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2024-04-19 03:23:08, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_004760 3949 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens serine/threonine kinase 17a (STK17A), mRNA.
ACCESSION NM_004760
VERSION NM_004760.2 GI:109255244
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3949)
AUTHORS Mao,P., Hever,M.P., Niemaszyk,L.M., Haghkerdar,J.M., Yanco,E.G.,
Desai,D., Beyrouthy,M.J., Kerley-Hamilton,J.S., Freemantle,S.J. and
Spinella,M.J.
TITLE Serine/threonine kinase 17A is a novel p53 target gene and
modulator of cisplatin toxicity and reactive oxygen species in
testicular cancer cells
JOURNAL J. Biol. Chem. 286 (22), 19381-19391 (2011)
PUBMED 21489989
REMARK GeneRIF: identified STK17A as a novel direct target of p53 and a
modulator of cisplatin toxicity and reactive oxygen species in
testicular cancer cells.
REFERENCE 2 (bases 1 to 3949)
AUTHORS Shimada,M., Miyagawa,T., Kawashima,M., Tanaka,S., Honda,Y.,
Honda,M. and Tokunaga,K.
TITLE An approach based on a genome-wide association study reveals
candidate loci for narcolepsy
JOURNAL Hum. Genet. 128 (4), 433-441 (2010)
PUBMED 20677014
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 3 (bases 1 to 3949)
AUTHORS Landa,I., Ruiz-Llorente,S., Montero-Conde,C., Inglada-Perez,L.,
Schiavi,F., Leskela,S., Pita,G., Milne,R., Maravall,J., Ramos,I.,
Andia,V., Rodriguez-Poyo,P., Jara-Albarran,A., Meoro,A., del
Peso,C., Arribas,L., Iglesias,P., Caballero,J., Serrano,J.,
Pico,A., Pomares,F., Gimenez,G., Lopez-Mondejar,P., Castello,R.,
Merante-Boschin,I., Pelizzo,M.R., Mauricio,D., Opocher,G.,
Rodriguez-Antona,C., Gonzalez-Neira,A., Matias-Guiu,X.,
Santisteban,P. and Robledo,M.
TITLE The variant rs1867277 in FOXE1 gene confers thyroid cancer
susceptibility through the recruitment of USF1/USF2 transcription
factors
JOURNAL PLoS Genet. 5 (9), E1000637 (2009)
PUBMED 19730683
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 4 (bases 1 to 3949)
AUTHORS Sanjo,H., Kawai,T. and Akira,S.
TITLE DRAKs, novel serine/threonine kinases related to death-associated
protein kinase that trigger apoptosis
JOURNAL J. Biol. Chem. 273 (44), 29066-29071 (1998)
PUBMED 9786912
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BI461892.1, AB011420.1,
AC005189.2 and AW183478.1.
On Jun 19, 2006 this sequence version replaced gi:4758191.
Summary: This gene is a member of the DAP kinase-related
apoptosis-inducing protein kinase family and encodes an
autophosphorylated nuclear protein with a protein kinase domain.
The protein has apoptosis-inducing activity. [provided by RefSeq,
Jul 2008].
##Evidence-Data-START##
Transcript exon combination :: AB011420.1, BC047696.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025082 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-34 BI461892.1 34-67
35-1234 AB011420.1 1-1200
1235-3894 AC005189.2 170236-172895 c
3895-3949 AW183478.1 1-55 c
FEATURES Location/Qualifiers
source 1..3949
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="7"
/map="7p13"
gene 1..3949
/gene="STK17A"
/gene_synonym="DRAK1"
/note="serine/threonine kinase 17a"
/db_xref="GeneID:9263"
/db_xref="HGNC:11395"
/db_xref="MIM:604726"
exon 1..357
/gene="STK17A"
/gene_synonym="DRAK1"
/inference="alignment:Splign:1.39.8"
variation 1
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:147234162"
variation 110
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:368227991"
variation 115
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:10251937"
variation 116
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="g"
/db_xref="dbSNP:375416111"
variation 150
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="g"
/db_xref="dbSNP:141557830"
CDS 152..1396
/gene="STK17A"
/gene_synonym="DRAK1"
/EC_number="2.7.11.1"
/note="death-associated protein kinase-related 1;
serine/threonine kinase 17a (apoptosis-inducing); DAP
kinase-related apoptosis-inducing protein kinase 1"
/codon_start=1
/product="serine/threonine-protein kinase 17A"
/protein_id="NP_004751.2"
/db_xref="GI:109255245"
/db_xref="CCDS:CCDS5470.1"
/db_xref="GeneID:9263"
/db_xref="HGNC:11395"
/db_xref="MIM:604726"
/translation="
MIPLEKPGSGGSSPGATSGSGRAGRGLSGPCRPPPPPQARGLLTEIRAVVRTEPFQDGYSLCPGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVINLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSETKESIVTEELIVVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQEIPGEFIY
"
misc_feature 176..178
/gene="STK17A"
/gene_synonym="DRAK1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UEE5.2); phosphorylation site"
misc_feature 341..1114
/gene="STK17A"
/gene_synonym="DRAK1"
/note="Serine/Threonine protein kinases, catalytic domain;
Region: S_TKc; smart00220"
/db_xref="CDD:197582"
misc_feature 350..1111
/gene="STK17A"
/gene_synonym="DRAK1"
/note="Protein Kinases, catalytic domain; Region:
PKc_like; cl09925"
/db_xref="CDD:213116"
misc_feature order(350..364,374..376,413..415,419..421,515..517,
563..574,584..586,590..592,707..709,713..715,719..724,
728..730,770..772,779..781,824..835)
/gene="STK17A"
/gene_synonym="DRAK1"
/note="active site"
/db_xref="CDD:173623"
misc_feature order(350..364,374..376,413..415,419..421,515..517,
563..574,584..586,707..709,713..715,719..724,728..730,
770..772)
/gene="STK17A"
/gene_synonym="DRAK1"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:173623"
misc_feature order(362..364,584..586,590..592,707..709,713..715,
719..721,779..781,824..835)
/gene="STK17A"
/gene_synonym="DRAK1"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:173623"
misc_feature order(767..787,824..835)
/gene="STK17A"
/gene_synonym="DRAK1"
/note="activation loop (A-loop); other site"
/db_xref="CDD:173623"
variation 236
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="g"
/db_xref="dbSNP:200156727"
variation 278
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:11555027"
exon 358..570
/gene="STK17A"
/gene_synonym="DRAK1"
/inference="alignment:Splign:1.39.8"
variation 358
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:150394299"
variation 364
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:200924012"
variation 431
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:200968580"
variation 441
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:138232263"
variation 443
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="g"
/replace="t"
/db_xref="dbSNP:149595482"
variation 451
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200395183"
variation 453
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:143280410"
variation 527
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148044065"
variation 529
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="c"
/db_xref="dbSNP:56286238"
variation 568
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369399780"
variation 570
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="c"
/db_xref="dbSNP:374257441"
exon 571..715
/gene="STK17A"
/gene_synonym="DRAK1"
/inference="alignment:Splign:1.39.8"
variation 575
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:145372994"
variation 595
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:11555026"
variation 609
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:61732519"
variation 641
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:146830422"
variation 651
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:35940029"
variation 654
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:77026432"
variation 659
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:371239772"
variation 692
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:374240387"
exon 716..842
/gene="STK17A"
/gene_synonym="DRAK1"
/inference="alignment:Splign:1.39.8"
variation 742
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:111947320"
variation 762
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="t"
/db_xref="dbSNP:139022225"
variation 812
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:149915695"
variation 813
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:144946086"
variation 839
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="g"
/replace="t"
/db_xref="dbSNP:201447491"
exon 843..891
/gene="STK17A"
/gene_synonym="DRAK1"
/inference="alignment:Splign:1.39.8"
variation 856
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:2230753"
variation 875
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:114472894"
variation 888
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:144785063"
exon 892..1071
/gene="STK17A"
/gene_synonym="DRAK1"
/inference="alignment:Splign:1.39.8"
variation 946
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="c"
/db_xref="dbSNP:201962865"
variation 985
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="g"
/replace="t"
/db_xref="dbSNP:376734546"
variation 989
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="t"
/db_xref="dbSNP:139281234"
variation 1007
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="g"
/db_xref="dbSNP:3779062"
variation 1030
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369370775"
variation 1047
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:374135927"
exon 1072..3933
/gene="STK17A"
/gene_synonym="DRAK1"
/inference="alignment:Splign:1.39.8"
variation 1084
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="t"
/db_xref="dbSNP:201695280"
variation 1120
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="g"
/db_xref="dbSNP:371459681"
variation 1141
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:377533782"
variation 1153
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:10233697"
variation 1165
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:200980304"
variation 1167
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="c"
/db_xref="dbSNP:199987361"
variation 1223
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="c"
/db_xref="dbSNP:143807634"
variation 1235
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:1044141"
variation 1245
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:76244589"
variation 1252
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:140929501"
variation 1253
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:202162765"
variation 1285
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:368867119"
variation 1288
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:1801821"
variation 1317
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201305620"
variation 1322
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:371595934"
variation 1323
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="c"
/db_xref="dbSNP:150230872"
variation 1340
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:193218605"
variation 1362
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="g"
/replace="t"
/db_xref="dbSNP:138840285"
variation 1368
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:375843224"
variation 1392
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:142571975"
variation 1395
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:144740791"
variation 1413
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="g"
/replace="t"
/db_xref="dbSNP:183178602"
variation 1432
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:15866"
variation 1438
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:142415211"
variation 1471
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="g"
/db_xref="dbSNP:371781465"
STS 1479..1643
/gene="STK17A"
/gene_synonym="DRAK1"
/standard_name="STS-R46116"
/db_xref="UniSTS:22341"
variation 1503
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="t"
/db_xref="dbSNP:138391954"
STS 1536..1677
/gene="STK17A"
/gene_synonym="DRAK1"
/standard_name="D7S2881"
/db_xref="UniSTS:2247"
STS 1536..1655
/gene="STK17A"
/gene_synonym="DRAK1"
/standard_name="RH98239"
/db_xref="UniSTS:89444"
variation 1554
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:187859672"
variation 1580
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="g"
/replace="t"
/db_xref="dbSNP:699509"
variation 1658
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="t"
/db_xref="dbSNP:191259928"
polyA_site 1739
/gene="STK17A"
/gene_synonym="DRAK1"
variation 1740
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:1044217"
variation 1937..1938
/gene="STK17A"
/gene_synonym="DRAK1"
/replace=""
/replace="ta"
/db_xref="dbSNP:376645116"
variation 2039
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="g"
/db_xref="dbSNP:142932567"
variation 2042
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:183754368"
variation 2091
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:7778665"
variation 2182
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:374172032"
variation 2240
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="t"
/db_xref="dbSNP:150675734"
variation 2307..2308
/gene="STK17A"
/gene_synonym="DRAK1"
/replace=""
/replace="agagagagagagag"
/db_xref="dbSNP:71563913"
variation 2308..2309
/gene="STK17A"
/gene_synonym="DRAK1"
/replace=""
/replace="ct"
/replace="ctctctctct"
/replace="ctctctctctctctct"
/db_xref="dbSNP:3832501"
variation 2309..2310
/gene="STK17A"
/gene_synonym="DRAK1"
/replace=""
/replace="ga"
/replace="gaga"
/db_xref="dbSNP:71885285"
variation 2331..2332
/gene="STK17A"
/gene_synonym="DRAK1"
/replace=""
/replace="gt"
/db_xref="dbSNP:138488469"
variation 2332..2333
/gene="STK17A"
/gene_synonym="DRAK1"
/replace=""
/replace="agagagagagagagag"
/db_xref="dbSNP:72102068"
variation 2455
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:1044220"
variation 2583..2584
/gene="STK17A"
/gene_synonym="DRAK1"
/replace=""
/replace="a"
/db_xref="dbSNP:35427606"
variation 2612
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:139973881"
variation 2652
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:189679831"
variation 2675
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370929471"
variation 2763
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:2108411"
variation 2843
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:149863507"
STS 3060..3266
/gene="STK17A"
/gene_synonym="DRAK1"
/standard_name="STS-T95619"
/db_xref="UniSTS:69912"
STS 3191..3301
/gene="STK17A"
/gene_synonym="DRAK1"
/standard_name="SHGC-33787"
/db_xref="UniSTS:59994"
variation 3218..3220
/gene="STK17A"
/gene_synonym="DRAK1"
/replace=""
/replace="aaa"
/db_xref="dbSNP:146270922"
variation 3243
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="t"
/db_xref="dbSNP:7784009"
variation 3254
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="g"
/db_xref="dbSNP:113820102"
polyA_signal 3321..3326
/gene="STK17A"
/gene_synonym="DRAK1"
polyA_site 3340
/gene="STK17A"
/gene_synonym="DRAK1"
variation 3398
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="g"
/db_xref="dbSNP:192754509"
variation 3437
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369871051"
variation 3659
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:373406303"
variation 3738
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="a"
/replace="g"
/db_xref="dbSNP:185154969"
variation 3784..3786
/gene="STK17A"
/gene_synonym="DRAK1"
/replace=""
/replace="ttg"
/db_xref="dbSNP:141793546"
variation 3808
/gene="STK17A"
/gene_synonym="DRAK1"
/replace="c"
/replace="g"
/db_xref="dbSNP:115172462"
polyA_signal 3913..3918
/gene="STK17A"
/gene_synonym="DRAK1"
polyA_site 3933
/gene="STK17A"
/gene_synonym="DRAK1"
ORIGIN
ggtagtctgcctgccgcagtccgagcgccgcgctggggagagcgggtgtttgaaggctccgcggaccggcactaggagccgggggcgggtccgtgaccctccggctgctcggagtgaacaggcggccaggaaagaagcgggcctgaacaccatgatccctttggagaagccaggcagcggcggctcctccccaggcgccacctcaggctcgggccgggcaggccggggtctgagcgggccgtgccggccgccgccgccgccccaggcccgcgggctgctgacagagatacgcgccgtggtgcgcaccgagcccttccaggacggctacagcctgtgcccgggccgggagctgggcagggggaaatttgcagtggtgagaaaatgtataaagaaagattctgggaaagaatttgctgcaaagttcatgagaaaaagaagaaaaggccaagattgtcggatggaaataattcatgagattgctgtacttgaactagcacaagacaatccttgggtcattaatttacatgaagtttatgagactgcatcagaaatgatcttagttctggaatatgctgctgggggtgaaatctttgaccagtgtgttgcagacagagaagaagcctttaaagaaaaagatgttcaaagacttatgcgacagattttagaaggtgttcactttttacacactcgtgatgtagttcatcttgatttgaagcctcagaatattctgttgacaagtgaatctccattgggtgacattaagattgttgattttggcctttcaagaatattgaagaacagtgaagagctccgagaaattatgggtacccctgaatatgtggctcctgaaattcttagttatgatcctataagcatggcaacagatatgtggagcattggagtgttaacatatgtcatgcttacaggaatatcacctttcttaggcaatgataaacaagaaacattcttaaacatctcacagatgaatttaagttattctgaggaagaatttgatgttttgtctgagtcggctgttgatttcatcaggacacttttagttaagaaacctgaagatcgagccactgctgaagaatgtctaaagcacccctggttgacacagagcagtattcaagagccttctttcaggatggaaaaggcactagaagaagcaaatgccctccaagaaggtcattctgtgcctgaaattaattcggataccgacaaatcagaaaccaaggaatccattgtaaccgaagagttaattgtagttacttcatatactctaggacaatgcagacagtctgaaaaagagaaaatggagcaaaaggccatttccaaacgatttaaatttgaggaacctttgctacaagaaattccaggagaatttatctactgagcaatatttccctttagaacttcaagatttctacattgaaaatgttaatattatttatggacctctggccaaatggtacatgtactggaagtggataaccagtatcacttacacaaacaaaaataactttgtcaaatttgtggagttaggtggaagccagattttaaaagttgccaaccaggagatttaacaggtacagttacccgtttcaatgttatttttaagaagggagatgttggcacctttgaattctacatcctgtttctccagaatgagaatttgtgtacaaagatatttgtattcactttctttaaaaaatccaagtaaaagtgccaaaactacacttctgtaaatctcttgcattattcatatgtgtatctatatctgcataatgtttgttaatgtctactaaaattgctactttttcactttggatttgtttttggcaaaattttagtctaaacagacatctaaattttcgagacttagaataacattcactaaagtttgataatgtcttttttaaatattttcttactgctttatagtgacttgatttggtttctgttgtgtttttgcctaaatactagtaacatatcagtgaaaaaccctaattttttttctcttcaatgtcactagtaagagaggtggtaatttttcacctctgaaattattctgggtttaggtgtcagctcttgagctgcttccctcatcacaccacactcacatgcatctgttctctctcacactctatacccctgccacttcctggcacctccccccatgcttgtcatttaattttggccacttgtaggtatcagtgtgatctgatcaacactctggttaccttggtcagtgaaaagatgctactatattgcttttgtcccaaagtgagtaaaatcccctagagcagagagagagagagagagagagagtgtcttcatgccaaccacagcctgtttctgctgagtttcttatcagccctcaagctatgctaggaaaagttataaaatgccaaaatatttataaacatttactttgtccataaaaaatttacattggatactctgtaagtaggaggtactttgtcccaaaaagatgtataagaatgtactaatagttttatttgattaggattgaacagttcagttgtatctatgccccacagtgaccagtaaagtccaattaaaatatggaaatgtaaaagtgtatgccgaataccttaaagtaactaattatccttacacacaaaaggctcagtgcattaaatatttgcctatcacctgtgtgctgtgtaccgtggccatgcctcgctctgcactatgaacaactcagacctgtcccttcacggtctgattagggtgtcacacaaagctctctccctaacatggtttctcaactgtcaaaatcatgaaaatgacagcacctaaccactattttaaagtatgtacagtaaatacccaaatgtgtgtaaatgtcatagacatatacaaagtcagtaatctcacccagtcctgctgtgtgaacctgtcaaagcacctgggagtgccctttacaccattaggtgaaattcatcaggcacttcagacaaccaggttgcactgttttctcactaaattggctttatttatacagtttcctggaacctagcattcctaaacaagctccaaaatgcagaagaagaaattgtgccacagtgatagagtttttaatgaatatccatggccacagttttgagtctcaggtaagtcttggaagaagttaaacacagtattaggcaaatatttatctctctgaaaaaatagggaggaggtgaccaggaaaaaataaccactattgaatgacacgtttgtacttgatggatctgtcatcaagttttaaaatcagaatcatttgggctttttaaaaaccattttatactcgtaataaatatatttaatataattgctgtatttgtgagaaagatctgttttcttttagctggccacttcagtttgctgcgtatctttagctgctgttgtgcttaaatactgagtcatagggtgcttttttaagaggcccttcagaatatacttgtaaaggtgtattggcattttttggtttataagataaaaacagggcatgaagagccttcatagtattaggccaaataaaatctattaataactgccagctagctctacacttatctaaagctgttaatgttcctttttttctatcaccaaatttataaaggactaaacagtactattgagtttactcggtttataaatccagttttaactataattcaacaatattttggtgtggtgaaacgttgtttatgaaatgtataaaatgtataagttttaatcaactgggaaatgatatttgattgatcttgtgttttgttgttttcaaatgaaaactaggaggtaattaatacctttctctagtagtggtatagaggaaggacagatgctcattgttgaatctcttaaatttttccagctaacctcagtttggaagaaaaatgtattaaagggttataaagatcaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:9263 -> Molecular function: GO:0004674 [protein serine/threonine kinase activity] evidence: IDA
GeneID:9263 -> Molecular function: GO:0005524 [ATP binding] evidence: IDA
GeneID:9263 -> Biological process: GO:0006468 [protein phosphorylation] evidence: IDA
GeneID:9263 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:9263 -> Biological process: GO:0006917 [induction of apoptosis] evidence: IMP
GeneID:9263 -> Biological process: GO:0007243 [intracellular protein kinase cascade] evidence: IDA
GeneID:9263 -> Biological process: GO:0043065 [positive regulation of apoptotic process] evidence: IMP
GeneID:9263 -> Biological process: GO:2000377 [regulation of reactive oxygen species metabolic process] evidence: IMP
GeneID:9263 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_004751 -> EC 2.7.11.1
by
@meso_cacase at
DBCLS
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