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2020-10-24 07:22:51, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_003940               7933 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens ubiquitin specific peptidase 13 (isopeptidase T-3)
            (USP13), mRNA.
ACCESSION   NM_003940
VERSION     NM_003940.2  GI:215598687
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7933)
  AUTHORS   Liu,J., Xia,H., Kim,M., Xu,L., Li,Y., Zhang,L., Cai,Y.,
            Norberg,H.V., Zhang,T., Furuya,T., Jin,M., Zhu,Z., Wang,H., Yu,J.,
            Li,Y., Hao,Y., Choi,A., Ke,H., Ma,D. and Yuan,J.
  TITLE     Beclin1 controls the levels of p53 by regulating the
            deubiquitination activity of USP10 and USP13
  JOURNAL   Cell 147 (1), 223-234 (2011)
   PUBMED   21962518
  REMARK    GeneRIF: USP10 mediates the deubiquitination of p53, regulating
            deubiquitination activity of USP10 and USP13 by Beclin1 provides a
            mechanism for Beclin1 to control the levels of p53.
REFERENCE   2  (bases 1 to 7933)
  AUTHORS   Scortegagna,M., Subtil,T., Qi,J., Kim,H., Zhao,W., Gu,W., Kluger,H.
            and Ronai,Z.A.
  TITLE     USP13 enzyme regulates Siah2 ligase stability and activity via
            noncatalytic ubiquitin-binding domains
  JOURNAL   J. Biol. Chem. 286 (31), 27333-27341 (2011)
   PUBMED   21659512
  REMARK    GeneRIF: study identifies a new layer of Siah2 regulation mediated
            by USP13 binding to ubiquitinated Siah2 protein with a concomitant
            inhibitory effect on its activity under normoxia
REFERENCE   3  (bases 1 to 7933)
  AUTHORS   Zhao,X., Fiske,B., Kawakami,A., Li,J. and Fisher,D.E.
  TITLE     Regulation of MITF stability by the USP13 deubiquitinase
  JOURNAL   Nat Commun 2, 414 (2011)
   PUBMED   21811243
  REMARK    GeneRIF: Through deubiquitination, USP13 stabilizes and upregulates
            MITF protein levels.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7933)
  AUTHORS   Sowa,M.E., Bennett,E.J., Gygi,S.P. and Harper,J.W.
  TITLE     Defining the human deubiquitinating enzyme interaction landscape
  JOURNAL   Cell 138 (2), 389-403 (2009)
   PUBMED   19615732
REFERENCE   5  (bases 1 to 7933)
  AUTHORS   McElhinny,A.S., Kakinuma,K., Sorimachi,H., Labeit,S. and
            Gregorio,C.C.
  TITLE     Muscle-specific RING finger-1 interacts with titin to regulate
            sarcomeric M-line and thick filament structure and may have nuclear
            functions via its interaction with glucocorticoid modulatory
            element binding protein-1
  JOURNAL   J. Cell Biol. 157 (1), 125-136 (2002)
   PUBMED   11927605
REFERENCE   6  (bases 1 to 7933)
  AUTHORS   Timms,K.M., Ansari-Lari,M.A., Morris,W., Brown,S.N. and Gibbs,R.A.
  TITLE     The genomic organization of Isopeptidase T-3 (ISOT-3), a new member
            of the ubiquitin specific protease family (UBP)
  JOURNAL   Gene 217 (1-2), 101-106 (1998)
   PUBMED   9841226
REFERENCE   7  (bases 1 to 7933)
  AUTHORS   D'Andrea,A. and Pellman,D.
  TITLE     Deubiquitinating enzymes: a new class of biological regulators
  JOURNAL   Crit. Rev. Biochem. Mol. Biol. 33 (5), 337-352 (1998)
   PUBMED   9827704
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125604.5, BC016146.1 and AC007687.17.
            On Dec 4, 2008 this sequence version replaced gi:4507848.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U75362.1, BC016146.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025083, ERS025084 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-47                AC125604.5         11738-11784
            48-2736             BC016146.1         1-2689
            2737-7933           AC007687.17        74479-79675         c
FEATURES             Location/Qualifiers
     source          1..7933
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q26.2-q26.3"
     gene            1..7933
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /note="ubiquitin specific peptidase 13 (isopeptidase T-3)"
                     /db_xref="GeneID:8975"
                     /db_xref="HGNC:12611"
                     /db_xref="MIM:603591"
     exon            1..249
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       63
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370443197"
     variation       76
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200016596"
     CDS             82..2673
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /EC_number="3.4.19.12"
                     /note="ubiquitin specific protease 13 (isopeptidase T-3);
                     ubiquitin thiolesterase 13; ubiquitin thioesterase 13;
                     deubiquitinating enzyme 13; ubiquitin-specific-processing
                     protease 13"
                     /codon_start=1
                     /product="ubiquitin carboxyl-terminal hydrolase 13"
                     /protein_id="NP_003931.2"
                     /db_xref="GI:215598688"
                     /db_xref="CCDS:CCDS3235.1"
                     /db_xref="GeneID:8975"
                     /db_xref="HGNC:12611"
                     /db_xref="MIM:603591"
                     /translation="
MQRRGALFGMPGGSGGRKMAAGDIGELLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEGGLYVCMNTFLAFGREHVERHFRKTGQSVYMHLKRHVREKVRGASGGALPKRRNSKIFLDLDTDDDLNSDDYEYEDEAKLVIFPDHYEIALPNIEELPALVTIACDAVLSSKSPYRKQDPDTWENELPVSKYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSGGNGHALEHYRDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHGTENGLQDNDIKLRVSEWEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSDVFRFLVEERIQCCQTRKVRYTERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIPFSACLQAFSEPENVDDFWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFDVSIDMPDLLDINHLRARGLQPGEEELPDISPPIVIPDDSKDRLMNQLIDPSDIDESSVMQLAEMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFGASGLDNQPPEEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEMENNANANIISEAKPEGPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDHKVCASERPPKDLGYMYFYRRIPS
"
     misc_feature    169..2664
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /note="Isopeptidase T [Posttranslational modification,
                     protein turnover, chaperones]; Region: UBP14; COG5207"
                     /db_xref="CDD:34804"
     misc_feature    421..423
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q92995.2); phosphorylation site"
     misc_feature    445..447
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphothreonine; propagated from
                     UniProtKB/Swiss-Prot (Q92995.2); phosphorylation site"
     misc_feature    712..933
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /note="Zn-finger in ubiquitin-hydrolases and other
                     protein; Region: zf-UBP; pfam02148"
                     /db_xref="CDD:202130"
     misc_feature    1090..>1911
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /note="A subfamily of Peptidase C19. Peptidase C19
                     contains ubiquitinyl hydrolases. They are intracellular
                     peptidases that remove ubiquitin molecules from
                     polyubiquinated peptides by cleavage of isopeptide bonds.
                     They hydrolyze bonds involving the carboxyl...; Region:
                     Peptidase_C19B; cd02658"
                     /db_xref="CDD:73064"
     misc_feature    order(1099..1101,1114..1116)
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /note="active site"
                     /db_xref="CDD:73064"
     misc_feature    2041..2154
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /note="Ubiquitin Associated domain. The UBA domain is a
                     commonly occurring sequence motif in some members of the
                     ubiquitination pathway, UV excision repair proteins, and
                     certain protein kinases. Although its specific role is so
                     far unknown, it has been...; Region: UBA; cd00194"
                     /db_xref="CDD:29156"
     misc_feature    order(2071..2079,2152..2154)
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /note="putative protein-protein interaction site; other
                     site"
                     /db_xref="CDD:29156"
     misc_feature    2074..2082
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /note="GFP-loop; other site"
                     /db_xref="CDD:29156"
     misc_feature    2269..2379
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /note="Ubiquitin Associated domain. The UBA domain is a
                     commonly occurring sequence motif in some members of the
                     ubiquitination pathway, UV excision repair proteins, and
                     certain protein kinases. Although its specific role is so
                     far unknown, it has been...; Region: UBA; cd00194"
                     /db_xref="CDD:29156"
     misc_feature    order(2296..2304,2374..2376)
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /note="putative protein-protein interaction site; other
                     site"
                     /db_xref="CDD:29156"
     misc_feature    2299..2307
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /note="GFP-loop; other site"
                     /db_xref="CDD:29156"
     misc_feature    <2485..2658
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /note="Peptidase C19 contains ubiquitinyl hydrolases. They
                     are intracellular peptidases that remove ubiquitin
                     molecules from polyubiquinated peptides by cleavage of
                     isopeptide bonds. They hydrolyse bonds involving the
                     carboxyl group of the C-terminal Gly...; Region:
                     Peptidase_C19; cl02553"
                     /db_xref="CDD:194354"
     misc_feature    order(2548..2550,2596..2598)
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /note="active site"
                     /db_xref="CDD:73062"
     variation       92
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374896625"
     variation       97
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:368406240"
     variation       117
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:193177026"
     variation       142
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373833022"
     variation       156
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144481641"
     variation       176
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:147844491"
     variation       210
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372813389"
     variation       222
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2276803"
     variation       245
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:376341612"
     exon            250..375
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       267
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369204855"
     variation       370
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372042233"
     exon            376..436
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       390
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372822087"
     variation       401
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61760203"
     variation       426
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:145034700"
     variation       433
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:77083687"
     exon            437..558
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       439
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:375786336"
     variation       452
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149046448"
     variation       464
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144680708"
     variation       492
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370081055"
     exon            559..701
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       583
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367898662"
     variation       625
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141550831"
     variation       660
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:145278369"
     variation       699
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:16830742"
     exon            702..886
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       723
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11917211"
     variation       730
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:150877602"
     variation       731
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61760204"
     variation       742
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:373424435"
     variation       759
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149578113"
     variation       808
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:201476527"
     variation       813
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147276718"
     variation       815
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200478981"
     variation       816
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140845211"
     variation       853
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144601583"
     variation       868
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369493333"
     exon            887..981
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       900
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:35551105"
     variation       924
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:201368964"
     variation       928
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:147887335"
     variation       947
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200404045"
     variation       948
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148480598"
     variation       958
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199612648"
     variation       965
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201751513"
     variation       980
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:368347151"
     exon            982..1169
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       994
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:75426377"
     variation       1051
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200842164"
     variation       1055
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143703894"
     variation       1088
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200851300"
     variation       1089
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:115755648"
     variation       1092
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:140837171"
     exon            1170..1241
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       1205
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200580330"
     variation       1240
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199508428"
     exon            1242..1335
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       1251
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141041980"
     variation       1289
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375364459"
     variation       1315
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199512457"
     exon            1336..1461
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       1347
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140760133"
     variation       1360
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377063095"
     variation       1361
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368929380"
     variation       1455
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114841413"
     exon            1462..1615
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       1468
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200090282"
     variation       1474
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61750381"
     variation       1491
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140308745"
     variation       1510
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377643136"
     variation       1518
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202017744"
     variation       1519
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200761055"
     variation       1520
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200026200"
     variation       1540
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145234029"
     variation       1549
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373942034"
     variation       1557
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35132005"
     variation       1564
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114235967"
     variation       1568
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200979122"
     variation       1578
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143824486"
     variation       1601
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201920993"
     variation       1602
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201509551"
     exon            1616..1790
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       1627
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:144016604"
     variation       1667
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:145621262"
     variation       1678
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:147308215"
     variation       1687
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139131420"
     variation       1741
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369543896"
     exon            1791..1879
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       1800
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185902975"
     variation       1813
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:192477140"
     variation       1861
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377320828"
     exon            1880..2002
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       1925
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374433568"
     variation       1966
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143157721"
     variation       1972
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:147444783"
     variation       1974
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:61750382"
     variation       1977
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:377395498"
     variation       1996
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370742776"
     exon            2003..2029
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       2005
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149947980"
     exon            2030..2173
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       2068
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61733591"
     variation       2087
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111274613"
     variation       2096
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200079140"
     variation       2120
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148697387"
     variation       2128
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368763882"
     exon            2174..2340
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       2185
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:368608414"
     variation       2186
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373170651"
     variation       2277
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:76353089"
     variation       2333
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184549998"
     exon            2341..2494
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       2356
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199954201"
     variation       2377
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:201209313"
     variation       2464
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146739336"
     variation       2488..2489
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:35852624"
     exon            2495..2579
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       2579
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140288498"
     exon            2580..7933
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /inference="alignment:Splign:1.39.8"
     variation       2590
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:187540816"
     variation       2640
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371360955"
     variation       2644
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199943847"
     variation       2645
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202177426"
     variation       2646
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144044913"
     variation       2653
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:34456126"
     variation       2684
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201230992"
     variation       2701
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200310337"
     variation       2709
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367912011"
     variation       2725..2726
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:201974472"
     variation       2726..2727
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:71300409"
     variation       2750
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:75011052"
     variation       2765
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:193041153"
     variation       2820
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:114012075"
     variation       2897
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:7646699"
     variation       2970
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:111790665"
     variation       3389..3390
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:61465697"
     variation       3440
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:75971703"
     variation       3441
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146600298"
     variation       3480
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:17195990"
     variation       3485
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:184863751"
     variation       3565
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111295201"
     variation       3622
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368400568"
     variation       3751
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370933946"
     variation       3966
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:141370768"
     variation       4033
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114520378"
     variation       4063
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143691431"
     variation       4079
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:188400981"
     variation       4085
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151261728"
     variation       4094
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:192681074"
     variation       4136
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114339410"
     variation       4287
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:116146261"
     variation       4336
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113472679"
     STS             4487..4606
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /standard_name="RH93958"
                     /db_xref="UniSTS:88187"
     variation       4502
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184674078"
     variation       4550
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140502990"
     variation       4575..4577
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace=""
                     /replace="aga"
                     /db_xref="dbSNP:144014392"
     variation       4577..4579
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace=""
                     /replace="aag"
                     /db_xref="dbSNP:71726872"
     variation       4577
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:77642379"
     variation       4578
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace=""
                     /replace="aag"
                     /db_xref="dbSNP:78667934"
     variation       4593
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:116718754"
     variation       4695
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:187971271"
     variation       4781
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:12486162"
     variation       4936
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113822484"
     variation       4939
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:192542476"
     variation       4969
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:72622569"
     variation       4990
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:184584118"
     variation       5025
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189033728"
     variation       5053
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:9814513"
     variation       5067
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138160305"
     variation       5154
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376502830"
     variation       5183
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371022756"
     variation       5287
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:149105404"
     variation       5289
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:60621113"
     variation       5407
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:146223250"
     variation       5442
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:79270592"
     variation       5454
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370020175"
     variation       5635
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:76174245"
     STS             5748..5865
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /standard_name="D3S2768E"
                     /db_xref="UniSTS:150810"
     variation       5841
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138822337"
     variation       5971
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:182106680"
     variation       5981
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375755665"
     variation       5988
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:142841682"
     variation       6136
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:79909042"
     variation       6186
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:147997061"
     variation       6226
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141691568"
     variation       6250
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150502110"
     variation       6265
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377264179"
     variation       6269
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:186677724"
     variation       6282
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189995958"
     variation       6299
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139478047"
     variation       6365
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:181256392"
     variation       6418
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376338210"
     variation       6608
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:7624986"
     variation       6680
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144496906"
     variation       6731
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185317332"
     variation       6751
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:146167066"
     variation       6755
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:189683316"
     variation       6849
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371210506"
     variation       6879
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:368580136"
     variation       6963
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201780791"
     variation       7145
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183440702"
     variation       7226
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10937010"
     variation       7415
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:199517459"
     variation       7444
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143758106"
     variation       7465
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:3732993"
     STS             7511..7647
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /standard_name="RH99087"
                     /db_xref="UniSTS:85603"
     variation       7526
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace=""
                     /replace="gg"
                     /db_xref="dbSNP:71762010"
     variation       7665
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:376483153"
     variation       7713
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145820187"
     variation       7748
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:15241"
     variation       7797
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148946968"
     variation       7822
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1045545"
     variation       7871..7872
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:34291984"
     variation       7904
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142884655"
     variation       7929
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186343183"
     variation       7933
                     /gene="USP13"
                     /gene_synonym="IsoT-3; ISOT3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191891819"
ORIGIN      
gctcgctggcgccgccgccgccggcagaccccgcgctccggctccggctcggctcgctcggctccggtgcgcgccgaggccatgcagcgccggggcgccctgttcggcatgccgggcggcagcggaggcaggaagatggctgcaggagacatcggcgagctgctagtgccccacatgcccacgatccgcgtgcccaggtccggcgacagggtctacaagaacgagtgcgccttctcctacgactctcccaattctgaaggtggactctatgtatgcatgaatacatttttggcctttggaagggaacatgttgaaagacattttcgaaaaactggacagagtgtatacatgcacctgaaaagacatgtgcgagagaaggtaagaggggcgtctggtggagcgttaccaaaaaggaggaattccaagatttttttagatctagatactgatgacgatttaaatagcgacgattatgaatatgaagatgaagccaaacttgttatattcccagatcactatgaaatagcactaccaaatattgaggagttaccagccctggtaacaattgcttgtgatgcagttctcagctcaaaatctccatacagaaagcaggacccagacacgtgggaaaatgaattgccagtatctaaatatgccaacaacctcacccagctggacaatggagtcaggattcctccaagtggttggaagtgtgccagatgcgacctgcgagaaaacctctggttgaatctgactgacggctctgtcctgtgtggaaagtggttctttgacagctctgggggcaacgggcatgcgctggagcattacagagacatgggctacccactagccgtgaaactgggaaccatcactcctgacggggcagatgtttattcttttcaagaagaagaacctgttttggatcctcatttggccaagcacttagcgcattttggaattgatatgcttcatatgcatgggacagagaatgggctccaggacaatgacatcaagctgagggtcagtgagtgggaagtgatccaggagtcgggcacgaaactgaagccaatgtatggtcctggctacacgggtctgaagaacctgggcaacagctgctatctcagctctgtcatgcaggccatcttcagcatcccagaattccagagagcgtatgtaggaaaccttcccagaatatttgactactcgcctttagatccaacacaagatttcaacacacagatgactaagttaggacatggccttctctcaggccagtattcaaagcctccggtgaaatctgaactcattgaacaggtgatgaaggaggagcacaagccacagcagaacgggatctctccgcgcatgtttaaggcctttgtaagcaagagccacccggaattctcctctaacaggcagcaagatgcccaggaattcttcttgcacctggtgaatctagtagagaggaaccgcatcggctcagaaaacccaagcgatgtttttcgttttttggtggaagaacgcattcagtgctgtcagacccggaaagtccgctacacggagagggtggattacctgatgcagttacctgtggccatggaggcggcaaccaacaaggatgaactgatcgcttatgaactaacgagaagggaagcagaagcaaacagaagaccccttcctgagttggtacgtgccaagataccatttagtgcctgccttcaggccttctctgaaccagaaaatgttgatgatttctggagcagtgccctacaagcaaagtctgcgggtgtgaaaacatctcgctttgcttcattccctgaatacttggtagtgcagataaagaagttcacttttggtcttgactgggttcccaaaaaatttgatgtttctattgatatgccagacctacttgatatcaaccatctccgagccagggggttacagccaggagaggaagaacttccagacatcagcccccccatagtcattcctgatgactcaaaagatcgcctgatgaaccaattgatagacccatcagacatcgatgagtcatcagtgatgcagctggccgagatgggtttcccgctggaagcatgtcgcaaggctgtgtacttcactggaaatatgggcgccgaggtggccttcaactggatcattgttcacatggaagagccagattttgctgagccgctgaccatgcctggttatggaggggcagcttctgctggagcctctgtttttggtgcttctggactggataaccaacctccagaggaaatcgtagctatcatcacctccatgggatttcagcgaaatcaggctattcaggcactacgagcaacgaataataacctggaaagagcactggattggatctttagccaccctgagtttgaagaagacagtgattttgtgattgagatggagaataatgccaatgcaaacattatttctgaggccaagcccgaaggacctagagtcaaggatggatctggaacatatgagctatttgcattcatcagtcacatgggaacatccacaatgagtggtcattacatttgccatatcaaaaaggaaggaagatgggtgatttacaatgaccacaaagtttgtgcctcagaaaggccccctaaagacctgggctacatgtacttttaccgcaggataccaagctaaacctcaaatataaaaattggcgaaaagaagccatacgcctttttaatttgccaaaaaaaaaaagaagaagaagaagttgaaacaactagacatgaaggaatatatggggtatttatcgtttatttaaagagcacgatcagttgacaccttctgaaatagaactgagaagaaatttctattagtgatgatacactattatattgtagatagtttttataaatgttcaaaaagatgatgatatttaaaaacaaaaaaagtattcatattgctggtggaggatctgccatcagcacatcaaaaatggggatgtgcccccagccctctattttgctttgggggtcagtgatagtggcctctggagaaaccaaataatgtggccagtggtgtggccttacccacaacaaatgaaaagcccacttgtgtttcatatagaaaatcagcagttgggtggggctttatttgtgacataatttttttcatgacatacaataatttctgatgtatccatgtagatattatgctctgtccataatagagcctctgcaatgaaagatatttttaatttgtcacattaaaattcataatacgattgtgtgaatgtgtgtgagactgactgagagtgtgagacttttactagaaaagtgagtccactagaaaatctgtgacaagttggtttttaaagtctgaacagttgatattaagcatatctgaaaaaagcaagtaaatattttaacaaaactatgactcaggaaccttcgagaagattagttccccacttagatttttaaggagtaaaaagggctgagttatgcctttaagtgctgtcaagaattcacttgggtttgggacatttgctggtgtaatgctagatgcccacagcagcataatattgtactttgtcaaaggtaggtaaattctctgtttctcagcagccctttccccaaaaggtatggtgtttatttttagtaaaaatagctaatctctttttaccatctcacatgataactctttggagtcatgtcaagtgccccaaatttgtctgtgattttcccatctctgagctctttatctgcctccgtttccttgtttttctggggccagagtctcatctctgcctttttttggtgtatcaccttctgacttgccttcattgcttgtctgatgtgaccaacagtgtgatcttggacacactaaggattttagatgcaaagaaactttatacaacattatgaaagactatcctttccattttggttatttcagcattttagttgcaacctgggattagattagagtttccaacgtgatgaaaagtggaatgatagcattctataatttccataattttcctactggtccgtaccaaattctagagtctctggagttgctatttcagagtatttggtcaaacgaaaaagaatttattgctgtctgtttaacatgtatttgtttggttgaaaggatctttttagaaactgtaggaaaataaacagaaccaaccaggtgaaacaaagcacagacattgggttaggatgtagtgagttgtgaacaatcaggattctgggtgtgatgggggtccctgtctcataggtgatcctttggtgccatgtgaccgagagacatggtgtctaaggcccatggcctggagacctgggtgctgctcctagctgactgtggaccttgggcaagtccttcatccgtcctgtgcctcactgtcctcatctgaacaatggtatgatgacacctgccctctctttcaatcatgctttgaggatacagtgagattggttacagtgaaccttcaatgagtagaatgtggtatgccatggtgggttgtagtagatggtgctccctgccttttctcctctgttttcctcaatttgggaacaaatgagattggcagaaggagggagctcacggtgcagtacttttctaccaaagtgtgcccactggtgtcacctcctaatgttaacttggatttcctaaagcagtcccactctgttatgagagtcactgactcccgtggacatccccacagtaagcagccttacaaaatccagtccccttagggcagagtgagtgtcatagaataatgactccaaacccacgtcaaaaatggcttgttttcagcgatgttataaaacaaaggcctgttttttggaattgggggtgactgggtggtttggattgaaatgtggacaaagatagcatgtgtattttgaataaaataaaaattttgtaataaaacttttaaaaatcagtgatgtaaaatcaatatttaagactataggctataaattgtttgatttcattaactagcccttttgatgcctagacatgttgtaaaaaaattgtgctatggctgccttttcttctgccccacaacacaaagggctatttctacaaggcaaagttttgtatatgtgctattctttacttcagattgagagttgggaaaaactggagtaaataatgggtttcttacttgcttaaaagcatatttatatgtgtatctcaatatatacaaggcaggttcccctataaaagtctggaatgtactgcttaattttacacttgtgtagacacgattatttgtgactgaaaagtggaataacgtgtggattttgtcaactcattatcagtctgttagcagtcctctatgtgaggcatggtggtctaattgtgaaattctccctgtatatgggtgtctgtgtgaaagacagcactttcttcctgtaaatatcttttgatatccatttatgtagaattccaatgaatatgtctttggaaaaggtaatgtatcaaagtttttattttgccaattgatctaaatgcccatataactaatcagaaatccagtttggttcagattgggattttcttttaaagaaaaaaaaagtatgcagaaaagactattggaagaatcatgtgttagtgacactttacatcaacgttgcttcaatattttggaattgaccaggctgctttctcctacctgcaagagaatgtgcctgacatttcccagtgcttactttgggctataggaagtccagcggggatagctcgagcctcttgctccctgagtcatttattccctttacctgaacagagccttacctgcaattcatagtgagagcacctgggtctgtatcctgactccactctaagtgaggtgggactgaatcactgtacctctctgggccttttcatttgaaacaagtgggttagactagattagctccaaagtcctctcttgccctaacattttatttttattttcctgtggttaccactagggtctgacacgtaaaatgtgagggatcacttagaggtttggatgttatatttttgcattgttacagcttatactccccagttgaggacctgtgtcattcttagtggccccacgacccctctgtttgtattcctgctccacttatctatacttttttgggtaatcatcccactttttttttttcttgagatggagtctcgctgtgttgccaaggctggagtacagtggtgcaatctcagctcactgcagcctcctcccgggttcaagtgattctcctgcctcagcttcccaagtagctgggattactggcgcacgccactacgcccagctaatttttgtatttttagtagagacagggttttgccatgttggccaggctggtcttgaactcttgacctcaacctgcctcagcctcccaaagtgctgggattacacgcatgagctaccgcgtccagccccactttttttctactcttgaaaaaaacaactttctagtccatgaggtactttggctccatccccctcaaaaacaaaacaaaaaatccatttaaagtgtcctcctagaaaagcctcagaactgccttcaactacatctgtcacctttatagaatattttgaaattctggaagaggatgggaaacaaaattctaatttagctagagctgtgatccccaaataagtgctgacaaaattgtctaccacagaaaggccgtccttgtcatcttgtaggcatcactgctgctaaatcacatcagtacatgccttctgtggggagatggcagggggcaggggcaggaccaggggatgggattagataaagtgtgataatgtcctttagataaaagaaatcctacgctatagaacaaggttctgtactcttgagttggtgtctgagatcacctgcacagtgttacagagattttccactccataaatcactctaaaagagtttgcataagactcggtagacctgtgctattcaatgtggcagtcaacagccatatgtggcgatgactactcaaagtttggcttgttcaaatcgagactgtgttgtacacatacaatacacaccagattttgaaggcttggtaccaaaaaggaatttaaaatatttcaccaatatttcatattgataacatgctgaaatgacactattttggatgtactaagtaaaatattaacaatttaatatatttatataattgaaattaaaattcttttcacccatttttatttttttaaaaatgtggcccctaaagaacttcaaattagacatgtggataacgttatacttctattggacagccccactctagacttacatggtgtggggtaggcagtgaaatccgtaaataggaaacgcaattctgcaaagtatctaaatagacagaaacaacacaaatatttttgctggagtcaggagcactgtgaggcacagaacatctcccagaaagcagattttttttttctgccgaaaaaccaatatatatatgtatgatcccaattaaaagacaaaagcaaatgagccccaaactgcctgtcttcagctttgcctgggagctgctacctttgctcttctagcatcttctaggtaccaaggatattagccacttgagggtgttgggcatatttgtttcattgtaggcaaaatcctcttgtggtttcccctccccaggtattgttgagtctgttcaaagctgggtgtgttgaaacactgcacaaatcctgccactcttgatgtgccgcttgtctcagccttggcagaggctgagtctgttcctgtgcccacctgtccagcaggttttgatgttggctcctgaaagagtttgtatttattttattttgcactagtcacagttgttgttaaactgtatcaaatgttttgggagattatttgcctgagatggaaagagagatggatgatttattgcttcaattgttttaaattaaaagctattctcacaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:8975 -> Molecular function: GO:0004197 [cysteine-type endopeptidase activity] evidence: IMP
            GeneID:8975 -> Molecular function: GO:0004221 [ubiquitin thiolesterase activity] evidence: IDA
            GeneID:8975 -> Molecular function: GO:0004843 [ubiquitin-specific protease activity] evidence: IDA
            GeneID:8975 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:8975 -> Molecular function: GO:0008242 [omega peptidase activity] evidence: IEA
            GeneID:8975 -> Molecular function: GO:0008270 [zinc ion binding] evidence: IEA
            GeneID:8975 -> Molecular function: GO:0031625 [ubiquitin protein ligase binding] evidence: IPI
            GeneID:8975 -> Molecular function: GO:0043130 [ubiquitin binding] evidence: IDA
            GeneID:8975 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: IMP
            GeneID:8975 -> Biological process: GO:0006511 [ubiquitin-dependent protein catabolic process] evidence: IEA
            GeneID:8975 -> Biological process: GO:0006914 [autophagy] evidence: IEA
            GeneID:8975 -> Biological process: GO:0008283 [cell proliferation] evidence: IMP
            GeneID:8975 -> Biological process: GO:0010506 [regulation of autophagy] evidence: IDA
            GeneID:8975 -> Biological process: GO:0030318 [melanocyte differentiation] evidence: TAS
            GeneID:8975 -> Biological process: GO:0050821 [protein stabilization] evidence: IDA
            GeneID:8975 -> Biological process: GO:0070536 [protein K63-linked deubiquitination] evidence: IDA
ANNOTATIONS from NCBI Entrez Gene (20130726):
            NP_003931 -> EC 3.4.19.12

by @meso_cacase at DBCLS
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