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2024-04-25 04:04:36, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_004879 2279 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens etoposide induced 2.4 (EI24), transcript variant 1,
mRNA.
ACCESSION NM_004879
VERSION NM_004879.3 GI:55956765
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2279)
AUTHORS Mazumder Indra,D., Mitra,S., Singh,R.K., Dutta,S., Roy,A.,
Mondal,R.K., Basu,P.S., Roychoudhury,S. and Panda,C.K.
TITLE Inactivation of CHEK1 and EI24 is associated with the development
of invasive cervical carcinoma: clinical and prognostic
implications
JOURNAL Int. J. Cancer 129 (8), 1859-1871 (2011)
PUBMED 21154811
REMARK GeneRIF: our data suggest that inactivation of EI24 and CHEK1
through two independent mechanisms contributes to the development
of CACX.
REFERENCE 2 (bases 1 to 2279)
AUTHORS Sinha,S., Singh,R.K., Bhattacharya,N., Mukherjee,N., Ghosh,S.,
Alam,N., Roy,A., Roychoudhury,S. and Panda,C.K.
TITLE Frequent alterations of LOH11CR2A, PIG8 and CHEK1 genes at
chromosomal 11q24.1-24.2 region in breast carcinoma: clinical and
prognostic implications
JOURNAL Mol Oncol 5 (5), 454-464 (2011)
PUBMED 21803008
REMARK GeneRIF: LOH11CR2A, PIG8 and CHEK1 are candidate tumor suppressor
genes associated with breast carcinoma and have significant
clinical as well as prognostic importance.
REFERENCE 3 (bases 1 to 2279)
AUTHORS Mork,C.N., Faller,D.V. and Spanjaard,R.A.
TITLE Loss of putative tumor suppressor EI24/PIG8 confers resistance to
etoposide
JOURNAL FEBS Lett. 581 (28), 5440-5444 (2007)
PUBMED 17981155
REMARK GeneRIF: identify the EI24/PIG8 status as a potentially new
prognostic marker of chemotherapy responsiveness
REFERENCE 4 (bases 1 to 2279)
AUTHORS Gentile,M., Ahnstrom,M., Schon,F. and Wingren,S.
TITLE Candidate tumour suppressor genes at 11q23-q24 in breast cancer:
evidence of alterations in PIG8, a gene involved in p53-induced
apoptosis
JOURNAL Oncogene 20 (53), 7753-7760 (2001)
PUBMED 11753653
REFERENCE 5 (bases 1 to 2279)
AUTHORS Burns,T.F., Bernhard,E.J. and El-Deiry,W.S.
TITLE Tissue specific expression of p53 target genes suggests a key role
for KILLER/DR5 in p53-dependent apoptosis in vivo
JOURNAL Oncogene 20 (34), 4601-4612 (2001)
PUBMED 11498783
REFERENCE 6 (bases 1 to 2279)
AUTHORS Gu,Z., Flemington,C., Chittenden,T. and Zambetti,G.P.
TITLE ei24, a p53 response gene involved in growth suppression and
apoptosis
JOURNAL Mol. Cell. Biol. 20 (1), 233-241 (2000)
PUBMED 10594026
REFERENCE 7 (bases 1 to 2279)
AUTHORS Gu,Z., Gilbert,D.J., Valentine,V.A., Jenkins,N.A., Copeland,N.G.
and Zambetti,G.P.
TITLE The p53-inducible gene EI24/PIG8 localizes to human chromosome
11q23 and the proximal region of mouse chromosome 9
JOURNAL Cytogenet. Cell Genet. 89 (3-4), 230-233 (2000)
PUBMED 10965130
REFERENCE 8 (bases 1 to 2279)
AUTHORS Polyak,K., Xia,Y., Zweier,J.L., Kinzler,K.W. and Vogelstein,B.
TITLE A model for p53-induced apoptosis
JOURNAL Nature 389 (6648), 300-305 (1997)
PUBMED 9305847
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BM450796.1, AP001494.4,
BC002390.2, BM467354.1 and BQ936285.1.
This sequence is a reference standard in the RefSeqGene project.
On Nov 22, 2004 this sequence version replaced gi:6631103.
Summary: This gene has higher expression in p53-expressing cells
than in control cells and is an immediate-early induction target of
p53-mediated apoptosis. The protein encoded by this gene contains
six putative transmembrane domains and may suppress cell growth by
inducing apoptotic cell death through the caspase 9 and
mitochondrial pathways. This gene is located on human chromosome
11q24, a region frequently altered in cancers. Alternative splicing
results in two transcript variants encoding different isoforms.
[provided by RefSeq, Jul 2008].
Transcript Variant: This variant (1) encodes the longest isoform
(1).
##Evidence-Data-START##
Transcript exon combination :: AF010313.2, AB209820.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025082 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-6 BM450796.1 1-6
7-126 AP001494.4 26770-26889
127-1844 BC002390.2 8-1725
1845-2060 BM467354.1 156-371
2061-2279 BQ936285.1 212-430
FEATURES Location/Qualifiers
source 1..2279
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="11"
/map="11q24"
gene 1..2279
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/note="etoposide induced 2.4"
/db_xref="GeneID:9538"
/db_xref="HGNC:13276"
/db_xref="MIM:605170"
exon 1..172
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/inference="alignment:Splign:1.39.8"
variation 95
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:368693305"
variation 126
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:3017281"
exon 173..284
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/inference="alignment:Splign:1.39.8"
variation 192
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:376955676"
variation 210
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="g"
/db_xref="dbSNP:369395580"
misc_feature 225..227
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/note="upstream in-frame stop codon"
variation 242
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:190131090"
CDS 243..1265
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/note="isoform 1 is encoded by transcript variant 1; tumor
protein p53 inducible protein 8; ectopic P-granules
autophagy protein 4 homolog; etoposide-induced protein 2.4
homolog; etoposide induced 2.4 mRNA; p53-induced gene 8
protein"
/codon_start=1
/product="etoposide-induced protein 2.4 homolog isoform 1"
/protein_id="NP_004870.3"
/db_xref="GI:55956766"
/db_xref="GeneID:9538"
/db_xref="HGNC:13276"
/db_xref="MIM:605170"
/translation="
MADSVKTFLQDLARGIKDSIWGICTISKLDARIQQKREEQRRRRASSVLAQRRAQSIERKQESEPRIVSRIFQCCAWNGGVFWFSLLLFYRVFIPVLQSVTARIIGDPSLHGDVWSWLEFFLTSIFSALWVLPLFVLSKVVNAIWFQDIADLAFEVSGRKPHPFPSVSKIIADMLFNLLLQALFLIQGMFVSLFPIHLVGQLVSLLHMSLLYSLYCFEYRWFNKGIEMHQRLSNIERNWPYYFGFGLPLAFLTAMQSSYIISGCLFSILFPLFIISANEAKTPGKAYLFQLRLFSLVVFLSNRLFHKTVYLQSALSSSTSAEKFPSPHPSPAKLKATAGH
"
misc_feature 408..410
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(O14681.4); phosphorylation site"
misc_feature 408..410
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 435..1007
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/note="Etoposide-induced protein 2.4 (EI24); Region: EI24;
pfam07264"
/db_xref="CDD:203606"
misc_feature 471..533
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (O14681.4);
transmembrane region"
misc_feature 591..653
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (O14681.4);
transmembrane region"
misc_feature 777..839
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (O14681.4);
transmembrane region"
misc_feature 954..1007
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (O14681.4);
transmembrane region"
misc_feature 1011..1073
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (O14681.4);
transmembrane region"
misc_feature 1218..1220
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(O14681.4); phosphorylation site"
misc_feature 1218..1220
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1230..1232
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(O14681.4); phosphorylation site"
misc_feature 1230..1232
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
variation 271
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:377285559"
variation 273
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="g"
/replace="t"
/db_xref="dbSNP:371166633"
exon 285..430
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/inference="alignment:Splign:1.39.8"
variation 343
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:11538202"
variation 363
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:143089007"
variation 390
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:373668336"
variation 402
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="g"
/db_xref="dbSNP:1043914"
variation 417
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:187402952"
exon 431..491
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/inference="alignment:Splign:1.39.8"
variation 438
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:368526220"
exon 492..558
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/inference="alignment:Splign:1.39.8"
variation 539
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:372011817"
variation 557
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:375565019"
exon 559..683
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/inference="alignment:Splign:1.39.8"
variation 569
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="t"
/db_xref="dbSNP:374580824"
variation 590
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:140296039"
variation 598
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:1043918"
variation 627
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="g"
/db_xref="dbSNP:1043919"
exon 684..803
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/inference="alignment:Splign:1.39.8"
variation 710
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="t"
/db_xref="dbSNP:372628822"
variation 728
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:373755758"
variation 741
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:199956275"
variation 767
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:371367478"
exon 804..915
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/inference="alignment:Splign:1.39.8"
STS 825..1097
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/standard_name="RH64693"
/db_xref="UniSTS:82304"
variation 839
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:117877629"
variation 840
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:373773329"
variation 899
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:376206953"
exon 916..1027
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/inference="alignment:Splign:1.39.8"
variation 948
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:3017282"
variation 1018
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:372602233"
exon 1028..1102
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/inference="alignment:Splign:1.39.8"
variation 1070
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:201075869"
variation 1086..1087
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace=""
/replace="c"
/db_xref="dbSNP:55912941"
variation 1100
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:4627097"
exon 1103..2262
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/inference="alignment:Splign:1.39.8"
variation 1106
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:77420108"
variation 1116
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:371275461"
STS 1157..1246
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/standard_name="D11S2234E"
/db_xref="UniSTS:78001"
variation 1180
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:373537623"
variation 1181
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:201184433"
variation 1197
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:375652371"
variation 1204
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:368640507"
variation 1223
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:377515763"
variation 1228
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:371870792"
variation 1229
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:201282432"
variation 1232
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:368076474"
variation 1249
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:371540566"
variation 1308
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:375171251"
variation 1314..1315
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace=""
/replace="g"
/db_xref="dbSNP:370012892"
variation 1428
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="g"
/db_xref="dbSNP:375102205"
variation 1474
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="c"
/db_xref="dbSNP:12417397"
variation 1477
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:188509727"
variation 1504
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:12420149"
variation 1517
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:12420150"
STS 1535..1634
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/standard_name="2002"
/db_xref="UniSTS:22085"
variation 1561
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="g"
/replace="t"
/db_xref="dbSNP:11538203"
variation 1577
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:7094"
variation 1608
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:12420174"
variation 1639
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="t"
/db_xref="dbSNP:374416673"
variation 1683
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="t"
/db_xref="dbSNP:139180334"
variation 1717
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:191258397"
variation 1761
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="c"
/replace="g"
/db_xref="dbSNP:149952907"
variation 1807
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="c"
/db_xref="dbSNP:1044048"
variation 1840..1844
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace=""
/replace="ttt"
/replace="ttttt"
/db_xref="dbSNP:71045108"
variation 1844
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace=""
/replace="aaaa"
/replace="aaaaaaaaa"
/db_xref="dbSNP:56843571"
variation 2061
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="g"
/db_xref="dbSNP:139643050"
STS 2077..2218
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/standard_name="STS-T46944"
/db_xref="UniSTS:15560"
variation 2132
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
/replace="a"
/replace="t"
/db_xref="dbSNP:1062795"
polyA_signal 2240..2245
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
polyA_site 2264
/gene="EI24"
/gene_synonym="EPG4; PIG8; TP53I8"
ORIGIN
ccccgcctcgtggtgccggctggttcttcgcgctcgcccgacttcccagcggccccgtgcggcccgggcatgcccagtgcgggcgcagcggccccggccctggaagcgccccggcggagctggcctgcggtgggctaggggcagggccggagccgcggcggcggagctgtggatccttcatgatgagagatttggggacacttctctctcctgtgtgtagttgatagtttggtggtgaagagatggctgacagtgtcaaaacctttctccaggaccttgccagaggaatcaaagactccatctggggtatttgtaccatctcaaagctagatgctcgaatccagcaaaagagagaggagcagcgtcgaagaagggcaagtagtgtcttggcacagagaagagcccagagtatagagcggaagcaagagagtgagccacgtattgttagtagaattttccagtgttgtgcttggaatggtggagtgttctggttcagtctcctcttgttttatcgagtatttattcctgtgcttcagtcggtaacagcccgaattatcggtgacccatcactacatggagatgtttggtcgtggctggaattcttcctcacgtcaattttcagtgctctttgggtgctccccttgtttgtgcttagcaaagtggtgaatgccatttggtttcaggatatagctgacctggcatttgaggtatcagggaggaagcctcacccattccctagtgtcagcaaaataattgctgacatgctcttcaaccttttgctgcaggctcttttcctcattcagggaatgtttgtgagtctctttcccatccatcttgtcggtcagctggttagtctcctgcatatgtcccttctctactcactgtactgctttgaatatcgttggttcaataaaggaattgaaatgcaccagcggttgtctaacatagaaaggaattggccttactactttgggtttggtttgcccttggcttttctcacagcaatgcagtcctcatatattatcagtggctgccttttctctatcctctttcctttattcattatcagcgccaatgaagcaaagacccctggcaaagcatatctcttccagttgcgcctcttctccttggtggtcttcttaagcaacagactcttccacaagacagtctacctgcagtcggccctgagcagctctacttctgcagagaagttcccttcaccgcatccgtcgcctgccaaactgaaggctactgcaggtcactgagttgcctgccatccaaaggggatgggcgggattggaagaagctgtggcagctcttttccctgttcacctcccgcctgccagggaaggcaggacccgctctgccaagggccctctgcgtattcccttctctctgaggaattgaaatttttgtctctggtgcacgtaaggcagaatgttccctgacaccagtgtgtggatttttaacatcaccgtgagtctgaaaggaccacaggtttttctgcagctattttctagcatttgccagtccctgtgcctggactgattggaacactttgtttttctccctgtgccatttacccttccacctttccatcctgccttctaccacccttggatgaatggattttgtaattctagctgttgtattttgtgaatttgttaattttgttgtttttctgtgaaacacatacattggatatgggaggtaaaggagtgtcccagttgctcctggtcactccctttatagccattactgtcttgtttcttgtaactcaggttaggttttggtctctcttgctccactgcaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaagcctgaagagatgagataggaggaaagacctcacagccagatctgctgggttttgaggagtgattttctttcttccccttgaaggggaaaaagctattttcattggtacatttaaagtcccccaactatggggaggtaccaattctggacaagtgccactacaacaacactaaacctgaacttttcaactccgttggtggtgggaggcagcgggcagaaatttactgttggccactgccaggtctatttcatatttcaaaggaatattgggtgctgcatataggaactgaaggggtcaatgtattaaacctgtgattggttgttttcctgtcattttgagagactaaatgtggggggcagatgtcaaaatacctgtacaattttaaaatgtcacaattaaacatgagctggtttcccaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:9538 -> Biological process: GO:0006914 [autophagy] evidence: IEA
GeneID:9538 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:9538 -> Biological process: GO:0006917 [induction of apoptosis] evidence: IEA
GeneID:9538 -> Biological process: GO:0030308 [negative regulation of cell growth] evidence: IDA
GeneID:9538 -> Biological process: GO:0042493 [response to drug] evidence: IEA
GeneID:9538 -> Cellular component: GO:0005789 [endoplasmic reticulum membrane] evidence: IEA
GeneID:9538 -> Cellular component: GO:0016021 [integral to membrane] evidence: IEA
GeneID:9538 -> Cellular component: GO:0031965 [nuclear membrane] evidence: IEA
by
@meso_cacase at
DBCLS
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