapiens tumor necrosis factor, alpha-induced protein 3 (TNFAIP3), transcript variant 3, mRNA. ACCESSION NM_006290 VERSION NM_006290.3 GI:395393993 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 4705) AUTHORS Li,H., Liu,Q., Hou,S., Du,L., Zhou,Q., Zhou,Y., Kijlstra,A., Li,Z. and Yang,P. TITLE TNFAIP3 gene polymorphisms confer risk for Behcet's disease in a Chinese Han population JOURNAL Hum. Genet. 132 (3), 293-300 (2013) PUBMED 23161053 REMARK GeneRIF: This study identified one strong risk SNP rs9494885 and two weak risk SNPs rs10499194 and rs7753873 of TNFAIP3 in Chinese Han Behcet disease (BD) patients. REFERENCE 2 (bases 1 to 4705) AUTHORS Yu B, Barbalic M, Brautbar A, Nambi V, Hoogeveen RC, Tang W, Mosley TH, Rotter JI, deFilippi CR, O'Donnell CJ, Kathiresan S, Rice K, Heckbert SR, Ballantyne CM, Psaty BM and Boerwinkle E. CONSRTM CARDIoGRAM Consortium TITLE Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies JOURNAL Circ Cardiovasc Genet 6 (1), 82-88 (2013) PUBMED 23247143 REFERENCE 3 (bases 1 to 4705) AUTHORS Yang,W., Tang,H., Zhang,Y., Tang,X., Zhang,J., Sun,L., Yang,J., Cui,Y., Zhang,L., Hirankarn,N., Cheng,H., Pan,H.F., Gao,J., Lee,T.L., Sheng,Y., Lau,C.S., Li,Y., Chan,T.M., Yin,X., Ying,D., Lu,Q., Leung,A.M., Zuo,X., Chen,X., Tong,K.L., Zhou,F., Diao,Q., Tse,N.K., Xie,H., Mok,C.C., Hao,F., Wong,S.N., Shi,B., Lee,K.W., Hui,Y., Ho,M.H., Liang,B., Lee,P.P., Cui,H., Guo,Q., Chung,B.H., Pu,X., Liu,Q., Zhang,X., Zhang,C., Chong,C.Y., Fang,H., Wong,R.W., Sun,Y., Mok,M.Y., Li,X.P., Avihingsanon,Y., Zhai,Z., Rianthavorn,P., Deekajorndej,T., Suphapeetiporn,K., Gao,F., Shotelersuk,V., Kang,X., Ying,S.K., Zhang,L., Wong,W.H., Zhu,D., Fung,S.K., Zeng,F., Lai,W.M., Wong,C.M., Ng,I.O., Garcia-Barcelo,M.M., Cherny,S.S., Shen,N., Tam,P.K., Sham,P.C., Ye,D.Q., Yang,S., Zhang,X. and Lau,Y.L. TITLE Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians JOURNAL Am. J. Hum. Genet. 92 (1), 41-51 (2013) PUBMED 23273568 REFERENCE 4 (bases 1 to 4705) AUTHORS Kulathu,Y., Garcia,F.J., Mevissen,T.E., Busch,M., Arnaudo,N., Carroll,K.S., Barford,D. and Komander,D. TITLE Regulation of A20 and other OTU deubiquitinases by reversible oxidation JOURNAL Nat Commun 4, 1569 (2013) PUBMED 23463012 REMARK GeneRIF: The reversible form of A20 oxidation is a cysteine sulphenic acid intermediate, which is stabilised by the architecture of the catalytic centre. REFERENCE 5 (bases 1 to 4705) AUTHORS Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN, Andersen V, Andrews JM, Baidoo L, Balschun T, Bampton PA, Bitton A, Boucher G, Brand S, Buning C, Cohain A, Cichon S, D'Amato M, De Jong D, Devaney KL, Dubinsky M, Edwards C, Ellinghaus D, Ferguson LR, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas J, Haritunians T, Hart A, Hawkey C, Hedl M, Hu X, Karlsen TH, Kupcinskas L, Kugathasan S, Latiano A, Laukens D, Lawrance IC, Lees CW, Louis E, Mahy G, Mansfield J, Morgan AR, Mowat C, Newman W, Palmieri O, Ponsioen CY, Potocnik U, Prescott NJ, Regueiro M, Rotter JI, Russell RK, Sanderson JD, Sans M, Satsangi J, Schreiber S, Simms LA, Sventoraityte J, Targan SR, Taylor KD, Tremelling M, Verspaget HW, De Vos M, Wijmenga C, Wilson DC, Winkelmann J, Xavier RJ, Zeissig S, Zhang B, Zhang CK, Zhao H, Silverberg MS, Annese V, Hakonarson H, Brant SR, Radford-Smith G, Mathew CG, Rioux JD, Schadt EE, Daly MJ, Franke A, Parkes M, Vermeire S, Barrett JC and Cho JH. CONSRTM International IBD Genetics Consortium (IIBDGC) TITLE Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease JOURNAL Nature 491 (7422), 119-124 (2012) PUBMED 23128233 REFERENCE 6 (bases 1 to 4705) AUTHORS Vincenz,C. and Dixit,V.M. TITLE 14-3-3 proteins associate with A20 in an isoform-specific manner and function both as chaperone and adapter molecules JOURNAL J. Biol. Chem. 271 (33), 20029-20034 (1996) PUBMED 8702721 REFERENCE 7 (bases 1 to 4705) AUTHORS Cooper,J.T., Stroka,D.M., Brostjan,C., Palmetshofer,A., Bach,F.H. and Ferran,C. TITLE A20 blocks endothelial cell activation through a NF-kappaB-dependent mechanism JOURNAL J. Biol. Chem. 271 (30), 18068-18073 (1996) PUBMED 8663499 REFERENCE 8 (bases 1 to 4705) AUTHORS Song,H.Y., Rothe,M. and Goeddel,D.V. TITLE The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation JOURNAL Proc. Natl. Acad. Sci. U.S.A. 93 (13), 6721-6725 (1996) PUBMED 8692885 REFERENCE 9 (bases 1 to 4705) AUTHORS Opipari,A.W. Jr., Boguski,M.S. and Dixit,V.M. TITLE The A20 cDNA induced by tumor necrosis factor alpha encodes a novel type of zinc finger protein JOURNAL J. Biol. Chem. 265 (25), 14705-14708 (1990) PUBMED 2118515 REFERENCE 10 (bases 1 to 4705) AUTHORS Dixit,V.M., Green,S., Sarma,V., Holzman,L.B., Wolf,F.W., O'Rourke,K., Ward,P.A., Prochownik,E.V. and Marks,R.M. TITLE Tumor necrosis factor-alpha induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxin JOURNAL J. Biol. Chem. 265 (5), 2973-2978 (1990) PUBMED 2406243 COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY085289.1, M59465.1 and CB528739.1. This sequence is a reference standard in the RefSeqGene project. On Jul 13, 2012 this sequence version replaced gi:26051241. Summary: This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012]. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All three variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M59465.1, BC113871.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025081, ERS025082 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-256 HY085289.1 4-259 257-4424 M59465.1 1-4168 4425-4705 CB528739.1 1-281 c FEATURES Location/Qualifiers source 1..4705 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="6" /map="6q23" gene 1..4705 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /note="tumor necrosis factor, alpha-induced protein 3" /db_xref="GeneID:7128" /db_xref="HGNC:11896" /db_xref="HPRD:01857" /db_xref="MIM:191163" exon 1..307 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /inference="alignment:Splign:1.39.8" STS 30..115 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /standard_name="PMC135646P2" /db_xref="UniSTS:270766" exon 308..617 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /inference="alignment:Splign:1.39.8" variation 309 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="g" /replace="t" /db_xref="dbSNP:199763604" variation 318 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:369927129" CDS 323..2695 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /EC_number="3.4.19.12" /note="tumor necrosis factor inducible protein A20; zinc finger protein A20; TNF alpha-induced protein 3; OTU domain-containing protein 7C; putative DNA-binding protein A20" /codon_start=1 /product="tumor necrosis factor alpha-induced protein 3" /protein_id="NP_006281.1" /db_xref="GI:5454132" /db_xref="CCDS:CCDS5187.1" /db_xref="GeneID:7128" /db_xref="HGNC:11896" /db_xref="HPRD:01857" /db_xref="MIM:191163" /translation="
MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTPMARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPKLNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRSPGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCFKRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGDRTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGRECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARASCKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCNECFQFKQMYG
" mat_peptide 323..1639 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /product="A20p50" /experiment="experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P21580.1)" misc_feature 494..1222 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /experiment="experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P21580.1); Region: TRAF-binding" misc_feature 614..1093 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /note="OTU-like cysteine protease; Region: OTU; pfam02338" /db_xref="CDD:202209" misc_feature 791..799 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P21580.1); Region: Interaction with ubiquitin (Probable)" misc_feature 890..898 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P21580.1); Region: Interaction with ubiquitin (Probable)" misc_feature 992..1003 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P21580.1); Region: Interaction with ubiquitin (Probable)" misc_feature 1178..1390 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /experiment="experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P21580.1); Region: 2 X approximate repeats" misc_feature 1427..2647 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P21580.1); Region: Interaction with TNIP1 (By similarity)" misc_feature 1472..1549 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /note="A20-like zinc fingers; Region: ZnF_A20; smart00259" /db_xref="CDD:128555" misc_feature 1478..1681 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /experiment="experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P21580.1); Region: Interaction with RIPK1" misc_feature 1637..1642 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /experiment="experimental evidence, no additional details recorded" /note="Cleavage, by MALT1; propagated from UniProtKB/Swiss-Prot (P21580.1); cleavage site" mat_peptide 1640..2692 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /product="A20p37" /experiment="experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P21580.1)" misc_feature 1697..1699 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /experiment="experimental evidence, no additional details recorded" /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot (P21580.1); phosphorylation site" misc_feature 1745..1822 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /note="A20-like zinc fingers; Region: ZnF_A20; smart00259" /db_xref="CDD:128555" misc_feature 2045..2047 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" misc_feature 2132..2209 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /note="A20-like zinc fingers; Region: ZnF_A20; smart00259" /db_xref="CDD:128555" misc_feature 2135..2287 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P21580.1); Region: Required for proteosomal degradation of UBE2N and UBE2D3, TRAF6 deubiquitination, and TAX1BP1 interaction with UBE2N (By similarity)" misc_feature 2138..2692 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P21580.1); Region: Sufficient for inhibitory activity of TNF-induced NF-kappa-B activity (By similarity)" misc_feature 2267..2269 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /experiment="experimental evidence, no additional details recorded" /note="phosphorylation site" misc_feature 2282..2359 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /note="A20-like zinc fingers; Region: ZnF_A20; smart00259" /db_xref="CDD:128555" misc_feature 2411..2692 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /experiment="experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P21580.1); Region: Required for lysosomal localization and for TRAF2 lysosomal degradation" misc_feature 2459..2536 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /note="A20-like zinc finger; Region: zf-A20; cl11604" /db_xref="CDD:209366" misc_feature 2597..2674 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /note="A20-like zinc fingers; Region: ZnF_A20; smart00259" /db_xref="CDD:128555" variation 356 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:138988092" variation 384 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:149162594" variation 385 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="t" /db_xref="dbSNP:183283680" variation 387 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:199876928" variation 407 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="t" /db_xref="dbSNP:376163335" variation 447 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="g" /db_xref="dbSNP:370854824" variation 530 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:375335818" variation 535 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:143308022" variation 559 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="g" /db_xref="dbSNP:148028402" variation 570 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:112229105" variation 604 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:142122102" variation 613 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:376435384" variation 616 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:146004919" exon 618..808 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /inference="alignment:Splign:1.39.8" variation 622 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:368218194" variation 627 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:146534657" variation 644 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:376205580" variation 665 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:150717698" variation 688 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="g" /db_xref="dbSNP:139060168" variation 696 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:5029941" variation 702 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="g" /replace="t" /db_xref="dbSNP:2230926" variation 708 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:183020993" STS 711..791 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /standard_name="PMC152246P3" /db_xref="UniSTS:271205" variation 712 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="g" /replace="t" /db_xref="dbSNP:202005030" variation 728 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:200740561" variation 760 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:1065077" variation 787 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:140424499" variation 807 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:144788826" exon 809..956 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /inference="alignment:Splign:1.39.8" variation 831 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:373331557" variation 870 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:375378882" variation 873 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:147932545" variation 874 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:370174617" variation 880..881 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="" /replace="t" /db_xref="dbSNP:34935799" variation 941 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="c" /db_xref="dbSNP:141807543" exon 957..1127 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /inference="alignment:Splign:1.39.8" variation 963 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="g" /replace="t" /db_xref="dbSNP:145706326" variation 978 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:201505674" variation 994 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:370381369" variation 999 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="c" /db_xref="dbSNP:151032703" variation 1083 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:61756235" variation 1094 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:140951984" exon 1128..1308 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /inference="alignment:Splign:1.39.8" variation 1151 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:200583935" variation 1160 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:150198888" variation 1161 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:200840068" variation 1164 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:201456101" variation 1220 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:201943285" variation 1221 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="t" /db_xref="dbSNP:200371583" variation 1241 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="g" /replace="t" /db_xref="dbSNP:145745293" variation 1261 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:374243533" exon 1309..2228 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /inference="alignment:Splign:1.39.8" variation 1355 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:371548901" variation 1384 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:374987145" variation 1411 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:201483159" variation 1426 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:200595071" variation 1451 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:368146619" variation 1464 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:371258341" variation 1515 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:140616865" variation 1536 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:370736888" variation 1597 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:373211004" variation 1602 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:367828699" variation 1623 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:144728856" variation 1624 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:61748667" variation 1627 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:141837650" variation 1650 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:371312281" variation 1666 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="g" /db_xref="dbSNP:143619694" variation 1689 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="g" /replace="t" /db_xref="dbSNP:374721883" variation 1690 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="g" /db_xref="dbSNP:201600532" variation 1692 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:375007264" variation 1699 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:369402265" variation 1720 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="g" /db_xref="dbSNP:200878487" variation 1780 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="t" /db_xref="dbSNP:377072679" variation 1812 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:201074555" variation 1823 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:141614391" variation 1827 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:150513567" variation 1831 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:375599053" variation 1846 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:368271377" STS 1856..2121 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /standard_name="PMC355833P3" /db_xref="UniSTS:273255" variation 1871 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:140357085" variation 1888 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:202233466" variation 1956 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:142752989" variation 2016 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:370705859" variation 2025 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:374368025" variation 2026 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:147508242" variation 2050 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:140120540" variation 2058 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="g" /db_xref="dbSNP:368025276" variation 2061 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:200132284" variation 2075 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:190199205" variation 2082 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:150056192" variation 2093 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="c" /db_xref="dbSNP:145392420" variation 2131 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="g" /replace="t" /db_xref="dbSNP:201052251" variation 2152 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:199702896" variation 2212 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:148802108" variation 2228 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:200138929" exon 2229..2410 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /inference="alignment:Splign:1.39.8" variation 2261 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="c" /db_xref="dbSNP:142253225" variation 2290 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:146788699" variation 2358 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:140610274" exon 2411..4690 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /inference="alignment:Splign:1.39.8" variation 2412 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:201429571" variation 2439 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:3734553" variation 2462 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="g" /db_xref="dbSNP:369155845" variation 2476 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:145731932" variation 2489 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:146720688" variation 2497 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:140354477" variation 2504 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:373799889" variation 2535 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="t" /db_xref="dbSNP:199673474" variation 2553 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:150355046" variation 2568 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:201238112" variation 2576 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:138068339" variation 2595 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="c" /db_xref="dbSNP:377038705" variation 2604 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:368859219" variation 2610 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:369621216" variation 2617 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:5029956" variation 2618 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="g" /db_xref="dbSNP:5029957" variation 2686 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:143002189" variation 2715 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="g" /db_xref="dbSNP:373379580" variation 2775 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="g" /db_xref="dbSNP:146085256" variation 2796 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="g" /replace="t" /db_xref="dbSNP:140042278" STS 2815..2909 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /standard_name="D6S1833" /db_xref="UniSTS:51875" variation 2847 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:143551019" variation 3023 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="g" /db_xref="dbSNP:146885399" variation 3080 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:77191406" variation 3105 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="c" /db_xref="dbSNP:76710415" variation 3192 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:373372607" STS 3207..4081 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /standard_name="TNFAIP3_431" /db_xref="UniSTS:277825" variation 3337 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:73778206" variation 3528 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="t" /db_xref="dbSNP:5029966" STS 3529..3771 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /standard_name="G10608" /db_xref="UniSTS:79322" variation 3541 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:182842072" variation 3551 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:148995655" variation 3594 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:187746434" variation 3627 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="g" /replace="t" /db_xref="dbSNP:191520762" variation 3660 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="g" /db_xref="dbSNP:184063064" variation 3685 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:113524093" variation 3755 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:187253173" STS 3775..3916 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /standard_name="D6S1858" /db_xref="UniSTS:42178" STS 3775..3892 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /standard_name="D6S2077" /db_xref="UniSTS:56662" variation 3775 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="g" /replace="t" /db_xref="dbSNP:5029967" STS 3805..3923 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /standard_name="SHGC-132182" /db_xref="UniSTS:170697" variation 3885 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:370877177" variation 3902 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /replace="t" /db_xref="dbSNP:5029968" variation 3926 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="c" /db_xref="dbSNP:368124900" polyA_signal 3940..3945 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" polyA_site 3969 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" variation 3981 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:73566247" variation 4013 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:151101149" variation 4095 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="g" /db_xref="dbSNP:192024473" variation 4125 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:73778207" variation 4145 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="g" /replace="t" /db_xref="dbSNP:201356190" STS 4210..4403 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /standard_name="STS-M59465" /db_xref="UniSTS:50983" variation 4210 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="g" /replace="t" /db_xref="dbSNP:12661" variation 4240 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:145896014" variation 4255..4256 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="" /replace="a" /db_xref="dbSNP:71691390" polyA_signal 4440..4445 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" polyA_site 4464 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" STS 4504..4665 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /standard_name="STS-R70479" /db_xref="UniSTS:6382" variation 4547 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="a" /replace="g" /db_xref="dbSNP:73778208" variation 4548 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:5029958" variation 4581 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:200016426" variation 4642 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" /replace="c" /replace="t" /db_xref="dbSNP:60589019" polyA_signal 4670..4675 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" polyA_site 4690 /gene="TNFAIP3" /gene_synonym="A20; OTUD7C; TNFA1P2" ORIGIN
ctttggaaagtcccgtggaaatccccgggcctacaacccgcatacaactgaaacggggcaaagcagactgcgcagtctgcagtcttcgtggcgggccaagcgagcttggagcccgcgggggcggagcggtgagagcggccgccaagagagatcacacccccagccgaccctgccagcgagcgagcccgaccccaggcgtccatggagcgtcgcctccgcccggtccctgccccgacccccgcctgcggcgcgctcctgccttgaccaggacttgggactttgcgaaaggatcgcggggcccggagaggtgttggagagcacaatggctgaacaagtccttcctcaggctttgtatttgagcaatatgcggaaagctgtgaagatacgggagagaactccagaagacatttttaaacctactaatgggatcattcatcattttaaaaccatgcaccgatacacactggaaatgttcagaacttgccagttttgtcctcagtttcgggagatcatccacaaagccctcatcgacagaaacatccaggccaccctggaaagccagaagaaactcaactggtgtcgagaagtccggaagcttgtggcgctgaaaacgaacggtgacggcaattgcctcatgcatgccacttctcagtacatgtggggcgttcaggacacagacttggtactgaggaaggcgctgttcagcacgctcaaggaaacagacacacgcaactttaaattccgctggcaactggagtctctcaaatctcaggaatttgttgaaacggggctttgctatgatactcggaactggaatgatgaatgggacaatcttatcaaaatggcttccacagacacacccatggcccgaagtggacttcagtacaactcactggaagaaatacacatatttgtcctttgcaacatcctcagaaggccaatcattgtcatttcagacaaaatgctaagaagtttggaatcaggttccaatttcgcccctttgaaagtgggtggaatttacttgcctctccactggcctgcccaggaatgctacagataccccattgttctcggctatgacagccatcattttgtacccttggtgaccctgaaggacagtgggcctgaaatccgagctgttccacttgttaacagagaccggggaagatttgaagacttaaaagttcactttttgacagatcctgaaaatgagatgaaggagaagctcttaaaagagtacttaatggtgatagaaatccccgtccaaggctgggaccatggcacaactcatctcatcaatgccgcaaagttggatgaagctaacttaccaaaagaaatcaatctggtagatgattactttgaacttgttcagcatgagtacaagaaatggcaggaaaacagcgagcaggggaggagagaggggcacgcccagaatcccatggaaccttccgtgccccagctttctctcatggatgtaaaatgtgaaacgcccaactgccccttcttcatgtctgtgaacacccagcctttatgccatgagtgctcagagaggcggcaaaagaatcaaaacaaactcccaaagctgaactccaagccgggccctgaggggctccctggcatggcgctcggggcctctcggggagaagcctatgagcccttggcgtggaaccctgaggagtccactggggggcctcattcggccccaccgacagcacccagcccttttctgttcagtgagaccactgccatgaagtgcaggagccccggctgccccttcacactgaatgtgcagcacaacggattttgtgaacgttgccacaacgcccggcaacttcacgccagccacgccccagaccacacaaggcacttggatcccgggaagtgccaagcctgcctccaggatgttaccaggacatttaatgggatctgcagtacttgcttcaaaaggactacagcagaggcctcctccagcctcagcaccagcctccctccttcctgtcaccagcgttccaagtcagatccctcgcggctcgtccggagcccctccccgcattcttgccacagagctggaaacgacgcccctgctggctgcctgtctcaagctgcacggactcctggggacaggacggggacgagcaagtgcagaaaagccggctgcgtgtattttgggactccagaaaacaagggcttttgcacactgtgtttcatcgagtacagagaaaacaaacattttgctgctgcctcagggaaagtcagtcccacagcgtccaggttccagaacaccattccgtgcctggggagggaatgcggcacccttggaagcaccatgtttgaaggatactgccagaagtgtttcattgaagctcagaatcagagatttcatgaggccaaaaggacagaagagcaactgagatcgagccagcgcagagatgtgcctcgaaccacacaaagcacctcaaggcccaagtgcgcccgggcctcctgcaagaacatcctggcctgccgcagcgaggagctctgcatggagtgtcagcatcccaaccagaggatgggccctggggcccaccggggtgagcctgcccccgaagacccccccaagcagcgttgccgggcccccgcctgtgatcattttggcaatgccaagtgcaacggctactgcaacgaatgctttcagttcaagcagatgtatggctaaccggaaacaggtgggtcacctcctgcaagaagtggggcctcgagctgtcagtcatcatggtgctatcctctgaacccctcagctgccactgcaacagtgggcttaagggtgtctgagcaggagaggaaagataagctcttcgtggtgcccacgatgctcaggtttggtaacccgggagtgttcccaggtggccttagaaagcaaagcttgtaactggcaagggatgatgtcagattcagcccaaggttcctcctctcctaccaagcaggaggccaggaacttctttggacttggaaggtgtgcggggactggccgaggcccctgcaccctgcgcatcaggactgcttcatcgtcttggctgagaaagggaaaagacacacaagtcgcgtgggttggagaagccagagccattccacctcccctcccccagcatctctcagagatgtgaagccagatcctcatggcagcgaggccctctgcaagaagctcaaggaagctcagggaaaatggacgtattcagagagtgtttgtagttcatggtttttccctacctgcccggttcctttcctgaggacccggcagaaatgcagaaccatccatggactgtgattctgaggctgctgagactgaacatgttcacattgacagaaaaacaagctgctctttataatatgcaccttttaaaaaattagaatattttactgggaagacgtgtaactctttgggttattactgtctttacttctaaagaagttagcttgaactgaggagtaaaagtgtgtacatatataatatacccttacattatgtatgagggatttttttaaattatattgaaatgctgccctagaagtacaataggaaggctaaataataataacctgttttctggttgttgttggggcatgagcttgtgtatacactgcttgcataaactcaaccagctgcctttttaaagggagctctagtcctttttgtgtaattcactttatttattttattacaaacttcaagattatttaagtgaagatatttcttcagctctggggaaaatgccacagtgttctcctgagagaacatccttgctttgagtcaggctgtgggcaagttcctgaccacagggagtaaattggcctctttgatacacttttgcttgcctccccaggaaagaaggaattgcatccaaggtatacatacatattcatcgatgtttcgtgcttctccttatgaaactccagctatgtaataaaaaactatactctgtgttctgttaatgcctctgagtgtcctacctccttggagatgagatagggaaggagcagggatgagactggcaatggtcacagggaaagatgtggccttttgtgatggttttattttctgttaacactgtgtcctgggggggctgggaagtcccctgcatcccatggtaccctggtattgggacagcaaaagccagtaaccatgagtatgaggaaatctctttctgttgctggcttacagtttctctgtgtgctttgtggttgctgtcatatttgctctagaagaaaaaaaaaaaaggaggggaaatgcattttccccagagataaaggctgccattttgggggtctgtacttatggcctgaaaatatttgtgatccataactctacacagcctttactcatactattaggcacactttccccttagagccccctaagtttttcccagacgaatctttataatttctttccaaagataccaaataaacttcagtgttttcatctaattctcttaaagttgatatcttaatattttgtgttgatcattatttccattcttaatgtgaaaaaaagtaattatttatacttattataaaaagtatttgaaatttgcacatttaattgtccctaatagaaagccacctattctttgttggatttcttcaagtttttctaaataaatgtaacttttcacaagagtcaacattaaaaaataaattatttaagaacagaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726): GeneID:7128 -> Molecular function: GO:0002020 [protease binding] evidence: IPI GeneID:7128 -> Molecular function: GO:0003677 [DNA binding] evidence: IEA GeneID:7128 -> Molecular function: GO:0004221 [ubiquitin thiolesterase activity] evidence: IMP GeneID:7128 -> Molecular function: GO:0004842 [ubiquitin-protein ligase activity] evidence: IDA GeneID:7128 -> Molecular function: GO:0004843 [ubiquitin-specific protease activity] evidence: IDA GeneID:7128 -> Molecular function: GO:0004843 [ubiquitin-specific protease activity] evidence: TAS GeneID:7128 -> Molecular function: GO:0005515 [protein binding] evidence: IPI GeneID:7128 -> Molecular function: GO:0008270 [zinc ion binding] evidence: IEA GeneID:7128 -> Molecular function: GO:0019900 [kinase binding] evidence: IEA GeneID:7128 -> Molecular function: GO:0043130 [ubiquitin binding] evidence: IPI GeneID:7128 -> Molecular function: GO:0043621 [protein self-association] evidence: IDA GeneID:7128 -> Biological process: GO:0001922 [B-1 B cell homeostasis] evidence: ISS GeneID:7128 -> Biological process: GO:0002237 [response to molecule of bacterial origin] evidence: IDA GeneID:7128 -> Biological process: GO:0002634 [regulation of germinal center formation] evidence: ISS GeneID:7128 -> Biological process: GO:0002677 [negative regulation of chronic inflammatory response] evidence: IEA GeneID:7128 -> Biological process: GO:0006508 [proteolysis] evidence: IEA GeneID:7128 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA GeneID:7128 -> Biological process: GO:0006954 [inflammatory response] evidence: IEA GeneID:7128 -> Biological process: GO:0016579 [protein deubiquitination] evidence: TAS GeneID:7128 -> Biological process: GO:0031397 [negative regulation of protein ubiquitination] evidence: IDA GeneID:7128 -> Biological process: GO:0032088 [negative regulation of NF-kappaB transcription factor activity] evidence: IDA GeneID:7128 -> Biological process: GO:0032480 [negative regulation of type I interferon production] evidence: TAS GeneID:7128 -> Biological process: GO:0032495 [response to muramyl dipeptide] evidence: IEA GeneID:7128 -> Biological process: GO:0032691 [negative regulation of interleukin-1 beta production] evidence: IEA GeneID:7128 -> Biological process: GO:0032703 [negative regulation of interleukin-2 production] evidence: IMP GeneID:7128 -> Biological process: GO:0032715 [negative regulation of interleukin-6 production] evidence: ISS GeneID:7128 -> Biological process: GO:0032720 [negative regulation of tumor necrosis factor production] evidence: ISS GeneID:7128 -> Biological process: GO:0034136 [negative regulation of toll-like receptor 2 signaling pathway] evidence: NAS GeneID:7128 -> Biological process: GO:0034140 [negative regulation of toll-like receptor 3 signaling pathway] evidence: IDA GeneID:7128 -> Biological process: GO:0034144 [negative regulation of toll-like receptor 4 signaling pathway] evidence: NAS GeneID:7128 -> Biological process: GO:0034148 [negative regulation of toll-like receptor 5 signaling pathway] evidence: IEA GeneID:7128 -> Biological process: GO:0035872 [nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway] evidence: TAS GeneID:7128 -> Biological process: GO:0043066 [negative regulation of apoptotic process] evidence: NAS GeneID:7128 -> Biological process: GO:0043124 [negative regulation of I-kappaB kinase/NF-kappaB cascade] evidence: IDA GeneID:7128 -> Biological process: GO:0045087 [innate immune response] evidence: TAS GeneID:7128 -> Biological process: GO:0045732 [positive regulation of protein catabolic process] evidence: IDA GeneID:7128 -> Biological process: GO:0045736 [negative regulation of cyclin-dependent protein serine/threonine kinase activity] evidence: IEA GeneID:7128 -> Biological process: GO:0045779 [negative regulation of bone resorption] evidence: NAS GeneID:7128 -> Biological process: GO:0045824 [negative regulation of innate immune response] evidence: ISS GeneID:7128 -> Biological process: GO:0048662 [negative regulation of smooth muscle cell proliferation] evidence: IDA GeneID:7128 -> Biological process: GO:0050691 [regulation of defense response to virus by host] evidence: NAS GeneID:7128 -> Biological process: GO:0050728 [negative regulation of inflammatory response] evidence: ISS GeneID:7128 -> Biological process: GO:0050869 [negative regulation of B cell activation] evidence: ISS GeneID:7128 -> Biological process: GO:0051259 [protein oligomerization] evidence: NAS GeneID:7128 -> Biological process: GO:0061043 [regulation of vascular wound healing] evidence: NAS GeneID:7128 -> Biological process: GO:0070301 [cellular response to hydrogen peroxide] evidence: ISS GeneID:7128 -> Biological process: GO:0070423 [nucleotide-binding oligomerization domain containing signaling pathway] evidence: TAS GeneID:7128 -> Biological process: GO:0070429 [negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway] evidence: IEA GeneID:7128 -> Biological process: GO:0070433 [negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway] evidence: IEA GeneID:7128 -> Biological process: GO:0070536 [protein K63-linked deubiquitination] evidence: IDA GeneID:7128 -> Biological process: GO:0070936 [protein K48-linked ubiquitination] evidence: IDA GeneID:7128 -> Biological process: GO:0071222 [cellular response to lipopolysaccharide] evidence: IDA GeneID:7128 -> Biological process: GO:0072573 [tolerance induction to lipopolysaccharide] evidence: IMP GeneID:7128 -> Biological process: GO:0090291 [negative regulation of osteoclast proliferation] evidence: NAS GeneID:7128 -> Biological process: GO:1902042 [negative regulation of extrinsic apoptotic signaling pathway via death domain receptors] evidence: IDA GeneID:7128 -> Biological process: GO:2000347 [positive regulation of hepatocyte proliferation] evidence: IEA GeneID:7128 -> Biological process: GO:2000349 [negative regulation of CD40 signaling pathway] evidence: IMP GeneID:7128 -> Biological process: GO:2000352 [negative regulation of endothelial cell apoptotic process] evidence: IDA GeneID:7128 -> Cellular component: GO:0005634 [nucleus] evidence: IDA GeneID:7128 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA GeneID:7128 -> Cellular component: GO:0005764 [lysosome] evidence: IEA GeneID:7128 -> Cellular component: GO:0005813 [centrosome] evidence: IDA GeneID:7128 -> Cellular component: GO:0005829 [cytosol] evidence: TAS ANNOTATIONS from NCBI Entrez Gene (20130726): NP_006281 -> EC 3.4.19.12
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