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2019-03-23 03:27:06, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_004379               9752 bp    mRNA    linear   PRI 26-MAY-2013
DEFINITION  Homo sapiens cAMP responsive element binding protein 1 (CREB1),
            transcript variant A, mRNA.
ACCESSION   NM_004379
VERSION     NM_004379.3  GI:215490111
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 9752)
  AUTHORS   Hoang,T., Fenne,I.S., Madsen,A., Bozickovic,O., Johannessen,M.,
            Bergsvag,M., Lien,E.A., Stallcup,M.R., Sagen,J.V., Moens,U. and
            Mellgren,G.
  TITLE     cAMP response element-binding protein interacts with and stimulates
            the proteasomal degradation of the nuclear receptor coactivator
            GRIP1
  JOURNAL   Endocrinology 154 (4), 1513-1527 (2013)
   PUBMED   23462962
  REMARK    GeneRIF: cAMP response element-binding protein (CREB) downregulates
            GRIP1 and is necessary for the PKA-stimulated degradation of GRIP1,
            which leads to changes in the expression of a subset of genes
            regulated by estrogen receptor-alpha in MCF-7 breast cancer cells.
REFERENCE   2  (bases 1 to 9752)
  AUTHORS   Shimizu,A., Nakayama,H., Wang,P., Konig,C., Akino,T., Sandlund,J.,
            Coma,S., Italiano,J.E. Jr., Mammoto,A., Bielenberg,D.R. and
            Klagsbrun,M.
  TITLE     Netrin-1 promotes glioblastoma cell invasiveness and angiogenesis
            by multiple pathways including activation of RhoA, cathepsin B, and
            cAMP-response element-binding protein
  JOURNAL   J. Biol. Chem. 288 (4), 2210-2222 (2013)
   PUBMED   23195957
  REMARK    GeneRIF: Netrin-1 promotes glioblastoma cell invasiveness and
            angiogenesis by multiple pathways including activation of RhoA,
            cathepsin B, and cAMP-response element-binding protein
REFERENCE   3  (bases 1 to 9752)
  AUTHORS   Luo,Q., Viste,K., Urday-Zaa,J.C., Senthil Kumar,G., Tsai,W.W.,
            Talai,A., Mayo,K.E., Montminy,M. and Radhakrishnan,I.
  TITLE     Mechanism of CREB recognition and coactivation by the
            CREB-regulated transcriptional coactivator CRTC2
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 109 (51), 20865-20870 (2012)
   PUBMED   23213254
  REMARK    GeneRIF: Mechanism of CREB recognition and coactivation by the
            CREB-regulated transcriptional coactivator CRTC2
REFERENCE   4  (bases 1 to 9752)
  AUTHORS   Tan,X., Wang,S., Yang,B., Zhu,L., Yin,B., Chao,T., Zhao,J.,
            Yuan,J., Qiang,B. and Peng,X.
  TITLE     The CREB-miR-9 negative feedback minicircuitry coordinates the
            migration and proliferation of glioma cells
  JOURNAL   PLoS ONE 7 (11), E49570 (2012)
   PUBMED   23185366
  REMARK    GeneRIF: CREB-miR-9 negative feedback minicircuitry coordinates the
            migration and proliferation of glioma cells
REFERENCE   5  (bases 1 to 9752)
  AUTHORS   Li,Y., Shaw,C.A., Sheffer,I., Sule,N., Powell,S.Z., Dawson,B.,
            Zaidi,S.N., Bucasas,K.L., Lupski,J.R., Wilhelmsen,K.C., Doody,R.
            and Szigeti,K.
  TITLE     Integrated copy number and gene expression analysis detects a CREB1
            association with Alzheimer's disease
  JOURNAL   Transl Psychiatry 2, E192 (2012)
   PUBMED   23168992
  REMARK    GeneRIF: Copy number variation upstream of CREB1 was associated
            with Alzheimer disease.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 9752)
  AUTHORS   Meyer,T.E. and Habener,J.F.
  TITLE     Cyclic AMP response element binding protein CREB and modulator
            protein CREM are products of distinct genes
  JOURNAL   Nucleic Acids Res. 20 (22), 6106 (1992)
   PUBMED   1461747
REFERENCE   7  (bases 1 to 9752)
  AUTHORS   Zhao,L.J. and Giam,C.Z.
  TITLE     Human T-cell lymphotropic virus type I (HTLV-I) transcriptional
            activator, Tax, enhances CREB binding to HTLV-I 21-base-pair
            repeats by protein-protein interaction
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 89 (15), 7070-7074 (1992)
   PUBMED   1386673
REFERENCE   8  (bases 1 to 9752)
  AUTHORS   Rehfuss,R.P., Walton,K.M., Loriaux,M.M. and Goodman,R.H.
  TITLE     The cAMP-regulated enhancer-binding protein ATF-1 activates
            transcription in response to cAMP-dependent protein kinase A
  JOURNAL   J. Biol. Chem. 266 (28), 18431-18434 (1991)
   PUBMED   1655749
REFERENCE   9  (bases 1 to 9752)
  AUTHORS   Short,M.L., Manohar,C.F., Furtado,M.R., Ghadge,G.D., Wolinsky,S.M.,
            Thimmapaya,B. and Jungmann,R.A.
  TITLE     Nucleotide and derived amino-acid sequences of the CRE-binding
            proteins from rat C6 glioma and HeLa cells
  JOURNAL   Nucleic Acids Res. 19 (15), 4290 (1991)
   PUBMED   1831258
REFERENCE   10 (bases 1 to 9752)
  AUTHORS   Waeber,G., Meyer,T.E., Hoeffler,J.P. and Habener,J.F.
  TITLE     Diversification of cyclic AMP-responsive enhancer binding
            proteins-generated by alternative exon splicing
  JOURNAL   Trans. Assoc. Am. Physicians 103, 28-37 (1990)
   PUBMED   1966745
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DC366797.1, BC095407.1,
            AC079767.7 and AW205606.1.
            On Dec 3, 2008 this sequence version replaced gi:22219459.
            
            Summary: This gene encodes a transcription factor that is a member
            of the leucine zipper family of DNA binding proteins. This protein
            binds as a homodimer to the cAMP-responsive element, an octameric
            palindrome. The protein is phosphorylated by several protein
            kinases, and induces transcription of genes in response to hormonal
            stimulation of the cAMP pathway. Alternate splicing of this gene
            results in two transcript variants encoding different isoforms.
            [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (A) lacks an in-frame exon in the
            coding region, compared to variant B. Isoform A is shorter compared
            to isoform B.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            transcript and genomic sequence to make the sequence consistent
            with the reference genome assembly. The genomic coordinates used
            for the transcript record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC095407.1, M27691.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025082 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-56                DC366797.1         1-56
            57-2661             BC095407.1         1-2605
            2662-9256           AC079767.7         8439-15033
            9257-9752           AW205606.1         1-496               c
FEATURES             Location/Qualifiers
     source          1..9752
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q34"
     gene            1..9752
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /note="cAMP responsive element binding protein 1"
                     /db_xref="GeneID:1385"
                     /db_xref="HGNC:2345"
                     /db_xref="HPRD:00442"
                     /db_xref="MIM:123810"
     exon            1..243
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /inference="alignment:Splign:1.39.8"
     STS             166..898
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /standard_name="Creb1"
                     /db_xref="UniSTS:527295"
     variation       181
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1050641"
     exon            244..365
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    249..251
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /note="upstream in-frame stop codon"
     CDS             252..1235
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /note="isoform A is encoded by transcript variant A;
                     cAMP-response element-binding protein-1; active
                     transcription factor CREB; transactivator protein; cyclic
                     AMP-responsive element-binding protein 1; CREB-1;
                     cAMP-responsive element-binding protein 1"
                     /codon_start=1
                     /product="cyclic AMP-responsive element-binding protein 1
                     isoform A"
                     /protein_id="NP_004370.1"
                     /db_xref="GI:4758054"
                     /db_xref="CCDS:CCDS2374.1"
                     /db_xref="GeneID:1385"
                     /db_xref="HGNC:2345"
                     /db_xref="HPRD:00442"
                     /db_xref="MIM:123810"
                     /translation="
MTMESGAENQQSGDAAVTEAENQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLANNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD
"
     misc_feature    540..542
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /db_xref="HPRD:06347"
     misc_feature    570..572
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /db_xref="HPRD:06347"
     misc_feature    <576..662
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /note="pKID domain; Region: pKID; pfam02173"
                     /db_xref="CDD:145367"
     misc_feature    594..596
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /db_xref="HPRD:05418"
     misc_feature    606..608
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    606..608
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /db_xref="HPRD:04264"
     misc_feature    1050..1232
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /note="bZIP transcription factor; Region: bZIP_1;
                     pfam00170"
                     /db_xref="CDD:201054"
     variation       259..260
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:35318842"
     variation       273
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367727829"
     variation       318
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:56292136"
     variation       326
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370037055"
     variation       354
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114514847"
     exon            366..512
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /inference="alignment:Splign:1.39.8"
     variation       388
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143117860"
     variation       407
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140357947"
     variation       430
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374575266"
     variation       434
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:35349697"
     variation       467
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:78701038"
     variation       475
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:376460743"
     exon            513..613
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /inference="alignment:Splign:1.39.8"
     variation       556
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:387906617"
     exon            614..756
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /inference="alignment:Splign:1.39.8"
     variation       716
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201642429"
     exon            757..939
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /inference="alignment:Splign:1.39.8"
     variation       803
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376739437"
     variation       824
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111280106"
     variation       833
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:56020464"
     variation       930
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147363050"
     exon            940..1090
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /inference="alignment:Splign:1.39.8"
     variation       959
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:74338269"
     variation       989
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370046152"
     variation       1016
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373274620"
     exon            1091..9737
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /inference="alignment:Splign:1.39.8"
     variation       1112
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145164313"
     variation       1127
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140407055"
     variation       1157
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113621918"
     variation       1159
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:76312267"
     variation       1194
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113145794"
     variation       1279
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372883715"
     variation       1280
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375322973"
     polyA_signal    1303..1308
                     /gene="CREB1"
                     /gene_synonym="CREB"
     STS             1322..1423
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /standard_name="D2S2634"
                     /db_xref="UniSTS:947"
     polyA_site      1349
                     /gene="CREB1"
                     /gene_synonym="CREB"
     variation       1452
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:192082921"
     variation       1498
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:56267720"
     STS             1516..2390
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /standard_name="CREB1_v456"
                     /db_xref="UniSTS:277126"
     variation       1574
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:182906174"
     variation       1626
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:143587811"
     variation       1675
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:75550279"
     variation       1731
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:188411162"
     variation       1773
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191157228"
     variation       1874
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371836046"
     STS             1885..1981
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /standard_name="RH67919"
                     /db_xref="UniSTS:28279"
     variation       2042
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:56390214"
     variation       2044
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:55879019"
     variation       2063
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:182205610"
     variation       2065
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:372808746"
     polyA_signal    2105..2110
                     /gene="CREB1"
                     /gene_synonym="CREB"
     polyA_site      2134
                     /gene="CREB1"
                     /gene_synonym="CREB"
     variation       2157
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:79271892"
     variation       2180
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:187559873"
     variation       2347
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:368510478"
     variation       2357
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:192450396"
     variation       2385
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:185867924"
     variation       2395
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:56291091"
     variation       2432
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:56299306"
     variation       2526..2527
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="ta"
                     /db_xref="dbSNP:374093740"
     variation       2536
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375850822"
     variation       2664..2666
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="aaa"
                     /db_xref="dbSNP:200878580"
     variation       2664..2665
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="aa"
                     /db_xref="dbSNP:143222694"
     variation       2664
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="aa"
                     /db_xref="dbSNP:10568689"
     variation       2723
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:184610034"
     variation       2746
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:73056958"
     variation       2794
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:150397030"
     variation       2906
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:138437655"
     variation       2973
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143910207"
     variation       2997
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146786929"
     variation       3027
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:201051271"
     variation       3028
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:11319861"
     variation       3028
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:199698025"
     variation       3077
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:79736988"
     variation       3113
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:76511710"
     variation       3129
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139198232"
     variation       3172
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:56325368"
     variation       3245
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:12998128"
     variation       3331
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:188764041"
     variation       3377
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374925108"
     variation       3392
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:143340162"
     variation       3518
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377363594"
     variation       3704
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:180685015"
     variation       3724
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:372887564"
     variation       3744
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:78823096"
     variation       3757
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369543832"
     variation       3867
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:35836086"
     variation       4039
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:188447438"
     variation       4324
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371052022"
     variation       4415..4416
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="atat"
                     /db_xref="dbSNP:71412422"
     variation       4415
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375493613"
     variation       4416..4419
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="atat"
                     /db_xref="dbSNP:72442628"
     variation       4416..4417
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="at"
                     /replace="atat"
                     /db_xref="dbSNP:71786143"
     variation       4426..4427
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="at"
                     /db_xref="dbSNP:72062178"
     variation       4440..4441
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="tata"
                     /db_xref="dbSNP:71036937"
     variation       4455
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:148160448"
     variation       4845
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:182101766"
     variation       4997
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:13029936"
     variation       4999
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114892556"
     variation       5102
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:116076718"
     variation       5165..5166
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="tc"
                     /db_xref="dbSNP:34171849"
     variation       5166..5167
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="ct"
                     /db_xref="dbSNP:10559988"
     variation       5167..5172
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="tctgtt"
                     /db_xref="dbSNP:199601798"
     variation       5167..5168
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="ct"
                     /db_xref="dbSNP:72544077"
     variation       5167
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201988867"
     variation       5168
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:201754017"
     variation       5188
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141652982"
     variation       5223
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150506251"
     variation       5225
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139870509"
     variation       5231
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2551928"
     variation       5302..5305
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="ttta"
                     /db_xref="dbSNP:139164200"
     variation       5302
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="ttta"
                     /db_xref="dbSNP:5838080"
     variation       5305..5308
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="attt"
                     /db_xref="dbSNP:376057671"
     variation       5305
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:200703008"
     variation       5305
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="attt"
                     /db_xref="dbSNP:10559989"
     variation       5307
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200838888"
     variation       5392
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111992031"
     variation       5398
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:187594841"
     variation       5618
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:191527208"
     variation       5659
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181966687"
     variation       5714..5718
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="ctcaa"
                     /db_xref="dbSNP:375357358"
     variation       5723
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1806584"
     variation       5819
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1806585"
     variation       5893
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:185366371"
     variation       5906
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:56129159"
     variation       6017
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:143220643"
     variation       6030..6031
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:35856558"
     variation       6066
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:190175450"
     variation       6086
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:146249401"
     variation       6092
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="ttaag"
                     /db_xref="dbSNP:112958608"
     variation       6109..6110
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="tg"
                     /db_xref="dbSNP:200579743"
     variation       6162
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:139271055"
     variation       6180
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149927228"
     variation       6257
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:111842669"
     variation       6281
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:182658728"
     variation       6481
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:377737239"
     variation       6603
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1045780"
     variation       6673
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149111106"
     variation       6726
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:13386109"
     variation       6882
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186586133"
     polyA_signal    6916..6921
                     /gene="CREB1"
                     /gene_synonym="CREB"
     polyA_site      6945
                     /gene="CREB1"
                     /gene_synonym="CREB"
     variation       6983
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:189904488"
     variation       7031
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:183832672"
     variation       7154
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373213291"
     variation       7212
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:12999688"
     variation       7250
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1045790"
     variation       7265
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:115526431"
     variation       7450
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:6785"
     variation       7453
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:189094154"
     variation       7538
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:192810631"
     variation       7642
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147657658"
     variation       7925
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2551929"
     variation       7952
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142438869"
     variation       8016..8017
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:376856014"
     variation       8064
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146501770"
     variation       8078
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139123873"
     variation       8196..8198
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="caa"
                     /db_xref="dbSNP:371137073"
     variation       8217
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374059381"
     variation       8248
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140564236"
     variation       8264
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35371479"
     variation       8317
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185369978"
     variation       8345
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:187039760"
     variation       8367
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370775575"
     variation       8418
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191720781"
     variation       8498
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:55694411"
     variation       8511..8515
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="aactt"
                     /db_xref="dbSNP:138273242"
     variation       8578
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:61058659"
     variation       8591
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:150454556"
     variation       8597
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184271497"
     STS             8615..8745
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /standard_name="SGC35219"
                     /db_xref="UniSTS:61462"
     variation       8637
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2256941"
     variation       8641
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138348185"
     variation       8667..8670
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="aaga"
                     /db_xref="dbSNP:4025849"
     variation       8671
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:75167578"
     variation       8672..8673
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="ag"
                     /db_xref="dbSNP:4025848"
     variation       8711
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:116590105"
     variation       8756
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:149629990"
     variation       8783
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369869267"
     variation       8848..8850
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="acc"
                     /db_xref="dbSNP:147476972"
     variation       8850..8852
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="cac"
                     /db_xref="dbSNP:368442759"
     variation       8852
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188266883"
     variation       8928
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:181042336"
     variation       8930
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:78913180"
     variation       8936
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:185392351"
     variation       8955
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:58914399"
     variation       8982
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368788833"
     variation       9038
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2551930"
     variation       9097
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:190734638"
     variation       9110
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374469647"
     variation       9199
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181529395"
     variation       9294
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:185814853"
     variation       9449..9450
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="tc"
                     /db_xref="dbSNP:142169610"
     variation       9460
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145940427"
     variation       9627
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:190615978"
     variation       9634
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367769465"
     variation       9703..9704
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:374747042"
     variation       9712
                     /gene="CREB1"
                     /gene_synonym="CREB"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369125242"
ORIGIN      
tgtttccgtgcgcggccgctgcgcactcggcactgggcggcgctggctggctccctggctgcggctcctcagtcggcggcggctgctgctgcctgtggcccgggcggctgggagaagcggagtgttggtgagtgacgcggcggaggtgtagtttgacgcggtgtgttacgtgggggagagaataaaactccagcgagatccgggccgtgaacgaaagcagtgacggaggagcttgtaccaccggtaactaaatgaccatggaatctggagccgagaaccagcagagtggagatgcagctgtaacagaagctgaaaaccaacaaatgacagttcaagcccagccacagattgccacattagcccaggtatctatgccagcagctcatgcaacatcatctgctcccaccgtaactctagtacagctgcccaatgggcagacagttcaagtccatggagtcattcaggcggcccagccatcagttattcagtctccacaagtccaaacagttcagatttcaactattgcagaaagtgaagattcacaggagtcagtggatagtgtaactgattcccaaaagcgaagggaaattctttcaaggaggccttcctacaggaaaattttgaatgacttatcttctgatgcaccaggagtgccaaggattgaagaagagaagtctgaagaggagacttcagcacctgccatcaccactgtaacggtgccaactccaatttaccaaactagcagtggacagtatattgccattacccagggaggagcaatacagctggctaacaatggtaccgatggggtacagggcctgcaaacattaaccatgaccaatgcagcagccactcagccgggtactaccattctacagtatgcacagaccactgatggacagcagatcttagtgcccagcaaccaagttgttgttcaagctgcctctggagacgtacaaacataccagattcgcacagcacccactagcactattgcccctggagttgttatggcatcctccccagcacttcctacacagcctgctgaagaagcagcacgaaagagagaggtccgtctaatgaagaacagggaagcagctcgagagtgtcgtagaaagaagaaagaatatgtgaaatgtttagaaaacagagtggcagtgcttgaaaatcaaaacaagacattgattgaggagctaaaagcacttaaggacctttactgccacaaatcagattaatttgggatttaaattttcacctgttaaggtggaaaatggactggcttggccacaacctgaaagacaaaataaacattttattttctaaacatttctttttttctatgcgcaaaactgcctgaaagcaactacagaatttcattcatttgtgcttttgcattaaactgtgaatgttccaacacctgcctccacttctcccctcaagaaattttcaacgccaggaatcatgaagagacttctgcttttcaacccccaccctcctcaagaagtaataatttgtttacttgtaaattgatgggagaaatgaggaaaagaaaatctttttaaaaatgatttcaaggtttgtgctgagctccttgattgccttagggacagaattaccccagcctcttgagctgaagtaatgtgtgggccgcatgcataaagtaagtaaggtgcaatgaagaagtgttgattgccaaattgacatgttgtcacattctcattgtgaattatgtaaagttgttaagagacataccctctaaaaaagaactttagcatggtattgaaggaattagaaatgaatttggagtgctttttatgtatgttgtcttcttcaatactgaaaatttgtccttggttcttaaaagcattctgtactaatacagctcttccatagggcagttgttgcttcttaattcagttctgtatgtgttcaacatttttgaatacattaaaagaagtaaccaactgaacgacaaagcatggtatttgaattttaaattaaagcaaagtaaataaaagtacaaagcatattttagttagtactaaattcttagtaaaatgctgatcagtaaaccaatcccttgagttatataacaagatttttaaataaatgttattgtcctcaccttcaaaaatatttatattgtcactcatttacgtaaaaagatatttctaatttactgttgcccattgcacttacataccaccaccaagaaagccttcaagatgtcaaataaagcaaagtgatatatatttgtttatgaaatgttacatgtagaaaaatactgattttaaatattttccatattaacaatttaacagagaatctctagtgaattttttaaatgaaagaagttgtaaggatataaaaagtacagtgttagatgtgcacaaggaaagttattttcagacatatttgaatgactgctgtactgcaatatttggattgtcattcttacaaaacatttttttgttctcttgtaaaaagagtagttattagttctgctttagctttccaatatgctgtatagcctttgtcattttataattttaattcctgattaaaacagtctgtatttgtgtatatcatacattgttttcaataccacttttaattgttactcattttattcactaagctcgataaatctaacagttactcttaaaaaaaaaaaaaaaagactaaggtggattttaaaaattggaaactgacataatgttaggttataatttctcatttggagccgggcgcagtggctcacgcctgtaatcccagcactttgggaggccaaggtgggtggatcacctgtggtcaagagttcaagaccagcctggccatcatggtgaaaccccatctctactaaaaatacaaaaattagccaggcgtggtggctggcgcctgtaatcccagctactcaggaggttgaggcagcagaattgcttgaacccaggaggcagagggttgcagtgagccgagatagcaccattgcactccagcctgggcgactccatctcaaaaaataaaaataaaaaaaatgtctcatttgggaaggaaattccttttaaaaaagagttgagacacttagaaaactaatgttttatatttagtcaagagttatttaagaaagtcaagcttgtttaacaacaaaatatgaagatttaagtgttaattgctggatccattttaaaataagattttaattaacatttgtaaatggtatattttcgtttgtaacaaaccattgtcttttttcaaggatgaacagagtttatgaaggagcatcattctaagaattaagtgatgtagtctttatgtttggacagttcaccagattctcaagaaggctttcaaacaactataaagtttgatgtttgtcctgctgagctaatggggaaagttatagcataaaaattgtgtaaccgcatagatatgtcatttttaaaaactggtttaacagaaatcaagcaaagtcacaaatatgttcacaagttggaattatttattgagtcaaaatgtcgaatcgaacattttgaatgaagtaagtgttataaatgaaaaattgcctgatgtttagcagtttgtattctctaaagctttttttcaaaagttcaggctttctacttactgggaagttggtggtcctcttagtccctgataaatcaaggcaatcacattcatgtgagctggatgaatttataagttataaagaccttatccttcataccttgaggatgattgcactggttttgaagtcagttgcttaatgatgaggtgagaaatgtatcctgttgctaaatctgtcttagacccttggtgaaacttgaagatttcagtttataaagataaaatcaagcatcttttgtgcagttttctttttttaatgcaagaatggtggggaggtttgtttgtaagcatgaaactttgagaatctttattaagaaaatgacataatttttaaaaaccttgtagccaagaacatatgtggccacattaccagtaataaatgtttttctctttatattggccaaaagggaataaaaatgtcatcataggaatttgtacatatgctactgatttgcctagaaaatagcaagtttgatattgctcactttgcaaatatagggccatgtggcacttttatctataggacagattaataaaaatgaagtggggaggggtttatttttgatatattactcttatgagttttcaagctttgataatgtttaactgaaaagtggcttagaaagggctagatccaatgtgttcattattaaataattgctatcagatacaattttaagttcattctttttcaaactcaagtaccatattggcaaccataatattgtcataggtgctctcttcatttagatattcttggggggggtggcatttgtataatatatgtgtacatatatatatatatatatatatatacatacagtatataatctaaagctctgagagctcttaagtcaggaatgctgagtattatagtatattgaggtcagatgaaattttacatttttgtgtgttctgttgcattccttctggtagtttctatgactgcattactccagcactcatgattgattttatcttctaattttcttccaagtattttattttttattagttttctttggcttgatacttttaaatatgttactagtcacttgaaagcctctcccccaaaagtatttggtttgtatgctttgtctgtggcagctataacagtggtaagaacattttgaagatagctttttaaaggaaccactgattttttcaaaaatcatcctgggggaggaattttggcatttcatttgagcagggattttgtcagaaaatgtgttttgatggtaggtcagcagcagtgctagtctctgaaagcacaataccagtcaggcagcctatcccatcagatgtcatctggctgaagtttatctctgtctctcaggataaatccctgtaggacaaatccctactatcatttctaccttttggggtgacatgtggaatcatacaaaggcttaggaagaaatacgtttgtttaaaccaggatgctttacttacttgaagtgacttcaatctagatttcttttaatatttaacaaatttttaattctatgatcagccacagtcagctattaccataaattggtctctgtttattttgaagatcacggctgcttcattttgcaggattaagtagggctaatgtatcttaaagttaagatcttgaattaaagtgagttttagaaatagtgttacataccttttcagttgttttcaagaggctttatttttgttgcctttgtagccctgaaagctgttggtatattttttccctcatggacccaatagaaaagttgtatatttatttggattatatttacattctgtcctttgtaaatgtttggtgtaacttgcacttttttaaatgacccagtttgggtattagcaacttaagaaattccctcatcaagtaattctcaactttttagtctttctcctctcttcaaatcatgtgactttttaaatggaagtttttcattgattaaaatattttagcacctaaaagctagccttaaaaacagctgtaaaagaaaaacatcaggaaattagatatgactagcccagttaattaaaagacgggctcaaaccttgttttattctttttcatcttggatgaagattgaagggaaaataactcaagtgcataatatttattttcaatttttaatgagactttatcctcatcacaacattaatactgtacatagtatgccaaaatatccattaatttgtctagaatagtacaagactttttaaagcaattgtcctcacagagaccacatgtaatatactgaaatatgttcatttttaatggctttgttaacatcaaagaaatgctgcctaaatttgatttcagatgaggaaggagaaagtaaagtgtgcatagtaaggctgtaggtgaagagttgtgagataaatagttcactcagttgtacaaagcacaactagaactttttgttgggaggcttacatacatcttgaatattcttaatgtaataatgttgactattaagttggctacacagtcactgtatgtactaggaactggtttccttgacattctagaatcaatggctaggagaggcattaatctttgaggggctgaacatatcatgaagctgagtcagtatggaaaattttcaaataaacagggtgctgaagttccatctgtctcatctgcttatgataagttcttattgattagtgaatgtagcttaagcctttgtatgtgtcctcagggggcagaccgactttaagagggaccagataacgtttgaatggagggattatatttcaggtgttttagcttgaaatttattttttaaaaaaagaaaaatttaaaaaatatataaataaaatagaacaaagccggtgatgcaagttgatattataaacaggcagttttagcacagaaagaaaatactgacctgtctgcattctggtacggtgggtgcaggtcccagctgggtatgacatgatacatttttaattattctcaccagcaagtaaaaggaaaatgaacaatcttttggaattgtctttgaaaaggatcaaagagtaggaaattcacatttgacctaacattacttgcctatagaagtatggcatttccaagcttttgtctgaggagcatctcagagaagtgagagtaaatctgagttagcttaaaaattggtagggaggaagaaaatctctgcaaataatgattttatgtttgttggccaagtgaaatgatctatcattgtgtttgggaggttttattttcttatgtttttaaaattggtaaatgctttatagatgtatttttatccaagtgccactccaatttgtgtatgtaataaaattatttatattaaaagtgggaaataattgtcaacattttttttgagtatagatttattaggggtggcaaagaagagtgctagttagcagttttccatgtaaagttgtccttgactgatttgtccacatgtcagttgtaactcccccactccctgcaaaaggaattatttctaacccagatgtatcacttgaaactttttagaagcaaaataatcagggaagttcctagaaaggtgtttggctttttggtttttgagggttggggtaaagaagacttcccccacaactgtcagcacaaaacagggtattgatttttaactctgatgtttctattggagttgaatactaaataaataactataatgagggaaatacatttctaataaaattccctacattctagaaacatccctgttttaatttttttatctaaatctttttgtgctttatgtgtaaagaaaaaaatgtactgagttacaatgcattttattaacactatgtacataatagctgctttgtgttcagaatagtagcagttgctttgtatattaaagtgatccttgtgaatttgtgaaatattgtcataaagtgctttttcttactgtaatctttgtggtatcaactgtcataatgctctttttacacaaacatttatgtgcagtcacataaacatgcttttaaaaactctgtaagtctcttttttggggatgggatctctatattttgttgggttttttttgctagtagtgtgaagccatgttttattggacttaaagttacaatatattacaagcttgtgttggaaggcagcaaaactaattcagacaacaacatgtcttcagttactggatccctaattttcaggacaaaacctgtttttcaataagattgaacagtgcctatttgtggatttggagatgttactgtcaagatgactaatggagacatacgaccagctgtgtctgatgtcataaaacacgtgttcactgaaaggacaataagactatataccttctcaggtccccttgcaattctaaaactctgtgatcatataaattggaaggaaaggggaggggatatggttaatctttgcttaagctgtaagaataaaaaagttatctcctatactattaacttctgaaataagttctgagacgagacatctgaaaataagcagctgcattatttgtatgtttcttcactgccaagatgtgttcaagcctgctatacctgccattgtattggaaggcttaatgaatttcatttattttctgcaacaacgattacagaatttattgcacaaaatgagacattttgagagtgatattaattacatgagggacaataggcatgaactaggattgttctaagcaaatcggaatcgggtcaccctgccacgttcaggtgcttggaccttcaggaaaagattgcccatcttgtcatttgaccaggcactgaagtgacaagaccatccttgagaagtcacatccaaagataaaattctgatccatttctagttttagtgtttcgccactgaagacttaacatatgtcttttacactcaggttgcaaaacacaggcccaagacaaacttaacttctcccccaaatcttccttccgctggtttttccatctcgtaagtggtgccactatccatctgttaaattgtttaggggaaacctagaaaagcactaccttaatcagtgttatccttcttcttaactgtgcgtcctaatttctccacatctttcttaagtgcagtgaccaaaccggatgagaattctaacacgggcctgacatcaaatggaaaggaaggataatgtccaggagttggaatgttatccttgtttttaattaagatgcaattcacataaattaactttttaagtgaacaattaagtggtagtacatccacaatggtgtacaaccaccacttctatctagctccaaaacattctcatcactccaaaagtaaagtcccgttactctccattttctcctcccaccgcccttgtccctggcaaccaccaatctgcttcctgtttctttggatttacatccgggtatttcatgtgagactcatacactgtgtattacttctttcgtctagctttaatgtgttgttgaggttgatccattgtaacatgttatcactacttcattcctttttatagctaagtatactttttatagtaagtatgccattgtagatatataccacaagtttatcgattcatccagttgagttgtttctactgtttggctaatgttcatagtgctgttatgaatgttcgtgtacaagtatttgagtccgtgttttcaattatttggggtatatgcctgggagtggagttgctgggtcatgttgaaatcgcacatttaactttttgaggaactgtcaaactttccctcagcagctgtaccgttttaccttccaccattgatgtatgagggttccaatttctccacaccttcaccaacacttattttgccattttaaaaattatagccatcctcatgggtgtggtctctcattgtggttttgatttgcatttccctgattactaatgatgtggagcatcttttgttgtctttggccatctgcgtatcttctttgaagaaatgtctgttgaggtcctttgttcattgaaattttgttgttgggttctgagttccttatatattctgggtactaggcccttataatattttcgcctataagtttttgctttataatgtcctcattgttttcaaacttactttatgtaatatgtacacttctaaaaaaaagaaacatggaaaagggcaaactgtaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:1385 -> Molecular function: GO:0000980 [RNA polymerase II distal enhancer sequence-specific DNA binding] evidence: IDA
            GeneID:1385 -> Molecular function: GO:0001102 [RNA polymerase II activating transcription factor binding] evidence: IPI
            GeneID:1385 -> Molecular function: GO:0001190 [RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription] evidence: IDA
            GeneID:1385 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IDA
            GeneID:1385 -> Molecular function: GO:0003705 [RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity] evidence: IDA
            GeneID:1385 -> Molecular function: GO:0003712 [transcription cofactor activity] evidence: TAS
            GeneID:1385 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:1385 -> Molecular function: GO:0035497 [cAMP response element binding] evidence: IDA
            GeneID:1385 -> Biological process: GO:0002224 [toll-like receptor signaling pathway] evidence: TAS
            GeneID:1385 -> Biological process: GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] evidence: TAS
            GeneID:1385 -> Biological process: GO:0002756 [MyD88-independent toll-like receptor signaling pathway] evidence: TAS
            GeneID:1385 -> Biological process: GO:0006468 [protein phosphorylation] evidence: IDA
            GeneID:1385 -> Biological process: GO:0007165 [signal transduction] evidence: TAS
            GeneID:1385 -> Biological process: GO:0007173 [epidermal growth factor receptor signaling pathway] evidence: TAS
            GeneID:1385 -> Biological process: GO:0007202 [activation of phospholipase C activity] evidence: TAS
            GeneID:1385 -> Biological process: GO:0007219 [Notch signaling pathway] evidence: TAS
            GeneID:1385 -> Biological process: GO:0007268 [synaptic transmission] evidence: TAS
            GeneID:1385 -> Biological process: GO:0007411 [axon guidance] evidence: TAS
            GeneID:1385 -> Biological process: GO:0007595 [lactation] evidence: IEA
            GeneID:1385 -> Biological process: GO:0008361 [regulation of cell size] evidence: IEA
            GeneID:1385 -> Biological process: GO:0008543 [fibroblast growth factor receptor signaling pathway] evidence: TAS
            GeneID:1385 -> Biological process: GO:0010033 [response to organic substance] evidence: IDA
            GeneID:1385 -> Biological process: GO:0010944 [negative regulation of transcription by competitive promoter binding] evidence: IDA
            GeneID:1385 -> Biological process: GO:0019048 [modulation by virus of host morphology or physiology] evidence: IEA
            GeneID:1385 -> Biological process: GO:0021983 [pituitary gland development] evidence: IEA
            GeneID:1385 -> Biological process: GO:0033363 [secretory granule organization] evidence: IEA
            GeneID:1385 -> Biological process: GO:0034134 [toll-like receptor 2 signaling pathway] evidence: TAS
            GeneID:1385 -> Biological process: GO:0034138 [toll-like receptor 3 signaling pathway] evidence: TAS
            GeneID:1385 -> Biological process: GO:0034142 [toll-like receptor 4 signaling pathway] evidence: TAS
            GeneID:1385 -> Biological process: GO:0034146 [toll-like receptor 5 signaling pathway] evidence: TAS
            GeneID:1385 -> Biological process: GO:0034162 [toll-like receptor 9 signaling pathway] evidence: TAS
            GeneID:1385 -> Biological process: GO:0034166 [toll-like receptor 10 signaling pathway] evidence: TAS
            GeneID:1385 -> Biological process: GO:0035666 [TRIF-dependent toll-like receptor signaling pathway] evidence: TAS
            GeneID:1385 -> Biological process: GO:0038095 [Fc-epsilon receptor signaling pathway] evidence: TAS
            GeneID:1385 -> Biological process: GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] evidence: TAS
            GeneID:1385 -> Biological process: GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] evidence: TAS
            GeneID:1385 -> Biological process: GO:0040018 [positive regulation of multicellular organism growth] evidence: IEA
            GeneID:1385 -> Biological process: GO:0042493 [response to drug] evidence: IEA
            GeneID:1385 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
            GeneID:1385 -> Biological process: GO:0045600 [positive regulation of fat cell differentiation] evidence: ISS
            GeneID:1385 -> Biological process: GO:0045893 [positive regulation of transcription, DNA-dependent] evidence: ISS
            GeneID:1385 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IDA
            GeneID:1385 -> Biological process: GO:0046887 [positive regulation of hormone secretion] evidence: IEA
            GeneID:1385 -> Biological process: GO:0046889 [positive regulation of lipid biosynthetic process] evidence: ISS
            GeneID:1385 -> Biological process: GO:0048011 [neurotrophin TRK receptor signaling pathway] evidence: TAS
            GeneID:1385 -> Biological process: GO:0048015 [phosphatidylinositol-mediated signaling] evidence: TAS
            GeneID:1385 -> Biological process: GO:0050821 [protein stabilization] evidence: ISS
            GeneID:1385 -> Biological process: GO:0051403 [stress-activated MAPK cascade] evidence: TAS
            GeneID:1385 -> Biological process: GO:0060430 [lung saccule development] evidence: IEA
            GeneID:1385 -> Biological process: GO:0060509 [Type I pneumocyte differentiation] evidence: IEA
            GeneID:1385 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:1385 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
            GeneID:1385 -> Cellular component: GO:0005667 [transcription factor complex] evidence: IEA
            GeneID:1385 -> Cellular component: GO:0005719 [nuclear euchromatin] evidence: IDA
            GeneID:1385 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA

by @meso_cacase at DBCLS
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