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2020-10-26 18:15:57, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_005087               8567 bp    mRNA    linear   PRI 07-JUL-2013
DEFINITION  Homo sapiens fragile X mental retardation, autosomal homolog 1
            (FXR1), transcript variant 1, mRNA.
ACCESSION   NM_005087
VERSION     NM_005087.3  GI:298231191
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 8567)
  AUTHORS   Davidovic,L., Durand,N., Khalfallah,O., Tabet,R., Barbry,P.,
            Mari,B., Sacconi,S., Moine,H. and Bardoni,B.
  TITLE     A novel role for the RNA-binding protein FXR1P in myoblasts
            cell-cycle progression by modulating p21/Cdkn1a/Cip1/Waf1 mRNA
            stability
  JOURNAL   PLoS Genet. 9 (3), E1003367 (2013)
   PUBMED   23555284
  REMARK    GeneRIF: Our study describes a novel role of FXR1P that has crucial
            implications for the understanding of its role during myogenesis
            and muscle development
REFERENCE   2  (bases 1 to 8567)
  AUTHORS   Coffee,R.L. Jr., Tessier,C.R., Woodruff,E.A. III and Broadie,K.
  TITLE     Fragile X mental retardation protein has a unique, evolutionarily
            conserved neuronal function not shared with FXR1P or FXR2P
  JOURNAL   Dis Model Mech 3 (7-8), 471-485 (2010)
   PUBMED   20442204
  REMARK    GeneRIF: These results indicate that FMR1 gene function is
            evolutionarily conserved in neural mechanisms and cannot be
            compensated by either FXR1 or FXR2, but that all three proteins can
            substitute for each other in non-neuronal requirements.
REFERENCE   3  (bases 1 to 8567)
  AUTHORS   Adams-Cioaba,M.A., Guo,Y., Bian,C., Amaya,M.F., Lam,R.,
            Wasney,G.A., Vedadi,M., Xu,C. and Min,J.
  TITLE     Structural studies of the tandem Tudor domains of fragile X mental
            retardation related proteins FXR1 and FXR2
  JOURNAL   PLoS ONE 5 (11), E13559 (2010)
   PUBMED   21072162
  REMARK    GeneRIF: Data show that the nuclear localization signals of the
            FXR1 and FXR2 comprise tandem Tudor domain architectures.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8567)
  AUTHORS   Darnell,J.C., Fraser,C.E., Mostovetsky,O. and Darnell,R.B.
  TITLE     Discrimination of common and unique RNA-binding activities among
            Fragile X mental retardation protein paralogs
  JOURNAL   Hum. Mol. Genet. 18 (17), 3164-3177 (2009)
   PUBMED   19487368
  REMARK    GeneRIF: FXR1P and FXR2P KH2 domains bind G-quadruplex and kissing
            complex RNA with the same affinity as the FMRP KH2 domain.
REFERENCE   5  (bases 1 to 8567)
  AUTHORS   Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, Sullivan
            PF and Sklar P.
  CONSRTM   International Schizophrenia Consortium
  TITLE     Common polygenic variation contributes to risk of schizophrenia and
            bipolar disorder
  JOURNAL   Nature 460 (7256), 748-752 (2009)
   PUBMED   19571811
REFERENCE   6  (bases 1 to 8567)
  AUTHORS   Tamanini,F., Willemsen,R., van Unen,L., Bontekoe,C., Galjaard,H.,
            Oostra,B.A. and Hoogeveen,A.T.
  TITLE     Differential expression of FMR1, FXR1 and FXR2 proteins in human
            brain and testis
  JOURNAL   Hum. Mol. Genet. 6 (8), 1315-1322 (1997)
   PUBMED   9259278
REFERENCE   7  (bases 1 to 8567)
  AUTHORS   Siomi,M.C., Zhang,Y., Siomi,H. and Dreyfuss,G.
  TITLE     Specific sequences in the fragile X syndrome protein FMR1 and the
            FXR proteins mediate their binding to 60S ribosomal subunits and
            the interactions among them
  JOURNAL   Mol. Cell. Biol. 16 (7), 3825-3832 (1996)
   PUBMED   8668200
REFERENCE   8  (bases 1 to 8567)
  AUTHORS   Coy,J.F., Sedlacek,Z., Bachner,D., Hameister,H., Joos,S.,
            Lichter,P., Delius,H. and Poustka,A.
  TITLE     Highly conserved 3' UTR and expression pattern of FXR1 points to a
            divergent gene regulation of FXR1 and FMR1
  JOURNAL   Hum. Mol. Genet. 4 (12), 2209-2218 (1995)
   PUBMED   8634689
REFERENCE   9  (bases 1 to 8567)
  AUTHORS   Zhang,Y., O'Connor,J.P., Siomi,M.C., Srinivasan,S., Dutra,A.,
            Nussbaum,R.L. and Dreyfuss,G.
  TITLE     The fragile X mental retardation syndrome protein interacts with
            novel homologs FXR1 and FXR2
  JOURNAL   EMBO J. 14 (21), 5358-5366 (1995)
   PUBMED   7489725
REFERENCE   10 (bases 1 to 8567)
  AUTHORS   Siomi,M.C., Siomi,H., Sauer,W.H., Srinivasan,S., Nussbaum,R.L. and
            Dreyfuss,G.
  TITLE     FXR1, an autosomal homolog of the fragile X mental retardation gene
  JOURNAL   EMBO J. 14 (11), 2401-2408 (1995)
   PUBMED   7781595
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DC352767.1, AK292633.1 and
            AC008009.5.
            On Jun 13, 2010 this sequence version replaced gi:61835147.
            
            Summary: The protein encoded by this gene is an RNA binding protein
            that interacts with the functionally-similar proteins FMR1 and
            FXR2. These proteins shuttle between the nucleus and cytoplasm and
            associate with polyribosomes, predominantly with the 60S ribosomal
            subunit. Three transcript variants encoding different isoforms have
            been found for this gene. [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U25165.1, AK292633.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025082 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-319               DC352767.1         1-319
            320-2218            AK292633.1         96-1994
            2219-8567           AC008009.5         72297-78645
FEATURES             Location/Qualifiers
     source          1..8567
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q28"
     gene            1..8567
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /note="fragile X mental retardation, autosomal homolog 1"
                     /db_xref="GeneID:8087"
                     /db_xref="HGNC:4023"
                     /db_xref="MIM:600819"
     exon            1..291
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /inference="alignment:Splign:1.39.8"
     variation       17
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:13072332"
     variation       111
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:189076195"
     variation       194
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:376999929"
     variation       214
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371117434"
     variation       232
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375850195"
     CDS             241..2106
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /note="isoform a is encoded by transcript variant 1;
                     fragile X mental retardation syndrome-related protein 1;
                     hFXR1p"
                     /codon_start=1
                     /product="fragile X mental retardation syndrome-related
                     protein 1 isoform a"
                     /protein_id="NP_005078.2"
                     /db_xref="GI:61835148"
                     /db_xref="CCDS:CCDS3238.1"
                     /db_xref="GeneID:8087"
                     /db_xref="HGNC:4023"
                     /db_xref="MIM:600819"
                     /translation="
MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEISEGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAAVLNGVS
"
     misc_feature    244..246
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N-acetylalanine; propagated from
                     UniProtKB/Swiss-Prot (P51114.3); acetylation site"
     misc_feature    415..585
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /note="Agenet domain; Region: Agenet; pfam05641"
                     /db_xref="CDD:191330"
     misc_feature    898..1080
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /note="K homology RNA-binding domain, type I.  KH binds
                     single-stranded RNA or DNA. It is found in a wide variety
                     of proteins including ribosomal proteins, transcription
                     factors and post-transcriptional modifiers of mRNA. There
                     are two different KH domains that...; Region: KH-I;
                     cd00105"
                     /db_xref="CDD:29002"
     misc_feature    order(922..924,928..936,940..954,961..966,973..978,
                     991..999)
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /note="nucleic acid binding region [nucleotide binding];
                     other site"
                     /db_xref="CDD:29002"
     misc_feature    943..954
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /note="G-X-X-G motif; other site"
                     /db_xref="CDD:29002"
     misc_feature    1096..1296
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /note="K homology RNA-binding domain, type I.  KH binds
                     single-stranded RNA or DNA. It is found in a wide variety
                     of proteins including ribosomal proteins, transcription
                     factors and post-transcriptional modifiers of mRNA. There
                     are two different KH domains that...; Region: KH-I;
                     cd00105"
                     /db_xref="CDD:29002"
     misc_feature    order(1111..1113,1117..1125,1129..1143,1150..1155,
                     1162..1167,1183..1194)
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /note="nucleic acid binding region [nucleotide binding];
                     other site"
                     /db_xref="CDD:29002"
     misc_feature    1132..1143
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /note="G-X-X-G motif; other site"
                     /db_xref="CDD:29002"
     misc_feature    1321..>1374
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /note="Fragile X-related 1 protein C terminal; Region:
                     FXR1P_C; pfam12235"
                     /db_xref="CDD:152670"
     misc_feature    1441..1443
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1447..1449
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1456..1458
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P51114.3); phosphorylation site"
     misc_feature    1456..1458
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1465..1467
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P51114.3); phosphorylation site"
     misc_feature    1465..1467
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1471..1473
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1477..1479
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1498..1500
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P51114.3); phosphorylation site"
     misc_feature    1507..1509
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P51114.3); phosphorylation site"
     misc_feature    1564..1611
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (P51114.3);
                     Region: RNA-binding RGG-box"
     misc_feature    1573..1575
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="methylation site"
     misc_feature    1597..1599
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="methylation site"
     misc_feature    1669..1671
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1693..1695
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P51114.3); phosphorylation site"
     misc_feature    1693..1695
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1702..1704
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1720..1722
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1999..2001
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P51114.3); phosphorylation site"
     misc_feature    2071..2073
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphothreonine; propagated from
                     UniProtKB/Swiss-Prot (P51114.3); phosphorylation site"
     variation       250
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:377637427"
     variation       267
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1805578"
     variation       276
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201247137"
     exon            292..344
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /inference="alignment:Splign:1.39.8"
     exon            345..438
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /inference="alignment:Splign:1.39.8"
     variation       364
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:375255336"
     variation       411
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371183000"
     exon            439..510
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /inference="alignment:Splign:1.39.8"
     variation       464
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199903473"
     variation       468
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144304502"
     exon            511..659
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /inference="alignment:Splign:1.39.8"
     variation       528
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145159450"
     variation       534
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:369357473"
     variation       627
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139008118"
     STS             628..742
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /standard_name="FXR1"
                     /db_xref="UniSTS:505522"
     STS             636..719
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /standard_name="RH123299"
                     /db_xref="UniSTS:135676"
     exon            660..753
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /inference="alignment:Splign:1.39.8"
     variation       702
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377389758"
     variation       708
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:3026195"
     exon            754..870
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /inference="alignment:Splign:1.39.8"
     variation       757
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:143250917"
     variation       766
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201512027"
     variation       813
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148268040"
     variation       861
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370062138"
     exon            871..1041
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /inference="alignment:Splign:1.39.8"
     variation       924
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374396414"
     variation       993
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:73176330"
     variation       1021
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200507471"
     variation       1027
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:142641159"
     exon            1042..1120
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /inference="alignment:Splign:1.39.8"
     variation       1062
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371122085"
     STS             1069..1275
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /standard_name="Fxr1h"
                     /db_xref="UniSTS:498301"
     variation       1096
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200358370"
     exon            1121..1230
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /inference="alignment:Splign:1.39.8"
     variation       1132
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:76531300"
     exon            1231..1317
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /inference="alignment:Splign:1.39.8"
     variation       1291
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:376660925"
     variation       1302
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1805617"
     exon            1318..1375
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /inference="alignment:Splign:1.39.8"
     variation       1329
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369969651"
     exon            1376..1438
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /inference="alignment:Splign:1.39.8"
     variation       1392
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202004870"
     variation       1431
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370623678"
     variation       1432
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372792772"
     exon            1439..1642
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /inference="alignment:Splign:1.39.8"
     variation       1448
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199510994"
     variation       1471
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199504601"
     variation       1472
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201616183"
     variation       1476
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200492892"
     variation       1525
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1051080"
     variation       1538
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371485992"
     variation       1547
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374389670"
     variation       1615
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199785386"
     exon            1643..1843
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /inference="alignment:Splign:1.39.8"
     variation       1649
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138120810"
     variation       1731
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201665512"
     variation       1736
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371778667"
     variation       1748
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143480969"
     STS             1836..2034
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /standard_name="BI281166"
                     /db_xref="UniSTS:249408"
     exon            1844..1935
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /inference="alignment:Splign:1.39.8"
     variation       1859
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377706871"
     variation       1884..1885
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:11435319"
     STS             1889..2093
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /standard_name="BI274570"
                     /db_xref="UniSTS:249125"
     variation       1892..1893
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:11435320"
     variation       1907
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201230703"
     variation       1925
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201838203"
     exon            1936..8567
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /inference="alignment:Splign:1.39.8"
     variation       1958
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147171380"
     variation       1959
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367886303"
     variation       1961
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:138367563"
     variation       1969
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149239435"
     variation       1971
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201161602"
     variation       1972
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111774718"
     variation       1991
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371671972"
     variation       1999
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201637634"
     variation       2008
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148795102"
     variation       2029
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:55637125"
     variation       2032
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:143951672"
     variation       2054
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:146350316"
     variation       2075
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:3026204"
     variation       2078
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:112134282"
     variation       2081
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11499"
     variation       2094
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:139713512"
     variation       2111
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376366097"
     variation       2116
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371231893"
     variation       2152
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199650094"
     variation       2193
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368937602"
     variation       2256
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:138323510"
     polyA_signal    2339..2344
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
     polyA_site      2367
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
     variation       2410
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:77451926"
     variation       2476
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:3026205"
     variation       2600
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372825020"
     variation       2607
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377201428"
     variation       2618
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:188550393"
     variation       2621
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:117037927"
     variation       2636
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191923790"
     variation       2823
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:145591161"
     variation       2888
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200701459"
     variation       2891..2892
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:201501227"
     variation       2892
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:138114654"
     variation       2901..2903
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace=""
                     /replace="ttt"
                     /db_xref="dbSNP:79881434"
     polyA_signal    2949..2954
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
     variation       2958
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:183311734"
     polyA_site      2976
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
     variation       3216..3217
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace=""
                     /replace="aa"
                     /db_xref="dbSNP:146154883"
     variation       3249..3250
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace=""
                     /replace="gg"
                     /db_xref="dbSNP:201594378"
     variation       3321
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:187223562"
     variation       3324
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:191718661"
     variation       3467
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:183888010"
     variation       3518
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:370717702"
     variation       3608
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:3026206"
     variation       3612
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113426020"
     variation       3657
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149096577"
     variation       3885
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:186780056"
     variation       3995..3996
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:35250215"
     variation       3996
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:67565008"
     variation       4015
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143130417"
     variation       4017
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1805627"
     variation       4031
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1805628"
     variation       4043
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:193140070"
     STS             4071..4232
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /standard_name="D3S2910E"
                     /db_xref="UniSTS:150894"
     variation       4105
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace=""
                     /replace="ta"
                     /db_xref="dbSNP:200214928"
     variation       4106..4107
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace=""
                     /replace="tt"
                     /db_xref="dbSNP:67477912"
     variation       4233
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:185723329"
     variation       4362
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:190201524"
     variation       4416
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:182067416"
     variation       4496
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148220661"
     variation       4576
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:62291435"
     variation       4606
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141181334"
     variation       4634
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:112349907"
     variation       4799
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:114145770"
     STS             4892..5042
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /standard_name="RH98363"
                     /db_xref="UniSTS:89700"
     variation       5031
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:184223404"
     variation       5048
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147356292"
     variation       5059
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:370998297"
     variation       5152
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1465374"
     variation       5160
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:188684032"
     variation       5224
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:3026207"
     variation       5247
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1008412"
     variation       5282
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1805629"
     STS             5291..5490
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /standard_name="D3S3105"
                     /db_xref="UniSTS:61824"
     STS             5296..5446
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /standard_name="Cda01e11"
                     /db_xref="UniSTS:64869"
     variation       5314
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374633367"
     variation       5343
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181123657"
     variation       5367
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:116043654"
     variation       5398
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:3026208"
     variation       5431
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:137877459"
     variation       5453
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:189429564"
     polyA_signal    5479..5484
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
     variation       5491
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:114677034"
     polyA_site      5510
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
     variation       5537
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:143392613"
     variation       5761
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:180725645"
     variation       5857
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147544455"
     variation       6009
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:187502719"
     STS             6026..6155
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /standard_name="A006P45"
                     /db_xref="UniSTS:58844"
     variation       6154
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1058382"
     variation       6156
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:6799476"
     variation       6198..6199
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:201242121"
     variation       6207
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:16832224"
     variation       6214..6215
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:144707771"
     variation       6266..6269
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace=""
                     /replace="atta"
                     /db_xref="dbSNP:373289717"
     variation       6268
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:3026209"
     variation       6282
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:191834999"
     variation       6337
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140179467"
     variation       6442
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183796587"
     variation       6464
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:79629055"
     variation       6492
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185999941"
     variation       6574
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373868693"
     variation       6575
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:190427919"
     variation       6692
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:150037153"
     variation       6742..6743
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:151155261"
     variation       6743..6744
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:11448946"
     variation       6807
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:182639763"
     variation       7025
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:7646508"
     variation       7155
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:368717976"
     variation       7190
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148748584"
     variation       7200
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1805630"
     variation       7251
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:202106534"
     variation       7318
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:142318810"
     variation       7322
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:187015735"
     variation       7347
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1805607"
     variation       7435
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:146809695"
     variation       7447
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:199927975"
     variation       7481
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:192718619"
     variation       7520
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:73046170"
     variation       7566
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201358029"
     variation       7611
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189118011"
     variation       7627
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1805631"
     variation       7657..7671
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace=""
                     /replace="tttacctggcttctg"
                     /db_xref="dbSNP:368024256"
     variation       7740
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:193073756"
     variation       7741
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1805632"
     variation       7837
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184439182"
     variation       7931
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369747203"
     variation       7980
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144198197"
     variation       8001
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:188933563"
     variation       8025
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:191855515"
     variation       8085
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1805633"
     variation       8109
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:117800767"
     STS             8122..8221
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /standard_name="SHGC-77579"
                     /db_xref="UniSTS:32551"
     STS             8123..8221
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /standard_name="G60386"
                     /db_xref="UniSTS:137492"
     variation       8151..8152
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2602"
     variation       8164
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:184031096"
     variation       8176
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2601"
     variation       8219
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368901111"
     variation       8227
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:76288512"
     variation       8252
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:189394362"
     variation       8339
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:62291436"
     variation       8385
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146531694"
     variation       8513
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11548477"
     polyA_signal    8545..8550
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
     polyA_site      8567
                     /gene="FXR1"
                     /gene_synonym="FXR1P"
ORIGIN      
aggcaaatccgacgtagacggcggcaggcggagcccaaagccggtgatgcagggtgcgcagggatcccacctggagagtcggggcggcacgttgagaccccaggggtgaagggcgggggatcccaatcccagccctgttttcccctcccctttccccgcctccttctcgcccctcccccctcctcccctctggttggaaagtttctagaatctcttcccagcggcctttgcggttccaacatggcggagctgacggtggaggttcgcggctctaacggggctttctacaagggatttatcaaagatgttcatgaagactcccttacagttgtttttgaaaataattggcaaccagaacgccaggttccatttaatgaagttagattaccaccaccacctgatataaaaaaagaaattagtgaaggagatgaagtagaggtatattcaagagcaaatgaccaagagccatgtgggtggtggttggctaaagttcggatgatgaaaggagaattttatgtcattgaatatgctgcttgtgacgctacttacaatgaaatagtcacatttgaacgacttcggcctgtcaatcaaaataaaactgtcaaaaaaaataccttctttaaatgcacagtggatgttcctgaggatttgagagaggcgtgtgctaatgaaaatgcacataaagattttaagaaagcagtaggagcatgcagaattttttaccatccagaaacaacacagctaatgatactgtctgccagtgaagcaactgtgaagagagtaaacatcttaagtgacatgcatttgcgaagtattcgtacgaagttgatgcttatgtccagaaatgaagaggccactaagcatttagaatgcacaaaacaacttgcagcagcttttcatgaggaatttgttgtgagagaagatttaatgggcctggcaataggaacacatggtagtaacatccagcaagctaggaaggttcctggagttaccgccattgagctagatgaagatactggaacattcagaatctacggagagagtgctgatgctgtaaaaaaggctagaggtttcttggaatttgtggaggattttattcaggttcctaggaatctcgttggaaaagtaattggaaaaaatggcaaagttattcaagaaatagtggacaaatctggtgtggttcgagtgagaattgaaggggacaatgaaaataaattacccagagaagacggtatggttccatttgtatttgttggcactaaagaaagcattggaaatgtgcaggttcttctagagtatcatattgcctatctaaaggaagtagaacagctaagaatggaacgcctacagattgatgaacagctgcgacagattggttctaggtcttatagcggaagaggcagaggtcgtcggggacctaattacacctccggttatggtacaaattctgagctgtctaacccctctgaaacggaatctgagcgtaaagacgagctgagtgattggtcattggcaggagaagatgatcgagacagccgacatcagcgtgacagcaggagacgcccaggaggaagaggcagaagtgtttcagggggtcgaggtcgtggtggaccacgtggtggcaaatcctccatcagttctgtgctcaaagatccagacagcaatccatacagcttacttgataatacagaatcagatcagactgcagacactgatgccagcgaatctcatcacagtactaaccgtcgtaggcggtctcgtagacgaaggactgatgaagatgctgttctgatggatggaatgactgaatctgatacagcttcagttaatgaaaatgggctagtcacagttgcagattatatttctagagctgagtctcagagcagacaaagaaacctcccaagggaaactttggctaaaaacaagaaagaaatggcaaaagatgtgattgaagagcatggtccttcagaaaaggcaataaacggcccaactagtgcttctggcgatgacatttctaagctacagcgtactccaggagaagaaaagattaataccttaaaagaagaaaacactcaagaagcagcagtcctgaatggtgtttcataaactgaagaagttcctagtttacagttcttttacattacatttacaatagtgcttgtacaagcttgccaaagatagaatatggatcgccagtctttacatcgcactttcagttcctccatttggaattcaaaaaggggagggatcctgaagaaatcatatgttaaacatactttgacacctactgtgttataaaatatatcatcagatgtgccttgagaatagtatatgtaacattaaaaaaaagttgctggctataggaaatgttattttgttttcaaaatatggcagagatggggggtggtgggtggggtgggatccctaacgtaatattctttatgaaagcattagctgcttttgttacatttttaatatgcaaccacttcttcacctgaggaaaactagaatgaaatgcagtctaaaatattttgcactgaattgtaatttcttcattagtttagtctggaaactggtctgttttaatgtgttttttaaatgctgtatgtagaggaaaatctgcagaccactggaatacatttgttaaactctcatctgcagggacactgggcgatacttggcagtgactgttctaccttgaggctttgtttggtttatttattaaagtgtacagtatttaaaaatcaaacatagctttagttaaaacactaagctgaattagtcatgtccattcagacataacctgaactactgaaaagatcaatttccagaaggtttattctgtataaactacatgttagtcttcagtagagtatcttttttttttccttttttttttttttatttcggttgtttgatgtgcaatatgtttttgtatgcaggtagtaaataaactttgatcttccatttgctgaatttttttaactttctactttttacaccaattgttgcaaaatagttggagctattaataggcttaggatagtatactttgctttttaaaaagcatttatacttgctcataaatagcattaaaatgtcagttggccatttaatcattttgtaatgaatcatctgaaatctttacacaagtttaggctgttagatgcataggtaattaataatacatgtgataattagcaaaaaaacctaacaaaattctaatcaaaggcaactttggaagacaatgggggatagaagggatgacaagcaatttttaaataataggccaatgatttgctttattcattctcaacttattttgaaggctctcatatcagtgaccaaaaatcagttattaaactttatgtatatattttagccagagcttaatttttatgaagataaagacatgaagtttaacaatggacaacagttagtacagctaattgtgaggtcaagtaattgttagacataggggaaggctttgttccacaatattatatggaccactgaacaagaatgacagccctttgttatcacttggcatatgaaaagtgttgtgtgcatagtttgtgttaattttttatgtgcataaaaatgtgattttaatttatatgctctgaaggataattcagggtatagttaaaaatgtacaatgtgccagttcagtatatataaccctagccctcaaattattctgattaaggttaaaatgtgctggtattacgtgctttttcctgaggccttctgattggttcttggtaacagaattttaaagtaaggtgtgagtagtgcaactcctgtcctttatatataaagatatcaagtaatttcatgtcctgatatttaaaaaaattacccacaaatgtgtttttttaaatcgatcaaagctagcaacaggttaaattgtctcagttctcttacataattgggttaaaaattataaggtattagaagaattttaattaatgccaaattggtaaatatggtgtaaaaaaaaaaaaaaagacttttcattttctcccacatagaatagtcagatatattaaacatcccttttccataaagatggtttcaatgggaatggaagaaacaaaatcttaaaagagtgagtatagctgaaccaattcttcattctagcaataaccacactaagttcattactttacaaatgactaaacccaatgtcttgtcctttaaaaaatataggtagtgcagaattgtgataaatacgcatttgtttttttagagagccccactccccaaagggtagccattaattcaggtagccttttaaatgtatttgagagggttccgtctttttggctgctatcctagttaggtgagatgttgctatgggaagaacttgccactatacactaaacagacacttaagcaaaagatgtattctggagcctggcacagtagcttatgtctttggttctagctactcaggagcctgaggtgggagcatcatttgaactcagttctgggccactgagaccctctttaaagagaaggaaaaaaaggtattctggaagatcttgtgcagttgcaacaatgtttcagcatatatatgtgaattcatatatgacacctgaacggaatcatgaagtaacagctgagattatatggtggcaaaaatgacctgcttttcctgaagctttgggaggcctaggattcttgctttaggcatcacctttgttaagccttaaagggggctacaacttgtgcaaaatggtgtctctggtaacacttcagaaataattggcaaaagtgtaataggaatacacaaatctttattttgaaataatcttgtattttaatgtggaattagaagcagcacatcaaactggtgagttcacagaaacttacctgagatgatgctgggttccattgctgttgtgctaagtcacgtatttttgtagctgctgttagctgtgtctagcgttttgtaacctaaggagggtcttatagaagttggtatgttaactaaatcttggactgggaaacagcaccatttgtatcctctgcaaacagatttacgcttttgaggctcaaaccaactagtgttctcatgggctgttgcctaaggacagataaacatggaaaacaggctatgtccagggacagatgattggtggttaagaattacagtaaaggaaaattacacctggattttcttctgtaaagtttcaaggaacttggatttgaactgtgaatctactgttttggcaaaaaatctcaaagaaaaggatgtttgttactgtctcagtcttcctgtctttgctacacgatttggatcccttacgctttttcgttaagaatatctgtctgctatagtgaatttgctagccccttatttttttttttaattttagttctttattagaacgtgtacttgaatggactgtagttgctcataacccatgttaatctctgatagtatttgggttttatttcaggagcttttgcaataaagcagtaactgcaatctgctaaagtcagactgttagcaagtggtgttaaaactgatttaagtccattacactgaacagtaggaaattaccacttttgtaaggctcaaaaatgatcaactattaacagtttcttatggttcagtctaattacaaatttttaaaaagtttatcagtgtatcatttcagattcatctgtatcttctgtaatattatttccagtactgaggtaaggtacacaaaaattcccctggaaaaactatattctagttttgtaagatgatttcccacagtccatttgcttatttcttcctttgataattcaaaaagatgctttaggtaatggtacagaattagaagctgctattttagctctattaactttttctctatggtttcaattttatccaaccagagagggctggcctagttggtatctttaaggcccttccagtagtaatttgagtctagtcacatgtcagaccctgagcaacacctaaccaaatgcccaagtattctcataaggagtatgctgaatttaagtggtgtttgttttacatatgtatccatcccagacattttcaactatgctgaatgcaatctataagatattccaaacaaggacaaagtaatttttcacaagtcttacagccccactattaagtatgctactaattagcttcttgaatttctttgtatttcagtgattgggatgttctttttttttgggaaagtttttttacccctttgtaccctcttaattggattaactgtaaaatgtacatattaattttctagttttagagaccattttcattaaaaatattttccaatagtttttctagataaacaatttatacttaattgttgcttggttgcttacatttcaacctctaggcttcctttttcagctaacttggctgtcttcaggttgtaaagaaaaatgtaaacatatatttgaaatttcattaactgaaactgctgtaaggtgttagcaaatgttaaccataacagattatcccatatcattggactgttctattattgggtcaggaataataggtgacacaggatagaagctcttcctatatatatcttgttgctaaggcagtagttggctctaagctgataaacagcacactgtacagcagtccaaaaactaaaaccagagcttaggtcattcaagttaactggtactcaaggttactcattccaggatactttacataaccaaaaacctaggagagcattctacattgtaattttttttttactttgtttacataaaatttacagggttttgtttttttaagcttagtctgttctttgacattgttgattcatgttctaaattttcatcagatttaacatgtttggaggttcttgtgcactcaatgtgaacctactacaagcttctgaactgcaaaaccttttttttaggtcactgtcaacagaaagatgccttatagaatttctcatgattgaaacagaactctgcattctaacctaaaacccctctaaccctttaaatgaagcattatgcctgcgtgaaattttatttttagacatttctgatactaggttttctttacgggggggcatacatattcagtatactgaatttatacagctttcagtgtggcaatatattaagaagctagttccctaatttttctcagttctcattggttttccatttaaatgtttccgtaagtactctcatcatttggaaaatacttgatggcaggagaacttgcttaaaactaaaggtggagaaagagttaacttccaggacaacccattatagctcacttcttaccaacaaagcagtttttatacagcaccttaggactcatttctaatgtcaacccagatggccagtaaaggcaagggaagaggctaagtgactcacaaaaatctctgatattgaggtctaatgtgaaggctatagataggaattccccacaaacttctaatgaggactaatatgaacagcaaattggagaagacaccaaggacctaattttagtttcactagccgtgggaccttagaaaaaagaccatttgctctggacttttgtttcccaagccataaaatgtggaagaatcttcacaatttcaagttggtcatgtatatttcccttttacagagaaagctgaagcctcgaggctcagatttacctggcttctgtttacctggcttctgcagaagtttaacttgtaacctacctctcattcccaaagtgtgtttaatcatgccgccttctttaaaatatatctggaagcaccaatgagtaaagacaaaggccccaagctagatctgtagagataagtactagactcacatctcagtactatcaaggaaaacatgcttaggttatcagaattgtgaaggccatagtacaaaaagttaagagaacggaactcaggatctgagaaagatcagccattctcagcatgttgccttggctgcttaaccttactaaacttccatttcctcacatgtaaaatgtacatcataataactagtctactgagataagggaagaatacttagcacagtgctagtacactgtaagtactcaaatgttacagatccaagtattttgtaagaaaataccagcaaaagataaaagtttttttatggatcgtatttgtatcaatcacctacatgatctagagccctcacatggataacatttaaatgttcagtttgcctaatagccttcaatgaaacacggattcttctacttaaaaaaggtaagcctggagaaaataaaactgattactatgcaagaaaaaaatgtgctctgctgtgctccttggtatttttaagtggtttccattgtcttaacacctgtcttaaaacgggtatgttgtttgcactgaaccctcaaaagtatttatacctattaagttaaatttccctttttagagttaatgcttcattgcctgtcggcatattatcactatctgtctttgaaaaattttcttttaagtctcaactatttcttcataaagctcttgttcagagaaacattttttgatttgtccaatggactgaaataaaaggttagtaaaccaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:8087 -> Molecular function: GO:0002151 [G-quadruplex RNA binding] evidence: IEA
            GeneID:8087 -> Molecular function: GO:0003723 [RNA binding] evidence: TAS
            GeneID:8087 -> Molecular function: GO:0003730 [mRNA 3'-UTR binding] evidence: IEA
            GeneID:8087 -> Biological process: GO:0006915 [apoptotic process] evidence: TAS
            GeneID:8087 -> Biological process: GO:0007517 [muscle organ development] evidence: IEA
            GeneID:8087 -> Biological process: GO:0017148 [negative regulation of translation] evidence: IEA
            GeneID:8087 -> Biological process: GO:0030154 [cell differentiation] evidence: IEA
            GeneID:8087 -> Cellular component: GO:0005730 [nucleolus] evidence: TAS
            GeneID:8087 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
            GeneID:8087 -> Cellular component: GO:0005844 [polysome] evidence: IEA
            GeneID:8087 -> Cellular component: GO:0043034 [costamere] evidence: IEA

by @meso_cacase at DBCLS
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