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2024-04-26 08:42:54, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_003597 4051 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens Kruppel-like factor 11 (KLF11), transcript variant 1,
mRNA.
ACCESSION NM_003597 XM_938887
VERSION NM_003597.4 GI:40548370
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4051)
AUTHORS Fan,Y., Guo,Y., Zhang,J., Subramaniam,M., Song,C.Z., Urrutia,R. and
Chen,Y.E.
TITLE Kruppel-like factor-11, a transcription factor involved in diabetes
mellitus, suppresses endothelial cell activation via the nuclear
factor-kappaB signaling pathway
JOURNAL Arterioscler. Thromb. Vasc. Biol. 32 (12), 2981-2988 (2012)
PUBMED 23042817
REMARK GeneRIF: Kruppel-like factor-11, a transcription factor involved in
diabetes mellitus, suppresses endothelial cell activation via the
nuclear factor-kappaB signaling pathway.
REFERENCE 2 (bases 1 to 4051)
AUTHORS Faryna,M., Konermann,C., Aulmann,S., Bermejo,J.L., Brugger,M.,
Diederichs,S., Rom,J., Weichenhan,D., Claus,R., Rehli,M.,
Schirmacher,P., Sinn,H.P., Plass,C. and Gerhauser,C.
TITLE Genome-wide methylation screen in low-grade breast cancer
identifies novel epigenetically altered genes as potential
biomarkers for tumor diagnosis
JOURNAL FASEB J. 26 (12), 4937-4950 (2012)
PUBMED 22930747
REMARK GeneRIF: Data indicate that median methylation levels of BCAN,
HOXD1, KCTD8, KLF11, NXPH1, POU4F1, SIM1, and TCF7L1 were >/=30%
higher than in normal samples, representing potential biomarkers
for tumor diagnosis.
REFERENCE 3 (bases 1 to 4051)
AUTHORS Perakakis,N., Danassi,D., Alt,M., Tsaroucha,E., Mehana,A.E.,
Rimmer,N., Laubner,K., Wang,H., Wollheim,C.B., Seufert,J. and
Path,G.
TITLE Human Kruppel-like factor 11 differentially regulates human insulin
promoter activity in beta-cells and non-beta-cells via p300 and
PDX1 through the regulatory sites A3 and CACCC box
JOURNAL Mol. Cell. Endocrinol. 363 (1-2), 20-26 (2012)
PUBMED 22801105
REMARK GeneRIF: KLF11 has a role in fine-tuning insulin transcription in
certain cellular situations rather than representing a major
transcriptional activator or repressor of the insulin gene.
REFERENCE 4 (bases 1 to 4051)
AUTHORS Grunewald,M., Johnson,S., Lu,D., Wang,Z., Lomberk,G., Albert,P.R.,
Stockmeier,C.A., Meyer,J.H., Urrutia,R., Miczek,K.A., Austin,M.C.,
Wang,J., Paul,I.A., Woolverton,W.L., Seo,S., Sittman,D.B. and
Ou,X.M.
TITLE Mechanistic role for a novel glucocorticoid-KLF11 (TIEG2) protein
pathway in stress-induced monoamine oxidase A expression
JOURNAL J. Biol. Chem. 287 (29), 24195-24206 (2012)
PUBMED 22628545
REMARK GeneRIF: KLF11 is an MAO A regulator and is produced in response to
neuronal stress, which transcriptionally activates MAO A.
REFERENCE 5 (bases 1 to 4051)
AUTHORS Seo,S., Lomberk,G., Mathison,A., Buttar,N., Podratz,J., Calvo,E.,
Iovanna,J., Brimijoin,S., Windebank,A. and Urrutia,R.
TITLE Kruppel-like factor 11 differentially couples to histone
acetyltransferase and histone methyltransferase chromatin
remodeling pathways to transcriptionally regulate dopamine D2
receptor in neuronal cells
JOURNAL J. Biol. Chem. 287 (16), 12723-12735 (2012)
PUBMED 22375010
REMARK GeneRIF: Here we report the characterization of two antagonistic,
chromatin-mediated mechanisms by which KLF11 regulated the
transcription of the dopamine D2 receptor.
REFERENCE 6 (bases 1 to 4051)
AUTHORS Jia,L., Young,M.F., Powell,J., Yang,L., Ho,N.C., Hotchkiss,R.,
Robey,P.G. and Francomano,C.A.
TITLE Gene expression profile of human bone marrow stromal cells:
high-throughput expressed sequence tag sequencing analysis
JOURNAL Genomics 79 (1), 7-17 (2002)
PUBMED 11827452
REFERENCE 7 (bases 1 to 4051)
AUTHORS Zhang,J.S., Moncrieffe,M.C., Kaczynski,J., Ellenrieder,V.,
Prendergast,F.G. and Urrutia,R.
TITLE A conserved alpha-helical motif mediates the interaction of
Sp1-like transcriptional repressors with the corepressor mSin3A
JOURNAL Mol. Cell. Biol. 21 (15), 5041-5049 (2001)
PUBMED 11438660
REFERENCE 8 (bases 1 to 4051)
AUTHORS Scohy,S., Gabant,P., Van Reeth,T., Hertveldt,V., Dreze,P.L., Van
Vooren,P., Riviere,M., Szpirer,J. and Szpirer,C.
TITLE Identification of KLF13 and KLF14 (SP6), novel members of the
SP/XKLF transcription factor family
JOURNAL Genomics 70 (1), 93-101 (2000)
PUBMED 11087666
REFERENCE 9 (bases 1 to 4051)
AUTHORS Asano,H., Li,X.S. and Stamatoyannopoulos,G.
TITLE FKLF, a novel Kruppel-like factor that activates human embryonic
and fetal beta-like globin genes
JOURNAL Mol. Cell. Biol. 19 (5), 3571-3579 (1999)
PUBMED 10207080
REFERENCE 10 (bases 1 to 4051)
AUTHORS Cook,T., Gebelein,B., Mesa,K., Mladek,A. and Urrutia,R.
TITLE Molecular cloning and characterization of TIEG2 reveals a new
subfamily of transforming growth factor-beta-inducible Sp1-like
zinc finger-encoding genes involved in the regulation of cell
growth
JOURNAL J. Biol. Chem. 273 (40), 25929-25936 (1998)
PUBMED 9748269
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from CB990375.1, AF272830.1,
AI183650.1, BQ881155.1, AK002186.1, BM548792.1 and AI755210.1.
This sequence is a reference standard in the RefSeqGene project.
On or before Mar 4, 2006 this sequence version replaced
gi:88954805, gi:40255017.
Summary: The protein encoded by this gene is a zinc finger
transcription factor that binds to SP1-like sequences in epsilon-
and gamma-globin gene promoters. This binding inhibits cell growth
and causes apoptosis. Defects in this gene are a cause of
maturity-onset diabetes of the young type 7 (MODY7). Three
transcript variants encoding two different isoforms have been found
for this gene. [provided by RefSeq, Apr 2010].
Transcript Variant: This variant (1) encodes the longer isoform
(a).
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC063286.1, AK289816.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025082 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-112 CB990375.1 28-139
113-1346 AF272830.1 87-1320
1347-1876 AF272830.1 1321-1850
1877-2007 AI183650.1 4-134 c
2008-2754 BQ881155.1 36-782
2755-3258 AK002186.1 815-1318
3259-3619 BM548792.1 134-494
3620-4030 AK002186.1 1680-2090
4031-4051 AI755210.1 1-21 c
FEATURES Location/Qualifiers
source 1..4051
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2p25"
gene 1..4051
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/note="Kruppel-like factor 11"
/db_xref="GeneID:8462"
/db_xref="HGNC:11811"
/db_xref="HPRD:04488"
/db_xref="MIM:603301"
exon 1..204
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/inference="alignment:Splign:1.39.8"
variation 68..70
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace=""
/replace="gcc"
/db_xref="dbSNP:372827624"
STS 113..1751
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/db_xref="UniSTS:480520"
STS 131..1734
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/db_xref="UniSTS:482122"
CDS 163..1701
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/note="isoform a is encoded by transcript variant 1;
krueppel-like factor 11; TIEG-2; TGFB-inducible early
growth response protein 2; transforming growth
factor-beta-inducible early growth response protein 2"
/codon_start=1
/product="Krueppel-like factor 11 isoform a"
/protein_id="NP_003588.1"
/db_xref="GI:4507503"
/db_xref="CCDS:CCDS1668.1"
/db_xref="GeneID:8462"
/db_xref="HGNC:11811"
/db_xref="HPRD:04488"
/db_xref="MIM:603301"
/translation="
MHTPDFAGPDDARAVDIMDICESILERKRHDSERSTCSILEQTDMEAVEALVCMSSWGQRSQKGDLLRIRPLTPVSDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVSPQVTDSKACTATDVLQSSAVVARALSGGAERGLLGLEPVPSSPCRAKGTSVIRHTGESPAACFPTIQTPDCRLSDSREGEEQLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGWPGAVQTCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLPAFLKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAAGNTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRIASAESPGSPLVSMPASA
"
misc_feature 1339..>1509
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/note="FOG: Zn-finger [General function prediction only];
Region: COG5048"
/db_xref="CDD:34653"
misc_feature 1390..1473
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/note="Zinc-finger double domain; Region: zf-H2C2_2;
pfam13465"
/db_xref="CDD:205643"
misc_feature 1480..1551
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/note="Zinc-finger double domain; Region: zf-H2C2_2;
pfam13465"
/db_xref="CDD:205643"
misc_feature 1525..1590
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/note="Zinc finger, C2H2 type; Region: zf-C2H2; cl15478"
/db_xref="CDD:210117"
exon 205..474
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/inference="alignment:Splign:1.39.8"
variation 211
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200094318"
variation 214
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:373697732"
variation 230
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:367566983"
variation 243
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:140643007"
variation 248
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:150096859"
variation 252
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:146577005"
variation 255
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:371327904"
variation 303
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:138710480"
STS 318..450
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/standard_name="RH78629"
/db_xref="UniSTS:80550"
variation 339
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:201555141"
variation 347
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:35927125"
variation 364
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:202142040"
variation 381
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:373935239"
variation 387
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:144083374"
variation 403
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200260496"
variation 406
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:76059450"
variation 437
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:146264648"
exon 475..1420
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/inference="alignment:Splign:1.39.8"
variation 475
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace=""
/replace="t"
/db_xref="dbSNP:55653873"
variation 520
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:201792575"
variation 533
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:61755332"
variation 540
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:199941261"
variation 569
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:139111425"
variation 572
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:145933214"
variation 591
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:113903638"
variation 599
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:148968483"
variation 609
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:368067336"
variation 613
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:147735654"
variation 618
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:373126146"
variation 648
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:146462049"
variation 663
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:377399356"
variation 684
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:200997824"
variation 692
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:140504133"
variation 694
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:138601862"
variation 703
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:146238335"
variation 705
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:142659789"
variation 708
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:142266428"
variation 739
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:368982748"
variation 759
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:150737124"
variation 770
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:145588324"
variation 805
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:374436407"
variation complement(821)
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:34336420"
variation 833
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:148922317"
variation 835
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:200061013"
variation 841
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200561467"
variation 851
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:370039403"
variation 859
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:373828519"
variation 864
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:372266786"
variation 919
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:374251576"
variation 924
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:372404632"
variation 944
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:148123124"
variation 968
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:145504876"
variation 973
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:368207952"
variation 983
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:142673414"
variation 1013
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:372404152"
variation 1032
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:149235463"
variation 1038
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:201595721"
variation 1072
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200635526"
variation 1082
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:182304641"
variation 1114
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:377198797"
variation 1115
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:144431930"
variation 1117
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:368577352"
variation 1134
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:143517559"
variation 1136
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:144949098"
variation 1149
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:371589306"
variation 1154
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:151317435"
variation 1156
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:375265808"
variation 1164
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:369681560"
variation 1186
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:373173330"
variation 1201
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:121912645"
variation 1210
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:199649394"
variation 1212
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:145193520"
variation 1220
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:141318309"
variation 1239
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:146486664"
variation 1245
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:371102481"
variation 1258
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="t"
/db_xref="dbSNP:372514890"
variation 1264
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:144897109"
variation 1280
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:141324729"
variation 1282
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:201432055"
variation 1292
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:370236540"
variation 1293
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:137865082"
variation 1295
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:35476458"
variation 1299
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:199624763"
variation 1323
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:117449189"
variation 1347
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="t"
/db_xref="dbSNP:11687357"
variation 1362
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:201561310"
variation 1367
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:34762805"
variation 1408
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:369331650"
exon 1421..4030
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/inference="alignment:Splign:1.39.8"
variation 1472
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:369814305"
variation 1524
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="t"
/db_xref="dbSNP:373796305"
variation 1544
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:199770737"
variation 1555
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:200532025"
variation 1556
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:142970758"
variation 1560
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:374953405"
variation 1591
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:151292984"
variation 1595
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:369974149"
variation 1610
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:201735305"
variation 1664
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:377358836"
variation 1665
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:36091043"
variation 1744
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:75910133"
variation 1748
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:370864119"
variation 1808
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:140559044"
variation 1895
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:76220150"
variation 1917
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:199892235"
variation 1918..1919
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace=""
/replace="t"
/replace="tt"
/db_xref="dbSNP:34206941"
variation 1918
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:201145049"
variation 1919
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:112893539"
variation 1929
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="t"
/db_xref="dbSNP:78254957"
variation 1936
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:150051327"
variation 1942
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:191010106"
variation 1956
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:111703851"
variation 1963
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:147746428"
variation 2112
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:183232432"
variation 2136
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="t"
/db_xref="dbSNP:72786612"
variation 2171
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:370800766"
variation 2245
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:4444493"
variation 2305
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:141123835"
variation 2313
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:187519040"
variation 2342..2357
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace=""
/replace="caatcattcctgtcac"
/db_xref="dbSNP:143993746"
variation 2345..2360
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace=""
/replace="tcattcctgtcaccaa"
/db_xref="dbSNP:367862174"
variation 2355
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:144723641"
variation 2356
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:151031088"
variation 2357
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:140637703"
variation 2439
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:146942100"
variation 2512
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:199832449"
variation 2544
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:191916595"
variation 2583
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:183240123"
variation 2628
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:137999167"
variation 2657
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:149067484"
variation 2681
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:113527829"
variation 2682
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:148235172"
variation 2784..2785
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace=""
/replace="ac"
/db_xref="dbSNP:376210725"
variation 2876
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="t"
/db_xref="dbSNP:141259297"
variation 2961
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:145555745"
polyA_signal 3178..3183
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
polyA_site 3221
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
variation 3259
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:4669522"
variation 3269
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:138161088"
variation 3309
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:142746538"
variation 3326
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:188355532"
variation 3333
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:371202712"
variation 3359
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:367805998"
variation 3426
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:374263399"
variation 3482
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:6722205"
variation 3554
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:7632"
variation 3727
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:146068438"
STS 3747..4003
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/standard_name="A005P43"
/db_xref="UniSTS:22254"
STS 3747..4003
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/standard_name="G20404"
/db_xref="UniSTS:22253"
STS 3757..3868
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/standard_name="RH11597"
/db_xref="UniSTS:10463"
variation 3819
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:192585504"
variation 3845
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:139703378"
variation 3856
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:375562533"
variation 3884
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:14465"
variation 3889
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:14466"
STS 3891..3998
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/standard_name="SHGC-36737"
/db_xref="UniSTS:11113"
variation 3975
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:149368043"
polyA_site 4030
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
ORIGIN
gagggccgcgccggggcagagccgcgcgggcgggcgaggcgcgtgccggccgcaggagctccgggttgccgccgccgccgccgcccgcagcccacgtgcggccgctgctgcgcccgagctcacgccccgcggccgctttgttgctcccggccggcctgcacgatgcacacgccggacttcgcaggcccagacgacgcgcgcgcagttgacatcatggacatatgtgagtccatcctggagaggaagcggcatgacagcgaaaggtctacttgcagcatcttggagcagacagacatggaagctgtcgaggctcttgtttgtatgagctcctggggtcaaagatcccagaaaggtgacctgttgcggataagacccctcacgcctgtctctgactctggggatgtcaccaccactgtgcatatggatgcagccacacctgaactaccaaaagacttccattctttatcgactctgtgcataactcctcctcagagccctgatctcgtggagccatcgacaaggacacctgtttctccccaagtaacagattccaaagcatgtacagccacggatgttctccagtcctctgccgtagtggccagagctctgagcgggggcgcggagaggggcttgctgggtttggagccagtgcccagctctccctgcagggccaaggggactagcgtgatccgacacactggggagagccctgctgcctgctttcccaccatccagactccagattgccggctttctgacagcagagaaggagaagagcagcttctgggacactttgaaactttgcaggacacacacctcacggacagtttactcagcactaacttggtgtcctgtcagccctgcttgcacaagtctggtggcctgctgctcactgacaaaggccagcaggcagggtggcctggtgcagttcagacttgctcaccaaagaattatgaaaatgacctgcccaggaaaaccacccctctgatttctgtctctgtccctgctccccctgtcctttgccagatgatccctgtgactggacaaagtagcatgttaccagcttttttgaagccccctccccagttgtctgtggggactgtgagacccatcctagctcaggctgctccagcgcctcaacctgtgttcgtgggacctgctgtgcctcagggagctgtgatgttggtcctgccccagggagccctccctccgcctgccccctgtgcagccaatgtcatggctgccgggaataccaagttgttgccccttgcccctgctccagtgttcatcacctctagccaaaactgtgtccctcaggtagacttttcccgaaggaggaactatgtttgcagcttcccaggttgccggaagacctacttcaaaagttcccaccttaaggcccatcttcgcactcacacaggggagaagcctttcaactgcagctgggatggctgtgataaaaagtttgctcgttcggatgagctgtcacgccaccgcagaactcacacaggggagaagaagtttgtgtgcccggtgtgtgaccgacgtttcatgcgcagtgaccacctgacgaagcatgcccggcgccacatgacgaccaagaagatcccaggctggcaggcagaggttggcaagctgaacagaatcgcctctgcagagagcccggggagcccactggtgagcatgccagcctctgcctgaaaggtccattaggacatcactcatgggatttttaaaaagcctctttccaggaatggaactgatggattcctctcccactgcctcacccaaaaaaaacggtcttggcggcctaggggaagatcggggagctggttttgatgaaagtatgttaacttttcttttccacttgggaccctgttcagtatcttttgtagtttcagaagtttttttgttttggttttttttttaaagaaatggtagaaaatttgataatctgaatcaccagcattcaaacaaatatttcggcaataaagtttacaaaatctggatttttacaaccttttctattgatgttttgtagaaataagacagggtactaatttttatactggtttttagaaaaatatttatattgttggtgctcaaatcaccaatttctagctagatcattttgcagccttcttttcagtgtttaataacaaagtttttcctaatggcccttcttttagtaaactggacatgttattccactacaaaaaccacaagttatctggccttttagatctttttggaatcggacctggttgagtaaggacctcttaaaagggaaaaataaattttgccgtcagcttcttcataacgttttcaaggaaattctaggcaatcattcctgtcaccaaagaactaaaattttggttgactggaactagtgagctgtgtccatggtgtgtcatgaaggatgtaccccagagagtaacatgagccactgggcagatcccagggaccagtacttgctgcaggatctagtctgtaatagtcttggccatggctctgctgaaagcaagccattcagtttcttgtttgtacctaaaacaccaaaaaagaaacactcaaatccagctgctttgtcaattgtcagttctgactccttttgctgtggccttatccgtactatattgtgggtagagtaacttctcagaaaaaaaggaaatgtctgtattggttggatgaaactccaccagagcacagcttagctggggcgagatgcatgtgaaggcaggcagtgccaagattccgcttcctttgtttgccaaatactagaaacacaaggaaatgcaagttacgctaaatggcagtaatactacccaactgcctttctgttcattttgtttgaaggaaattgttttgaccaaacagaaaattacttggaatggtgtgttttacagtctacctagaaaatagatggacaatatttttcaactgtatgagcacgtagataaccgagagaatgtggccacctgtgttcaagaagccactgatactggtttttgttaaacattggaagttcaggcaatggaataaatgtaggaacatacagaatgttgcactaatttggtagcctgggaattttttttattgtgcagtatgtatttaaattttgtctatgttaattaccagcatttacctttatttaaatgatggtaaggtggaatattgaataaaattaggttttgtgttttgttctttgtagtctgataaaatctccacctggtcattcattgtgtgtgacttgatacctgttaacttgccccttagtatcagctgttacttgacacaaatgtgtgtgttattcagaggttttcagtctggacactccataggtgagtgtcgtgtcttcgtgagacagcacagttgtctcatgttgtgcatagttcatgtttcctcaccacccagtcctttctcctgctcatcaaaatcagcatacacatttttgactgtacacactataaatggcatcaaatttggatatttttcttaattatgacatgcaaagtaatgtgagtcctgccagtattctggtggataaggtcttttgagtatttggttgcttgtcacaacattctccaagcagtgatatttctaaagaggagatacatgttgaaaacggttttaatttacacttccatttcctgattacatttggaaatactttgtgtaaaccatcccccttccacctccatttgtctgttgaaagattttaagttggaaacagttcctgtctgaaaactcttctgagaaccacaaaccttgtgtatggattcggcatggagccctcagctggcggctctgggtgctgacggccgctggagaggtgggctcccctcgtgcactttattgcctgggcagttttgcttgatcttttgtgactttgagccttttaagtagtttgaatgataagacttaaaatgtttcataattatgttttatgtaacagactttgacattatttaaacgagcatgtgtaatgtaacttttctctttgaatcatataaaacttgattttacattgaaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:8462 -> Molecular function: GO:0000981 [sequence-specific DNA binding RNA polymerase II transcription factor activity] evidence: IDA
GeneID:8462 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: TAS
GeneID:8462 -> Molecular function: GO:0044212 [transcription regulatory region DNA binding] evidence: IDA
GeneID:8462 -> Molecular function: GO:0046872 [metal ion binding] evidence: IEA
GeneID:8462 -> Biological process: GO:0000115 [regulation of transcription involved in S phase of mitotic cell cycle] evidence: IDA
GeneID:8462 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IDA
GeneID:8462 -> Biological process: GO:0006366 [transcription from RNA polymerase II promoter] evidence: TAS
GeneID:8462 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:8462 -> Biological process: GO:0008285 [negative regulation of cell proliferation] evidence: IDA
GeneID:8462 -> Biological process: GO:0043065 [positive regulation of apoptotic process] evidence: IDA
GeneID:8462 -> Cellular component: GO:0005634 [nucleus] evidence: IEA
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