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2024-04-19 23:54:54, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_003998 4093 bp mRNA linear PRI 15-JUL-2013
DEFINITION Homo sapiens nuclear factor of kappa light polypeptide gene
enhancer in B-cells 1 (NFKB1), transcript variant 1, mRNA.
ACCESSION NM_003998
VERSION NM_003998.3 GI:259155300
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4093)
AUTHORS Starokadomskyy,P., Gluck,N., Li,H., Chen,B., Wallis,M., Maine,G.N.,
Mao,X., Zaidi,I.W., Hein,M.Y., McDonald,F.J., Lenzner,S., Zecha,A.,
Ropers,H.H., Kuss,A.W., McGaughran,J., Gecz,J. and Burstein,E.
TITLE CCDC22 deficiency in humans blunts activation of proinflammatory
NF-kappaB signaling
JOURNAL J. Clin. Invest. 123 (5), 2244-2256 (2013)
PUBMED 23563313
REMARK GeneRIF: CCDC22 participates in NF-kappaB activation and its
deficiency leads to decreased IkappaB turnover
REFERENCE 2 (bases 1 to 4093)
AUTHORS Loganathan,R., Selvaduray,K.R., Nesaretnam,K. and
Radhakrishnan,A.K.
TITLE Tocotrienols promote apoptosis in human breast cancer cells by
inducing poly(ADP-ribose) polymerase cleavage and inhibiting
nuclear factor kappa-B activity
JOURNAL Cell Prolif. 46 (2), 203-213 (2013)
PUBMED 23510475
REMARK GeneRIF: Tocotrienols inhibited expression of nuclear factor
kappa-B, which in turn can increase sensitivity of cancer cells to
apoptosis.
REFERENCE 3 (bases 1 to 4093)
AUTHORS Zhang,L., Alter,H.J., Wang,H., Jia,S., Wang,E., Marincola,F.M.,
Shih,J.W. and Wang,R.Y.
TITLE The modulation of hepatitis C virus 1a replication by PKR is
dependent on NF-kB mediated interferon beta response in Huh7.5.1
cells
JOURNAL Virology 438 (1), 28-36 (2013)
PUBMED 23399035
REMARK GeneRIF: Authors conclude that host cells can employ PKR activation
to restrict hepatitis C virus 1a replication through regulation of
NF-kB expression.
REFERENCE 4 (bases 1 to 4093)
AUTHORS Li,Q., Syrovets,T., Simmet,T., Ding,J., Xu,J., Chen,W., Zhu,D. and
Gao,P.
TITLE Plasmin induces intercellular adhesion molecule 1 expression in
human endothelial cells via nuclear factor-kappaB/mitogen-activated
protein kinases-dependent pathways
JOURNAL Exp. Biol. Med. (Maywood) 238 (2), 176-186 (2013)
PUBMED 23576799
REMARK GeneRIF: Further, plasmin stimulates the NF-kappaB/p38-dependent
expression of ICAM-1 by human umbilical vein endothelial cells.
REFERENCE 5 (bases 1 to 4093)
AUTHORS Bolati,D., Shimizu,H., Yisireyili,M., Nishijima,F. and Niwa,T.
TITLE Indoxyl sulfate, a uremic toxin, downregulates renal expression of
Nrf2 through activation of NF-kappaB
JOURNAL BMC Nephrol 14, 56 (2013)
PUBMED 23496811
REMARK GeneRIF: renal expression of 8-OHdG compared with control CKD rats.
CONCLUSIONS: Indoxyl sulfate downregulates renal expression of Nrf2
through activation of NF-kappaB, followed by downregulation of HO-1
and NQO1 and increased production of ROS.
Publication Status: Online-Only
REFERENCE 6 (bases 1 to 4093)
AUTHORS LeClair,K.P., Blanar,M.A. and Sharp,P.A.
TITLE The p50 subunit of NF-kappa B associates with the NF-IL6
transcription factor
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 89 (17), 8145-8149 (1992)
PUBMED 1518839
REFERENCE 7 (bases 1 to 4093)
AUTHORS Taylor,J.P., Pomerantz,R., Bagasra,O., Chowdhury,M., Rappaport,J.,
Khalili,K. and Amini,S.
TITLE TAR-independent transactivation by Tat in cells derived from the
CNS: a novel mechanism of HIV-1 gene regulation
JOURNAL EMBO J. 11 (9), 3395-3403 (1992)
PUBMED 1505523
REFERENCE 8 (bases 1 to 4093)
AUTHORS Liptay,S., Schmid,R.M., Perkins,N.D., Meltzer,P., Altherr,M.R.,
McPherson,J.D., Wasmuth,J.J. and Nabel,G.J.
TITLE Related subunits of NF-kappa B map to two distinct loci associated
with translocations in leukemia, NFKB1 and NFKB2
JOURNAL Genomics 13 (2), 287-292 (1992)
PUBMED 1612589
REFERENCE 9 (bases 1 to 4093)
AUTHORS Liu,J., Perkins,N.D., Schmid,R.M. and Nabel,G.J.
TITLE Specific NF-kappa B subunits act in concert with Tat to stimulate
human immunodeficiency virus type 1 transcription
JOURNAL J. Virol. 66 (6), 3883-3887 (1992)
PUBMED 1583734
REFERENCE 10 (bases 1 to 4093)
AUTHORS Meyer,R., Hatada,E.N., Hohmann,H.P., Haiker,M., Bartsch,C.,
Rothlisberger,U., Lahm,H.W., Schlaeger,E.J., van Loon,A.P. and
Scheidereit,C.
TITLE Cloning of the DNA-binding subunit of human nuclear factor kappa B:
the level of its mRNA is strongly regulated by phorbol ester or
tumor necrosis factor alpha
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 88 (3), 966-970 (1991)
PUBMED 1992489
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BC051765.1, AF213884.2 and
AI076882.1.
On Sep 24, 2009 this sequence version replaced gi:34577121.
Summary: This gene encodes a 105 kD protein which can undergo
cotranslational processing by the 26S proteasome to produce a 50 kD
protein. The 105 kD protein is a Rel protein-specific transcription
inhibitor and the 50 kD protein is a DNA binding subunit of the
NF-kappa-B (NFKB) protein complex. NFKB is a transcription
regulator that is activated by various intra- and extra-cellular
stimuli such as cytokines, oxidant-free radicals, ultraviolet
irradiation, and bacterial or viral products. Activated NFKB
translocates into the nucleus and stimulates the expression of
genes involved in a wide variety of biological functions.
Inappropriate activation of NFKB has been associated with a number
of inflammatory diseases while persistent inhibition of NFKB leads
to inappropriate immune cell development or delayed cell growth.
Two transcript variants encoding different isoforms have been found
for this gene. [provided by RefSeq, Sep 2009].
Transcript Variant: This variant (1) represents the longer
transcript and encodes the longer isoform (1).
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC051765.1, M55643.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025083, ERS025084 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-1609 BC051765.1 1-1609
1610-1610 AF213884.2 158245-158245
1611-3896 BC051765.1 1611-3896
3897-4093 AI076882.1 1-197 c
FEATURES Location/Qualifiers
source 1..4093
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="4"
/map="4q24"
gene 1..4093
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/note="nuclear factor of kappa light polypeptide gene
enhancer in B-cells 1"
/db_xref="GeneID:4790"
/db_xref="HGNC:7794"
/db_xref="MIM:164011"
exon 1..460
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 19
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="g"
/db_xref="dbSNP:72696119"
variation 28..29
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:11556613"
misc_feature 408..410
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/note="upstream in-frame stop codon"
exon 461..506
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
CDS 468..3377
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/note="isoform 1 is encoded by transcript variant 1;
NF-kappabeta; nuclear factor kappa-B DNA binding subunit;
nuclear factor NF-kappa-B p50 subunit; DNA binding factor
KBF1; nuclear factor NF-kappa-B p105 subunit; DNA-binding
factor KBF1"
/codon_start=1
/product="nuclear factor NF-kappa-B p105 subunit isoform
1"
/protein_id="NP_003989.2"
/db_xref="GI:34577122"
/db_xref="CCDS:CCDS3657.1"
/db_xref="GeneID:4790"
/db_xref="HGNC:7794"
/db_xref="MIM:164011"
/translation="
MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTADGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCEDGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQAEGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITFHPGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNGEVTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVEDLLRAGADLSLLDRLGNSVLHLAAKEGHDKVLSILLKHKKAALLLDHPNGDGLNAIHLAMMSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMATSWQVFDILNGKPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTSQAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYGQEGPLEGKI
"
misc_feature 594..1199
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/note="N-terminal sub-domain of the Rel homology domain
(RHD) of nuclear factor of kappa B1 (NF-kappa B1); Region:
RHD-n_NFkB1; cd07935"
/db_xref="CDD:143651"
misc_feature order(636..638,642..647,651..656,663..674,897..899,
903..908,1197..1199)
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:143651"
misc_feature 651..653
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="S-nitrosocysteine, alternate; propagated from
UniProtKB/Swiss-Prot (P19838.2); nitrosylation site"
misc_feature 1218..1523
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/note="IPT domain of the transcription factor NFkappaB and
related transcription factors. NFkappaB is considered a
central regulator of stress responses, activated by
different stressful conditions, including physical stress,
oxidative stress, and exposure to...; Region:
IPT_NFkappaB; cd01177"
/db_xref="CDD:28992"
misc_feature order(1221..1223,1227..1235,1239..1247,1365..1373,
1410..1412,1446..1448,1503..1505,1512..1514,1518..1520)
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/note="ankyrin protein binding site [polypeptide binding];
other site"
/db_xref="CDD:28992"
misc_feature order(1227..1232,1236..1238,1275..1277,1281..1283,
1287..1289,1386..1391,1398..1400,1404..1406)
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:28992"
misc_feature order(1290..1292,1296..1298,1389..1394)
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:28992"
misc_feature 1479..1481
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:03382"
misc_feature 1548..1565
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (P19838.2);
Region: Nuclear localization signal (Potential)"
misc_feature 1584..1652
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P19838.2);
Region: GRR"
misc_feature 1767..1772
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="Cleavage (when cotranslationally processed);
propagated from UniProtKB/Swiss-Prot (P19838.2); cleavage
site"
misc_feature 1773..3374
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P19838.2);
Region: Interaction with CFLAR"
misc_feature 2028..2306
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/note="Ankyrin repeats (3 copies); Region: Ank_2;
pfam12796"
/db_xref="CDD:205076"
misc_feature 2196..2684
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/note="ankyrin repeats; ankyrin repeats mediate
protein-protein interactions in very diverse families of
proteins. The number of ANK repeats in a protein can range
from 2 to over 20 (ankyrins, for example). ANK repeats may
occur in combinations with other...; Region: ANK; cd00204"
/db_xref="CDD:29261"
misc_feature 2226..2510
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/note="Ankyrin repeats (3 copies); Region: Ank_2;
pfam12796"
/db_xref="CDD:205076"
misc_feature 2418..2522
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P19838.2);
Region: Essential for interaction with HIF1AN"
misc_feature 2433..2717
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/note="Ankyrin repeats (3 copies); Region: Ank_2;
pfam12796"
/db_xref="CDD:205076"
misc_feature 2502..2504
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="(3S)-3-hydroxyasparagine, by HIF1AN, partial;
propagated from UniProtKB/Swiss-Prot (P19838.2);
hydroxylation site"
misc_feature 2913..3140
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/note="Death domain of the Nuclear Factor-KappaB1
precursor protein p105; Region: Death_NFkB1_p105; cd08797"
/db_xref="CDD:176775"
misc_feature 3147..3149
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3165..3167
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:05418"
misc_feature 3177..3179
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by GSK3-beta, in vitro; propagated
from UniProtKB/Swiss-Prot (P19838.2); phosphorylation
site"
misc_feature 3177..3179
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:05418"
misc_feature 3189..3191
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by GSK3-beta, in vitro; propagated
from UniProtKB/Swiss-Prot (P19838.2); phosphorylation
site"
misc_feature 3189..3191
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:05418"
misc_feature 3231..3233
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:02811"
misc_feature 3237..3239
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:02811"
misc_feature 3237..3239
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:04462"
misc_feature 3249..3251
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by IKKB; propagated from
UniProtKB/Swiss-Prot (P19838.2); phosphorylation site"
misc_feature 3249..3251
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:04462"
misc_feature 3249..3251
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:02811"
misc_feature 3261..3263
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:02811"
misc_feature 3264..3266
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by IKKB; propagated from
UniProtKB/Swiss-Prot (P19838.2); phosphorylation site"
misc_feature 3264..3266
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:02811"
misc_feature 3279..3281
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(P19838.2); phosphorylation site"
exon 507..585
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 526
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="g"
/db_xref="dbSNP:370685242"
exon 586..626
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 594
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="g"
/db_xref="dbSNP:201487209"
exon 627..725
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 686
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:4648003"
exon 726..874
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 752
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:139566935"
variation 809
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="g"
/db_xref="dbSNP:371466957"
variation 869
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:149703243"
variation 873
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:199574943"
exon 875..1038
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 878
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:369582218"
variation 950
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:373249652"
variation 960
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:376562815"
variation 995
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:142991798"
variation 1017
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:370312017"
variation 1027
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:201874528"
exon 1039..1197
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 1059
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:370846760"
variation 1075
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="t"
/db_xref="dbSNP:112424808"
variation 1079
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:374621663"
variation 1115
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:200893106"
variation 1159
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="g"
/replace="t"
/db_xref="dbSNP:146936581"
variation 1182
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:200186183"
exon 1198..1302
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 1265
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:376678247"
variation 1301
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:200630550"
exon 1303..1394
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
exon 1395..1533
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 1418
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:373322154"
variation 1421
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:147558315"
variation 1445
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="c"
/db_xref="dbSNP:201065307"
variation 1451
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="g"
/db_xref="dbSNP:149014458"
variation 1471
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:143817570"
variation 1496
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:377158171"
variation 1499
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:370636374"
variation 1517
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:4648039"
exon 1534..1677
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 1582
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:371719137"
variation 1592
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:141951153"
variation 1593
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:150233754"
variation 1610
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:1609993"
variation 1613
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:142008564"
variation 1620
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:376020000"
variation 1643..1644
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace=""
/replace="ggggggggggggggg"
/db_xref="dbSNP:144869243"
variation 1653
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:201183726"
exon 1678..1767
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 1713
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:369442929"
variation 1748
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:146311906"
exon 1768..1962
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 1771
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="c"
/db_xref="dbSNP:56280473"
variation 1794
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="g"
/replace="t"
/db_xref="dbSNP:183929764"
variation 1799
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:139489039"
variation 1804
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:149548281"
variation 1809
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:202196813"
variation 1855
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:144132174"
variation 1873
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:113440082"
variation 1883
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:371483323"
variation 1891
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="g"
/db_xref="dbSNP:201777128"
variation 1894
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:368857298"
variation 1896
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:56147914"
variation 1906
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="g"
/replace="t"
/db_xref="dbSNP:370612125"
variation 1910
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:372604755"
variation 1934
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:41354247"
variation 1936
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:4648065"
variation 1947
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="c"
/db_xref="dbSNP:376402199"
variation 1951
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:370018067"
exon 1963..2104
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 1967
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="c"
/db_xref="dbSNP:201395077"
variation 1980
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="c"
/db_xref="dbSNP:370232532"
variation 1986
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:4648072"
variation 2036
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:374982272"
variation 2060
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:200448331"
variation 2061
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:139575566"
variation 2068
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:150281816"
exon 2105..2219
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 2121
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:147574894"
variation 2141
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:371986555"
variation 2167
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:4648085"
variation 2177
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="g"
/replace="t"
/db_xref="dbSNP:200626732"
variation 2203
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:4648086"
variation 2210
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:190121351"
exon 2220..2421
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 2222
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:4648093"
variation 2266
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="c"
/db_xref="dbSNP:55661548"
variation 2289
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="g"
/db_xref="dbSNP:11556612"
variation 2298
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:144066812"
variation 2307
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:374903458"
variation 2312
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="g"
/replace="t"
/db_xref="dbSNP:149211506"
variation 2315
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:371289131"
variation 2331
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="g"
/db_xref="dbSNP:201559647"
variation 2336
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="g"
/replace="t"
/db_xref="dbSNP:4648094"
variation 2366
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:145118935"
variation 2381
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:138948343"
variation 2393
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="t"
/db_xref="dbSNP:61751049"
variation 2414..2415
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace=""
/replace="g"
/db_xref="dbSNP:35040256"
variation 2415
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:375088091"
exon 2422..2591
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 2430
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:113549494"
variation 2459
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:141773343"
variation 2527
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:148097278"
variation 2555
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:374233606"
variation 2571
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:111293796"
variation 2578
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="g"
/replace="t"
/db_xref="dbSNP:141844350"
variation 2588
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:184070765"
exon 2592..2694
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 2603
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="g"
/replace="t"
/db_xref="dbSNP:4648099"
variation 2612
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="g"
/replace="t"
/db_xref="dbSNP:376030164"
variation 2654
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:200845765"
variation 2668
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="g"
/replace="t"
/db_xref="dbSNP:370433110"
exon 2695..2819
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 2699
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:138657975"
variation 2740
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:368017285"
variation 2803
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:369716580"
exon 2820..2886
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 2845
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="g"
/db_xref="dbSNP:201233299"
variation 2873
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="g"
/replace="t"
/db_xref="dbSNP:369593381"
exon 2887..3059
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 2904
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:149314909"
variation 2907
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:147412381"
variation 2915
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:370135976"
variation 2918
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="g"
/db_xref="dbSNP:139661580"
variation 2919
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:148212199"
variation 2927
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="g"
/db_xref="dbSNP:4648109"
variation 2977
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:373165003"
variation 2981
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:371153863"
variation 3016
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:374536762"
variation 3023
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="g"
/replace="t"
/db_xref="dbSNP:147169338"
variation 3024
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:376121386"
variation 3046
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:148626207"
exon 3060..3216
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 3075
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:372576307"
variation 3097
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:200451929"
variation 3104
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="c"
/db_xref="dbSNP:199668563"
variation 3116
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:369470181"
variation 3158
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:372519363"
variation 3170
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="g"
/db_xref="dbSNP:201708495"
variation 3171
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:4648118"
variation 3178
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:142074302"
variation 3179
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:4648119"
variation 3182
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="g"
/db_xref="dbSNP:1804009"
variation 3190
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:369577304"
variation 3196
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:372601198"
exon 3217..4085
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/inference="alignment:Splign:1.39.8"
variation 3218
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:151134704"
variation 3226
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:368962343"
variation 3233
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="g"
/replace="t"
/db_xref="dbSNP:41341444"
variation 3245
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:41452949"
variation 3248
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:111386727"
variation 3251
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:113109405"
variation 3270
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:200653734"
variation 3288
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:373316062"
variation 3298
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="c"
/db_xref="dbSNP:143882681"
variation 3337
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:201983448"
variation 3345
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:199909759"
variation 3347
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:201094030"
variation 3357
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:146862629"
variation 3358
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="c"
/db_xref="dbSNP:140660237"
STS 3379..3528
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/standard_name="NFKB1"
/db_xref="UniSTS:479868"
variation 3397
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:370726107"
STS 3398..3697
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/standard_name="SHGC-12798"
/db_xref="UniSTS:32542"
variation 3400
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:4648143"
variation 3480
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:192569750"
variation 3481
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:41275743"
variation 3485
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:184935116"
variation 3500
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="g"
/db_xref="dbSNP:146956339"
variation 3509
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="c"
/replace="t"
/db_xref="dbSNP:4648144"
variation 3628
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="g"
/replace="t"
/db_xref="dbSNP:4648145"
variation 3686
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:187500853"
variation 3763..3764
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace=""
/replace="t"
/db_xref="dbSNP:200448635"
variation 3764
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace=""
/replace="t"
/db_xref="dbSNP:4648146"
variation 3774
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="g"
/db_xref="dbSNP:191331408"
variation 3832
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace=""
/replace="a"
/db_xref="dbSNP:34022549"
variation 3832
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="t"
/db_xref="dbSNP:183913778"
variation 3881..3882
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace=""
/replace="a"
/replace="aa"
/replace="aaa"
/db_xref="dbSNP:5860728"
variation 3881
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace=""
/replace="c"
/db_xref="dbSNP:139517248"
variation 3885..3886
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace=""
/replace="ag"
/db_xref="dbSNP:368097103"
variation 3886..3887
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace=""
/replace="g"
/db_xref="dbSNP:201674260"
variation 3893..3894
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace=""
/replace="a"
/replace="aa"
/db_xref="dbSNP:34126565"
variation 3900..3901
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace=""
/replace="aaaa"
/db_xref="dbSNP:60869654"
variation 3902
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
/replace="a"
/replace="t"
/db_xref="dbSNP:368126261"
polyA_signal 4056..4061
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
polyA_site 4069
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
polyA_site 4072
/gene="NFKB1"
/gene_synonym="EBP-1; KBF1; NF-kappa-B; NF-kappaB; NF-kB1;
NFkappaB; NFKB-p105; NFKB-p50; p105; p50"
ORIGIN
gtgagagagtgagcgagacagaaagagagagaagtgcaccagcgagccggggcaggaagaggaggtttcgccaccggagcggcccggcgacgcgctgacagcttcccctgcccttcccgtcggtcgggccgccagccgccgcagccctcggcctgcacgcagccaccggccccgctcccggagcccagcgccgccgaggccgcagccgcccggccagtaaggcggcgccgccgcccggccaccgcgcgccctgcgcttccctccgcccgcgctgcggccatggcgcggcgctgactggcctggcccggccccgccgcgctcccgctcgccccgacccgcactcgggcccgcccgggctccggcctgccgccgcctcttccttctccagccggcaggcccgcgccgcttaggagggagagcccacccgcgccaggaggccgaacgcggactcgccacccggcttcagaatggcagaagatgatccatatttgggaaggcctgaacaaatgtttcatttggatccttctttgactcatacaatatttaatccagaagtatttcaaccacagatggcactgccaacagcagatggcccataccttcaaatattagagcaacctaaacagagaggatttcgtttccgttatgtatgtgaaggcccatcccatggtggactacctggtgcctctagtgaaaagaacaagaagtcttaccctcaggtcaaaatctgcaactatgtgggaccagcaaaggttattgttcagttggtcacaaatggaaaaaatatccacctgcatgcccacagcctggtgggaaaacactgtgaggatgggatctgcactgtaactgctggacccaaggacatggtggtcggcttcgcaaacctgggtatacttcatgtgacaaagaaaaaagtatttgaaacactggaagcacgaatgacagaggcgtgtataaggggctataatcctggactcttggtgcaccctgaccttgcctatttgcaagcagaaggtggaggggaccggcagctgggagatcgggaaaaagagctaatccgccaagcagctctgcagcagaccaaggagatggacctcagcgtggtgcggctcatgtttacagcttttcttccggatagcactggcagcttcacaaggcgcctggaacccgtggtatcagacgccatctatgacagtaaagcccccaatgcatccaacttgaaaattgtaagaatggacaggacagctggatgtgtgactggaggggaggaaatttatcttctttgtgacaaagttcagaaagatgacatccagattcgattttatgaagaggaagaaaatggtggagtctgggaaggatttggagatttttcccccacagatgttcatagacaatttgccattgtcttcaaaactccaaagtataaagatattaatattacaaaaccagcctctgtgtttgtccagcttcggaggaaatctgacttggaaactagtgaaccaaaacctttcctctactatcctgaaatcaaagataaagaagaagtgcagaggaaacgtcagaagctcatgcccaatttttcggatagtttcggcggtggtagtggtgctggagctggaggcggaggcatgtttggtagtggcggtggaggagggggcactggaagtacaggtccagggtatagcttcccacactatggatttcctacttatggtgggattactttccatcctggaactactaaatctaatgctgggatgaagcatggaaccatggacactgaatctaaaaaggaccctgaaggttgtgacaaaagtgatgacaaaaacactgtaaacctctttgggaaagttattgaaaccacagagcaagatcaggagcccagcgaggccaccgttgggaatggtgaggtcactctaacgtatgcaacaggaacaaaagaagagagtgctggagttcaggataacctctttctagagaaggctatgcagcttgcaaagaggcatgccaatgcccttttcgactacgcggtgacaggagacgtgaagatgctgctggccgtccagcgccatctcactgctgtgcaggatgagaatggggacagtgtcttacacttagcaatcatccaccttcattctcaacttgtgagggatctactagaagtcacatctggtttgatttctgatgacattatcaacatgagaaatgatctgtaccagacgcccttgcacttggcagtgatcactaagcaggaagatgtggtggaggatttgctgagggctggggccgacctgagccttctggaccgcttgggtaactctgttttgcacctagctgccaaagaaggacatgataaagttctcagtatcttactcaagcacaaaaaggcagcactacttcttgaccaccccaacggggacggtctgaatgccattcatctagccatgatgagcaatagcctgccatgtttgctgctgctggtggccgctggggctgacgtcaatgctcaggagcagaagtccgggcgcacagcactgcacctggctgtggagcacgacaacatctcattggcaggctgcctgctcctggagggtgatgcccatgtggacagtactacctacgatggaaccacacccctgcatatagcagctgggagagggtccaccaggctggcagctcttctcaaagcagcaggagcagatcccctggtggagaactttgagcctctctatgacctggatgactcttgggaaaatgcaggagaggatgaaggagttgtgcctggaaccacgcctctagatatggccaccagctggcaggtatttgacatattaaatgggaaaccatatgagccagagtttacatctgatgatttactagcacaaggagacatgaaacagctggctgaagatgtgaagctgcagctgtataagttactagaaattcctgatccagacaaaaactgggctactctggcgcagaaattaggtctggggatacttaataatgccttccggctgagtcctgctccttccaaaacacttatggacaactatgaggtctctgggggtacagtcagagagctggtggaggccctgagacaaatgggctacaccgaagcaattgaagtgatccaggcagcctccagcccagtgaagaccacctctcaggcccactcgctgcctctctcgcctgcctccacaaggcagcaaatagacgagctccgagacagtgacagtgtctgcgacagcggcgtggagacatccttccgcaaactcagctttaccgagtctctgaccagtggtgcctcactgctaactctcaacaaaatgccccatgattatgggcaggaaggacctctagaaggcaaaatttagcctgctgacaatttcccacaccgtgtaaaccaaagccctaaaattccactgcgttgtccacaagacagaagctgaagtgcatccaaaggtgctcagagagccggcccgcctgaatcattctcgatttaactcgagaccttttcaacttggcttcctttcttggttcataaatgaattttagtttggttcacttacagatagtatctagcaatcacaacactggctgagcggatgcatctggggatgaggttgcttactaagctttgccagctgctgctggatcacagctgctttctgttgtcattgctgttgtccctctgctacgttcctattgtcattaaaggtatcacggtcgccacctggcattccttctgaccacagcatcattttgcattcaaattaagggttaagaaaagagatattttaaaatgagagtcacttgatgtgccattttaaaaaaaaaggcatattgctttttctaatgtggttatttctctgatttgcaaaaaaaaaaaaaaaaaaaatacttgtcaatatttaaacatggttacaatcattgctgaaaatggtattttcccccttttctgcattttgctattgtaaatatgttttttagatcaaatactttaaaggaaaaaatgttggatttataaatgctattttttattttacttttataataaaaggaaaagcaaattgatgacctcaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:4790 -> Molecular function: GO:0000975 [regulatory region DNA binding] evidence: IDA
GeneID:4790 -> Molecular function: GO:0000976 [transcription regulatory region sequence-specific DNA binding] evidence: IDA
GeneID:4790 -> Molecular function: GO:0001071 [nucleic acid binding transcription factor activity] evidence: IDA
GeneID:4790 -> Molecular function: GO:0003690 [double-stranded DNA binding] evidence: IEA
GeneID:4790 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IEA
GeneID:4790 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:4790 -> Molecular function: GO:0008134 [transcription factor binding] evidence: IDA
GeneID:4790 -> Molecular function: GO:0031072 [heat shock protein binding] evidence: IEA
GeneID:4790 -> Molecular function: GO:0042803 [protein homodimerization activity] evidence: IEA
GeneID:4790 -> Molecular function: GO:0044212 [transcription regulatory region DNA binding] evidence: IDA
GeneID:4790 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IC
GeneID:4790 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IMP
GeneID:4790 -> Biological process: GO:0001818 [negative regulation of cytokine production] evidence: IEA
GeneID:4790 -> Biological process: GO:0002224 [toll-like receptor signaling pathway] evidence: TAS
GeneID:4790 -> Biological process: GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] evidence: TAS
GeneID:4790 -> Biological process: GO:0002756 [MyD88-independent toll-like receptor signaling pathway] evidence: TAS
GeneID:4790 -> Biological process: GO:0006366 [transcription from RNA polymerase II promoter] evidence: TAS
GeneID:4790 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:4790 -> Biological process: GO:0006954 [inflammatory response] evidence: TAS
GeneID:4790 -> Biological process: GO:0006979 [response to oxidative stress] evidence: IEA
GeneID:4790 -> Biological process: GO:0009617 [response to bacterium] evidence: IEA
GeneID:4790 -> Biological process: GO:0010744 [positive regulation of macrophage derived foam cell differentiation] evidence: IC
GeneID:4790 -> Biological process: GO:0010884 [positive regulation of lipid storage] evidence: IC
GeneID:4790 -> Biological process: GO:0010956 [negative regulation of calcidiol 1-monooxygenase activity] evidence: IDA
GeneID:4790 -> Biological process: GO:0010957 [negative regulation of vitamin D biosynthetic process] evidence: IC
GeneID:4790 -> Biological process: GO:0031293 [membrane protein intracellular domain proteolysis] evidence: TAS
GeneID:4790 -> Biological process: GO:0032269 [negative regulation of cellular protein metabolic process] evidence: IC
GeneID:4790 -> Biological process: GO:0032375 [negative regulation of cholesterol transport] evidence: IC
GeneID:4790 -> Biological process: GO:0032481 [positive regulation of type I interferon production] evidence: TAS
GeneID:4790 -> Biological process: GO:0034134 [toll-like receptor 2 signaling pathway] evidence: TAS
GeneID:4790 -> Biological process: GO:0034138 [toll-like receptor 3 signaling pathway] evidence: TAS
GeneID:4790 -> Biological process: GO:0034142 [toll-like receptor 4 signaling pathway] evidence: TAS
GeneID:4790 -> Biological process: GO:0034146 [toll-like receptor 5 signaling pathway] evidence: TAS
GeneID:4790 -> Biological process: GO:0034162 [toll-like receptor 9 signaling pathway] evidence: TAS
GeneID:4790 -> Biological process: GO:0034166 [toll-like receptor 10 signaling pathway] evidence: TAS
GeneID:4790 -> Biological process: GO:0035666 [TRIF-dependent toll-like receptor signaling pathway] evidence: TAS
GeneID:4790 -> Biological process: GO:0038095 [Fc-epsilon receptor signaling pathway] evidence: TAS
GeneID:4790 -> Biological process: GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] evidence: TAS
GeneID:4790 -> Biological process: GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] evidence: TAS
GeneID:4790 -> Biological process: GO:0043066 [negative regulation of apoptotic process] evidence: TAS
GeneID:4790 -> Biological process: GO:0045083 [negative regulation of interleukin-12 biosynthetic process] evidence: IEA
GeneID:4790 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
GeneID:4790 -> Biological process: GO:0045893 [positive regulation of transcription, DNA-dependent] evidence: IDA
GeneID:4790 -> Biological process: GO:0045893 [positive regulation of transcription, DNA-dependent] evidence: IMP
GeneID:4790 -> Biological process: GO:0045893 [positive regulation of transcription, DNA-dependent] evidence: NAS
GeneID:4790 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IEA
GeneID:4790 -> Biological process: GO:0046688 [response to copper ion] evidence: IEA
GeneID:4790 -> Biological process: GO:0048011 [neurotrophin TRK receptor signaling pathway] evidence: TAS
GeneID:4790 -> Biological process: GO:0050728 [negative regulation of inflammatory response] evidence: IEA
GeneID:4790 -> Biological process: GO:0050852 [T cell receptor signaling pathway] evidence: TAS
GeneID:4790 -> Biological process: GO:0051092 [positive regulation of NF-kappaB transcription factor activity] evidence: TAS
GeneID:4790 -> Biological process: GO:0071260 [cellular response to mechanical stimulus] evidence: IEP
GeneID:4790 -> Biological process: GO:0071347 [cellular response to interleukin-1] evidence: IEP
GeneID:4790 -> Biological process: GO:0090263 [positive regulation of canonical Wnt receptor signaling pathway] evidence: IMP
GeneID:4790 -> Biological process: GO:1900127 [positive regulation of hyaluronan biosynthetic process] evidence: IDA
GeneID:4790 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:4790 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
GeneID:4790 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
GeneID:4790 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:4790 -> Cellular component: GO:0005739 [mitochondrion] evidence: IDA
GeneID:4790 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:4790 -> Cellular component: GO:0033256 [I-kappaB/NF-kappaB complex] evidence: TAS
by
@meso_cacase at
DBCLS
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