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2019-03-25 14:32:44, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_003760               6041 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens eukaryotic translation initiation factor 4 gamma, 3
            (EIF4G3), transcript variant 3, mRNA.
ACCESSION   NM_003760
VERSION     NM_003760.4  GI:311771747
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6041)
  AUTHORS   Beausoleil,S.A., Villen,J., Gerber,S.A., Rush,J. and Gygi,S.P.
  TITLE     A probability-based approach for high-throughput protein
            phosphorylation analysis and site localization
  JOURNAL   Nat. Biotechnol. 24 (10), 1285-1292 (2006)
   PUBMED   16964243
REFERENCE   2  (bases 1 to 6041)
  AUTHORS   Lejeune,F., Ranganathan,A.C. and Maquat,L.E.
  TITLE     eIF4G is required for the pioneer round of translation in mammalian
            cells
  JOURNAL   Nat. Struct. Mol. Biol. 11 (10), 992-1000 (2004)
   PUBMED   15361857
REFERENCE   3  (bases 1 to 6041)
  AUTHORS   Gradi,A., Foeger,N., Strong,R., Svitkin,Y.V., Sonenberg,N.,
            Skern,T. and Belsham,G.J.
  TITLE     Cleavage of eukaryotic translation initiation factor 4GII within
            foot-and-mouth disease virus-infected cells: identification of the
            L-protease cleavage site in vitro
  JOURNAL   J. Virol. 78 (7), 3271-3278 (2004)
   PUBMED   15016848
REFERENCE   4  (bases 1 to 6041)
  AUTHORS   Qin,H., Raught,B., Sonenberg,N., Goldstein,E.G. and Edelman,A.M.
  TITLE     Phosphorylation screening identifies translational initiation
            factor 4GII as an intracellular target of
            Ca(2+)/calmodulin-dependent protein kinase I
  JOURNAL   J. Biol. Chem. 278 (49), 48570-48579 (2003)
   PUBMED   14507913
REFERENCE   5  (bases 1 to 6041)
  AUTHORS   Miura,T., Shiratori,Y. and Shimma,N.
  TITLE     Backbone resonance assignment of human eukaryotic translation
            initiation factor 4E (eIF4E) in complex with 7-methylguanosine
            diphosphate (m7GDP) and a 17-amino acid peptide derived from human
            eIF4GII
  JOURNAL   J. Biomol. NMR 27 (3), 279-280 (2003)
   PUBMED   12975586
REFERENCE   6  (bases 1 to 6041)
  AUTHORS   Waskiewicz,A.J., Johnson,J.C., Penn,B., Mahalingam,M., Kimball,S.R.
            and Cooper,J.A.
  TITLE     Phosphorylation of the cap-binding protein eukaryotic translation
            initiation factor 4E by protein kinase Mnk1 in vivo
  JOURNAL   Mol. Cell. Biol. 19 (3), 1871-1880 (1999)
   PUBMED   10022874
REFERENCE   7  (bases 1 to 6041)
  AUTHORS   Pyronnet,S., Imataka,H., Gingras,A.C., Fukunaga,R., Hunter,T. and
            Sonenberg,N.
  TITLE     Human eukaryotic translation initiation factor 4G (eIF4G) recruits
            mnk1 to phosphorylate eIF4E
  JOURNAL   EMBO J. 18 (1), 270-279 (1999)
   PUBMED   9878069
REFERENCE   8  (bases 1 to 6041)
  AUTHORS   Gingras,A.C., Raught,B. and Sonenberg,N.
  TITLE     eIF4 initiation factors: effectors of mRNA recruitment to ribosomes
            and regulators of translation
  JOURNAL   Annu. Rev. Biochem. 68, 913-963 (1999)
   PUBMED   10872469
  REMARK    Review article
REFERENCE   9  (bases 1 to 6041)
  AUTHORS   Imataka,H., Gradi,A. and Sonenberg,N.
  TITLE     A newly identified N-terminal amino acid sequence of human eIF4G
            binds poly(A)-binding protein and functions in poly(A)-dependent
            translation
  JOURNAL   EMBO J. 17 (24), 7480-7489 (1998)
   PUBMED   9857202
REFERENCE   10 (bases 1 to 6041)
  AUTHORS   Gradi,A., Imataka,H., Svitkin,Y.V., Rom,E., Raught,B., Morino,S.
            and Sonenberg,N.
  TITLE     A novel functional human eukaryotic translation initiation factor
            4G
  JOURNAL   Mol. Cell. Biol. 18 (1), 334-342 (1998)
   PUBMED   9418880
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF012072.2, BC094683.1, AB209119.1 and BF084093.1.
            On Nov 10, 2010 this sequence version replaced gi:115529454.
            
            Transcript Variant: This variant (3) lacks an in-frame exon in the
            CDS, as compared to variant 1. The resulting isoform (3) lacks an
            internal segment, as compared to isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: AF012072.2 [ECO:0000331]
            RNAseq introns       :: mixed/partial sample support ERS025081,
                                    ERS025082 [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4093              AF012072.2         1-4093
            4094-5213           BC094683.1         3101-4220
            5214-5850           AB209119.1         5557-6193
            5851-5854           AF012072.2         5851-5854
            5855-6041           BF084093.1         94-280
FEATURES             Location/Qualifiers
     source          1..6041
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.12"
     gene            1..6041
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /note="eukaryotic translation initiation factor 4 gamma,
                     3"
                     /db_xref="GeneID:8672"
                     /db_xref="HGNC:3298"
                     /db_xref="HPRD:06802"
                     /db_xref="MIM:603929"
     misc_feature    29..31
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /note="upstream in-frame stop codon"
     CDS             257..5014
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /note="isoform 3 is encoded by transcript variant 3;
                     eIF-4-gamma 3; eIF-4-gamma II"
                     /codon_start=1
                     /product="eukaryotic translation initiation factor 4 gamma
                     3 isoform 3"
                     /protein_id="NP_003751.2"
                     /db_xref="GI:10092601"
                     /db_xref="CCDS:CCDS214.1"
                     /db_xref="GeneID:8672"
                     /db_xref="HGNC:3298"
                     /db_xref="HPRD:06802"
                     /db_xref="MIM:603929"
                     /translation="
MNSQPQTRSPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPAQIAITVPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLKKVKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQYDREFLLDFQFMPACIQKPEGLPPISDVVLDKINQPKLPMRTLDPRILPRGPDFTPAFADFGRQTPGGRGVPLLNVGSRRSQPGQRREPRKIITVSVKEDVHLKKAENAWKPSQKRDSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLTVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQKEFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERKTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTKEKRRPGVQRVDEGGWNTVQGAKNSRVLDPSKFLKITKPTIDEKIQLVPKAQLGSWGKGSSGGAKASETDALRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLTSRGSMGREKNDKPLPSATARPNTFMRGGSSKDLLDNQSQEEQRREMLETVKQLTGGVDVERNSTEAERNKTRESAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHINDFKEAMQCVEELNAQGLLHVFVRVGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLLSEILHLLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEALSKKELSAEELYKRLEKLIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAIIADSSTFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN
"
     misc_feature    656..742
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (O43432.2);
                     Region: PABPC1-binding"
     misc_feature    944..946
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (O43432.2); phosphorylation site"
     misc_feature    944..946
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    950..952
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (O43432.2); phosphorylation site"
     misc_feature    950..952
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1739..1741
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (O43432.2); phosphorylation site"
     misc_feature    1739..1741
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    2111..2146
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (O43432.2);
                     Region: EIF4E-binding (By similarity)"
     misc_feature    2351..3313
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (O43432.2);
                     Region: eIF3/EIF4A-binding (By similarity)"
     misc_feature    2351..2356
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Cleavage, by enterovirus/rhinovirus protease 2A;
                     propagated from UniProtKB/Swiss-Prot (O43432.2); cleavage
                     site"
     misc_feature    2354..2359
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Cleavage, by foot-and-mouth disease virus leader
                     protease; propagated from UniProtKB/Swiss-Prot (O43432.2);
                     cleavage site"
     misc_feature    2519..3196
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /note="MIF4G domain; Region: MIF4G; pfam02854"
                     /db_xref="CDD:202432"
     misc_feature    2921..2923
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (O43432.2); phosphorylation site"
     misc_feature    3722..3724
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine, by CaMK1; propagated from
                     UniProtKB/Swiss-Prot (O43432.2); phosphorylation site"
     misc_feature    3722..3724
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /citation=[4]
                     /db_xref="HPRD:05412"
     misc_feature    3941..4258
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /note="MA3 domain; Region: MA3; pfam02847"
                     /db_xref="CDD:111714"
     misc_feature    4481..4483
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    4538..4924
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /note="C-terminal W2 domain of eukaryotic translation
                     initiation factor 4 gamma 1 and similar proteins; Region:
                     W2_eIF4G1_like; cd11559"
                     /db_xref="CDD:211397"
     misc_feature    4553..5011
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (O43432.2);
                     Region: EIF4A-binding (By similarity)"
     misc_feature    <4859..4999
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /note="C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon;
                     Region: W2; cl17013"
                     /db_xref="CDD:212634"
     misc_feature    4967..5011
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (O43432.2);
                     Region: Necessary but not sufficient for MKNK1-binding (By
                     similarity)"
     variation       1025
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1062981"
     STS             2346..2469
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /standard_name="SHGC-74327"
                     /db_xref="UniSTS:69800"
     variation       3811
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2230572"
     variation       4094
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2230573"
     STS             5086..5226
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /standard_name="SHGC-74345"
                     /db_xref="UniSTS:77072"
     STS             5092..5215
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /standard_name="EST28C5"
                     /db_xref="UniSTS:263320"
     STS             5175..5935
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /standard_name="EIF4G3_1535"
                     /db_xref="UniSTS:277201"
     STS             5618..5697
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /standard_name="SHGC-74329"
                     /db_xref="UniSTS:83013"
ORIGIN      
caatcccacagagtattgatgaggaaactgaagtttggagcgatcacatcattttcccaaggtaacacaagtggcaagacagccgggaacccctaccccatccccttattcagcacatgaaataaacaaggggcatccaaatcttgcggcaacgcccccgggacatgcatcgtcccctggactctctcaaaccccttatccctctggacagaatgcaggtccaaccacgctggtataccctcaaacccctcagacaatgaattcacaacctcaaacccgttctccgtttttccagaggcctcaaatacagcctcctagagctaccatcccgaacagcagtccttccattcgtcctggtgcacagacacccactgcagtgtaccaggctaatcagcacatcatgatggttaaccatctgcccatgccgtacccagtgccccaggggcctcagtactgtataccacagtaccgtcatagtggccctccttatgttgggcccccccaacaatatccagttcaaccaccggggccaggtcctttttatcctggaccaggacctggggacttccccaatgcttatggaacgcctttttacccaagtcagccggtgtatcagtcagcacctatcatagtgcctacgcagcaacagccgcctccagccaagagagagaaaaaaactataagaattcgggatccaaaccagggaggtaaagacataacagaggagattatgtctggaggtggcagcagaaatcctactccacccataggaagacccacgtccacacctactcctcctcagcagctgcccagccaggtccccgagcacagccctgtggtttatgggactgtggagagcgctcatcttgctgccagcacccctgtcactgcagctagcgaccagaagcaagaggagaagccaaaaccagatccagtgttaaagtctccttccccagtccttaggctagtcctcagtggagagaagaaagaacaagaaggccagacatctgaaactactgcaatagtatccatagcagagcttcctctgcctccatcacctaccactgtttcttctgttgctcgaagtacaattgcagcccccacctcttctgctcttagtagccaaccaatattcaccactgctatagatgacagatgtgaactctcatccccaagagaagacacaattcctatacccagcctcacatcttgcacagaaacatcagaccctttaccaacaaatgaaaatgatgatgatatatgcaagaaaccctgtagtgtagcacctaatgatattccactggtttctagtactaacctaattaatgaaataaatggagttagcgaaaaattatcagccacggagagcattgtggaaatagtaaaacaggaagtattgccattgactcttgaattggagattctcgaaaatcccccagaagaaatgaaactggagtgtatcccagctcccatcaccccttccacagttccttcctttcctccaactcctccaactcctccagcttctcctcctcacactccagtcattgttcctgctgctgccactactgttagttctccgagtgctgccatcacagtccagagagtcctagaggaggacgagagcataagaacttgccttagtgaagatgcaaaagagattcagaacaaaatagaggtagaagcagatgggcaaacagaagagattttggattctcaaaacttaaattcaagaaggagccctgtcccagctcaaatagctataactgtaccaaagacatggaagaaaccaaaagatcggacccgaaccactgaagagatgttagaggcagaattggagcttaaagctgaagaggagctttccattgacaaagtacttgaatctgaacaagataaaatgagccaggggtttcatcctgaaagagacccctctgacctaaaaaaagtgaaagctgtggaagaaaatggagaagaagctgagccagtacgtaatggtgctgagagtgtttctgagggtgaaggaatagatgctaattcaggctccacagatagttctggtgatggggttacatttccatttaaaccagaatcctggaagcctactgatactgaaggtaagaagcagtatgacagggagtttctgctggacttccagttcatgcctgcctgtatacaaaaaccagagggcctgcctcctatcagtgatgtggttcttgacaagatcaaccaacccaaattgccaatgcgaactctggatcctcgaattttgcctcgaggaccagactttacaccagcctttgctgattttggaaggcagacacctggtggaagaggcgtacctttgttgaatgttgggtcacgaagatctcaacctggccaaagaagagaacccagaaagatcatcacagtttctgtaaaagaagatgtacacctgaaaaaggcagaaaatgcctggaagccaagccaaaaacgagacagccaagccgatgatcccgaaaacattaaaacccaggagctttttagaaaagttcgaagtatcttaaataaattgacaccacagatgttcaatcaactgatgaagcaagtgtcaggacttactgttgacacagaggagcggctgaaaggagttattgacctggtctttgagaaggctattgatgaacccagtttctctgtggcttacgcaaacatgtgtcgatgtctagtaacgctgaaagtacccatggcagacaagcctggtaacacagtgaatttccggaagctgctactgaaccgttgccagaaggagtttgaaaaagataaagcagatgatgatgtctttgagaagaagcagaaagaacttgaggctgccagtgctccagaggagaggacaaggcttcatgatgaactggaagaagccaaggacaaagcccggcggagatccattggcaacatcaagtttattggagaactctttaaactcaaaatgctgactgaagccatcatgcatgactgtgtggtgaagctgctaaagaaccatgatgaagaatccctggagtgcctgtgtcgcctgctcaccaccattggcaaagacttggactttgaaaaagcaaagccacgtatggaccagtactttaatcagatggagaaaattgtgaaagaaagaaaaacctcatctaggattcggttcatgcttcaagatgttatagacctaaggctgtgcaattgggtatctcgaagagcagatcaagggcctaaaactatcgaacagattcacaaagaggctaaaatagaagaacaagaagagcaaaggaaggtccagcaactcatgaccaaagagaagagaagaccaggtgtccagagagtggacgaaggtgggtggaacactgtacaaggggccaagaacagtcgggtactggacccctcaaaattcctaaaaatcactaagcctacaattgatgaaaaaattcagctggtacctaaagcacagctaggcagctggggaaaaggcagcagtggtggagcaaaggcaagtgagactgatgccttacggtcaagtgcttccagtttaaacagattctctgccctgcaacctccagcaccctcagggtccacgccatccacgcctgtagagtttgattcccgaaggaccttaactagtcgtggaagtatgggcagggagaagaatgacaagccccttccatctgcaacagctcggccaaatactttcatgaggggtggcagcagtaaagacctgctagacaatcagtctcaagaagagcagcggagagagatgctggagaccgtgaagcagctcacaggaggtgtggatgtggagaggaacagcactgaggctgagcgaaataaaacaagggagtcagcaaaaccagaaatttcagcaatgtcagctcatgacaaggctgcattatcagaagaggaactggagaggaagtcgaaatctatcattgatgaatttctacacattaatgattttaaggaagccatgcagtgtgtggaagagctgaatgcccagggcctactacatgtttttgtgagagtgggagtggagtccaccctggaaaggagccagatcaccagggatcacatgggccaattactctatcagctggtacagtcagaaaaactcagcaaacaggactttttcaaaggtttttcagaaactttggaattggcagatgacatggccattgatattccccatatttggttgtaccttgctgaactggtgacccccatgttaaaagaaggtggaatctccatgagagaacttaccatagaatttagcaaacctttacttcctgttggaagagctggggtcttgctatctgaaatattgcacctactatgcaaacaaatgagccataagaaagtgggagccttatggagggaggctgacctcagctggaaggactttttaccagaaggagaagatgtacataattttcttttggagcagaagttggacttcatagagtctgacagtccctgttcctctgaagcactttcaaagaaagaactgtctgccgaagagctgtataagcgactcgagaaactcattattgaggacaaagcgaatgatgaacagatctttgactgggtagaggctaatctagacgaaatccagatgagttcacctacattccttagagctttaatgactgctgtttgtaaagcagctattatagccgactcttctaccttcagagtggacactgctgttatcaagcagagagtgccgatcttactcaagtacctagactcagatacagagaaggaactgcaagcactttatgcactacaagcatcgatagtaaaacttgatcaacctgccaatttgctgcggatgttttttgattgtctatatgacgaggaggtgatctccgaggatgccttctacaaatgggagagcagcaaggaccctgcagagcagaatgggaagggcgtggctctgaaatctgtcacggcattcttcacgtggctgcgggaagcagaagaggagtctgaggataactaaaacttcaaatacacaaaatgaaacaaaagaaacaatttaagtatttttttaaaaagtttcacgtcttcgccaatcacagtgcagcaaggccaattctcgcagaaacccccacgtgtgcacgagtgggagaggggaaagagaaaaaaaggtgatcatggaggaaaaaggtactggataaaagtaaacttcaaaccttagggcgggagcactaaaaccaaaatacatgtattatttatagaaaatattttctgttttaatcttttctttttaaacaaggactcatacttaaaaaaatgtttagcaaaaaaaaaaaaagttgagaacttttaatttattttaaggactgcaaatgccagtgtaattttttaatttgcagtttctgtaaacaacttgtataatagaaaagcagagaaataaatttccctccccttcaagatgcacctcatgtttgttttaaggtatagcatttagtccagatttgagaaagtttggggtgaacaaggtaagaaagatttttttttttttggcatcaaatctttctgcctgcctctcagcttgcttcagaaaatttaaaaaatcacaatagtaatcaaaacatacataacattgaaacagaaggaaatgctgtggaccacagaactccaagaattgtttaaaaaaaaaaaagtgctaccctgagaaaagtactcttaatactcttgaaatctttagagcaactttaaggcttgtaaatacatagaacaaatatttaaaaaaacaaaaagaaattgactcagtactatttcttttcactttgaaaatataaagaacaaaataaagacaaacattgcaagtttaaaagaaagtaaagtgacttctcctttggacagctgctgcatgtgtgcccattcctgggggtgctgtctggctatttattgtctaattcaaatcactcctgaggggagagagataaaacgagagagagtgagagagtgtgtgtatgtgcgtgtatgcgcacgtatgtgcatgcacatgtatgtatgtatat
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:8672 -> Molecular function: GO:0000339 [RNA cap binding] evidence: TAS
            GeneID:8672 -> Molecular function: GO:0003677 [DNA binding] evidence: IEA
            GeneID:8672 -> Molecular function: GO:0003743 [translation initiation factor activity] evidence: IEA
            GeneID:8672 -> Molecular function: GO:0008135 [translation factor activity, nucleic acid binding] evidence: TAS
            GeneID:8672 -> Biological process: GO:0006446 [regulation of translational initiation] evidence: TAS
            GeneID:8672 -> Biological process: GO:0016070 [RNA metabolic process] evidence: IEA
            GeneID:8672 -> Biological process: GO:0019048 [modulation by virus of host morphology or physiology] evidence: IEA
            GeneID:8672 -> Biological process: GO:0019221 [cytokine-mediated signaling pathway] evidence: TAS
            GeneID:8672 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:8672 -> Cellular component: GO:0016281 [eukaryotic translation initiation factor 4F complex] evidence: TAS

by @meso_cacase at DBCLS
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