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2024-04-26 01:10:00, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_004271 895 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens lymphocyte antigen 86 (LY86), mRNA.
ACCESSION NM_004271
VERSION NM_004271.3 GI:55775471
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 895)
AUTHORS Ohto,U., Miyake,K. and Shimizu,T.
TITLE Crystal structures of mouse and human RP105/MD-1 complexes reveal
unique dimer organization of the toll-like receptor family
JOURNAL J. Mol. Biol. 413 (4), 815-825 (2011)
PUBMED 21959264
REMARK GeneRIF: Both mouse and human RP105/MD-1 exhibit dimerization of
the 1:1 RP105/MD-1 complex, demonstrating a novel organization.
REFERENCE 2 (bases 1 to 895)
AUTHORS Mengwasser,K.E., Bryant,C.E., Gay,N.J. and Gangloff,M.
TITLE LPS ligand and culture additives improve production of monomeric
MD-1 and 2 in Pichia pastoris by decreasing aggregation and
intermolecular disulfide bonding
JOURNAL Protein Expr. Purif. 76 (2), 173-183 (2011)
PUBMED 21130168
REMARK GeneRIF: In this study, we produced variants of MD-1 and MD-2 in
Pichia pastoris. Contrary to previous reports, this study suggests
that MD-1 can bind to LPS.
REFERENCE 3 (bases 1 to 895)
AUTHORS Tan,J.Y., Luo,Y.L., Huang,X., Shao,J.L., Lin,L. and Yang,X.X.
TITLE [Association of single nucleotide polymorphisms of MD-1 gene with
asthma in adults of Han Nationality in Southern China]
JOURNAL Zhonghua Jie He He Hu Xi Za Zhi 34 (2), 104-108 (2011)
PUBMED 21426727
REMARK GeneRIF: MD-1 may be a disease susceptibility gene for adult asthma
in a Southern Han population in China.
REFERENCE 4 (bases 1 to 895)
AUTHORS Heid,I.M., Jackson,A.U., Randall,J.C., Winkler,T.W., Qi,L.,
Steinthorsdottir,V., Thorleifsson,G., Zillikens,M.C.,
Speliotes,E.K., Magi,R., Workalemahu,T., White,C.C.,
Bouatia-Naji,N., Harris,T.B., Berndt,S.I., Ingelsson,E.,
Willer,C.J., Weedon,M.N., Luan,J., Vedantam,S., Esko,T.,
Kilpelainen,T.O., Kutalik,Z., Li,S., Monda,K.L., Dixon,A.L.,
Holmes,C.C., Kaplan,L.M., Liang,L., Min,J.L., Moffatt,M.F.,
Molony,C., Nicholson,G., Schadt,E.E., Zondervan,K.T., Feitosa,M.F.,
Ferreira,T., Lango Allen,H., Weyant,R.J., Wheeler,E., Wood,A.R.,
Estrada,K., Goddard,M.E., Lettre,G., Mangino,M., Nyholt,D.R.,
Purcell,S., Smith,A.V., Visscher,P.M., Yang,J., McCarroll,S.A.,
Nemesh,J., Voight,B.F., Absher,D., Amin,N., Aspelund,T., Coin,L.,
Glazer,N.L., Hayward,C., Heard-Costa,N.L., Hottenga,J.J.,
Johansson,A., Johnson,T., Kaakinen,M., Kapur,K., Ketkar,S.,
Knowles,J.W., Kraft,P., Kraja,A.T., Lamina,C., Leitzmann,M.F.,
McKnight,B., Morris,A.P., Ong,K.K., Perry,J.R., Peters,M.J.,
Polasek,O., Prokopenko,I., Rayner,N.W., Ripatti,S., Rivadeneira,F.,
Robertson,N.R., Sanna,S., Sovio,U., Surakka,I., Teumer,A., van
Wingerden,S., Vitart,V., Zhao,J.H., Cavalcanti-Proenca,C.,
Chines,P.S., Fisher,E., Kulzer,J.R., Lecoeur,C., Narisu,N.,
Sandholt,C., Scott,L.J., Silander,K., Stark,K., Tammesoo,M.L.,
Teslovich,T.M., Timpson,N.J., Watanabe,R.M., Welch,R.,
Chasman,D.I., Cooper,M.N., Jansson,J.O., Kettunen,J.,
Lawrence,R.W., Pellikka,N., Perola,M., Vandenput,L., Alavere,H.,
Almgren,P., Atwood,L.D., Bennett,A.J., Biffar,R., Bonnycastle,L.L.,
Bornstein,S.R., Buchanan,T.A., Campbell,H., Day,I.N., Dei,M.,
Dorr,M., Elliott,P., Erdos,M.R., Eriksson,J.G., Freimer,N.B.,
Fu,M., Gaget,S., Geus,E.J., Gjesing,A.P., Grallert,H., Grassler,J.,
Groves,C.J., Guiducci,C., Hartikainen,A.L., Hassanali,N.,
Havulinna,A.S., Herzig,K.H., Hicks,A.A., Hui,J., Igl,W.,
Jousilahti,P., Jula,A., Kajantie,E., Kinnunen,L., Kolcic,I.,
Koskinen,S., Kovacs,P., Kroemer,H.K., Krzelj,V., Kuusisto,J.,
Kvaloy,K., Laitinen,J., Lantieri,O., Lathrop,G.M., Lokki,M.L.,
Luben,R.N., Ludwig,B., McArdle,W.L., McCarthy,A., Morken,M.A.,
Nelis,M., Neville,M.J., Pare,G., Parker,A.N., Peden,J.F.,
Pichler,I., Pietilainen,K.H., Platou,C.G., Pouta,A.,
Ridderstrale,M., Samani,N.J., Saramies,J., Sinisalo,J., Smit,J.H.,
Strawbridge,R.J., Stringham,H.M., Swift,A.J., Teder-Laving,M.,
Thomson,B., Usala,G., van Meurs,J.B., van Ommen,G.J., Vatin,V.,
Volpato,C.B., Wallaschofski,H., Walters,G.B., Widen,E., Wild,S.H.,
Willemsen,G., Witte,D.R., Zgaga,L., Zitting,P., Beilby,J.P.,
James,A.L., Kahonen,M., Lehtimaki,T., Nieminen,M.S., Ohlsson,C.,
Palmer,L.J., Raitakari,O., Ridker,P.M., Stumvoll,M., Tonjes,A.,
Viikari,J., Balkau,B., Ben-Shlomo,Y., Bergman,R.N., Boeing,H.,
Smith,G.D., Ebrahim,S., Froguel,P., Hansen,T., Hengstenberg,C.,
Hveem,K., Isomaa,B., Jorgensen,T., Karpe,F., Khaw,K.T., Laakso,M.,
Lawlor,D.A., Marre,M., Meitinger,T., Metspalu,A., Midthjell,K.,
Pedersen,O., Salomaa,V., Schwarz,P.E., Tuomi,T., Tuomilehto,J.,
Valle,T.T., Wareham,N.J., Arnold,A.M., Beckmann,J.S., Bergmann,S.,
Boerwinkle,E., Boomsma,D.I., Caulfield,M.J., Collins,F.S.,
Eiriksdottir,G., Gudnason,V., Gyllensten,U., Hamsten,A.,
Hattersley,A.T., Hofman,A., Hu,F.B., Illig,T., Iribarren,C.,
Jarvelin,M.R., Kao,W.H., Kaprio,J., Launer,L.J., Munroe,P.B.,
Oostra,B., Penninx,B.W., Pramstaller,P.P., Psaty,B.M.,
Quertermous,T., Rissanen,A., Rudan,I., Shuldiner,A.R., Soranzo,N.,
Spector,T.D., Syvanen,A.C., Uda,M., Uitterlinden,A., Volzke,H.,
Vollenweider,P., Wilson,J.F., Witteman,J.C., Wright,A.F.,
Abecasis,G.R., Boehnke,M., Borecki,I.B., Deloukas,P.,
Frayling,T.M., Groop,L.C., Haritunians,T., Hunter,D.J.,
Kaplan,R.C., North,K.E., O'Connell,J.R., Peltonen,L.,
Schlessinger,D., Strachan,D.P., Hirschhorn,J.N., Assimes,T.L.,
Wichmann,H.E., Thorsteinsdottir,U., van Duijn,C.M., Stefansson,K.,
Cupples,L.A., Loos,R.J., Barroso,I., McCarthy,M.I., Fox,C.S.,
Mohlke,K.L. and Lindgren,C.M.
CONSRTM MAGIC
TITLE Meta-analysis identifies 13 new loci associated with waist-hip
ratio and reveals sexual dimorphism in the genetic basis of fat
distribution
JOURNAL Nat. Genet. 42 (11), 949-960 (2010)
PUBMED 20935629
REMARK GeneRIF: Observational study and genome-wide association study of
gene-disease association. (HuGE Navigator)
Erratum:[Nat Genet. 2011 Nov;43(11):1164]
REFERENCE 5 (bases 1 to 895)
AUTHORS Davila,S., Froeling,F.E., Tan,A., Bonnard,C., Boland,G.J.,
Snippe,H., Hibberd,M.L. and Seielstad,M.
TITLE New genetic associations detected in a host response study to
hepatitis B vaccine
JOURNAL Genes Immun. 11 (3), 232-238 (2010)
PUBMED 20237496
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 6 (bases 1 to 895)
AUTHORS Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
Dunham,I., Rogers,J. and Beck,S.
TITLE The DNA sequence and analysis of human chromosome 6
JOURNAL Nature 425 (6960), 805-811 (2003)
PUBMED 14574404
REFERENCE 7 (bases 1 to 895)
AUTHORS Ogata,H., Su,I., Miyake,K., Nagai,Y., Akashi,S., Mecklenbrauker,I.,
Rajewsky,K., Kimoto,M. and Tarakhovsky,A.
TITLE The toll-like receptor protein RP105 regulates lipopolysaccharide
signaling in B cells
JOURNAL J. Exp. Med. 192 (1), 23-29 (2000)
PUBMED 10880523
REFERENCE 8 (bases 1 to 895)
AUTHORS Begum,N.A., Tsuji,S., Nomura,M., Shida,K., Azuma,I., Hayashi,A.,
Matsumoto,M., Seya,T. and Toyoshima,K.
TITLE Human MD-1 homologue is a BCG-regulated gene product in monocytes:
its identification by differential display
JOURNAL Biochem. Biophys. Res. Commun. 256 (2), 325-329 (1999)
PUBMED 10079183
REFERENCE 9 (bases 1 to 895)
AUTHORS Miura,Y., Shimazu,R., Miyake,K., Akashi,S., Ogata,H., Yamashita,Y.,
Narisawa,Y. and Kimoto,M.
TITLE RP105 is associated with MD-1 and transmits an activation signal in
human B cells
JOURNAL Blood 92 (8), 2815-2822 (1998)
PUBMED 9763566
REFERENCE 10 (bases 1 to 895)
AUTHORS Miyake,K., Shimazu,R., Kondo,J., Niki,T., Akashi,S., Ogata,H.,
Yamashita,Y., Miura,Y. and Kimoto,M.
TITLE Mouse MD-1, a molecule that is physically associated with RP105 and
positively regulates its expression
JOURNAL J. Immunol. 161 (3), 1348-1353 (1998)
PUBMED 9686597
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
CD695164.1 and BC038846.1.
On Nov 16, 2004 this sequence version replaced gi:52856401.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC038846.1, AF057178.2 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025084, ERS025088 [ECO:0000348]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-527 CD695164.1 65-591
528-895 BC038846.1 538-905
FEATURES Location/Qualifiers
source 1..895
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="6"
/map="6p25.1"
gene 1..895
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/note="lymphocyte antigen 86"
/db_xref="GeneID:9450"
/db_xref="HGNC:16837"
/db_xref="HPRD:05578"
/db_xref="MIM:605241"
exon 1..170
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/inference="alignment:Splign:1.39.8"
variation 3
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="a"
/replace="g"
/db_xref="dbSNP:376619727"
variation 31
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="c"
/replace="t"
/db_xref="dbSNP:141209631"
variation 33
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="c"
/replace="t"
/db_xref="dbSNP:142081955"
CDS 35..523
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/note="MD-1, RP105-associated; ly-86; protein MD-1"
/codon_start=1
/product="lymphocyte antigen 86 precursor"
/protein_id="NP_004262.1"
/db_xref="GI:4758708"
/db_xref="CCDS:CCDS4498.1"
/db_xref="GeneID:9450"
/db_xref="HGNC:16837"
/db_xref="HPRD:05578"
/db_xref="MIM:605241"
/translation="
MKGFTATLFLWTLIFPSCSGGGGGKAWPTHVVCSDSGLEVLYQSCDPLQDFGFSVEKCSKQLKSNINIRFGIILREDIKELFLDLALMSQGSSVLNFSYPICEAALPKFSFCGRRKGEQIYYAGPVNNPEFTIPQGEYQVLLELYTEKRSTVACANATIMCS
"
sig_peptide 35..94
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/inference="COORDINATES: ab initio prediction:SignalP:4.0"
mat_peptide 95..520
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/product="Lymphocyte antigen 86"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (O95711.1)"
misc_feature 122..511
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/note="MD-1 and MD-2 are cofactors required for LPS
signaling through cell surface receptors. MD-2 and its
binding partner, Toll-like receptor 4 (TLR4), are
essential for the innate immune responses of mammalian
cells to bacterial lipopolysaccharide (LPS); MD-2...;
Region: MD-1_MD-2; cd00915"
/db_xref="CDD:29926"
misc_feature order(122..124,146..148,152..154,158..160,212..214,
230..232,236..238,242..244,281..283,287..289,293..295,
335..337,374..376,398..400,449..451,455..457,461..463,
467..469,488..490,497..499,503..505,509..511)
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/note="putative lipid binding cavity [chemical binding];
other site"
/db_xref="CDD:29926"
variation 40
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="c"
/replace="g"
/db_xref="dbSNP:369059581"
variation 47..48
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace=""
/replace="cccc"
/replace="ccccc"
/db_xref="dbSNP:145808577"
variation 47
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="a"
/replace="c"
/db_xref="dbSNP:78057476"
variation 64
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="c"
/replace="t"
/db_xref="dbSNP:74356155"
variation 100
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="c"
/replace="t"
/db_xref="dbSNP:139269722"
variation 101
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="a"
/replace="g"
/db_xref="dbSNP:376603538"
variation 107
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="a"
/replace="g"
/db_xref="dbSNP:75006006"
variation 109
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="a"
/replace="g"
/db_xref="dbSNP:149989688"
variation 111
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370576233"
variation 136
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="c"
/replace="t"
/db_xref="dbSNP:144373281"
variation 137
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="c"
/replace="g"
/db_xref="dbSNP:377638373"
variation 156
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="c"
/replace="t"
/db_xref="dbSNP:199618297"
variation 162
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="a"
/replace="g"
/db_xref="dbSNP:374594594"
variation 169
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201912095"
exon 171..257
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/inference="alignment:Splign:1.39.8"
variation 197
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148799324"
variation 200..201
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace=""
/replace="a"
/db_xref="dbSNP:34247656"
variation 208
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="a"
/replace="t"
/db_xref="dbSNP:201924366"
variation 249
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="g"
/replace="t"
/db_xref="dbSNP:142377958"
variation 252
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="g"
/replace="t"
/db_xref="dbSNP:200582242"
exon 258..386
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/inference="alignment:Splign:1.39.8"
variation 311
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="c"
/replace="t"
/db_xref="dbSNP:5743649"
variation 331
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="a"
/replace="t"
/db_xref="dbSNP:371613117"
exon 387..439
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/inference="alignment:Splign:1.39.8"
variation 396
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="a"
/replace="g"
/db_xref="dbSNP:5743651"
variation 399
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="a"
/replace="g"
/db_xref="dbSNP:144342238"
variation 400
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="c"
/replace="t"
/db_xref="dbSNP:147765605"
variation 428
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="a"
/replace="g"
/db_xref="dbSNP:146986566"
variation 434
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="c"
/replace="t"
/db_xref="dbSNP:140062866"
exon 440..879
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/inference="alignment:Splign:1.39.8"
variation 480
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="a"
/replace="g"
/db_xref="dbSNP:76751952"
variation 481
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="a"
/replace="g"
/db_xref="dbSNP:185732402"
variation 493
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="c"
/replace="t"
/db_xref="dbSNP:377039830"
STS 499..869
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/standard_name="LY86__7346"
/db_xref="UniSTS:466288"
variation 512
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="a"
/replace="g"
/db_xref="dbSNP:1802323"
variation 519
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="c"
/replace="g"
/db_xref="dbSNP:371434032"
variation 537
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="g"
/replace="t"
/db_xref="dbSNP:201979655"
variation 561
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="c"
/replace="t"
/db_xref="dbSNP:190409396"
variation 562
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="a"
/replace="g"
/db_xref="dbSNP:2233128"
variation 565
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="a"
/replace="g"
/db_xref="dbSNP:112322999"
STS 714..840
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/standard_name="SHGC-33709"
/db_xref="UniSTS:12891"
variation 793
/gene="LY86"
/gene_synonym="dJ80N2.1; MD-1; MMD-1; RP1-80N2.1"
/replace="g"
/replace="t"
/db_xref="dbSNP:116693754"
ORIGIN
ttatttttctgtgtgtcccatacaggcccccaccatgaagggtttcacagccactctcttcctctggactctgatttttcccagctgcagtggaggcggcggtgggaaagcctggcccacacacgtggtctgtagcgacagcggcttggaagtgctctaccagagttgcgatccattacaagattttggcttttctgttgaaaagtgttccaagcaattaaaatcaaatatcaacattagatttggaattattctgagagaggacatcaaagagctttttcttgacctagctctcatgtctcaaggctcatctgttttgaatttctcctatcccatctgtgaggcggctctgcccaagttttctttctgtggaagaaggaaaggagagcagatttactatgctgggcctgtcaataatcctgaatttactattcctcagggagaataccaggttttgctggaactgtacactgaaaaacggtccaccgtggcctgtgccaatgctactatcatgtgctcctgactgtggcctgtagcaaaaatcacagccagctgcatctcgtgggacctccaagctcctctgactgaacctactgtgggaggagaagcagctgatgacagagagaggctctacaaagaagcgcccccaaagagtgcagctgctaattttagtcccaggaccagacatccccagactccacagatgtaatgaagtccccgaatgtatctgtttctaaggagcctcttggcagtccttaagcagtcttgagggtccatcctttttctctaattggtcgcctcccaccagactcacctgcttttcaactttttaggagtgcttcctcacagttaccaagaataaagaaagctggccaccataaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:9450 -> Biological process: GO:0006915 [apoptotic process] evidence: TAS
GeneID:9450 -> Biological process: GO:0006954 [inflammatory response] evidence: IEA
GeneID:9450 -> Biological process: GO:0006959 [humoral immune response] evidence: TAS
GeneID:9450 -> Biological process: GO:0008283 [cell proliferation] evidence: TAS
GeneID:9450 -> Biological process: GO:0031666 [positive regulation of lipopolysaccharide-mediated signaling pathway] evidence: IGI
GeneID:9450 -> Biological process: GO:0045087 [innate immune response] evidence: IEA
GeneID:9450 -> Cellular component: GO:0005615 [extracellular space] evidence: IEA
GeneID:9450 -> Cellular component: GO:0005886 [plasma membrane] evidence: TAS
by
@meso_cacase at
DBCLS
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