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2024-04-19 18:55:45, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_003468 6584 bp mRNA linear PRI 15-JUL-2013
DEFINITION Homo sapiens frizzled family receptor 5 (FZD5), mRNA.
ACCESSION NM_003468
VERSION NM_003468.3 GI:111160871
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6584)
AUTHORS Liu,Y., Chen,S.H., Jin,X. and Li,Y.M.
TITLE Analysis of differentially expressed genes and microRNAs in
alcoholic liver disease
JOURNAL Int. J. Mol. Med. 31 (3), 547-554 (2013)
PUBMED 23337955
REMARK GeneRIF: FZD5 was downregulated and reduced the synthesis of
membrane transport protein in the hepatic membrane and the membrane
stability, and accelerated the liver cell apoptosis process in
alcoholic liver disease.
REFERENCE 2 (bases 1 to 6584)
AUTHORS Thiele,S., Rauner,M., Goettsch,C., Rachner,T.D., Benad,P.,
Fuessel,S., Erdmann,K., Hamann,C., Baretton,G.B., Wirth,M.P.,
Jakob,F. and Hofbauer,L.C.
TITLE Expression profile of WNT molecules in prostate cancer and its
regulation by aminobisphosphonates
JOURNAL J. Cell. Biochem. 112 (6), 1593-1600 (2011)
PUBMED 21344486
REMARK GeneRIF: Several members of the WNT pathway, including WNT5A, FZD5,
and DKK1 were highly up-regulated in PCa tissue from patients with
advanced PCa.
REFERENCE 3 (bases 1 to 6584)
AUTHORS Moller,M., Nebel,A., van Helden,P.D., Schreiber,S. and Hoal,E.G.
TITLE Analysis of eight genes modulating interferon gamma and human
genetic susceptibility to tuberculosis: a case-control association
study
JOURNAL BMC Infect. Dis. 10, 154 (2010)
PUBMED 20525402
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
Publication Status: Online-Only
REFERENCE 4 (bases 1 to 6584)
AUTHORS Terabayashi,T., Funato,Y., Fukuda,M. and Miki,H.
TITLE A coated vesicle-associated kinase of 104 kDa (CVAK104) induces
lysosomal degradation of frizzled 5 (Fzd5)
JOURNAL J. Biol. Chem. 284 (39), 26716-26724 (2009)
PUBMED 19643732
REMARK GeneRIF: Studies identify CVAK104 as a novel binding partner of
Dishevelled (Dvl) and that CVAK104 also interacts with Fzd5.
REFERENCE 5 (bases 1 to 6584)
AUTHORS Kim,J.G., Kim,H., Jee,B.C., Suh,C.S., Choi,Y.M. and Moon,S.Y.
TITLE Non-association between polymorphisms of the frizzled receptor
genes and bone mineral density in postmenopausal Korean women
JOURNAL J. Korean Med. Sci. 24 (3), 443-447 (2009)
PUBMED 19543507
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 6 (bases 1 to 6584)
AUTHORS Medina,A. and Steinbeisser,H.
TITLE Interaction of Frizzled 7 and Dishevelled in Xenopus
JOURNAL Dev. Dyn. 218 (4), 671-680 (2000)
PUBMED 10906785
REFERENCE 7 (bases 1 to 6584)
AUTHORS Tanaka,S., Akiyoshi,T., Mori,M., Wands,J.R. and Sugimachi,K.
TITLE A novel frizzled gene identified in human esophageal carcinoma
mediates APC/beta-catenin signals
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 95 (17), 10164-10169 (1998)
PUBMED 9707618
REFERENCE 8 (bases 1 to 6584)
AUTHORS Finch,P.W., He,X., Kelley,M.J., Uren,A., Schaudies,R.P.,
Popescu,N.C., Rudikoff,S., Aaronson,S.A., Varmus,H.E. and
Rubin,J.S.
TITLE Purification and molecular cloning of a secreted, Frizzled-related
antagonist of Wnt action
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 94 (13), 6770-6775 (1997)
PUBMED 9192640
REFERENCE 9 (bases 1 to 6584)
AUTHORS He,X., Saint-Jeannet,J.P., Wang,Y., Nathans,J., Dawid,I. and
Varmus,H.
TITLE A member of the Frizzled protein family mediating axis induction by
Wnt-5A
JOURNAL Science 275 (5306), 1652-1654 (1997)
PUBMED 9054360
REFERENCE 10 (bases 1 to 6584)
AUTHORS Wang,Y., Macke,J.P., Abella,B.S., Andreasson,K., Worley,P.,
Gilbert,D.J., Copeland,N.G., Jenkins,N.A. and Nathans,J.
TITLE A large family of putative transmembrane receptors homologous to
the product of the Drosophila tissue polarity gene frizzled
JOURNAL J. Biol. Chem. 271 (8), 4468-4476 (1996)
PUBMED 8626800
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BF059357.1, AB043702.1,
AC096772.3, AK024850.1 and AK000125.1.
On Aug 4, 2006 this sequence version replaced gi:27894384.
Summary: Members of the 'frizzled' gene family encode
7-transmembrane domain proteins that are receptors for Wnt
signaling proteins. The FZD5 protein is believed to be the
receptor for the Wnt5A ligand. [provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AB043702.1, U43318.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025084 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-25 BF059357.1 463-487 c
26-460 AB043702.1 1-435
461-461 AC096772.3 89737-89737 c
462-757 AB043702.1 437-732
758-758 AC096772.3 89440-89440 c
759-2595 AB043702.1 734-2570
2596-4089 AC096772.3 86109-87602 c
4090-6552 AK024850.1 1-2463
6553-6584 AK000125.1 1756-1787
FEATURES Location/Qualifiers
source 1..6584
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2q33.3"
gene 1..6584
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/note="frizzled family receptor 5"
/db_xref="GeneID:7855"
/db_xref="HGNC:4043"
/db_xref="MIM:601723"
exon 1..155
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/inference="alignment:Splign:1.39.8"
variation 147
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/replace="g"
/replace="t"
/db_xref="dbSNP:1134843"
exon 156..6564
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/inference="alignment:Splign:1.39.8"
variation 247
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/replace="a"
/replace="g"
/db_xref="dbSNP:55717133"
misc_feature 276..278
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/note="upstream in-frame stop codon"
CDS 411..2168
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/note="frizzled 5, seven transmembrane spanning receptor;
seven-transmembrane receptor frizzled-5; Wnt receptor;
fz-5; fzE5"
/codon_start=1
/product="frizzled-5 precursor"
/protein_id="NP_003459.2"
/db_xref="GI:27894385"
/db_xref="CCDS:CCDS33366.1"
/db_xref="GeneID:7855"
/db_xref="HGNC:4043"
/db_xref="MIM:601723"
/translation="
MARPDPSAPPSLLLLLLAQLVGRAAAASKAPVCQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGRDAEVLCMDYNRSEATTAPPRPFPAKPTLPGPPGAPASGGECPAGGPFVCKCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSFSADERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSREHNHIHYETTGPALCTIVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYEQHYRESWEAALTCACPGHDTGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTVESWRRFTSRCCCRPRRGHKSGGAMAAGDYPEASAALTGRTGPPGPAATYHKQVSLSHV
"
sig_peptide 411..488
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/inference="COORDINATES: ab initio prediction:SignalP:4.0"
mat_peptide 489..2165
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/product="frizzled-5"
misc_feature 495..878
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/note="Cysteine-rich Wnt-binding domain (CRD) of the
frizzled 5 (Fz5) receptor.proteins; Region: CRD_FZ5;
cd07460"
/db_xref="CDD:143569"
misc_feature order(528..530,534..542,546..554)
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/note="putative Wnt binding site [polypeptide binding];
other site"
/db_xref="CDD:143569"
misc_feature 1083..2030
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/note="Frizzled/Smoothened family membrane region; Region:
Frizzled; pfam01534"
/db_xref="CDD:144942"
misc_feature 1125..1187
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q13467.2);
transmembrane region"
misc_feature 1221..1283
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q13467.2);
transmembrane region"
misc_feature 1356..1418
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q13467.2);
transmembrane region"
misc_feature 1485..1547
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q13467.2);
transmembrane region"
misc_feature 1617..1679
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q13467.2);
transmembrane region"
misc_feature 1758..1820
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q13467.2);
transmembrane region"
misc_feature 1911..1973
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q13467.2);
transmembrane region"
misc_feature 1983..2000
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q13467.2);
Region: Lys-Thr-X-X-X-Trp motif, mediates interaction with
the PDZ domain of Dvl family members (By similarity)"
misc_feature 2157..2165
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q13467.2);
Region: PDZ-binding"
variation 672
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/replace="a"
/replace="t"
/db_xref="dbSNP:1056614"
STS 1025..1153
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/standard_name="FZD5"
/db_xref="UniSTS:278455"
STS 1932..2167
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/standard_name="PMC16008P2"
/db_xref="UniSTS:271447"
STS 2156..2368
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/standard_name="STS-U43318"
/db_xref="UniSTS:57300"
polyA_site 2529
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
variation 3050
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/replace="c"
/replace="t"
/db_xref="dbSNP:201741699"
STS 6313..6558
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
/standard_name="STS-T95625"
/db_xref="UniSTS:52811"
polyA_signal 6525..6530
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
polyA_signal 6545..6550
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
polyA_site 6546
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
polyA_site 6552
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
polyA_site 6564
/gene="FZD5"
/gene_synonym="C2orf31; HFZ5"
ORIGIN
tgctgccatgtgccgctgccacgggtacccagcctgtcgctaaactttccgggcgccagcccggctctgagtcgcgcttctcagcggagtgacccagggacggaggacccaggctggctggggactgtctgctcttctcggcgggatccgtggagagtcctttccctggaatccgagccctaaccgtctctccccagccctatccggcgaggagcggagcgctgccagcggaggcagcgccttcccgaagcagtttatctttggacggttttctttaaaggaaaaagcaaccaacaggttgccagccccggcgccacacacgagacgccggagggagaagccccggcccggattcctctgcctgtgtgcgtccctcgcgggctgctggaggcgaggggagggagggggcgatggctcggcctgacccatccgcgccgccctcgctgttgctgctgctcctagcgcagctggtgggccgggcggccgccgcgtccaaggccccggtgtgccaggaaatcacggtgcccatgtgccgcggcatcggctacaacctgacgcacatgcccaaccagttcaaccacgacacgcaggacgaggcgggcctggaggtgcaccagttctggccgctggtggagatccaatgctcgccggacctgcgcttcttcctatgctctatgtacacgcccatctgtctgcccgactaccacaagccgctgccgccctgccgctcggtgtgcgagcgcgccaaggccggctgctcgccgctgatgcgccagtacggcttcgcctggcccgagcgcatgagctgcgaccgcctcccggtgctgggccgcgacgccgaggtcctctgcatggattacaaccgcagcgaggccaccacggcgccccccaggcctttcccagccaagcccacccttccaggcccgccaggggcgccggcctcggggggcgaatgccccgctgggggcccgttcgtgtgcaagtgtcgcgagcccttcgtgcccattctgaaggagtcacacccgctctacaacaaggtgcggacgggccaggtgcccaactgcgcggtaccctgctaccagccgtccttcagtgccgacgagcgcacgttcgccaccttctggataggcctgtggtcggtgctgtgcttcatctccacgtccaccacagtggccaccttcctcatcgacatggaacgcttccgctatcctgagcgccccatcatcttcctgtcagcctgctacctgtgcgtgtcgctgggcttcctggtgcgtctggtcgtgggccatgccagcgtggcctgcagccgcgagcacaaccacatccactacgagaccacgggccctgcactgtgcaccatcgtcttcctcctggtctacttcttcggcatggccagctccatctggtgggtcatcctgtcgctcacctggttcctggccgccggcatgaagtggggcaacgaggccatcgcgggctacgcgcagtacttccacctggctgcgtggctcatccccagcgtcaagtccatcacggcactggcgctgagctccgtggacggggacccagtggccggcatctgctacgtgggcaaccagaacctgaactcgctgcgcggcttcgtgctgggcccgctggtgctctacctgctggtgggcacgctcttcctgctggcgggcttcgtgtcgctcttccgcatccgcagcgtcatcaagcagggcggcaccaagacggacaagctggagaagctcatgatccgcatcggcatcttcacgctgctctacacggtccccgccagcattgtggtggcctgctacctgtacgagcagcactaccgcgagagctgggaggcggcgctcacctgcgcctgcccgggccacgacaccggccagccgcgcgccaagcccgagtactgggtgctcatgctcaagtacttcatgtgcctggtggtgggcatcacgtcgggcgtctggatctggtcgggcaagacggtggagtcgtggcggcgtttcaccagccgctgctgctgccgcccgcggcgcggccacaagagcgggggcgccatggccgcaggggactaccccgaggcgagcgccgcgctcacaggcaggaccgggccgccgggccccgccgccacctaccacaagcaggtgtccctgtcgcacgtgtaggaggctgccgccgagggactcggccggagagctgaggggaggggggcgttttgtttggtagttttgccaaggtcacttccgtttaccttcatggtgctgttgccccctcccgcggcgacttggagagagggaagaggggcgttttcgaggaagaacctgtcccaggtcttctccaaggggcccagctcacgtgtattctattttgcgtttcttactgccttctttatgggaaccctctttttaatttatatgtatttttcttaatttgtaactttgttgcattttggcaacaatttacctttgctttgggggctttacaatcctaaggttggcgttgtaatgaagttccacttggttcaggtttctttgaactgtgtggtctcaattgggaaaatatatttcctatacgtgtgtctttaaaaaaaaatgtgaacagtgaacgtttcggttgctgtgactgggaagttgttgggtgtgctttttcagccagcttctccttccactgcttaaagtgtccatgattctttaaggtgagctgcagtttatagccccaggtcatacctaggaggggagcataatgagctcagggcctccccaaagtgacaaggttagggagtgcttagcggttttgtgttcagccttagctttgtttatagagggaggttcagtttcttttctgtagtgcttgtaataattctcactcctaacagcaccatcgttgtgtcttgaataagttagaggtagcattatagaggatctggcataaatatttgcagtagtgagagcctaagcgatggtgattggtggagcttgaattttaggctggtgagatggcagctttgtgcctgagaggtagtgggtggttcttaagcttcagtgatcccctttttttttttttttttttttttttaaggaacttgtgttataattttggtaaaagtataaacccactccctctggacaatacttagcgacagttgctaaagggggctcctttttaaatgtaaggactgaaatggatatacttctaataagtaaatttccaacacttatttgctccaccccctcccccctcccccctccccctttatcatgttaaacagcctttttgcttttcttattcctcctctcctggagagctgtgattagaaaccacacccacccttgaatgaagtgcttgaactgggggagggaggctggctacctgtgaacaaacattggcccaaataagggaaaataagtgttcctggactttggactagtttatagccagatattccaagagcagcaagacgttgctctctgccgtctctgaaaacaaaagagatgcataacatgcttgcacaaccttttaaaatatagatcagtatagtgctacctctatagttttcttcctcttctgagaaagcctgtatattgatgatcacacacacacacactttgcaattagagaatttggtttgctttactaatctgtttaactattccttcattcattatgaacgcttatattgatgaacatacacacagaggtttctttgctattagaaaattctgtttgctttcctaatctgtttaagcattcattcatgaagagtgtggggccattactggggaaggggggtgacagtgcctcagccagcaaaataccaatgaccaggattggggactaaatttaggaagctaaaatggccagagcaattaacatttgagaaaatcctgtctaggaaaacaacttgagtgtaggcatttgtaattcacttataccaaagttggaaaagtaaaatttaagcctaggacaatttttacttcatggatgttaaatagacaaatgcatagttcccagggggaatttaaacactttactggtgggaagaaacctagtattaaagttgtaaggactctcaaaaacttcacatttattaaaatgcactgctcttacccaatttatcctctgaattaaaatttcagtggattctacaaaacctcgtacaaatagctacagaactttgtgcctattttattcctctatttattcttctaggaagaagcctcttcctagaatcttgaaatagatcccttgactgaatgccaattcctctcctgtttttcaaatgagagaaccttttctgatcaccttgaccttttccctcatttcatatgtcttcccagaaagtagacagactgctctgctgccttcagtcattgtgcctcatttgggttgtccctccttctttgtggagaaatctggaaatgatgcacagtgtatccaaaagttgtgggatgaagtggatgaaagtgatttaattcatttttagaatttttttttgttttgttttagcaacatgctgaacaactaatttactttaaaaataagccagttaaaacaaaggacgctaagcccaagtggggggcaatattagtcaggatctttggggtctaattccagaccaactttcagaagcacttctttgtctctgttctcacctctgctgtccctctcttccctcatcccctaagagagacaaagataaaagcccacctgcatccctaagtcttactgagatcagccaccccaggggagagaaactggatctacttacagccaccccctgtttccatccatatacttacttcccccaatttgcatgtgattatggaaacaagtcatgctcatgaaagcaactgtaaaataaaaggttatggagtagttcagcaacttcttcacagccagctttgtggagctggggaggacttagggcccattggagtctcttatgtgtacagcttcagggctgtccctttcagtttgattttaagcaatgcctcacttcatagcttagggggtaaggattccattcaggtaggttgtctaaaggaactaatgggacctctcagtgaattagctgaccagattttaggaaatctttttaatttctatgattttccttctcacattttgaaatggtaaaattgactggaaataatttttcttggtgccttattggttttccttgcaaacctttctcatattttctcatgaccattgccagtgaccaaggcccatgtgtgtgttgtgtgtaattgtgggcatgtacaagcttaaataacgtgccgacagcactgtttcaaagttggtattcattaggctgttgcctcctgggctggagctgcgctaatcctgacaccggctgccaggagaaaacctcatggatcacacaccaaaccttaataacagcatccgtgacctgcactctccagtacagaatgggaaccccagagctaggaaatgtagttgtatattttaatgaactgctaccccagccaaagaagcttctttcacttttgtgctctacagaaagcccaaggggggtaggagggacagagctttgaataactgctttctaacactaaatgtggccaacaggacagagcacatcacacgtataggcaggtgtgagggacagtggctaagaattgcctgctccctctgcatgctctttcttgtttccaaagtccaatcaagtgatcctgggaaacaaatctgtctggattgcggagggtggttctgaaagaactgccaagacgttaaagaagggtgaagagtaggcagaatataagtagctaacctgagtcaagactctcaaaagctagcagcctgatgacaataggatttatttcagccaggatagtgtctgtctgtgagtgcatcattttaagacagtatgacttcatgttgttacaaactatgtatagtatgtatgttttgtgggttgtatatatacataatatatattatatatatatatgagagatttggtgacttttgatacgggtttggtgcaggtgaatttattactgagccaaatgaggcacataccgagtcagtagttgaagtccagggcattcgatactgtttatgatttccatatatgtatagtgcctatcccatgctgtagtcactgttatgttaaatccagaagttacactagagccagcgatactttatttgtagacaatcaatttgaatccatatgttattactggcagatgatacatgattacagttctgaatctgtaacacttacaaaaggaaacccagagcagcttgatgagtttttgtttctgcttcgttcctgggagtcagtagaaacagcagttgtatgtggttatgttagtctcaagatacttaatttgttgaccttacttcagaaaaattttgtatgtattatatttgtgggaaggtaaaataatcatttgagatttttatcaaatatgaagattagttatttatgaaaaacaaagaaatgtctatttttctttgttcccaattaatgtagataaattttaaaatgcattaaagtaatggtaaagacaataaaaagatgctgtagaaaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:7855 -> Molecular function: GO:0004930 [G-protein coupled receptor activity] evidence: IEA
GeneID:7855 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:7855 -> Molecular function: GO:0017147 [Wnt-protein binding] evidence: IPI
GeneID:7855 -> Molecular function: GO:0019901 [protein kinase binding] evidence: IPI
GeneID:7855 -> Molecular function: GO:0030165 [PDZ domain binding] evidence: IBA
GeneID:7855 -> Molecular function: GO:0031625 [ubiquitin protein ligase binding] evidence: IPI
GeneID:7855 -> Molecular function: GO:0042813 [Wnt-activated receptor activity] evidence: IBA
GeneID:7855 -> Molecular function: GO:0042813 [Wnt-activated receptor activity] evidence: IC
GeneID:7855 -> Biological process: GO:0000578 [embryonic axis specification] evidence: IDA
GeneID:7855 -> Biological process: GO:0001525 [angiogenesis] evidence: IBA
GeneID:7855 -> Biological process: GO:0006915 [apoptotic process] evidence: IBA
GeneID:7855 -> Biological process: GO:0007409 [axonogenesis] evidence: IBA
GeneID:7855 -> Biological process: GO:0007420 [brain development] evidence: IBA
GeneID:7855 -> Biological process: GO:0008285 [negative regulation of cell proliferation] evidence: IEA
GeneID:7855 -> Biological process: GO:0008406 [gonad development] evidence: IBA
GeneID:7855 -> Biological process: GO:0008595 [anterior/posterior axis specification, embryo] evidence: IDA
GeneID:7855 -> Biological process: GO:0030182 [neuron differentiation] evidence: ISS
GeneID:7855 -> Biological process: GO:0031076 [embryonic camera-type eye development] evidence: IBA
GeneID:7855 -> Biological process: GO:0031077 [post-embryonic camera-type eye development] evidence: IBA
GeneID:7855 -> Biological process: GO:0032729 [positive regulation of interferon-gamma production] evidence: IMP
GeneID:7855 -> Biological process: GO:0033077 [T cell differentiation in thymus] evidence: IBA
GeneID:7855 -> Biological process: GO:0043507 [positive regulation of JUN kinase activity] evidence: IEA
GeneID:7855 -> Biological process: GO:0044332 [Wnt receptor signaling pathway involved in dorsal/ventral axis specification] evidence: IDA
GeneID:7855 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IDA
GeneID:7855 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IGI
GeneID:7855 -> Biological process: GO:0048469 [cell maturation] evidence: IEA
GeneID:7855 -> Biological process: GO:0060061 [Spemann organizer formation] evidence: IDA
GeneID:7855 -> Biological process: GO:0060070 [canonical Wnt receptor signaling pathway] evidence: IDA
GeneID:7855 -> Biological process: GO:0060070 [canonical Wnt receptor signaling pathway] evidence: IMP
GeneID:7855 -> Biological process: GO:0060561 [apoptotic process involved in morphogenesis] evidence: IEA
GeneID:7855 -> Biological process: GO:0060716 [labyrinthine layer blood vessel development] evidence: IBA
GeneID:7855 -> Biological process: GO:0071219 [cellular response to molecule of bacterial origin] evidence: IDA
GeneID:7855 -> Cellular component: GO:0000139 [Golgi membrane] evidence: IEA
GeneID:7855 -> Cellular component: GO:0005737 [cytoplasm] evidence: IBA
GeneID:7855 -> Cellular component: GO:0005886 [plasma membrane] evidence: IBA
GeneID:7855 -> Cellular component: GO:0005886 [plasma membrane] evidence: TAS
GeneID:7855 -> Cellular component: GO:0009986 [cell surface] evidence: IDA
GeneID:7855 -> Cellular component: GO:0016021 [integral to membrane] evidence: IEA
GeneID:7855 -> Cellular component: GO:0042995 [cell projection] evidence: IBA
GeneID:7855 -> Cellular component: GO:0048471 [perinuclear region of cytoplasm] evidence: IEA
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DBCLS
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