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2024-04-26 08:23:52, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_003333 2801 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens ubiquitin A-52 residue ribosomal protein fusion
product 1 (UBA52), transcript variant 2, mRNA.
ACCESSION NM_003333
VERSION NM_003333.3 GI:77539056
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2801)
AUTHORS Memet,S.
TITLE NF-kappaB functions in the nervous system: from development to
disease
JOURNAL Biochem. Pharmacol. 72 (9), 1180-1195 (2006)
PUBMED 16997282
REMARK Review article
REFERENCE 2 (bases 1 to 2801)
AUTHORS Wang,A.G., Yoon,S.Y., Oh,J.H., Jeon,Y.J., Kim,M., Kim,J.M.,
Byun,S.S., Yang,J.O., Kim,J.H., Kim,D.G., Yeom,Y.I., Yoo,H.S.,
Kim,Y.S. and Kim,N.S.
TITLE Identification of intrahepatic cholangiocarcinoma related genes by
comparison with normal liver tissues using expressed sequence tags
JOURNAL Biochem. Biophys. Res. Commun. 345 (3), 1022-1032 (2006)
PUBMED 16712791
REFERENCE 3 (bases 1 to 2801)
AUTHORS Foster,L.J., Rudich,A., Talior,I., Patel,N., Huang,X.,
Furtado,L.M., Bilan,P.J., Mann,M. and Klip,A.
TITLE Insulin-dependent interactions of proteins with GLUT4 revealed
through stable isotope labeling by amino acids in cell culture
(SILAC)
JOURNAL J. Proteome Res. 5 (1), 64-75 (2006)
PUBMED 16396496
REFERENCE 4 (bases 1 to 2801)
AUTHORS Hu,Y., Malone,J.P., Fagan,A.M., Townsend,R.R. and Holtzman,D.M.
TITLE Comparative proteomic analysis of intra- and interindividual
variation in human cerebrospinal fluid
JOURNAL Mol. Cell Proteomics 4 (12), 2000-2009 (2005)
PUBMED 16199891
REFERENCE 5 (bases 1 to 2801)
AUTHORS Westhoff,B., Chapple,J.P., van der Spuy,J., Hohfeld,J. and
Cheetham,M.E.
TITLE HSJ1 is a neuronal shuttling factor for the sorting of chaperone
clients to the proteasome
JOURNAL Curr. Biol. 15 (11), 1058-1064 (2005)
PUBMED 15936278
REFERENCE 6 (bases 1 to 2801)
AUTHORS Cross,S.H., Charlton,J.A., Nan,X. and Bird,A.P.
TITLE Purification of CpG islands using a methylated DNA binding column
JOURNAL Nat. Genet. 6 (3), 236-244 (1994)
PUBMED 8012384
REFERENCE 7 (bases 1 to 2801)
AUTHORS Baker,R.T. and Board,P.G.
TITLE The human ubiquitin/52-residue ribosomal protein fusion gene
subfamily (UbA52) is composed primarily of processed pseudogenes
JOURNAL Genomics 14 (2), 520-522 (1992)
PUBMED 1330885
REFERENCE 8 (bases 1 to 2801)
AUTHORS Baker,R.T. and Board,P.G.
TITLE The human ubiquitin-52 amino acid fusion protein gene shares
several structural features with mammalian ribosomal protein genes
JOURNAL Nucleic Acids Res. 19 (5), 1035-1040 (1991)
PUBMED 1850507
REFERENCE 9 (bases 1 to 2801)
AUTHORS Monia,B.P., Ecker,D.J., Jonnalagadda,S., Marsh,J., Gotlib,L.,
Butt,T.R. and Crooke,S.T.
TITLE Gene synthesis, expression, and processing of human ubiquitin
carboxyl extension proteins
JOURNAL J. Biol. Chem. 264 (7), 4093-4103 (1989)
PUBMED 2537304
REFERENCE 10 (bases 1 to 2801)
AUTHORS Salvesen,G., Lloyd,C. and Farley,D.
TITLE cDNA encoding a human homolog of yeast ubiquitin 1
JOURNAL Nucleic Acids Res. 15 (13), 5485 (1987)
PUBMED 3037496
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff in
collaboration with Francesco Amaldi. The reference sequence was
derived from BQ428688.1, AF348700.1, BQ428515.1, AF545864.1 and
BU677484.1.
On Oct 11, 2005 this sequence version replaced gi:15451941.
Summary: Ubiquitin is a highly conserved nuclear and cytoplasmic
protein that has a major role in targeting cellular proteins for
degradation by the 26S proteosome. It is also involved in the
maintenance of chromatin structure, the regulation of gene
expression, and the stress response. Ubiquitin is synthesized as a
precursor protein consisting of either polyubiquitin chains or a
single ubiquitin moiety fused to an unrelated protein. This gene
encodes a fusion protein consisting of ubiquitin at the N terminus
and ribosomal protein L40 at the C terminus, a C-terminal extension
protein (CEP). Multiple processed pseudogenes derived from this
gene are present in the genome. [provided by RefSeq, Jul 2008].
Transcript Variant: This predominant variant (2) uses an alternate
splice site in the 5' UTR, compared to variant 1. Variants 1 and 2
encode the same protein.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BU181957.1, CD246441.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025082 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: full length.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-157 BQ428688.1 5-161
158-561 AF348700.1 107-510
562-771 BQ428515.1 493-702
772-2788 AF545864.1 1-2017
2789-2801 BU677484.1 6-18 c
FEATURES Location/Qualifiers
source 1..2801
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19p13.1-p12"
gene 1..2801
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/note="ubiquitin A-52 residue ribosomal protein fusion
product 1"
/db_xref="GeneID:7311"
/db_xref="HGNC:12458"
/db_xref="HPRD:08931"
/db_xref="MIM:191321"
exon 1..84
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/inference="alignment:Splign:1.39.8"
misc_feature 1
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/note="5'-most of multiple alternative transcription
initiation sites"
variation 4
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:150330486"
variation 15
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="c"
/db_xref="dbSNP:374240046"
misc_feature 54
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/note="predominant transcription initiation site"
STS 57..540
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/db_xref="UniSTS:489012"
variation 59
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:41292105"
variation 83
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="t"
/db_xref="dbSNP:57151456"
exon 85..195
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/inference="alignment:Splign:1.39.8"
variation 86
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:150652049"
CDS 93..479
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/note="ubiquitin-52 amino acid fusion protein; ubiquitin
carboxyl extension protein 52; 60S ribosomal protein L40;
ubiquitin-CEP52; ubiquitin-60S ribosomal protein L40"
/codon_start=1
/product="ubiquitin-60S ribosomal protein L40 precursor"
/protein_id="NP_003324.1"
/db_xref="GI:4507761"
/db_xref="CCDS:CCDS12382.1"
/db_xref="GeneID:7311"
/db_xref="HGNC:12458"
/db_xref="HPRD:08931"
/db_xref="MIM:191321"
/translation="
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK
"
misc_feature 93..320
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/note="Ubiquitin; Region: Ubiquitin; cd01803"
/db_xref="CDD:176398"
mat_peptide 93..320
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/product="ubiquitin"
misc_feature 93..308
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/note="Ubiquitin homologues; Region: UBQ; smart00213"
/db_xref="CDD:214563"
misc_feature order(108..122,210..212,216..218,222..224,231..239,
294..296,300..320)
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/note="Ubq - E2 interaction site; other site"
/db_xref="CDD:176398"
misc_feature order(108..110,114..122,207..209,213..218,288..290,
294..296,300..320)
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/note="Ubq - UCH interaction site; other site"
/db_xref="CDD:176398"
misc_feature order(108..110,114..116,222..224,228..239,294..296,
300..302,306..308,318..320)
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/note="Ubq - CUE interaction site; other site"
/db_xref="CDD:176398"
misc_feature 294..296
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/experiment="experimental evidence, no additional details
recorded"
/note="Essential for function; propagated from
UniProtKB/Swiss-Prot (P62987.2); other site"
misc_feature 321..476
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/note="Ribosomal L40e family; Region: Ribosomal_L40e;
cl00671"
/db_xref="CDD:242019"
mat_peptide 321..476
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/product="ribosomal protein L40"
misc_feature 354..356
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-acetyllysine; propagated from
UniProtKB/Swiss-Prot (P62987.2); acetylation site"
misc_feature 363..437
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/note="Region: zinc finger-like domain"
variation 101
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:374608896"
variation 160
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:377710090"
variation 176
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:149235073"
exon 196..282
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/inference="alignment:Splign:1.39.8"
variation 254
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:144612652"
exon 283..385
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/inference="alignment:Splign:1.39.8"
variation 325
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:148474544"
variation 362
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:142625655"
variation 365
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:146010634"
variation 377
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:11548222"
exon 386..2789
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/inference="alignment:Splign:1.39.8"
variation 403
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="t"
/db_xref="dbSNP:11548223"
variation 424
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="g"
/db_xref="dbSNP:369782459"
variation 430
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="g"
/db_xref="dbSNP:201347795"
variation 431
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="g"
/db_xref="dbSNP:139916590"
STS 435..543
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/standard_name="G62023"
/db_xref="UniSTS:139108"
variation 460
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="c"
/db_xref="dbSNP:144337141"
variation 483
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="g"
/replace="t"
/db_xref="dbSNP:6554"
variation 490
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:200013581"
variation 502..503
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace=""
/replace="c"
/db_xref="dbSNP:34040670"
variation 516
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="g"
/db_xref="dbSNP:3209501"
polyA_signal 537..542
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
variation 553
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:5031054"
variation 566
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="g"
/db_xref="dbSNP:5031053"
variation 569
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:113696080"
polyA_site 570
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/experiment="experimental evidence, no additional details
recorded"
/note="predominant polyadenylation site"
STS 617..799
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/standard_name="RH104429"
/db_xref="UniSTS:98754"
variation 695
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:117335930"
variation 721
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace=""
/replace="t"
/db_xref="dbSNP:41293579"
polyA_site 772
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/experiment="experimental evidence, no additional details
recorded"
variation 800
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="g"
/db_xref="dbSNP:41293581"
variation 1000
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="g"
/db_xref="dbSNP:192716180"
variation 1062..1063
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace=""
/replace="t"
/db_xref="dbSNP:200005880"
variation 1067..1069
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace=""
/replace="ttg"
/db_xref="dbSNP:201195780"
variation 1069..1076
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace=""
/replace="gtttgttt"
/db_xref="dbSNP:369757047"
variation 1069..1071
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace=""
/replace="gtt"
/db_xref="dbSNP:372719515"
variation 1106
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="cc"
/replace="t"
/db_xref="dbSNP:371473226"
variation 1106
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:7258573"
variation 1115
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="g"
/replace="t"
/db_xref="dbSNP:147550993"
STS 1117..1219
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/standard_name="D11S2921"
/db_xref="UniSTS:152074"
variation 1137
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="g"
/db_xref="dbSNP:142064803"
variation 1140
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="g"
/db_xref="dbSNP:7254004"
variation 1150
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="g"
/db_xref="dbSNP:41293583"
variation 1167
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:41293585"
STS 1179..1268
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/standard_name="D8S2279"
/db_xref="UniSTS:473907"
STS 1204..1937
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/standard_name="D14S594"
/db_xref="UniSTS:30246"
STS 1250..2416
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/standard_name="D11S3114"
/db_xref="UniSTS:152207"
variation 1278
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="g"
/db_xref="dbSNP:147940113"
variation 1300
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:41293587"
variation 1322
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="g"
/db_xref="dbSNP:184727297"
variation 1329
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:11672297"
variation 1361
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:188320618"
variation 1366
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:41293589"
variation 1375
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:370949427"
variation 1516
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:41293591"
variation 1558
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="g"
/db_xref="dbSNP:41293593"
variation 1572
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="g"
/db_xref="dbSNP:191281440"
variation 1620
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:41293595"
variation 1694
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:10425018"
variation 1744
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="t"
/db_xref="dbSNP:12610537"
variation 1928
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="g"
/db_xref="dbSNP:184809769"
variation 2052
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="g"
/replace="t"
/db_xref="dbSNP:12608925"
variation 2055
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="g"
/db_xref="dbSNP:74180889"
variation 2084
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="g"
/db_xref="dbSNP:41293597"
variation 2143
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="g"
/db_xref="dbSNP:114386162"
variation 2150
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:41293599"
variation 2261
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="g"
/replace="t"
/db_xref="dbSNP:41293601"
variation 2304..2305
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace=""
/replace="tt"
/db_xref="dbSNP:376674368"
variation 2306
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="t"
/db_xref="dbSNP:80186378"
variation 2341
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:73529590"
variation 2346
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:189254083"
variation 2368
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="g"
/db_xref="dbSNP:10412458"
variation 2440
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:41293603"
STS 2509..2644
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/standard_name="RH92993"
/db_xref="UniSTS:85519"
variation 2516
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:10412696"
variation 2546
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:12150991"
variation 2634
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="g"
/db_xref="dbSNP:28485448"
variation 2645
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace=""
/replace="c"
/db_xref="dbSNP:368863816"
variation 2726
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:1127189"
variation 2742
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="c"
/replace="t"
/db_xref="dbSNP:143239553"
polyA_signal 2771..2776
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
variation 2775
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
/replace="a"
/replace="g"
/db_xref="dbSNP:41293605"
polyA_site 2789
/gene="UBA52"
/gene_synonym="CEP52; HUBCEP52; L40; RPL40"
ORIGIN
gctccgtgcgcaagcgctttcggcggcgattaggtggtttccggttccgctatcttctttttcttcagcgaggcggccgagctgacgcaaacatgcagatctttgtgaagaccctcactggcaaaaccatcacccttgaggtcgagcccagtgacaccattgagaatgtcaaagccaaaattcaagacaaggagggtatcccacctgaccagcagcgtctgatatttgccggcaaacagctggaggatggccgcactctctcagactacaacatccagaaagagtccaccctgcacctggtgttgcgcctgcgaggtggcattattgagccttctctccgccagcttgcccagaaatacaactgcgacaagatgatctgccgcaagtgctatgctcgccttcaccctcgtgctgtcaactgccgcaagaagaagtgtggtcacaccaacaacctgcgtcccaagaagaaggtcaaataaggtggttctttccttgaagggcagcctcctgcccaggccccgtggccctggagcctcaataaagtgtccctttcattgactggagcagcaattggtgtcctcatggctgatctgtccagggaggtggctgaagagtgggcatctcccttagggactctactcagcactccattctgtgccacctgtggggtcttctgtcctagattctgtcacatcggcattggtccctgccctatgcccctgactctggatttgtcatctgtaaaactggagtaaaaacctcagtcgtgtaattggtgggactgaggatcagttttgtcattgctgggatcctgtcaggcactttgaggtgtccctcaggccttggccctgaagtgtctaggtgtgtggagatgggtagaaaattaggtacacccaatggtgtagaacgttgattctcaaatttttttattttatacaaatggggtctcactatgttgtccaggctggtcttgaactcctgggctcaagccatccgcccatctcagcccctcaaagtgttgggattacaagcaagaactgccatgcctgacccagttctcagttttttgtttgtttgtttgtttgtttgttttgagacggagtcttgctctgtcgcccaggctggagtgcagtggcgcagtctcggcttactacaacctctgcctccggggttcacatccttctcctgcctcagcctcccgagtagctgggactacaggtgcccgccacaactcctggctaattttttgtatttttagtagagacggggtttcactgggttagccaggttggtctcgatctcctgaccttgtgatccattcgccttggcctcccagaatgctggtattacaggcgtgagccagcacgcctggcccagttactcagttttgaatctgaggccgtgacatcactcatggtctgcagtcagtgctctgcccctgagctgtaccctctcctatgataatcactcttaagaagggcaacccttggtgttttccccttaaggtcacccaggctggaatgcagtggtgtggtcatggctccctgtaccctggaactcaggcttgggtgatcctctctcctttgcctccgaagtagccaggactacaggtgtgcacccaccaccacactcagataattgctttggtgtttttaaagcttgtaatgatcagtaggctgaggtgggcaaatcataaggtcaagagttttttagatggggtgagcacagaccaattcctgttttatttactgatttaaaattttgagacagtctcactgtcacccaggttggggtgcagtggtaggatcatagcttgctgcagccttgatctcccaggatcttgcctcagcctcccgagtagctgggactgcatgcttgtgccaccacactcggttaatattttgtagagatggggtcttgctatgttgcccaggctggcttcaaactcctgaacttaaaagcctcctgtttagttttggttttttatcactttttttttttttttttgagatggagccttgctcccatcgtgcaggctggagtgcggtggcgcagtctcggctcactgcagcttctgcctctcgggttcaagcgattctcctttctcagcctcttgagtagctggaattaccagtgtgcgccaccaccaccacgcctggctagtttttctgtttttagtagagacagggttttgctatgttggccaggctggtcttgaactactgacctcttgtgatctacctgtcttggccttccaaagtgctaggattacaagcgtaagccacagcgcctggccttgctacatttttttttttttttttttttttacagacatggtctcgctatgttgcccagaatggttttgcactgggtccaagcagttctgccgcagcctcccaaagtgctgggattacaggggtgaggcaccttgctggcccctgttttgattagggtgcagtgctggtgaagccggtgcacgaggccagtgatgcatcctaatgaggggtggagttggcgggacttcctgggccagtttggggactttcacaaaagacccccatgactcagggttttgagttcttaactgatcgaatgaaggattcaaaattaaccactccaaggggggattgaaggaagaaccactcttaatggacaaaaagaaagaaaggggagggagtaacagggatatgagctctagccgcccaagctagcaatggcaacccttctgggtccccttccagcatgtggaagctttcctttcgcttcattcaataaacagctgctgctcaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:7311 -> Molecular function: GO:0003735 [structural constituent of ribosome] evidence: IEA
GeneID:7311 -> Molecular function: GO:0003735 [structural constituent of ribosome] evidence: NAS
GeneID:7311 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:7311 -> Biological process: GO:0000082 [G1/S transition of mitotic cell cycle] evidence: TAS
GeneID:7311 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: TAS
GeneID:7311 -> Biological process: GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] evidence: TAS
GeneID:7311 -> Biological process: GO:0000187 [activation of MAPK activity] evidence: TAS
GeneID:7311 -> Biological process: GO:0000209 [protein polyubiquitination] evidence: TAS
GeneID:7311 -> Biological process: GO:0000278 [mitotic cell cycle] evidence: TAS
GeneID:7311 -> Biological process: GO:0002224 [toll-like receptor signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] evidence: TAS
GeneID:7311 -> Biological process: GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent] evidence: TAS
GeneID:7311 -> Biological process: GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0002756 [MyD88-independent toll-like receptor signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0006281 [DNA repair] evidence: TAS
GeneID:7311 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: TAS
GeneID:7311 -> Biological process: GO:0006367 [transcription initiation from RNA polymerase II promoter] evidence: TAS
GeneID:7311 -> Biological process: GO:0006412 [translation] evidence: NAS
GeneID:7311 -> Biological process: GO:0006412 [translation] evidence: TAS
GeneID:7311 -> Biological process: GO:0006413 [translational initiation] evidence: TAS
GeneID:7311 -> Biological process: GO:0006414 [translational elongation] evidence: TAS
GeneID:7311 -> Biological process: GO:0006415 [translational termination] evidence: TAS
GeneID:7311 -> Biological process: GO:0006464 [cellular protein modification process] evidence: TAS
GeneID:7311 -> Biological process: GO:0006614 [SRP-dependent cotranslational protein targeting to membrane] evidence: TAS
GeneID:7311 -> Biological process: GO:0006915 [apoptotic process] evidence: TAS
GeneID:7311 -> Biological process: GO:0006977 [DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest] evidence: TAS
GeneID:7311 -> Biological process: GO:0007173 [epidermal growth factor receptor signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0007179 [transforming growth factor beta receptor signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0007219 [Notch signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0007220 [Notch receptor processing] evidence: TAS
GeneID:7311 -> Biological process: GO:0007249 [I-kappaB kinase/NF-kappaB cascade] evidence: TAS
GeneID:7311 -> Biological process: GO:0007254 [JNK cascade] evidence: TAS
GeneID:7311 -> Biological process: GO:0008543 [fibroblast growth factor receptor signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0010467 [gene expression] evidence: TAS
GeneID:7311 -> Biological process: GO:0016032 [viral process] evidence: TAS
GeneID:7311 -> Biological process: GO:0016044 [cellular membrane organization] evidence: TAS
GeneID:7311 -> Biological process: GO:0016070 [RNA metabolic process] evidence: TAS
GeneID:7311 -> Biological process: GO:0016071 [mRNA metabolic process] evidence: TAS
GeneID:7311 -> Biological process: GO:0016197 [endosomal transport] evidence: TAS
GeneID:7311 -> Biological process: GO:0019058 [viral infectious cycle] evidence: TAS
GeneID:7311 -> Biological process: GO:0019067 [viral assembly, maturation, egress, and release] evidence: TAS
GeneID:7311 -> Biological process: GO:0019068 [virion assembly] evidence: TAS
GeneID:7311 -> Biological process: GO:0019082 [viral protein processing] evidence: TAS
GeneID:7311 -> Biological process: GO:0019083 [viral transcription] evidence: TAS
GeneID:7311 -> Biological process: GO:0019221 [cytokine-mediated signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0030512 [negative regulation of transforming growth factor beta receptor signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0031145 [anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process] evidence: TAS
GeneID:7311 -> Biological process: GO:0032479 [regulation of type I interferon production] evidence: TAS
GeneID:7311 -> Biological process: GO:0032480 [negative regulation of type I interferon production] evidence: TAS
GeneID:7311 -> Biological process: GO:0032481 [positive regulation of type I interferon production] evidence: TAS
GeneID:7311 -> Biological process: GO:0034134 [toll-like receptor 2 signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0034138 [toll-like receptor 3 signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0034142 [toll-like receptor 4 signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0034146 [toll-like receptor 5 signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0034162 [toll-like receptor 9 signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0034166 [toll-like receptor 10 signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0034220 [ion transmembrane transport] evidence: TAS
GeneID:7311 -> Biological process: GO:0035666 [TRIF-dependent toll-like receptor signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0035872 [nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0038095 [Fc-epsilon receptor signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0042059 [negative regulation of epidermal growth factor receptor signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I] evidence: TAS
GeneID:7311 -> Biological process: GO:0042981 [regulation of apoptotic process] evidence: TAS
GeneID:7311 -> Biological process: GO:0043065 [positive regulation of apoptotic process] evidence: TAS
GeneID:7311 -> Biological process: GO:0043066 [negative regulation of apoptotic process] evidence: TAS
GeneID:7311 -> Biological process: GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB cascade] evidence: TAS
GeneID:7311 -> Biological process: GO:0044267 [cellular protein metabolic process] evidence: TAS
GeneID:7311 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
GeneID:7311 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: TAS
GeneID:7311 -> Biological process: GO:0046788 [egress of virus within host cell] evidence: TAS
GeneID:7311 -> Biological process: GO:0048011 [neurotrophin TRK receptor signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0050852 [T cell receptor signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0051092 [positive regulation of NF-kappaB transcription factor activity] evidence: TAS
GeneID:7311 -> Biological process: GO:0051403 [stress-activated MAPK cascade] evidence: TAS
GeneID:7311 -> Biological process: GO:0051436 [negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle] evidence: TAS
GeneID:7311 -> Biological process: GO:0051437 [positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle] evidence: TAS
GeneID:7311 -> Biological process: GO:0051439 [regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle] evidence: TAS
GeneID:7311 -> Biological process: GO:0055085 [transmembrane transport] evidence: TAS
GeneID:7311 -> Biological process: GO:0061418 [regulation of transcription from RNA polymerase II promoter in response to hypoxia] evidence: TAS
GeneID:7311 -> Biological process: GO:0070423 [nucleotide-binding oligomerization domain containing signaling pathway] evidence: TAS
GeneID:7311 -> Biological process: GO:0071456 [cellular response to hypoxia] evidence: TAS
GeneID:7311 -> Biological process: GO:0097190 [apoptotic signaling pathway] evidence: TAS
GeneID:7311 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
GeneID:7311 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:7311 -> Cellular component: GO:0005840 [ribosome] evidence: IEA
GeneID:7311 -> Cellular component: GO:0005886 [plasma membrane] evidence: TAS
GeneID:7311 -> Cellular component: GO:0010008 [endosome membrane] evidence: TAS
GeneID:7311 -> Cellular component: GO:0022625 [cytosolic large ribosomal subunit] evidence: IDA
GeneID:7311 -> Cellular component: GO:0030666 [endocytic vesicle membrane] evidence: TAS
by
@meso_cacase at
DBCLS
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