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2019-03-25 08:59:16, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_004555               6453 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens nuclear factor of activated T-cells, cytoplasmic,
            calcineurin-dependent 3 (NFATC3), transcript variant 2, mRNA.
ACCESSION   NM_004555
VERSION     NM_004555.3  GI:312283724
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6453)
  AUTHORS   Yissachar,N., Sharar Fischler,T., Cohen,A.A., Reich-Zeliger,S.,
            Russ,D., Shifrut,E., Porat,Z. and Friedman,N.
  TITLE     Dynamic response diversity of NFAT isoforms in individual living
            cells
  JOURNAL   Mol. Cell 49 (2), 322-330 (2013)
   PUBMED   23219532
  REMARK    GeneRIF: The closely related transcription factors NFAT1 and NFAT4
            possess distinct nuclear localization dynamics in response to cell
            stimulation.
REFERENCE   2  (bases 1 to 6453)
  AUTHORS   Ulrich,J.D., Kim,M.S., Houlihan,P.R., Shutov,L.P., Mohapatra,D.P.,
            Strack,S. and Usachev,Y.M.
  TITLE     Distinct activation properties of the nuclear factor of activated
            T-cells (NFAT) isoforms NFATc3 and NFATc4 in neurons
  JOURNAL   J. Biol. Chem. 287 (45), 37594-37609 (2012)
   PUBMED   22977251
  REMARK    GeneRIF: Data indicate that NFATc3 undergoes rapid
            dephosphorylation and nuclear translocation that are essentially
            complete within 20 min, although NFATc4 remains phosphorylated and
            localized to the cytosol.
REFERENCE   3  (bases 1 to 6453)
  AUTHORS   Wollebo,H.S., Melis,S., Khalili,K., Safak,M. and White,M.K.
  TITLE     Cooperative roles of NF-kappaB and NFAT4 in polyomavirus JC
            regulation at the KB control element
  JOURNAL   Virology 432 (1), 146-154 (2012)
   PUBMED   22749879
  REMARK    GeneRIF: The authors report that NFAT4 and NF-kappaB interact at
            the KB element to co-operatively activate both human polyomavirus
            JC early and late transcription and viral DNA replication.
REFERENCE   4  (bases 1 to 6453)
  AUTHORS   Jin,S.M., Cho,H.J., Kim,Y.W., Hwang,J.Y. and Mook-Jung,I.
  TITLE     Abeta-induced Ca(2+) influx regulates astrocytic BACE1 expression
            via calcineurin/NFAT4 signals
  JOURNAL   Biochem. Biophys. Res. Commun. 425 (3), 649-655 (2012)
   PUBMED   22846573
  REMARK    GeneRIF: Abeta-activated NFAT4 proteins were associated with
            astrocytic BACE1 gene expression via direct interaction with the
            BACE1 promoter region.
REFERENCE   5  (bases 1 to 6453)
  AUTHORS   Urso,K., Alfranca,A., Martinez-Martinez,S., Escolano,A., Ortega,I.,
            Rodriguez,A. and Redondo,J.M.
  TITLE     NFATc3 regulates the transcription of genes involved in T-cell
            activation and angiogenesis
  JOURNAL   Blood 118 (3), 795-803 (2011)
   PUBMED   21642596
  REMARK    GeneRIF: NFATc3 is specifically required for IL2 and
            cyclooxygenase-2 (COX2) gene expression in T cells and for T-cell
            proliferation and NFATc3 regulates COX2 in endothelial cells
REFERENCE   6  (bases 1 to 6453)
  AUTHORS   Masuda,E.S., Liu,J., Imamura,R., Imai,S.I., Arai,K.I. and Arai,N.
  TITLE     Control of NFATx1 nuclear translocation by a calcineurin-regulated
            inhibitory domain
  JOURNAL   Mol. Cell. Biol. 17 (4), 2066-2075 (1997)
   PUBMED   9121455
REFERENCE   7  (bases 1 to 6453)
  AUTHORS   Rao,A., Luo,C. and Hogan,P.G.
  TITLE     Transcription factors of the NFAT family: regulation and function
  JOURNAL   Annu. Rev. Immunol. 15, 707-747 (1997)
   PUBMED   9143705
  REMARK    Review article
REFERENCE   8  (bases 1 to 6453)
  AUTHORS   Hoey,T., Sun,Y.L., Williamson,K. and Xu,X.
  TITLE     Isolation of two new members of the NF-AT gene family and
            functional characterization of the NF-AT proteins
  JOURNAL   Immunity 2 (5), 461-472 (1995)
   PUBMED   7749981
REFERENCE   9  (bases 1 to 6453)
  AUTHORS   Masuda,E.S., Naito,Y., Tokumitsu,H., Campbell,D., Saito,F.,
            Hannum,C., Arai,K. and Arai,N.
  TITLE     NFATx, a novel member of the nuclear factor of activated T cells
            family that is expressed predominantly in the thymus
  JOURNAL   Mol. Cell. Biol. 15 (5), 2697-2706 (1995)
   PUBMED   7739550
REFERENCE   10 (bases 1 to 6453)
  AUTHORS   Vacca,A., Farina,M., Maroder,M., Alesse,E., Screpanti,I., Frati,L.
            and Gulino,A.
  TITLE     Human immunodeficiency virus type-1 tat enhances interleukin-2
            promoter activity through synergism with phorbol ester and
            calcium-mediated activation of the NF-AT cis-regulatory motif
  JOURNAL   Biochem. Biophys. Res. Commun. 205 (1), 467-474 (1994)
   PUBMED   7999066
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BU849493.1, L41067.1,
            AC020978.10 and CA418693.1.
            On Nov 20, 2010 this sequence version replaced gi:27886542.
            
            Summary: The product of this gene is a member of the nuclear
            factors of activated T cells DNA-binding transcription complex.
            This complex consists of at least two components: a preexisting
            cytosolic component that translocates to the nucleus upon T cell
            receptor (TCR) stimulation and an inducible nuclear component.
            Other members of this family participate to form this complex also.
            The product of this gene plays a role in the regulation of gene
            expression in T cells and immature thymocytes. Several transcript
            variants encoding distinct isoforms have been identified for this
            gene. [provided by RefSeq, Nov 2010].
            
            Transcript Variant: This variant (2) contains an additional segment
            in the coding region, which causes a frameshift, compared to
            variant 1. The resulting isoform (2) contains a shorter and
            distinct C-terminus compared to isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: L41067.1, EU887605.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025084, ERS025088 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-106               BU849493.1         1-106
            107-4074            L41067.1           1-3968
            4075-6418           AC020978.10        111815-114158       c
            6419-6453           CA418693.1         1-35                c
FEATURES             Location/Qualifiers
     source          1..6453
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16q22.2"
     gene            1..6453
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /note="nuclear factor of activated T-cells, cytoplasmic,
                     calcineurin-dependent 3"
                     /db_xref="GeneID:4775"
                     /db_xref="HGNC:7777"
                     /db_xref="HPRD:04077"
                     /db_xref="MIM:602698"
     exon            1..419
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    284..286
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /note="upstream in-frame stop codon"
     CDS             317..3523
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /note="isoform 2 is encoded by transcript variant 2; T
                     cell transcription factor NFAT4; nuclear factor of
                     activated T-cells c3 isoform IE-Xa; NF-ATc3"
                     /codon_start=1
                     /product="nuclear factor of activated T-cells, cytoplasmic
                     3 isoform 2"
                     /protein_id="NP_004546.1"
                     /db_xref="GI:4758804"
                     /db_xref="CCDS:CCDS10862.1"
                     /db_xref="GeneID:4775"
                     /db_xref="HGNC:7777"
                     /db_xref="HPRD:04077"
                     /db_xref="MIM:602698"
                     /translation="
MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDREPNFATIGLQDITLDDDQFISDLEHQPSGSAEKWPNHSVLSCPAPFWRI
"
     misc_feature    320..322
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N-acetylthreonine; propagated from
                     UniProtKB/Swiss-Prot (Q12968.1); acetylation site"
     misc_feature    641..658
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q12968.1);
                     Region: Calcineurin-binding"
     misc_feature    803..805
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /db_xref="HPRD:04206"
     misc_feature    809..811
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /db_xref="HPRD:04206"
     misc_feature    926..928
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /db_xref="HPRD:02739"
     misc_feature    935..1240
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q12968.1);
                     Region: 3 X SP repeats"
     misc_feature    935..937
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /db_xref="HPRD:02739"
     misc_feature    944..946
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /db_xref="HPRD:02739"
     misc_feature    947..949
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /db_xref="HPRD:02739"
     misc_feature    959..961
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /db_xref="HPRD:02739"
     misc_feature    1133..1141
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q12968.1);
                     Region: Nuclear localization signal"
     misc_feature    1577..2098
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /note="N-terminal sub-domain of the Rel homology domain
                     (RHD) of nuclear factor of activated T-cells (NFAT)
                     proteins; Region: RHD-n_NFAT; cd07881"
                     /db_xref="CDD:143641"
     misc_feature    order(1646..1648,1655..1657,1661..1666,1670..1678,
                     1817..1819,1940..1942,1946..1951,1991..1996,2000..2002,
                     2093..2095)
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143641"
     misc_feature    2111..2413
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /note="IPT domain of the NFAT family of transcription
                     factors. NFAT transcription complexes are a target of
                     calcineurin, a calcium dependent phosphatase, and activate
                     genes mainly involved in cell-cell-interaction; Region:
                     IPT_NFAT; cd01178"
                     /db_xref="CDD:28993"
     misc_feature    order(2183..2185,2375..2377)
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /note="DNA binding sites [nucleotide binding]"
                     /db_xref="CDD:28993"
     misc_feature    2372..2380
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q12968.1);
                     Region: Nuclear localization signal"
     exon            420..1554
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /inference="alignment:Splign:1.39.8"
     exon            1555..1717
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /inference="alignment:Splign:1.39.8"
     exon            1718..1917
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /inference="alignment:Splign:1.39.8"
     exon            1918..2090
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /inference="alignment:Splign:1.39.8"
     exon            2091..2231
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /inference="alignment:Splign:1.39.8"
     exon            2232..2287
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /inference="alignment:Splign:1.39.8"
     exon            2288..2414
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /inference="alignment:Splign:1.39.8"
     exon            2415..3422
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /inference="alignment:Splign:1.39.8"
     exon            3423..3526
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /inference="alignment:Splign:1.39.8"
     exon            3527..6436
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /inference="alignment:Splign:1.39.8"
     STS             3558..3775
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /standard_name="SHGC-35392"
                     /db_xref="UniSTS:46447"
     STS             3636..3796
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /standard_name="RH17654"
                     /db_xref="UniSTS:70905"
     STS             3820..3944
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /standard_name="RH78919"
                     /db_xref="UniSTS:7965"
     STS             3926..4025
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /standard_name="SHGC-60786"
                     /db_xref="UniSTS:3222"
     STS             4720..4966
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /standard_name="RH79943"
                     /db_xref="UniSTS:83977"
     STS             4772..4915
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /standard_name="RH64885"
                     /db_xref="UniSTS:87887"
     STS             6184..6317
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /standard_name="A002B46"
                     /db_xref="UniSTS:61142"
     STS             6184..6317
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /standard_name="G19908"
                     /db_xref="UniSTS:61141"
     STS             6207..6383
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /standard_name="RH16192"
                     /db_xref="UniSTS:10495"
     variation       complement(6232)
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11043"
     STS             6291..6428
                     /gene="NFATC3"
                     /gene_synonym="NFAT4; NFATX"
                     /standard_name="SGC32906"
                     /db_xref="UniSTS:9489"
ORIGIN      
cggcagggcgcgagagcgcacccgcggcggcggtggcggcgactgtgggggggcggcggggaacattggctaagccgacagtggaggcttaggcaccggtggcgggcggctgcggttcctggtgctgctcggcgcgcggccagctttcggaacggaacgctcggcgtcgcgggccccgcccggaaagtttgccgtggagtcgcgacctcttggcccgcgcggcccggcatgaagcggcgttgaggagctgctgccgccgcttgccgctgccgccgccgccgcctgaggaggagctgcagcaccctgggccacgccgatgactactgcaaactgtggcgcccacgacgagctcgacttcaaactcgtctttggcgaggacggggcgccggcgccgccgcccccgggctcgcggcctgcagatcttgagccagatgattgtgcatccatttacatctttaatgtagatccacctccatctactttaaccacaccactttgcttaccacatcatggattaccgtctcactcttctgttttgtcaccatcgtttcagctccaaagtcacaaaaactatgaaggaacttgtgagattcctgaatctaaatatagcccattaggtggtcccaaaccctttgagtgcccaagtattcaaattacatctatctctcctaactgtcatcaagaattagatgcacatgaagatgacctacagataaatgacccagaacgggaatttttggaaaggccttctagagatcatctctatcttcctcttgagccatcctaccgggagtcttctcttagtcctagtcctgccagcagcatctcttctaggagttggttctctgatgcatcttcttgtgaatcgctttcacatatttatgatgatgtggactcagagttgaatgaagctgcagcccgatttacccttggatcccctctgacttctcctggtggctctccagggggctgccctggagaagaaacttggcatcaacagtatggacttggacactcattatcacccaggcaatctccttgccactctcctagatccagtgtcactgatgagaattggctgagccccaggccagcctcaggaccctcatcaaggcccacatccccctgtgggaaacggaggcactccagtgctgaagtttgttatgctgggtccctttcaccccatcactcacctgttccttcacctggtcactcccccaggggaagtgtgacagaagatacgtggctcaatgcttctgtccatggtgggtcaggccttggccctgcagtttttccatttcagtactgtgtagagactgacatccctctcaaaacaaggaaaacttctgaagatcaagctgccatactaccaggaaaattagagctgtgttcagatgaccaagggagtttatcaccagcccgggagacttcaatagatgatggccttggatctcagtatcctttaaagaaagattcatgtggtgatcagtttctttcagttccttcaccctttacctggagcaaaccaaagcctggccacacccctatatttcgcacatcttcattacctccactagactggcctttaccagctcattttggacaatgtgaactgaaaatagaagtgcaacctaaaactcatcatcgagcccattatgaaactgaaggtagccgaggggcagtaaaagcatctactgggggacatcctgttgtgaagctcctgggctataacgaaaagccaataaatctacaaatgtttattgggacagcagatgatcgatatttacgacctcatgcattttaccaggtgcatcgaatcactgggaagacagtcgctactgcaagccaagagataataattgccagtacaaaagttctggaaattccacttcttcctgaaaataatatgtcagccagtattgattgtgcaggtattttgaaactccgcaattcagatatagaacttcgaaaaggagaaactgatattggcagaaagaatactagagtacgacttgtgtttcgtgtacacatcccacagcccagtggaaaagtcctttctctgcagatagcctctatacccgttgagtgctcccagcggtctgctcaagaacttcctcatattgagaagtacagtatcaacagttgttctgtaaatggaggtcatgaaatggttgtgactggatctaattttcttccagaatccaaaatcatttttcttgaaaaaggacaagatggacgacctcagtgggaggtagaagggaagataatcagggaaaaatgtcaaggggctcacattgtccttgaagttcctccatatcataacccagcagttacagctgcagtgcaggtgcacttttatctttgcaatggcaagaggaaaaaaagccagtctcaacgttttacttatacaccagttttgatgaagcaagaacacagagaagagattgatttgtcttcagttccatctttgcctgtgcctcatcctgctcagacccagaggccttcctctgattcagggtgttcacatgacagtgtactgtcaggacagagaagtttgatttgctccatcccacaaacatatgcatccatggtgacctcatcccatctgccacagttgcagtgtagagatgagagtgttagtaaagaacagcatatgattccttctccaattgtacaccagccttttcaagtcacaccaacacctcctgtggggtcttcctatcagcctatgcaaactaatgttgtgtacaatggaccaacttgtcttcctattaatgctgcctctagtcaagaatttgattcagttttgtttcagcaggatgcaactctttctggtttagtgaatcttggctgtcaaccactgtcatccataccatttcattcttcaaattcaggctcaacaggacatctcttagcccatacacctcattctgtgcataccctgcctcatctgcaatcaatgggatatcattgttcaaatacaggacaaagatctctttcttctccagtggctgaccagattacaggtcagccttcgtctcagttacaacctattacatatggtccttcacattcagggtctgctacaacagcttccccagcagcttctcatcccttggctagttcaccgctttctgggccaccatctcctcagcttcagcctatgccttaccaatctcctagctcaggaactgcctcatcaccgtctccagccaccagaatgcattctggacagcactcaactcaagcacaaagtacgggccaggggggtctttctgcaccttcatccttaatatgtcacagtttgtgtgatccagcgtcatttccacctgatggggcaactgtgagcattaaacctgaaccagaagatcgagagcctaactttgcaaccattggtctgcaggacatcactttagatgatgaccaatttatatctgacttggaacaccagccatcaggttcagcagagaaatggcctaaccacagtgtgctctcatgtccagctcctttctggagaatctagaggtgaacgagataattgggagagacatgtcccagatttctgtttcccaaggagcaggggtgagcaggcaggctcccctcccgagtcctgagtccctggatttaggaagatctgatgggctctaacagtgcttactgcagccttgtgtccaccaccaacttctcagcatgtttctctccttggaccttgggtttccaactctgcagccttcaggtctggggccaggagtgggacccaccatttgtggggaaagtagcattcctccacctcaggccttgggtagatttggcaaaagaacaggagcagcataggctgtttgagctttggggaaatgaactttgctttttatatttaactaggatacttttatatgatgggtgctttgagtgtgaatgcagcaggctctcttgtttccgaggtgctgcttttgcaggtgacctggttacttagctaggattggtgatttgtactgctttatggtcatttgaagggccctttagtttttatgataatttttaaaataggaacttttgataagaccttctagaagcaaaaaaaaaaaaaaaaaaaaaaaaaagaaaaaaaaagaaaagaaaaaaagaaaaagaaaaaaatatcccaagcccacacctatgcctcagaaagtcagcatgtgtcctgaagacgttcatagatttataggaaataaagccaaatgtagctcatacctctttataaaactaaactgttgttagataaaatgagaagagaccattccatcattgaagtgttggaatataaaaagacattccagagcatagccttttggtaactttctaggtaatcttgcaatctctccatactggctccatgttgaaattgctttttccctcaggaccctgggtaagatggctacatttaaggtgactctgaatggtggggttctagcttggtcactttcatttcttgccatcataaaaactagtaggctgtggagtgcgcttcctgtttgtgtcatctggtcgtagaaccttttccaaacagaagcatctgcctttggctgttctgtgacctttgaagccagtctcagtggtttaggcagctttgcagttctaactctagctagaggccaggctgtgtgcagagctaaagcacaaatgagcagtacatcagcatgggcagagaaaatacaggactccagatgggaaggttttaagagtcacactggcatggaaggcttatctgccattctatttatagcctgaaatgattctggcctaccctgtcctgtctgtatgatctaaaaaccagccttttccccagaaggctctgagcacatccagaagtgataacctgaccctccacaccaaagacaccctggtgctgctgctggtgagactggtgtccaaggcagggcccagcagaaactgcagcctgctgtctaccaaaggaggtacccgagttgggtactttaaaaaaaaaaaaaacctgcccttacccctctccctaatgggattttttttacctgttcctgggcccattacagagcctctgaagtttgcagtatgctttcaaatgaaataatatacttccattgattcaggaagcagattttttgagtgcctatatgtgagacagtgtgctggttgaaggcctgatgctgttattccaggagactgcaggcccttgatgccaggactctctctactaaggccagttcaggtctgggaaagggagctggcctattgcccaccacctgttgtcagtaggttaggagctgttgactcaggatgaggaagtatggtctttaaaaaaaacaaaatatattttagatttctcccctaaagttagttagagaaaaaggtctattcttcagcagatcactgtggcccctcttggagctgggtgttttcaaattttcttgaaaagtgagttgtgtcacagaatgtggatagtgagatttgcttctgggcctgtggttggacgcccacagcttcctttggaggggcaagaagttggcctctcggttgacattccagagaaatggccagacttgcccctacccttttgcccctggtgtagctgcctcacatgaggttattgcaagagttccccttgcaataccctttgtgccctcaagaattaaaagcctctatgatccagagttgctatgcaccaaattttgatgccttctaaataccttgatgcctgtagcactagaaatgctttcctatttaaaataaacattaaattttaaaatagagctttgtatactatgtaagcagttttatatcagctttgtaaaagctttggtgttaagagtcaatattttttggctttgtagataaagacttaaatttttgtgcaacatagtggtgttaaagcacacatccattggactatgcaaatcaatttctactagcagcactgagcaactgggcacgtgctagtacgcaccccctcctactctaactgtgctagctcttgggttgaggaatggaatgggtagccttctgcttactggagatgcacagagaaacatggctgaaaacagctttaaaaagaacatgtctttgggttcatgtgtggtgctgctgcccgggtgtaaactatccccacccagggccagccattatcaccagacctcttctgggcctggctgtgaagccctgtttttggtattcagaatggatctttaaggctcagatgggctcaaattgaaaccttgtgttttataaaatggatgtttagtaaaggaactggttctcagttatgtttacagcacttggaattgtgtgttcttgtacattttgtattttaaaaccttttatgggagtgcagtgctccttacacaaatacaaagggaagaagagccagcagttgaggctcctcagttttagtgctgaaataataaacagtgacaggtcaacagtaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:4775 -> Molecular function: GO:0003677 [DNA binding] evidence: IEA
            GeneID:4775 -> Molecular function: GO:0003682 [chromatin binding] evidence: IEA
            GeneID:4775 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IEA
            GeneID:4775 -> Biological process: GO:0001569 [patterning of blood vessels] evidence: IEA
            GeneID:4775 -> Biological process: GO:0006357 [regulation of transcription from RNA polymerase II promoter] evidence: TAS
            GeneID:4775 -> Biological process: GO:0006366 [transcription from RNA polymerase II promoter] evidence: TAS
            GeneID:4775 -> Biological process: GO:0006954 [inflammatory response] evidence: TAS
            GeneID:4775 -> Biological process: GO:0007507 [heart development] evidence: IEA
            GeneID:4775 -> Biological process: GO:0038095 [Fc-epsilon receptor signaling pathway] evidence: TAS
            GeneID:4775 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
            GeneID:4775 -> Biological process: GO:0045333 [cellular respiration] evidence: IEA
            GeneID:4775 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IDA
            GeneID:4775 -> Biological process: GO:0051145 [smooth muscle cell differentiation] evidence: IEA
            GeneID:4775 -> Biological process: GO:0055001 [muscle cell development] evidence: IEA
            GeneID:4775 -> Biological process: GO:0071285 [cellular response to lithium ion] evidence: IEA
            GeneID:4775 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:4775 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
            GeneID:4775 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
            GeneID:4775 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
            GeneID:4775 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:4775 -> Cellular component: GO:0005886 [plasma membrane] evidence: IDA

by @meso_cacase at DBCLS
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