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2024-04-18 13:36:09, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_004783 4679 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens TAO kinase 2 (TAOK2), transcript variant 2, mRNA.
ACCESSION NM_004783
VERSION NM_004783.3 GI:354721193
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4679)
AUTHORS de Anda,F.C., Rosario,A.L., Durak,O., Tran,T., Graff,J.,
Meletis,K., Rei,D., Soda,T., Madabhushi,R., Ginty,D.D.,
Kolodkin,A.L. and Tsai,L.H.
TITLE Autism spectrum disorder susceptibility gene TAOK2 affects basal
dendrite formation in the neocortex
JOURNAL Nat. Neurosci. 15 (7), 1022-1031 (2012)
PUBMED 22683681
REMARK GeneRIF: TAOK2 is essential for dendrite morphogenesis; TAOK2
downregulation impairs basal dendrite formation without affecting
apical dendrites.
Publication Status: Online-Only
REFERENCE 2 (bases 1 to 4679)
AUTHORS Kumar,R.A., Marshall,C.R., Badner,J.A., Babatz,T.D., Mukamel,Z.,
Aldinger,K.A., Sudi,J., Brune,C.W., Goh,G., Karamohamed,S.,
Sutcliffe,J.S., Cook,E.H., Geschwind,D.H., Dobyns,W.B.,
Scherer,S.W. and Christian,S.L.
TITLE Association and mutation analyses of 16p11.2 autism candidate genes
JOURNAL PLoS ONE 4 (2), E4582 (2009)
PUBMED 19242545
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 3 (bases 1 to 4679)
AUTHORS Raman,M., Earnest,S., Zhang,K., Zhao,Y. and Cobb,M.H.
TITLE TAO kinases mediate activation of p38 in response to DNA damage
JOURNAL EMBO J. 26 (8), 2005-2014 (2007)
PUBMED 17396146
REFERENCE 4 (bases 1 to 4679)
AUTHORS Zihni,C., Mitsopoulos,C., Tavares,I.A., Baum,B., Ridley,A.J. and
Morris,J.D.
TITLE Prostate-derived sterile 20-like kinase 1-alpha induces apoptosis.
JNK- and caspase-dependent nuclear localization is a requirement
for membrane blebbing
JOURNAL J. Biol. Chem. 282 (9), 6484-6493 (2007)
PUBMED 17158878
REMARK GeneRIF: PSK1-alpha is a bifunctional kinase that associates with
microtubules, and JNK- and caspase-mediated removal of its
C-terminal microtubule-binding domain permits nuclear translocation
of the N-terminal region of PSK1-alpha and its induction of
apoptosis
REFERENCE 5 (bases 1 to 4679)
AUTHORS Huangfu,W.C., Omori,E., Akira,S., Matsumoto,K. and
Ninomiya-Tsuji,J.
TITLE Osmotic stress activates the TAK1-JNK pathway while blocking
TAK1-mediated NF-kappaB activation: TAO2 regulates TAK1 pathways
JOURNAL J. Biol. Chem. 281 (39), 28802-28810 (2006)
PUBMED 16893890
REMARK GeneRIF: the TAK1-JNK pathway is activated by osmotic stress, while
blocking TAK1-mediated NF-kappaB activation; TAO2 regulates TAK1
pathways
REFERENCE 6 (bases 1 to 4679)
AUTHORS Nakayama,M., Kikuno,R. and Ohara,O.
TITLE Protein-protein interactions between large proteins: two-hybrid
screening using a functionally classified library composed of long
cDNAs
JOURNAL Genome Res. 12 (11), 1773-1784 (2002)
PUBMED 12421765
REFERENCE 7 (bases 1 to 4679)
AUTHORS Chen,Z. and Cobb,M.H.
TITLE Regulation of stress-responsive mitogen-activated protein (MAP)
kinase pathways by TAO2
JOURNAL J. Biol. Chem. 276 (19), 16070-16075 (2001)
PUBMED 11279118
REFERENCE 8 (bases 1 to 4679)
AUTHORS Moore,T.M., Garg,R., Johnson,C., Coptcoat,M.J., Ridley,A.J. and
Morris,J.D.
TITLE PSK, a novel STE20-like kinase derived from prostatic carcinoma
that activates the c-Jun N-terminal kinase mitogen-activated
protein kinase pathway and regulates actin cytoskeletal
organization
JOURNAL J. Biol. Chem. 275 (6), 4311-4322 (2000)
PUBMED 10660600
REFERENCE 9 (bases 1 to 4679)
AUTHORS Chen,Z., Hutchison,M. and Cobb,M.H.
TITLE Isolation of the protein kinase TAO2 and identification of its
mitogen-activated protein kinase/extracellular signal-regulated
kinase kinase binding domain
JOURNAL J. Biol. Chem. 274 (40), 28803-28807 (1999)
PUBMED 10497253
REFERENCE 10 (bases 1 to 4679)
AUTHORS Hutchison,M., Berman,K.S. and Cobb,M.H.
TITLE Isolation of TAO1, a protein kinase that activates MEKs in
stress-activated protein kinase cascades
JOURNAL J. Biol. Chem. 273 (44), 28625-28632 (1998)
PUBMED 9786855
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BP233788.1, BC152413.1,
AF263313.1, CN286840.1 and AI805725.1.
This sequence is a reference standard in the RefSeqGene project.
On Oct 29, 2011 this sequence version replaced gi:45505128.
Summary: This gene encodes a serine/threonine protein kinase that
is involved in many different processes, including, cell signaling,
microtubule organization and stability, and apoptosis.
Alternatively spliced transcript variants encoding different
isoforms have been described for this gene. [provided by RefSeq,
Oct 2011].
Transcript Variant: This variant (2) contains alternate exons at
the 3' end compared to variant 1. This results in a shorter isoform
(2, also known as PSK1-beta) with a distinct C-terminus compared to
isoform 1.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC152413.1, AB020688.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025082 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-414 BP233788.1 2-415
415-2175 BC152413.1 1-1761
2176-3201 AF263313.1 1359-2384
3202-4153 BC152413.1 2788-3739
4154-4533 CN286840.1 44-423
4534-4679 AI805725.1 1-146 c
FEATURES Location/Qualifiers
source 1..4679
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="16"
/map="16p11.2"
gene 1..4679
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/note="TAO kinase 2"
/db_xref="GeneID:9344"
/db_xref="HGNC:16835"
/db_xref="HPRD:18147"
/db_xref="MIM:613199"
exon 1..782
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
variation 26..27
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace=""
/replace="gggaga"
/db_xref="dbSNP:369424505"
variation 94
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="g"
/db_xref="dbSNP:372412751"
variation 385
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:144553970"
variation 390
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:190480473"
variation 442
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:139619931"
variation 507
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="g"
/replace="t"
/db_xref="dbSNP:145501593"
variation 761
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370358920"
misc_feature 770..772
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/note="upstream in-frame stop codon"
exon 783..949
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
CDS 818..3967
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/EC_number="2.7.11.1"
/note="isoform 2 is encoded by transcript variant 2;
prostate derived STE20-like kinase PSK;
serine/threonine-protein kinase TAO2; PSK-1; hKFC-C;
kinase from chicken homolog C; prostate-derived STE20-like
kinase 1; prostate-derived sterile 20-like kinase 1;
thousand and one amino acid protein kinase 2"
/codon_start=1
/product="serine/threonine-protein kinase TAO2 isoform 2"
/protein_id="NP_004774.1"
/db_xref="GI:4759208"
/db_xref="CCDS:CCDS10662.1"
/db_xref="GeneID:9344"
/db_xref="HGNC:16835"
/db_xref="HPRD:18147"
/db_xref="MIM:613199"
/translation="
MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDAVRELDNLQYRKMKKILFQEAPNGPGAEAPEEEEEAEPYMHRAGTLTSLESSHSVPSMSISASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHSSIIHRLPGSDNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTASLVSRQIQEHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRAGFGAEAEKLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQLKEELQENPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLARHSLDQDLLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTELGNQLEYNKRREQELRQKHAAQVRQQPKSLKSKELQIKKQFQETCKIQTRQYKALRAHLLETTPKAQHKSLLKRLKEEQTRKLAILAEQYDQSISEMLSSQALRLDETQEAEFQALRQQLQQELELLNAYQSKIKIRTESQHERELRELEQRVALRRALLEQRVEEELLALQTGRSERIRSLLERQAREIEAFDAESMRLGFSSMALGGIPAEAAAQGYPAPPPAPAWPSRPVPRSGAHWSHGPPPPGMPPPAWRQPSLLAPPGPPNWLGPPTQSGTPRGGALLLLRNSPQPLRRAASGGSGSENVGPPAAAVPGPLSRSTSVASHILNGSSHFYS
"
misc_feature 842..844
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UL54.2); phosphorylation site"
misc_feature 851..1771
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/note="Catalytic domain of the Protein Serine/Threonine
Kinase, Thousand-and-one amino acids proteins; Region:
STKc_TAO; cd06607"
/db_xref="CDD:132938"
misc_feature 899..1660
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/note="Serine/Threonine protein kinases, catalytic domain;
Region: S_TKc; smart00220"
/db_xref="CDD:197582"
misc_feature order(917..931,941..943,980..982,986..988,1082..1084,
1130..1141,1145..1150,1157..1159,1268..1270,1274..1285,
1289..1291,1322..1324,1331..1333,1361..1372,1376..1378,
1466..1468,1493..1495,1757..1759)
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/note="active site"
/db_xref="CDD:132938"
misc_feature order(917..931,941..943,980..982,986..988,1082..1084,
1130..1141,1145..1150,1157..1159,1280..1285,1289..1291,
1322..1324,1757..1759)
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:132938"
misc_feature order(926..931,1268..1270,1274..1282,1331..1333,
1361..1372,1376..1378,1466..1468,1493..1495)
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:132938"
misc_feature 1319..1378
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/note="activation loop (A-loop); other site"
/db_xref="CDD:132938"
misc_feature 1358..1360
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UL54.2); phosphorylation site"
misc_feature 2273..2275
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UL54.2); phosphorylation site"
variation 833
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:146116179"
variation 940
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:56357942"
exon 950..1021
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
variation 997
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:200753196"
variation 1015
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201542476"
exon 1022..1123
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
variation 1068
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150712108"
variation 1093
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:61737959"
variation 1102
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373920588"
variation 1117
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368062779"
exon 1124..1169
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
exon 1170..1266
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
variation 1213
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:149481071"
variation 1216
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:375813642"
variation 1228
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:144361133"
exon 1267..1380
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
variation 1336
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201648224"
variation 1356
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140117945"
exon 1381..1472
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
variation 1390
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372951562"
variation 1438
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:377056032"
variation 1439
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375334553"
exon 1473..1566
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
variation 1544
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:143934788"
variation 1552
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:146397844"
exon 1567..1648
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
variation 1591
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:139742949"
variation 1594
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="c"
/db_xref="dbSNP:142801026"
variation 1596
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373914698"
variation 1604
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="g"
/db_xref="dbSNP:200074622"
variation 1606..1607
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace=""
/replace="a"
/db_xref="dbSNP:35185276"
variation 1638
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:151026108"
exon 1649..1816
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
variation 1664
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141012429"
variation 1685
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:149797802"
variation 1694
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:56266215"
variation 1717
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:145019528"
variation 1762
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:370365042"
variation 1783
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:199673794"
exon 1817..2077
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
variation 1822
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:55903157"
variation 1826
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368342001"
variation 1832
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371958190"
variation 1849
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:376880756"
variation 1885
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:75361745"
variation 1908
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:145917075"
variation 1912
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="c"
/db_xref="dbSNP:372509673"
variation 1918
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:138953442"
variation 1919
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375972588"
variation 1948
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:61738514"
variation 1955..1957
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace=""
/replace="gag"
/db_xref="dbSNP:368747234"
variation 2007
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376173807"
variation 2017
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201815164"
variation 2018
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:35174880"
variation 2021
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="t"
/db_xref="dbSNP:377201939"
variation 2029
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="g"
/db_xref="dbSNP:143466363"
variation 2038
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:369607203"
variation 2064
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:78058418"
variation 2069
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:182132470"
exon 2078..2239
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
variation 2092
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="t"
/db_xref="dbSNP:147979834"
variation 2139
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:371609102"
variation 2140
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:61739161"
variation 2148
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:150531888"
variation 2165
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:138564043"
variation 2176
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:3814883"
variation 2187..2189
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace=""
/replace="ggg"
/db_xref="dbSNP:370085614"
variation 2193
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="c"
/db_xref="dbSNP:74981424"
variation 2199
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:146348272"
variation 2205
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:139763660"
variation 2230
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:61737875"
exon 2240..2605
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
variation 2296
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:55656713"
variation 2340
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="g"
/db_xref="dbSNP:200883075"
variation 2368
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:55679005"
variation 2389
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:79799790"
variation 2393
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:376299348"
variation 2394
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:142369950"
variation 2407
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:147907995"
variation 2411
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373048486"
variation 2450
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="c"
/db_xref="dbSNP:376979156"
variation 2494
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:56312054"
variation 2501
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:371473286"
variation 2527
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200156226"
variation 2552
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141623258"
variation 2580
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373817628"
exon 2606..2809
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
variation 2680
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:144417212"
variation 2691
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:61737877"
variation 2704
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="c"
/db_xref="dbSNP:376415632"
variation 2708
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="g"
/db_xref="dbSNP:141485756"
variation 2755
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:150370002"
variation 2770
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:113762295"
variation 2773
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:202213283"
variation 2789
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:144910819"
exon 2810..3049
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
variation 2839
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368824448"
variation 2866
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:56261501"
variation 2871
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201560518"
variation 2872
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="g"
/db_xref="dbSNP:201394687"
variation 2877
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372787552"
variation 2908
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:146051327"
variation 2925
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:55893926"
variation 2969
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:140189176"
variation 2977
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:375043027"
variation 2993
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="g"
/db_xref="dbSNP:143012134"
variation 3016
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:138592715"
exon 3050..3262
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
variation 3065
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:138875458"
variation 3071
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="c"
/db_xref="dbSNP:76632524"
variation 3108
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:139745553"
variation 3109
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201513301"
variation 3144
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:376158892"
variation 3145
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200151456"
variation 3154
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="g"
/replace="t"
/db_xref="dbSNP:149931822"
variation 3159
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201912253"
variation 3160
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:144979061"
variation 3161
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="c"
/db_xref="dbSNP:148701629"
variation 3169
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="c"
/db_xref="dbSNP:143481783"
variation 3208
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="g"
/db_xref="dbSNP:146674095"
variation 3261..3262
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace=""
/replace="g"
/db_xref="dbSNP:373533366"
exon 3263..3445
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
variation 3281
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="c"
/db_xref="dbSNP:200093063"
variation 3287
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376029356"
variation 3305
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:376168411"
variation 3332
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:371213377"
variation 3397
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:78594589"
variation 3404
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="g"
/db_xref="dbSNP:371119983"
variation 3416
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:77291164"
variation 3417
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:79510744"
variation 3426
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200530357"
variation 3443
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:140753098"
variation 3444
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201701292"
exon 3446..4660
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/inference="alignment:Splign:1.39.8"
variation 3448
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368134172"
variation 3483
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="g"
/db_xref="dbSNP:202164351"
variation 3484
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:150248315"
variation 3494
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:371701454"
variation 3495
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:138889090"
variation 3497
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375777895"
variation 3498
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368251549"
variation 3509
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:74017652"
variation 3527
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:141884131"
variation 3541
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:55768878"
variation 3552
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200252719"
variation 3577
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="g"
/db_xref="dbSNP:138517482"
variation 3589
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:143856120"
variation 3592
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:146062706"
variation 3617
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:148327383"
variation 3682
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141463070"
variation 3704
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:374910861"
variation 3714
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="g"
/db_xref="dbSNP:369537567"
variation 3720
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:372787160"
variation 3726
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372578344"
variation 3755
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="t"
/db_xref="dbSNP:80174893"
variation 3797
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:202158028"
variation 3925
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:56387705"
variation 3981
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="g"
/db_xref="dbSNP:376449356"
variation 4032
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:79506721"
variation 4119
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:113627530"
variation 4154
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:9924686"
variation 4260
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace=""
/replace="c"
/db_xref="dbSNP:67741806"
variation 4265
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="g"
/replace="t"
/db_xref="dbSNP:182091009"
variation 4450
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:185285376"
variation 4451
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:139998484"
variation 4452
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370266708"
variation 4469
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="t"
/db_xref="dbSNP:112781202"
variation 4472
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:112892099"
variation 4483
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="c"
/replace="g"
/db_xref="dbSNP:4787490"
variation 4487
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="t"
/db_xref="dbSNP:190881085"
variation 4497..4498
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace=""
/replace="ttt"
/db_xref="dbSNP:71751589"
variation 4497
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace=""
/replace="tt"
/db_xref="dbSNP:71704364"
variation 4528
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373316363"
variation 4565..4566
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
/replace=""
/replace="g"
/db_xref="dbSNP:36047629"
polyA_signal 4635..4640
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
polyA_site 4660
/gene="TAOK2"
/gene_synonym="MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2"
ORIGIN
tctccatcttggaattgggaggaagagggagagggagaccgggacgagaccggggctgtggtgcggagagaggctgagacggagaagaggagaggcagagagggcgcggggaccgtcagcagcaccttagctacaatcgttcagctattctcggaagagagaagggagagggaggaggccggggcgggagtgggggctgtcaccctcggaccccggcgtgagaggggccgtgcggccggacgtcctcggggtgggcccccagtcggtggccgaagacctacagctcaggcccctgggtcccaaatttccaggctttgcccctcctcctttctcagatacccgggtaacagtcctcatagtccagatatccgggactcgggtcccaacctctctaaacctgggtctctgtttcatagaatttcaaatatcaggttcaggcccctgcgtgcaccagtatccggggttcattccccgggcgttcaaatatcggattcagtctccatcccgttcagatattcggggttcagaccccacaatcagaaatccggaattcggcagctgtcgccctcgacgagggggaggactggaccgcgaggtcagattaggttgtcaccccctcccctccaggggaggcttcccgggcccgcccctcaggaagggcgaaagccgaggaagaggtggcaaggggaaaggtctccttgcccctctccctgcttggcagagccgctggaggaccccaggcggaagcggaggcgctggggcaccatagtgacccctaccaggccaggccccactctcagggcccccaggggccaccatgccagctgggggccgggccgggagcctgaaggacccagatgtggctgagctcttcttcaaggatgacccagaaaagctcttctctgacctccgggaaattggccatggcagctttggagccgtatactttgcccgggatgtccggaatagtgaggtggtggccatcaagaagatgtcctacagtgggaagcagtccaatgagaaatggcaagacatcatcaaggaggtgcggttcttacagaagctccggcatcccaacaccattcagtaccggggctgttacctgagggagcacacggcttggctggtaatggagtattgcctgggctcagcttctgaccttctagaagtgcacaagaaaccccttcaggaggtagagatcgcagctgtgacccacggggcgcttcagggcctggcatatctgcactcccacaacatgatccatagggatgtgaaggctggaaacatcctgctgtcagagccagggttagtgaagctaggggactttggttctgcgtccatcatggcacctgccaactccttcgtgggcaccccatactggatggcacccgaggtgatcctggccatggatgaggggcagtacgatggcaaagtggacgtctggtccttggggataacctgcatcgagctggctgaacggaaaccaccgctctttaacatgaatgcgatgagtgccttataccacattgcacagaacgaatcccccgtgctccagtcaggacactggtctgagtacttccggaattttgtcgactcctgtcttcagaaaatccctcaagacagaccaacctcagaggttctcctgaagcaccgctttgtgctccgggagcggccacccacagtcatcatggacctgatccagaggaccaaggatgccgtgcgggagctggacaacctgcagtaccgcaagatgaagaagatcctgttccaagaggcacccaacggccctggtgccgaggccccagaggaggaagaggaggccgagccctacatgcaccgggccgggactctgaccagcctcgagagtagccactcagtgcccagcatgtccatcagcgcctccagccagagcagctccgtcaacagcctagcagatgcctcagacaacgaggaagaggaggaggaggaggaggaagaggaggaggaggaagaaggccctgaagcccgggagatggccatgatgcaggagggggagcacacagtcacctctcacagctccattatccaccggctgccgggctctgacaacctatatgatgacccctaccagccagagataacccccagccctctccagccgcctgcagccccagctcccacttccaccacctcttccgcccgccgccgggcctactgccgtaaccgagaccactttgccaccatccgaaccgcctccctggtcagccgtcagatccaggagcatgagcaggactctgcgctgcgggagcagctgagcggctataagcggatgcgacgacagcaccagaagcagctgctggccctggagtcacggctgaggggtgaacgggaggagcacagtgcacggctgcagcgggagcttgaggcgcagcgggctggctttggggcagaggcagaaaagctggcccggcggcaccaggccataggtgagaaggaggcacgagctgcccaggccgaggagcggaagttccagcagcacatccttgggcagcagaagaaggagctggctgccctgctggaggcacagaagcggacctacaaacttcgcaaggaacagctgaaggaggagctccaggagaaccccagcactcccaagcgggagaaggccgagtggctgctgcggcagaaggagcagctccagcagtgccaggcggaggaggaagcagggctgctgcggcggcagcgccagtactttgagctgcagtgtcgccagtacaagcgcaagatgttgctggctcggcacagcctggaccaggacctgctgcgggaggacctgaacaagaagcagacccagaaggacttggagtgtgcactgctgcttcggcagcacgaggccacgcgggagctggagctgcggcagctccaggccgtgcagcgcacgcgggctgagctcacccgcctgcagcaccagacggagctgggcaaccagctggagtacaacaagcggcgtgagcaagagttgcggcagaagcatgcggcccaggttcgccagcagcccaagagcctcaaatctaaggagctgcagatcaagaagcagttccaggagacgtgtaagatccagactcggcagtacaaggctctgcgagcacacttgctggagaccacgcccaaagctcagcacaagagcctccttaagcggctcaaggaagagcagacccgcaagctggcgatcttggcggagcagtatgaccagtccatctcagagatgctcagctcacaggcgctgcggcttgatgagacccaggaggcagagttccaggcccttcggcagcagcttcaacaggagctggagctgctcaacgcttaccagagcaagatcaagatccgcacagagagccagcacgagagggagctgcgggagctggagcagagggtcgcgctgcggcgggcactgctggagcagcgggtggaagaggagctgctggccctgcagacaggacgctccgagcgaatccgcagtctgcttgagcggcaggcccgtgagatcgaggccttcgatgcggaaagcatgaggctgggcttctccagcatggctctggggggcatcccggctgaagctgctgcccagggctatcctgctccaccccctgccccagcctggccctcccgtcccgttccccgttctggggcacactggagccatggccctcctccaccaggcatgccccctccagcctggcgtcagccgtctctgctggctcccccaggccccccaaactggctggggccccccacacaaagtgggacaccccgtggcggagccctgctgctgctaagaaacagcccccagcccctgcggcgggcagcctcggggggcagtggcagtgagaatgtgggcccccctgctgccgcggtgcccgggcccctgagccgcagcaccagtgtcgcttcccacatcctcaatggttcttcccacttctattcctgaggtgcagcggggaggagcagatgagctgggcagggcaggggtgggtggagcctgaccctggagggcactgagctggaggcccctgcaagggtaggggacaagatgtaggctccagctcccctcagacctcctcatctcatgagcttcttggggctggccagtggcccagggccagcttggcgataggtgcctcaaggctgcctgggagccccgcctccctaccatggtgccaggggtctccctccgccacctaggaaaggagggagatgtgcgtgtcaaatattcatctagtcccctgggggaggggaagggtgggtctagacatactatattcagagaactatactaccctcacagtgaggccctcagacctgccacagggcagagcaggtctggggcctgaggcagggagaatgagaggccaccttactggcaggaaggatcaggatggggtcttggggtcaggatgcctgggtctcttcccgtaactgtctgacgtcctgtgccgtcttgtcctttatctttttttttttttttttaattgggatcagggctggggcggggaaacaagggaaggaccttggaaggggctgctcccaggcctggggggcagtcgtgggagcccctctcagctgtggggctggcacagagccccaggcaagcttttaataaactgttggttattctaacagaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:9344 -> Molecular function: GO:0004674 [protein serine/threonine kinase activity] evidence: IDA
GeneID:9344 -> Molecular function: GO:0005524 [ATP binding] evidence: IEA
GeneID:9344 -> Molecular function: GO:0031434 [mitogen-activated protein kinase kinase binding] evidence: IPI
GeneID:9344 -> Biological process: GO:0000186 [activation of MAPKK activity] evidence: IDA
GeneID:9344 -> Biological process: GO:0001558 [regulation of cell growth] evidence: NAS
GeneID:9344 -> Biological process: GO:0006612 [protein targeting to membrane] evidence: NAS
GeneID:9344 -> Biological process: GO:0006915 [apoptotic process] evidence: NAS
GeneID:9344 -> Biological process: GO:0006950 [response to stress] evidence: IDA
GeneID:9344 -> Biological process: GO:0006974 [response to DNA damage stimulus] evidence: IDA
GeneID:9344 -> Biological process: GO:0008360 [regulation of cell shape] evidence: IDA
GeneID:9344 -> Biological process: GO:0016477 [cell migration] evidence: NAS
GeneID:9344 -> Biological process: GO:0030036 [actin cytoskeleton organization] evidence: IDA
GeneID:9344 -> Biological process: GO:0031572 [G2 DNA damage checkpoint] evidence: IMP
GeneID:9344 -> Biological process: GO:0032874 [positive regulation of stress-activated MAPK cascade] evidence: IMP
GeneID:9344 -> Biological process: GO:0046330 [positive regulation of JNK cascade] evidence: IDA
GeneID:9344 -> Biological process: GO:0048041 [focal adhesion assembly] evidence: IDA
GeneID:9344 -> Biological process: GO:0051403 [stress-activated MAPK cascade] evidence: IDA
GeneID:9344 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:9344 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
GeneID:9344 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:9344 -> Cellular component: GO:0005856 [cytoskeleton] evidence: IEA
GeneID:9344 -> Cellular component: GO:0016021 [integral to membrane] evidence: IEA
GeneID:9344 -> Cellular component: GO:0016023 [cytoplasmic membrane-bounded vesicle] evidence: IDA
GeneID:9344 -> Cellular component: GO:0030425 [dendrite] evidence: IEA
GeneID:9344 -> Cellular component: GO:0030659 [cytoplasmic vesicle membrane] evidence: IEA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_004774 -> EC 2.7.11.1
by
@meso_cacase at
DBCLS
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