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2024-04-19 10:08:35, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_006265 3773 bp mRNA linear PRI 07-JUL-2013
DEFINITION Homo sapiens RAD21 homolog (S. pombe) (RAD21), mRNA.
ACCESSION NM_006265
VERSION NM_006265.2 GI:208879448
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3773)
AUTHORS Wu,N., Kong,X., Ji,Z., Zeng,W., Potts,P.R., Yokomori,K. and Yu,H.
TITLE Scc1 sumoylation by Mms21 promotes sister chromatid recombination
through counteracting Wapl
JOURNAL Genes Dev. 26 (13), 1473-1485 (2012)
PUBMED 22751501
REMARK GeneRIF: show that the Smc5/6 subunit Mms21 sumoylates multiple
lysines of the cohesin subunit Scc1
REFERENCE 2 (bases 1 to 3773)
AUTHORS Deardorff,M.A., Wilde,J.J., Albrecht,M., Dickinson,E.,
Tennstedt,S., Braunholz,D., Monnich,M., Yan,Y., Xu,W.,
Gil-Rodriguez,M.C., Clark,D., Hakonarson,H., Halbach,S.,
Michelis,L.D., Rampuria,A., Rossier,E., Spranger,S., Van
Maldergem,L., Lynch,S.A., Gillessen-Kaesbach,G., Ludecke,H.J.,
Ramsay,R.G., McKay,M.J., Krantz,I.D., Xu,H., Horsfield,J.A. and
Kaiser,F.J.
TITLE RAD21 mutations cause a human cohesinopathy
JOURNAL Am. J. Hum. Genet. 90 (6), 1014-1027 (2012)
PUBMED 22633399
REMARK GeneRIF: RAD21 mutations cause a human cohesinopathy
REFERENCE 3 (bases 1 to 3773)
AUTHORS Yan M, Xu H, Waddell N, Shield-Artin K, Haviv I, McKay MJ and Fox
SB.
CONSRTM kConFab authors
TITLE Enhanced RAD21 cohesin expression confers poor prognosis in BRCA2
and BRCAX, but not BRCA1 familial breast cancers
JOURNAL Breast Cancer Res. 14 (2), R69 (2012)
PUBMED 22537934
REMARK GeneRIF: RAD21 expression is associated with a poorer prognosis in
BRCA2, but not in BRCA1 breast cancers.
Publication Status: Online-Only
REFERENCE 4 (bases 1 to 3773)
AUTHORS Panigrahi,A.K., Zhang,N., Mao,Q. and Pati,D.
TITLE Calpain-1 cleaves Rad21 to promote sister chromatid separation
JOURNAL Mol. Cell. Biol. 31 (21), 4335-4347 (2011)
PUBMED 21876002
REMARK GeneRIF: Rad21 cleavage by calpain-1 promotes separation of
chromosome arms, which coincides with a calcium-induced partial
loss of cohesin at several chromosomal loci.
REFERENCE 5 (bases 1 to 3773)
AUTHORS Gimenez-Abian,J.F., Diaz-Martinez,L.A., Beauchene,N.A., Hsu,W.S.,
Tsai,H.J. and Clarke,D.J.
TITLE Determinants of Rad21 localization at the centrosome in human cells
JOURNAL Cell Cycle 9 (9), 1759-1763 (2010)
PUBMED 20404544
REMARK GeneRIF: Rad21 protein are cleaved by separase are required for the
localization of Rad21 to the centrosome.
REFERENCE 6 (bases 1 to 3773)
AUTHORS Hoque,M.T. and Ishikawa,F.
TITLE Human chromatid cohesin component hRad21 is phosphorylated in M
phase and associated with metaphase centromeres
JOURNAL J. Biol. Chem. 276 (7), 5059-5067 (2001)
PUBMED 11073952
REFERENCE 7 (bases 1 to 3773)
AUTHORS Losada,A., Yokochi,T., Kobayashi,R. and Hirano,T.
TITLE Identification and characterization of SA/Scc3p subunits in the
Xenopus and human cohesin complexes
JOURNAL J. Cell Biol. 150 (3), 405-416 (2000)
PUBMED 10931856
REFERENCE 8 (bases 1 to 3773)
AUTHORS Sadano,H., Sugimoto,H., Sakai,F., Nomura,N. and Osumi,T.
TITLE NXP-1, a human protein related to Rad21/Scc1/Mcd1, is a component
of the nuclear matrix
JOURNAL Biochem. Biophys. Res. Commun. 267 (1), 418-422 (2000)
PUBMED 10623634
REFERENCE 9 (bases 1 to 3773)
AUTHORS Parisi,S., McKay,M.J., Molnar,M., Thompson,M.A., van der Spek,P.J.,
van Drunen-Schoenmaker,E., Kanaar,R., Lehmann,E., Hoeijmakers,J.H.
and Kohli,J.
TITLE Rec8p, a meiotic recombination and sister chromatid cohesion
phosphoprotein of the Rad21p family conserved from fission yeast to
humans
JOURNAL Mol. Cell. Biol. 19 (5), 3515-3528 (1999)
PUBMED 10207075
REFERENCE 10 (bases 1 to 3773)
AUTHORS McKay,M.J., Troelstra,C., van der Spek,P., Kanaar,R., Smit,B.,
Hagemeijer,A., Bootsma,D. and Hoeijmakers,J.H.
TITLE Sequence conservation of the rad21 Schizosaccharomyces pombe DNA
double-strand break repair gene in human and mouse
JOURNAL Genomics 36 (2), 305-315 (1996)
PUBMED 8812457
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DA328186.1 and BC050381.1.
This sequence is a reference standard in the RefSeqGene project.
On Oct 7, 2008 this sequence version replaced gi:5453993.
Summary: The protein encoded by this gene is highly similar to the
gene product of Schizosaccharomyces pombe rad21, a gene involved in
the repair of DNA double-strand breaks, as well as in chromatid
cohesion during mitosis. This protein is a nuclear phospho-protein,
which becomes hyperphosphorylated in cell cycle M phase. The highly
regulated association of this protein with mitotic chromatin
specifically at the centromere region suggests its role in sister
chromatid cohesion in mitotic cells. [provided by RefSeq, Jul
2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC050381.1, D38551.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
ERS025081, ERS025082 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-160 DA328186.1 1-160
161-3773 BC050381.1 1-3613
FEATURES Location/Qualifiers
source 1..3773
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="8"
/map="8q24"
gene 1..3773
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/note="RAD21 homolog (S. pombe)"
/db_xref="GeneID:5885"
/db_xref="HGNC:9811"
/db_xref="HPRD:05924"
/db_xref="MIM:606462"
exon 1..256
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/inference="alignment:Splign:1.39.8"
variation 238
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/replace="a"
/replace="t"
/db_xref="dbSNP:16889189"
exon 257..432
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/inference="alignment:Splign:1.39.8"
misc_feature 274..276
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/note="upstream in-frame stop codon"
CDS 289..2184
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/note="protein involved in DNA double-strand break repair;
nuclear matrix protein 1; NXP-1; SCC1 homolog"
/codon_start=1
/product="double-strand-break repair protein rad21
homolog"
/protein_id="NP_006256.1"
/db_xref="GI:5453994"
/db_xref="CCDS:CCDS6321.1"
/db_xref="GeneID:5885"
/db_xref="HGNC:9811"
/db_xref="HPRD:05924"
/db_xref="MIM:606462"
/translation="
MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIISPKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAYNAITLPEEFHDFDQPLPDLDDIDVAQQFSLNQSRVEEITMREEVGNISILQENDFGDFGMDDREIMREGSAFEDDDMLVSTTTSNLLLESEQSTSNLNEKINHLEYEDQYKDDNFGEGNDGGILDDKLISNNDGGIFDDPPALSEAGVMLPEQPAHDDMDEDDNVSMGGPDSPDSVDPVEPMPTMTDQTTLVPNEEEAFALEPIDITVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKLMMWKETGGVEKLFSLPAQPLWNNRLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEEPYSDIIATPGPRFHII
"
misc_feature 289..621
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/note="N terminus of Rad21 / Rec8 like protein; Region:
Rad21_Rec8_N; pfam04825"
/db_xref="CDD:203097"
misc_feature 424..426
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(O60216.2); phosphorylation site"
misc_feature 745..747
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(O60216.2); phosphorylation site"
misc_feature 802..807
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/experiment="experimental evidence, no additional details
recorded"
/note="Cleavage, by ESPL1; propagated from
UniProtKB/Swiss-Prot (O60216.2); cleavage site"
misc_feature 811..813
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(O60216.2); phosphorylation site"
misc_feature 1123..1128
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/experiment="experimental evidence, no additional details
recorded"
/note="Cleavage, by caspase-3 or caspase-7; propagated
from UniProtKB/Swiss-Prot (O60216.2); cleavage site"
misc_feature 1123..1125
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/experiment="experimental evidence, no additional details
recorded"
/note="proteolytic cleavage site; modified site"
/db_xref="HPRD:02799"
misc_feature 1123..1125
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/experiment="experimental evidence, no additional details
recorded"
/note="proteolytic cleavage site; modified site"
/db_xref="HPRD:03457"
misc_feature 1147..1497
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (O60216.2);
Region: Interaction with WAPAL and PDS5B"
misc_feature 1372..1497
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (O60216.2);
Region: Interaction with STAG1"
misc_feature 1636..1641
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/experiment="experimental evidence, no additional details
recorded"
/note="Cleavage, by ESPL1; propagated from
UniProtKB/Swiss-Prot (O60216.2); cleavage site"
misc_feature 2008..2172
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/note="Conserved region of Rad21 / Rec8 like protein;
Region: Rad21_Rec8; pfam04824"
/db_xref="CDD:113590"
exon 433..562
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/inference="alignment:Splign:1.39.8"
exon 563..662
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/inference="alignment:Splign:1.39.8"
exon 663..769
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/inference="alignment:Splign:1.39.8"
exon 770..976
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/inference="alignment:Splign:1.39.8"
exon 977..1102
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/inference="alignment:Splign:1.39.8"
exon 1103..1225
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/inference="alignment:Splign:1.39.8"
exon 1226..1449
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/inference="alignment:Splign:1.39.8"
exon 1450..1609
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/inference="alignment:Splign:1.39.8"
STS 1570..1806
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/standard_name="STS-Z78334"
/db_xref="UniSTS:73861"
exon 1610..1758
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/inference="alignment:Splign:1.39.8"
STS 1614..1744
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/standard_name="G29205"
/db_xref="UniSTS:38977"
STS 1699..1859
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/standard_name="SHGC-37645"
/db_xref="UniSTS:29783"
variation 1728
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:1050838"
exon 1759..1908
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/inference="alignment:Splign:1.39.8"
exon 1909..1992
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/inference="alignment:Splign:1.39.8"
exon 1993..3750
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/inference="alignment:Splign:1.39.8"
STS 2250..2420
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/standard_name="RH25306"
/db_xref="UniSTS:89346"
STS 2435..2547
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/standard_name="D3S3884"
/db_xref="UniSTS:27233"
variation 2483
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:11548734"
STS 2728..2858
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/standard_name="Bda37g02"
/db_xref="UniSTS:27426"
variation 2864
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:15527"
variation 2979..2980
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/replace=""
/replace="tgtt"
/db_xref="dbSNP:16918290"
STS 3150..3301
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/standard_name="RH65259"
/db_xref="UniSTS:92992"
STS 3150..3250
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/standard_name="G42913"
/db_xref="UniSTS:94819"
variation 3180
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/replace="a"
/replace="c"
/db_xref="dbSNP:2434"
variation 3316..3317
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/replace=""
/replace="at"
/db_xref="dbSNP:16918570"
variation 3351
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/replace="c"
/replace="g"
/db_xref="dbSNP:1804044"
variation 3390
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/replace=""
/replace="a"
/db_xref="dbSNP:16918579"
STS 3441..3579
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/standard_name="G54034"
/db_xref="UniSTS:109416"
variation 3534
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:4570"
variation 3573
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/replace="c"
/replace="t"
/db_xref="dbSNP:14795"
STS 3600..3706
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
/standard_name="WI-14191"
/db_xref="UniSTS:62229"
polyA_signal 3726..3731
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
polyA_site 3750
/gene="RAD21"
/gene_synonym="CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1;
SCC1"
ORIGIN
aggcgcacaggtaccattttgaccgtaaacatcctgccgatttgaaccgaggatttgggcggcaggaagagccgcggcgtaacggcagccatcttgtttgtttgagtgaatcggaaaggaggcgccggctgtggcggcggcgggagctgctcggaagctacacctcgcaagggctcccccctttccccaccccctcccccgacccttttcccctccccgggccacccagcccgcccaactcccagcggagagcaaggttttcttctgttttcatagccagccagaacaatgttctacgcacattttgttctcagtaaaagagggcctctggccaaaatttggctagcggcccattgggataagaagctaaccaaagcccatgtgttcgagtgtaatttagagagcagcgtggagagtatcatctcaccaaaggtgaaaatggcattacggacatcaggacatctcttactgggagtagttcgaatctatcacaggaaagccaaataccttcttgcagactgtaatgaagcattcattaagataaagatggcttttcggccaggtgtggttgacctgcctgaggaaaatcgggaagcagcttataatgccattactttacctgaagaatttcatgactttgatcagccactgcctgacttagatgacatcgatgtggcccagcagttcagcttgaatcagagtagagtggaagagataaccatgagagaagaagttgggaacatcagtattttacaagaaaatgattttggtgattttggaatggatgatcgtgagataatgagagaaggcagtgcttttgaggatgacgacatgttagtaagcactactacttctaacctcctattagagtctgaacagagcaccagcaatctgaatgagaaaattaaccatttagaatatgaagatcaatataaggatgataattttggagaaggaaatgatggtggaatattagatgacaaacttattagtaataatgatggcggtatctttgatgatccccctgccctctctgaggcaggggtgatgttgccagagcagcctgcacatgacgatatggatgaggatgataatgtatcaatgggtgggcctgatagtcctgattcagtggatcccgttgaaccaatgccaaccatgactgatcaaacaacacttgttccaaatgaggaagaagcatttgcattggagcctattgatataactgttaaagaaacaaaagccaagaggaagaggaagctaattgttgacagtgtcaaagagttggatagcaagacaattagagcccaacttagtgattattcagatattgttactactttggatctggcaccgcccaccaagaaattgatgatgtggaaagagacaggaggagtagaaaaactgttttctttacctgctcagcctttgtggaataacagactactgaagctctttacacgctgtcttacaccgcttgtaccagaagaccttagaaaaaggaggaaaggaggagaggcagataatttggatgaattcctcaaagaatttgaaaatccagaggttcctagagaggaccagcaacagcagcatcagcagcgtgatgttatcgatgagcccattattgaagagccaagccgcctccaggagtcagtgatggaggccagcagaacaaacatagatgagtcagctatgcctccaccaccacctcagggagttaagcgaaaagctggacaaattgacccagagcctgtgatgcctcctcagcaggtagagcagatggaaataccacctgtagagcttcccccagaagaacctccaaatatctgtcagctaataccagagttagaacttctgccagaaaaagagaaggagaaagagaaggaaaaagaagatgatgaagaggaagaggatgaagatgcatcagggggcgatcaagatcaggaagaaagaagatggaacaaaaggactcagcagatgcttcatggtcttcagcgtgctcttgctaaaactggagctgaatctatcagtttgcttgagttatgtcgaaatacgaacagaaaacaagctgccgcaaagttctacagcttcttggttcttaaaaagcagcaagctattgagctgacacaggaagaaccgtacagtgacatcatcgcaacacctggaccaaggttccatattatataaggagctagaagcattatagctagtgtttgattcactagtgcttacaaattgcccccatgtgtaggggacacagaaccctttgagaaaacttagatttttgtctgtacaaagtctttgcctttttccttcttcatttttttccagtacattaaatttgtcaatttcatctttgagggaaactgattagatgggttgtgtttgtgttctgatggagaaaacagcaccccaaggactcagaagatgattttaacagttcagaacagatgtgtgcaatattggtgcatgtaataatgttgagtggcagtcaaaagtcatgatttttatcttagttcttcattactgcattgaaaaggaaaacctgtctgagaaaatgcctgacagtttaatttaaaactatggtgtaagtctttgacaagaaaaaaaaacaaacaaacacttctttccatcagtaacactggcaatcttcctgttaaccactctccttagggatggtatctgaaacaacaatggtcaccctcttgagattcgttttaagtgtaattccataatgagcagaggtgtacgcgaaattgtgttatgactgatagccttcagctacaaaaagataggactgacctggtttaaagtgttctattttgtaaatcattccatttgagtctttctgatgaacttggctatactgaaatctgttattttagtgaggctccaaaatgagcaaagctaggcctgattagagtagagtgactattaaaaaacataactttctaggagctataaatcaaagttttaaaaagatgtttggatatatttgagtattccgatcatgaaaacagaaattgccctgcctactacaaggacagactgatgggaaattatgcacctggtcaacttagcttttaagcagacgatgctgtaaaaactaacggcttctctgatatttattgtaagttttagtactgatctccttttccagtgctgcacactcctggtttggaactttaatagcgttgcaacgaaatcctatatccagtttcctgtaatttaattgaagaaaaatacatccaaataaagactttattattaacagaccagatagcatcagaaatcatgtgactgttatgattatcagaatgtcttaactttttagggcaaagttaacactgaaagttctagcttaagtgttgaaacttttgtgggaaaaaaaaatcacttttgaaactcagacttcagtgtatacccaataatttaaaattatgtgaaatgttttaaatttgtgaactcgtaattactgttttaatgattcagtttcttcagagtggtaattgtataaaattgctattgcagctttacattcaatatgatgtgcctgtaaaccaaggagttttccccgtttgtaaaaagacattgtagataattgaatgtttgattttagaaaggtcattagtttcttgttacacattttgttagtctggtttttgttgcttatcgggtttaatattgttcttgaaaatagttgatgctatgttatgtataacttttctaataaaagttgtgttataagctgtaaaaaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:5885 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:5885 -> Biological process: GO:0000278 [mitotic cell cycle] evidence: TAS
GeneID:5885 -> Biological process: GO:0000910 [cytokinesis] evidence: TAS
GeneID:5885 -> Biological process: GO:0006302 [double-strand break repair] evidence: TAS
GeneID:5885 -> Biological process: GO:0006310 [DNA recombination] evidence: TAS
GeneID:5885 -> Biological process: GO:0006357 [regulation of transcription from RNA polymerase II promoter] evidence: IDA
GeneID:5885 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:5885 -> Biological process: GO:0007059 [chromosome segregation] evidence: IEA
GeneID:5885 -> Biological process: GO:0007067 [mitosis] evidence: IEA
GeneID:5885 -> Biological process: GO:0007131 [reciprocal meiotic recombination] evidence: TAS
GeneID:5885 -> Biological process: GO:0071168 [protein localization to chromatin] evidence: IMP
GeneID:5885 -> Cellular component: GO:0000775 [chromosome, centromeric region] evidence: TAS
GeneID:5885 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:5885 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
GeneID:5885 -> Cellular component: GO:0005694 [chromosome] evidence: TAS
GeneID:5885 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
GeneID:5885 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:5885 -> Cellular component: GO:0008278 [cohesin complex] evidence: TAS
GeneID:5885 -> Cellular component: GO:0034991 [nuclear meiotic cohesin complex] evidence: IEA
by
@meso_cacase at
DBCLS
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